(data stored in ACNUC7421 zone)

SWISSPROT: D4YX53_SPHJU

ID   D4YX53_SPHJU            Unreviewed;       339 AA.
AC   D4YX53;
DT   15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT   15-JUN-2010, sequence version 1.
DT   07-JUN-2017, entry version 43.
DE   RecName: Full=Holliday junction ATP-dependent DNA helicase RuvB {ECO:0000256|HAMAP-Rule:MF_00016};
DE            EC=3.6.4.12 {ECO:0000256|HAMAP-Rule:MF_00016};
GN   Name=ruvB {ECO:0000256|HAMAP-Rule:MF_00016,
GN   ECO:0000313|EMBL:BAI94935.1};
GN   OrderedLocusNames=SJA_C1-01010 {ECO:0000313|EMBL:BAI94935.1};
OS   Sphingobium japonicum (strain NBRC 101211 / UT26S).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingobium.
OX   NCBI_TaxID=452662 {ECO:0000313|EMBL:BAI94935.1, ECO:0000313|Proteomes:UP000007753};
RN   [1] {ECO:0000313|EMBL:BAI94935.1, ECO:0000313|Proteomes:UP000007753}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 101211 / UT26S {ECO:0000313|Proteomes:UP000007753};
RX   PubMed=20817768; DOI=10.1128/JB.00961-10;
RA   Nagata Y., Ohtsubo Y., Endo R., Ichikawa N., Ankai A., Oguchi A.,
RA   Fukui S., Fujita N., Tsuda M.;
RT   "Complete genome sequence of the representative gamma-
RT   hexachlorocyclohexane-degrading bacterium Sphingobium japonicum
RT   UT26.";
RL   J. Bacteriol. 192:5852-5853(2010).
CC   -!- FUNCTION: The RuvA-RuvB complex in the presence of ATP renatures
CC       cruciform structure in supercoiled DNA with palindromic sequence,
CC       indicating that it may promote strand exchange reactions in
CC       homologous recombination. RuvAB is a helicase that mediates the
CC       Holliday junction migration by localized denaturation and
CC       reannealing. {ECO:0000256|HAMAP-Rule:MF_00016}.
CC   -!- CATALYTIC ACTIVITY: ATP + H(2)O = ADP + phosphate.
CC       {ECO:0000256|HAMAP-Rule:MF_00016}.
CC   -!- SUBUNIT: Forms a complex with RuvA. {ECO:0000256|HAMAP-
CC       Rule:MF_00016}.
CC   -!- SIMILARITY: Belongs to the RuvB family. {ECO:0000256|HAMAP-
CC       Rule:MF_00016}.
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DR   EMBL; AP010803; BAI94935.1; -; Genomic_DNA.
DR   RefSeq; WP_007687344.1; NC_014006.1.
DR   STRING; 452662.SJA_C1-01010; -.
DR   EnsemblBacteria; BAI94935; BAI94935; SJA_C1-01010.
DR   GeneID; 29271813; -.
DR   KEGG; sjp:SJA_C1-01010; -.
DR   eggNOG; ENOG4105CKJ; Bacteria.
DR   eggNOG; COG2255; LUCA.
DR   HOGENOM; HOG000218623; -.
DR   KO; K03551; -.
DR   OMA; DEIHRMS; -.
DR   OrthoDB; POG091H00GH; -.
DR   Proteomes; UP000007753; Chromosome 1.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0009378; F:four-way junction helicase activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-HAMAP.
DR   GO; GO:0009432; P:SOS response; IEA:UniProtKB-HAMAP.
DR   Gene3D; 1.10.10.10; -; 1.
DR   HAMAP; MF_00016; DNA_helic_RuvB; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR004605; DNA_helicase_Holl-junc_RuvB.
DR   InterPro; IPR008823; DNA_helicase_Holl-junc_RuvB_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR008824; RuvB_N.
DR   InterPro; IPR011991; WHTH_DNA-bd_dom.
DR   PANTHER; PTHR42848; PTHR42848; 1.
DR   Pfam; PF05491; RuvB_C; 1.
DR   Pfam; PF05496; RuvB_N; 1.
DR   ProDom; PD005323; DNA_helicase_Holl-junc_RuvB_C; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00635; ruvB; 1.
PE   3: Inferred from homology;
DR   PRODOM; D4YX53.
DR   SWISS-2DPAGE; D4YX53.
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00016};
KW   Complete proteome {ECO:0000313|Proteomes:UP000007753};
KW   DNA damage {ECO:0000256|HAMAP-Rule:MF_00016};
KW   DNA recombination {ECO:0000256|HAMAP-Rule:MF_00016};
KW   DNA repair {ECO:0000256|HAMAP-Rule:MF_00016};
KW   Helicase {ECO:0000256|HAMAP-Rule:MF_00016,
KW   ECO:0000313|EMBL:BAI94935.1};
KW   Hydrolase {ECO:0000256|HAMAP-Rule:MF_00016};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00016};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007753};
KW   SOS response {ECO:0000256|HAMAP-Rule:MF_00016}.
FT   DOMAIN       51    178       AAA. {ECO:0000259|SMART:SM00382}.
FT   NP_BIND      59     66       ATP. {ECO:0000256|HAMAP-Rule:MF_00016}.
SQ   SEQUENCE   339 AA;  36855 MW;  D37FE3A42CEBDBFC CRC64;
     MSEDRLISST RRVEDADAAL RPKSLAEFIG QQAARENLRI FIEAAKGRGE ALDHVLFFGP
     PGLGKTTLAQ IVAREMGVGF RATSGPVIAK SGDLAALLTN LDEGDVLFVD EIHRLNPAVE
     EVLYPAMEDR ALDLMIGEGP SARSVRIDLP PFTLVGATTR QGLLTTPLRD RFGIPVRLQF
     YTVDELELVV RRAARLLDLA ITSDGAVEIA RRSRGTPRIA GRLLRRVRDF ANVAGAAAVD
     AKVADAALTR LEVDHLGLDL MDRRYLTMIA DIYRGGPVGV ETLAAGLSEA RDTIEEVIEP
     YLIQLGLIAR TARGRCLNAL GWKHLGLNPP SHVQDGLFD
//

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