(data stored in ACNUC7421 zone)

SWISSPROT: C1AR31_RHOOB

ID   C1AR31_RHOOB            Unreviewed;      9855 AA.
AC   C1AR31;
DT   26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   26-MAY-2009, sequence version 1.
DT   30-AUG-2017, entry version 56.
DE   SubName: Full=Putative non-ribosomal peptide synthetase {ECO:0000313|EMBL:BAH48508.1};
GN   OrderedLocusNames=ROP_02610 {ECO:0000313|EMBL:BAH48508.1};
OS   Rhodococcus opacus (strain B4).
OC   Bacteria; Actinobacteria; Corynebacteriales; Nocardiaceae;
OC   Rhodococcus.
OX   NCBI_TaxID=632772 {ECO:0000313|EMBL:BAH48508.1, ECO:0000313|Proteomes:UP000002212};
RN   [1] {ECO:0000313|EMBL:BAH48508.1, ECO:0000313|Proteomes:UP000002212}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=B4 {ECO:0000313|EMBL:BAH48508.1,
RC   ECO:0000313|Proteomes:UP000002212};
RA   Takarada H., Sekine M., Hosoyama A., Yamada R., Fujisawa T., Omata S.,
RA   Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S.;
RT   "Comparison of the complete genome sequences of Rhodococcus
RT   erythropolis PR4 and Rhodococcus opacus B4.";
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00258}.
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DR   EMBL; AP011115; BAH48508.1; -; Genomic_DNA.
DR   ProteinModelPortal; C1AR31; -.
DR   STRING; 632772.ROP_02610; -.
DR   EnsemblBacteria; BAH48508; BAH48508; ROP_02610.
DR   KEGG; rop:ROP_02610; -.
DR   PATRIC; fig|632772.20.peg.301; -.
DR   eggNOG; ENOG4105C0W; Bacteria.
DR   eggNOG; COG1020; LUCA.
DR   HOGENOM; HOG000229991; -.
DR   OMA; HISGDGW; -.
DR   OrthoDB; POG091H088I; -.
DR   BioCyc; ROPA632772:GH0Q-260-MONOMER; -.
DR   Proteomes; UP000002212; Chromosome.
DR   GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR   GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   InterPro; IPR010071; AA_adenyl_domain.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig.
DR   InterPro; IPR001242; Condensatn.
DR   InterPro; IPR020806; PKS_PP-bd.
DR   InterPro; IPR020802; PKS_thioesterase.
DR   InterPro; IPR009081; PP-bd_ACP.
DR   InterPro; IPR006162; Ppantetheine_attach_site.
DR   InterPro; IPR001031; Thioesterase.
DR   Pfam; PF00501; AMP-binding; 9.
DR   Pfam; PF13193; AMP-binding_C; 9.
DR   Pfam; PF00668; Condensation; 9.
DR   Pfam; PF00550; PP-binding; 9.
DR   Pfam; PF00975; Thioesterase; 1.
DR   SMART; SM00823; PKS_PP; 9.
DR   SMART; SM00824; PKS_TE; 1.
DR   SUPFAM; SSF47336; SSF47336; 9.
DR   SUPFAM; SSF53474; SSF53474; 1.
DR   TIGRFAMs; TIGR01733; AA-adenyl-dom; 9.
DR   PROSITE; PS50075; ACP_DOMAIN; 9.
DR   PROSITE; PS00455; AMP_BINDING; 9.
DR   PROSITE; PS00012; PHOSPHOPANTETHEINE; 9.
PE   4: Predicted;
DR   PRODOM; C1AR31.
DR   SWISS-2DPAGE; C1AR31.
KW   Complete proteome {ECO:0000313|Proteomes:UP000002212}.
FT   DOMAIN     1000   1067       Carrier. {ECO:0000259|PROSITE:PS50075}.
FT   DOMAIN     2055   2122       Carrier. {ECO:0000259|PROSITE:PS50075}.
FT   DOMAIN     3119   3186       Carrier. {ECO:0000259|PROSITE:PS50075}.
FT   DOMAIN     4180   4247       Carrier. {ECO:0000259|PROSITE:PS50075}.
