(data stored in ACNUC10043 zone)

SWISSPROT: D1YW99_METPS

ID   D1YW99_METPS            Unreviewed;       375 AA.
AC   D1YW99;
DT   09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT   09-FEB-2010, sequence version 1.
DT   11-DEC-2019, entry version 49.
DE   RecName: Full=ORC1-type DNA replication protein {ECO:0000256|HAMAP-Rule:MF_01407};
GN   Name=cdc6-2 {ECO:0000313|EMBL:BAI60721.1};
GN   OrderedLocusNames=MCP_0649 {ECO:0000313|EMBL:BAI60721.1};
OS   Methanocella paludicola (strain DSM 17711 / JCM 13418 / NBRC 101707 /
OS   SANAE).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanocellales; Methanocellaceae; Methanocella.
OX   NCBI_TaxID=304371 {ECO:0000313|EMBL:BAI60721.1, ECO:0000313|Proteomes:UP000001882};
RN   [1] {ECO:0000313|Proteomes:UP000001882}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17711 / JCM 13418 / NBRC 101707 / SANAE
RC   {ECO:0000313|Proteomes:UP000001882};
RX   PubMed=21829548; DOI=10.1371/journal.pone.0022898;
RA   Sakai S., Takaki Y., Shimamura S., Sekine M., Tajima T., Kosugi H.,
RA   Ichikawa N., Tasumi E., Hiraki A.T., Shimizu A., Kato Y., Nishiko R.,
RA   Mori K., Fujita N., Imachi H., Takai K.;
RT   "Genome sequence of a mesophilic hydrogenotrophic methanogen Methanocella
RT   paludicola, the first cultivated representative of the order
RT   Methanocellales.";
RL   PLoS ONE 6:E22898-E22898(2011).
CC   -!- FUNCTION: Involved in regulation of DNA replication.
CC       {ECO:0000256|HAMAP-Rule:MF_01407, ECO:0000256|SAAS:SAAS00552624}.
CC   -!- SIMILARITY: Belongs to the CDC6/cdc18 family. {ECO:0000256|HAMAP-
CC       Rule:MF_01407, ECO:0000256|SAAS:SAAS00991757}.
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DR   EMBL; AP011532; BAI60721.1; -; Genomic_DNA.
DR   STRING; 304371.MCP_0649; -.
DR   EnsemblBacteria; BAI60721; BAI60721; MCP_0649.
DR   KEGG; mpd:MCP_0649; -.
DR   PATRIC; fig|304371.9.peg.670; -.
DR   eggNOG; arCOG00467; Archaea.
DR   eggNOG; COG1474; LUCA.
DR   HOGENOM; HOG000230757; -.
DR   KO; K10725; -.
DR   OMA; YLFYENE; -.
DR   Proteomes; UP000001882; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.10; -; 1.
DR   HAMAP; MF_01407; ORC1_type_DNA_replic_protein; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR015163; Cdc6_C.
DR   InterPro; IPR014277; Orc1/Cdc6_arc.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF13401; AAA_22; 1.
DR   Pfam; PF09079; Cdc6_C; 1.
DR   SMART; SM01074; Cdc6_C; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR02928; TIGR02928; 1.
PE   3: Inferred from homology;
DR   PRODOM; D1YW99.
DR   SWISS-2DPAGE; D1YW99.
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_01407,
KW   ECO:0000256|SAAS:SAAS00991755}; Cell cycle {ECO:0000313|EMBL:BAI60721.1};
KW   Cell division {ECO:0000313|EMBL:BAI60721.1};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_01407,
KW   ECO:0000256|SAAS:SAAS00438025};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_01407,
KW   ECO:0000256|SAAS:SAAS00991756};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001882}.
FT   DOMAIN          300..373
FT                   /note="Cdc6_C"
FT                   /evidence="ECO:0000259|SMART:SM01074"
FT   NP_BIND         62..66
FT                   /note="ATP"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_01407"
FT   BINDING         206
FT                   /note="ATP"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_01407"
FT   BINDING         218
FT                   /note="ATP"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_01407"
SQ   SEQUENCE   375 AA;  42616 MW;  5CE6276BAC8859C5 CRC64;
     MTKDLLLWDQ TIFKEQEYFE LDFLPENLLH RDAQMRSLKF SVSPALRGST PLNAYCRGAP
     GTGKTSAVLK VFSELENATQ KVVPVYINCQ VDSTRYAIFA QIFKKLFGYP PPSSGISFKK
     LFSQIAKHLV EKKRVLIVAL DDFNYLMASK EADEVLYSLL RMHEVQPGAK VGVITILSDL
     TLDMVRDLTP QVQSVFLPEE IAFPQYSPEE IKDILKYRVR YGFMQGVISD ELIDIVTGYT
     ADTGDLRVGI NMLKRAGLNA ERRASRAISK EDIEKAYEGS RYIHLNYTIR NLKKEEKVLL
     KCIVASGKEE MMSGELYECF KEKTDLGYTS FYEMVNRLEG LKILSLNTTG KGTRGQSRLV
     SLMYDPGEVE KRIDV
//

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