(data stored in ACNUC14238 zone)

EMBL: BK006937

ID   BK006937; SV 2; linear; genomic DNA; STD; FUN; 316620 BP.
XX
AC   BK006937;
XX
PR   Project:PRJNA43747;
XX
DT   08-JUN-2010 (Rel. 105, Created)
DT   08-OCT-2019 (Rel. 142, Last updated, Version 21)
XX
DE   TPA: Saccharomyces cerevisiae S288C chromosome III, complete sequence.
XX
KW   Third Party Data; TPA; TPA:inferential.
XX
OS   Saccharomyces cerevisiae S288C
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
XX
RN   [1]
RP   1-316620
RX   DOI; 10.1038/357038a0.
RX   PUBMED; 1574125.
RA   Oliver S.G., van der Aart Q.J., Agostoni-Carbone M.L., Aigle M.,
RA   Alberghina L., Alexandraki D., Antoine G., Anwar R., Ballesta J.P.,
RA   Benit P.et.al.;
RT   "The complete DNA sequence of yeast chromosome III";
RL   Nature 357(6373):38-46(1992).
XX
RN   [2]
RP   1-316620
RX   PUBMED; 8849441.
RA   Goffeau A., Barrell B.G., Bussey H., Davis R.W., Dujon B., Feldmann H.,
RA   Galibert F., Hoheisel J.D., Jacq C., Johnston M., Louis E.J., Mewes H.W.,
RA   Murakami Y., Philippsen P., Tettelin H., Oliver S.G.;
RT   "Life with 6000 genes";
RL   Science, e1252229 274(5287):0-546(1996).
XX
RN   [3]
RP   1-316620
RG   Saccharomyces Genome Database
RA   ;
RT   ;
RL   Submitted (11-DEC-2009) to the INSDC.
RL   Department of Genetics, Stanford University, Stanford, CA 94305-5120, USA
XX
RN   [4]
RC   Protein update by submitter
RP   1-316620
RG   Saccharomyces Genome Database
RA   ;
RT   ;
RL   Submitted (21-MAY-2010) to the INSDC.
RL   Department of Genetics, Stanford University, Stanford, CA 94305-5120, USA
XX
RN   [5]
RC   Protein update by submitter
RP   1-316620
RG   Saccharomyces Genome Database
RA   ;
RT   ;
RL   Submitted (27-MAY-2010) to the INSDC.
RL   Department of Genetics, Stanford University, Stanford, CA 94305-5120, USA
XX
RN   [6]
RC   Sequence update by submitter
RP   1-316620
RG   Saccharomyces Genome Database
RA   ;
RT   ;
RL   Submitted (12-APR-2011) to the INSDC.
RL   Department of Genetics, Stanford University, Stanford, CA 94305-5120, USA
XX
RN   [7]
RC   Protein update by submitter
RP   1-316620
RG   Saccharomyces Genome Database
RA   ;
RT   ;
RL   Submitted (16-JAN-2015) to the INSDC.
RL   Department of Genetics, Stanford University, Stanford, CA 94305-5120, USA
XX
DR   MD5; 54f4a74aa6392d9e19b82c38aa8ab345.
DR   Ensembl-Scaffolds; BK006937.2:1-316620; saccharomyces_cerevisiae.
DR   Ensembl-Scaffolds; III:1-316620; saccharomyces_cerevisiae.
DR   EnsemblGenomes-Gn; ENSRNA049601284.
DR   EnsemblGenomes-Gn; ENSRNA049601331.
DR   EnsemblGenomes-Gn; ENSRNA049601372.
DR   EnsemblGenomes-Gn; ENSRNA049601404.
DR   EnsemblGenomes-Gn; ENSRNA049601485.
DR   EnsemblGenomes-Gn; ENSRNA049601520.
DR   EnsemblGenomes-Gn; ENSRNA049601564.
DR   EnsemblGenomes-Gn; ENSRNA049601628.
DR   EnsemblGenomes-Gn; ENSRNA049601664.
DR   EnsemblGenomes-Gn; ENSRNA049651593.
DR   EnsemblGenomes-Gn; ENSRNA049651617.
DR   EnsemblGenomes-Gn; ENSRNA049651636.
DR   EnsemblGenomes-Gn; YCL022C.
DR   EnsemblGenomes-Gn; YCL074W.
DR   EnsemblGenomes-Gn; YCL075W.
DR   EnsemblGenomes-Gn; snR189.
DR   EnsemblGenomes-Gn; snR33.
DR   EnsemblGenomes-Gn; snR43.
DR   EnsemblGenomes-Gn; snR65.
DR   EnsemblGenomes-Gn; tE(UUC)C.
DR   EnsemblGenomes-Gn; tG(GCC)C.
DR   EnsemblGenomes-Gn; tK(CUU)C.
DR   EnsemblGenomes-Gn; tL(CAA)C.
DR   EnsemblGenomes-Gn; tM(CAU)C.
DR   EnsemblGenomes-Gn; tN(GUU)C.
DR   EnsemblGenomes-Gn; tP(AGG)C.
DR   EnsemblGenomes-Gn; tQ(UUG)C.
DR   EnsemblGenomes-Gn; tS(CGA)C.
DR   EnsemblGenomes-Gn; tT(AGU)C.
DR   EnsemblGenomes-Tr; YCL022C.
DR   EnsemblGenomes-Tr; YCL074W.
DR   EnsemblGenomes-Tr; YCL075W.
DR   EnsemblGenomes-Tr; snR189.
DR   EnsemblGenomes-Tr; snR33.
DR   EnsemblGenomes-Tr; snR43.
DR   EnsemblGenomes-Tr; snR65.
DR   EnsemblGenomes-Tr; tE(UUC)C.
DR   EnsemblGenomes-Tr; tG(GCC)C.
DR   EnsemblGenomes-Tr; tK(CUU)C.
DR   EnsemblGenomes-Tr; tL(CAA)C.
DR   EnsemblGenomes-Tr; tM(CAU)C.
DR   EnsemblGenomes-Tr; tN(GUU)C.
DR   EnsemblGenomes-Tr; tP(AGG)C.
DR   EnsemblGenomes-Tr; tQ(UUG)C.
DR   EnsemblGenomes-Tr; tS(CGA)C.
DR   EnsemblGenomes-Tr; tT(AGU)C.
DR   RFAM; RF00005; tRNA.
DR   RFAM; RF01204; snR65.
DR   RFAM; RF01243; snR33.
DR   RFAM; RF01250; snR189.
DR   RFAM; RF01256; snR43.
DR   StrainInfo; 725481; 0.
XX
CC   On Apr 18, 2011 this sequence version replaced BK006937.1.
CC   ##Genome-Annotation-Data-START##
CC   Annotation Provider :: SGD
CC   Annotation Status   :: Full Annotation
CC   Annotation Version  :: R64-2-1
CC   URL                 :: http://www.yeastgenome.org/
CC   ##Genome-Annotation-Data-END##
XX
AH   LOCAL_SPAN      PRIMARY_IDENTIFIER   PRIMARY_SPAN   COMP
AS   1-316620        X59720.2             1-316613
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..316620
FT                   /organism="Saccharomyces cerevisiae S288C"
FT                   /chromosome="III"
FT                   /strain="S288C"
FT                   /mol_type="genomic DNA"
FT                   /db_xref="taxon:559292"
FT   telomere        complement(1..1098)
FT                   /note="TEL03L; Telomeric region on the left arm of
FT                   Chromosome III; composed of an X element core sequence, X
FT                   element combinatorial repeats, and a terminal stretch of
FT                   telomeric repeats"
FT   rep_origin      989..1068
FT                   /note="ARS300; Autonomously Replicating Sequence"
FT   mobile_element  1179..4322
FT                   /mobile_element_type="retrotransposon:YCLWTy5-1"
FT                   /note="YCLWTy5-1; Ty5 element, LTR retrotransposon of the
FT                   Copia (Pseudoviridae) group; this is the only near-full
FT                   length Ty5 retrotransposon in S288C and it is
FT                   non-functional"
FT   repeat_region   1179..1429
FT                   /rpt_type=LONG_TERMINAL_REPEAT
FT                   /note="Ty5 LTR"
FT   gene            2126..2566
FT                   /pseudo
FT                   /locus_tag="YCL075W"
FT                   /note="Pseudogene: encodes fragment of Ty Pol protein"
FT   mRNA            2126..2566
FT                   /pseudo
FT                   /locus_tag="YCL075W"
FT   gene            2824..3750
FT                   /pseudo
FT                   /locus_tag="YCL074W"
FT                   /note="Pseudogene: encodes fragment of Ty Pol protein"
FT   mRNA            2824..3750
FT                   /pseudo
FT                   /locus_tag="YCL074W"
FT   repeat_region   4073..4322
FT                   /rpt_type=LONG_TERMINAL_REPEAT
FT                   /note="Ty5 LTR"
FT   gene            complement(6479..8326)
FT                   /gene="GEX1"
FT                   /locus_tag="YCL073C"
FT   mRNA            complement(6479..8326)
FT                   /gene="GEX1"
FT                   /locus_tag="YCL073C"
FT                   /product="glutathione exchanger"
FT   CDS_pept        complement(6479..8326)
FT                   /codon_start=1
FT                   /gene="GEX1"
FT                   /locus_tag="YCL073C"
FT                   /product="glutathione exchanger"
FT                   /note="Proton:glutathione antiporter; localized to the
FT                   vacuolar and plasma membranes; imports glutathione from the
FT                   vacuole and exports it through the plasma membrane; has a
FT                   role in resistance to oxidative stress and modulation of
FT                   the PKA pathway; GEX1 has a paralog, GEX2, that arose from
FT                   a segmental duplication"
FT                   /db_xref="GOA:P25596"
FT                   /db_xref="InterPro:IPR001411"
FT                   /db_xref="InterPro:IPR011701"
FT                   /db_xref="InterPro:IPR036259"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25596"
FT                   /experiment="EXISTENCE:direct assay:GO:0005774 vacuolar
FT                   membrane [PMID:21490148]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005886 plasma
FT                   membrane [PMID:21490148]"
FT                   /experiment="EXISTENCE:direct assay:GO:0071944 cell
FT                   periphery [PMID:26928762]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0015299
FT                   solute:proton antiporter activity [PMID:21490148]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0034775
FT                   glutathione transmembrane transport [PMID:21490148]"
FT                   /protein_id="DAA07418.1"
FT                   /translation="MSSSVVGASSNKKSGIRQSCEIIERERHSNDDTYSMTSTFFKLKE
FT                   NEIMSAQFDSLKYKILLISTAFVCGFGISLDYTLRSTYTGYATNSYSEHSLLSTVQVIN
FT                   AVVSVGSQVVYSRLSDHFGRLRLFLVATIFYIMGTIIQSQATRLTMYAAGSVFYNCGYV
FT                   GTNLLLTLILSDFSSLKWRMFYQYASYWPYIIIPWISGNIITAANPQKNWSWNIAMWAF
FT                   IYPLSALPIIFLILYMKYKSSKTAEWRSLKEQARKERTGGLFENLVFLFWKLDIVGILL
FT                   ITVSLGCILVPLTLANETSQKWHNSKIIATLVSGGCLFFIFLYWEAKFAKSPLLPFKLL
FT                   SDRGIWAPLGVTFFNFFTFFISCDYLYPVLLVSMKESSTSAARIVNLPDFVAATASPFY
FT                   SLLVAKTRKLKLSVIGGCAAWMVCMGLFYKYRGGSGSHEGVIAASVIMGLSGLLCSNSV
FT                   IVILQAMTTHSRMAVITGIQYTFSKLGAAIGASVSGAIWTQTMPNQLYKNLGNDTLAEI
FT                   AYASPYTFISDYPWGSPERDAVVESYRYVQRIIMTVGLACTVPFFAFTMFMRDPELIDK
FT                   ATHEEFTEDGLVVLPDEENIFSQIKALFRHNRSNKKLGC"
FT   gene            9706..11082
FT                   /gene="VBA3"
FT                   /locus_tag="YCL069W"
FT   mRNA            9706..11082
FT                   /gene="VBA3"
FT                   /locus_tag="YCL069W"
FT                   /product="basic amino acid transporter"
FT   CDS_pept        9706..11082
FT                   /codon_start=1
FT                   /gene="VBA3"
FT                   /locus_tag="YCL069W"
FT                   /product="basic amino acid transporter"
FT                   /note="Permease of basic amino acids in the vacuolar
FT                   membrane; VBA3 has a paralog, VBA5, that arose from a
FT                   segmental duplication"
FT                   /db_xref="GOA:P25594"
FT                   /db_xref="InterPro:IPR001411"
FT                   /db_xref="InterPro:IPR011701"
FT                   /db_xref="InterPro:IPR020846"
FT                   /db_xref="InterPro:IPR036259"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25594"
FT                   /experiment="EXISTENCE:direct assay:GO:0000329 fungal-type
FT                   vacuole membrane [PMID:15572352]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
FT                   reticulum [PMID:26928762]"
FT                   /experiment="EXISTENCE:direct assay:GO:0015174 basic amino
FT                   acid transmembrane transporter activity [PMID:15572352]"
FT                   /experiment="EXISTENCE:direct assay:GO:0055085
FT                   transmembrane transport [PMID:15572352]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0015174 basic
FT                   amino acid transmembrane transporter activity
FT                   [PMID:15572352]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0015802 basic
FT                   amino acid transport [PMID:15572352]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0055085
FT                   transmembrane transport [PMID:15572352]"
FT                   /protein_id="DAA07419.1"
FT                   /translation="MNMLIVGRVVASVGGSGLQTLCFVIGCTMVGERSRPLVISILSCA
FT                   FAVAAIVGPIIGGAFTTHVTWRWCFYINLPIGGLAIIMFLLTYKAENKGILQQIKDAIG
FT                   TISSFTFSKFRHQVNFKRLMNGIIFKFDFFGFALCSAGLVLFLLGLTFGGNKYSWNSGQ
FT                   VIAYLVLGVLLFIFSLVYDFFLFDKFNPEPDNISYRPLLLRRLVAKPAIIIINMVTFLL
FT                   CTGYNGQMIYSVQFFQLIFASSAWKAGLHLIPIVITNVIAAIASGVITKKLGLVKPLLI
FT                   FGGVLGVIGAGLMTLMTNTSTKSTQIGVLLLPGFSLGFALQASLMSAQLQITKDRPEAA
FT                   MDFIEVTAFNTFMKSLGTTLGGVLSTTVFSASFHNKVSRAHLEPYEGKTVDDMILYRLQ
FT                   NYDGSHSTIGNILSDSIKNVFWMDLGFYALGFLFCSFSSNKKLIIPKKDETPEDNLEDK
FT                   "
FT   misc_feature    11146..14849
FT                   /note="HML; Mating type cassette - left; unexpressed
FT                   complete copy of the mating-type genes, silenced by the
FT                   Sir2 histone deacetylase and its associated SIR1, SIR3 and
FT                   SIR4 proteins; mating-type switching involves replacement
FT                   of the Ya or Yalpha sequences present at the MAT locus with
FT                   either the a or alpha genes located at one of the HM loci
FT                   in a process stimulated by the HO endonuclease; sequence
FT                   replacement occurs by gene conversion, leaving the donor
FT                   unaltered"
FT   rep_origin      11146..11401
FT                   /note="ARS301; Inactive replication origin linked to the
FT                   silent mating type locus HML; functions as a
FT                   transcriptional silencer"
FT   gene            complement(11503..12285)
FT                   /locus_tag="YCL068C"
FT   mRNA            complement(11503..12285)
FT                   /locus_tag="YCL068C"
FT                   /product="hypothetical protein"
FT   CDS_pept        complement(11503..12285)
FT                   /codon_start=1
FT                   /locus_tag="YCL068C"
FT                   /product="hypothetical protein"
FT                   /db_xref="GOA:P25593"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25593"
FT                   /protein_id="DAA07420.1"
FT                   /translation="MFVLIDNVLAYLLEQDDLFVTARFAIQGQIVSRRVNKIHISNITD
FT                   VLLQQFISHTLPYNDNIVPKKILDSMRTAVRQLLEATACVSRECPLVKRSQDIKRARKR
FT                   LLSDWYRLGADANMDAVLLVVNSAWRFLAVWRPFVNSIQHATQELYQNIAHYLLHGNVN
FT                   IQRVTALLQLVMGQDDLLFSMDDVLQEVFRIQLYLNKMLPHNSHKWQKPSPFDSANLLL
FT                   NFRDWTTDNALLQELLLSYPTINKNKHKNHSVPRLIQV"
FT   gene            complement(12386..13018)
FT                   /gene="HMLALPHA2"
FT                   /gene_synonym="ALPHA2"
FT                   /locus_tag="YCL067C"
FT   mRNA            complement(12386..13018)
FT                   /gene="HMLALPHA2"
FT                   /gene_synonym="ALPHA2"
FT                   /locus_tag="YCL067C"
FT                   /product="homeodomain mating type protein alpha2"
FT   CDS_pept        complement(12386..13018)
FT                   /codon_start=1
FT                   /gene="HMLALPHA2"
FT                   /gene_synonym="ALPHA2"
FT                   /locus_tag="YCL067C"
FT                   /product="homeodomain mating type protein alpha2"
FT                   /note="Silenced copy of ALPHA2 at HML; homeobox-domain
FT                   protein that associates with Mcm1p in haploid cells to
FT                   repress a-specific gene expression and interacts with a1p
FT                   in diploid cells to repress haploid-specific gene
FT                   expression"
FT                   /db_xref="GOA:P0CY09"
FT                   /db_xref="InterPro:IPR001356"
FT                   /db_xref="InterPro:IPR009057"
FT                   /db_xref="UniProtKB/Swiss-Prot:P0CY09"
FT                   /protein_id="DAA07421.1"
FT                   /translation="MNKIPIKDLLNPQITDEFKSSILDINKKLFSICCNLPKLPESVTT
FT                   EEEVELRDILGFLSRANKNRKISDEEKKLLQTTSQLTTTITVLLKEMRSIENDRSNYQL
FT                   TQKNKSADGLVFNVVTQDMINKSTKPYRGHRFTKENVRILESWFAKNIENPYLDTKGLE
FT                   NLMKNTSLSRIQIKNWVSNRRRKEKTITIAPELADLLSGEPLAKKKE"
FT   gene            13282..13809
FT                   /gene="HMLALPHA1"
FT                   /gene_synonym="ALPHA1"
FT                   /locus_tag="YCL066W"
FT   mRNA            13282..13809
FT                   /gene="HMLALPHA1"
FT                   /gene_synonym="ALPHA1"
FT                   /locus_tag="YCL066W"
FT                   /product="transcriptional co-activator mating type protein
FT                   alpha"
FT   CDS_pept        13282..13809
FT                   /codon_start=1
FT                   /gene="HMLALPHA1"
FT                   /gene_synonym="ALPHA1"
FT                   /locus_tag="YCL066W"
FT                   /product="transcriptional co-activator mating type protein
FT                   alpha"
FT                   /note="Silenced copy of ALPHA1 at HML; ALPHA1 encodes a
FT                   transcriptional coactivator involved in the regulation of
FT                   mating-type alpha-specific gene expression"
FT                   /db_xref="GOA:P0CY07"
FT                   /db_xref="InterPro:IPR006856"
FT                   /db_xref="UniProtKB/Swiss-Prot:P0CY07"
FT                   /protein_id="DAA07519.1"
FT                   /translation="MFTSKPAFKIKNKASKSYRNTAVSKKLKEKRLAEHVRPSCFNIIR
FT                   PLKKDIQIPVPSSRFLNKIQIHRIASGSQNTQFRQFNKTSIKSSKKYLNSFMAFRAYYS
FT                   QFGSGVKQNVLSSLLAEEWHADKMQHGIWDYFAQQYNFINPGFGFVEWLTNNYAEVRGD
FT                   GYWEDVFVHLAL"
FT   rep_origin      14575..14849
FT                   /note="ARS302; Inactive replication origin linked to the
FT                   silent mating type locus HML; functions as a
FT                   transcriptional silencer"
FT   rep_origin      14871..15213
FT                   /note="ARS303; Autonomously Replicating Sequence on
FT                   Chromosome III; inactive as replication origin at native
FT                   locus near HML"
FT   rep_origin      15214..16274
FT                   /note="ARS320; Autonomously Replicating Sequence on
FT                   Chromosome III; inactive as replication origin at native
FT                   locus near HML"
FT   gene            complement(15798..16880)
FT                   /gene="CHA1"
FT                   /locus_tag="YCL064C"
FT   mRNA            complement(15798..16880)
FT                   /gene="CHA1"
FT                   /locus_tag="YCL064C"
FT                   /product="L-serine/L-threonine ammonia-lyase CHA1"
FT   CDS_pept        complement(15798..16880)
FT                   /codon_start=1
FT                   /gene="CHA1"
FT                   /locus_tag="YCL064C"
FT                   /product="L-serine/L-threonine ammonia-lyase CHA1"
FT                   /EC_number="4.3.1.17"
FT                   /EC_number="4.3.1.19"
FT                   /note="Catabolic L-serine (L-threonine) deaminase;
FT                   catalyzes the degradation of both L-serine and L-threonine;
FT                   required to use serine or threonine as the sole nitrogen
FT                   source, transcriptionally induced by serine and threonine"
FT                   /db_xref="GOA:P25379"
FT                   /db_xref="InterPro:IPR000634"
FT                   /db_xref="InterPro:IPR001926"
FT                   /db_xref="InterPro:IPR036052"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25379"
FT                   /experiment="EXISTENCE:direct assay:GO:0003941 L-serine
FT                   ammonia-lyase activity [PMID:7042346]"
FT                   /experiment="EXISTENCE:direct assay:GO:0004794 L-threonine
FT                   ammonia-lyase activity [PMID:7042346]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005739
FT                   mitochondrion [PMID:14562095|PMID:16823961]"
FT                   /experiment="EXISTENCE:direct assay:GO:0042645
FT                   mitochondrial nucleoid [PMID:15692048]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0006565
FT                   L-serine catabolic process [PMID:7042346]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0006567
FT                   threonine catabolic process [PMID:7042346]"
FT                   /protein_id="DAA07423.1"
FT                   /translation="MSIVYNKTPLLRQFFPGKASAQFFLKYECLQPSGSFKSRGIGNLI
FT                   MKSAIRIQKDGKRSPQVFASSGGNAGFAAATACQRLSLPCTVVVPTATKKRMVDKIRNT
FT                   GAQVIVSGAYWKEADTFLKTNVMNKIDSQVIEPIYVHPFDNPDIWEGHSSMIDEIVQDL
FT                   KSQHISVNKVKGIVCSVGGGGLYNGIIQGLERYGLADRIPIVGVETNGCHVFNTSLKIG
FT                   QPVQFKKITSIATSLGTAVISNQTFEYARKYNTRSVVIEDKDVIETCLKYTHQFNMVIE
FT                   PACGAALHLGYNTKILENALGSKLAADDIVIIIACGGSSNTIKDLEEALDSMRKKDTPV
FT                   IEVADNFIFPEKNIVNLKSA"
FT   gene            17290..18561
FT                   /gene="VAC17"
FT                   /gene_synonym="YCL062W"
FT                   /locus_tag="YCL063W"
FT   mRNA            17290..18561
FT                   /gene="VAC17"
FT                   /gene_synonym="YCL062W"
FT                   /locus_tag="YCL063W"
FT                   /product="Vac17p"
FT   CDS_pept        17290..18561
FT                   /codon_start=1
FT                   /gene="VAC17"
FT                   /gene_synonym="YCL062W"
FT                   /locus_tag="YCL063W"
FT                   /product="Vac17p"
FT                   /note="Phosphoprotein involved in vacuole inheritance;
FT                   degraded in late M phase of the cell cycle; acts as a
FT                   vacuole-specific receptor for myosin Myo2p; involved in
FT                   regulation of asymmetric inheritance of
FT                   aggregated/misfolded proteins and age reset"
FT                   /db_xref="GOA:P25591"
FT                   /db_xref="InterPro:IPR035293"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25591"
FT                   /experiment="EXISTENCE:direct assay:GO:0000329 fungal-type
FT                   vacuole membrane [PMID:12594460]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0000011
FT                   vacuole inheritance [PMID:12594460]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000011 vacuole
FT                   inheritance [PMID:12594460]"
FT                   /experiment="EXISTENCE:physical interaction:GO:0000011
FT                   vacuole inheritance [PMID:12594460]"
FT                   /experiment="EXISTENCE:physical interaction:GO:0043495
FT                   protein membrane anchor [PMID:12642614]"
FT                   /experiment="EXISTENCE:physical interaction:GO:0071563
FT                   Myo2p-Vac17p-Vac8p transport complex [PMID:12594460]"
FT                   /protein_id="DAA07424.1"
FT                   /translation="MATQALEDITERLLIRSQEAILQLDLWIQRQQRSSICQTTDQESL
FT                   DKLSQQYNQYMSQLNSLYVRSESVRDKLSKEQQRRLITEDNEHQRIEDLVREFQDITLR
FT                   LNELATVPNEAPNDSPQSQSTRSSLGSFQPRPLKIIERQRLCMVTPSKPPKKSVGFNPI
FT                   NEVDCPSKTNSLPCSPKKQPARNRTLRAAKSHDTGLNKSKKPSSSDTYESFFKNRQRLS
FT                   LTFFDEMDDEDFDSDQDTIILPNISTPPHVGVTAKGAEFEPLRRYNSHESILSNKPAPS
FT                   KSLNLGSFSASFFRPSNPTFGTSISNVQVNCHPTVAATMAPSRNGPRISSSKALLSSFI
FT                   ARSDTHTVKENNTNLKHASFMDKFNSSLSTISESFQSKRGRKNKGMNEERISNHNVAQE
FT                   QKNNMDISVSIEELQDALNTELLF"
FT   gene            complement(18816..22106)
FT                   /gene="MRC1"
FT                   /gene_synonym="YCL060C"
FT                   /locus_tag="YCL061C"
FT   mRNA            complement(18816..22106)
FT                   /gene="MRC1"
FT                   /gene_synonym="YCL060C"
FT                   /locus_tag="YCL061C"
FT                   /product="chromatin-modulating protein MRC1"
FT   CDS_pept        complement(18816..22106)
FT                   /codon_start=1
FT                   /gene="MRC1"
FT                   /gene_synonym="YCL060C"
FT                   /locus_tag="YCL061C"
FT                   /product="chromatin-modulating protein MRC1"
FT                   /note="S-phase checkpoint protein required for DNA
FT                   replication; couples DNA helicase and polymerase; interacts
FT                   with and stabilizes Pol2p at stalled replication forks
FT                   during stress, where it forms a pausing complex with Tof1p
FT                   and is phosphorylated by Mec1p; defines a novel S-phase
FT                   checkpoint with Hog1p that coordinates DNA replication and
FT                   transcription upon osmostress; protects uncapped telomeres;
FT                   Dia2p-dependent degradation mediates checkpoint recovery;
FT                   mammalian claspin homolog"
FT                   /db_xref="GOA:P25588"
FT                   /db_xref="InterPro:IPR018564"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25588"
FT                   /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
FT                   [PMID:14562095]"
FT                   /experiment="EXISTENCE:direct assay:GO:0031298 replication
FT                   fork protection complex [PMID:16531994]"
FT                   /experiment="EXISTENCE:direct assay:GO:0034399 nuclear
FT                   periphery [PMID:25817432]"
FT                   /experiment="EXISTENCE:direct assay:GO:0043596 nuclear
FT                   replication fork [PMID:16103218]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0006281 DNA
FT                   repair [PMID:16219777]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0007064
FT                   mitotic sister chromatid cohesion [PMID:17483413]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0048478
FT                   replication fork protection [PMID:18851837]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000076 DNA
FT                   replication checkpoint
FT                   [PMID:11331602|PMID:11715016|PMID:12944972]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000723 telomere
FT                   maintenance [PMID:17323081]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006260 DNA
