(data stored in ACNUC7421 zone)

SWISSPROT: C1AT48_RHOOB

ID   C1AT48_RHOOB            Unreviewed;       472 AA.
AC   C1AT48;
DT   26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   26-MAY-2009, sequence version 1.
DT   07-JUN-2017, entry version 59.
DE   RecName: Full=Pyruvate kinase {ECO:0000256|RuleBase:RU000504};
DE            EC=2.7.1.40 {ECO:0000256|RuleBase:RU000504};
GN   Name=pyk {ECO:0000313|EMBL:BAH48980.1};
GN   OrderedLocusNames=ROP_07330 {ECO:0000313|EMBL:BAH48980.1};
OS   Rhodococcus opacus (strain B4).
OC   Bacteria; Actinobacteria; Corynebacteriales; Nocardiaceae;
OC   Rhodococcus.
OX   NCBI_TaxID=632772 {ECO:0000313|EMBL:BAH48980.1, ECO:0000313|Proteomes:UP000002212};
RN   [1] {ECO:0000313|EMBL:BAH48980.1, ECO:0000313|Proteomes:UP000002212}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=B4 {ECO:0000313|EMBL:BAH48980.1,
RC   ECO:0000313|Proteomes:UP000002212};
RA   Takarada H., Sekine M., Hosoyama A., Yamada R., Fujisawa T., Omata S.,
RA   Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S.;
RT   "Comparison of the complete genome sequences of Rhodococcus
RT   erythropolis PR4 and Rhodococcus opacus B4.";
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: ATP + pyruvate = ADP + phosphoenolpyruvate.
CC       {ECO:0000256|RuleBase:RU000504}.
CC   -!- PATHWAY: Carbohydrate degradation; glycolysis; pyruvate from D-
CC       glyceraldehyde 3-phosphate: step 5/5.
CC       {ECO:0000256|RuleBase:RU000504}.
CC   -!- SIMILARITY: Belongs to the pyruvate kinase family.
CC       {ECO:0000256|RuleBase:RU000504}.
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DR   EMBL; AP011115; BAH48980.1; -; Genomic_DNA.
DR   RefSeq; WP_012687979.1; NC_012522.1.
DR   ProteinModelPortal; C1AT48; -.
DR   STRING; 632772.ROP_07330; -.
DR   EnsemblBacteria; BAH48980; BAH48980; ROP_07330.
DR   KEGG; rop:ROP_07330; -.
DR   PATRIC; fig|632772.20.peg.796; -.
DR   eggNOG; ENOG4105CA9; Bacteria.
DR   eggNOG; COG0469; LUCA.
DR   HOGENOM; HOG000021558; -.
DR   KO; K00873; -.
DR   OMA; KHEAIEQ; -.
DR   OrthoDB; POG091H02AT; -.
DR   UniPathway; UPA00109; UER00188.
DR   Proteomes; UP000002212; Chromosome.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0030955; F:potassium ion binding; IEA:InterPro.
DR   GO; GO:0004743; F:pyruvate kinase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.1380.20; -; 1.
DR   InterPro; IPR001697; Pyr_Knase.
DR   InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR   InterPro; IPR011037; Pyrv_Knase-like_insert_dom.
DR   InterPro; IPR018209; Pyrv_Knase_AS.
DR   InterPro; IPR015793; Pyrv_Knase_brl.
DR   InterPro; IPR015795; Pyrv_Knase_C.
DR   PANTHER; PTHR11817; PTHR11817; 1.
DR   Pfam; PF00224; PK; 1.
DR   Pfam; PF02887; PK_C; 1.
DR   PRINTS; PR01050; PYRUVTKNASE.
DR   SUPFAM; SSF50800; SSF50800; 1.
DR   SUPFAM; SSF51621; SSF51621; 2.
DR   SUPFAM; SSF52935; SSF52935; 1.
DR   TIGRFAMs; TIGR01064; pyruv_kin; 1.
DR   PROSITE; PS00110; PYRUVATE_KINASE; 1.
PE   3: Inferred from homology;
DR   PRODOM; C1AT48.
DR   SWISS-2DPAGE; C1AT48.
KW   Complete proteome {ECO:0000313|Proteomes:UP000002212};
KW   Glycolysis {ECO:0000256|RuleBase:RU000504};
KW   Kinase {ECO:0000256|RuleBase:RU000504, ECO:0000313|EMBL:BAH48980.1};
KW   Magnesium {ECO:0000256|RuleBase:RU000504};
KW   Pyruvate {ECO:0000313|EMBL:BAH48980.1};
KW   Transferase {ECO:0000256|RuleBase:RU000504,
KW   ECO:0000313|EMBL:BAH48980.1}.
FT   DOMAIN        3    336       PK. {ECO:0000259|Pfam:PF00224}.
FT   DOMAIN      354    465       PK_C. {ECO:0000259|Pfam:PF02887}.
SQ   SEQUENCE   472 AA;  50835 MW;  8D68539DE8E571DD CRC64;
     MNRRTKIVCT LGPATATGDR IRELVESGMD VARLNFSHGE HADHEENYKR VRAASDATGK
     AVGVLADLQG PKIRLGRFAE GRTTWANGEE VRITVEECEG THDRVSTTYK QLAEDAKPGD
     RLLVDDGKVG LVVSGVEGND VICRVTEGGP VSNNKGVSLP GMNVSVPALS EKDIADLEFA
     LGLGVDFIAL SFVRSPADVE LVHAVMDRVG RRIPVIAKLE KPEAIDNLEA IVLAFDAVMV
     ARGDLGVELP LEQVPLVQKR AIQIARENAK PVIVATQMLE SMIENSRPTR AEASDVANAV
     LDGADAVMLS GETSVGKYVM ETVRTMARIV EAVENESTQV PPLTHVPRTK RGVISYAARD
     IGERLDAKAL VAFTQSGDTV RRLARLHTPL PLLAFTPLPE VRSQLSLTWG TETFIVDPVD
     STDAMVRQVD NALLGLGRYQ KGELVVIVAG SPPGTVGSTN LIHVHRIGEE DH
//

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