(data stored in ACNUC7421 zone)

SWISSPROT: D4YX96_SPHJU

ID   D4YX96_SPHJU            Unreviewed;       705 AA.
AC   D4YX96;
DT   15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT   15-JUN-2010, sequence version 1.
DT   07-JUN-2017, entry version 48.
DE   SubName: Full=3,2-trans-enoyl-CoA isomerase {ECO:0000313|EMBL:BAI94978.1};
GN   Name=ehhadh3 {ECO:0000313|EMBL:BAI94978.1};
GN   OrderedLocusNames=SJA_C1-01440 {ECO:0000313|EMBL:BAI94978.1};
OS   Sphingobium japonicum (strain NBRC 101211 / UT26S).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingobium.
OX   NCBI_TaxID=452662 {ECO:0000313|EMBL:BAI94978.1, ECO:0000313|Proteomes:UP000007753};
RN   [1] {ECO:0000313|EMBL:BAI94978.1, ECO:0000313|Proteomes:UP000007753}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 101211 / UT26S {ECO:0000313|Proteomes:UP000007753};
RX   PubMed=20817768; DOI=10.1128/JB.00961-10;
RA   Nagata Y., Ohtsubo Y., Endo R., Ichikawa N., Ankai A., Oguchi A.,
RA   Fukui S., Fujita N., Tsuda M.;
RT   "Complete genome sequence of the representative gamma-
RT   hexachlorocyclohexane-degrading bacterium Sphingobium japonicum
RT   UT26.";
RL   J. Bacteriol. 192:5852-5853(2010).
CC   -!- CATALYTIC ACTIVITY: (S)-3-hydroxyacyl-CoA + NAD(+) = 3-oxoacyl-CoA
CC       + NADH. {ECO:0000256|SAAS:SAAS00379695}.
CC   -!- PATHWAY: Lipid metabolism; fatty acid beta-oxidation.
CC       {ECO:0000256|SAAS:SAAS00649747}.
CC   -!- SIMILARITY: Belongs to the enoyl-CoA hydratase/isomerase family.
CC       {ECO:0000256|RuleBase:RU003707}.
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DR   EMBL; AP010803; BAI94978.1; -; Genomic_DNA.
DR   RefSeq; WP_013038796.1; NC_014006.1.
DR   ProteinModelPortal; D4YX96; -.
DR   STRING; 452662.SJA_C1-01440; -.
DR   EnsemblBacteria; BAI94978; BAI94978; SJA_C1-01440.
DR   GeneID; 29271852; -.
DR   KEGG; sjp:SJA_C1-01440; -.
DR   eggNOG; ENOG4105DYT; Bacteria.
DR   eggNOG; COG1024; LUCA.
DR   eggNOG; COG1250; LUCA.
DR   HOGENOM; HOG000261347; -.
DR   KO; K07516; -.
DR   OMA; NIVEPGA; -.
DR   OrthoDB; POG091H0NDD; -.
DR   UniPathway; UPA00659; -.
DR   Proteomes; UP000007753; Chromosome 1.
DR   GO; GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; IEA:UniProtKB-UniPathway.
DR   Gene3D; 1.10.1040.10; -; 2.
DR   InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR   InterPro; IPR006108; 3HC_DH_C.
DR   InterPro; IPR008927; 6-PGluconate_DH_C-like.
DR   InterPro; IPR013328; 6PGD_dom_2.
DR   InterPro; IPR029045; ClpP/crotonase-like_dom.
DR   InterPro; IPR001753; Crotonase_core_superfam.
DR   InterPro; IPR018376; Enoyl-CoA_hyd/isom_CS.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   Pfam; PF00725; 3HCDH; 2.
DR   Pfam; PF02737; 3HCDH_N; 1.
DR   Pfam; PF00378; ECH_1; 1.
DR   SUPFAM; SSF48179; SSF48179; 2.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   SUPFAM; SSF52096; SSF52096; 1.
DR   PROSITE; PS00166; ENOYL_COA_HYDRATASE; 1.
PE   3: Inferred from homology;
DR   PRODOM; D4YX96.
DR   SWISS-2DPAGE; D4YX96.
KW   Complete proteome {ECO:0000313|Proteomes:UP000007753};
KW   Fatty acid metabolism {ECO:0000256|SAAS:SAAS00456821};
KW   Isomerase {ECO:0000313|EMBL:BAI94978.1};
KW   Lipid metabolism {ECO:0000256|SAAS:SAAS00456809};
KW   NAD {ECO:0000256|SAAS:SAAS00830857};
KW   Oxidoreductase {ECO:0000256|SAAS:SAAS00656508};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007753}.
FT   DOMAIN      296    470       3HCDH_N. {ECO:0000259|Pfam:PF02737}.
FT   DOMAIN      476    568       3HCDH. {ECO:0000259|Pfam:PF00725}.
FT   DOMAIN      603    689       3HCDH. {ECO:0000259|Pfam:PF00725}.
SQ   SEQUENCE   705 AA;  75354 MW;  19A84BFDA414B217 CRC64;
     MTSALAIHDG VAVIALDNPP VNGLSHALRC SIVDAVAEVN LNENIVAAVL IGAALPFSGG
     ADITEFGTPK SWEQPDLVAV IEAVEASAKP VVAAIAGVAL GGGLELALGC HARVALRNAR
     VGLPEVKLGL LPGAGGTQRL PRLVGVETAL DLITSGRLLP AGAAELKGMF AALVEPDEDL
     LEVASSIARS VARSGELPSI SSLPPAQPRP EIFDAARARL SGSGERYPAL PEIIAAVEAA
     TVLDFAAGME VEKAAFKRLI ETDVSKALRH GFLAERRASH VREIGADVGV RRLDTAAVIG
     AGLMGTGIAQ CLAAAGIEVT LLETSEQATV RSEKSVDDVL GRAVAKGRLT AKQAEAQKAL
     IRWTTDYGDL RNVDIAIEAV FESLEAKRAV FEELDRNLRP GAILASNTST LDLNAIAAFT
     QRPADVVGTH FFSPANVMRL LEVVRGDRTA PDVVKTAMQF GRRIGKVSVL SGVCDGFIGN
     RMVEEYFRQA MFLVEEGALP FEVDEALEEF GFSMGPFKVA DLAGLDIGWS IRKRRAQERP
     DMPYSPVLDG LCEQGRFGQK TKAGVYLYAD GRTAVRDPEV ERSIAAFSQS QNIARREISK
     SEIVDRCVLA LVNEGAKILE EGIAQRASDI DVVYLAGYGF PDFRGGPMFH ADSVGLDKVV
     ERMTVFERLQ TRDPAFWRPA PLLQHLVSTH SNFADWTNRS AMENL
//

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