FT                   replication [PMID:16137625]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006281 DNA
FT                   repair [PMID:16219777]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006348
FT                   chromatin silencing at telomere [PMID:11331602]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0007064 mitotic
FT                   sister chromatid cohesion [PMID:17483413]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0030466
FT                   chromatin silencing at silent mating-type cassette
FT                   [PMID:11331602]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0031573 intra-S
FT                   DNA damage checkpoint [PMID:11715016]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0033262
FT                   regulation of nuclear cell cycle DNA replication
FT                   [PMID:23178807]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0043570
FT                   maintenance of DNA repeat elements [PMID:18321795]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0048478
FT                   replication fork protection [PMID:18632578]"
FT                   /experiment="EXISTENCE:physical interaction:GO:0048478
FT                   replication fork protection [PMID:18851837]"
FT                   /protein_id="DAA07425.1"
FT                   /translation="MDDALHALSSLTAKKRTTTYKKVAVPILDENDNTNGNGPNDIDNP
FT                   PELTGNGFLFANATLNRVKNRLEGKKAPEQNHNNGKDRSENSLPTQLISNLYDGGEELE
FT                   KSEVKDNSYSEKNVSSSFTQTQRIPVSIQQDKVFNVPIHSVNDGKPTQLIKEDGLVNET
FT                   SQALKTPLTTGRPGATQRIDSSGATSQTQPIKSIEPQSQIITTSSNHSNALSPKIPIIP
FT                   TELIGTSPLFQSIQNRGPDTQMDVPPQTAHDEDKTQAIGIPQATHQEQKTQIDTVAQTL
FT                   QDEVPHTLKIREIQSELASEDSKREKARNVEYKKPQKPIPTKKFFSKESFLADFDDSSS
FT                   NEDDDIKLENAHPKPVQNDDELHENKSVELNLTDETRINEKRVPLLSSYANNLKREIDS
FT                   SKCITLDLDSDSDEYGDDDMDSIKLSKDESVLPISQLSKATILNLKARLSKQNQKLSQR
FT                   PNKSKDPKVDHNVLLNTLRKASRKQILDHQKEVIETKGLKLEDMAKEKEIVENLLEQEI
FT                   LRNKRIRQKEKRREKLEENDFQLNAHDSGSDSGSESSGFALSGNEIADYESSGSENDNR
FT                   RESDSEKEDDEIILKQKKSHHVKHIINESDSDTEVEAKPKEKADESLPKRIAINLGHYG
FT                   DNIGEDTDKFQETNVLDTQNIEEVMAERNTIENEVKDDVYVNEEADEAIRRQLIDKEKL
FT                   QLKQKEKEHEAKIKELKKRGVTNFFEMEAEESEDEWHGIGGADGEGSDDYDSDLEKMID
FT                   DYSKNNFNPHEIREMLAAENKEMDIKMINKILYDIKNGGFRNKRAKNSLELELSDDDED
FT                   DVLQQYRLKRRELMRKRRLEIGDDAKLVKNPKSSAFFESMVEDIIEYKNPFGAEEEYNL
FT                   DITSTATDLDTQDNSINVGDNTGNNEQKPVDQKNKKVIISEDFVQKSLSFLKSNNYEDF
FT                   ETDKELSRIQHGNDEAIEDLYTLKQNSSIKSFTNSQTDSTTSKTVNTIIDLEKRPEDED
FT                   EVENGDTSLVGVFKHPSIIKSFASRTDINDKFKEGNKTVKILKSYKTVGSSKASITYMG
FT                   KTRKLIAPKRKTEGSHRYHHDHHNKKMKMKTKTKSNKLFESGQDSFDN"
FT   gene            complement(22429..23379)
FT                   /gene="KRR1"
FT                   /locus_tag="YCL059C"
FT   mRNA            complement(22429..23379)
FT                   /gene="KRR1"
FT                   /locus_tag="YCL059C"
FT                   /product="ribosome biosynthesis protein KRR1"
FT   CDS_pept        complement(22429..23379)
FT                   /codon_start=1
FT                   /gene="KRR1"
FT                   /locus_tag="YCL059C"
FT                   /product="ribosome biosynthesis protein KRR1"
FT                   /note="Nucleolar protein required for rRNA synthesis and
FT                   ribosomal assembly; required for the synthesis of 18S rRNA
FT                   and for the assembly of 40S ribosomal subunit; essential
FT                   gene"
FT                   /db_xref="GOA:P25586"
FT                   /db_xref="InterPro:IPR004087"
FT                   /db_xref="InterPro:IPR024166"
FT                   /db_xref="InterPro:IPR036612"
FT                   /db_xref="InterPro:IPR041174"
FT                   /db_xref="PDB:4QMF"
FT                   /db_xref="PDB:5WLC"
FT                   /db_xref="PDB:5WYJ"
FT                   /db_xref="PDB:5WYK"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25586"
FT                   /experiment="EXISTENCE:direct assay:GO:0005730 nucleolus
FT                   [PMID:11027267|PMID:12150911]"
FT                   /experiment="EXISTENCE:direct assay:GO:0030686 90S
FT                   preribosome [PMID:12150911]"
FT                   /experiment="EXISTENCE:direct assay:GO:0030688 preribosome,
FT                   small subunit precursor [PMID:15167894]"
FT                   /experiment="EXISTENCE:direct assay:GO:0032040
FT                   small-subunit processome [PMID:15590835]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000447
FT                   endonucleolytic cleavage in ITS1 to separate SSU-rRNA from
FT                   5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript
FT                   (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:11027267]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006364 rRNA
FT                   processing [PMID:11996121]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0042274
FT                   ribosomal small subunit biogenesis [PMID:12150911]"
FT                   /protein_id="DAA07426.1"
FT                   /translation="MVSTHNRDKPWDTDDIDKWKIEEFKEEDNASGQPFAEESSFMTLF
FT                   PKYRESYLKTIWNDVTRALDKHNIACVLDLVEGSMTVKTTRKTYDPAIILKARDLIKLL
FT                   ARSVPFPQAVKILQDDMACDVIKIGNFVTNKERFVKRRQRLVGPNGNTLKALELLTKCY
FT                   ILVQGNTVSAMGPFKGLKEVRRVVEDCMKNIHPIYHIKELMIKRELAKRPELANEDWSR
FT                   FLPMFKKRNVARKKPKKIRNVEKKVYTPFPPAQLPRKVDLEIESGEYFLSKREKQMKKL
FT                   NEQKEKQMEREIERQEERAKDFIAPEEEAYKPNQN"
FT   gene            complement(23523..23981)
FT                   /gene="FYV5"
FT                   /gene_synonym="MDF1"
FT                   /locus_tag="YCL058C"
FT   mRNA            complement(23523..23981)
FT                   /gene="FYV5"
FT                   /gene_synonym="MDF1"
FT                   /locus_tag="YCL058C"
FT                   /product="Fyv5p"
FT   CDS_pept        complement(23523..23981)
FT                   /codon_start=1
FT                   /gene="FYV5"
FT                   /gene_synonym="MDF1"
FT                   /locus_tag="YCL058C"
FT                   /product="Fyv5p"
FT                   /note="Protein involved in regulation of the mating
FT                   pathway; binds with Matalpha2p to promoters of
FT                   haploid-specific genes; required for survival upon exposure
FT                   to K1 killer toxin; involved in ion homeostasis"
FT                   /db_xref="GOA:P25585"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25585"
FT                   /experiment="EXISTENCE:direct assay:GO:0005829 cytosol
FT                   [PMID:26928762]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000122 negative
FT                   regulation of transcription by RNA polymerase II
FT                   [PMID:26649943]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000750
FT                   pheromone-dependent signal transduction involved in
FT                   conjugation with cellular fusion [PMID:20195295]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006873 cellular
FT                   ion homeostasis [PMID:10234789]"
FT                   /protein_id="DAA33856.1"
FT                   /translation="MQYHSALYVYIYVTFTTIPYKEKPDIISICFSMLSFVFDFSVRIC
FT                   SRTLESFSWSLISSSAFKVVSAFSLAGSCVLASRSSVGIIVSLLLFNFSTCNFVLFLSA
FT                   VLIDLFFCTFLPTPTFLPTPFFFMLHLPIFSLLNALELLYLIIAGLHI"
FT   gene            23584..23925
FT                   /gene="ADF1"
FT                   /locus_tag="YCL058W-A"
FT   mRNA            23584..23925
FT                   /gene="ADF1"
FT                   /locus_tag="YCL058W-A"
FT                   /product="Adf1p"
FT   CDS_pept        23584..23925
FT                   /codon_start=1
FT                   /gene="ADF1"
FT                   /locus_tag="YCL058W-A"
FT                   /product="Adf1p"
FT                   /note="Transcriptional repressor encoded by the FYV5
FT                   antisense strand; negatively regulates transcription of
FT                   FYV5 by binding to the promoter on the sense strand"
FT                   /db_xref="EnsemblGenomes-Gn:YCL058W-A"
FT                   /db_xref="EnsemblGenomes-Tr:YCL058W-A"
FT                   /db_xref="GOA:Q2V2Q1"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q2V2Q1"
FT                   /experiment="EXISTENCE:direct assay:GO:0001012 RNA
FT                   polymerase II regulatory region DNA binding
FT                   [PMID:20195295]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
FT                   [PMID:20195295]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000122 negative
FT                   regulation of transcription by RNA polymerase II
FT                   [PMID:20195295]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000750
FT                   pheromone-dependent signal transduction involved in
FT                   conjugation with cellular fusion [PMID:20195295]"
FT                   /protein_id="DAA07427.1"
FT                   /translation="MGKCSMKKKGVGKNVGVGKKVQKKRSISTAERKRTKLQVEKLNKS
FT                   SETMIPTLLREASTQEPAKLKAETTLKAEELIKDQEKDSKVREQIRTEKSKTNDSMLKQ
FT                   IEMISGFSL"
FT   gene            complement(24032..24325)
FT                   /gene="MIC10"
FT                   /gene_synonym="MCS10"
FT                   /gene_synonym="MIO10"
FT                   /gene_synonym="MOS1"
FT                   /locus_tag="YCL057C-A"
FT   mRNA            complement(24032..24325)
FT                   /gene="MIC10"
FT                   /gene_synonym="MCS10"
FT                   /gene_synonym="MIO10"
FT                   /gene_synonym="MOS1"
FT                   /locus_tag="YCL057C-A"
FT                   /product="Mic10p"
FT   CDS_pept        complement(24032..24325)
FT                   /codon_start=1
FT                   /gene="MIC10"
FT                   /gene_synonym="MCS10"
FT                   /gene_synonym="MIO10"
FT                   /gene_synonym="MOS1"
FT                   /locus_tag="YCL057C-A"
FT                   /product="Mic10p"
FT                   /note="Conserved component of the MICOS complex; MICOS
FT                   (formerly MINOS or MitOS) is a mitochondrial inner membrane
FT                   complex that extends into the intermembrane space and has a
FT                   role in the maintenance of crista junctions, inner membrane
FT                   architecture, and formation of contact sites to the outer
FT                   membrane; forms a subcomplex with Mic12p and Mic27p whose
FT                   assembly and stability requires cardiolipin; homo-oligomers
FT                   cause membrane bending; ortholog of human MINOS1"
FT                   /db_xref="GOA:Q96VH5"
FT                   /db_xref="InterPro:IPR007512"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q96VH5"
FT                   /experiment="EXISTENCE:direct assay:GO:0005739
FT                   mitochondrion [PMID:16823961|PMID:24769239]"
FT                   /experiment="EXISTENCE:direct assay:GO:0044284
FT                   mitochondrial crista junction [PMID:22009199]"
FT                   /experiment="EXISTENCE:direct assay:GO:0061024 membrane
FT                   organization [PMID:25955211]"
FT                   /experiment="EXISTENCE:direct assay:GO:0061617 MICOS
FT                   complex [PMID:21944719|PMID:21987634|PMID:22009199]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0042407 cristae
FT                   formation [PMID:21944719|PMID:21987634|PMID:22009199]"
FT                   /protein_id="DAA07428.1"
FT                   /translation="MSEQAQTQQPAKSTPSKDSNKNGSSVSTILDTKWDIVLSNMLVKT
FT                   AMGFGVGVFTSVLFFKRRAFPVWLGIGFGVGRGYAEGDAIFRSSAGLRSSKV"
FT   gene            24768..26906
FT                   /gene="PRD1"
FT                   /locus_tag="YCL057W"
FT   mRNA            24768..26906
FT                   /gene="PRD1"
FT                   /locus_tag="YCL057W"
FT                   /product="metalloendopeptidase"
FT   CDS_pept        24768..26906
FT                   /codon_start=1
FT                   /gene="PRD1"
FT                   /locus_tag="YCL057W"
FT                   /product="metalloendopeptidase"
FT                   /EC_number="3.4.24.37"
FT                   /note="Zinc metalloendopeptidase; found in the cytoplasm
FT                   and intermembrane space of mitochondria; with Cym1p,
FT                   involved in degradation of mitochondrial proteins and of
FT                   presequence peptides cleaved from imported proteins;
FT                   protein abundance increases in response to DNA replication
FT                   stress"
FT                   /db_xref="GOA:P25375"
FT                   /db_xref="InterPro:IPR001567"
FT                   /db_xref="InterPro:IPR024077"
FT                   /db_xref="InterPro:IPR024079"
FT                   /db_xref="InterPro:IPR024080"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25375"
FT                   /experiment="EXISTENCE:direct assay:GO:0000324 fungal-type
FT                   vacuole [PMID:8218194]"
FT                   /experiment="EXISTENCE:direct assay:GO:0004222
FT                   metalloendopeptidase activity [PMID:8218194|PMID:8307027]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
FT                   [PMID:8307027|PMID:14562095|PMID:24390141]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005739
FT                   mitochondrion [PMID:16823961|PMID:24769239]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005758
FT                   mitochondrial intermembrane space [PMID:8307027]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005794 Golgi
FT                   apparatus [PMID:8218194]"
FT                   /experiment="EXISTENCE:direct assay:GO:0006508 proteolysis
FT                   [PMID:8307027]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0004222
FT                   metalloendopeptidase activity [PMID:8307027]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006508
FT                   proteolysis [PMID:8307027]"
FT                   /protein_id="DAA07429.1"
FT                   /translation="MRLLLCKNWFASPVISPLLYTRSLYSMANTTSFPIAPQAPPNWSF
FT                   TPSDISGKTNEIINNSNNFYDSMSKVESPSVSNFVEPFMKFENELGPIINQLTFLQHVS
FT                   SDKEIRDASVNSSMKLDELNIDLSLRHDIFLQFARVWQDVQSKADSVERETFKYVEKSY
FT                   KDYIHSGLELDEGNRLKIKEIKKKISVNSINFSKNLGEQKEYITFTKEQLEGVPDSILT
FT                   QFETIKSDKDSNETLYKVTFKYPDIFPVMKLASSAQTRKQAFLADQNKVPENEAILLDT
FT                   LKLRDELASLLGYDTYANYNLYDKMAEDSTTVMNFLNDLKDKLIPLGRKELQVLQDMKA
FT                   EDVKKLNQGADPNYYIWDHRYYDNKYLLENFNVDLEKISEYFPLEATITGMLEIYETLF
FT                   NLKFIETKDSQNKSVWHDDVKQIAVWNMDDPKSPNFVGWIYFDLHPRDGKYGHAANFGL
FT                   SSSFMIDDTTRSYPVTALVCNFSKSTKDKPSLLKHNEIVTFFHELGHGIHDLVGQNKES
FT                   RFNGPGSVPWDFVEAPSQMLEFWTWNKNELINLSSHYKTGEKIPESLINSLIKTKHVNG
FT                   ALFTLRQLHFGLFDMKVHTCKDLQNLSICDTWNQLRQDISLISNGGTLSKGYDSFGHIM
FT                   SDSYSAGYYGYLWAEVFATDMYHTKFAKDPLNAKNGIQYRDIVLARGGLYDINDNLKEF
FT                   LGREPSKDAFLKELGLQN"
FT   gene            complement(26925..27359)
FT                   /gene="PEX34"
FT                   /locus_tag="YCL056C"
FT   mRNA            complement(26925..27359)
FT                   /gene="PEX34"
FT                   /locus_tag="YCL056C"
FT                   /product="Pex34p"
FT   CDS_pept        complement(26925..27359)
FT                   /codon_start=1
FT                   /gene="PEX34"
FT                   /locus_tag="YCL056C"
FT                   /product="Pex34p"
FT                   /note="Protein that regulates peroxisome populations;
FT                   peroxisomal integral membrane protein; interacts with
FT                   Pex11p, Pex25p, and Pex27p to control both constitutive
FT                   peroxisome division and peroxisome morphology and abundance
FT                   during peroxisome proliferation"
FT                   /db_xref="GOA:P25584"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25584"
FT                   /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
FT                   [PMID:14562095]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005779 integral
FT                   component of peroxisomal membrane [PMID:21441307]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0007031
FT                   peroxisome organization [PMID:21441307]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0007031
FT                   peroxisome organization [PMID:21441307]"
FT                   /protein_id="DAA07430.1"
FT                   /translation="MVSKKNTAEISAKDIWENIWSGVSSLLDFFAVLENLGVVNDKLYV
FT                   SGLLRKVWLCYSCISVIKCVWKLIKLCKVKFKIDQRLDGEGNGLVKDKLINFKKKYNEH
FT                   IRHITAALLQDLSYLMVLIYPGTRLFKRLSNIITLCRIIV"
FT   gene            27929..28936
FT                   /gene="KAR4"
FT                   /locus_tag="YCL055W"
FT   mRNA            27929..28936
FT                   /gene="KAR4"
FT                   /locus_tag="YCL055W"
FT                   /product="Kar4p"
FT   CDS_pept        27929..28936
FT                   /codon_start=1
FT                   /gene="KAR4"
FT                   /locus_tag="YCL055W"
FT                   /product="Kar4p"
FT                   /note="Transcription factor required for response to
FT                   pheromones; also required during meiosis; exists in two
FT                   forms, a slower-migrating form more abundant during
FT                   vegetative growth and a faster-migrating form induced by
FT                   pheromone"
FT                   /db_xref="GOA:P25583"
FT                   /db_xref="InterPro:IPR007757"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25583"
FT                   /experiment="EXISTENCE:direct assay:GO:0003700 DNA-binding
FT                   transcription factor activity [PMID:17101777]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
FT                   [PMID:14562095]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
FT                   [PMID:14562095]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005829 cytosol
FT                   [PMID:26928762]"
FT                   /experiment="EXISTENCE:direct assay:GO:0007329 positive
FT                   regulation of transcription from RNA polymerase II promoter
FT                   by pheromones [PMID:17101777]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0003700
FT                   DNA-binding transcription factor activity [PMID:17101777]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0007329
FT                   positive regulation of transcription from RNA polymerase II
FT                   promoter by pheromones [PMID:17101777]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000742
FT                   karyogamy involved in conjugation with cellular fusion
FT                   [PMID:8754797]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0003700
FT                   DNA-binding transcription factor activity [PMID:17101777]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0007329 positive
FT                   regulation of transcription from RNA polymerase II promoter
FT                   by pheromones [PMID:17101777]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0051321 meiotic
FT                   cell cycle [PMID:8754797]"
FT                   /protein_id="DAA07431.1"
FT                   /translation="MAFQDPTYDQNKSRHINNSHLQGPNQETIEMKSKHVSFKPSRDFH
FT                   TNDYSNNYIHGKSLPQQHVTNIENRVDGYPKLQKLFQAKAKQINQFATTPFGCKIGIDS
FT                   IVPTLNHWIQNENLTFDVVMIGCLTENQFIYPILTQLPLDRLISKPGFLFIWANSQKIN
FT                   ELTKLLNNEIWAKKFRRSEELVFVPIDKKSPFYPGLDQDDETLMEKMQWHCWMCITGTV
FT                   RRSTDGHLIHCNVDTDLSIETKDTTNGAVPSHLYRIAENFSTATRRLHIIPARTGYETP
FT                   VKVRPGWVIVSPDVMLDNFSPKRYKEEIANLGSNIPLKNEIELLRPRSPVQKAQ"
FT   rep_origin      30200..30657
FT                   /note="ARS304; Autonomously Replicating Sequence on
FT                   Chromosome III"
FT   gene            30910..30996
FT                   /gene="RDT1"
FT                   /locus_tag="YCL054W-A"
FT   mRNA            30910..30996
FT                   /gene="RDT1"
FT                   /locus_tag="YCL054W-A"
FT                   /product="Rdt1p"
FT   CDS_pept        30910..30996
FT                   /codon_start=1
FT                   /gene="RDT1"
FT                   /locus_tag="YCL054W-A"
FT                   /product="Rdt1p"
FT                   /note="Short open reading frame, shows evidence of
FT                   translation; may be new protein-coding gene that originated
FT                   de novo from noncoding sequence; same allele found in at
FT                   least 33 other S. cerevisiae strains; at least 3 strains
FT                   have a second allele with three nucleotide substitutions
FT                   leading to two amino acid differences"
FT                   /db_xref="GOA:A0A0B7P221"
FT                   /db_xref="UniProtKB/Swiss-Prot:A0A0B7P221"
FT                   /protein_id="DAA64696.1"
FT                   /translation="MIRQKIFVFIVKSRRNSICPAIRRKEDY"
FT   gene            31449..33974
FT                   /gene="SPB1"
FT                   /locus_tag="YCL054W"
FT   mRNA            31449..33974
FT                   /gene="SPB1"
FT                   /locus_tag="YCL054W"
FT                   /product="27S pre-rRNA
FT                   (guanosine2922-2'-O)-methyltransferase"
FT   CDS_pept        31449..33974
FT                   /codon_start=1
FT                   /gene="SPB1"
FT                   /locus_tag="YCL054W"
FT                   /product="27S pre-rRNA
FT                   (guanosine2922-2'-O)-methyltransferase"
FT                   /EC_number="2.1.1.167"
FT                   /note="AdoMet-dependent methyltransferase; involved in rRNA
FT                   processing and 60S ribosomal subunit maturation; methylates
FT                   G2922 in the tRNA docking site of the large subunit rRNA
FT                   and in the absence of snR52, U2921; suppressor of PAB1
FT                   mutants"
FT                   /db_xref="GOA:P25582"
FT                   /db_xref="InterPro:IPR002877"
FT                   /db_xref="InterPro:IPR012920"
FT                   /db_xref="InterPro:IPR015507"
FT                   /db_xref="InterPro:IPR024576"
FT                   /db_xref="InterPro:IPR028589"
FT                   /db_xref="InterPro:IPR029063"
FT                   /db_xref="PDB:6ELZ"
FT                   /db_xref="PDB:6EM5"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25582"
FT                   /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
FT                   [PMID:10556316]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005730 nucleolus
FT                   [PMID:10556316|PMID:10648622]"
FT                   /experiment="EXISTENCE:direct assay:GO:0030687 preribosome,
FT                   large subunit precursor [PMID:11583614]"
FT                   /experiment="EXISTENCE:direct assay:GO:0031167 rRNA
FT                   methylation [PMID:15546625]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0008650 rRNA
FT                   (uridine-2'-O-)-methyltransferase activity [PMID:14636587]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0031167 rRNA
FT                   methylation [PMID:14636587|PMID:15546625]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000463
FT                   maturation of LSU-rRNA from tricistronic rRNA transcript
FT                   (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FT                   [PMID:10556316|PMID:10648622]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000466
FT                   maturation of 5.8S rRNA from tricistronic rRNA transcript
FT                   (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FT                   [PMID:10556316|PMID:10648622]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0016435 rRNA
FT                   (guanine) methyltransferase activity [PMID:15546625]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0031167 rRNA
FT                   methylation [PMID:15546625]"
FT                   /protein_id="DAA07432.1"
FT                   /translation="MGKTQKKNSKGRLDRYYYLAKEKGYRARSSFKIIQINEKYGHFLE
FT                   KSKVVIDLCAAPGSWCQVASKLCPVNSLIIGVDIVPMKPMPNVITFQSDITTEDCRSKL
FT                   RGYMKTWKADTVLHDGAPNVGLGWVQDAFTQSQLTLQALKLAVENLVVNGTFVTKIFRS
FT                   KDYNKLIWVFQQLFEKVEATKPPASRNVSAEIFVVCKGFKAPKRLDPRLLDPKEVFEEL
FT                   PDGQQNMESKIYNPEKKVRKRQGYEEGDNLLYHETSILDFVRTEDPISMLGEMNKFTID
FT                   ENDHEWKILKKLKQTTDEFRSCIEDLKVLGKKDFKMILRWRKIAREILGIEVKDDAKTE
FT                   IEVVPLTEEEQIEKDLQGLQEKQRLNVKRERRRKNEMKQKELQRMQMNMITPTDIGIEA
FT                   ASLGKESLFNLKTAEKTGILNDLAKGKKRMIFTDDELAKDNDIYIDENIMIKDKDSAAD
FT                   ADDLESELNAMYSDYKTRRSERDAKFRAKQARGGDNEEEWTGFNEGSLEKKEEEGKDYI
FT                   EDNDDEGVEGDSDDDEAITNLISKLKGQEGDHKLSSKARMIFNDPIFNNVEPDLPVNTV
