(data stored in ACNUC10043 zone)

SWISSPROT: D1YVH0_METPS

ID   D1YVH0_METPS            Unreviewed;       205 AA.
AC   D1YVH0;
DT   09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT   09-FEB-2010, sequence version 1.
DT   11-DEC-2019, entry version 47.
DE   RecName: Full=Translation initiation factor 2 subunit beta {ECO:0000256|HAMAP-Rule:MF_00232};
DE   AltName: Full=aIF2-beta {ECO:0000256|HAMAP-Rule:MF_00232};
DE   AltName: Full=eIF-2-beta {ECO:0000256|HAMAP-Rule:MF_00232};
GN   Name=eif2b {ECO:0000256|HAMAP-Rule:MF_00232,
GN   ECO:0000313|EMBL:BAI60442.1};
GN   OrderedLocusNames=MCP_0370 {ECO:0000313|EMBL:BAI60442.1};
OS   Methanocella paludicola (strain DSM 17711 / JCM 13418 / NBRC 101707 /
OS   SANAE).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanocellales; Methanocellaceae; Methanocella.
OX   NCBI_TaxID=304371 {ECO:0000313|EMBL:BAI60442.1, ECO:0000313|Proteomes:UP000001882};
RN   [1] {ECO:0000313|Proteomes:UP000001882}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17711 / JCM 13418 / NBRC 101707 / SANAE
RC   {ECO:0000313|Proteomes:UP000001882};
RX   PubMed=21829548; DOI=10.1371/journal.pone.0022898;
RA   Sakai S., Takaki Y., Shimamura S., Sekine M., Tajima T., Kosugi H.,
RA   Ichikawa N., Tasumi E., Hiraki A.T., Shimizu A., Kato Y., Nishiko R.,
RA   Mori K., Fujita N., Imachi H., Takai K.;
RT   "Genome sequence of a mesophilic hydrogenotrophic methanogen Methanocella
RT   paludicola, the first cultivated representative of the order
RT   Methanocellales.";
RL   PLoS ONE 6:E22898-E22898(2011).
CC   -!- FUNCTION: eIF-2 functions in the early steps of protein synthesis by
CC       forming a ternary complex with GTP and initiator tRNA.
CC       {ECO:0000256|HAMAP-Rule:MF_00232}.
CC   -!- SUBUNIT: Heterotrimer composed of an alpha, a beta and a gamma chain.
CC       {ECO:0000256|HAMAP-Rule:MF_00232}.
CC   -!- SIMILARITY: Belongs to the eIF-2-beta/eIF-5 family. {ECO:0000256|HAMAP-
CC       Rule:MF_00232}.
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DR   EMBL; AP011532; BAI60442.1; -; Genomic_DNA.
DR   STRING; 304371.MCP_0370; -.
DR   EnsemblBacteria; BAI60442; BAI60442; MCP_0370.
DR   KEGG; mpd:MCP_0370; -.
DR   eggNOG; arCOG01640; Archaea.
DR   eggNOG; COG1601; LUCA.
DR   eggNOG; COG3269; LUCA.
DR   HOGENOM; HOG000107197; -.
DR   KO; K03238; -.
DR   OMA; MLRCDAC; -.
DR   Proteomes; UP000001882; Chromosome.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00232; eIF_2_beta; 1.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR004458; TIF2_bsu_arc.
DR   InterPro; IPR002792; TRAM_dom.
DR   InterPro; IPR002735; Transl_init_fac_IF2/IF5.
DR   InterPro; IPR016189; Transl_init_fac_IF2/IF5_N.
DR   InterPro; IPR016190; Transl_init_fac_IF2/IF5_Zn-bd.
DR   Pfam; PF01873; eIF-5_eIF-2B; 1.
DR   Pfam; PF01938; TRAM; 1.
DR   SMART; SM00653; eIF2B_5; 1.
DR   SUPFAM; SSF100966; SSF100966; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   SUPFAM; SSF75689; SSF75689; 1.
DR   TIGRFAMs; TIGR00311; aIF-2beta; 1.
DR   PROSITE; PS50926; TRAM; 1.
PE   3: Inferred from homology;
DR   PRODOM; D1YVH0.
DR   SWISS-2DPAGE; D1YVH0.
KW   Initiation factor {ECO:0000256|HAMAP-Rule:MF_00232,
KW   ECO:0000313|EMBL:BAI60442.1};
KW   Protein biosynthesis {ECO:0000256|HAMAP-Rule:MF_00232};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001882}.
FT   DOMAIN          147..205
FT                   /note="TRAM"
FT                   /evidence="ECO:0000259|PROSITE:PS50926"
SQ   SEQUENCE   205 AA;  23038 MW;  7BF3C37C0F0FC17B CRC64;
     MVDYDALLNR AVSKTPQLEL TGERFQVPRP KVFAEGRTTV WDNYEEIREK LNRDTEHFGK
     FILRELGTAG KVEGNRMILQ GHFTSDAINA LVNDYVAEYV KCAECGRPDT KLIKYDRVTT
     LKCDACGAQR SIQKRRSRAI SEKPAAAIEE GKTYELKIET TGKKGDGIAK VDKFTIFVNG
     ARPGEIVKAK INKVDGTRAF AVREH
//

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