FT   DOMAIN     5243   5310       Carrier. {ECO:0000259|PROSITE:PS50075}.
FT   DOMAIN     6307   6374       Carrier. {ECO:0000259|PROSITE:PS50075}.
FT   DOMAIN     7364   7431       Carrier. {ECO:0000259|PROSITE:PS50075}.
FT   DOMAIN     8429   8496       Carrier. {ECO:0000259|PROSITE:PS50075}.
FT   DOMAIN     9488   9555       Carrier. {ECO:0000259|PROSITE:PS50075}.
FT   MOD_RES    4212   4212       O-(pantetheine 4'-phosphoryl)serine.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00258}.
FT   MOD_RES    5275   5275       O-(pantetheine 4'-phosphoryl)serine.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00258}.
FT   MOD_RES    6339   6339       O-(pantetheine 4'-phosphoryl)serine.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00258}.
SQ   SEQUENCE   9855 AA;  1057727 MW;  F026ED15083C1071 CRC64;
     MGSFPPPEWE MRTNKVVEAV PGGEVTAHGR IPDGAFPLSA AQRGMWFAQQ LDPSVPVTIA
     QCVELVGALD VALLSESLIT AGRELGSAFL RLVEVDGVPY QLIDPTLEAS VSVVDLQHEP
     DPRAAATEWM RQEYTTPLDV CRDRLVTSAV LRIGPNHHYW YCRVHHVALD GMGSVTLVDR
     TAELYTAAVE GRAVAPSKAA ELTDVARVDD EYRTSSRYLA DGEYWSERVS SIGEPHSLVD
     RTAPARARSR TTGGQILGPL ADHLDAATNR HDSSAAFEVI AAFAAYLARM TGREEVAVSL
     PVTARTTALL RRSGGMVSNV VPLRLDVRPD MTNTDLVAAV RLEVTGALRH QRYPHMDIRR
     DAATDHQGFY GPLINVMLFH NEITLGSIVG RLELLSTGPI SDLAVNVYHG VAGTSINLDL
     EANPDLYSDD ALAAHHARFT RFLGAFLTSD TGTPRRIGDL EILDEDECRI LVPAAGRAGF
     APVALPDLLA GAVRSNPDGD ALVAPGHGTP DVTLSYRALD EESNRLARLL IDLQVGPEVS
     VALALPRSVE SVSSVWAVAK SGAAFVPVDP GYPFERIVHM LEDCGAPIGI TTAALRAGLP
     DSTLWLVLDD DEFVSAVAAY PADPVTDADR TGVLMVDHPA YVIYTSGSTG RPKGVAVSHR
     GVVNLAADER DRLGVSADSR VLHFASPSFD ASVFELVMAV CAGAALVVAP TTMFGGVELA
     EFLAEHEVSH AFCTPAALAS LDHRGLDHLT TVVVAGDVCP PELVAKWAPG RIMVNAYGPT
     ETTIMSSATG PMVPGQPVTI GSATVGVDLV VLDHRLRPVP VGVRGELYVL GSSLARGYVH
     RAGLTAERFV ASPFGTGGRM YRTGDVVRWG TVPDGPPVLE FLGRSDFQVK IRGFRIELGE
     IDAALSAHPV VEFAHTVGYD DGSGRSRLVS YVLPAPGTDV ETRVLSEFVG TRLPGYMVPS
     SIMVLNMLPL TPAGKLDRNA LPAPVFAARS ADIVRPRTVS EEILLGIFRD VLGLPELSVD
     TSFFELGGNS LMATQVVSRV NAALDVRIGV RDLFQSPSVS KLAATVANAG PQSDPRPALE
