(data stored in ACNUC7421 zone)

SWISSPROT: D4YXG3_SPHJU

ID   D4YXG3_SPHJU            Unreviewed;       654 AA.
AC   D4YXG3;
DT   15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT   15-JUN-2010, sequence version 1.
DT   07-JUN-2017, entry version 47.
DE   SubName: Full=3-hydroxyacyl-CoA dehydrogenase {ECO:0000313|EMBL:BAI95045.1};
GN   OrderedLocusNames=SJA_C1-02110 {ECO:0000313|EMBL:BAI95045.1};
OS   Sphingobium japonicum (strain NBRC 101211 / UT26S).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingobium.
OX   NCBI_TaxID=452662 {ECO:0000313|EMBL:BAI95045.1, ECO:0000313|Proteomes:UP000007753};
RN   [1] {ECO:0000313|EMBL:BAI95045.1, ECO:0000313|Proteomes:UP000007753}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 101211 / UT26S {ECO:0000313|Proteomes:UP000007753};
RX   PubMed=20817768; DOI=10.1128/JB.00961-10;
RA   Nagata Y., Ohtsubo Y., Endo R., Ichikawa N., Ankai A., Oguchi A.,
RA   Fukui S., Fujita N., Tsuda M.;
RT   "Complete genome sequence of the representative gamma-
RT   hexachlorocyclohexane-degrading bacterium Sphingobium japonicum
RT   UT26.";
RL   J. Bacteriol. 192:5852-5853(2010).
CC   -!- CATALYTIC ACTIVITY: (S)-3-hydroxyacyl-CoA + NAD(+) = 3-oxoacyl-CoA
CC       + NADH. {ECO:0000256|SAAS:SAAS00379695}.
CC   -!- PATHWAY: Lipid metabolism; fatty acid beta-oxidation.
CC       {ECO:0000256|SAAS:SAAS00649747}.
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DR   EMBL; AP010803; BAI95045.1; -; Genomic_DNA.
DR   RefSeq; WP_013038850.1; NC_014006.1.
DR   ProteinModelPortal; D4YXG3; -.
DR   STRING; 452662.SJA_C1-02110; -.
DR   EnsemblBacteria; BAI95045; BAI95045; SJA_C1-02110.
DR   GeneID; 29271915; -.
DR   KEGG; sjp:SJA_C1-02110; -.
DR   eggNOG; COG1250; LUCA.
DR   HOGENOM; HOG000261347; -.
DR   KO; K07516; -.
DR   OMA; DYKAKRQ; -.
DR   OrthoDB; POG091H0NDD; -.
DR   BioCyc; SJAP452662:GHEL-219-MONOMER; -.
DR   UniPathway; UPA00659; -.
DR   Proteomes; UP000007753; Chromosome 1.
DR   GO; GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; IEA:UniProtKB-UniPathway.
DR   Gene3D; 1.10.1040.10; -; 2.
DR   InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR   InterPro; IPR006108; 3HC_DH_C.
DR   InterPro; IPR008927; 6-PGluconate_DH_C-like.
DR   InterPro; IPR013328; 6PGD_dom_2.
DR   InterPro; IPR029045; ClpP/crotonase-like_dom.
DR   InterPro; IPR001753; Crotonase_core_superfam.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   Pfam; PF00725; 3HCDH; 1.
DR   Pfam; PF02737; 3HCDH_N; 1.
DR   Pfam; PF00378; ECH_1; 1.
DR   SUPFAM; SSF48179; SSF48179; 2.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   SUPFAM; SSF52096; SSF52096; 1.
PE   4: Predicted;
DR   PRODOM; D4YXG3.
DR   SWISS-2DPAGE; D4YXG3.
KW   Complete proteome {ECO:0000313|Proteomes:UP000007753};
KW   Fatty acid metabolism {ECO:0000256|SAAS:SAAS00456821};
KW   Lipid metabolism {ECO:0000256|SAAS:SAAS00456809};
KW   NAD {ECO:0000256|SAAS:SAAS00830857};
KW   Oxidoreductase {ECO:0000256|SAAS:SAAS00656508};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007753}.
FT   DOMAIN      300    476       3HCDH_N. {ECO:0000259|Pfam:PF02737}.
FT   DOMAIN      480    564       3HCDH. {ECO:0000259|Pfam:PF00725}.
SQ   SEQUENCE   654 AA;  68982 MW;  F949E7C898DDEA18 CRC64;
     MAFASEVASF SIREGIGECV VDAPPVNALG RDVRQALLDA VAEAAADPVV EALVIRCAGR
     TFFAGADIRE FGKPPLPPSL PEVVAAIEES AKPVIAAIHG TALGGGLEVA LGAHRRIAVS
     SARFGLPEVK LGLLPGAGGT QRLSRLVGVG KALAMIVGGD PISAEEALEA GLLDRKVADG
     TLIEAARQFA REAAGEGAPV RTRDLPVADP DRVDTVLDEY GNANPRRFGG QDAPAACVEV
     IRKGLHVPFD EALALERAAF TRLRDGAQSA ALRHVFFAER EVSKVAGIDA DTPRLPIDRV
     GVIGAGTMGR GIAMALLTAG LPVVLVEQRR EALDAGLAGV RDLIARAVKG GRMDRASADA
     ASARLTGSLS YDDLAEVDLV IEAAFETMEV KQVIFRALGG VAKPTAILAT NTSYLDVDAI
     AACTSRPEQV LGLHFFSPAN IMKLLEIVRG ARTSPQVLAT ALDLAKRLGK IAVVAGNAHG
     FIGNRMLMAR RLAAEAMALE GASPYAIDRV LVAFGMPMGP FRIGDLAGLD LGWTPETSTG
     STIRERLNER GRRGQKVGAG FYDYDDEGRA TPSPEVERII AELAADKAIP QRDWSDEAIL
     AGLLDPMIEE GRRIVAEGIA QRASDVDMVW VHGYGWPRWR GGPLYYADHR GEAG
//

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