(data stored in ACNUC10821 zone)

SWISSPROT: C8U2E9_ECO10

ID   C8U2E9_ECO10            Unreviewed;       397 AA.
AC   C8U2E9;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   03-NOV-2009, sequence version 1.
DT   08-MAY-2019, entry version 53.
DE   SubName: Full=Multidrug efflux system protein AcrA {ECO:0000313|EMBL:BAI29307.1};
GN   Name=acrA {ECO:0000313|EMBL:BAI29307.1};
GN   OrderedLocusNames=ECO103_0439 {ECO:0000313|EMBL:BAI29307.1};
OS   Escherichia coli O103:H2 (strain 12009 / EHEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=585395 {ECO:0000313|EMBL:BAI29307.1, ECO:0000313|Proteomes:UP000000959};
RN   [1] {ECO:0000313|EMBL:BAI29307.1, ECO:0000313|Proteomes:UP000000959}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=12009 / EHEC {ECO:0000313|Proteomes:UP000000959};
RX   PubMed=19815525; DOI=10.1073/pnas.0903585106;
RA   Ogura Y., Ooka T., Iguchi A., Toh H., Asadulghani M., Oshima K.,
RA   Kodama T., Abe H., Nakayama K., Kurokawa K., Tobe T., Hattori M.,
RA   Hayashi T.;
RT   "Comparative genomics reveal the mechanism of the parallel evolution
RT   of O157 and non-O157 enterohemorrhagic Escherichia coli.";
RL   Proc. Natl. Acad. Sci. U.S.A. 106:17939-17944(2009).
CC   -!- SIMILARITY: Belongs to the membrane fusion protein (MFP)
CC       (TC 8.A.1) family. {ECO:0000256|SAAS:SAAS00568556}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; AP010958; BAI29307.1; -; Genomic_DNA.
DR   RefSeq; WP_001295324.1; NC_013353.1.
DR   SMR; C8U2E9; -.
DR   EnsemblBacteria; BAI29307; BAI29307; ECO103_0439.
DR   KEGG; eoh:ECO103_0439; -.
DR   HOGENOM; HOG000158247; -.
DR   KO; K03585; -.
DR   OMA; QLTVKRY; -.
DR   BioCyc; ECOL585395:ECO103_RS02295-MONOMER; -.
DR   Proteomes; UP000000959; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   InterPro; IPR032317; HlyD_D23.
DR   InterPro; IPR006143; RND_pump_MFP.
DR   Pfam; PF00529; HlyD; 1.
DR   Pfam; PF16576; HlyD_D23; 1.
DR   TIGRFAMs; TIGR01730; RND_mfp; 1.
PE   3: Inferred from homology;
DR   PRODOM; C8U2E9.
DR   SWISS-2DPAGE; C8U2E9.
KW   Complete proteome {ECO:0000313|Proteomes:UP000000959};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     21       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        22    397       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002992425.
FT   DOMAIN       63    293       HlyD_D23. {ECO:0000259|Pfam:PF16576}.
SQ   SEQUENCE   397 AA;  42197 MW;  5B81DD5BC2B0A077 CRC64;
     MNKNRGFTPL AVVLMLSGSL ALTGCDDKQA QQGGQQMPAV GVVTVKTEPL QITTELPGRT
     SAYRIAEVRP QVSGIILKRN FKEGSDIEAG VSLYQIDPAT YQATYDSAKG DLAKAQAAAN
     IAQLTVNRYQ KLLGTQYISK QEYDQALADA QQANAAVTAA KAAVETARIN LAYTKVTSPI
     SGRIGKSNVT EGALVQNGQA TALATVQQLD PIYVDVTQSS NDFLRLKQEL ANGTLKQENG
     KAKVSLITSD GIKFPQDGTL EFSDVTVDQT TGSITLRAIF PNPDHTLLPG MFVRARLEEG
     LNPNAILVPQ QGVTRTPRGD ATVLVVGADD KVETRPIVAS QAIGDKWLVT EGLKAGDRVV
     ISGLQKVRPG VQVKAQEVTA DNNQQAASGA QPEQSKS
//

If you have problems or comments...

PBIL Back to PBIL home page