(data stored in ACNUC10821 zone)

SWISSPROT: C8U1E8_ECO10

ID   C8U1E8_ECO10            Unreviewed;       314 AA.
AC   C8U1E8;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   03-NOV-2009, sequence version 1.
DT   08-MAY-2019, entry version 62.
DE   SubName: Full=DNA-binding transcriptional activator LeuO {ECO:0000313|EMBL:BAI28956.1};
GN   Name=leuO {ECO:0000313|EMBL:BAI28956.1};
GN   OrderedLocusNames=ECO103_0078 {ECO:0000313|EMBL:BAI28956.1};
OS   Escherichia coli O103:H2 (strain 12009 / EHEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=585395 {ECO:0000313|EMBL:BAI28956.1, ECO:0000313|Proteomes:UP000000959};
RN   [1] {ECO:0000313|EMBL:BAI28956.1, ECO:0000313|Proteomes:UP000000959}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=12009 / EHEC {ECO:0000313|Proteomes:UP000000959};
RX   PubMed=19815525; DOI=10.1073/pnas.0903585106;
RA   Ogura Y., Ooka T., Iguchi A., Toh H., Asadulghani M., Oshima K.,
RA   Kodama T., Abe H., Nakayama K., Kurokawa K., Tobe T., Hattori M.,
RA   Hayashi T.;
RT   "Comparative genomics reveal the mechanism of the parallel evolution
RT   of O157 and non-O157 enterohemorrhagic Escherichia coli.";
RL   Proc. Natl. Acad. Sci. U.S.A. 106:17939-17944(2009).
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000256|SAAS:SAAS01096700}.
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DR   EMBL; AP010958; BAI28956.1; -; Genomic_DNA.
DR   RefSeq; WP_001297362.1; NC_013353.1.
DR   EnsemblBacteria; BAI28956; BAI28956; ECO103_0078.
DR   KEGG; eoh:ECO103_0078; -.
DR   HOGENOM; HOG000116777; -.
DR   KO; K05798; -.
DR   OMA; ICSPLDI; -.
DR   BioCyc; ECOL585395:ECO103_RS00395-MONOMER; -.
DR   Proteomes; UP000000959; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
DR   PRODOM; C8U1E8.
DR   SWISS-2DPAGE; C8U1E8.
KW   Complete proteome {ECO:0000313|Proteomes:UP000000959};
KW   DNA-binding {ECO:0000256|SAAS:SAAS01096662,
KW   ECO:0000313|EMBL:BAI28956.1};
KW   Transcription {ECO:0000256|SAAS:SAAS01096725};
KW   Transcription regulation {ECO:0000256|SAAS:SAAS01096646}.
FT   DOMAIN       22     79       HTH lysR-type. {ECO:0000259|PROSITE:
FT                                PS50931}.
SQ   SEQUENCE   314 AA;  35685 MW;  D4B1161D3A53EB8E CRC64;
     MPEVQTDHSE TAELSKPQLR MVDLNLLTVF DAVMQEQNIT RAAHVLGMSQ PAVSNAVARL
     KVMFNDELFV RYGRGIQPTA RAFQLFGSVR QALQLVQNEL PGSGFEPASS ERVFHLCVCS
     PLDSILTSQI YNHIEQIAPN IHVMFKSSLN QNTEHQLRYQ ETEFVISYED FHRPEFTSVP
     LFKDEMVLVA SKNHPTIKGP LLKHDVYNEQ HAAVSLDRFA SFSQPWYDTV DKQASIAYQG
     MAMMSVLSVV SQTHLVAIAP RWLAEEFAES LELQVLPLPL KQNSRTCYLS WHEAAGRDKG
     HQWMEEQLVS ICKR
//

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