(data stored in ACNUC10821 zone)

SWISSPROT: C8U2V5_ECO10

ID   C8U2V5_ECO10            Unreviewed;       416 AA.
AC   C8U2V5;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   03-NOV-2009, sequence version 1.
DT   08-MAY-2019, entry version 54.
DE   RecName: Full=Enterobactin exporter EntS {ECO:0000256|HAMAP-Rule:MF_01436};
GN   Name=entS {ECO:0000256|HAMAP-Rule:MF_01436,
GN   ECO:0000313|EMBL:BAI29463.1};
GN   OrderedLocusNames=ECO103_0599 {ECO:0000313|EMBL:BAI29463.1};
OS   Escherichia coli O103:H2 (strain 12009 / EHEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=585395 {ECO:0000313|EMBL:BAI29463.1, ECO:0000313|Proteomes:UP000000959};
RN   [1] {ECO:0000313|EMBL:BAI29463.1, ECO:0000313|Proteomes:UP000000959}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=12009 / EHEC {ECO:0000313|Proteomes:UP000000959};
RX   PubMed=19815525; DOI=10.1073/pnas.0903585106;
RA   Ogura Y., Ooka T., Iguchi A., Toh H., Asadulghani M., Oshima K.,
RA   Kodama T., Abe H., Nakayama K., Kurokawa K., Tobe T., Hattori M.,
RA   Hayashi T.;
RT   "Comparative genomics reveal the mechanism of the parallel evolution
RT   of O157 and non-O157 enterohemorrhagic Escherichia coli.";
RL   Proc. Natl. Acad. Sci. U.S.A. 106:17939-17944(2009).
CC   -!- FUNCTION: Exports the siderophore enterobactin out of the cell.
CC       {ECO:0000256|HAMAP-Rule:MF_01436}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000256|HAMAP-
CC       Rule:MF_01436}; Multi-pass membrane protein {ECO:0000256|HAMAP-
CC       Rule:MF_01436}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. EntS
CC       (TC 2.A.1.38) family. {ECO:0000256|HAMAP-Rule:MF_01436}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; AP010958; BAI29463.1; -; Genomic_DNA.
DR   RefSeq; WP_001041789.1; NC_013353.1.
DR   EnsemblBacteria; BAI29463; BAI29463; ECO103_0599.
DR   KEGG; eoh:ECO103_0599; -.
DR   HOGENOM; HOG000183770; -.
DR   KO; K08225; -.
DR   OMA; RNGAYGW; -.
DR   BioCyc; ECOL585395:ECO103_RS03125-MONOMER; -.
DR   Proteomes; UP000000959; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0042931; F:enterobactin transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd06174; MFS; 1.
DR   HAMAP; MF_01436; MFS_EntS; 1.
DR   InterPro; IPR023722; Enterobactin_exp_EntS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR010290; TM_effector.
DR   Pfam; PF05977; MFS_3; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
DR   PRODOM; C8U2V5.
DR   SWISS-2DPAGE; C8U2V5.
KW   Cell inner membrane {ECO:0000256|HAMAP-Rule:MF_01436};
KW   Cell membrane {ECO:0000256|HAMAP-Rule:MF_01436};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000959};
KW   Membrane {ECO:0000256|HAMAP-Rule:MF_01436, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|HAMAP-Rule:MF_01436,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|HAMAP-Rule:MF_01436,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|HAMAP-Rule:MF_01436}.
FT   TOPO_DOM      1     21       Periplasmic. {ECO:0000256|HAMAP-Rule:
FT                                MF_01436}.
FT   TRANSMEM     21     42       Helical. {ECO:0000256|SAM:Phobius}.
FT   TOPO_DOM     43     55       Cytoplasmic. {ECO:0000256|HAMAP-Rule:
FT                                MF_01436}.
FT   TRANSMEM     54     74       Helical. {ECO:0000256|SAM:Phobius}.
FT   TOPO_DOM     77     95       Periplasmic. {ECO:0000256|HAMAP-Rule:
FT                                MF_01436}.
FT   TRANSMEM     86    105       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    111    135       Helical. {ECO:0000256|SAM:Phobius}.
FT   TOPO_DOM    117    118       Cytoplasmic. {ECO:0000256|HAMAP-Rule:
FT                                MF_01436}.
FT   TOPO_DOM    140    156       Periplasmic. {ECO:0000256|HAMAP-Rule:
FT                                MF_01436}.
FT   TRANSMEM    147    170       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    176    199       Helical. {ECO:0000256|SAM:Phobius}.
FT   TOPO_DOM    178    178       Cytoplasmic. {ECO:0000256|HAMAP-Rule:
FT                                MF_01436}.
FT   TOPO_DOM    200    218       Periplasmic. {ECO:0000256|HAMAP-Rule:
FT                                MF_01436}.
FT   TRANSMEM    219    246       Helical. {ECO:0000256|SAM:Phobius}.
FT   TOPO_DOM    240    256       Cytoplasmic. {ECO:0000256|HAMAP-Rule:
FT                                MF_01436}.
FT   TRANSMEM    258    276       Helical. {ECO:0000256|SAM:Phobius}.
FT   TOPO_DOM    278    300       Periplasmic. {ECO:0000256|HAMAP-Rule:
FT                                MF_01436}.
FT   TRANSMEM    288    305       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    311    336       Helical. {ECO:0000256|SAM:Phobius}.
FT   TOPO_DOM    322    356       Cytoplasmic. {ECO:0000256|HAMAP-Rule:
FT                                MF_01436}.
FT   TOPO_DOM    378    378       Periplasmic. {ECO:0000256|HAMAP-Rule:
FT                                MF_01436}.
FT   TRANSMEM    380    399       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       18    403       MFS. {ECO:0000259|PROSITE:PS50850}.
SQ   SEQUENCE   416 AA;  43301 MW;  64FCCF9AF986305A CRC64;
     MNKQSWLLNL SLLKTHPAFR AVFLARFISI VSLGLLGVAV PVQIQMMTHS TWQVGLSVTL
     TGGAMFVGLM VGGVLADRYE RKKVILLARG TCGIGFIGLC LNALLPEPSL LAIYLLGLWD
     GFFASLGVTA LLAATPALVG RENLMQAGAI TMLTVRLGSV ISPMIGGLLL ATGGVAWNYG
     LAAAGTFITL LPLLSLPALP PPPQPREHPL KSLLAGFRFL LASPLVGGIA LLGGLLTMAS
     AVRVLYPALA DNWQMSAAQI GFLYAAIPLG AAIGALTSGK LAHSARPGLL MLLSTLGSFL
     AIGLFGLMPM WILGVVCLAL FGWLSAVSSL LQYTMLQTQT PEAMLGRING LWTAQNVTGD
     AIGAALLGGL GAMMTPVASA SASGFGLLII GVLLLLVLVE LRRFRQTPPQ VTASDS
//

If you have problems or comments...

PBIL Back to PBIL home page