(data stored in ACNUC7421 zone)

SWISSPROT: Q82R98_STRAW

ID   Q82R98_STRAW            Unreviewed;       224 AA.
AC   Q82R98;
DT   01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2003, sequence version 1.
DT   08-MAY-2019, entry version 80.
DE   SubName: Full=Putative LysE-family efflux protein {ECO:0000313|EMBL:BAC67954.1};
GN   ORFNames=SAVERM_245 {ECO:0000313|EMBL:BAC67954.1};
OS   Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 /
OS   NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=227882 {ECO:0000313|EMBL:BAC67954.1, ECO:0000313|Proteomes:UP000000428};
RN   [1] {ECO:0000313|EMBL:BAC67954.1, ECO:0000313|Proteomes:UP000000428}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC   NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX   PubMed=11572948; DOI=10.1073/pnas.211433198;
RA   Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C.,
RA   Shinose M., Takahashi Y., Horikawa H., Nakazawa H., Osonoe T.,
RA   Kikuchi H., Shiba T., Sakaki Y., Hattori M.;
RT   "Genome sequence of an industrial microorganism Streptomyces
RT   avermitilis: deducing the ability of producing secondary
RT   metabolites.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001).
RN   [2] {ECO:0000313|EMBL:BAC67954.1, ECO:0000313|Proteomes:UP000000428}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC   NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX   PubMed=12692562; DOI=10.1038/nbt820;
RA   Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T.,
RA   Sakaki Y., Hattori M., Omura S.;
RT   "Complete genome sequence and comparative analysis of the industrial
RT   microorganism Streptomyces avermitilis.";
RL   Nat. Biotechnol. 21:526-531(2003).
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DR   EMBL; BA000030; BAC67954.1; -; Genomic_DNA.
DR   RefSeq; WP_010981681.1; NZ_BAVY01000070.1.
DR   EnsemblBacteria; BAC67954; BAC67954; SAVERM_245.
DR   KEGG; sma:SAVERM_245; -.
DR   eggNOG; COG1280; LUCA.
DR   HOGENOM; HOG000122945; -.
DR   OMA; VFLLNVT; -.
DR   OrthoDB; 1927576at2; -.
DR   BioCyc; SAVE227882:G1G23-270-MONOMER; -.
DR   Proteomes; UP000000428; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0006865; P:amino acid transport; IEA:InterPro.
DR   InterPro; IPR001123; LeuE-type.
DR   PANTHER; PTHR30086; PTHR30086; 1.
DR   Pfam; PF01810; LysE; 1.
DR   PIRSF; PIRSF006324; LeuE; 1.
PE   4: Predicted;
DR   PRODOM; Q82R98.
DR   SWISS-2DPAGE; Q82R98.
KW   Cell membrane {ECO:0000256|SAAS:SAAS00177378};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000428};
KW   Membrane {ECO:0000256|SAAS:SAAS00177306, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000428};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00177323,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00177374,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM      6     27       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     39     62       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     68     90       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    136    156       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    168    192       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    204    223       Helical. {ECO:0000256|SAM:Phobius}.
SQ   SEQUENCE   224 AA;  23528 MW;  B36F80F08556E995 CRC64;
     MSVDLVGFLG VVLVAYVVPG PDFLVVVRSA TEHPAKGRAA ALGAQSGLCV HMLAAAVGLS
     LIAARSPAVY DAIRLLGAAY LVYLGVRAVL AARRAARERA AGREAVGGVE DGTDPRTPEE
     EAPAHGRWRS GFTQGFLTNV LNPKAALFFL SILPQFVHGG GSTSRQIFFL GTLDIVIGVA
     YWFALVAVAA RLRAFLARPK VRHGWELTTG WLFIAIGIGV AAAA
//

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