(data stored in ACNUC7421 zone)

SWISSPROT: B1VNF1_STRGG

ID   B1VNF1_STRGG            Unreviewed;       237 AA.
AC   B1VNF1;
DT   20-MAY-2008, integrated into UniProtKB/TrEMBL.
DT   20-MAY-2008, sequence version 1.
DT   07-JUN-2017, entry version 71.
DE   RecName: Full=Deoxyribose-phosphate aldolase {ECO:0000256|SAAS:SAAS00678636};
DE            EC=4.1.2.4 {ECO:0000256|SAAS:SAAS00678636};
GN   OrderedLocusNames=SGR_145 {ECO:0000313|EMBL:BAG16974.1};
OS   Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=455632 {ECO:0000313|EMBL:BAG16974.1, ECO:0000313|Proteomes:UP000001685};
RN   [1] {ECO:0000313|EMBL:BAG16974.1, ECO:0000313|Proteomes:UP000001685}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 4626 / NBRC 13350 {ECO:0000313|Proteomes:UP000001685};
RX   PubMed=18375553; DOI=10.1128/JB.00204-08;
RA   Ohnishi Y., Ishikawa J., Hara H., Suzuki H., Ikenoya M., Ikeda H.,
RA   Yamashita A., Hattori M., Horinouchi S.;
RT   "Genome sequence of the streptomycin-producing microorganism
RT   Streptomyces griseus IFO 13350.";
RL   J. Bacteriol. 190:4050-4060(2008).
CC   -!- FUNCTION: Catalyzes a reversible aldol reaction between
CC       acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-
CC       D-ribose 5-phosphate. {ECO:0000256|SAAS:SAAS00678635}.
CC   -!- CATALYTIC ACTIVITY: 2-deoxy-D-ribose 5-phosphate = D-
CC       glyceraldehyde 3-phosphate + acetaldehyde.
CC       {ECO:0000256|SAAS:SAAS00678634}.
CC   -!- PATHWAY: Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate
CC       degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-
CC       deoxy-alpha-D-ribose 1-phosphate: step 2/2.
CC       {ECO:0000256|SAAS:SAAS00535480}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|SAAS:SAAS00535486}.
CC   -!- SIMILARITY: Belongs to the DeoC/FbaB aldolase family. DeoC type 1
CC       subfamily. {ECO:0000256|SAAS:SAAS00535487}.
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DR   EMBL; AP009493; BAG16974.1; -; Genomic_DNA.
DR   RefSeq; WP_003964019.1; NC_010572.1.
DR   ProteinModelPortal; B1VNF1; -.
DR   STRING; 455632.SGR_145; -.
DR   EnsemblBacteria; BAG16974; BAG16974; SGR_145.
DR   GeneID; 6211718; -.
DR   KEGG; sgr:SGR_145; -.
DR   PATRIC; fig|455632.4.peg.129; -.
DR   eggNOG; ENOG4108PMK; Bacteria.
DR   eggNOG; COG0274; LUCA.
DR   HOGENOM; HOG000241645; -.
DR   KO; K01619; -.
DR   OMA; KIATVTN; -.
DR   UniPathway; UPA00002; UER00468.
DR   Proteomes; UP000001685; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004139; F:deoxyribose-phosphate aldolase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009264; P:deoxyribonucleotide catabolic process; IEA:InterPro.
DR   GO; GO:0046386; P:deoxyribose phosphate catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0042558; P:pteridine-containing compound metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR011343; DeoC.
DR   InterPro; IPR002915; DeoC/FbaB/lacD_aldolase.
DR   InterPro; IPR028581; DeoC_typeI.
DR   InterPro; IPR000489; Pterin-binding_dom.
DR   PANTHER; PTHR10889; PTHR10889; 1.
DR   PANTHER; PTHR10889:SF9; PTHR10889:SF9; 1.
DR   PIRSF; PIRSF001357; DeoC; 1.
DR   SMART; SM01133; DeoC; 1.
DR   TIGRFAMs; TIGR00126; deoC; 1.
DR   PROSITE; PS50972; PTERIN_BINDING; 1.
PE   3: Inferred from homology;
DR   PRODOM; B1VNF1.
DR   SWISS-2DPAGE; B1VNF1.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001685};
KW   Cytoplasm {ECO:0000256|SAAS:SAAS00535479};
KW   Lyase {ECO:0000256|SAAS:SAAS00678637};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001685};
KW   Schiff base {ECO:0000256|SAAS:SAAS00678625}.
FT   DOMAIN       59    237       Pterin-binding. {ECO:0000259|PROSITE:
FT                                PS50972}.
SQ   SEQUENCE   237 AA;  24669 MW;  8FF4F5365EC4C750 CRC64;
     MSETTVKPGE LNLTPAELAP FIQHTKIDPD ATRDEMIAHA QEAVTHGFNA AMVPASWLPL
     VVAELKGTGV EVASALDFPS VGVMTSAGKA AEAAEIARLG ADQLDMGVQV GWLKSGRYDD
     FREDIAGVVR ASGLPVKVML ELPLLTDAEK EAAVELAMEA GASFLKNASS GQIETANPTS
     VRYLVERARE GVRVKASGSI KSYGQGLELL RAGASLLGTS AGLAIITDTG DASTASY
//

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