(data stored in ACNUC7421 zone)

SWISSPROT: D4YWY8_SPHJU

ID   D4YWY8_SPHJU            Unreviewed;       418 AA.
AC   D4YWY8;
DT   15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT   15-JUN-2010, sequence version 1.
DT   08-MAY-2019, entry version 55.
DE   RecName: Full=Transcription termination factor Rho {ECO:0000256|HAMAP-Rule:MF_01884};
DE            EC=3.6.4.- {ECO:0000256|HAMAP-Rule:MF_01884};
DE   AltName: Full=ATP-dependent helicase Rho {ECO:0000256|HAMAP-Rule:MF_01884};
GN   Name=rho {ECO:0000256|HAMAP-Rule:MF_01884,
GN   ECO:0000313|EMBL:BAI94870.1};
GN   OrderedLocusNames=SJA_C1-00360 {ECO:0000313|EMBL:BAI94870.1};
OS   Sphingobium japonicum (strain DSM 16413 / CCM 7287 / MTCC 6362 / UT26
OS   / NBRC 101211 / UT26S).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingobium.
OX   NCBI_TaxID=452662 {ECO:0000313|EMBL:BAI94870.1, ECO:0000313|Proteomes:UP000007753};
RN   [1] {ECO:0000313|EMBL:BAI94870.1, ECO:0000313|Proteomes:UP000007753}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 16413 / CCM 7287 / MTCC 6362 / UT26 / NBRC 101211 / UT26S
RC   {ECO:0000313|Proteomes:UP000007753};
RX   PubMed=20817768; DOI=10.1128/JB.00961-10;
RA   Nagata Y., Ohtsubo Y., Endo R., Ichikawa N., Ankai A., Oguchi A.,
RA   Fukui S., Fujita N., Tsuda M.;
RT   "Complete genome sequence of the representative gamma-
RT   hexachlorocyclohexane-degrading bacterium Sphingobium japonicum
RT   UT26.";
RL   J. Bacteriol. 192:5852-5853(2010).
CC   -!- FUNCTION: Facilitates transcription termination by a mechanism
CC       that involves Rho binding to the nascent RNA, activation of Rho's
CC       RNA-dependent ATPase activity, and release of the mRNA from the
CC       DNA template. {ECO:0000256|HAMAP-Rule:MF_01884}.
CC   -!- SUBUNIT: Homohexamer. The homohexamer assembles into an open ring
CC       structure. {ECO:0000256|HAMAP-Rule:MF_01884}.
CC   -!- SIMILARITY: Belongs to the Rho family. {ECO:0000256|HAMAP-
CC       Rule:MF_01884}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|HAMAP-Rule:MF_01884}.
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DR   EMBL; AP010803; BAI94870.1; -; Genomic_DNA.
DR   RefSeq; WP_007689303.1; NC_014006.1.
DR   STRING; 452662.SJA_C1-00360; -.
DR   PRIDE; D4YWY8; -.
DR   EnsemblBacteria; BAI94870; BAI94870; SJA_C1-00360.
DR   GeneID; 29271746; -.
DR   KEGG; sjp:SJA_C1-00360; -.
DR   eggNOG; ENOG4105C4P; Bacteria.
DR   eggNOG; COG1158; LUCA.
DR   HOGENOM; HOG000076952; -.
DR   KO; K03628; -.
DR   OMA; DYNYLPG; -.
DR   Proteomes; UP000007753; Chromosome 1.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008186; F:RNA-dependent ATPase activity; IEA:InterPro.
DR   GO; GO:0006353; P:DNA-templated transcription, termination; IEA:UniProtKB-UniRule.
DR   CDD; cd04459; Rho_CSD; 1.
DR   CDD; cd01128; rho_factor; 1.
DR   HAMAP; MF_01884; Rho; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR000194; ATPase_F1/V1/A1_a/bsu_nucl-bd.
DR   InterPro; IPR011129; CSD.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR041703; Rho_factor_ATP-bd.
DR   InterPro; IPR011112; Rho_N.
DR   InterPro; IPR036269; Rho_N_sf.
DR   InterPro; IPR011113; Rho_RNA-bd.
DR   InterPro; IPR004665; Term_rho.
DR   PANTHER; PTHR46425; PTHR46425; 1.
DR   Pfam; PF00006; ATP-synt_ab; 1.
DR   Pfam; PF07498; Rho_N; 1.
DR   Pfam; PF07497; Rho_RNA_bind; 1.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00357; CSP; 1.
DR   SMART; SM00959; Rho_N; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   SUPFAM; SSF68912; SSF68912; 1.
DR   TIGRFAMs; TIGR00767; rho; 1.
PE   3: Inferred from homology;
DR   PRODOM; D4YWY8.
DR   SWISS-2DPAGE; D4YWY8.
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_01884};
KW   Complete proteome {ECO:0000313|Proteomes:UP000007753};
KW   Helicase {ECO:0000256|HAMAP-Rule:MF_01884};
KW   Hydrolase {ECO:0000256|HAMAP-Rule:MF_01884,
KW   ECO:0000256|SAAS:SAAS00446781};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_01884};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007753};
KW   RNA-binding {ECO:0000256|HAMAP-Rule:MF_01884};
KW   Transcription {ECO:0000256|HAMAP-Rule:MF_01884};
KW   Transcription regulation {ECO:0000256|HAMAP-Rule:MF_01884};
KW   Transcription termination {ECO:0000256|HAMAP-Rule:MF_01884}.
FT   DOMAIN        5     47       Rho_N. {ECO:0000259|SMART:SM00959}.
FT   DOMAIN       52    118       CSP. {ECO:0000259|SMART:SM00357}.
FT   DOMAIN      170    355       AAA. {ECO:0000259|SMART:SM00382}.
FT   NP_BIND     169    174       ATP. {ECO:0000256|HAMAP-Rule:MF_01884}.
FT   NP_BIND     181    186       ATP. {ECO:0000256|HAMAP-Rule:MF_01884}.
FT   BINDING     212    212       ATP. {ECO:0000256|HAMAP-Rule:MF_01884}.
SQ   SEQUENCE   418 AA;  46390 MW;  32FFF43662F14EE7 CRC64;
     MHLKDLKKKA PAELVTMAEE LGVEGASTLR KQDLMFAILK VEADNGEQIM GEGTIEVLPD
     GFGFLRSPEA NFLAGPDDIY VSPNQVRKFG LRTGDTVEGE IRAPKDGERY FALTKLISVN
     FDDPEVVRHR VNFDNLTPLY PTQKLTLDAT DPTVKDKSAR VIDIVSPQGK GQRALIVAPP
     RTGKTVLLQN IAKAITDNHP EVFLIVLLID ERPEEVTDMQ RSVKGEVVSS TFDEPAQRHV
     QVAEMVIEKA KRLVEHKKDV VILLDSITRL GRAYNTVVPS SGKVLTGGVD ANALQRPKRF
     FGAARNIEEG GSLSIIATAL IDTGSRMDEV IFEEFKGTGN SEIVLDRKVA DKRIFPALDV
     GKSGTRKEEL LVDKAKLSKM WVLRRILMQM GTVDAMEFLL DKMKDSKTNE DFFDSMNQ
//

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