(data stored in ACNUC7421 zone)

SWISSPROT: D4YY73_SPHJU

ID   D4YY73_SPHJU            Unreviewed;       203 AA.
AC   D4YY73;
DT   15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT   15-JUN-2010, sequence version 1.
DT   08-MAY-2019, entry version 42.
DE   RecName: Full=Acyl-homoserine-lactone synthase {ECO:0000256|RuleBase:RU361135};
DE            EC=2.3.1.184 {ECO:0000256|RuleBase:RU361135};
DE   AltName: Full=Autoinducer synthesis protein {ECO:0000256|RuleBase:RU361135};
GN   Name=luxI {ECO:0000313|EMBL:BAI95305.1};
GN   OrderedLocusNames=SJA_C1-04710 {ECO:0000313|EMBL:BAI95305.1};
OS   Sphingobium japonicum (strain DSM 16413 / CCM 7287 / MTCC 6362 / UT26
OS   / NBRC 101211 / UT26S).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingobium.
OX   NCBI_TaxID=452662 {ECO:0000313|EMBL:BAI95305.1, ECO:0000313|Proteomes:UP000007753};
RN   [1] {ECO:0000313|EMBL:BAI95305.1, ECO:0000313|Proteomes:UP000007753}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 16413 / CCM 7287 / MTCC 6362 / UT26 / NBRC 101211 / UT26S
RC   {ECO:0000313|Proteomes:UP000007753};
RX   PubMed=20817768; DOI=10.1128/JB.00961-10;
RA   Nagata Y., Ohtsubo Y., Endo R., Ichikawa N., Ankai A., Oguchi A.,
RA   Fukui S., Fujita N., Tsuda M.;
RT   "Complete genome sequence of the representative gamma-
RT   hexachlorocyclohexane-degrading bacterium Sphingobium japonicum
RT   UT26.";
RL   J. Bacteriol. 192:5852-5853(2010).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a fatty acyl-[ACP] + S-adenosyl-L-methionine = an N-acyl-
CC         L-homoserine lactone + H(+) + holo-[ACP] + S-methyl-5'-
CC         thioadenosine; Xref=Rhea:RHEA:10096, Rhea:RHEA-COMP:9685,
CC         Rhea:RHEA-COMP:14125, ChEBI:CHEBI:15378, ChEBI:CHEBI:17509,
CC         ChEBI:CHEBI:55474, ChEBI:CHEBI:59789, ChEBI:CHEBI:64479,
CC         ChEBI:CHEBI:138651; EC=2.3.1.184;
CC         Evidence={ECO:0000256|RuleBase:RU361135};
CC   -!- SIMILARITY: Belongs to the autoinducer synthase family.
CC       {ECO:0000256|PROSITE-ProRule:PRU00533,
CC       ECO:0000256|RuleBase:RU361135}.
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DR   EMBL; AP010803; BAI95305.1; -; Genomic_DNA.
DR   RefSeq; WP_007683387.1; NC_014006.1.
DR   STRING; 452662.SJA_C1-04710; -.
DR   EnsemblBacteria; BAI95305; BAI95305; SJA_C1-04710.
DR   GeneID; 35854663; -.
DR   KEGG; sjp:SJA_C1-04710; -.
DR   eggNOG; ENOG41063GI; Bacteria.
DR   eggNOG; COG3916; LUCA.
DR   HOGENOM; HOG000057753; -.
DR   OMA; GYQRMLP; -.
DR   Proteomes; UP000007753; Chromosome 1.
DR   GO; GO:0061579; F:N-acyl homoserine lactone synthase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0009372; P:quorum sensing; IEA:UniProtKB-UniRule.
DR   InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR   InterPro; IPR001690; Autoind_synthase.
DR   PANTHER; PTHR39322; PTHR39322; 1.
DR   Pfam; PF00765; Autoind_synth; 1.
DR   PRINTS; PR01549; AUTOINDCRSYN.
DR   SUPFAM; SSF55729; SSF55729; 1.
DR   PROSITE; PS51187; AUTOINDUCER_SYNTH_2; 1.
PE   3: Inferred from homology;
DR   PRODOM; D4YY73.
DR   SWISS-2DPAGE; D4YY73.
KW   Autoinducer synthesis {ECO:0000256|PROSITE-ProRule:PRU00533,
KW   ECO:0000256|RuleBase:RU361135};
KW   Complete proteome {ECO:0000313|Proteomes:UP000007753};
KW   Quorum sensing {ECO:0000256|PROSITE-ProRule:PRU00533,
KW   ECO:0000256|RuleBase:RU361135};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007753};
KW   S-adenosyl-L-methionine {ECO:0000256|RuleBase:RU361135};
KW   Transferase {ECO:0000256|RuleBase:RU361135}.
SQ   SEQUENCE   203 AA;  23081 MW;  825BFBC4AC985A27 CRC64;
     MHIGTGFSQA MEHRLFRSMF EERKRVFVDL LRWDVPVIAG RYEIDQFDND RAVYIVVTGD
     DGEHRASARL LPTTHEHILG TIFPDLCEEA PPRGSAILEI TRFCLARKLR ARERLELRNQ
     LVTALVEYAL ANQIHSFTGV AEWPWFQQIL GFGWTCRPLG LPTSEQGRSL VALQIDVDDR
     TREQLRASGI FRPVGLADLP AAA
//

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