     PRERPDRMPL SVAQQRMWFL NQFDTASAAY NLPIALRLAG ALDREALRAA LGDVQERHEA
     LRTVFPDSAD GPHQLIKPAV SVLADTDPLD VDPESLTAAV TALGSTGFDL TADTPLRAGL
     FREAPERHVL VLVVHHIAAD GWSMTPLAAD VMVAYAARAA GHAPIWAPLP VQYVDYSLWQ
     RDLLGSEDDP NSLSAKQIAH WRAALAGVPQ LIELPTDRTR PAEMSHRGGR VEFTIPADVH
     GRLVDLAQST GTTPFMVTHA ALAVLLRRLG AGSDIVIGTP VAGRGEEALD HLVGMFVNTL
     ALRTTVDLGD TFEDVLARTR AADLAAFQHG DVPFERLVEV LSPARSSAHH PLFQVMLTFQ
     NTANTRVELD GLEVEAAEID VQVAKFDLHL TVAENVDAAG NAAGLAVQLS YATDLFDHST
     VVSIGERFGR LLDAVSGNPP VAVGDLDLLD SREHAALTAA NATHRPVPAD TLASLFAAQA
     AATPDAVALV FDDRRLTYAE FDERTDRLAR HLIRTGVGPE SVVAVGMRRS IDLLVAVYAI
     VKAGAAYLPI DPDHPAERTA YVLDTAQPVC VLTRAADDTT FRTAAPVVNI DTLDLPDQDP
     TPISTALTAG NTAYVIFTSG STGRPKGVAV THGAIVNRLL WMQHEYGLTP DDAVMQKTPV
     TFDVSVWELF WPLQVGASMV IAAPDGHRDP DYLATLIRRH RVTTMHFVPS MLSVFTAEPA
     VAVCDSLRLV FCSGEALTPE QVSRFRAVSG AGLHNLYGPT EAAVDVTYWE TGAADALSVP
     IGRPVWNTQV HVLDARLHPV PNGVAGEVYL AGDQLARGYL NRADLSSDRF VANPFVAGGR
     MYRTGDLVRR RGDGALEYLG RTDFQVKLRG QRIELGEIES ALEAHPDVVQ AVVVVHRDER
     GDEALVAYLV GRRAAEWSDV RAHLSTRVPS YMIPARVVHL DTLPLSVNGK LDRKALPPPT
     LDTATAEYIA PQTPAEVVVA GVFAEILGVE RVGTHDHFFD LGGNSLVATR LVSRLRIALG
     VPVSLRDVFD APTVGALAHR LDRVDPAAHP APPALTPQER PEQVPLSPAQ QRVWFLNQFD
     TSSPVYNLPL AVRFSGGLDV TALRRALRAV LHRHESLRTV FPASDSSPWQ RILDEHDVDL
     DLTVVEATDA ELAAAIRGFA LAGFDVTTEI PVRARLLRVR NDEHVLVLVV HHIAADGWSF
     APLSRDLMVA YAAHSGGRDL QWAPLPVQYA DYTLWQRELL GEKHDPDSRA ARQLAYWATT
     LAGLPDSLDL PTDRPRPSVA SKHGATVSWE ISTELHERLL TLARTQDTTL FMVAHSALSV
     LLSRLSATTD IAIGTPVAGR GDRDLDDLVG MFVNTLVLRA QLDPASSFAE LLQQVREVDL
     AAFAHTDVPF ERLVEHLNPT RTAAHHPLFQ VALFFQNHAP AHLELPGLSV SSQPILPDVA
     AFDLQLVLTD TRDADGTPGP ITAEFNYATE LFDESTIRSF GSQFVRILDA VTMAPHTPVG
     DIAIAHPAAR IRELSGWNAT DHDVPDTTLP DLFGAQAART PDAPAVVFDG ASLTYREFDE
     HANRLARYLI SCGVGPESRV ALAMRRSLDL VVGMYAVVKA GGAYVPVDPD HPADRIGYVL
     QSAGPVCVLT TTADRGALPS GDVVTLDCLD LSDFSGAPVT DADRVYPLRA DNTAYVIYTS
     GSTGKPKGVA VPHAAIVNQL LWMQSQYALT GRDVVLQKTA TTFDVSVWGF FWPLQVGAAL
