(data stored in ACNUC10821 zone)

SWISSPROT: C8U2Z9_ECO10

ID   C8U2Z9_ECO10            Unreviewed;       105 AA.
AC   C8U2Z9;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   03-NOV-2009, sequence version 1.
DT   08-MAY-2019, entry version 52.
DE   RecName: Full=Ribosomal silencing factor RsfS {ECO:0000256|HAMAP-Rule:MF_01477};
GN   Name=ybeB {ECO:0000313|EMBL:BAI29507.1};
GN   Synonyms=rsfS {ECO:0000256|HAMAP-Rule:MF_01477};
GN   OrderedLocusNames=ECO103_0644 {ECO:0000313|EMBL:BAI29507.1};
OS   Escherichia coli O103:H2 (strain 12009 / EHEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=585395 {ECO:0000313|EMBL:BAI29507.1, ECO:0000313|Proteomes:UP000000959};
RN   [1] {ECO:0000313|EMBL:BAI29507.1, ECO:0000313|Proteomes:UP000000959}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=12009 / EHEC {ECO:0000313|Proteomes:UP000000959};
RX   PubMed=19815525; DOI=10.1073/pnas.0903585106;
RA   Ogura Y., Ooka T., Iguchi A., Toh H., Asadulghani M., Oshima K.,
RA   Kodama T., Abe H., Nakayama K., Kurokawa K., Tobe T., Hattori M.,
RA   Hayashi T.;
RT   "Comparative genomics reveal the mechanism of the parallel evolution
RT   of O157 and non-O157 enterohemorrhagic Escherichia coli.";
RL   Proc. Natl. Acad. Sci. U.S.A. 106:17939-17944(2009).
CC   -!- FUNCTION: Functions as a ribosomal silencing factor. Interacts
CC       with ribosomal protein L14 (rplN), blocking formation of
CC       intersubunit bridge B8. Prevents association of the 30S and 50S
CC       ribosomal subunits and the formation of functional ribosomes, thus
CC       repressing translation. {ECO:0000256|HAMAP-Rule:MF_01477}.
CC   -!- SUBUNIT: Interacts with ribosomal protein L14 (rplN).
CC       {ECO:0000256|HAMAP-Rule:MF_01477}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01477}.
CC   -!- SIMILARITY: Belongs to the Iojap/RsfS family. {ECO:0000256|HAMAP-
CC       Rule:MF_01477}.
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DR   EMBL; AP010958; BAI29507.1; -; Genomic_DNA.
DR   RefSeq; WP_001161664.1; NC_013353.1.
DR   SMR; C8U2Z9; -.
DR   EnsemblBacteria; BAI29507; BAI29507; ECO103_0644.
DR   KEGG; eoh:ECO103_0644; -.
DR   HOGENOM; HOG000016051; -.
DR   KO; K09710; -.
DR   OMA; YNLEAFW; -.
DR   BioCyc; ECOL585395:ECO103_RS03360-MONOMER; -.
DR   Proteomes; UP000000959; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0042256; P:mature ribosome assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0090071; P:negative regulation of ribosome biogenesis; IEA:UniProtKB-UniRule.
DR   GO; GO:0017148; P:negative regulation of translation; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01477; Iojap_RsfS; 1.
DR   InterPro; IPR004394; Iojap/RsfS/C7orf30.
DR   PANTHER; PTHR21043; PTHR21043; 1.
DR   TIGRFAMs; TIGR00090; rsfS_iojap_ybeB; 1.
PE   3: Inferred from homology;
DR   PRODOM; C8U2Z9.
DR   SWISS-2DPAGE; C8U2Z9.
KW   Complete proteome {ECO:0000313|Proteomes:UP000000959};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01477};
KW   Repressor {ECO:0000256|HAMAP-Rule:MF_01477};
KW   Translation regulation {ECO:0000256|HAMAP-Rule:MF_01477}.
SQ   SEQUENCE   105 AA;  11582 MW;  7C1315607BD0B610 CRC64;
     MQGKALQDFV IDKIDDLKGQ DIIALDVQGK SSITDCMIIC TGTSSRHVMS IADHVVQESR
     AAGLLPLGVE GENSADWIVV DLGDVIVHVM QEESRRLYEL EKLWS
//

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