(data stored in ACNUC10821 zone)

SWISSPROT: C8U2B1_ECO10

ID   C8U2B1_ECO10            Unreviewed;       454 AA.
AC   C8U2B1;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   03-NOV-2009, sequence version 1.
DT   08-MAY-2019, entry version 50.
DE   SubName: Full=Predicted transporter {ECO:0000313|EMBL:BAI29269.1};
GN   Name=yajR {ECO:0000313|EMBL:BAI29269.1};
GN   OrderedLocusNames=ECO103_0401 {ECO:0000313|EMBL:BAI29269.1};
OS   Escherichia coli O103:H2 (strain 12009 / EHEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=585395 {ECO:0000313|EMBL:BAI29269.1, ECO:0000313|Proteomes:UP000000959};
RN   [1] {ECO:0000313|EMBL:BAI29269.1, ECO:0000313|Proteomes:UP000000959}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=12009 / EHEC {ECO:0000313|Proteomes:UP000000959};
RX   PubMed=19815525; DOI=10.1073/pnas.0903585106;
RA   Ogura Y., Ooka T., Iguchi A., Toh H., Asadulghani M., Oshima K.,
RA   Kodama T., Abe H., Nakayama K., Kurokawa K., Tobe T., Hattori M.,
RA   Hayashi T.;
RT   "Comparative genomics reveal the mechanism of the parallel evolution
RT   of O157 and non-O157 enterohemorrhagic Escherichia coli.";
RL   Proc. Natl. Acad. Sci. U.S.A. 106:17939-17944(2009).
RN   [2] {ECO:0000213|PDB:2RU9}
RP   STRUCTURE BY NMR OF 389-454.
RX   PubMed=24952155; DOI=10.1016/j.bbrc.2014.06.053;
RA   Jiang D., Zhao Y., Fan J., Liu X., Wu Y., Feng W., Zhang X.C.;
RT   "Atomic resolution structure of the E. coli YajR transporter YAM
RT   domain.";
RL   Biochem. Biophys. Res. Commun. 450:929-935(2014).
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DR   EMBL; AP010958; BAI29269.1; -; Genomic_DNA.
DR   RefSeq; WP_001000978.1; NC_013353.1.
DR   PDB; 2RU9; NMR; -; A=389-454.
DR   PDBsum; 2RU9; -.
DR   SMR; C8U2B1; -.
DR   EnsemblBacteria; BAI29269; BAI29269; ECO103_0401.
DR   KEGG; eoh:ECO103_0401; -.
DR   HOGENOM; HOG000264695; -.
DR   OMA; YADSFHS; -.
DR   BioCyc; ECOL585395:ECO103_RS02100-MONOMER; -.
DR   Proteomes; UP000000959; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   CDD; cd06174; MFS; 1.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   1: Evidence at protein level;
DR   PRODOM; C8U2B1.
DR   SWISS-2DPAGE; C8U2B1.
KW   3D-structure {ECO:0000213|PDB:2RU9};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000959};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     21     42       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     48     68       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     80     98       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    104    124       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    136    158       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    164    186       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    217    240       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    252    273       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    280    296       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    302    319       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    340    361       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    367    388       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN        1    393       MFS. {ECO:0000259|PROSITE:PS50850}.
SQ   SEQUENCE   454 AA;  48772 MW;  55743FCBC3B706BD CRC64;
     MNDYKMTPGE RRATWGLGTV FSLRMLGMFM VLPVLTTYGM ALQGASEALI GIAIGIYGLT
     QAVFQIPFGL LSDRIGRKPL IVGGLAVFAA GSVIAALSDS IWGIILGRAL QGSGAIAAAV
     MALLSDLTRE QNRTKAMAFI GVSFGITFAI AMVLGPIITH KLGLHALFWM IAILATTGIA
     LTIWVVPNSS THVLNRESGM VKGSFSKVLA EPRLLKLNFG IMCLHMLLMS TFVALPGQLA
     DAGFPAAEHW KVYLATMLIA FGSVVPFIIY AEVKRKMKQV FVFCVGLIVV AEIVLWNAQT
     QFWQLVVGVQ LFFVAFNLME ALLPSLISKE SPAGYKGTAM GVYSTSQFLG VAIGGSLGGW
     IDGMFDGQGV FLAGAMLAAV WLAVASTMKE PPYVSSLRIE IPADIAANEA LKVRLLETEG
     VKEVLIAEEE HSAYVKIDSK VTNRFEVEQA IRQA
//

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