(data stored in SCRATCH zone)

SWISSPROT: D4YYR8_SPHJU

ID   D4YYR8_SPHJU            Unreviewed;       133 AA.
AC   D4YYR8;
DT   15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT   15-JUN-2010, sequence version 1.
DT   08-MAY-2019, entry version 59.
DE   RecName: Full=Holo-[acyl-carrier-protein] synthase {ECO:0000256|HAMAP-Rule:MF_00101};
DE            Short=Holo-ACP synthase {ECO:0000256|HAMAP-Rule:MF_00101};
DE            EC=2.7.8.7 {ECO:0000256|HAMAP-Rule:MF_00101};
DE   AltName: Full=4'-phosphopantetheinyl transferase AcpS {ECO:0000256|HAMAP-Rule:MF_00101};
GN   Name=acpS {ECO:0000256|HAMAP-Rule:MF_00101,
GN   ECO:0000313|EMBL:BAI95500.1};
GN   OrderedLocusNames=SJA_C1-06660 {ECO:0000313|EMBL:BAI95500.1};
OS   Sphingobium japonicum (strain DSM 16413 / CCM 7287 / MTCC 6362 / UT26
OS   / NBRC 101211 / UT26S).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingobium.
OX   NCBI_TaxID=452662 {ECO:0000313|EMBL:BAI95500.1, ECO:0000313|Proteomes:UP000007753};
RN   [1] {ECO:0000313|EMBL:BAI95500.1, ECO:0000313|Proteomes:UP000007753}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 16413 / CCM 7287 / MTCC 6362 / UT26 / NBRC 101211 / UT26S
RC   {ECO:0000313|Proteomes:UP000007753};
RX   PubMed=20817768; DOI=10.1128/JB.00961-10;
RA   Nagata Y., Ohtsubo Y., Endo R., Ichikawa N., Ankai A., Oguchi A.,
RA   Fukui S., Fujita N., Tsuda M.;
RT   "Complete genome sequence of the representative gamma-
RT   hexachlorocyclohexane-degrading bacterium Sphingobium japonicum
RT   UT26.";
RL   J. Bacteriol. 192:5852-5853(2010).
CC   -!- FUNCTION: Transfers the 4'-phosphopantetheine moiety from coenzyme
CC       A to a Ser of acyl-carrier-protein. {ECO:0000256|HAMAP-
CC       Rule:MF_00101, ECO:0000256|SAAS:SAAS01153667}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=apo-[ACP] + CoA = adenosine 3',5'-bisphosphate + H(+) +
CC         holo-[ACP]; Xref=Rhea:RHEA:12068, Rhea:RHEA-COMP:9685,
CC         Rhea:RHEA-COMP:9690, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999,
CC         ChEBI:CHEBI:57287, ChEBI:CHEBI:58343, ChEBI:CHEBI:64479;
CC         EC=2.7.8.7; Evidence={ECO:0000256|HAMAP-Rule:MF_00101,
CC         ECO:0000256|SAAS:SAAS01144854};
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000256|HAMAP-
CC         Rule:MF_00101, ECO:0000256|SAAS:SAAS01153678};
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00101,
CC       ECO:0000256|SAAS:SAAS01153709}.
CC   -!- SIMILARITY: Belongs to the P-Pant transferase superfamily. AcpS
CC       family. {ECO:0000256|HAMAP-Rule:MF_00101,
CC       ECO:0000256|SAAS:SAAS01153685}.
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DR   EMBL; AP010803; BAI95500.1; -; Genomic_DNA.
DR   RefSeq; WP_013039195.1; NC_014006.1.
DR   STRING; 452662.SJA_C1-06660; -.
DR   EnsemblBacteria; BAI95500; BAI95500; SJA_C1-06660.
DR   GeneID; 29272339; -.
DR   KEGG; sjp:SJA_C1-06660; -.
DR   eggNOG; ENOG4105KJV; Bacteria.
DR   eggNOG; COG0736; LUCA.
DR   HOGENOM; HOG000014316; -.
DR   KO; K00997; -.
DR   OMA; DERHYAV; -.
DR   Proteomes; UP000007753; Chromosome 1.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008897; F:holo-[acyl-carrier-protein] synthase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.90.470.20; -; 1.
DR   HAMAP; MF_00101; AcpS; 1.
DR   InterPro; IPR008278; 4-PPantetheinyl_Trfase_dom.
DR   InterPro; IPR037143; 4-PPantetheinyl_Trfase_dom_sf.
DR   InterPro; IPR002582; ACPS.
DR   InterPro; IPR004568; Ppantetheine-prot_Trfase_dom.
DR   Pfam; PF01648; ACPS; 1.
DR   ProDom; PD004282; PPantethiene-prot_Trfase; 1.
DR   SUPFAM; SSF56214; SSF56214; 1.
DR   TIGRFAMs; TIGR00516; acpS; 1.
DR   TIGRFAMs; TIGR00556; pantethn_trn; 1.
PE   3: Inferred from homology;
DR   PRODOM; D4YYR8.
DR   SWISS-2DPAGE; D4YYR8.
KW   Complete proteome {ECO:0000313|Proteomes:UP000007753};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00101,
KW   ECO:0000256|SAAS:SAAS01153712};
KW   Fatty acid biosynthesis {ECO:0000256|HAMAP-Rule:MF_00101,
KW   ECO:0000256|SAAS:SAAS00089117};
KW   Fatty acid metabolism {ECO:0000256|HAMAP-Rule:MF_00101,
KW   ECO:0000256|SAAS:SAAS00089144};
KW   Lipid biosynthesis {ECO:0000256|HAMAP-Rule:MF_00101,
KW   ECO:0000256|SAAS:SAAS00089157};
KW   Lipid metabolism {ECO:0000256|HAMAP-Rule:MF_00101,
KW   ECO:0000256|SAAS:SAAS00089094};
KW   Magnesium {ECO:0000256|HAMAP-Rule:MF_00101,
KW   ECO:0000256|SAAS:SAAS01077217};
KW   Metal-binding {ECO:0000256|HAMAP-Rule:MF_00101,
KW   ECO:0000256|SAAS:SAAS01077211};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007753};
KW   Transferase {ECO:0000256|HAMAP-Rule:MF_00101,
KW   ECO:0000256|SAAS:SAAS00071051, ECO:0000313|EMBL:BAI95500.1}.
FT   DOMAIN        4     97       ACPS. {ECO:0000259|Pfam:PF01648}.
FT   METAL         8      8       Magnesium. {ECO:0000256|HAMAP-Rule:
FT                                MF_00101}.
FT   METAL        58     58       Magnesium. {ECO:0000256|HAMAP-Rule:
FT                                MF_00101}.
SQ   SEQUENCE   133 AA;  14411 MW;  1130061724A683A3 CRC64;
     MIVGLGSDLC NIERIENSLD RFGERFEKRV FTDVEQAKAN RRPFTKAGTL AKRFAAKEAF
     SKAVGTGFKQ GVFMKDIGVV NGPSGAPTLH LTGGALARLE SLVPAGHRPV VHLTLTDDHP
     WAQAFVIIEA LPL
//

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