     VLAGPDGHRD PDYLARTIDE LGVTVTDFVP SMLDVFVASV PADSCSSLRH VFVIGEALPP
     ETASRFRDLS SAGLHNLYGP TEAAVSVTYW ETSDADTVTV PIGVPEWNTQ AYVLDSRLHP
     VAAGVPGELY LGGVQLARGY LGRVDLTSDR FVANPFGGAG ARMYRTGDLV RRRRDGVLEY
     IGRTDFQVKF RGQRIELGEI ETVLRSHPGV TGAAVVVYSD ATTGDHLVAY VVPAPDRVAD
     TAEIRRHASG SLPSYMVPSA VVLLDEFPLN TSGKLDRKAL PAPEFTSDAT EYVAPSTSVE
     RAVASVFCAV LGLERVSVRD SFFELGGNSL IATQLVSRLR GELDVPVTVR DLFETPTVAE
     LAARLSQSTG ADTRPALIRR ERPERIPLSP AQQRMWFLNQ FDPSSPAYNL PFAVRFTGPL
     DRVALEAAVA DLVERHESLR TVFPDSATGP HQVVRDTADA PPNLTVADIA EDELETVLAR
     FFTTGFDVTT DLPVRVTLLR VSAHEHVLAL VVHHICGDGW SMAPMVRDVM VAYTARTRGE
     RPAWTPLPVQ YADYALWQRE LLGDESDPDT LAARQLDYWT DTLAGIPDEL ELPTDHPRPA
     EQSYRGSHVD FDIDASAHRA LAALAQSRRA TLFMVMHTAL AVLLGRLSAS SDVTIGTPVA
     GRGEPELDDL IGMFVNTVAL RTHVDPGSAF TDVLDHVRDV DLAAFSRADV PFERLVEVLS
     PTRHAARHPL FQVMLTFQNL EQTALELDGL TLRGLGTDID VAKFDLHLTL VERFDPAGRP
     DGMTAQLTYA TDLFDADTAD SIAARFTTIL GAVTTDATTR VGDIALLGAD ERAALTLWNS
     TEHAVPATTL PVLFDAQVAR TPGAPALVLD GASLTYREFD EHANRLARYL VSCGVGPESR
     VALAMRRSLD LVVGMYAVVK AGGAYVPVDP DHPADRIGYV LQSAGPVCVL TTAADRGALP
     SGDVVTLDCL DLSDFSGAPV TDADRVYPLR ADNTAYVIYT SGSTGKPKGV AVPHAAIVNQ
     LLWMQSQYAL TGRDVVLQKT ATTFDVSVWG FFWPLQVGAA LVLAGPDGHR DPDYLARTID
     ELGVTVTDFV PSMLDVFVAS VPADSCSSLR HVFVIGEALP PETASRFRDL SSAGLHNLYG
     PTEAAVSVTY WETSDADTVT VPIGVPEWNT QAYVLDSRLH PVAAGVPGEL YLGGVQLARG
     YLGRVDLTSD RFVANPFGGA GARMYRTGDL VRRRRDGVLE YIGRTDFQVK FRGQRIELGE
     IETVLRSHPG VTGAAVVVYS DATTGDHLVA YVVPAPDRVA DTAEIRRHAS GSLPSYMVPS
     AVVLLDEFPL NTSGKLDRKA LPAPEFSSDA TEYVAPRNEV EQALAGVFAD VLGAGRVGVH
     DSFFDLGGNS LSVTRLAARI TETTGTRLSV RDVFEAPTVA DLAVRIDPTA RDVRPALTAA
     PRPARIPLSL AQQRMWLLNQ FDADSPAYNL PFAVRLSGVV DTAALAAAFD DVVERHESLR
     TVFPDGGDGP EQVVLAVTDV SVTLPPVDVT EADLPGRMAA LASRTFDVTA ETPVRATLFR
     TAPTEHVLAI SLHHIAADGW SFGPLGRDVM VAYAARTDGH APQWAPFEVQ YADFSVWQRD
     VLGSEDDPES VLATQLGFWT RTLAGAPDEL PLPFDRPRPA QPTFAGGSVG FDIDPETHRR
     IRSLARDHGA TTFMVAHTAF ALLMARLSAT DDVAIGTPIA GRGERALDDL VGMFVNTLVL
     RTAVNGGATF AEMLRTVRDT DLAAFAHADV PFERLVDALA PTRTAARHPI YQVALSMNPL