FT                   NDGIMSSESVGDISKLNKKRKHEEMHQKQDEADSSDESSSDDSDFEIVANDNASEEFDS
FT                   DYDSEEEKNQTKKEKHSRDIDIATVEAMTLAHQLALGQKNKHDLVDEGFNRYTFRDTEN
FT                   LPDWFLEDEKEHSKINKPITKEAAMAIKEKIKAMNARPIKKVAEAKARKRMRAVARLEK
FT                   IKKKAGLINDDSDKTEKDKAEEISRLMRKVTKKPKTKPKVTLVVASGRNKGLAGRPKGV
FT                   KGKYKMVDGVMKNEQRALRRIAKKHHKKK"
FT   gene            complement(34143..35393)
FT                   /gene="PBN1"
FT                   /locus_tag="YCL052C"
FT   mRNA            complement(34143..35393)
FT                   /gene="PBN1"
FT                   /locus_tag="YCL052C"
FT                   /product="Pbn1p"
FT   CDS_pept        complement(34143..35393)
FT                   /codon_start=1
FT                   /gene="PBN1"
FT                   /locus_tag="YCL052C"
FT                   /product="Pbn1p"
FT                   /note="Component of
FT                   glycosylphosphatidylinositol-mannosyltransferase I;
FT                   essential component; required for the autocatalytic
FT                   post-translational processing of the protease B precursor
FT                   Prb1p; localizes to ER in lumenal orientation; homolog of
FT                   mammalian PIG-X"
FT                   /db_xref="GOA:P25580"
FT                   /db_xref="InterPro:IPR013233"
FT                   /db_xref="InterPro:IPR042322"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25580"
FT                   /experiment="EXISTENCE:direct assay:GO:0000030
FT                   mannosyltransferase activity [PMID:15635094]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
FT                   reticulum [PMID:9649520|PMID:26928762]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006506 GPI
FT                   anchor biosynthetic process [PMID:15635094]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0016485 protein
FT                   processing [PMID:9649520]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0030433
FT                   ubiquitin-dependent ERAD pathway [PMID:16418276]"
FT                   /experiment="EXISTENCE:physical interaction:GO:1990529
FT                   glycosylphosphatidylinositol-mannosyltransferase I complex
FT                   [PMID:15635094]"
FT                   /protein_id="DAA07433.1"
FT                   /translation="MVTRHRVTVLYNAPEDIGNHMRQNDTHLTVRGGSGVVLQQRWLLE
FT                   RTGSLDKSFTRITWRPRADLARSLSVIENELSAGFSVYSNSSDVPERFITNPVYNSFHS
FT                   EKFDIEQYLPPEVDLNLSWNPEDFTYDISVEPTQIQIVEYRLLKQGEEFTIARVKDEKL
FT                   EVGVFFVDASDESDVDIGGIRCNWRMDDGKMERCQKTSLLYKQGHIAYNHSTTTTSLYL
FT                   NEPIGLHPKIMIDLTDFEERPKCMYLMHLQLPLELFIDKFQSSPLLLFGEDDLELPEYS
FT                   LRDKAWGSESIFELKAGTMNEVTLHTRYIEPSNNKGDKLEVSFDPEVILACDTGDNKVS
FT                   RNPFYKKGLGYESLFTDDTTFRHLNSTTLLVPIPRPDTKDYSKIKNGTLLCLLISIIYI
FT                   FSKVFGNNKKKRSVKRE"
FT   gene            35865..37616
FT                   /gene="LRE1"
FT                   /locus_tag="YCL051W"
FT   mRNA            35865..37616
FT                   /gene="LRE1"
FT                   /locus_tag="YCL051W"
FT                   /product="Lre1p"
FT   CDS_pept        35865..37616
FT                   /codon_start=1
FT                   /gene="LRE1"
FT                   /locus_tag="YCL051W"
FT                   /product="Lre1p"
FT                   /note="Protein involved in control of cell wall structure
FT                   and stress response; direct inhibitor of the nuclear Dbf2
FT                   related (NDR) kinase Cbk1p-Mob2p; overproduction confers
FT                   resistance to cell-wall degrading enzymes; exhibits genetic
FT                   interactions with genes involved in the cell wall integrity
FT                   pathway; LRE1 has a paralog, HLR1, that arose from the
FT                   whole genome duplication"
FT                   /db_xref="GOA:P25579"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25579"
FT                   /experiment="EXISTENCE:direct assay:GO:0004860 protein
FT                   kinase inhibitor activity [PMID:23954433]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005935 cellular bud
FT                   neck [PMID:23954433]"
FT                   /experiment="EXISTENCE:direct assay:GO:0006469 negative
FT                   regulation of protein kinase activity [PMID:23954433]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0031505
FT                   fungal-type cell wall organization [PMID:11532139]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0031505
FT                   fungal-type cell wall organization [PMID:9090049]"
FT                   /protein_id="DAA07434.1"
FT                   /translation="MPNTHTQHVQISEPNPVNTLSTPSKRGHRHRRSLAISGDFDFLKQ
FT                   PAAIVNLPPPQAAENCPSTAPTAVSSTLSPIRYNRFPCKTNEDAGTLDLPEPRFYPLSP
FT                   KNNLQTPSPRFFISEEPSFSSPVKGVPDAIINLDDALKTRPRSFKSHRRSESAPPDLEV
FT                   MVDKGNCAAGSNSMIKEEEDSLIEPESKNEYYEQKLPTALLSPLRPSLCVSEQAIDVDD
FT                   SALNGSPTHHNHGMQNANARNSNTFNSLKIKGQKQRYYHYTKQLPLTVGCDSQSPKEQR
FT                   SAASMTINQAMTPSSLAYTPSKLASTPATPVSFYDSNADINLESDNFPLKDNPRYAKDG
FT                   YPKKCGNSQLNRVLDSDKRQDFSGESRRRRSGSPISHMQHRNLIDNMKGRRNSNTINSI
FT                   FNYKSQHYEMPYDDMMKNENINAQSMPFSVNGVNNENSIGGVITRADDAPLQHSVVKSC
FT                   TPDGKEEMNRLKSNDSNEYSKSEGQIRTNSQLSKDILMGEPGDMVDLSSFVNAQRKASN
FT                   ETGDLVFSLSQDDDALKTFHASNSAATSNESWCISDDALGKQAQDSEVRRKRKSKLGLF
FT                   RHIFSRK"
FT   gene            complement(37836..38801)
FT                   /gene="APA1"
FT                   /gene_synonym="DTP1"
FT                   /locus_tag="YCL050C"
FT   mRNA            complement(37836..38801)
FT                   /gene="APA1"
FT                   /gene_synonym="DTP1"
FT                   /locus_tag="YCL050C"
FT                   /product="bifunctional AP-4-A phosphorylase/ADP
FT                   sulfurylase"
FT   CDS_pept        complement(37836..38801)
FT                   /codon_start=1
FT                   /gene="APA1"
FT                   /gene_synonym="DTP1"
FT                   /locus_tag="YCL050C"
FT                   /product="bifunctional AP-4-A phosphorylase/ADP
FT                   sulfurylase"
FT                   /EC_number="2.7.7.5"
FT                   /EC_number="2.7.7.53"
FT                   /note="AP4A phosphorylase; bifunctional diadenosine
FT                   5',5'''-P1,P4-tetraphosphate phosphorylase and ADP
FT                   sulfurylase involved in catabolism of bis(5'-nucleosidyl)
FT                   tetraphosphates; catalyzes phosphorolysis of dinucleoside
FT                   oligophosphates, cleaving substrates' alpha/beta-anhydride
FT                   bond and introducing Pi into the beta-position of the
FT                   corresponding NDP formed; protein abundance increases under
FT                   DNA replication stress; APA1 has a paralog, APA2, that
FT                   arose from the whole genome duplication"
FT                   /db_xref="GOA:P16550"
FT                   /db_xref="InterPro:IPR009163"
FT                   /db_xref="InterPro:IPR019200"
FT                   /db_xref="InterPro:IPR036265"
FT                   /db_xref="UniProtKB/Swiss-Prot:P16550"
FT                   /experiment="EXISTENCE:direct assay:GO:0004780 sulfate
FT                   adenylyltransferase (ADP) activity [PMID:2556364]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
FT                   [PMID:14562095]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
FT                   [PMID:14562095]"
FT                   /experiment="EXISTENCE:direct assay:GO:0008796
FT                   bis(5'-nucleosyl)-tetraphosphatase activity
FT                   [PMID:2174863|PMID:2556364]"
FT                   /experiment="EXISTENCE:direct assay:GO:0009164 nucleoside
FT                   catabolic process [PMID:2174863]"
FT                   /experiment="EXISTENCE:direct assay:GO:0009165 nucleotide
FT                   biosynthetic process [PMID:2172926]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0008796
FT                   bis(5'-nucleosyl)-tetraphosphatase activity [PMID:2174863]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0009164
FT                   nucleoside catabolic process [PMID:2174863]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0004780 sulfate
FT                   adenylyltransferase (ADP) activity [PMID:2556364]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0008796
FT                   bis(5'-nucleosyl)-tetraphosphatase activity
FT                   [PMID:2174863|PMID:2556364]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0009164
FT                   nucleoside catabolic process [PMID:2174863]"
FT                   /protein_id="DAA07435.1"
FT                   /translation="MSIPADIASLISDKYKSAFDNGNLKFIQTETTKTKDPKTSMPYLI
FT                   SHMPSLIEKPERGQTPEGEDPLGKPEEELTVIPEFGGADNKAYKLLLNKFPVIPEHTLL
FT                   VTNEYQHQTDALTPTDLLTAYKLLCALDNEESDKRHMVFYNSGPASGSSLDHKHLQILQ
FT                   MPEKFVTFQDRLCNGKEHFLPTFNTEPLQDAKVSFAHFVLPMPESEETVDEDLLAMCYI
FT                   SILQRALTFFQDWLNENPELKKSYNLMLTKEWICVVPRSKAFSDEMKIGFNSTGYCGMI
FT                   LTKNDEVFSKITEKPELINDILLECGFPNTSGQKPNEYNY"
FT   rep_origin      39508..39595
FT                   /note="ARS305; Efficient early-firing replication origin on
FT                   Chromosome III"
FT   gene            complement(39786..40724)
FT                   /locus_tag="YCL049C"
FT   mRNA            complement(39786..40724)
FT                   /locus_tag="YCL049C"
FT                   /product="hypothetical protein"
FT   CDS_pept        complement(39786..40724)
FT                   /codon_start=1
FT                   /locus_tag="YCL049C"
FT                   /product="hypothetical protein"
FT                   /note="hypothetical protein; localizes to membrane
FT                   fraction; YCL049C is not an essential gene"
FT                   /db_xref="GOA:P25577"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25577"
FT                   /experiment="EXISTENCE:direct assay:GO:0016020 membrane
FT                   [PMID:11935221]"
FT                   /protein_id="DAA07436.1"
FT                   /translation="MFSKYLVTASSLFVALTSAASTVDLDALLLLPGVESHDGVDTVFS
FT                   TKDFYQVSFVKSIAPAIVNSSVIFHDVSRGVAMGNVKSRASIFNPEETYYDWEQYQVVN
FT                   NGDWRTEWAPASDCIWREEKDNSDETPDRFPISVPYNWTSQYSIVDYDTDANEDNLDFR
FT                   FIKSLLDKKNWLKKINQTVSQSSIMVAPMIRPYNVVQLWYSKDMVWANVQRQYCSGVYP
FT                   GGTQCSAWSRYYHVDAPTCDEPVASYMTKMLENEVQCPNERNATTLEPLRLNKQGDSDF
FT                   SLTFEEEEEEETGSKSLWSTLKKIFSKRSIS"
FT   gene            41488..41727
FT                   /locus_tag="YCL048W-A"
FT   mRNA            41488..41727
FT                   /locus_tag="YCL048W-A"
FT                   /product="hypothetical protein"
FT   CDS_pept        41488..41727
FT                   /codon_start=1
FT                   /locus_tag="YCL048W-A"
FT                   /product="hypothetical protein"
FT                   /note="hypothetical protein; SWAT-GFP and mCherry fusion
FT                   proteins localize to the cell periphery and vacuole;
FT                   YCL048W-A has a paralog, YDR524C-B, that arose from the
FT                   whole genome duplication"
FT                   /db_xref="EnsemblGenomes-Gn:YCL048W-A"
FT                   /db_xref="EnsemblGenomes-Tr:YCL048W-A"
FT                   /db_xref="GOA:Q2V2Q2"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q2V2Q2"
FT                   /experiment="EXISTENCE:direct assay:GO:0000324 fungal-type
FT                   vacuole [PMID:26928762]"
FT                   /experiment="EXISTENCE:direct assay:GO:0071944 cell
FT                   periphery [PMID:26928762]"
FT                   /protein_id="DAA07437.1"
FT                   /translation="MQIKNIVAVLATVTAINAQVGIEPNATTPNATQPNATQPNTTLPT
FT                   ASVTTTVSIGEAVVNTMAAGAFGAAIAAGVAFLF"
FT   gene            42165..43556
FT                   /gene="SPS22"
FT                   /locus_tag="YCL048W"
FT   mRNA            42165..43556
FT                   /gene="SPS22"
FT                   /locus_tag="YCL048W"
FT                   /product="Sps22p"
FT   CDS_pept        42165..43556
FT                   /codon_start=1
FT                   /gene="SPS22"
FT                   /locus_tag="YCL048W"
FT                   /product="Sps22p"
FT                   /note="hypothetical protein; SPS22 has a paralog, SPS2,
FT                   that arose from the whole genome duplication; redundant
FT                   with Sps2p for the organization of the beta-glucan layer of
FT                   the spore wall"
FT                   /db_xref="GOA:P25380"
FT                   /db_xref="InterPro:IPR036941"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25380"
FT                   /experiment="EXISTENCE:direct assay:GO:0005829 cytosol
FT                   [PMID:26928762]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0030476
FT                   ascospore wall assembly [PMID:15590821]"
FT                   /protein_id="DAA07438.1"
FT                   /translation="MNRITRKSCLFAIIFASLFVTHALGAAIDPPRRPHNVKPFHNGNL
FT                   ELQRRANEPFFEIDVKSLNTNSPISELCKKDLHVIESSHDLFHLQNQCEFILGSLKVTN
FT                   YDSNILDLNSLRAIGGDLIIQDSPELIRIQAGNLNKIEGLFQLQGLTSLVSVEIPTLKF
FT                   CQSLEWKVVPILNYVSMDSQNIEIIKDIVISDTSLANIENFNKVQEIDTFNINNNRFLE
FT                   TIHSNVKTIRGQFSVHANAKELELEMPHLREVENITIRDTSLVYLPQLTKVKSSLEFIE
FT                   NYFYELNLNNLQKIGGTLGIINNVNLIKVNLENLTDIQGGLMIADNESLEDITFLPNLK
FT                   QIGGAIFFEGSFKDIMFDSLKLVKGSAFIKSSSNVLDCNKWTNPSNGRSIIRGGKFTCI
FT                   SGKKENTLNVKQDGTIIEKGYKDLTQEGEDSKKRVISKYANSANPSMQLDPLLFGTCLV
FT                   AMLLF"
FT   gene            complement(43661..44437)
FT                   /gene="POF1"
FT                   /locus_tag="YCL047C"
FT   mRNA            complement(43661..44437)
FT                   /gene="POF1"
FT                   /locus_tag="YCL047C"
FT                   /product="nicotinamide-nucleotide adenylyltransferase"
FT   CDS_pept        complement(43661..44437)
FT                   /codon_start=1
FT                   /gene="POF1"
FT                   /locus_tag="YCL047C"
FT                   /product="nicotinamide-nucleotide adenylyltransferase"
FT                   /EC_number="2.7.7.1"
FT                   /note="Nicotinamide mononucleotide-specific
FT                   adenylyltransferase (NMNAT); catalyzes the conversion of
FT                   nicotinamide mononucleotide (NMN) to nicotinamide adenine
FT                   dinucleotide (NAD+); role in the nicotinamide riboside (NR)
FT                   salvage pathway of NAD+ biosynthesis; involved in NR and
FT                   NAD+ homeostasis; ATPase involved in protein quality
FT                   control and filamentation pathways; interacts physically
FT                   with Kss1p and suppresses the filamentation defect of a
FT                   kss1 deletion"
FT                   /db_xref="GOA:P25576"
FT                   /db_xref="InterPro:IPR004821"
FT                   /db_xref="InterPro:IPR005248"
FT                   /db_xref="InterPro:IPR014729"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25576"
FT                   /experiment="EXISTENCE:direct assay:GO:0000309
FT                   nicotinamide-nucleotide adenylyltransferase activity
FT                   [PMID:24759102]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
FT                   [PMID:24759102]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
FT                   [PMID:24759102]"
FT                   /experiment="EXISTENCE:direct assay:GO:0016887 ATPase
FT                   activity [PMID:22204397]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0000309
FT                   nicotinamide-nucleotide adenylyltransferase activity
FT                   [PMID:24759102]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0001403
FT                   invasive growth in response to glucose limitation
FT                   [PMID:21460040]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0007124
FT                   pseudohyphal growth [PMID:21460040]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0034356 NAD
FT                   biosynthesis via nicotinamide riboside salvage pathway
FT                   [PMID:24759102]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0030433
FT                   ubiquitin-dependent ERAD pathway [PMID:22204397]"
FT                   /experiment="EXISTENCE:physical interaction:GO:0030433
FT                   ubiquitin-dependent ERAD pathway [PMID:22204397]"
FT                   /protein_id="DAA07439.1"
FT                   /translation="MKKTFEQFRKSNLLFQVLKGPQHLECQKLFVLDSSFNPPHLAHFQ
FT                   LLSQTIKNFKLKDTRSHVLLLLAVNNADKLPKPASFPTRLEMMCLFADYLQEKLPQSVV
FT                   SVGLTVFSKFIDKDKILHEQFVKGCSADIGYLVGFDTIARIFDEKYYHPLKISDVMESF
FT                   MSGSQLYCLARGDCHLSAESQLRYASDILEGKFEPVIPREWGARIHVMQNDYPALRNVS
FT                   SSEIRNKLKNGQVESLKDELPLCIYDYLINNKTIFD"
FT   gene            complement(44623..46905)
FT                   /gene="EMC1"
FT                   /locus_tag="YCL045C"
FT   mRNA            complement(44623..46905)
FT                   /gene="EMC1"
FT                   /locus_tag="YCL045C"
FT                   /product="Emc1p"
FT   CDS_pept        complement(44623..46905)
FT                   /codon_start=1
FT                   /gene="EMC1"
FT                   /locus_tag="YCL045C"
FT                   /product="Emc1p"
FT                   /note="Member of conserved endoplasmic reticulum membrane
FT                   complex; involved in efficient folding of proteins in the
FT                   ER; null mutant displays induction of the unfolded protein
FT                   response; interacts with Gal80p; homologous to worm
FT                   H17B01.4/EMC-1, fly CG2943, and human KIAA0090"
FT                   /db_xref="GOA:P25574"
FT                   /db_xref="InterPro:IPR011678"
FT                   /db_xref="InterPro:IPR026895"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25574"
FT                   /experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
FT                   reticulum [PMID:14562095|PMID:26928762]"
FT                   /experiment="EXISTENCE:direct assay:GO:0072546 ER membrane
FT                   protein complex [PMID:19325107]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0034975
FT                   protein folding in endoplasmic reticulum [PMID:19325107]"
FT                   /protein_id="DAA07440.1"
FT                   /translation="MKITCTDLVYVFILLFLNTSCVQAVFSDDAFITDWQLANLGPWEK
FT                   VIPDSRDRNRVLILSNPTETSCLVSSFNVSSGQILFRNVLPFTIDEIQLDSNDHNAMVC
FT                   VNSSSNHWQKYDLHDWFLLEEGVDNAPSTTILPQSSYLNDQVSIKNNELHILDEQSKLA
FT                   EWKLELPQGFNKVEYFHREDPLALVLNVNDTQYMGFSANGTELIPVWQRDEWLTNVVDY
FT                   AVLDVFDSRDVELNKDMKAELDSNSLWNAYWLRLTTNWNRLINLLKENQFSPGRVFTKL
FT                   LALDAKDTTVSDLKFGFAKILIVLTHDGFIGGLDMVNKGQLIWKLDLEIDQGVKMFWTD
FT                   KNHDELVVFSHDGHYLTIEVTKDQPIIKSRSPLSERKTVDSVIRLNEHDHQYLIKFEDK
FT                   DHLLFKLNPGKNTDVPIVANNHSSSHIFVTEHDTNGIYGYIIENDTVKQTWKKAVNSKE
FT                   KMVAYSKRETTNLNTLGITLGDKSVLYKYLYPNLAAYLIANEEHHTITFNLIDTITGEI
FT                   LITQEHKDSPDFRFPMDIVFGEYWVVYSYFSSEPVPEQKLVVVELYESLTPDERLSNSS
FT                   DNFSYDPLTGHINKPQFQTKQFIFPEIIKTMSISKTTDDITTKAIVMELENGQITYIPK
FT                   LLLNARGKPAEEMAKDKKKEFMATPYTPVIPINDNFIITHFRNLLPGSDSQLISIPTNL
FT                   ESTSIICDLGLDVFCTRITPSGQFDLMSPTFEKGKLLITIFVLLVITYFIRPSVSNKKL
FT                   KSQWLIK"
FT   gene            complement(47111..48364)
FT                   /gene="MGR1"
FT                   /locus_tag="YCL044C"
FT   mRNA            complement(47111..48364)
FT                   /gene="MGR1"
FT                   /locus_tag="YCL044C"
FT                   /product="Mgr1p"
FT   CDS_pept        complement(47111..48364)
FT                   /codon_start=1
FT                   /gene="MGR1"
FT                   /locus_tag="YCL044C"
FT                   /product="Mgr1p"
FT                   /note="Subunit of the mitochondrial (mt) i-AAA protease
FT                   supercomplex; i-AAA degrades misfolded mitochondrial
FT                   proteins; forms a subcomplex with Mgr3p that binds to
FT                   substrates to facilitate proteolysis; required for growth
FT                   of cells lacking mtDNA"
FT                   /db_xref="GOA:P25573"
FT                   /db_xref="InterPro:IPR013911"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25573"
FT                   /experiment="EXISTENCE:direct assay:GO:0005739
FT                   mitochondrion
FT                   [PMID:14562095|PMID:14576278|PMID:16823961|PMID:24769239]"
FT                   /experiment="EXISTENCE:direct assay:GO:0031942 i-AAA
FT                   complex [PMID:16267274|PMID:18843051]"
FT                   /experiment="EXISTENCE:direct assay:GO:0051787 misfolded
FT                   protein binding [PMID:18843051]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006515 protein
FT                   quality control for misfolded or incompletely synthesized
FT                   proteins [PMID:18843051]"
FT                   /protein_id="DAA07441.1"
FT                   /translation="MAVFTPPSGNSNSTDHTHTQDDHDKDDNDIKKFYIRPSLGLKLWG
FT                   PLVPAPDNLPGLYTLITIQSAVGFFALWRLRRLYKLPPPRRIATGTHSDLSFGELPSEM
FT                   IVNGKTKIKKDIADFPTLNRFSTTHGDIVLAPPPIIPRQSRFVSVRKLLWGLFGSLLLS
FT                   QSLLELTRLNFLKYDPWCDEMKSVRDKKFFNNIVKYYHEGIDPTKIKVKDAMNGTPLST
FT                   NIPEVKQSVALARAQVEAQNPIIKWFGPLEYKPMSFNEYLNRMEFHLDMFEFFQNKRNI
FT                   RENSIELINSISHNPQSSSTGLEGLSESKKLHLQNVEKRLHFLASSGDSISAPVKKRSS
FT                   TTLSRGVILPHDTKGPQDIDLDTIRSLYDPWMTLALETSLSIKFIPTTMPSHTKTPTST
FT                   DQPLPGPTPKALTNEKTH"
FT   gene            complement(48653..50221)
FT                   /gene="PDI1"
FT                   /gene_synonym="MFP1"
FT                   /gene_synonym="TRG1"
FT                   /locus_tag="YCL043C"
FT   mRNA            complement(48653..50221)
FT                   /gene="PDI1"
FT                   /gene_synonym="MFP1"
FT                   /gene_synonym="TRG1"
FT                   /locus_tag="YCL043C"
FT                   /product="protein disulfide isomerase PDI1"
FT   CDS_pept        complement(48653..50221)
FT                   /codon_start=1
FT                   /gene="PDI1"
FT                   /gene_synonym="MFP1"
FT                   /gene_synonym="TRG1"
FT                   /locus_tag="YCL043C"
FT                   /product="protein disulfide isomerase PDI1"
FT                   /EC_number="5.3.4.1"
FT                   /note="Protein disulfide isomerase; multifunctional
FT                   oxidoreductase of the ER lumen, essential for disulfide
FT                   bond formation in secretory and cell-surface proteins,
FT                   processing of non-native disulfide bonds; Ero1p activator;
FT                   complexes with exomannosidase, Mnl1p to facilitate the
FT                   recognition of misfolded glycoproteins and the trimming of
FT                   glycan Man8GlcNAc2 to Man7GlcNAc2 on substrates, thereby
FT                   accelerating ERAD; PDI1 has a paralog, EUG1, that arose
FT                   from the whole genome duplication"
FT                   /db_xref="GOA:P17967"
FT                   /db_xref="InterPro:IPR005792"
FT                   /db_xref="InterPro:IPR013766"
FT                   /db_xref="InterPro:IPR017937"
FT                   /db_xref="InterPro:IPR036249"
FT                   /db_xref="PDB:2B5E"
FT                   /db_xref="PDB:3BOA"
FT                   /db_xref="UniProtKB/Swiss-Prot:P17967"
FT                   /experiment="EXISTENCE:direct assay:GO:0003756 protein
FT                   disulfide isomerase activity [PMID:16002399|PMID:16413482]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
FT                   reticulum [PMID:26928762]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005788 endoplasmic
FT                   reticulum lumen [PMID:1761554]"
FT                   /experiment="EXISTENCE:direct assay:GO:0015035 protein
FT                   disulfide oxidoreductase activity [PMID:16002399]"
FT                   /experiment="EXISTENCE:direct assay:GO:0036508 protein
FT                   alpha-1,2-demannosylation [PMID:21700223]"
FT                   /experiment="EXISTENCE:direct assay:GO:0051082 unfolded
FT                   protein binding [PMID:16002399]"
FT                   /experiment="EXISTENCE:direct assay:GO:1904382 mannose
FT                   trimming involved in glycoprotein ERAD pathway
FT                   [PMID:21700223|PMID:27053108]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:1904382
FT                   mannose trimming involved in glycoprotein ERAD pathway
FT                   [PMID:21700223]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0003756 protein
