(data stored in ACNUC10821 zone)

SWISSPROT: C8U2A0_ECO10

ID   C8U2A0_ECO10            Unreviewed;       139 AA.
AC   C8U2A0;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   03-NOV-2009, sequence version 1.
DT   08-MAY-2019, entry version 62.
DE   RecName: Full=Transcription antitermination protein NusB {ECO:0000256|HAMAP-Rule:MF_00073, ECO:0000256|SAAS:SAAS01079076};
DE   AltName: Full=Antitermination factor NusB {ECO:0000256|HAMAP-Rule:MF_00073};
GN   Name=nusB {ECO:0000256|HAMAP-Rule:MF_00073,
GN   ECO:0000313|EMBL:BAI29258.1};
GN   OrderedLocusNames=ECO103_0390 {ECO:0000313|EMBL:BAI29258.1};
OS   Escherichia coli O103:H2 (strain 12009 / EHEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=585395 {ECO:0000313|EMBL:BAI29258.1, ECO:0000313|Proteomes:UP000000959};
RN   [1] {ECO:0000313|EMBL:BAI29258.1, ECO:0000313|Proteomes:UP000000959}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=12009 / EHEC {ECO:0000313|Proteomes:UP000000959};
RX   PubMed=19815525; DOI=10.1073/pnas.0903585106;
RA   Ogura Y., Ooka T., Iguchi A., Toh H., Asadulghani M., Oshima K.,
RA   Kodama T., Abe H., Nakayama K., Kurokawa K., Tobe T., Hattori M.,
RA   Hayashi T.;
RT   "Comparative genomics reveal the mechanism of the parallel evolution
RT   of O157 and non-O157 enterohemorrhagic Escherichia coli.";
RL   Proc. Natl. Acad. Sci. U.S.A. 106:17939-17944(2009).
CC   -!- FUNCTION: Involved in transcription antitermination. Required for
CC       transcription of ribosomal RNA (rRNA) genes. Binds specifically to
CC       the boxA antiterminator sequence of the ribosomal RNA (rrn)
CC       operons. {ECO:0000256|HAMAP-Rule:MF_00073,
CC       ECO:0000256|SAAS:SAAS01079004}.
CC   -!- SIMILARITY: Belongs to the NusB family. {ECO:0000256|HAMAP-
CC       Rule:MF_00073, ECO:0000256|SAAS:SAAS00558782}.
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DR   EMBL; AP010958; BAI29258.1; -; Genomic_DNA.
DR   RefSeq; WP_000801125.1; NC_013353.1.
DR   SMR; C8U2A0; -.
DR   EnsemblBacteria; BAI29258; BAI29258; ECO103_0390.
DR   KEGG; eoh:ECO103_0390; -.
DR   HOGENOM; HOG000281868; -.
DR   KO; K03625; -.
DR   OMA; IPYKVVI; -.
DR   BioCyc; ECOL585395:ECO103_RS02045-MONOMER; -.
DR   Proteomes; UP000000959; Chromosome.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006353; P:DNA-templated transcription, termination; IEA:UniProtKB-UniRule.
DR   GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.940.10; -; 1.
DR   HAMAP; MF_00073; NusB; 1.
DR   InterPro; IPR035926; NusB-like_sf.
DR   InterPro; IPR011605; NusB_fam.
DR   InterPro; IPR006027; NusB_RsmB_TIM44.
DR   PANTHER; PTHR11078; PTHR11078; 1.
DR   Pfam; PF01029; NusB; 1.
DR   SUPFAM; SSF48013; SSF48013; 1.
DR   TIGRFAMs; TIGR01951; nusB; 1.
PE   3: Inferred from homology;
DR   PRODOM; C8U2A0.
DR   SWISS-2DPAGE; C8U2A0.
KW   Complete proteome {ECO:0000313|Proteomes:UP000000959};
KW   RNA-binding {ECO:0000256|HAMAP-Rule:MF_00073,
KW   ECO:0000256|SAAS:SAAS01090267};
KW   Transcription {ECO:0000256|HAMAP-Rule:MF_00073,
KW   ECO:0000256|SAAS:SAAS00057059};
KW   Transcription antitermination {ECO:0000256|HAMAP-Rule:MF_00073,
KW   ECO:0000256|SAAS:SAAS01078996};
KW   Transcription regulation {ECO:0000256|HAMAP-Rule:MF_00073,
KW   ECO:0000256|SAAS:SAAS00444733}.
FT   DOMAIN        7    131       NusB. {ECO:0000259|Pfam:PF01029}.
SQ   SEQUENCE   139 AA;  15689 MW;  0BB912103061243B CRC64;
     MKPAARRRAR ECAVQALYSW QLSQNDIADV EYQFLAEQDV KDVDVLYFRE LLAGVATNTA
     YLDGLMKPYL SRLLEELGQV EKAVLRIALY ELSKRSDVPY KVAINEAIEL AKSFGAEDSH
     KFVNGVLDKA APVIRPNKK
//

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