     QSPDYELPGL RIGVEDVDPG VAKIDLQLTL GEELDHTGAP SGMRAEFIYA TDLFDESTIS
     DVASRLQRIL EAVTSDPDTL VGDLDLLHDA ERDALVPASG RPGLIPVTLP DLLAGAVRSN
     PDGDALVAPG HGTSDGTLSY RALDATSNRL ARLLIDLQVG PEVSVALALP RSRESVVATW
     AVTKSGAAFV PVDPNYPADR IAFMLEDCGA PIGITTAALR ENLPDSTLWL VLDDDAVIEA
     LTSYSSEPVQ DSDRVAALSV DHPAYLIYTS GSTGRPKGVA VSHRGVVNLA ADERVRLGVL
     SESRVLHFAS PSFDASVFEL MMAVSAGATL VVAPTTIFGG EELAEFLAEQ EVSHAFCTPA
     ALASVNHRGL DSLTTVVVAG DVCPPELVAR WAPGRVMVNA YGPSEATIMS SATGPLVPGQ
     PVTIGSPTVG VDLVVLDSRL RPVPAGVRGE LYVLGSSLAR GYVRRSGLTA ERFVASPFGS
     GGRMYRTGDV VRWVTAPDRP PVLEFLGRSD FQVKIRGFRI ELGEIDAALT AHPVVEFAHT
     IGFDDGSGHD RLVSYVLPAP AAEVDSRVLS EFVGERLPGY MVPSSIMVLD SLPLTPAGKL
     DRNALPTPVF AQRSEFTAPQ TPAEQAIAAV FADVVGEPSI GLDDNFFDLG GNSLSATQVV
     SRVGSALGTR ISVRTLFDNP TVRALATAAA SDTTAERPAL VAGERPATIP LSPAQQRMWF
     LNQFDTTAAA YTIPLALRMS GRIDVATLRT ALGDVLARHE ALRTVYPATE NGAHQVIVPV
     ESIPLDLTPT RLSGEDLSGA ILRHASAGFD VTTDLPLRVH LFRESRSEHV LLFVVHHISA
     DGWSFIPLAS DVMTSYAART AGDAPVWNAL PVQYADYAMW QRHLLGDSDD PQSLAASQIA
     YWKRTLAGLP DQVALPTDRP RPPAPSNLGG TARLTLDGDL HRQLHELARA HHASLFMVVH
     TALAALLSRL GAGPDVAVGT SVAGRGEQSL DGLVGMFVNT LVLRTDVHPD STGAALLEQV
     RRVDLEAFSH VEVPFEQLVD AINPTRSTAF HPLFQVALAL QNLQTPTLEL PGLEVSALDI
     ESPIAKFDLN FVLGERHDED GNPAGLDLEL GYAKDLFDAD TASRIGESFV RVLSGLAHDP
     RTPVGDLDLL GDDARLRLLA QSHGATRETV HSTLVGLLDE QVRATPSAPA VRWRDTALTY
     AEFDACANRL ARKLIADGVG PDAVVAVEIP RSLDLLVAVH AVVKAGGAYT PLDPGQPEQR
     NRDIVEQSGA SLVLTSSELL RQTGATRHGV RAIAPDALDP AEFGGEPIRA AERIAPLRPD
     NTAYVLFTSG STGRPKGVAV SHAAITAQLE WLREQYALGT ADTMLLKTPV TFDVSVWECF
     APLAAGARLV IADPDGHRDP EYLAEIVRTH GVTVVHFVPA MLAALTSGPG LTDMPALRHV
     LVGGEAVSPE TIDDFRASHP AEIDNTYGPT EAAVTTTFFA ARSDNSDTVP IGLPVWNTST
     LVLDDRLRPV PAGVAGELYL GGVQLARGYL GRPDLTAERF VADPFSTSGA RLYRTGDLVR
     WTAAGRLEYL GRTDFQVKVR GFRIELGEIV SALLRHEDVD QAVVVPHSDP HTGEHLVGYV
     VPRGAVALDC DAVLAEAAGS LPSYMVPSLL VPLTELPLTP NGKVDRNALP APVFAGKAEY
     TAPRTESERV VAAVFAELLG VSRVGVDDNF FELGGNSLSA TKLSTRIGVA TQTRIAIRDV