FT                   disulfide isomerase activity [PMID:11157982]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006457 protein
FT                   folding [PMID:11157982]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:1904382 mannose
FT                   trimming involved in glycoprotein ERAD pathway
FT                   [PMID:21700223]"
FT                   /experiment="EXISTENCE:physical interaction:GO:0005515
FT                   protein binding [PMID:16002399]"
FT                   /protein_id="DAA07442.1"
FT                   /translation="MKFSAGAVLSWSSLLLASSVFAQQEAVAPEDSAVVKLATDSFNEY
FT                   IQSHDLVLAEFFAPWCGHCKNMAPEYVKAAETLVEKNITLAQIDCTENQDLCMEHNIPG
FT                   FPSLKIFKNSDVNNSIDYEGPRTAEAIVQFMIKQSQPAVAVVADLPAYLANETFVTPVI
FT                   VQSGKIDADFNATFYSMANKHFNDYDFVSAENADDDFKLSIYLPSAMDEPVVYNGKKAD
FT                   IADADVFEKWLQVEALPYFGEIDGSVFAQYVESGLPLGYLFYNDEEELEEYKPLFTELA
FT                   KKNRGLMNFVSIDARKFGRHAGNLNMKEQFPLFAIHDMTEDLKYGLPQLSEEAFDELSD
FT                   KIVLESKAIESLVKDFLKGDASPIVKSQEIFENQDSSVFQLVGKNHDEIVNDPKKDVLV
FT                   LYYAPWCGHCKRLAPTYQELADTYANATSDVLIAKLDHTENDVRGVVIEGYPTIVLYPG
FT                   GKKSESVVYQGSRSLDSLFDFIKENGHFDVDGKALYEEAQEKAAEEADADAELADEEDA
FT                   IHDEL"
FT   gene            50584..50943
FT                   /locus_tag="YCL042W"
FT   mRNA            50584..50943
FT                   /locus_tag="YCL042W"
FT                   /product="hypothetical protein"
FT   CDS_pept        50584..50943
FT                   /codon_start=1
FT                   /locus_tag="YCL042W"
FT                   /product="hypothetical protein"
FT                   /note="hypothetical protein; epitope-tagged protein
FT                   localizes to the cytoplasm"
FT                   /db_xref="GOA:P25572"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25572"
FT                   /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
FT                   [PMID:11914276]"
FT                   /protein_id="DAA07443.1"
FT                   /translation="MEKKKILDAALAPRIISGVPTDGQPLSGGPLSWAWCHTTLKRWAL
FT                   MKTRPYKYPLSTEPPTPPSVPNSASVNHNTTTNTTLSYTRCHSTTYTKPLRERSSRPWT
FT                   RSATISRLPPRSWTN"
FT   gene            50838..52340
FT                   /gene="GLK1"
FT                   /gene_synonym="HOR3"
FT                   /locus_tag="YCL040W"
FT   mRNA            50838..52340
FT                   /gene="GLK1"
FT                   /gene_synonym="HOR3"
FT                   /locus_tag="YCL040W"
FT                   /product="glucokinase"
FT   CDS_pept        50838..52340
FT                   /codon_start=1
FT                   /gene="GLK1"
FT                   /gene_synonym="HOR3"
FT                   /locus_tag="YCL040W"
FT                   /product="glucokinase"
FT                   /EC_number="2.7.1.2"
FT                   /note="Glucokinase; catalyzes the phosphorylation of
FT                   glucose at C6 in the first irreversible step of glucose
FT                   metabolism; one of three glucose phosphorylating enzymes;
FT                   expression regulated by non-fermentable carbon sources;
FT                   GLK1 has a paralog, EMI2, that arose from the whole genome
FT                   duplication"
FT                   /db_xref="GOA:P17709"
FT                   /db_xref="InterPro:IPR001312"
FT                   /db_xref="InterPro:IPR019807"
FT                   /db_xref="InterPro:IPR022672"
FT                   /db_xref="InterPro:IPR022673"
FT                   /db_xref="UniProtKB/Swiss-Prot:P17709"
FT                   /experiment="EXISTENCE:direct assay:GO:0004340 glucokinase
FT                   activity [PMID:8501032]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005829 cytosol
FT                   [PMID:14562095]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005886 plasma
FT                   membrane [PMID:16622836]"
FT                   /experiment="EXISTENCE:direct assay:GO:0006013 mannose
FT                   metabolic process [PMID:237183]"
FT                   /experiment="EXISTENCE:direct assay:GO:0006096 glycolytic
FT                   process [PMID:8501032]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0046323
FT                   glucose import [PMID:6300872]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0004340
FT                   glucokinase activity [PMID:6341351]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006006 glucose
FT                   metabolic process [PMID:6300872]"
FT                   /protein_id="DAA07444.1"
FT                   /translation="MSFDDLHKATERAVIQAVDQICDDFEVTPEKLDELTAYFIEQMEK
FT                   GLAPPKEGHTLASDKGLPMIPAFVTGSPNGTERGVLLAADLGGTNFRICSVNLHGDHTF
FT                   SMEQMKSKIPDDLLDDENVTSDDLFGFLARRTLAFMKKYHPDELAKGKDAKPMKLGFTF
FT                   SYPVDQTSLNSGTLIRWTKGFRIADTVGKDVVQLYQEQLSAQGMPMIKVVALTNDTVGT
FT                   YLSHCYTSDNTDSMTSGEISEPVIGCIFGTGTNGCYMEEINKITKLPQELRDKLIKEGK
FT                   THMIINVEWGSFDNELKHLPTTKYDVVIDQKLSTNPGFHLFEKRVSGMFLGEVLRNILV
FT                   DLHSQGLLLQQYRSKEQLPRHLTTPFQLSSEVLSHIEIDDSTGLRETELSLLQSLRLPT
FT                   TPTERVQIQKLVRAISRRSAYLAAVPLAAILIKTNALNKRYHGEVEIGCDGSVVEYYPG
FT                   FRSMLRHALALSPLGAEGERKVHLKIAKDGSGVGAALCALVA"
FT   gene            52645..54882
FT                   /gene="GID7"
FT                   /gene_synonym="MOH2"
FT                   /locus_tag="YCL039W"
FT   mRNA            52645..54882
FT                   /gene="GID7"
FT                   /gene_synonym="MOH2"
FT                   /locus_tag="YCL039W"
FT                   /product="glucose-induced degradation complex subunit GID7"
FT   CDS_pept        52645..54882
FT                   /codon_start=1
FT                   /gene="GID7"
FT                   /gene_synonym="MOH2"
FT                   /locus_tag="YCL039W"
FT                   /product="glucose-induced degradation complex subunit GID7"
FT                   /note="Subunit of GID Complex that binds directly to
FT                   central component Vid30p; GID complex is involved in
FT                   proteasome-dependent catabolite inactivation of
FT                   fructose-1,6-bisphosphatase; Gid7p contains six WD40
FT                   repeats; computational analysis suggests that Gid7p and
FT                   Moh1p have similar functions"
FT                   /db_xref="GOA:P25569"
FT                   /db_xref="InterPro:IPR001680"
FT                   /db_xref="InterPro:IPR015943"
FT                   /db_xref="InterPro:IPR017986"
FT                   /db_xref="InterPro:IPR036322"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25569"
FT                   /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
FT                   [PMID:14562095]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
FT                   [PMID:14562095]"
FT                   /experiment="EXISTENCE:direct assay:GO:0034657 GID complex
FT                   [PMID:18508925]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0043161
FT                   proteasome-mediated ubiquitin-dependent protein catabolic
FT                   process [PMID:12686616]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0045721 negative
FT                   regulation of gluconeogenesis [PMID:12686616]"
FT                   /protein_id="DAA07445.1"
FT                   /translation="MSHTNKIAYVLNNDTEETASPSSVGCFDKKQLTKLLIHTLKELGY
FT                   DSAANQLLLESGGYQNESNHIQTFFKLIKTGQFHLINWQIVCSLPLAHSSPLRSEWLQR
FT                   LLIPTPTPATTSLFDHMLLQLQYLQQLMSSVNSSTCSDAEIATLRNYVEIMILVNRQIF
FT                   LEFFHPVTNSASHKGPHTALPVLYLRKILKNFIEIWDSLLVSNDQFLNEENIFNPETTL
FT                   RELSTYLTNPKLTAQLNLERDHLIDAISKYIDPNELVPKGRLLHLLKQAIKYQQSQDIF
FT                   NIIDPDDDASFSSPPHRINLLQDNFSHDLTVTFQEWKTIQDTTDEIWFLTFSPNGKYLA
FT                   SATSESSRGYFITVYDVEQDFKIYKTCVSLSQSVLYLMFSPDSRYLVACPFSEDVTIYD
FT                   MNATSLPDASATDSFLLYPSTRLSPMDSFKLDTTTYPDDTESSASSSSRPANANSNQSR
FT                   VWCCDAFHTAERAGWMVVGSPDREAIVHSLTTKESLFSLKGRTCIALGHDENISGRKSI
FT                   DPAKVLYKPTSSNGNWQYVEDDETFPRVHDVKISYDDKYVLLMTHQGVIDVYDFSGFPS
FT                   KEELSKQTVDPKNFLIPRIARLDVGKNMTCISLPLNTTHQGFHRQQISESQHLVLVSLQ
FT                   DNELQMWDYKENILIQKYFGQKQQHFIIRSCFAYGNKLVMSGSEDGKIYIWDRIRGNLV
FT                   SVLSGHSTVMSNSTKPMGKNCNVVASNPADKEMFASGGDDGKIKIWKISRN"
FT   gene            complement(54941..56527)
FT                   /gene="ATG22"
FT                   /gene_synonym="AUT4"
FT                   /locus_tag="YCL038C"
FT   mRNA            complement(54941..56527)
FT                   /gene="ATG22"
FT                   /gene_synonym="AUT4"
FT                   /locus_tag="YCL038C"
FT                   /product="Atg22p"
FT   CDS_pept        complement(54941..56527)
FT                   /codon_start=1
FT                   /gene="ATG22"
FT                   /gene_synonym="AUT4"
FT                   /locus_tag="YCL038C"
FT                   /product="Atg22p"
FT                   /note="Vacuolar integral membrane protein required for
FT                   efflux of amino acids; required for efflux of amino acids
FT                   during autophagic body breakdown in the vacuole; null
FT                   mutation causes a gradual loss of viability during
FT                   starvation"
FT                   /db_xref="GOA:P25568"
FT                   /db_xref="InterPro:IPR024671"
FT                   /db_xref="InterPro:IPR036259"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25568"
FT                   /experiment="EXISTENCE:direct assay:GO:0071627 integral
FT                   component of fungal-type vacuolar membrane [PMID:17021250]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0032974 amino
FT                   acid transmembrane export from vacuole [PMID:17021250]"
FT                   /protein_id="DAA07446.1"
FT                   /translation="MSYGTINDMNESVTNYRIKKAQNNIKGWYAYSFSSEPFVVSAVST
FT                   YIPLLLQQFASINGVKVHDHSIPCLSETGSDSDKCVLGLFNNRIFVDTSSFALYVFSLS
FT                   VLFQTIIVISVSGIVDLWGSVKFKGRILVWFGIVGALSTVAISKLNDTQIYSLAGLYIV
FT                   ANGCFGVINVVGNSLLPIFVKDSLKCQSQGAYEPDKVDSLTTVISGRGASLGYSSALIV
FT                   QIVSMFLVASKKGSKQDVQVAVLFVGIWWFVWQLPMIWLIDDVTIPIRVDDSTLASARS
FT                   PYPGEQDALGQLNWKNYLSYGWVSLFESFKHARLLKDVMIFLIAWFIISDSITTINSTA
FT                   VLFSKAELHMSTLNLIMISVLTVVNAMLGAFMIPQFLATKFRWTSSQTLMYIIIWASFI
FT                   PFYGILGFFFNAFGLKHKFEMFLLAIWYGLSLGGLSAVSRSVFSLIVPPGKESTFFSMF
FT                   SITDKGSSILGPFLVGLLTDKTHNIRYSFYFFFLLLMLSLPVLNCLDVKRGRREAEELS
FT                   QVLPESERRLD"
FT   gene            complement(57374..58678)
FT                   /gene="SRO9"
FT                   /locus_tag="YCL037C"
FT   mRNA            complement(57374..58678)
FT                   /gene="SRO9"
FT                   /locus_tag="YCL037C"
FT                   /product="Sro9p"
FT   CDS_pept        complement(57374..58678)
FT                   /codon_start=1
FT                   /gene="SRO9"
FT                   /locus_tag="YCL037C"
FT                   /product="Sro9p"
FT                   /note="Cytoplasmic RNA-binding protein; shuttles between
FT                   nucleus and cytoplasm and is exported from the nucleus in
FT                   an mRNA export-dependent manner; associates with
FT                   translating ribosomes; involved in heme regulation of Hap1p
FT                   as a component of the HMC complex, also involved in the
FT                   organization of actin filaments; contains a La motif; SRO9
FT                   has a paralog, SLF1, that arose from the whole genome
FT                   duplication"
FT                   /db_xref="GOA:P25567"
FT                   /db_xref="InterPro:IPR006630"
FT                   /db_xref="InterPro:IPR036388"
FT                   /db_xref="InterPro:IPR036390"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25567"
FT                   /experiment="EXISTENCE:direct assay:GO:0003723 RNA binding
FT                   [PMID:10564276]"
FT                   /experiment="EXISTENCE:direct assay:GO:0003729 mRNA binding
FT                   [PMID:23222640]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005844 polysome
FT                   [PMID:10564276]"
FT                   /experiment="EXISTENCE:direct assay:GO:0010494 cytoplasmic
FT                   stress granule [PMID:23222640|PMID:26777405]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006417
FT                   regulation of translation [PMID:10564276]"
FT                   /protein_id="DAA07447.1"
FT                   /translation="MSAETAAANTATAPVPEVQEQESSKSKQVNLTPAPLPTSSPWKLA
FT                   PTEIPVSTISIEDLDATRKKKNRTPTPKSSTATKWVPIKASITVSGTKRSGSKNGASNG
FT                   NSNKSKNNKTAASSTSSSNANRKKKHHQHNAKKQQQMKKDGFESAVGEEDSKDATSQEN
FT                   GQSTQQQQPPHHRNHHHSHHHNSNGPQRRKFHNSNNAGMPQNQGFPPQFKPYQGRNARN
FT                   NNNNRSKYHNHFHHNQQHPQQPMVKLQQQFYPVQPVLMAINNIARQIEYYFSEENLTVD
FT                   NYLRSKLSKDGFAPLSLISKFYRVVNMSFGGDTNLILAALREIVANEAATVNVAEGTLA
FT                   AKEGDNVTGEAKEPSPLDKYFVRSKSWSNWLPETFETEINIEKELVGDALDQFMISLPP
FT                   VPQQEEESSTELASQEQETKEDSAPVAAGESESSL"
FT   gene            59026..60726
FT                   /gene="GFD2"
FT                   /gene_synonym="YCD6"
FT                   /locus_tag="YCL036W"
FT   mRNA            59026..60726
FT                   /gene="GFD2"
FT                   /gene_synonym="YCD6"
FT                   /locus_tag="YCL036W"
FT                   /product="Gfd2p"
FT   CDS_pept        59026..60726
FT                   /codon_start=1
FT                   /gene="GFD2"
FT                   /gene_synonym="YCD6"
FT                   /locus_tag="YCL036W"
FT                   /product="Gfd2p"
FT                   /note="hypothetical protein; identified as a high-copy
FT                   suppressor of a dbp5 mutation; GFD2 has a paralog, YDR514C,
FT                   that arose from the whole genome duplication"
FT                   /db_xref="GOA:P25370"
FT                   /db_xref="InterPro:IPR012337"
FT                   /db_xref="InterPro:IPR036397"
FT                   /db_xref="InterPro:IPR040151"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25370"
FT                   /protein_id="DAA07448.1"
FT                   /translation="MQVQKMVRDNSNNGSDKSVHWERRNNNGAGPRYRSRSGNTGALAT
FT                   KLSNGTLSVRGLVKDRTGSGKIAGCVEAFLDARTQLNTPWDRAKCNWLDQIDYYVQLRK
FT                   TAFSKELDQLRKPMIDAYVAEMRQKFDASYGQSRAQLEAKLAQVDSEWHMVHGDVHAKL
FT                   EKLVEERRFLKRLSDTIVPPRSKRSQRLSPLTKEDRANCICPQPKGMSDTAWFEAIQKK
FT                   MLGMNGTIKLLETEQKLLADEKNSVRKTFWPMVEAHSRSNEFAYLEKCIRLMASQRAIC
FT                   FCLDIEAFETNQNVITEIGISIYDPRENMVPSMVPITKNYHLIIEESLELRNQKWVCDY
FT                   KDCYLLGESYVLSLKECVHFIQSLINYYLVPVTEEDKTWSRAFVGHHVSGDLKWLETIG
FT                   VKFPGRGYEGHLDHTLLLAETPGDLDVFILDTEQFYRKSYGEKGSSLGKILRLFEIPHA
FT                   FLHNAGNDAYYTLHLFMKFCDVNFRKISGMDDVLKVMGQVKVWGERDVREPKVVPMSYA
FT                   ISIEEAVKNRTYRKGVKSSRKERVCQTEFGGLTYFGTAKDAFTSTLPTH"
FT   gene            complement(60841..61173)
FT                   /gene="GRX1"
FT                   /locus_tag="YCL035C"
FT   mRNA            complement(60841..61173)
FT                   /gene="GRX1"
FT                   /locus_tag="YCL035C"
FT                   /product="dithiol glutaredoxin GRX1"
FT   CDS_pept        complement(60841..61173)
FT                   /codon_start=1
FT                   /gene="GRX1"
FT                   /locus_tag="YCL035C"
FT                   /product="dithiol glutaredoxin GRX1"
FT                   /note="Glutathione-dependent disulfide oxidoreductase;
FT                   hydroperoxide and superoxide-radical responsive,
FT                   heat-stable, with active site cysteine pair; protects cells
FT                   from oxidative damage; GRX1 has a paralog, GRX2, that arose
FT                   from the whole genome duplication; protein abundance
FT                   increases in response to DNA replication stress"
FT                   /db_xref="GOA:P25373"
FT                   /db_xref="InterPro:IPR002109"
FT                   /db_xref="InterPro:IPR011767"
FT                   /db_xref="InterPro:IPR011899"
FT                   /db_xref="InterPro:IPR014025"
FT                   /db_xref="InterPro:IPR036249"
FT                   /db_xref="PDB:2JAC"
FT                   /db_xref="PDB:2JAD"
FT                   /db_xref="PDB:3C1R"
FT                   /db_xref="PDB:3C1S"
FT                   /db_xref="PDB:6MWS"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25373"
FT                   /experiment="EXISTENCE:direct assay:GO:0004364 glutathione
FT                   transferase activity [PMID:12684511]"
FT                   /experiment="EXISTENCE:direct assay:GO:0004602 glutathione
FT                   peroxidase activity
FT                   [PMID:11875065|PMID:12684511|PMID:18992757]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
FT                   [PMID:14562095]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
FT                   [PMID:11914276|PMID:14562095]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0010731
FT                   protein glutathionylation [PMID:20074363]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0034599 cellular
FT                   response to oxidative stress [PMID:9571241]"
FT                   /protein_id="DAA07449.1"
FT                   /translation="MVSQETIKHVKDLIAENEIFVASKTYCPYCHAALNTLFEKLKVPR
FT                   SKVLVLQLNDMKEGADIQAALYEINGQRTVPNIYINGKHIGGNDDLQELRETGELEELL
FT                   EPILAN"
FT   gene            61658..62722
FT                   /gene="LSB5"
FT                   /locus_tag="YCL034W"
FT   mRNA            61658..62722
FT                   /gene="LSB5"
FT                   /locus_tag="YCL034W"
FT                   /product="Lsb5p"
FT   CDS_pept        61658..62722
FT                   /codon_start=1
FT                   /gene="LSB5"
FT                   /locus_tag="YCL034W"
FT                   /product="Lsb5p"
FT                   /note="Protein involved in membrane-trafficking events at
FT                   plasma membrane; interacts with actin regulators Sla1p and
FT                   Las17p, ubiquitin, Arf3p to couple actin dynamics to
FT                   membrane trafficking processes; similar structure to GGA
FT                   family of proteins with N-terminal VHS domain and GAT
FT                   domain; binds Las17p, which is homolog of human
FT                   Wiskott-Aldrich Syndrome protein involved in actin patch
FT                   assembly, actin polymerization; may mediate disassembly of
FT                   Pan1 complex from endocytic coat"
FT                   /db_xref="GOA:P25369"
FT                   /db_xref="InterPro:IPR008942"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25369"
FT                   /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
FT                   [PMID:18298676]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005829 cytosol
FT                   [PMID:26928762]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005938 cell cortex
FT                   [PMID:12388763|PMID:15651983|PMID:18298676]"
FT                   /experiment="EXISTENCE:direct assay:GO:0030479 actin
FT                   cortical patch [PMID:15651983]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0006897
FT                   endocytosis [PMID:12388763]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0030036 actin
FT                   cytoskeleton organization [PMID:12388763]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0051666 actin
FT                   cortical patch localization [PMID:12388763]"
FT                   /experiment="EXISTENCE:physical interaction:GO:0007015
FT                   actin filament organization [PMID:10512884]"
FT                   /protein_id="DAA07450.1"
FT                   /translation="MGFLSDHPHTAITETIFRIVSSRDYTLEVELAPLIQLIKADHNDY
FT                   NYTVNQEEAARALRKKIKYGNRLQQSRTLDLLDLFISQGVKFTVMYNDDKLLQRLRGMA
FT                   TNSENSGSGEKYEPRIIKKCAAYAISWLNYITQNNLENARAYSGLYQLGQTVKQRYSKS
FT                   SRSRRSGGGSGGRSNFMDDSADDTLYQSNSLTSADRLYRIPQINMNKEAPRIRLIISDA
FT                   LASAVSLQNSLIGLPKGKFSTDDEEATSKFIQARAIRRKVLRYLQLVTEGEFLGSLIHA
FT                   NDELVAALTAYDDRSAQDDSSDESDHGSYDDGIYDENEQDNSRYIDSESSEEESLSSYQ
FT                   PSTISNPFGDHNKI"
FT   gene            complement(62776..63282)
FT                   /gene="MXR2"
FT                   /locus_tag="YCL033C"
FT   mRNA            complement(62776..63282)
FT                   /gene="MXR2"
FT                   /locus_tag="YCL033C"
FT                   /product="peptide-methionine (R)-S-oxide reductase"
FT   CDS_pept        complement(62776..63282)
FT                   /codon_start=1
FT                   /gene="MXR2"
FT                   /locus_tag="YCL033C"
FT                   /product="peptide-methionine (R)-S-oxide reductase"
FT                   /EC_number="1.8.4.12"
FT                   /note="Methionine-R-sulfoxide reductase; involved in the
FT                   response to oxidative stress; protects iron-sulfur clusters
FT                   from oxidative inactivation along with MXR1; involved in
FT                   the regulation of lifespan"
FT                   /db_xref="GOA:P25566"
FT                   /db_xref="InterPro:IPR002579"
FT                   /db_xref="InterPro:IPR011057"
FT                   /db_xref="InterPro:IPR028427"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25566"
FT                   /experiment="EXISTENCE:direct assay:GO:0005739
FT                   mitochondrion [PMID:20799725]"
FT                   /experiment="EXISTENCE:direct assay:GO:0033743
FT                   peptide-methionine (R)-S-oxide reductase activity
FT                   [PMID:15141092]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0034599
FT                   cellular response to oxidative stress [PMID:11929995]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0033743
FT                   peptide-methionine (R)-S-oxide reductase activity
FT                   [PMID:15141092]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0034599 cellular
FT                   response to oxidative stress [PMID:11929995]"
FT                   /protein_id="DAA07451.1"
FT                   /translation="MNKWSRLYVITVRRTFPGRRNIVLTQYWNKSKKMSDESNDVKWND
FT                   ALTPLQLMVLRDKATERPNTGAYLHTNESGVYHCANCDRPLYSSKAKFDARCGWPAFYE
FT                   EVSPGAITYHRDNSLMPARVEICCARCGGHLGHVFEGEGWKQLLNLPKDTRHCVNSASL
FT                   NLKKD"
FT   gene            63441..64481
FT                   /gene="STE50"
FT                   /locus_tag="YCL032W"
FT   mRNA            63441..64481
FT                   /gene="STE50"
FT                   /locus_tag="YCL032W"
FT                   /product="Ste50p"
FT   CDS_pept        63441..64481
FT                   /codon_start=1
FT                   /gene="STE50"
FT                   /locus_tag="YCL032W"
FT                   /product="Ste50p"
FT                   /note="Adaptor protein for various signaling pathways;
FT                   involved in mating response, invasive/filamentous growth,
FT                   osmotolerance; acts as an adaptor that links G
FT                   protein-associated Cdc42p-Ste20p complex to the effector
FT                   Ste11p to modulate signal transduction"
FT                   /db_xref="GOA:P25344"
FT                   /db_xref="InterPro:IPR000159"
FT                   /db_xref="InterPro:IPR013761"
FT                   /db_xref="InterPro:IPR015316"
FT                   /db_xref="InterPro:IPR029071"
FT                   /db_xref="PDB:1UQV"
FT                   /db_xref="PDB:1Z1V"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25344"
FT                   /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
FT                   [PMID:9742096]"
FT                   /experiment="EXISTENCE:direct assay:GO:0019887 protein
FT                   kinase regulator activity [PMID:10397774]"
FT                   /experiment="EXISTENCE:direct assay:GO:0032093 SAM domain
FT                   binding [PMID:16337230]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0000161
FT                   osmosensory signaling MAPK cascade [PMID:9742096]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000750
FT                   pheromone-dependent signal transduction involved in
FT                   conjugation with cellular fusion [PMID:8793874]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0001402 signal
FT                   transduction involved in filamentous growth [PMID:9738877]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0007232
FT                   osmosensory signaling pathway via Sho1 osmosensor
FT                   [PMID:11370856]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0034605 cellular
FT                   response to heat [PMID:12455951]"
FT                   /experiment="EXISTENCE:physical interaction:GO:0000161
FT                   osmosensory signaling MAPK cascade [PMID:9742096]"
FT                   /protein_id="DAA07452.1"
