SWISSPROT: Q82QU1_STRAW

ID   Q82QU1_STRAW            Unreviewed;       518 AA.
AC   Q82QU1;
DT   01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2003, sequence version 1.
DT   08-MAY-2019, entry version 97.
DE   SubName: Full=Putative pyridine nucleotide transhydrogenase, alpha subunit {ECO:0000313|EMBL:BAC68113.1};
GN   Name=pntA {ECO:0000313|EMBL:BAC68113.1};
GN   ORFNames=SAVERM_404 {ECO:0000313|EMBL:BAC68113.1};
OS   Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 /
OS   NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=227882 {ECO:0000313|EMBL:BAC68113.1, ECO:0000313|Proteomes:UP000000428};
RN   [1] {ECO:0000313|EMBL:BAC68113.1, ECO:0000313|Proteomes:UP000000428}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC   NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX   PubMed=11572948; DOI=10.1073/pnas.211433198;
RA   Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C.,
RA   Shinose M., Takahashi Y., Horikawa H., Nakazawa H., Osonoe T.,
RA   Kikuchi H., Shiba T., Sakaki Y., Hattori M.;
RT   "Genome sequence of an industrial microorganism Streptomyces
RT   avermitilis: deducing the ability of producing secondary
RT   metabolites.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001).
RN   [2] {ECO:0000313|EMBL:BAC68113.1, ECO:0000313|Proteomes:UP000000428}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC   NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX   PubMed=12692562; DOI=10.1038/nbt820;
RA   Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T.,
RA   Sakaki Y., Hattori M., Omura S.;
RT   "Complete genome sequence and comparative analysis of the industrial
RT   microorganism Streptomyces avermitilis.";
RL   Nat. Biotechnol. 21:526-531(2003).
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DR   EMBL; BA000030; BAC68113.1; -; Genomic_DNA.
DR   RefSeq; WP_010981840.1; NZ_JZJK01000056.1.
DR   STRING; 227882.SAV_404; -.
DR   EnsemblBacteria; BAC68113; BAC68113; SAVERM_404.
DR   KEGG; sma:SAVERM_404; -.
DR   eggNOG; ENOG4107QWH; Bacteria.
DR   eggNOG; COG3288; LUCA.
DR   HOGENOM; HOG000022121; -.
DR   KO; K00324; -.
DR   OMA; VIGHVHH; -.
DR   OrthoDB; 464096at2; -.
DR   BioCyc; SAVE227882:G1G23-451-MONOMER; -.
DR   Proteomes; UP000000428; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008746; F:NAD(P)+ transhydrogenase activity; IEA:InterPro.
DR   GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR   InterPro; IPR008142; AlaDH/PNT_CS1.
DR   InterPro; IPR007886; AlaDH/PNT_N.
DR   InterPro; IPR007698; AlaDH/PNT_NAD(H)-bd.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR026255; NADP_transhyd_a.
DR   InterPro; IPR024605; NADP_transhyd_a_C.
DR   Pfam; PF01262; AlaDh_PNT_C; 1.
DR   Pfam; PF05222; AlaDh_PNT_N; 1.
DR   Pfam; PF12769; PNTB_4TM; 1.
DR   PIRSF; PIRSF000203; NADP_transhydrogenase_alpha; 1.
DR   SMART; SM01002; AlaDh_PNT_C; 1.
DR   SMART; SM01003; AlaDh_PNT_N; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   TIGRFAMs; TIGR00561; pntA; 1.
DR   PROSITE; PS00836; ALADH_PNT_1; 1.
PE   4: Predicted;
DR   PRODOM; Q82QU1.
DR   SWISS-2DPAGE; Q82QU1.
KW   Complete proteome {ECO:0000313|Proteomes:UP000000428};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000428};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    407    426       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    432    449       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    461    479       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    485    507       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       15    145       AlaDh_PNT_N. {ECO:0000259|SMART:SM01003}.
FT   DOMAIN      154    318       AlaDh_PNT_C. {ECO:0000259|SMART:SM01002}.
SQ   SEQUENCE   518 AA;  53305 MW;  753144BB2ED3FEDA CRC64;
     MSAQKPSHHP PRRIGVVAES VSGETRVAAT PATVRLLLGL GYEVVVESGA GEASGFGDQA
     YADAGAGIGE AWDADVVLKV NAPSDAEICR LRKGATVVAL LTPAQKPELL QALADAGVTA
     LALDAVPRIS RAQSMDVLSS MANIAGYRAV IEAAHAFGRF FTGQVTAAGK VPPAKVLVAG
     AGVAGLAAIG AASSLGAIVR ATDPRPEVAD QVKSLGGEYL PVEAVQESST DGYAKATSAD
     YDRAAAQLYH EQAEDVDMVI TTALIPGRPA PRLLTAEDVA VMKSGSVIVD MAAAMGGNVE
     GTVPGRTVVT DNGVTIIGYT DLASRLPAQA SQLFGTNLLN LLKLLTPGKD GQLTVDFDDV
     VQRAVTVVRD GDVTWPPPPV AVSAAPAAQP AAAPVAPEPK QSNLTPAWRF GLIGLGMLAM
     FLLVAFAPTQ LAGNFTVFAL AVVIGYYVIG KVHHALHTPL MSVTNAISGI VVIGALLQIG
     HESWIVTTLS FVAILLTSVN IFGGFAVTRR MLSMFSKG
//