     FDAPTVAALA RRLDQHGPST AIAPLTAAVR PGRIPLSLAQ QRMWFLNQFE TSSPAYNLPA
     AVRLTGSLDT AALAAAIGDL IARHESLRTV FPDSRGGPHQ VILEPGDFTP DVAPVHVSET
     GLRADLQEFL LAGFDVSEAV PLRVKVYSLG PAEHVLALVV HHISADGASM EPLIRDVMIA
     YGSRAAGHPP TWAPLPVQYA DYALWQRTVL GSESEPGSLA AAQLDYWTRA LAGVPDQLYL
     PGDRGRPAVP THRGAATRFT LDAGTHRALT ELARAHGASL FMVAHAALSV LLGRLSTTAD
     IAVGTAVAGR GRVELDDIIG MFVNTLVLRT TLDPGASFVA LLAQTRTVDL EAFAHADLPF
     ERLVEVLSPV RSTSHHPLFQ VALGVQAVSA DGLELDGLSV TPLTLDASIA KFDLHFTLTE
     RLDDTAEPAG IDAELIYATD IFDESTAAGY ATRLRRIFEA VVADPQRPIG DIPVLGEDEH
     AALTPVRGAD PRPVQMLPEI LADAVAAAPD GLAVVFDGAG LTYRDLDERS NQLARLLVDR
     GVGPETSVAL ALPRSFESVV AVWAVAKTGA AFVPVDPGYP ADRIVHMVQD SGAMVGITVS
     AKRALLPDSI RWMLLDDPAL EVRCTHESRL PLTNRDRMRP ILSDQVAYVI YTSGSTGRPK
     GVAVTHRGLM NLVTDERELL AVTSRSRTLH FASPSFDASV FEMLMALGAG ATMVIAPPTI
     YGGSELAELL AAERITHAFS TPAALASVDH HGLDELAVVV VAGDVCPPEL VARWAPGRRL
     VNAYGPSEAT IMSSITEPLR AGEPVTIGGP SRGVRALVLD GRLRPVPVGV PGELYVGGPS
     LARGYLGRPG LTAERFVADP YGEPGDLMYR TGDLVRWRED RVLDFVGRTD HQVKIRGFRI
     ELGEIDAALT AHPQIEYATT IGYEHPNGET SLVAYVLPFT GEDVDRVEVA NFVGRTLPAY
     MVPASVTLLD ALPLTPAGKL DRSALPEPIF AAAATTFEAP RNPMEVIVAG IFADILALPE
     IGIHDSFFDL GGNSLLATQV VSRINAALDV HVGVREVFES PTVAALAARI TETTTHGARR
     PALTARARPE HIPLSLAQQR MWFINQFDTA SPAYNLPVAL RLSGEVDLRA MQIAIADLVG
     RHEALRTVYP DSGDGPHQVI VPAADAVPDL TPVTAHPDDV LERVLALVTT GFDVTSDVPL
     RARMYRVGAD DYVLVMVAHH ISGDGWSLAP LARDVMLAYT ARTEGHVPLW TPLPVQYADY
     SLWQRELLGD EADPESVAAE QIAYWTRTLD GLPDRLSLPT DRPRPAVASH RGAHVPFTID
     AATHRALLTL ARGRNTSLFM VMHTALAVLL ARLSNESDIA VGAPIAGRGE ESLDELVGMF
     VNTLVLRTHV DLASSFADSL NVARSTDLSA FAHSDIPFER LVDVLNPARS RSHHPLFQVA
     FSFQNLATAT LELPGLHVEG LDVPNTISTF DLHLTLSEKH DADGTPDVIE AQFTYATDLF
     DDTTVRAFAE RFTRILESVV RDPDLAVGAI DLLGGAERQS VIAEFNDTAV DLPPTTLADL
     FSAQAVRTPD YPAVFFEGTE LTYSEFDRRV DALAHRLIDS GVGPDTVVGL AMNRSIELLA
     GMYAVLRAGG AYLPIDLGHP ADRLAYVLET ARPVCVLTTS PDGFTAENVP VIEIDTLDLT
     GSPRGPVTDA HRRAPLRPEN TAYLIFTSGS TGRPKGVAVS HAAIANQLRW KQHEYPLDTT
     DAVVQKTPVT FDLSVWELFW PLMSGARLVI SRPDGHRDPA YLADLMRQQR VTTAHFVPSL