FT                   /translation="MEDGKQAINEGSNDASPDLDVNGTILMNNEDFSQWSVDDVITWCI
FT                   STLEVEETDPLCQRLRENDIVGDLLPELCLQDCQDLCDGDLNKAIKFKILINKMRDSKL
FT                   EWKDDKTQEDMITVLKNLYTTTSAKLQEFQSQYTRLRMDVLDVMKTSSSSSPINTHGVS
FT                   TTVPSSNNTIIPSSDGVSLSQTDYFDTVHNRQSPSRRESPVTVFRQPSLSHSKSLHKDS
FT                   KNKVPQISTNQSHPSAVSTANTPGPSPNEALKQLRASKEDSCERILKNAMKRHNLADQD
FT                   WRQYVLVICYGDQERLLELNEKPVIIFKNLKQQGLHPAIMLRRRGDFEEVAMMNGSDNV
FT                   TPGGRL"
FT   gene            complement(64675..65568)
FT                   /gene="RRP7"
FT                   /locus_tag="YCL031C"
FT   mRNA            complement(64675..65568)
FT                   /gene="RRP7"
FT                   /locus_tag="YCL031C"
FT                   /product="Rrp7p"
FT   CDS_pept        complement(64675..65568)
FT                   /codon_start=1
FT                   /gene="RRP7"
FT                   /locus_tag="YCL031C"
FT                   /product="Rrp7p"
FT                   /note="Essential protein involved in rRNA processing and
FT                   ribosome biogenesis; protein abundance increases in
FT                   response to DNA replication stress"
FT                   /db_xref="GOA:P25368"
FT                   /db_xref="InterPro:IPR012677"
FT                   /db_xref="InterPro:IPR024326"
FT                   /db_xref="InterPro:IPR040446"
FT                   /db_xref="InterPro:IPR040447"
FT                   /db_xref="PDB:2MBY"
FT                   /db_xref="PDB:4M5D"
FT                   /db_xref="PDB:5WLC"
FT                   /db_xref="PDB:5WYJ"
FT                   /db_xref="PDB:5WYK"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25368"
FT                   /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
FT                   [PMID:14562095]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005730 nucleolus
FT                   [PMID:14562095]"
FT                   /experiment="EXISTENCE:direct assay:GO:0019843 rRNA binding
FT                   [PMID:24130456]"
FT                   /experiment="EXISTENCE:direct assay:GO:0032545 CURI complex
FT                   [PMID:17452446]"
FT                   /experiment="EXISTENCE:direct assay:GO:0034456 UTP-C
FT                   complex [PMID:17515605]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0000028
FT                   ribosomal small subunit assembly [PMID:9271380]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0006364 rRNA
FT                   processing [PMID:9271380]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000028
FT                   ribosomal small subunit assembly [PMID:9271380]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006364 rRNA
FT                   processing [PMID:9271380]"
FT                   /protein_id="DAA07453.1"
FT                   /translation="MGIEDISAMKNGFIVVPFKLPDHKALPKSQEASLHFMFAKRHQSS
FT                   NSNESDCLFLVNLPLLSNIEHMKKFVGQLCGKYDTVSHVEELLYNDEFGLHEVDLSALT
FT                   SDLMSSTDVNEKRYTPRNTALLKFVDAASINNCWNALKKYSNLHAKHPNELFEWTYTTP
FT                   SFTTFVNFYKPLDIDYLKEDIHTHMAIFEQREAQAQEDVQSSIVDEDGFTLVVGKNTKS
FT                   LNSIRKKILNKNPLSKHENKAKPISNIDKKAKKDFYRFQVRERKKQEINQLLSKFKEDQ
FT                   ERIKVMKAKRKFNPYT"
FT   gene            complement(65934..68333)
FT                   /gene="HIS4"
FT                   /locus_tag="YCL030C"
FT   mRNA            complement(65934..68333)
FT                   /gene="HIS4"
FT                   /locus_tag="YCL030C"
FT                   /product="trifunctional histidinol
FT                   dehydrogenase/phosphoribosyl-AMP
FT                   cyclohydrolase/phosphoribosyl-ATP diphosphatase"
FT   CDS_pept        complement(65934..68333)
FT                   /codon_start=1
FT                   /gene="HIS4"
FT                   /locus_tag="YCL030C"
FT                   /product="trifunctional histidinol
FT                   dehydrogenase/phosphoribosyl-AMP
FT                   cyclohydrolase/phosphoribosyl-ATP diphosphatase"
FT                   /EC_number="3.6.1.31"
FT                   /EC_number="3.5.4.19"
FT                   /EC_number="1.1.1.23"
FT                   /note="Multifunctional enzyme containing phosphoribosyl-ATP
FT                   pyrophosphatase; phosphoribosyl-AMP cyclohydrolase, and
FT                   histidinol dehydrogenase activities; catalyzes the second,
FT                   third, ninth and tenth steps in histidine biosynthesis"
FT                   /db_xref="GOA:P00815"
FT                   /db_xref="InterPro:IPR001692"
FT                   /db_xref="InterPro:IPR002496"
FT                   /db_xref="InterPro:IPR008179"
FT                   /db_xref="InterPro:IPR012131"
FT                   /db_xref="InterPro:IPR016161"
FT                   /db_xref="InterPro:IPR016298"
FT                   /db_xref="InterPro:IPR021130"
FT                   /db_xref="InterPro:IPR038019"
FT                   /db_xref="UniProtKB/Swiss-Prot:P00815"
FT                   /experiment="EXISTENCE:direct assay:GO:0004399 histidinol
FT                   dehydrogenase activity [PMID:379004]"
FT                   /experiment="EXISTENCE:direct assay:GO:0004635
FT                   phosphoribosyl-AMP cyclohydrolase activity [PMID:379004]"
FT                   /experiment="EXISTENCE:direct assay:GO:0004636
FT                   phosphoribosyl-ATP diphosphatase activity [PMID:379004]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
FT                   [PMID:14562095]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000105
FT                   histidine biosynthetic process
FT                   [PMID:14190241|PMID:5919326]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0004399
FT                   histidinol dehydrogenase activity [PMID:5919326]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0004635
FT                   phosphoribosyl-AMP cyclohydrolase activity [PMID:5919326]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0004636
FT                   phosphoribosyl-ATP diphosphatase activity [PMID:5919326]"
FT                   /protein_id="DAA07454.1"
FT                   /translation="MVLPILPLIDDLASWNSKKEYVSLVGQVLLDGSSLSNEEILQFSK
FT                   EEEVPLVALSLPSGKFSDDEIIAFLNNGVSSLFIASQDAKTAEHLVEQLNVPKERVVVE
FT                   ENGVFSNQFMVKQKFSQDKIVSIKKLSKDMLTKEVLGEVRTDRPDGLYTTLVVDQYERC
FT                   LGLVYSSKKSIAKAIDLGRGVYYSRSRNEIWIKGETSGNGQKLLQISTDCDSDALKFIV
FT                   EQENVGFCHLETMSCFGEFKHGLVGLESLLKQRLQDAPEESYTRRLFNDSALLDAKIKE
FT                   EAEELTEAKGKKELSWEAADLFYFALAKLVANDVSLKDVENNLNMKHLKVTRRKGDAKP
FT                   KFVGQPKAEEEKLTGPIHLDVVKASDKVGVQKALSRPIQKTSEIMHLVNPIIENVRDKG
FT                   NSALLEYTEKFDGVKLSNPVLNAPFPEEYFEGLTEEMKEALDLSIENVRKFHAAQLPTE
FT                   TLEVETQPGVLCSRFPRPIEKVGLYIPGGTAILPSTALMLGVPAQVAQCKEIVFASPPR
FT                   KSDGKVSPEVVYVAEKVGASKIVLAGGAQAVAAMAYGTETIPKVDKILGPGNQFVTAAK
FT                   MYVQNDTQALCSIDMPAGPSEVLVIADEDADVDFVASDLLSQAEHGIDSQVILVGVNLS
FT                   EKKIQEIQDAVHNQALQLPRVDIVRKCIAHSTIVLCDGYEEALEMSNQYAPEHLILQIA
FT                   NANDYVKLVDNAGSVFVGAYTPESCGDYSSGTNHTLPTYGYARQYSGANTATFQKFITA
FT                   QNITPEGLENIGRAVMCVAKKEGLDGHRNAVKIRMSKLGLIPKDFQ"
FT   gene            complement(68599..69921)
FT                   /gene="BIK1"
FT                   /gene_synonym="ARM5"
FT                   /gene_synonym="PAC14"
FT                   /locus_tag="YCL029C"
FT   mRNA            complement(68599..69921)
FT                   /gene="BIK1"
FT                   /gene_synonym="ARM5"
FT                   /gene_synonym="PAC14"
FT                   /locus_tag="YCL029C"
FT                   /product="Bik1p"
FT   CDS_pept        complement(68599..69921)
FT                   /codon_start=1
FT                   /gene="BIK1"
FT                   /gene_synonym="ARM5"
FT                   /gene_synonym="PAC14"
FT                   /locus_tag="YCL029C"
FT                   /product="Bik1p"
FT                   /note="Microtubule-associated protein; component of the
FT                   interface between microtubules and kinetochore, involved in
FT                   sister chromatid separation; essential in polyploid cells
FT                   but not in haploid or diploid cells; ortholog of mammalian
FT                   CLIP-170"
FT                   /db_xref="GOA:P11709"
FT                   /db_xref="InterPro:IPR000938"
FT                   /db_xref="InterPro:IPR036859"
FT                   /db_xref="PDB:6FC5"
FT                   /db_xref="PDB:6FC6"
FT                   /db_xref="UniProtKB/Swiss-Prot:P11709"
FT                   /experiment="EXISTENCE:direct assay:GO:0000776 kinetochore
FT                   [PMID:11756471]"
FT                   /experiment="EXISTENCE:direct assay:GO:0000778 condensed
FT                   nuclear chromosome kinetochore [PMID:11511347]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005816 spindle pole
FT                   body [PMID:2277073]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005819 spindle
FT                   [PMID:2277073]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005876 spindle
FT                   microtubule [PMID:11511347]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005938 cell cortex
FT                   [PMID:11511347]"
FT                   /experiment="EXISTENCE:direct assay:GO:0008017 microtubule
FT                   binding [PMID:9398684]"
FT                   /experiment="EXISTENCE:direct assay:GO:0031115 negative
FT                   regulation of microtubule polymerization [PMID:20392838]"
FT                   /experiment="EXISTENCE:direct assay:GO:0035371 microtubule
FT                   plus-end [PMID:20392838]"
FT                   /experiment="EXISTENCE:direct assay:GO:0043332 mating
FT                   projection tip [PMID:16380440]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0000022
FT                   mitotic spindle elongation [PMID:7559759]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0030543
FT                   2-micrometer plasmid partitioning [PMID:28004422]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000742
FT                   karyogamy involved in conjugation with cellular fusion
FT                   [PMID:2277073]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000743 nuclear
FT                   migration involved in conjugation with cellular fusion
FT                   [PMID:16380440]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0030543
FT                   2-micrometer plasmid partitioning [PMID:28004422]"
FT                   /protein_id="DAA07455.1"
FT                   /translation="MDRYQRKIGCFIQIPNLGRGQLKYVGPVDTKAGMFAGVDLLANIG
FT                   KNDGSFMGKKYFQTEYPQSGLFIQLQKVASLIEKASISQTSRRTTMEPLSIPKNRSIVR
FT                   LTNQFSPMDDPKSPTPMRSFRITSRHSGNQQSMDQEASDHHQQQEFGYDNREDRMEVDS
FT                   ILSSDRKANHNTTSDWKPDNGHMNDLNSSEVTIELREAQLTIEKLQRKQLHYKRLLDDQ
FT                   RMVLEEVQPTFDRYEATIQEREKEIDHLKQQLELERRQQAKQKQFFDAENEQLLAVVSQ
FT                   LHEEIKENEERNLSHNQPTGANEDVELLKKQLEQLRNIEDQFELHKTKWAKEREQLKMH
FT                   NDSLSKEYQNLSKELFLTKPQDSSSEEVASLTKKLEEANEKIKQLEQAQAQTAVESLPI
FT                   FDPPAPVDTTAGRQQWCEHCDTMGHNTAECPHHNPDNQQFF"
FT   gene            70150..71367
FT                   /gene="RNQ1"
FT                   /locus_tag="YCL028W"
FT   mRNA            70150..71367
FT                   /gene="RNQ1"
FT                   /locus_tag="YCL028W"
FT                   /product="prion domain-containing protein RNQ1"
FT   CDS_pept        70150..71367
FT                   /codon_start=1
FT                   /gene="RNQ1"
FT                   /locus_tag="YCL028W"
FT                   /product="prion domain-containing protein RNQ1"
FT                   /note="[PIN(+)] prion; an infectious protein conformation
FT                   that is generally an ordered protein aggregate"
FT                   /db_xref="GOA:P25367"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25367"
FT                   /experiment="EXISTENCE:direct assay:GO:0005829 cytosol
FT                   [PMID:11511345]"
FT                   /protein_id="DAA07456.1"
FT                   /translation="MDTDKLISEAESHFSQGNHAEAVAKLTSAAQSNPNDEQMSTIESL
FT                   IQKIAGYVMDNRSGGSDASQDRAAGGGSSFMNTLMADSKGSSQTQLGKLALLATVMTHS
FT                   SNKGSSNRGFDVGTVMSMLSGSGGGSQSMGASGLAALASQFFKSGNNSQGQGQGQGQGQ
FT                   GQGQGQGQGSFTALASLASSFMNSNNNNQQGQNQSSGGSSFGALASMASSFMHSNNNQN
FT                   SNNSQQGYNQSYQNGNQNSQGYNNQQYQGGNGGYQQQQGQSGGAFSSLASMAQSYLGGG
FT                   QTQSNQQQYNQQGQNNQQQYQQQGQNYQHQQQGQQQQQGHSSSFSALASMASSYLGNNS
FT                   NSNSSYGGQQQANEYGRPQQNGQQQSNEYGRPQYGGNQNSNGQHESFNFSGNFSQQNNN
FT                   GNQNRY"
FT   gene            71803..73341
FT                   /gene="FUS1"
FT                   /locus_tag="YCL027W"
FT   mRNA            71803..73341
FT                   /gene="FUS1"
FT                   /locus_tag="YCL027W"
FT                   /product="Fus1p"
FT   CDS_pept        71803..73341
FT                   /codon_start=1
FT                   /gene="FUS1"
FT                   /locus_tag="YCL027W"
FT                   /product="Fus1p"
FT                   /note="Membrane protein localized to the shmoo tip;
FT                   required for cell fusion; expression regulated by mating
FT                   pheromone; proposed to coordinate signaling, fusion, and
FT                   polarization events required for fusion; potential Cdc28p
FT                   substrate"
FT                   /db_xref="GOA:P11710"
FT                   /db_xref="InterPro:IPR001452"
FT                   /db_xref="InterPro:IPR035521"
FT                   /db_xref="InterPro:IPR036028"
FT                   /db_xref="UniProtKB/Swiss-Prot:P11710"
FT                   /experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
FT                   reticulum [PMID:26928762]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005887 integral
FT                   component of plasma membrane [PMID:2690078]"
FT                   /experiment="EXISTENCE:direct assay:GO:0043332 mating
FT                   projection tip [PMID:12374868|PMID:3302672|PMID:19053807]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0000755
FT                   cytogamy [PMID:3302672]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000755 cytogamy
FT                   [PMID:3302672|PMID:3313002]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0031385
FT                   regulation of termination of mating projection growth
FT                   [PMID:14734532]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0032065 cortical
FT                   protein anchoring [PMID:18474625]"
FT                   /protein_id="DAA07457.1"
FT                   /translation="MVATIMQTTTTVLTTVAAMSTTLASNYISSQASSSTSVTTVTTIA
FT                   TSIRSTPSNLLFSNVAAQPKSSSASTIGLSIGLPIGIFCFGLLILLCYFYLKRNSVSIS
FT                   NPPMSATIPREEEYCRRTNWFSRLFWQSKCEDQNSYSNRDIEKYNDTQWTSGDNMSSKI
FT                   QYKISKPIIPQHILTPKKTVKNPYAWSGKNISLDPKVNEMEEEKVVDAFLYTKPPNIVH
FT                   IESSMPSYNDLPSQKTVSSKKTALKTSEKWSYESPLSRWFLRGSTYFKDYGLSKTSLKT
FT                   PTGAPQLKQMKMLSRISKGYFNESDIMPDERSPILEYNNTPLDANDSVNNLGNTTPDSQ
FT                   ITSYRNNNIDLITARPHSVIYGTTAQQTLETNFNDHHDCNKSTEKHELIIPTPSKPLKK
FT                   RKKRRQSKMYQHLQHLSRSKPLPLTPNSKYNGEASVQLGKTYTVIQDYEPRLTDEIRIS
FT                   LGEKVKILATHTDGWCLVEKCNTQKGSIHVSVDDKRYLNEDRGIVPGDCLQEYD"
FT   gene            complement(73405..73986)
FT                   /gene="HBN1"
FT                   /gene_synonym="YCL027C-A"
FT                   /locus_tag="YCL026C-B"
FT   mRNA            complement(73405..73986)
FT                   /gene="HBN1"
FT                   /gene_synonym="YCL027C-A"
FT                   /locus_tag="YCL026C-B"
FT                   /product="putative nitroreductase"
FT   CDS_pept        complement(73405..73986)
FT                   /codon_start=1
FT                   /gene="HBN1"
FT                   /gene_synonym="YCL027C-A"
FT                   /locus_tag="YCL026C-B"
FT                   /product="putative nitroreductase"
FT                   /note="hypothetical protein; similar to bacterial
FT                   nitroreductases; green fluorescent protein (GFP)-fusion
FT                   protein localizes to the cytoplasm and nucleus; protein
FT                   becomes insoluble upon intracellular iron depletion;
FT                   protein abundance increases in response to DNA replication
FT                   stress"
FT                   /db_xref="GOA:Q96VH4"
FT                   /db_xref="InterPro:IPR000415"
FT                   /db_xref="InterPro:IPR029479"
FT                   /db_xref="InterPro:IPR033877"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q96VH4"
FT                   /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
FT                   [PMID:14562095]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
FT                   [PMID:14562095]"
FT                   /protein_id="DAA07458.1"
FT                   /translation="MSAVATYLKTLTARRTIYALKPELPGEITINDIQSVVQTIIKETP
FT                   TAFNSQPNRAVILTGETHKKVWDEVTKAIESPAGQKRPASARDEAFGSVIFFTDDKVTE
FT                   KLKADFPAYAAAFPSFADHTSGAAQINSWVALEAMGLGGHLQHYNGYIKAALPSKIPES
FT                   WTVQAQLVFGTPAAPPGEKTYIKNDVEIFN"
FT   rep_origin      74458..74677
FT                   /note="ARS306; Early-firing autonomously replicating
FT                   sequence on Chromosome III"
FT   gene            complement(74704..75285)
FT                   /gene="FRM2"
FT                   /gene_synonym="YCLX08C"
FT                   /locus_tag="YCL026C-A"
FT   mRNA            complement(74704..75285)
FT                   /gene="FRM2"
FT                   /gene_synonym="YCLX08C"
FT                   /locus_tag="YCL026C-A"
FT                   /product="type II nitroreductase"
FT   CDS_pept        complement(74704..75285)
FT                   /codon_start=1
FT                   /gene="FRM2"
FT                   /gene_synonym="YCLX08C"
FT                   /locus_tag="YCL026C-A"
FT                   /product="type II nitroreductase"
FT                   /note="Type II nitroreductase, using NADH as reductant;
FT                   mutants are defective in fatty acid mediated repression of
FT                   genes involved in fatty acid biosynthesis indicative of a
FT                   role in lipid signaling; involved in the oxidative stress
FT                   response; transcription induction by cadmium and selenite
FT                   indicates a possible role in the metal stress response;
FT                   expression induced in cells treated with the mycotoxin
FT                   patulin"
FT                   /db_xref="GOA:P37261"
FT                   /db_xref="InterPro:IPR000415"
FT                   /db_xref="InterPro:IPR029479"
FT                   /db_xref="InterPro:IPR033877"
FT                   /db_xref="PDB:4URP"
FT                   /db_xref="UniProtKB/Swiss-Prot:P37261"
FT                   /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
FT                   [PMID:14562095]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
FT                   [PMID:14562095]"
FT                   /experiment="EXISTENCE:direct assay:GO:0016657
FT                   oxidoreductase activity, acting on NAD(P)H, nitrogenous
FT                   group as acceptor [PMID:22687599]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0034599
FT                   cellular response to oxidative stress [PMID:19904831]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0034599 cellular
FT                   response to oxidative stress [PMID:19904831]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0045922 negative
FT                   regulation of fatty acid metabolic process [PMID:8701605]"
FT                   /protein_id="DAA07459.1"
FT                   /translation="MSPTGNYLNAITNRRTIYNLKPELPQGVGLDDVKRTVHVILKNTP
FT                   TAFNSQVNRAVIIVGDTHKRIWDAVASAMPTAEAKKRPESCRDEAYGSVIFFTDEGPTE
FT                   KLQRDFPALAAAFPTCAAHTTGAVQIQSWTALELLGLGANLQHYNDYVKSALPQDVPIA
FT                   WTVQSQLVFGVPTALPEEKTFINNVINVYH"
FT   gene            complement(76018..77919)
FT                   /gene="AGP1"
FT                   /gene_synonym="YCC5"
FT                   /locus_tag="YCL025C"
FT   mRNA            complement(76018..77919)
FT                   /gene="AGP1"
FT                   /gene_synonym="YCC5"
FT                   /locus_tag="YCL025C"
FT                   /product="amino acid transporter AGP1"
FT   CDS_pept        complement(76018..77919)
FT                   /codon_start=1
FT                   /gene="AGP1"
FT                   /gene_synonym="YCC5"
FT                   /locus_tag="YCL025C"
FT                   /product="amino acid transporter AGP1"
FT                   /note="Low-affinity amino acid permease with broad
FT                   substrate range; involved in uptake of asparagine,
FT                   glutamine, and other amino acids; expression regulated by
FT                   SPS plasma membrane amino acid sensor system
FT                   (Ssy1p-Ptr3p-Ssy5p); AGP1 has a paralog, GNP1, that arose
FT                   from the whole genome duplication"
FT                   /db_xref="GOA:P25376"
FT                   /db_xref="InterPro:IPR002293"
FT                   /db_xref="InterPro:IPR004762"
FT                   /db_xref="InterPro:IPR004840"
FT                   /db_xref="InterPro:IPR004841"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25376"
FT                   /experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
FT                   reticulum [PMID:26928762]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005886 plasma
FT                   membrane [PMID:27226538]"
FT                   /experiment="EXISTENCE:direct assay:GO:0006865 amino acid
FT                   transport [PMID:10654085]"
FT                   /experiment="EXISTENCE:direct assay:GO:0015171 amino acid
FT                   transmembrane transporter activity [PMID:10654085]"
FT                   /experiment="EXISTENCE:direct assay:GO:0055085
FT                   transmembrane transport [PMID:10654085]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0015193
FT                   L-proline transmembrane transporter activity
FT                   [PMID:14968425]"
FT                   /protein_id="DAA07460.1"
FT                   /translation="MSSSKSLYELKDLKNSSTEIHATGQDNEIEYFETGSNDRPSSQPH
FT                   LGYEQHNTSAVRRFFDSFKRADQGPQDEVEATQMNDLTSAISPSSRQAQELEKNESSDN
FT                   IGANTGHKSDSLKKTIQPRHVLMIALGTGIGTGLLVGNGTALVHAGPAGLLIGYAIMGS
FT                   ILYCIIQACGEMALVYSNLTGGYNAYPSFLVDDGFGFAVAWVYCLQWLCVCPLELVTAS
FT                   MTIKYWTTSVNPDVFVIIFYVLVITINIFGARGYAEAEFFFNCCKILMMTGFFILGIII
FT                   DVGGAGNDGFIGGKYWHDPGAFNGKHAIDRFKGVAATLVTAAFAFGGSEFIAITTAEQS
FT                   NPRKAIPGAAKQMIYRILFLFLATIILLGFLVPYNSDQLLGSTGGGTKASPYVIAVASH
FT                   GVRVVPHFINAVILLSVLSMANSSFYSSARLFLTLSEQGYAPKVFSYIDRAGRPLIAMG
FT                   VSALFAVIAFCAASPKEEQVFTWLLAISGLSQLFTWTAICLSHLRFRRAMKVQGRSLGE
FT                   LGFKSQTGVWGSAYACIMMILILIAQFWVAIAPIGEGKLDAQAFFENYLAMPILIALYV
FT                   GYKVWHKDWKLFIRADKIDLDSHRQIFDEELIKQEDEEYRERLRNGPYWKRVVAFWC"
FT   gene            79162..82275
FT                   /gene="KCC4"
FT                   /locus_tag="YCL024W"
FT   mRNA            79162..82275
FT                   /gene="KCC4"
FT                   /locus_tag="YCL024W"
FT                   /product="serine/threonine protein kinase"
FT   CDS_pept        79162..82275
FT                   /codon_start=1
FT                   /gene="KCC4"
FT                   /locus_tag="YCL024W"
FT                   /product="serine/threonine protein kinase"
FT                   /EC_number="2.7.11.1"
FT                   /note="Protein kinase of the bud neck involved in the
FT                   septin checkpoint; associates with septin proteins,
FT                   negatively regulates Swe1p by phosphorylation, shows
FT                   structural homology to bud neck kinases Gin4p and Hsl1p;
FT                   KCC4 has a paralog, GIN4, that arose from the whole genome
FT                   duplication"
FT                   /db_xref="GOA:P25389"
FT                   /db_xref="InterPro:IPR000719"
FT                   /db_xref="InterPro:IPR008271"
FT                   /db_xref="InterPro:IPR011009"
FT                   /db_xref="InterPro:IPR017441"
FT                   /db_xref="InterPro:IPR031850"
FT                   /db_xref="PDB:3OSM"
FT                   /db_xref="PDB:3OST"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25389"
FT                   /experiment="EXISTENCE:direct assay:GO:0000131 incipient
FT                   cellular bud site [PMID:15901837]"
FT                   /experiment="EXISTENCE:direct assay:GO:0004672 protein
FT                   kinase activity [PMID:16319894]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005935 cellular bud
FT                   neck [PMID:15282802|PMID:9925642]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005940 septin ring
