(data stored in ACNUC10821 zone)

SWISSPROT: C8U256_ECO10

ID   C8U256_ECO10            Unreviewed;       255 AA.
AC   C8U256;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   03-NOV-2009, sequence version 1.
DT   08-MAY-2019, entry version 62.
DE   RecName: Full=Taurine import ATP-binding protein TauB {ECO:0000256|HAMAP-Rule:MF_01714};
DE            EC=7.6.2.7 {ECO:0000256|HAMAP-Rule:MF_01714};
GN   Name=tauB {ECO:0000256|HAMAP-Rule:MF_01714,
GN   ECO:0000313|EMBL:BAI29214.1};
GN   OrderedLocusNames=ECO103_0345 {ECO:0000313|EMBL:BAI29214.1};
OS   Escherichia coli O103:H2 (strain 12009 / EHEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=585395 {ECO:0000313|EMBL:BAI29214.1, ECO:0000313|Proteomes:UP000000959};
RN   [1] {ECO:0000313|EMBL:BAI29214.1, ECO:0000313|Proteomes:UP000000959}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=12009 / EHEC {ECO:0000313|Proteomes:UP000000959};
RX   PubMed=19815525; DOI=10.1073/pnas.0903585106;
RA   Ogura Y., Ooka T., Iguchi A., Toh H., Asadulghani M., Oshima K.,
RA   Kodama T., Abe H., Nakayama K., Kurokawa K., Tobe T., Hattori M.,
RA   Hayashi T.;
RT   "Comparative genomics reveal the mechanism of the parallel evolution
RT   of O157 and non-O157 enterohemorrhagic Escherichia coli.";
RL   Proc. Natl. Acad. Sci. U.S.A. 106:17939-17944(2009).
CC   -!- FUNCTION: Part of the ABC transporter complex TauABC involved in
CC       taurine import. Responsible for energy coupling to the transport
CC       system. {ECO:0000256|HAMAP-Rule:MF_01714}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O + taurine(out) = ADP + H(+) + phosphate +
CC         taurine(in); Xref=Rhea:RHEA:14613, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474,
CC         ChEBI:CHEBI:456216, ChEBI:CHEBI:507393; EC=7.6.2.7;
CC         Evidence={ECO:0000256|HAMAP-Rule:MF_01714};
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins
CC       (TauB), two transmembrane proteins (TauC) and a solute-binding
CC       protein (TauA). {ECO:0000256|HAMAP-Rule:MF_01714}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000256|HAMAP-
CC       Rule:MF_01714}; Peripheral membrane protein {ECO:0000256|HAMAP-
CC       Rule:MF_01714}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. Taurine
CC       importer (TC 3.A.1.17.1) family. {ECO:0000256|HAMAP-
CC       Rule:MF_01714}.
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DR   EMBL; AP010958; BAI29214.1; -; Genomic_DNA.
DR   RefSeq; WP_000939349.1; NC_013353.1.
DR   EnsemblBacteria; BAI29214; BAI29214; ECO103_0345.
DR   KEGG; eoh:ECO103_0345; -.
DR   KO; K10831; -.
DR   OMA; FENHWPK; -.
DR   BioCyc; ECOL585395:ECO103_RS01800-MONOMER; -.
DR   Proteomes; UP000000959; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0015411; F:taurine-transporting ATPase activity; IEA:UniProtKB-UniRule.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like.
DR   InterPro; IPR017871; ABC_transporter_CS.
DR   InterPro; IPR015859; ABC_transpr_TauD.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR   PROSITE; PS51250; TAUB; 1.
PE   3: Inferred from homology;
DR   PRODOM; C8U256.
DR   SWISS-2DPAGE; C8U256.
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_01714, ECO:0000256|PROSITE-
KW   ProRule:PRU00434};
KW   Cell inner membrane {ECO:0000256|HAMAP-Rule:MF_01714};
KW   Cell membrane {ECO:0000256|HAMAP-Rule:MF_01714};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000959};
KW   Membrane {ECO:0000256|HAMAP-Rule:MF_01714};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_01714,
KW   ECO:0000256|PROSITE-ProRule:PRU00434};
KW   Translocase {ECO:0000256|HAMAP-Rule:MF_01714};
KW   Transport {ECO:0000256|HAMAP-Rule:MF_01714}.
FT   DOMAIN        2    229       ABC transporter. {ECO:0000259|PROSITE:
FT                                PS50893}.
FT   DOMAIN      189    255       TAUB. {ECO:0000259|PROSITE:PS51250}.
FT   NP_BIND      34     41       ATP. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00434}.
SQ   SEQUENCE   255 AA;  28282 MW;  2704DF123E7F11D8 CRC64;
     MLQISHLYAD YGGKPALEDI NLTLESGELL VVLGPSGCGK TTLLNLIAGF VPYQHGSILL
     AGKRIEGPGA ERGVVFQNEG LLPWRNVQDN VAFGLQLAGI EKMQRLEIAH QMLKKVGLEG
     AEKRYIWQLS GGQRQRVGIA RALAANPQLL LLDEPFGALD AFTRDQMQTL LLKLWQETGK
     QVLLITHDIE EAVFMATELV LLSSGPGRVL ERLPLNFARR FVAGESSRSI KSDPQFIAMR
     EYVLSRVFEQ REAFS
//

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