(data stored in ACNUC10043 zone)

SWISSPROT: D1YVF0_METPS

ID   D1YVF0_METPS            Unreviewed;       410 AA.
AC   D1YVF0;
DT   09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT   09-FEB-2010, sequence version 1.
DT   11-DEC-2019, entry version 53.
DE   RecName: Full=Translation initiation factor 2 subunit gamma {ECO:0000256|HAMAP-Rule:MF_00119};
DE   AltName: Full=aIF2-gamma {ECO:0000256|HAMAP-Rule:MF_00119};
DE   AltName: Full=eIF-2-gamma {ECO:0000256|HAMAP-Rule:MF_00119};
GN   Name=eif2g {ECO:0000256|HAMAP-Rule:MF_00119,
GN   ECO:0000313|EMBL:BAI60422.1};
GN   OrderedLocusNames=MCP_0350 {ECO:0000313|EMBL:BAI60422.1};
OS   Methanocella paludicola (strain DSM 17711 / JCM 13418 / NBRC 101707 /
OS   SANAE).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanocellales; Methanocellaceae; Methanocella.
OX   NCBI_TaxID=304371 {ECO:0000313|EMBL:BAI60422.1, ECO:0000313|Proteomes:UP000001882};
RN   [1] {ECO:0000313|Proteomes:UP000001882}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17711 / JCM 13418 / NBRC 101707 / SANAE
RC   {ECO:0000313|Proteomes:UP000001882};
RX   PubMed=21829548; DOI=10.1371/journal.pone.0022898;
RA   Sakai S., Takaki Y., Shimamura S., Sekine M., Tajima T., Kosugi H.,
RA   Ichikawa N., Tasumi E., Hiraki A.T., Shimizu A., Kato Y., Nishiko R.,
RA   Mori K., Fujita N., Imachi H., Takai K.;
RT   "Genome sequence of a mesophilic hydrogenotrophic methanogen Methanocella
RT   paludicola, the first cultivated representative of the order
RT   Methanocellales.";
RL   PLoS ONE 6:E22898-E22898(2011).
CC   -!- FUNCTION: eIF-2 functions in the early steps of protein synthesis by
CC       forming a ternary complex with GTP and initiator tRNA.
CC       {ECO:0000256|HAMAP-Rule:MF_00119}.
CC   -!- SUBUNIT: Heterotrimer composed of an alpha, a beta and a gamma chain.
CC       {ECO:0000256|HAMAP-Rule:MF_00119}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC       superfamily. Classic translation factor GTPase family. EIF2G subfamily.
CC       {ECO:0000256|HAMAP-Rule:MF_00119}.
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DR   EMBL; AP011532; BAI60422.1; -; Genomic_DNA.
DR   STRING; 304371.MCP_0350; -.
DR   EnsemblBacteria; BAI60422; BAI60422; MCP_0350.
DR   KEGG; mpd:MCP_0350; -.
DR   PATRIC; fig|304371.9.peg.359; -.
DR   eggNOG; arCOG01563; Archaea.
DR   eggNOG; COG5257; LUCA.
DR   HOGENOM; HOG000229292; -.
DR   KO; K03242; -.
DR   OMA; NIGMVGH; -.
DR   Proteomes; UP000001882; Chromosome.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR   CDD; cd15490; eIF2_gamma_III; 1.
DR   HAMAP; MF_00119; eIF_2_gamma; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   InterPro; IPR000795; TF_GTP-bd_dom.
DR   InterPro; IPR022424; TIF2_gsu.
DR   InterPro; IPR015256; TIF2_gsu_C.
DR   InterPro; IPR009000; Transl_B-barrel_sf.
DR   InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR   Pfam; PF09173; eIF2_C; 1.
DR   Pfam; PF00009; GTP_EFTU; 1.
DR   PRINTS; PR00315; ELONGATNFCT.
DR   SUPFAM; SSF50447; SSF50447; 1.
DR   SUPFAM; SSF50465; SSF50465; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR03680; eif2g_arch; 1.
DR   TIGRFAMs; TIGR00231; small_GTP; 1.
DR   PROSITE; PS51722; G_TR_2; 1.
PE   3: Inferred from homology;
DR   PRODOM; D1YVF0.
DR   SWISS-2DPAGE; D1YVF0.
KW   GTP-binding {ECO:0000256|HAMAP-Rule:MF_00119};
KW   Initiation factor {ECO:0000256|HAMAP-Rule:MF_00119,
KW   ECO:0000313|EMBL:BAI60422.1};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00119};
KW   Protein biosynthesis {ECO:0000256|HAMAP-Rule:MF_00119};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001882}.
FT   DOMAIN          3..201
FT                   /note="Tr-type G"
FT                   /evidence="ECO:0000259|PROSITE:PS51722"
FT   NP_BIND         12..19
FT                   /note="GTP"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_00119"
FT   NP_BIND         88..92
FT                   /note="GTP"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_00119"
FT   NP_BIND         144..147
FT                   /note="GTP"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_00119"
SQ   SEQUENCE   410 AA;  43705 MW;  02A89DC1B6FC6123 CRC64;
     MPQPVVNIGM VGHVDHGKTT LVSALSGVWT DTHSEELKRG ISIRLGYADC TFYKCTNCNE
     PECYTSKPEC AACGTKDLAP LRTVSFVDSP GHETLMATML SGAAIMDGAV LVIAANEPCP
     QPQTKEHLMA LDIIGIKNVV IAQNKIDIVS REEAIKHYNQ IKQFVKGTVA ENAPIVPVSA
     QQNINIDVLI KTIEETIPTP KHDLNKPGIM QVARSFDVNR PGTVPAKLNG GVLGGTISQG
     TFKVKDDIEI RPGRKVEHEG RTRWEPIATS VVKLVYGGDS VEEATPGGLL AVGTKLDPSM
     TKSDALAGQV AGKPGSLPPV WHKFVMKTQL LERVVGVADE AAMVKAISTS EPLMLSIGTS
     TTIGVVTSAR KDAAEVALKR PVCAEVGSRI AISRRIGARW RLIGVGVLSS
//

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