FT                   [PMID:15901837]"
FT                   /experiment="EXISTENCE:direct assay:GO:0006468 protein
FT                   phosphorylation [PMID:16319894]"
FT                   /experiment="EXISTENCE:direct assay:GO:0032174 cellular bud
FT                   neck septin collar [PMID:15901837]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000921 septin
FT                   ring assembly [PMID:9925642]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0007117 budding
FT                   cell bud growth [PMID:9925642]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0044879
FT                   morphogenesis checkpoint [PMID:9925642]"
FT                   /protein_id="DAA07461.1"
FT                   /translation="MTVANTETHSAAKPSSTIGPWKLGETLGFGSTGKVQLAQHERTGH
FT                   RTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYL
FT                   ILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSF
FT                   YNIKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLT
FT                   GRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQRIKIRDILS
FT                   HPLLKKYQTIKDSKSIKDLPRENTYLYPLADSNNHTSASIDDSILQNLVVLWHGRHADD
FT                   IVSKLKENGTNKEKILYALLYRFKLDSVRGSNKKNRNKIKKTKKNKRSSTLSSSSSLLL
FT                   NNRSIQSTPRRRTSKRHSREFSSSRKRSSFLLSSNPTDSSPIPLRSSKRITHINVASAN
FT                   TQATPSGVPNPHKRNSKKRSSKRLSYMPNTKRSSLTSKSLSNFTNLIDDDDWEYIEKDA
FT                   KRTSSNFATLIDEIFEPEKFELAKREKAELQRKVQEAKRQSVNAQKINEDEFGSEVSDG
FT                   MKELKKINDKVSSPLINYEFSQQELLQDIDTLLTNRYQLSSYTRPISRLDPGLTPVTET
FT                   LPNNLKEKTALLQDTEKKIIETIRRSKFLGSLLNVRGGLSPGKSELAPIEESPIVSTTP
FT                   LIYNDRMEPRRISDVEVPHFTRKSKHFTTANNRRSVLSLYAKDSIKDLNEFLIKEDPDL
FT                   PPQGSTDNESRSEDPEIAESITDSRNIQYDEDDSKDGDNVNNDNILSDFPQGVGISQEY
FT                   DMKDKNPNQSPISKSAEPTLVVKLPSLSSFQGKNASGLGLYQREPSKVTLPSLTSNNSS
FT                   VGENIEDGAEKGTESEKIAASLSDDDLKEDNDKKDNDTVNAPTTVKKPPNSVLLKKFSK
FT                   GKILELEIHAKIPEKRLYEGLHKLLEGWKQYGLKNLVFNITNMIITGKLVNDSILFLRS
FT                   TLFEIMVLPNGDGRSLIKFNKKTGSTKTLTKLATEIQIILQKEGVLDK"
FT   gene            complement(82462..82533)
FT                   /locus_tag="tE(UUC)C"
FT   tRNA            complement(82462..82533)
FT                   /locus_tag="tE(UUC)C"
FT                   /product="tRNA-Glu"
FT                   /note="tE(UUC)C; Glutamine tRNA (tRNA-Glu), predicted by
FT                   tRNAscan-SE analysis; thiolation of uridine at wobble
FT                   position (34) requires Ncs6p"
FT                   /experiment="EXISTENCE:curator inference:GO:0005829 cytosol
FT                   [PMID:9023104]"
FT                   /experiment="EXISTENCE:curator inference:GO:0006414
FT                   translational elongation [PMID:9023104]"
FT   repeat_region   82700..83036
FT                   /rpt_type=LONG_TERMINAL_REPEAT
FT                   /note="Ty1 LTR"
FT   repeat_region   complement(83055..83194)
FT                   /rpt_type=LONG_TERMINAL_REPEAT
FT                   /note="Ty1 LTR"
FT   gene            83620..83997
FT                   /locus_tag="YCL021W-A"
FT   mRNA            83620..83997
FT                   /locus_tag="YCL021W-A"
FT                   /product="hypothetical protein"
FT   CDS_pept        83620..83997
FT                   /codon_start=1
FT                   /locus_tag="YCL021W-A"
FT                   /product="hypothetical protein"
FT                   /note="hypothetical protein; SWAT-GFP and mCherry fusion
FT                   proteins localize to the vacuole"
FT                   /db_xref="GOA:Q96VH3"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q96VH3"
FT                   /experiment="EXISTENCE:direct assay:GO:0000324 fungal-type
FT                   vacuole [PMID:26928762]"
FT                   /protein_id="DAA07462.1"
FT                   /translation="MVLTDAEELRSPVITSDMSFFDLESNHSSDSVHLLCEKYTHKLPI
FT                   ESESQTTFRLAPTKQRLYRQSTLYVPLSLKQRVFLFTERVKSIWAGLPRCKPNKYFKVA
FT                   FALAVLTPLAIWIFYIDFRVH"
FT   repeat_region   84069..84294
FT                   /rpt_type=LONG_TERMINAL_REPEAT
FT                   /note="Ty1 LTR"
FT   repeat_region   84295..84626
FT                   /rpt_type=LONG_TERMINAL_REPEAT
FT                   /note="Ty1 LTR"
FT   repeat_region   84630..84718
FT                   /rpt_type=LONG_TERMINAL_REPEAT
FT                   /note="Ty1 LTR"
FT   mobile_element  84811..90769
FT                   /mobile_element_type="retrotransposon:YCLWTy2-1"
FT                   /note="YCLWTy2-1; Ty2 element, LTR retrotransposon of the
FT                   Copia (Pseudoviridae) group; contains co-transcribed genes
FT                   TYA Gag and TYB Pol, encoding proteins involved in
FT                   structure and function of virus-like particles, flanked by
FT                   two direct repeats"
FT   repeat_region   84811..85142
FT                   /rpt_type=LONG_TERMINAL_REPEAT
FT                   /note="Ty2 LTR"
FT   gene            85102..90415
FT                   /locus_tag="YCL019W"
FT   mRNA            85102..90415
FT                   /locus_tag="YCL019W"
FT                   /product="gag-pol fusion protein"
FT   CDS_pept        join(85102..86391,86393..90415)
FT                   /codon_start=1
FT                   /ribosomal_slippage
FT                   /locus_tag="YCL019W"
FT                   /product="gag-pol fusion protein"
FT                   /EC_number="2.7.7.49"
FT                   /EC_number="3.1.26.4"
FT                   /EC_number="2.7.7.7"
FT                   /note="Retrotransposon TYA Gag and TYB Pol genes;
FT                   transcribed/translated as one unit; polyprotein is
FT                   processed to make a nucleocapsid-like protein (Gag),
FT                   reverse transcriptase (RT), protease (PR), and integrase
FT                   (IN); similar to retroviral genes"
FT                   /db_xref="GOA:P25384"
FT                   /db_xref="InterPro:IPR001584"
FT                   /db_xref="InterPro:IPR012337"
FT                   /db_xref="InterPro:IPR013103"
FT                   /db_xref="InterPro:IPR015820"
FT                   /db_xref="InterPro:IPR025724"
FT                   /db_xref="InterPro:IPR036397"
FT                   /db_xref="InterPro:IPR039537"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25384"
FT                   /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
FT                   [PMID:9448009]"
FT                   /protein_id="DAA07463.1"
FT                   /translation="MESQQLHQNPRSLHGSAYASVTSKEVPSNQDPLAVSASNLPEFDR
FT                   DSTKVNSQQETTPGTSAVPENHHHVSPQPASVPPPQNGQYQQHGMMTPNKAMASNWAHY
FT                   QQPSMMTCSHYQTSPAYYQPDPHYPLPQYIPPLSTSSPDPIDSQNQHSEVPQAETKVRN
FT                   NVLPPHTLTSEENFSTWVKFYIRFLKNSNLGDIIPNDQGEIKRQMTYEEHAYIYNTFQA
FT                   FAPFHLLPTWVKQILEINYADILTVLCKSVSKMQTNNQELKDWIALANLEYDGSTSADT
FT                   FEITVSTIIQRLKENNINVSDRLACQLILKGLSGDFKYLRNQYRTKTNMKLSQLFAEIQ
FT                   LIYDENKIMNLNKPSQYKQHSEYKNVSRTSPNTTNTKVTTRNYQRTNSSKPRAAKAHNI
FT                   ATSSKFSRVNNDHINESTVSSQYLSDDNELSLGQQQKESKPTHTIDSNDELPDHLLIDS
FT                   GASQTLVRSAHYLHHATPNSEINIVDAQKQDIPINAIGNLHFNFQNGTKTSIKALHTPN
FT                   IAYDLLSLSELANQNITACFTRNTLERSDGTVLAPIVKHGDFYWLSKKYLIPSHISKLT
FT                   INNVNKSKSVNKYPYPLIHRMLGHANFRSIQKSLKKNAVTYLKESDIEWSNASTYQCPD
FT                   CLIGKSTKHRHVKGSRLKYQESYEPFQYLHTDIFGPVHHLPKSAPSYFISFTDEKTRFQ
FT                   WVYPLHDRREESILNVFTSILAFIKNQFNARVLVIQMDRGSEYTNKTLHKFFTNRGITA
FT                   CYTTTADSRAHGVAERLNRTLLNDCRTLLHCSGLPNHLWFSAVEFSTIIRNSLVSPKND
FT                   KSARQHAGLAGLDITTILPFGQPVIVNNHNPDSKIHPRGIPGYALHPSRNSYGYIIYLP
FT                   SLKKTVDTTNYVILQDKQSKLDQFNYDTLTFDDDLNRLTAHNQSFIEQNETEQSYDQNT
FT                   ESDHDYQSEIEINSDPLVNDFSSQSINPLQLDKEPVQKVRAPKEVDADISEYNILPSPV
FT                   RSRTPHIINKESTEMGGTVESDTTSPRHSSTFTARNQKRPGSPNDMIDLTSQDRVNYGL
FT                   ENIKTTRLGGTEEPYIQRNSDTNIKYRTTNSTPSIDDRSSNSESTTPIISIETKAVCDN
FT                   TPSIDTDPPEYRSSDHATPNIMPDKSSKNVTADSILDDLPLPDLTHQSPTDTSDVSKDI
FT                   PHIHSRQTNSSLGGMDDSNVLTTTKSKKRSLEDNETEIEVSRDTWNNKNMRSLEPPRSK
FT                   KRINLIAAIKGVKSIKPVRTTLRYDEAITYNKDNKEKDRYVEAYHKEISQLLKMNTWDT
FT                   NKYYDRNDIDPKKVINSMFIFNKKRDGTHKARFVARGDIQHPDTYDSDMQSNTVHHYAL
FT                   MTSLSIALDNDYYITQLDISSAYLYADIKEELYIRPPPHLGLNDKLLRLRKSLYGLKQS
FT                   GANWYETIKSYLINCCDMQEVRGWSCVFKNSQVTICLFVDDMILFSKDLNANKKIITTL
FT                   KKQYDTKIINLGESDNEIQYDILGLEIKYQRSKYMKLGMEKSLTEKLPKLNVPLNPKGK
FT                   KLRAPGQPGHYIDQDELEIDEDEYKEKVHEMQKLIGLASYVGYKFRFDLLYYINTLAQH
FT                   ILFPSRQVLDMTYELIQFMWDTRDKQLIWHKNKPTKPDNKLVAISDASYGNQPYYKSQI
FT                   GNIFLLNGKVIGGKSTKASLTCTSTTEAEIHAVSEAIPLLNNLSHLVQELNKKPIIKGL
FT                   LTDSRSTISIIKSTNEEKFRNRFFGTKAMRLRDEVSGNNLYVYYIETKKNIADVMTKPL
FT                   PIKTFKLLTNKWIH"
FT   gene            85102..86418
FT                   /locus_tag="YCL020W"
FT   mRNA            85102..86418
FT                   /locus_tag="YCL020W"
FT                   /product="gag protein"
FT   CDS_pept        85102..86418
FT                   /codon_start=1
FT                   /locus_tag="YCL020W"
FT                   /product="gag protein"
FT                   /note="Retrotransposon TYA Gag gene co-transcribed with TYB
FT                   Pol; translated as TYA or TYA-TYB polyprotein; Gag is a
FT                   nucleocapsid protein that is the structural constituent of
FT                   virus-like particles (VLPs); similar to retroviral Gag"
FT                   /db_xref="GOA:P25383"
FT                   /db_xref="InterPro:IPR015820"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25383"
FT                   /protein_id="DAA07464.1"
FT                   /translation="MESQQLHQNPRSLHGSAYASVTSKEVPSNQDPLAVSASNLPEFDR
FT                   DSTKVNSQQETTPGTSAVPENHHHVSPQPASVPPPQNGQYQQHGMMTPNKAMASNWAHY
FT                   QQPSMMTCSHYQTSPAYYQPDPHYPLPQYIPPLSTSSPDPIDSQNQHSEVPQAETKVRN
FT                   NVLPPHTLTSEENFSTWVKFYIRFLKNSNLGDIIPNDQGEIKRQMTYEEHAYIYNTFQA
FT                   FAPFHLLPTWVKQILEINYADILTVLCKSVSKMQTNNQELKDWIALANLEYDGSTSADT
FT                   FEITVSTIIQRLKENNINVSDRLACQLILKGLSGDFKYLRNQYRTKTNMKLSQLFAEIQ
FT                   LIYDENKIMNLNKPSQYKQHSEYKNVSRTSPNTTNTKVTTRNYQRTNSSKPRAAKAHNI
FT                   ATSSKFSRVNNDHINESTVSSQYLSDDNELSLRPATERI"
FT   repeat_region   90438..90769
FT                   /rpt_type=LONG_TERMINAL_REPEAT
FT                   /note="Ty2 LTR"
FT   gene            90859..90972
FT                   /gene="SUP53"
FT                   /locus_tag="tL(CAA)C"
FT   tRNA            90859..90972
FT                   /gene="SUP53"
FT                   /locus_tag="tL(CAA)C"
FT                   /product="tRNA-Leu"
FT                   /note="tL(CAA)C; Leucine tRNA (tRNA-Leu), predicted by
FT                   tRNAscan-SE analysis; can mutate to suppress amber nonsense
FT                   mutations"
FT                   /experiment="EXISTENCE:curator inference:GO:0005829 cytosol
FT                   [PMID:9023104]"
FT                   /experiment="EXISTENCE:curator inference:GO:0006414
FT                   translational elongation [PMID:9023104]"
FT   gene            91324..92418
FT                   /gene="LEU2"
FT                   /locus_tag="YCL018W"
FT   mRNA            91324..92418
FT                   /gene="LEU2"
FT                   /locus_tag="YCL018W"
FT                   /product="3-isopropylmalate dehydrogenase"
FT   CDS_pept        91324..92418
FT                   /codon_start=1
FT                   /gene="LEU2"
FT                   /locus_tag="YCL018W"
FT                   /product="3-isopropylmalate dehydrogenase"
FT                   /EC_number="1.1.1.85"
FT                   /note="Beta-isopropylmalate dehydrogenase (IMDH); catalyzes
FT                   the third step in the leucine biosynthesis pathway; can
FT                   additionally catalyze the conversion of beta-ethylmalate
FT                   into alpha-ketovalerate"
FT                   /db_xref="GOA:P04173"
FT                   /db_xref="InterPro:IPR004429"
FT                   /db_xref="InterPro:IPR019818"
FT                   /db_xref="InterPro:IPR024084"
FT                   /db_xref="UniProtKB/Swiss-Prot:P04173"
FT                   /experiment="EXISTENCE:direct assay:GO:0003862
FT                   3-isopropylmalate dehydrogenase activity [PMID:3071718]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005829 cytosol
FT                   [PMID:4355481]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0003862
FT                   3-isopropylmalate dehydrogenase activity [PMID:6297759]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006097
FT                   glyoxylate cycle [PMID:23642236]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0009098 leucine
FT                   biosynthetic process [PMID:6297759]"
FT                   /protein_id="DAA07465.1"
FT                   /translation="MSAPKKIVVLPGDHVGQEITAEAIKVLKAISDVRSNVKFDFENHL
FT                   IGGAAIDATGVPLPDEALEASKKADAVLLGAVGGPKWGTGSVRPEQGLLKIRKELQLYA
FT                   NLRPCNFASDSLLDLSPIKPQFAKGTDFVVVRELVGGIYFGKRKEDDGDGVAWDSEQYT
FT                   VPEVQRITRMAAFMALQHEPPLPIWSLDKANVLASSRLWRKTVEETIKNEFPTLKVQHQ
FT                   LIDSAAMILVKNPTHLNGIIITSNMFGDIISDEASVIPGSLGLLPSASLASLPDKNTAF
FT                   GLYEPCHGSAPDLPKNKVNPIATILSAAMMLKLSLNLPEEGKAIEDAVKKVLDAGIRTG
FT                   DLGGSNSTTEVGDAVAEEVKKILA"
FT   gene            complement(92777..94270)
FT                   /gene="NFS1"
FT                   /gene_synonym="SPL1"
FT                   /locus_tag="YCL017C"
FT   mRNA            complement(92777..94270)
FT                   /gene="NFS1"
FT                   /gene_synonym="SPL1"
FT                   /locus_tag="YCL017C"
FT                   /product="cysteine desulfurase"
FT   CDS_pept        complement(92777..94270)
FT                   /codon_start=1
FT                   /gene="NFS1"
FT                   /gene_synonym="SPL1"
FT                   /locus_tag="YCL017C"
FT                   /product="cysteine desulfurase"
FT                   /EC_number="2.8.1.7"
FT                   /note="Cysteine desulfurase; involved in iron-sulfur
FT                   cluster (Fe/S) biogenesis and in thio-modification of
FT                   mitochondrial and cytoplasmic tRNAs; essential protein
FT                   located predominantly in mitochondria"
FT                   /db_xref="GOA:P25374"
FT                   /db_xref="InterPro:IPR000192"
FT                   /db_xref="InterPro:IPR010240"
FT                   /db_xref="InterPro:IPR015421"
FT                   /db_xref="InterPro:IPR015422"
FT                   /db_xref="InterPro:IPR015424"
FT                   /db_xref="InterPro:IPR020578"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25374"
FT                   /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
FT                   [PMID:19720832]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005739
FT                   mitochondrion
FT                   [PMID:10406803|PMID:19720832|PMID:14576278|PMID:16823961|P
FT                   MID:24769239]"
FT                   /experiment="EXISTENCE:direct assay:GO:0016226 iron-sulfur
FT                   cluster assembly [PMID:15220327]"
FT                   /experiment="EXISTENCE:direct assay:GO:0031071 cysteine
FT                   desulfurase activity [PMID:12065597|PMID:15220327]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0002098 tRNA
FT                   wobble uridine modification [PMID:18755837]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0005634 nucleus
FT                   [PMID:11110795]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006879 cellular
FT                   iron ion homeostasis [PMID:10551871]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0016226
FT                   iron-sulfur cluster assembly [PMID:12970193]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0034227 tRNA
FT                   thio-modification [PMID:14722066|PMID:15220327]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0070903
FT                   mitochondrial tRNA thio-modification [PMID:14722066]"
FT                   /experiment="EXISTENCE:physical interaction:GO:1990221
FT                   L-cysteine desulfurase complex [PMID:24045011]"
FT                   /protein_id="DAA07466.1"
FT                   /translation="MLKSTATRSITRLSQVYNVPAATYRACLVSRRFYSPPAAGVKLDD
FT                   NFSLETHTDIQAAAKAQASARASASGTTPDAVVASGSTAMSHAYQENTGFGTRPIYLDM
FT                   QATTPTDPRVLDTMLKFYTGLYGNPHSNTHSYGWETNTAVENARAHVAKMINADPKEII
FT                   FTSGATESNNMVLKGVPRFYKKTKKHIITTRTEHKCVLEAARAMMKEGFEVTFLNVDDQ
FT                   GLIDLKELEDAIRPDTCLVSVMAVNNEIGVIQPIKEIGAICRKNKIYFHTDAAQAYGKI
FT                   HIDVNEMNIDLLSISSHKIYGPKGIGAIYVRRRPRVRLEPLLSGGGQERGLRSGTLAPP
FT                   LVAGFGEAARLMKKEFDNDQAHIKRLSDKLVKGLLSAEHTTLNGSPDHRYPGCVNVSFA
FT                   YVEGESLLMALRDIALSSGSACTSASLEPSYVLHALGKDDALAHSSIRFGIGRFSTEEE
FT                   VDYVVKAVSDRVKFLRELSPLWEMVQEGIDLNSIKWSGH"
FT   gene            complement(94621..95763)
FT                   /gene="DCC1"
FT                   /locus_tag="YCL016C"
FT   mRNA            complement(94621..95763)
FT                   /gene="DCC1"
FT                   /locus_tag="YCL016C"
FT                   /product="Dcc1p"
FT   CDS_pept        complement(94621..95763)
FT                   /codon_start=1
FT                   /gene="DCC1"
FT                   /locus_tag="YCL016C"
FT                   /product="Dcc1p"
FT                   /note="Subunit of a complex with Ctf8p and Ctf18p; shares
FT                   some components with Replication Factor C; required for
FT                   sister chromatid cohesion and telomere length maintenance"
FT                   /db_xref="GOA:P25559"
FT                   /db_xref="InterPro:IPR019128"
FT                   /db_xref="PDB:5MSM"
FT                   /db_xref="PDB:5MSN"
FT                   /db_xref="PDB:5OKC"
FT                   /db_xref="PDB:5OKI"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25559"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0007064
FT                   mitotic sister chromatid cohesion [PMID:17483413]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006974 cellular
FT                   response to DNA damage stimulus [PMID:12482937]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0007064 mitotic
FT                   sister chromatid cohesion [PMID:11389843]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0035753
FT                   maintenance of DNA trinucleotide repeats [PMID:21347277]"
FT                   /experiment="EXISTENCE:physical interaction:GO:0031390
FT                   Ctf18 RFC-like complex [PMID:11389843]"
FT                   /protein_id="DAA07467.1"
FT                   /translation="MSINLHSAPEYDPSYKLIQLTPELLDIIQDPVQNHQLRFKSLDKD
FT                   KSEVVLCSHDKTWVLKQRKHSNTVLLMREFVPEQPITFDETLLFGLSKPYMDVVGFAKT
FT                   ESEFETRETHGELNLNSVPIYNGELDFSDKIMKRSSTKVIGTLEELLENSPCSALEGIS
FT                   KWHKIGGSVKDGVLCILSQDFLFKALHVLLMSAMAESLDLQHLNVEDTHHAVGKDIEDE
FT                   FNPYTREIIETVLNKFAVQEQEAENNTWRLRIPFIAQWYGIQALRKYVSGISMPIDEFL
FT                   IKWKSLFPPFFPCDIDIDMLRGYHFKPTDKTVQYIAKSTLPMDPKERFKVLFRLQSQWD
FT                   LEDIKPLIEELNSRGMKIDSFIMKYARRKRLGKKTVVTSR"
FT   gene            96281..101191
FT                   /gene="BUD3"
FT                   /gene_synonym="YCL012W"
FT                   /locus_tag="YCL014W"
FT   mRNA            96281..101191
FT                   /gene="BUD3"
FT                   /gene_synonym="YCL012W"
FT                   /locus_tag="YCL014W"
FT                   /product="Bud3p"
FT   CDS_pept        96281..101191
FT                   /codon_start=1
FT                   /gene="BUD3"
FT                   /gene_synonym="YCL012W"
FT                   /locus_tag="YCL014W"
FT                   /product="Bud3p"
FT                   /note="Guanine nucleotide exchange factor (GEF) for Cdc42p;
FT                   activates Cdc42p in early G1, accounting for the first
FT                   stage of biphasic activation, with Cdc24p accounting for
FT                   the second stage in late G1; involved in the
FT                   Cdc42p-mediated assembly of the axial landmark that
FT                   dictates the site for the next round of budding, resulting
FT                   in the axial budding pattern observed in haploids;
FT                   localizes with septins to the bud neck contractile ring in
FT                   mitosis"
FT                   /db_xref="GOA:P25558"
FT                   /db_xref="InterPro:IPR000219"
FT                   /db_xref="InterPro:IPR021895"
FT                   /db_xref="InterPro:IPR035899"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25558"
FT                   /experiment="EXISTENCE:direct assay:GO:0000142 cellular bud
FT                   neck contractile ring [PMID:7730410]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005089 Rho
FT                   guanyl-nucleotide exchange factor activity [PMID:25002677]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005935 cellular bud
FT                   neck [PMID:12972503]"
FT                   /experiment="EXISTENCE:direct assay:GO:0043547 positive
FT                   regulation of GTPase activity [PMID:25002677]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0043547
FT                   positive regulation of GTPase activity [PMID:25002677]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000755 cytogamy
FT                   [PMID:9744878]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0005089 Rho
FT                   guanyl-nucleotide exchange factor activity [PMID:25002677]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0007120 axial
FT                   cellular bud site selection [PMID:2065354]"
FT                   /protein_id="DAA07468.1"
FT                   /translation="MEKDLSSLYSEKKDKENDETLFNIKLSKSVVETTPLNGHSLFDDD
FT                   KSLSDWTDNVFTQSVFYHGSDDLIWGKFFVCVYKSPNSNKLNAIIFDKLGTSCFESVDI
FT                   SSNSQYYPAIENLSPSDQESNVKKCIAVILLQRYPLLSPSDLSQILSNKSENCDYDPPY
FT                   AGDLASSCQLITAVPPEDLGKRFFTSGLLQNRFVSSTLLDVIYENNESTIELNNRLVFH
FT                   LGEQLEQLFNPVTEYSPEQTEYGYKAPEDELPTESDDDLVKAICNELLQLQTNFTFNLV
FT                   EFLQKFLIALRVRVLNEEINGLSTTKLNRLFPPTIDEVTRINCIFLDSLKTAIPYGSLE
FT                   VLKACSITIPYFYKAYTRHEAATKNFSKDIKLFIRHFSNVIPEREVYTEMKIESIIKGP
FT                   QEKLLKLKLIIERLWKSKKWRPKNQEMAKKCYNNIIDVIDSFGKLDSPLHSYSTRVFTP
FT                   SGKILTELAKCWPVELQYKWLKRRVVGVYDVVDLNDENKRNLLVIFSDYVVFINILEAE
FT                   SYYTSDGSNRPLISDILMNSLINEVPLPSKIPKLKVERHCYIDEVLVSILDKSTLRFDR
FT                   LKGKDSFSMVCKLSSAFISSSSVADLITKARILEKDTAFHLFKASRSHFTLYSTAHELC
FT                   AYDSEKIKSKFALFLNIPPSKEILEVNNLHLAFFARFCSNDGRDNIVILDVLTKHDDKH
FT                   IEVTSDNIVFTIINQLAIEIPICFSSLNSSMAKDLLCVNENLIKNLEHQLEEVKHPSTD
FT                   EHRAVNSKLSGASDFDATHEKKRSYGTITTFRSYTSDLKDSPSGDNSNVTKETKEILPV
FT                   KPTKKSSKKPREIQKKTKTNASKAEHIEKKKPNKGKGFFGVLKNVFGSKSKSKPSPVQR
FT                   VPKKISQRHPKSPVKKPMTSEKKSSPKRAVVSSPKIKKKSTSFSTKESQTAKSSLRAVE
FT                   FKSDDLIGKPPDVGNGAHPQENTRISSVVRDTKYVSYNPSQPVTENTSNEKNVEPKADQ
FT                   STKQDNISNFADVEVSASSYPEKLDAETDDQIIGKATNSSSVHGNKELPDLAEVTTANR
FT                   VSTTSAGDQRIDTQSEFLRAADVENLSDDDEHRQNESRVFNDDLFGDFIPKHYRNKQEN
FT                   INSSSNLFPEGKVPQEKGVSNENTNISLKTNEDASTLTQKLSPQASKVLTENSNELKDT
FT                   NNEGKDAKDIKLGDDYSDKETAKEITKPKNFVEGITERKEIFPTIPRLAPPASKINFQR
FT                   SPSYIELFQGMRVVLDKHDAHYNWKRLASQVSLSEGLKVNTEEDAAIINKSQDDAKAER
FT                   MTQISEVIEYEMQQPIPTYLPKAHLDDSGIEKSDDKFFEIEEELKEELKGSKTGNEDVG
FT                   NNNPSNSIPKIEKPPAFKVIRTSPVRIIGRTFEDTRKYENGSPSDISFTYDTHNNDEPD
FT                   KRLMELKFPSQDEIPDDRFYTPAEEPTAEFPVEELPNTPRSINVTTSNNKSTDDKLSSG
FT                   NIDQKPTELLDDLEFSSFNIAFGNTSMSTDNMKISSDLSSNKTVLGNAQKVQESPSGPL
FT                   IYVLPQSSTKHEKEGFLRKKQKDEPIWVSPSKIDFADLSRRTKALTPERNTVPLKNNDS
FT                   RKYKYTGEGSIGNMTNMLLTKDASYAYLKDFVALSDDEDEDGKQNCAVGGPEKLKFY"
FT   gene            complement(101317..101788)
FT                   /gene_synonym="YCL011C-A"
FT                   /locus_tag="YCL012C"
FT   mRNA            complement(join(101317..101633,101701..101788))
FT                   /gene_synonym="YCL011C-A"
FT                   /locus_tag="YCL012C"
FT                   /product="hypothetical protein"
FT   CDS_pept        complement(join(101317..101633,101701..101788))
FT                   /codon_start=1
FT                   /gene_synonym="YCL011C-A"
FT                   /locus_tag="YCL012C"
FT                   /product="hypothetical protein"
FT                   /note="hypothetical protein; SWAT-GFP and mCherry fusion
FT                   proteins localize to the endoplasmic reticulum and vacuole
FT                   respectively; orthologs are present in S. bayanus, S.
