(data stored in ACNUC10821 zone)

SWISSPROT: C8U1D7_ECO10

ID   C8U1D7_ECO10            Unreviewed;       232 AA.
AC   C8U1D7;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   03-NOV-2009, sequence version 1.
DT   08-MAY-2019, entry version 63.
DE   RecName: Full=Thiamine import ATP-binding protein ThiQ {ECO:0000256|HAMAP-Rule:MF_01723};
DE            EC=3.6.3.- {ECO:0000256|HAMAP-Rule:MF_01723};
GN   Name=thiQ {ECO:0000256|HAMAP-Rule:MF_01723,
GN   ECO:0000313|EMBL:BAI28945.1};
GN   OrderedLocusNames=ECO103_0067 {ECO:0000313|EMBL:BAI28945.1};
OS   Escherichia coli O103:H2 (strain 12009 / EHEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=585395 {ECO:0000313|EMBL:BAI28945.1, ECO:0000313|Proteomes:UP000000959};
RN   [1] {ECO:0000313|EMBL:BAI28945.1, ECO:0000313|Proteomes:UP000000959}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=12009 / EHEC {ECO:0000313|Proteomes:UP000000959};
RX   PubMed=19815525; DOI=10.1073/pnas.0903585106;
RA   Ogura Y., Ooka T., Iguchi A., Toh H., Asadulghani M., Oshima K.,
RA   Kodama T., Abe H., Nakayama K., Kurokawa K., Tobe T., Hattori M.,
RA   Hayashi T.;
RT   "Comparative genomics reveal the mechanism of the parallel evolution
RT   of O157 and non-O157 enterohemorrhagic Escherichia coli.";
RL   Proc. Natl. Acad. Sci. U.S.A. 106:17939-17944(2009).
CC   -!- FUNCTION: Part of the ABC transporter complex ThiBPQ involved in
CC       thiamine import. Responsible for energy coupling to the transport
CC       system. {ECO:0000256|HAMAP-Rule:MF_01723}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins
CC       (ThiQ), two transmembrane proteins (ThiP) and a solute-binding
CC       protein (ThiB). {ECO:0000256|HAMAP-Rule:MF_01723}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000256|HAMAP-
CC       Rule:MF_01723}; Peripheral membrane protein {ECO:0000256|HAMAP-
CC       Rule:MF_01723}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. Thiamine
CC       importer (TC 3.A.1.19.1) family. {ECO:0000256|HAMAP-
CC       Rule:MF_01723}.
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DR   EMBL; AP010958; BAI28945.1; -; Genomic_DNA.
DR   RefSeq; WP_000916310.1; NC_013353.1.
DR   EnsemblBacteria; BAI28945; BAI28945; ECO103_0067.
DR   KEGG; eoh:ECO103_0067; -.
DR   KO; K02062; -.
DR   OMA; TSHYPSE; -.
DR   BioCyc; ECOL585395:ECO103_RS00340-MONOMER; -.
DR   Proteomes; UP000000959; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:InterPro.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0048502; F:thiamine-transporting ATPase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0071934; P:thiamine transmembrane transport; IEA:InterPro.
DR   GO; GO:0015888; P:thiamine transport; IEA:UniProtKB-UniRule.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like.
DR   InterPro; IPR017871; ABC_transporter_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005968; Thiamine_ABC_ThiQ.
DR   Pfam; PF00005; ABC_tran; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR01277; thiQ; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR   PROSITE; PS51288; THIQ; 1.
PE   3: Inferred from homology;
DR   PRODOM; C8U1D7.
DR   SWISS-2DPAGE; C8U1D7.
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_01723, ECO:0000256|PROSITE-
KW   ProRule:PRU00434};
KW   Cell inner membrane {ECO:0000256|HAMAP-Rule:MF_01723};
KW   Cell membrane {ECO:0000256|HAMAP-Rule:MF_01723};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000959};
KW   Hydrolase {ECO:0000256|HAMAP-Rule:MF_01723};
KW   Membrane {ECO:0000256|HAMAP-Rule:MF_01723};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_01723,
KW   ECO:0000256|PROSITE-ProRule:PRU00434};
KW   Transport {ECO:0000256|HAMAP-Rule:MF_01723}.
FT   DOMAIN        2    230       ABC transporter. {ECO:0000259|PROSITE:
FT                                PS50893}.
FT   NP_BIND      32     39       ATP. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00434}.
SQ   SEQUENCE   232 AA;  25040 MW;  82A049C7E1BA1423 CRC64;
     MLKLTDITWL YHHLPMRFSL TVERGEQVAI LGPSGAGKST LLNLIAGFLT PASGSLTIDS
     VDHTTTPPSR RPVSMLFQEN NLFSHLTVAQ NIGLGLNPGL KLNAAQQEKM HAIARQMGID
     NLMARLPGEL SGGQRQRVAL ARCLVREQPI LLLDEPFSAL DPALRQEMLT LVSTSCQQQK
     MTLLMVSHSV EDAARIATRS VVVADGRIAW QGKTNELLSG KASASALLGI TG
//

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