     LEAFIPDAGE QPTLRRVLCI GEALPVDTAA RFRSRFASVA LHNLYGPTEA AVSVTAWTHT
     DVDTDTVPIG GPEWNTQAFV LDARLNPVPV GVAGELYLAG DQLARGYVAR TDLTAERFVA
     NPFGAPGARL YRTGDVVRWR IRGTTGVLEY LERSDFQVKV RGFRIELGEI ESALIRSAGV
     GQAVVVAHRN PHTGTALVAY VVPEDGSTVD PTAVLADVGA AVPSYMVPAA LVVLAELPLT
     ANGKLDRKAL PAPDFASAAA EYRAPATPTE EIVAAVYADV LGVEQVGTAA NFFDLGGNSL
     VATRVVARLS ETLGRRVEIR SLFEAPAVGA LAALLDSTDA TAPTRPALTP AVRPELLPLS
     SAQQRMWFLN RFDPDSAVHN IPVAVRLSGV LDVDALQHAV ADVLHRHESL RTIYPDSADG
     PHQVILSTDR VGAETSVDAA DEAALPALIA DLVTTGFDVT AEVPVRVRIF RISATEHVLA
     VVVHHISGDG WSMAPMVRDV MAAYSARSAG TSPDWAPLPV QYADYALWQR DLLGDETDPD
     SVAARQLAFW TQTLAGAPDQ LDLPTDRPRP AVASYRGGTV DFTVPADLHG TVVGAARDAN
     ASVFMVVHSA LAVLLSRLAG SGDISIGTPV AGRGERELDD LIGMFVNTLV LRQHVDGGRT
     FAELLADVRE TDLAAFSHAD VPFERLVEVV NPSRSTGRHP LFQVMLTFQN LDQESLELGD
     LSVSGVDLDV DIAKFDLQLT LMEQFDSEGG PDGIAARLTY AADLFDEPSA HVFGQRFLQV
     LRAAVDGPDT AVGDLDVLGR GERKQIAGTN ATAHPVLAGT LASLFDTAVA ADPDRIAVVF
     DRDELTYANF DARVNRLARR LIEQGVGPES VVAVAMRRSI DLLVGIYAVV KAGGAYLPID
     PDHPVERTAY VLDTARPACV LVSGAGLADS GSVPVVDIAS EDLSRYGSAP VTDRDRLRPL
     TAANTAYVIF TSGSTGRPKG VAVTHGAIVN RLLWMQHEYA LTSADVVLQK TPVTFDVSVW
     ELFWPLQVGA SMVIAAPDGH RDPRYLTGLV QERHVTTMHF VPSMLSVFTA EPAVAVCDSL
     RLVFCSGEAL TPEQVSRFRG VSGAGLHNLY GPTEAAVDVT FWETGESDTH SVPIGRPVWN
     TQVHVLDARL HPVPNGVAGE LYLAGEQLAR GYLGRVDLTS DRFVANPFVA GGRMYRTGDL
     VRRRGDGALE YLGRTDFQVK LRGQRIELGE IESALEAHPD VVQAVVVVHR DERGDEALVA
     YLVGRRAAEW SDVRAHLSTR VPSYMIPARV VHLDTLPLSV NGKLDRKALP APEVRSAAAE
     YQPPRSAAER AVATVFGEVL EIDRVGATDS FFDLGGNSLI ATRVAAALGS ELGIDFPLQW
     MFSDPTPRSL GQRIQNAAID GVPGAGASLD VLLPIRTRGT AEPVFCVHPF IGLAWSYAGL
     SRELTEDRPI YGLQSPALTE AEPHPGTITD FADRYVREIR SIQPHGPYHL VGWSLGGVIA
     HEMAVQLQEA GEEVRLLGLL DSYVGLDRSV ENTATTADLL GGAGLDLPED GVLDELSPDG
     QFDAERAAAL LRVVGGPLAA LTAPELDRIY RNAQQAPDLI DAHRPRVFDG ELVFFTAALD
     DGFHVDPVTC WGPYVRGRID EHPVDATHWT MTTPDALAAI APHLARTQRR PRHAAPDPGR
     DTDPDDSANR PHSVR
//

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