FT                   paradoxus and Ashbya gossypii; YCL012C is not an essential
FT                   gene"
FT                   /db_xref="GOA:Q8J0M4"
FT                   /db_xref="InterPro:IPR018559"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q8J0M4"
FT                   /protein_id="DAA07469.1"
FT                   /translation="MKSLFYLKLLLWVVLLSLCLLMAHRKTKVADKFRALRSRIQLRFN
FT                   RHIRLNDSFADDLENGLHSRNFDIISENSNDVRGGLDDVSKNEIKQIMENDNVDFDKAR
FT                   LLYMERKFGQNGIAPDGTPIDPKAFTFDSR"
FT   gene            complement(102075..103358)
FT                   /gene="GBP2"
FT                   /gene_synonym="RLF6"
FT                   /locus_tag="YCL011C"
FT   mRNA            complement(102075..103358)
FT                   /gene="GBP2"
FT                   /gene_synonym="RLF6"
FT                   /locus_tag="YCL011C"
FT                   /product="single-stranded telomeric
FT                   DNA-binding/mRNA-binding protein"
FT   CDS_pept        complement(102075..103358)
FT                   /codon_start=1
FT                   /gene="GBP2"
FT                   /gene_synonym="RLF6"
FT                   /locus_tag="YCL011C"
FT                   /product="single-stranded telomeric
FT                   DNA-binding/mRNA-binding protein"
FT                   /note="Poly(A+) RNA-binding protein; key surveillance
FT                   factor for the selective export of spliced mRNAs from the
FT                   nucleus to the cytoplasm; preference for intron-containing
FT                   genes; similar to Npl3p; also binds single-stranded
FT                   telomeric repeat sequence in vitro; relocalizes to the
FT                   cytosol in response to hypoxia; GBP2 has a paralog, HRB1,
FT                   that arose from the whole genome duplication"
FT                   /db_xref="GOA:P25555"
FT                   /db_xref="InterPro:IPR000504"
FT                   /db_xref="InterPro:IPR012677"
FT                   /db_xref="InterPro:IPR035979"
FT                   /db_xref="PDB:2MZQ"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25555"
FT                   /experiment="EXISTENCE:direct assay:GO:0000723 telomere
FT                   maintenance [PMID:12519786]"
FT                   /experiment="EXISTENCE:direct assay:GO:0003682 chromatin
FT                   binding [PMID:14769921]"
FT                   /experiment="EXISTENCE:direct assay:GO:0003729 mRNA binding
FT                   [PMID:12634846|PMID:23222640|PMID:14769921]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
FT                   [PMID:12634846|PMID:22932476]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005829 cytosol
FT                   [PMID:22932476]"
FT                   /experiment="EXISTENCE:direct assay:GO:0010494 cytoplasmic
FT                   stress granule [PMID:18981231|PMID:26777405]"
FT                   /experiment="EXISTENCE:direct assay:GO:0043047
FT                   single-stranded telomeric DNA binding
FT                   [PMID:7777547|PMID:7800479]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0000723
FT                   telomere maintenance [PMID:12519786]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000723 telomere
FT                   maintenance [PMID:12519786]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0016973 poly(A)+
FT                   mRNA export from nucleus [PMID:12634846]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0043047
FT                   single-stranded telomeric DNA binding [PMID:7777547]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0071028 nuclear
FT                   mRNA surveillance [PMID:24452287]"
FT                   /protein_id="DAA07470.1"
FT                   /translation="MERELGMYGNDRSRSRSPVRRRLSDDRDRYDDYNDSSSNNGNGSR
FT                   RQRRDRGSRFNDRYDQSYGGSRYHDDRNWPPRRGGRGRGGSRSFRGGRGGGRGRTLGPI
FT                   VERDLERQFDATKRNFENSIFVRNLTFDCTPEDLKELFGTVGEVVEADIITSKGHHRGM
FT                   GTVEFTKNESVQDAISKFDGALFMDRKLMVRQDNPPPEAAKEFSKKATREEIDNGFEVF
FT                   IINLPYSMNWQSLKDMFKECGHVLRADVELDFNGFSRGFGSVIYPTEDEMIRAIDTFNG
FT                   MEVEGRVLEVREGRFNKRKNNDRYNQRREDLEDTRGTEPGLAQDAAVHIDETAAKFTEG
FT                   VNPGGDRNCFIYCSNLPFSTARSDLFDLFGPIGKINNAELKPQENGQPTGVAVVEYENL
FT                   VDADFCIQKLNNYNYGGCSLQISYARRD"
FT   gene            complement(103571..104350)
FT                   /gene="SGF29"
FT                   /locus_tag="YCL010C"
FT   mRNA            complement(103571..104350)
FT                   /gene="SGF29"
FT                   /locus_tag="YCL010C"
FT                   /product="Sgf29p"
FT   CDS_pept        complement(103571..104350)
FT                   /codon_start=1
FT                   /gene="SGF29"
FT                   /locus_tag="YCL010C"
FT                   /product="Sgf29p"
FT                   /note="Component of the HAT/Core module of the SAGA, SLIK,
FT                   and ADA complexes; HAT/Core module also contains Gcn5p,
FT                   Ngg1p, and Ada2p; binds methylated histone H3K4; involved
FT                   in transcriptional regulation through SAGA and TBP
FT                   recruitment to target promoters and H3 acetylation"
FT                   /db_xref="GOA:P25554"
FT                   /db_xref="InterPro:IPR010750"
FT                   /db_xref="InterPro:IPR037802"
FT                   /db_xref="PDB:3MP1"
FT                   /db_xref="PDB:3MP6"
FT                   /db_xref="PDB:3MP8"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25554"
FT                   /experiment="EXISTENCE:direct assay:GO:0000124 SAGA complex
FT                   [PMID:12052880]"
FT                   /experiment="EXISTENCE:direct assay:GO:0035064 methylated
FT                   histone binding [PMID:21685874]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0001135 RNA
FT                   polymerase II transcription regulator recruiting activity
FT                   [PMID:21685874]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0005671
FT                   Ada2/Gcn5/Ada3 transcription activator complex
FT                   [PMID:21734642]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0034613 cellular
FT                   protein localization [PMID:22224423]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0034629 cellular
FT                   protein-containing complex localization [PMID:21685874]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0043970 histone
FT                   H3-K9 acetylation [PMID:21685874]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0043971 histone
FT                   H3-K18 acetylation [PMID:21685874]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0044154 histone
FT                   H3-K14 acetylation [PMID:21685874]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0045944 positive
FT                   regulation of transcription by RNA polymerase II
FT                   [PMID:21685874]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0070868
FT                   heterochromatin organization involved in chromatin
FT                   silencing [PMID:24307402]"
FT                   /experiment="EXISTENCE:physical interaction:GO:0005671
FT                   Ada2/Gcn5/Ada3 transcription activator complex
FT                   [PMID:21734642]"
FT                   /protein_id="DAA07471.1"
FT                   /translation="MDGYWDVVVSSLQDIYNANEVIPFDDELQTKKLNFLNMSKDQLQL
FT                   HLNTFQEHMENVNRVHRILDNVRSNLSLMLNQSREEKSEENTEDAEEGEGTRMALSQGK
FT                   KAVGKVGRSYWTSEYNPNAPILVGSEVAYKPRRGSADGEWIQCEVLKVVADGTRFEVRD
FT                   PEPDELGNSGKVYKCNRKELLLIPPGFPTKNYPPGTKVLARYPETTTFYPAIVIGTKRD
FT                   GTCRLRFDGEEEVDKETEVTRRLVLPSPTALANLARK"
FT   gene            complement(104619..105548)
FT                   /gene="ILV6"
FT                   /locus_tag="YCL009C"
FT   mRNA            complement(104619..105548)
FT                   /gene="ILV6"
FT                   /locus_tag="YCL009C"
FT                   /product="acetolactate synthase regulatory subunit"
FT   CDS_pept        complement(104619..105548)
FT                   /codon_start=1
FT                   /gene="ILV6"
FT                   /locus_tag="YCL009C"
FT                   /product="acetolactate synthase regulatory subunit"
FT                   /note="Regulatory subunit of acetolactate synthase;
FT                   acetolactate synthase catalyzes the first step of
FT                   branched-chain amino acid biosynthesis; enhances activity
FT                   of the Ilv2p catalytic subunit, localizes to mitochondria"
FT                   /db_xref="GOA:P25605"
FT                   /db_xref="InterPro:IPR002912"
FT                   /db_xref="InterPro:IPR004789"
FT                   /db_xref="InterPro:IPR019455"
FT                   /db_xref="InterPro:IPR027271"
FT                   /db_xref="InterPro:IPR039557"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25605"
FT                   /experiment="EXISTENCE:direct assay:GO:0003984 acetolactate
FT                   synthase activity [PMID:16390333|PMID:8972574]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005739
FT                   mitochondrion [PMID:14576278|PMID:16823961|PMID:24769239]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005948 acetolactate
FT                   synthase complex [PMID:10213630]"
FT                   /experiment="EXISTENCE:direct assay:GO:0009082
FT                   branched-chain amino acid biosynthetic process
FT                   [PMID:8972574]"
FT                   /experiment="EXISTENCE:direct assay:GO:0030234 enzyme
FT                   regulator activity [PMID:8972574]"
FT                   /experiment="EXISTENCE:direct assay:GO:0042645
FT                   mitochondrial nucleoid [PMID:15692048]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0003984
FT                   acetolactate synthase activity [PMID:16390333]"
FT                   /protein_id="DAA07472.1"
FT                   /translation="MLRSLLQSGHRRVVASSCATMVRCSSSSTSALAYKQMHRHATRPP
FT                   LPTLDTPSWNANSAVSSIIYETPAPSRQPRKQHVLNCLVQNEPGVLSRVSGTLAARGFN
FT                   IDSLVVCNTEVKDLSRMTIVLQGQDGVVEQARRQIEDLVPVYAVLDYTNSEIIKRELVM
FT                   ARISLLGTEYFEDLLLHHHTSTNAGAADSQELVAEIREKQFHPANLPASEVLRLKHEHL
FT                   NDITNLTNNFGGRVVDISETSCIVELSAKPTRISAFLKLVEPFGVLECARSGMMALPRT
FT                   PLKTSTEEAADEDEKISEIVDISQLPPG"
FT   gene            complement(105696..106853)
FT                   /gene="STP22"
FT                   /gene_synonym="AGS1"
FT                   /gene_synonym="VPL15"
FT                   /gene_synonym="VPS23"
FT                   /locus_tag="YCL008C"
FT   mRNA            complement(105696..106853)
FT                   /gene="STP22"
FT                   /gene_synonym="AGS1"
FT                   /gene_synonym="VPL15"
FT                   /gene_synonym="VPS23"
FT                   /locus_tag="YCL008C"
FT                   /product="ubiquitin-binding ESCRT-I subunit protein STP22"
FT   CDS_pept        complement(105696..106853)
FT                   /codon_start=1
FT                   /gene="STP22"
FT                   /gene_synonym="VPL15"
FT                   /gene_synonym="VPS23"
FT                   /gene_synonym="AGS1"
FT                   /locus_tag="YCL008C"
FT                   /product="ubiquitin-binding ESCRT-I subunit protein STP22"
FT                   /note="Component of the ESCRT-I complex; ESCRT-I is
FT                   involved in ubiquitin-dependent sorting of proteins into
FT                   the endosome; prevents polyubiquitination of the
FT                   arrestin-related protein Rim8p, thereby directing its
FT                   monoubiquitination by Rsp5p; homologous to the mouse and
FT                   human Tsg101 tumor susceptibility gene; mutants exhibit a
FT                   Class E Vps phenotype"
FT                   /db_xref="GOA:P25604"
FT                   /db_xref="InterPro:IPR000608"
FT                   /db_xref="InterPro:IPR008883"
FT                   /db_xref="InterPro:IPR016135"
FT                   /db_xref="InterPro:IPR017916"
FT                   /db_xref="InterPro:IPR037202"
FT                   /db_xref="PDB:1UZX"
FT                   /db_xref="PDB:2CAZ"
FT                   /db_xref="PDB:2F66"
FT                   /db_xref="PDB:2F6M"
FT                   /db_xref="PDB:2P22"
FT                   /db_xref="PDB:3R3Q"
FT                   /db_xref="PDB:3R42"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25604"
FT                   /experiment="EXISTENCE:curator inference:GO:0043162
FT                   ubiquitin-dependent protein catabolic process via the
FT                   multivesicular body sorting pathway [PMID:15086794]"
FT                   /experiment="EXISTENCE:direct assay:GO:0000813 ESCRT I
FT                   complex [PMID:15044434]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005768 endosome
FT                   [PMID:11511343]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005829 cytosol
FT                   [PMID:26928762]"
FT                   /experiment="EXISTENCE:direct assay:GO:0009898 cytoplasmic
FT                   side of plasma membrane [PMID:20028738]"
FT                   /experiment="EXISTENCE:direct assay:GO:0043130 ubiquitin
FT                   binding [PMID:19380877]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006612 protein
FT                   targeting to membrane [PMID:11511343]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006623 protein
FT                   targeting to vacuole [PMID:11511343]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0045324 late
FT                   endosome to vacuole transport [PMID:17145965]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:1902915 negative
FT                   regulation of protein polyubiquitination [PMID:23645667]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:1904669 ATP
FT                   export [PMID:26585826]"
FT                   /experiment="EXISTENCE:physical interaction:GO:0000813
FT                   ESCRT I complex [PMID:16615894]"
FT                   /protein_id="DAA07473.1"
FT                   /translation="MSANGKISVPEAVVNWLFKVIQPIYNDGRTTFHDSLALLDNFHSL
FT                   RPRTRVFTHSDGTPQLLLSIYGTISTGEDGSSPHSIPVIMWVPSMYPVKPPFISINLEN
FT                   FDMNTISSSLPIQEYIDSNGWIALPILHCWDPAAMNLIMVVQELMSLLHEPPQDQAPSL
FT                   PPKPNTQLQQEQNTPPLPPKPKSPHLKPPLPPPPPPQPASNALDLMDMDNTDISPTNHH
FT                   EMLQNLQTVVNELYREDVDYVADKILTRQTVMQESIARFHEIIAIDKNHLRAVEQAIEQ
FT                   TMHSLNAQIDVLTANRAKVQQFSSTSHVDDEDVNSIAVAKTDGLNQLYNLVAQDYALTD
FT                   TIECLSRMLHRGTIPLDTFVKQGRELARQQFLVRWHIQRITSPLS"
FT   gene            107023..107417
FT                   /gene="VMA9"
FT                   /gene_synonym="CWH36"
FT                   /gene_synonym="LDB10"
FT                   /locus_tag="YCL005W-A"
FT   mRNA            join(107023..107033,107111..107191,107288..107417)
FT                   /gene="VMA9"
FT                   /gene_synonym="CWH36"
FT                   /gene_synonym="LDB10"
FT                   /locus_tag="YCL005W-A"
FT                   /product="H(+)-transporting V0 sector ATPase subunit e"
FT   CDS_pept        join(107023..107033,107111..107191,107288..107417)
FT                   /codon_start=1
FT                   /gene="VMA9"
FT                   /gene_synonym="CWH36"
FT                   /gene_synonym="LDB10"
FT                   /locus_tag="YCL005W-A"
FT                   /product="H(+)-transporting V0 sector ATPase subunit e"
FT                   /note="Vacuolar H+ ATPase subunit e of the V-ATPase V0
FT                   subcomplex; essential for vacuolar acidification; interacts
FT                   with the V-ATPase assembly factor Vma21p in the ER;
FT                   involved in V0 biogenesis"
FT                   /db_xref="EnsemblGenomes-Gn:YCL005W-A"
FT                   /db_xref="EnsemblGenomes-Tr:YCL005W-A"
FT                   /db_xref="GOA:Q3E7B6"
FT                   /db_xref="InterPro:IPR008389"
FT                   /db_xref="PDB:5TJ5"
FT                   /db_xref="PDB:5VOX"
FT                   /db_xref="PDB:5VOY"
FT                   /db_xref="PDB:5VOZ"
FT                   /db_xref="PDB:6C6L"
FT                   /db_xref="PDB:6O7T"
FT                   /db_xref="PDB:6O7U"
FT                   /db_xref="PDB:6O7V"
FT                   /db_xref="PDB:6O7W"
FT                   /db_xref="PDB:6O7X"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q3E7B6"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000032 cell
FT                   wall mannoprotein biosynthetic process [PMID:14734024]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000220 vacuolar
FT                   proton-transporting V-type ATPase, V0 domain
FT                   [PMID:14970230]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000329
FT                   fungal-type vacuole membrane [PMID:14970230]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0007035 vacuolar
FT                   acidification [PMID:14970230]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0034622 cellular
FT                   protein-containing complex assembly [PMID:16569636]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0042625
FT                   ATPase-coupled ion transmembrane transporter activity
FT                   [PMID:14970230]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0055085
FT                   transmembrane transport [PMID:14970230]"
FT                   /experiment="EXISTENCE:physical interaction:GO:0034622
FT                   cellular protein-containing complex assembly
FT                   [PMID:16569636]"
FT                   /protein_id="DAA07474.1"
FT                   /translation="MSSFYTVVGVFIVVSAMSVLFWIMAPKNNQAVWRSTVILTLAMMF
FT                   LMWAITFLCQLHPLVAPRRSDLRPEFAE"
FT   gene            complement(107504..107712)
FT                   /locus_tag="snR43"
FT   ncRNA           complement(107504..107712)
FT                   /locus_tag="snR43"
FT                   /product="SNR43"
FT                   /note="snoRNA gene; H/ACA box small nucleolar RNA (snoRNA);
FT                   guides pseudouridylation of large subunit (LSU) rRNA at
FT                   position U966 and of 5.8S rRNA at position 73"
FT                   /experiment="EXISTENCE:curator inference:GO:0005730
FT                   nucleolus [PMID:15923376]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0030559 rRNA
FT                   pseudouridylation guide activity
FT                   [PMID:15923376|PMID:18332121]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0031118 rRNA
FT                   pseudouridine synthesis [PMID:15923376|PMID:18332121]"
FT                   /experiment="EXISTENCE:physical interaction:GO:0031429 box
FT                   H/ACA snoRNP complex [PMID:15923376]"
FT                   /ncRNA_class="other"
FT   gene            108021..108791
FT                   /gene="LDB16"
FT                   /locus_tag="YCL005W"
FT   mRNA            108021..108791
FT                   /gene="LDB16"
FT                   /locus_tag="YCL005W"
FT                   /product="Ldb16p"
FT   CDS_pept        108021..108791
FT                   /codon_start=1
FT                   /gene="LDB16"
FT                   /locus_tag="YCL005W"
FT                   /product="Ldb16p"
FT                   /note="Protein involved in lipid droplet (LD) assembly;
FT                   forms a complex with Sei1p at ER-LD contact sites,
FT                   stabilizing contact sites; ensures that LDs bud from the ER
FT                   towards the cytosolic side of the membrane; null mutants
FT                   have decreased net negative cell surface charge and
FT                   localized accumulation of phosphatidic acid (PA) marker
FT                   proteins; GFP-fusion protein expression is induced in
FT                   response to MMS; null mutant can be complemented by the
FT                   human seipin, BSCL2"
FT                   /db_xref="GOA:P25587"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25587"
FT                   /experiment="EXISTENCE:direct assay:GO:0005739
FT                   mitochondrion [PMID:14576278|PMID:16823961]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005811 lipid
FT                   droplet [PMID:14562095]"
FT                   /experiment="EXISTENCE:direct assay:GO:0030176 integral
FT                   component of endoplasmic reticulum membrane
FT                   [PMID:24434579]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0034389 lipid
FT                   droplet organization [PMID:26572621]"
FT                   /protein_id="DAA07475.1"
FT                   /translation="MFVVDWSVQLCMGVISPLFRALVQLPLSIFVWNGFQLVALPINIP
FT                   LRLFLGTSLSRLVAQTSTLDFYVVLTLFQYFAVLCAFGSIIGLIFGFILGVFHSICGVP
FT                   SVYISLEWKRWFAPIRTVLERASTSIVNIMRGQTIAPIPMPKPNPTHISKPNMKKFHDE
FT                   PGADDMTITHDVNCYITPCQTPTNEKIQHYNNDSFNTTTTDDEPTDIWDRSDTYQNSFV
FT                   TNETLMSLSNRAKLRRNASDADIVNIKILRRNSR"
FT   rep_origin      108727..109060
FT                   /note="ARS307; Autonomously Replicating Sequence on
FT                   Chromosome III"
FT   gene            109105..110670
FT                   /gene="PGS1"
FT                   /gene_synonym="PEL1"
FT                   /gene_synonym="YCL003W"
FT                   /locus_tag="YCL004W"
FT   mRNA            109105..110670
FT                   /gene="PGS1"
FT                   /gene_synonym="PEL1"
FT                   /gene_synonym="YCL003W"
FT                   /locus_tag="YCL004W"
FT                   /product="CDP-diacylglycerol--glycerol-3-phosphate
FT                   3-phosphatidyltransferase"
FT   CDS_pept        109105..110670
FT                   /codon_start=1
FT                   /gene="PGS1"
FT                   /gene_synonym="PEL1"
FT                   /gene_synonym="YCL003W"
FT                   /locus_tag="YCL004W"
FT                   /product="CDP-diacylglycerol--glycerol-3-phosphate
FT                   3-phosphatidyltransferase"
FT                   /EC_number="2.7.8.5"
FT                   /note="Phosphatidylglycerolphosphate synthase; catalyzes
FT                   the synthesis of phosphatidylglycerolphosphate from
FT                   CDP-diacylglycerol and sn-glycerol 3-phosphate in the first
FT                   committed and rate-limiting step of cardiolipin
FT                   biosynthesis"
FT                   /db_xref="GOA:P25578"
FT                   /db_xref="InterPro:IPR001736"
FT                   /db_xref="InterPro:IPR016270"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25578"
FT                   /experiment="EXISTENCE:direct assay:GO:0005739
FT                   mitochondrion [PMID:9799363]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0008444
FT                   CDP-diacylglycerol-glycerol-3-phosphate
FT                   3-phosphatidyltransferase activity [PMID:9545322]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0032049
FT                   cardiolipin biosynthetic process [PMID:9545322]"
FT                   /protein_id="DAA07476.1"
FT                   /translation="MTTRLLQLTRPHYRLLSLPLQKPFNIKRQMSAANPSPFGNYLNTI
FT                   TKSLQQNLQTCFHFQAKEIDIIESPSQFYDLLKTKILNSQNRIFIASLYLGKSETELVD
FT                   CISQALTKNPKLKVSFLLDGLRGTRELPSACSATLLSSLVAKYGSERVDCRLYKTPAYH
FT                   GWKKVLVPKRFNEGLGLQHMKIYGFDNEVILSGANLSNDYFTNRQDRYYLFKSRNFSNY
FT                   YFKLHQLISSFSYQIIKPMVDGSINIIWPDSNPTVEPTKNKRLFLREASQLLDGFLKSS
FT                   KQSLPITAVGQFSTLVYPISQFTPLFPKYNDKSTEKRTILSLLSTITSNAISWTFTAGY
FT                   FNILPDIKAKLLATPVAEANVITASPFANGFYQSKGVSSNLPGAYLYLSKKFLQDVCRY
FT                   RQDHAITLREWQRGVVNKPNGWSYHAKGIWLSARDKNDANNWKPFITVIGSSNYTRRAY
FT                   SLDLESNALIITRDEELRKKMKAELDNLLQYTKPVTLEDFQSDPERHVGTGVKIATSIL
FT                   GKKL"
FT   gene            complement(110808..111675)
FT                   /locus_tag="YCL002C"
FT   mRNA            complement(join(110808..111557,111634..111675))
FT                   /locus_tag="YCL002C"
FT                   /product="hypothetical protein"
FT   CDS_pept        complement(join(110808..111557,111634..111675))
FT                   /codon_start=1
FT                   /locus_tag="YCL002C"
FT                   /product="hypothetical protein"
FT                   /note="hypothetical protein; YCL002C is not an essential
FT                   gene"
FT                   /db_xref="GOA:P25565"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25565"
FT                   /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
FT                   [PMID:26928762]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005829 cytosol
FT                   [PMID:26928762]"
FT                   /protein_id="DAA07477.2"
FT                   /translation="MLVIVLQGLAGFLSIIAILCQKRYNKLHRSIYGLSYDLFLLDFVG
FT                   NGLYLYCALHYCYSSLVREQLSQRFPLFYPLNDARSIPISSFLILKDFCVSCCCMMVLR
FT                   QLYYYRSTKHIYQGISITSIIIISVFLVLGIFTYGCSISNLPLKNSGKFGVFYLEHINY
FT                   LWVMANLLKCFKYVPQMSINWMGCSTVGLSSKFALISFLAESIDLLGRLVIPTNALFYE
FT                   IPFNSTPFWVKLIQFVTLLVILCQVQYVYVGRKPRLPKGKL"
FT   gene            111916..112482
FT                   /gene="RER1"
FT                   /locus_tag="YCL001W"
FT   mRNA            111916..112482
FT                   /gene="RER1"
FT                   /locus_tag="YCL001W"
FT                   /product="protein retrieval receptor"
FT   CDS_pept        111916..112482
FT                   /codon_start=1
FT                   /gene="RER1"
FT                   /locus_tag="YCL001W"
FT                   /product="protein retrieval receptor"
FT                   /note="Protein involved in retention of membrane proteins;
FT                   including Sec12p, in the ER; localized to Golgi; functions
FT                   as a retrieval receptor in returning membrane proteins to
FT                   the ER"
FT                   /db_xref="GOA:P25560"
FT                   /db_xref="InterPro:IPR004932"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25560"
FT                   /experiment="EXISTENCE:direct assay:GO:0000324 fungal-type
FT                   vacuole [PMID:22761830]"
FT                   /experiment="EXISTENCE:direct assay:GO:0006890 retrograde
FT                   vesicle-mediated transport, Golgi to endoplasmic reticulum
FT                   [PMID:11238450]"
FT                   /experiment="EXISTENCE:direct assay:GO:0030134 COPII-coated
FT                   ER to Golgi transport vesicle [PMID:11157978]"
FT                   /experiment="EXISTENCE:direct assay:GO:0030137 COPI-coated
FT                   vesicle [PMID:11238450]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006621 protein
FT                   retention in ER lumen [PMID:8707815]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006890
FT                   retrograde vesicle-mediated transport, Golgi to endoplasmic
FT                   reticulum [PMID:11238450]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0030137
FT                   COPI-coated vesicle [PMID:11238450]"
FT                   /protein_id="DAA07478.1"
FT                   /translation="MDYDSSDTMNGGSSNPLITKMNTMKLLYQHYLDKVTPHAKERWAV
FT                   LGGLLCLFMVRITMAEGWYVICYGLGLFLLNQFLAFLTPKFDMSLQQDEENNELEAGEK
FT                   SEEFRPFIRRLPEFKFWYNSIRATVISLLLSLFSIFDIPVFWPILLMYFILLFFLTMRR
FT                   QIQHMIKYRYIPLDIGKKKYSHSSN"
FT   gene            113080..113541
FT                   /locus_tag="YCL001W-A"
FT   mRNA            113080..113541
FT                   /locus_tag="YCL001W-A"
FT                   /product="hypothetical protein"
FT   CDS_pept        113080..113541
FT                   /codon_start=1
FT                   /locus_tag="YCL001W-A"
FT                   /product="hypothetical protein"
FT                   /note="hypothetical protein; YCL001W-A gene has similarity
FT                   to DOM34 and is present in a region duplicated between
FT                   chromosomes XIV and III"
FT                   /db_xref="GOA:P87012"
FT                   /db_xref="UniProtKB/Swiss-Prot:P87012"
FT                   /protein_id="DAA07479.1"
FT                   /translation="MTFLQFINNNRQEGQGYISEKLFKTKKNEMIRKTVTNLVAVRLKN
FT                   LSHEFDVIENYLRYIASTSEHLFTAIKRHFNKCARKLLKEAIDSKSNSETATVVLQEGF
FT                   SGICLLKASSIILKLKLKFPKKKDRTDISKLCDKKERMTQWLEISILMN"
FT   gene            113770..114024
FT                   /locus_tag="YCL001W-B"
FT   mRNA            113770..114024
FT                   /locus_tag="YCL001W-B"
FT                   /product="hypothetical protein"
FT   CDS_pept        113770..114024
FT                   /codon_start=1
FT                   /locus_tag="YCL001W-B"
FT                   /product="hypothetical protein"
FT                   /note="hypothetical protein; present in a region duplicated
FT                   between chromosomes XIV and III; YCL001W-B has a paralog,
FT                   DOM34, that arose from the whole genome duplication"
FT                   /db_xref="GOA:Q96VH2"
FT                   /db_xref="InterPro:IPR004405"
FT                   /db_xref="InterPro:IPR005142"
FT                   /db_xref="InterPro:IPR029064"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q96VH2"
FT                   /protein_id="DAA07480.1"
FT                   /translation="MDDFLEHLSKDDNKAWYGAEETERAAKLDAIETLLITDSVLKRND
FT                   VKKREKYLDLIENSGNNNGKIFVLSTSKITVSNLTNQQI"
FT   rep_origin      114321..114939
FT                   /note="ARS308; Autonomously Replicating Sequence on
FT                   Chromosome III"
FT   centromere      114385..114501
FT                   /note="CEN3; Chromosome III centromere"
FT   centromere      114385..114394
FT                   /note="CEN3_CDEI of CEN3"
FT   centromere      114395..114476
FT                   /note="CEN3_CDEII of CEN3"
FT   centromere      114477..114501
FT                   /note="CEN3_CDEIII of CEN3"
FT   gene            115685..115999
FT                   /locus_tag="YCR001W"
FT   mRNA            115685..115999
FT                   /locus_tag="YCR001W"
FT                   /product="hypothetical protein"
FT   CDS_pept        115685..115999
FT                   /codon_start=1
FT                   /locus_tag="YCR001W"
FT                   /product="hypothetical protein"
FT                   /note="hypothetical protein; conserved among S. cerevisiae
FT                   strains; YCR001W is not an essential gene"
FT                   /db_xref="GOA:P25347"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25347"
FT                   /protein_id="DAA80268.1"
FT                   /translation="MLYLLKKLKHIDSYGESNLSMFYLKFYCPWKLCPLLPILYGRNKS
FT                   VQNAWSCHKLHRFIDFPTPSANMNFFFFIRVCYGTVSLFISTFLKKISFFIYVNFTVYF
FT                   "
FT   gene            complement(117380..118348)
FT                   /gene="CDC10"
FT                   /locus_tag="YCR002C"
FT   mRNA            complement(117380..118348)
FT                   /gene="CDC10"
FT                   /locus_tag="YCR002C"
FT                   /product="septin CDC10"
FT   CDS_pept        complement(117380..118348)
FT                   /codon_start=1
FT                   /gene="CDC10"
FT                   /locus_tag="YCR002C"
FT                   /product="septin CDC10"
FT                   /note="Component of the septin ring, required for
FT                   cytokinesis; septins are GTP-binding proteins that assemble
FT                   into rod-like hetero-oligomers that can associate to form
FT                   filaments; septin rings at the mother-bud neck act as
FT                   scaffolds for recruiting cell division factors and as
FT                   barriers to prevent diffusion of specific proteins between
FT                   mother and daughter cells; N-terminus interacts with
FT                   phosphatidylinositol-4,5-bisphosphate; protein abundance
FT                   increases under DNA damage stress"
FT                   /db_xref="GOA:P25342"
FT                   /db_xref="InterPro:IPR016491"
FT                   /db_xref="InterPro:IPR027417"
FT                   /db_xref="InterPro:IPR030379"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25342"
FT                   /experiment="EXISTENCE:curator inference:GO:0030011
FT                   maintenance of cell polarity [PMID:10882120]"
FT                   /experiment="EXISTENCE:direct assay:GO:0000144 cellular bud
FT                   neck septin ring [PMID:9884239]"
FT                   /experiment="EXISTENCE:direct assay:GO:0001400 mating
FT                   projection base [PMID:18552279]"
FT                   /experiment="EXISTENCE:direct assay:GO:0003924 GTPase
FT                   activity [PMID:14993234]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005200 structural
FT                   constituent of cytoskeleton
FT                   [PMID:18550837|PMID:22144691|PMID:29321251]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005545
FT                   1-phosphatidylinositol binding [PMID:12665577]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005628 prospore
FT                   membrane [PMID:18826657|PMID:24390141]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005876 spindle
FT                   microtubule [PMID:18826657]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005935 cellular bud
FT                   neck [PMID:26928762]"
FT                   /experiment="EXISTENCE:direct assay:GO:0010314
FT                   phosphatidylinositol-5-phosphate binding [PMID:12665577]"
FT                   /experiment="EXISTENCE:direct assay:GO:0031105 septin
FT                   complex [PMID:18550837]"
FT                   /experiment="EXISTENCE:direct assay:GO:0032160 septin
FT                   filament array [PMID:15282341]"
FT                   /experiment="EXISTENCE:direct assay:GO:0042764
FT                   ascospore-type prospore [PMID:18701287]"
FT                   /experiment="EXISTENCE:direct assay:GO:0043332 mating
FT                   projection tip [PMID:19053807]"
FT                   /experiment="EXISTENCE:direct assay:GO:0043934 sporulation
FT                   [PMID:18701287]"
FT                   /experiment="EXISTENCE:direct assay:GO:0060090 molecular
FT                   adaptor activity [PMID:15901837]"
FT                   /experiment="EXISTENCE:direct assay:GO:0070273
FT                   phosphatidylinositol-4-phosphate binding [PMID:12665577]"
FT                   /experiment="EXISTENCE:direct assay:GO:0072687 meiotic
FT                   spindle [PMID:18826657]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000281 mitotic
FT                   cytokinesis [PMID:4950437]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000921 septin
FT                   ring assembly [PMID:14993234]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0010458 exit
FT                   from mitosis [PMID:12699621]"
FT                   /experiment="EXISTENCE:physical interaction:GO:0031105
FT                   septin complex [PMID:9813094]"
FT                   /protein_id="DAA07481.1"
FT                   /translation="MDPLSSVQPASYVGFDTITNQIEHRLLKKGFQFNIMVVGQSGLGK
FT                   STLINTLFASHLIDSATGDDISALPVTKTTEMKISTHTLVEDRVRLNINVIDTPGFGDF
FT                   IDNSKAWEPIVKYIKEQHSQYLRKELTAQRERFITDTRVHAILYFLQPNGKELSRLDVE
FT                   ALKRLTEIANVIPVIGKSDTLTLDERTEFRELIQNEFEKYNFKIYPYDSEELTDEELEL
FT                   NRSVRSIIPFAVVGSENEIEINGETFRGRKTRWSAINVEDINQCDFVYLREFLIRTHLQ
FT                   DLIETTSYIHYEGFRARQLIALKENANSRSSAHMSSNAIQR"
FT   gene            118620..119171
FT                   /gene="MRPL32"
FT                   /gene_synonym="bL32m"
FT                   /locus_tag="YCR003W"
FT   mRNA            118620..119171
FT                   /gene="MRPL32"
FT                   /gene_synonym="bL32m"
FT                   /locus_tag="YCR003W"
FT                   /product="mitochondrial 54S ribosomal protein YmL32"
FT   CDS_pept        118620..119171
FT                   /codon_start=1
FT                   /gene="MRPL32"
FT                   /gene_synonym="bL32m"
FT                   /locus_tag="YCR003W"
FT                   /product="mitochondrial 54S ribosomal protein YmL32"
FT                   /note="Mitochondrial ribosomal protein of the large
FT                   subunit; protein abundance increases in response to DNA
FT                   replication stress"
FT                   /db_xref="GOA:P25348"
FT                   /db_xref="InterPro:IPR002677"
FT                   /db_xref="InterPro:IPR011332"
FT                   /db_xref="PDB:3J6B"
FT                   /db_xref="PDB:5MRC"
FT                   /db_xref="PDB:5MRE"
FT                   /db_xref="PDB:5MRF"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25348"
FT                   /experiment="EXISTENCE:curator inference:GO:0032543
FT                   mitochondrial translation [PMID:2060626]"
FT                   /experiment="EXISTENCE:direct assay:GO:0003735 structural
FT                   constituent of ribosome [PMID:2060626]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005739
FT                   mitochondrion [PMID:16823961|PMID:24769239]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005762
FT                   mitochondrial large ribosomal subunit [PMID:2060626]"
FT                   /protein_id="DAA07482.1"
FT                   /translation="MNSLIFGKQLAFHKIVPTTAIGWLVPLGNPSLQIPGQKQLGSIHR
FT                   WLREKLQQDHKDTEDKDFFSNNGILLAVPKKKVSHQKKRQKLYGPGKKQLKMIHHLNKC
FT                   PSCGHYKRANTLCMYCVGQISHIWKTHTAKEEIKPRQEEELSELDQRVLYPGRRDTKYT
FT                   KDLKDKDNYLERRVRTLKKD"
FT   gene            complement(119575..120318)
FT                   /gene="YCP4"
FT                   /locus_tag="YCR004C"
FT   mRNA            complement(119575..120318)
FT                   /gene="YCP4"
FT                   /locus_tag="YCR004C"
FT                   /product="flavodoxin-like fold family protein"
FT   CDS_pept        complement(119575..120318)
FT                   /codon_start=1
FT                   /gene="YCP4"
FT                   /locus_tag="YCR004C"
FT                   /product="flavodoxin-like fold family protein"
FT                   /note="hypothetical protein; has sequence and structural
FT                   similarity to flavodoxins; predicted to be palmitoylated;
FT                   the authentic, non-tagged protein is detected in highly
FT                   purified mitochondria in high-throughput studies"
FT                   /db_xref="GOA:P25349"
FT                   /db_xref="InterPro:IPR005025"
FT                   /db_xref="InterPro:IPR008254"
FT                   /db_xref="InterPro:IPR010089"
FT                   /db_xref="InterPro:IPR029039"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25349"
FT                   /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
FT                   [PMID:21442317|PMID:14562095]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005739
FT                   mitochondrion [PMID:14576278|PMID:16823961|PMID:24769239]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005886 plasma
FT                   membrane [PMID:16622836]"
FT                   /experiment="EXISTENCE:direct assay:GO:0045121 membrane
FT                   raft [PMID:19064668]"
FT                   /experiment="EXISTENCE:direct assay:GO:0071944 cell
FT                   periphery [PMID:26928762]"
FT                   /protein_id="DAA07483.1"
FT                   /translation="MVKIAIITYSTYGHIDVLAQAVKKGVEAAGGKADIYRVEETLPDE
FT                   VLTKMNAPQKPEDIPVATEKTLLEYDAFLFGVPTRFGNLPAQWSAFWDKTGGLWAKGSL
FT                   NGKAAGIFVSTSSYGGGQESTVKACLSYLAHHGIIFLPLGYKNSFAELASIEEVHGGSP
FT                   WGAGTLAGPDGSRTASPLELRIAEIQGKTFYETAKKLFPAKEAKPSTEKKTTTSDAAKR
FT                   QTKPAAATTAEKKEDKGLLSCCTVM"
FT   gene            complement(120946..122328)
FT                   /gene="CIT2"
FT                   /locus_tag="YCR005C"
FT   mRNA            complement(120946..122328)
FT                   /gene="CIT2"
FT                   /locus_tag="YCR005C"
FT                   /product="citrate (Si)-synthase CIT2"
FT   CDS_pept        complement(120946..122328)
FT                   /codon_start=1
FT                   /gene="CIT2"
FT                   /locus_tag="YCR005C"
FT                   /product="citrate (Si)-synthase CIT2"
FT                   /EC_number="2.3.3.16"
FT                   /note="Citrate synthase, peroxisomal isozyme involved in
FT                   glyoxylate cycle; catalyzes condensation of acetyl coenzyme
FT                   A and oxaloacetate to form citrate; expression is
FT                   controlled by Rtg1p and Rtg2p transcription factors;
FT                   SCF-Ucc1 regulates level of Cit2p to maintain citrate
FT                   homeostasis; oxaloacetate-dependent positive feedback loop
FT                   inhibits Cit2p ubiquitination; CIT2 has a paralog, CIT1,
FT                   that arose from the whole genome duplication"
FT                   /db_xref="GOA:P08679"
FT                   /db_xref="InterPro:IPR002020"
FT                   /db_xref="InterPro:IPR010109"
FT                   /db_xref="InterPro:IPR016142"
FT                   /db_xref="InterPro:IPR016143"
FT                   /db_xref="InterPro:IPR019810"
FT                   /db_xref="InterPro:IPR036969"
FT                   /db_xref="UniProtKB/Swiss-Prot:P08679"
FT                   /experiment="EXISTENCE:direct assay:GO:0004108 citrate
FT                   (Si)-synthase activity [PMID:2181273]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
FT                   [PMID:25982115]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005739
FT                   mitochondrion [PMID:14576278|PMID:16823961]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005777 peroxisome
FT                   [PMID:16877773|PMID:25982115]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0004108
FT                   citrate (Si)-synthase activity [PMID:2181273]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0006101
FT                   citrate metabolic process [PMID:12913175]"
FT                   /protein_id="DAA07484.1"
FT                   /translation="MTVPYLNSNRNVASYLQSNSSQEKTLKERFSEIYPIHAQDVRQFV
FT                   KEHGKTKISDVLLEQVYGGMRGIPGSVWEGSVLDPEDGIRFRGRTIADIQKDLPKAKGS
FT                   SQPLPEALFWLLLTGEVPTQAQVENLSADLMSRSELPSHVVQLLDNLPKDLHPMAQFSI
FT                   AVTALESESKFAKAYAQGISKQDYWSYTFEDSLDLLGKLPVIAAKIYRNVFKDGKMGEV
FT                   DPNADYAKNLVNLIGSKDEDFVDLMRLYLTIHSDHEGGNVSAHTSHLVGSALSSPYLSL
FT                   ASGLNGLAGPLHGRANQEVLEWLFALKEEVNDDYSKDTIEKYLWDTLNSGRVIPGYGHA
FT                   VLRKTDPRYMAQRKFAMDHFPDYELFKLVSSIYEVAPGVLTEHGKTKNPWPNVDAHSGV
FT                   LLQYYGLKESSFYTVLFGVSRAFGILAQLITDRAIGASIERPKSYSTEKYKELVKNIES
FT                   KL"
FT   gene            complement(122530..123003)
FT                   /locus_tag="YCR006C"
FT   mRNA            complement(122530..123003)
FT                   /locus_tag="YCR006C"
FT                   /product="hypothetical protein"
FT   CDS_pept        complement(122530..123003)
FT                   /codon_start=1
FT                   /locus_tag="YCR006C"
FT                   /product="hypothetical protein"
FT                   /note="hypothetical protein; conserved among S. cerevisiae
FT                   strains; YCR006C is not an essential gene"
FT                   /db_xref="GOA:P25350"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25350"
FT                   /protein_id="DAA80269.1"
FT                   /translation="MFIRVCNRLIYTPTNVLLITVEDGRISVLLWFRYAIPAELCYTRL
FT                   ARILRGKHCADFPQSCCHNISRFGVLNKSVLGSFNQWLGGISKERKLIARTFDAFIRWS
FT                   STRGEEVTTYFFLQKKSVTFSVARRLSGRQQWEAQRKNNNNGKRNYLLSVTFV"
FT   gene            complement(123577..123648)
FT                   /gene="SUF2"
FT                   /locus_tag="tP(AGG)C"
FT   tRNA            complement(123577..123648)
FT                   /gene="SUF2"
FT                   /locus_tag="tP(AGG)C"
FT                   /product="tRNA-Pro"
FT                   /note="tP(AGG)C; Proline tRNA (tRNA-Pro), predicted by
FT                   tRNAscan-SE analysis; can mutate to suppress +1 frameshift
FT                   mutations in proline codons"
FT                   /experiment="EXISTENCE:curator inference:GO:0005829 cytosol
FT                   [PMID:9023104]"
FT                   /experiment="EXISTENCE:curator inference:GO:0006414
FT                   translational elongation [PMID:9023104]"
FT   repeat_region   complement(124134..124465)
FT                   /rpt_type=LONG_TERMINAL_REPEAT
FT                   /note="Ty1 LTR"
FT   gene            complement(126011..126730)
FT                   /locus_tag="YCR007C"
FT   mRNA            complement(126011..126730)
FT                   /locus_tag="YCR007C"
FT                   /product="DUP240 family protein"
FT   CDS_pept        complement(126011..126730)
FT                   /codon_start=1
FT                   /locus_tag="YCR007C"
FT                   /product="DUP240 family protein"
FT                   /note="Putative integral membrane protein; member of DUP240
FT                   gene family; SWAT-GFP and mCherry fusion proteins localize
FT                   to the cell periphery and vacuole; YCR007C is not an
FT                   essential gene"
FT                   /db_xref="GOA:P25354"
FT                   /db_xref="InterPro:IPR001142"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25354"
FT                   /experiment="EXISTENCE:direct assay:GO:0000324 fungal-type
FT                   vacuole [PMID:26928762]"
FT                   /experiment="EXISTENCE:direct assay:GO:0071944 cell
FT                   periphery [PMID:26928762]"
FT                   /protein_id="DAA07485.1"
FT                   /translation="MQPHLDNNSNNDDVKLDTLGEQNVLSSAENITLPEDTFKSYMTYL
FT                   LYEMAHYKPMIFSFLALSVSILIVVIFHNVKACDVVFGFSIFVTSILFLSTLIPFNVYI
FT                   SDEGFRIKLLLEVITHRPAVKGKEWRAITDNMNQYLLDNGLWSTRYYFYSSERCYKFFR
FT                   FLVKEKPPGVNVNSSVKDATSTQIDAPANEASNEVIKCFSFSSDPIFEAYFVKAVEVEK
FT                   QAQQEYWRKQYPDADIP"
FT   gene            127716..127789
FT                   /locus_tag="tN(GUU)C"
FT   tRNA            127716..127789
FT                   /locus_tag="tN(GUU)C"
FT                   /product="tRNA-Asn"
FT                   /note="tN(GUU)C; Asparagine tRNA (tRNA-Asn), predicted by
FT                   tRNAscan-SE analysis"
FT                   /experiment="EXISTENCE:curator inference:GO:0005829 cytosol
FT                   [PMID:9023104]"
FT                   /experiment="EXISTENCE:curator inference:GO:0006414
FT                   translational elongation [PMID:9023104]"
FT   gene            128470..130281
FT                   /gene="SAT4"
FT                   /gene_synonym="HAL4"
FT                   /locus_tag="YCR008W"
FT   mRNA            128470..130281
FT                   /gene="SAT4"
FT                   /gene_synonym="HAL4"
FT                   /locus_tag="YCR008W"
FT                   /product="serine/threonine protein kinase SAT4"
FT   CDS_pept        128470..130281
FT                   /codon_start=1
FT                   /gene="SAT4"
FT                   /gene_synonym="HAL4"
FT                   /locus_tag="YCR008W"
FT                   /product="serine/threonine protein kinase SAT4"
FT                   /EC_number="2.7.11.1"
FT                   /note="Ser/Thr protein kinase involved in salt tolerance;
FT                   funtions in regulation of Trk1p-Trk2p potassium
FT                   transporter; overexpression affects the Fe-S and lipoamide
FT                   containing proteins in the mitochondrion; required for
FT                   lipoylation of Lat1p, Kgd2p and Gcv3p; partially redundant
FT                   with Hal5p; has similarity to Npr1p; localizes to the
FT                   cytoplasm and mitochondrion"
FT                   /db_xref="GOA:P25333"
FT                   /db_xref="InterPro:IPR000719"
FT                   /db_xref="InterPro:IPR008271"
FT                   /db_xref="InterPro:IPR011009"
FT                   /db_xref="InterPro:IPR017441"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25333"
FT                   /experiment="EXISTENCE:direct assay:GO:0004672 protein
FT                   kinase activity [PMID:16319894]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
FT                   [PMID:25117470]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005739
FT                   mitochondrion [PMID:25117470]"
FT                   /experiment="EXISTENCE:direct assay:GO:0006468 protein
FT                   phosphorylation [PMID:16319894]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0000082 G1/S
FT                   transition of mitotic cell cycle [PMID:12518319]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0034613
FT                   cellular protein localization [PMID:21237705]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006470 protein
FT                   dephosphorylation [PMID:21237705]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0009249 protein
FT                   lipoylation [PMID:25117470]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0030003 cellular
FT                   cation homeostasis [PMID:10207057]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:1903329
FT                   regulation of iron-sulfur cluster assembly [PMID:25117470]"
FT                   /protein_id="DAA07486.1"
FT                   /translation="MTGMNDNNAAIPQQTPRKHALSSKVMQLFRSGSRSSRQGKASSNI
FT                   QPPSNINTNVPSASKSAKFGLHTPTTATPRVVSNPSNTAGVSKPGMYMPEYYQSASPSH
FT                   SSSSASLNNHIDINTSKSSSAASLTSSVSALSLSPTSAINISSKSLSPKFSHHSNSNTA
FT                   ITPAPTPTASNINNVNKITNTSAPICGRFLVHKDGTHEHHLKNAKRQEKLSTMIKNMVG
FT                   ASKLRGEAKSAVPDIIMDPKTTLKSNKNPPTLFAGFMKQVVDMDDKYPEGAPTSGALNC
FT                   PERDIYRSDQKDSKNNTHNITTTKKDRQCFAEKYGRCQEVLGKGAFGVVRICQKKNVSS
FT                   QDGNKSEKLYAVKEFKRRTSESAEKYSKRLTSEFCISSSLHHTNIVTTLDLFQDAKGEY
FT                   CEVMEYCAGGDLFTLVVAAGKLEYMEADCFFKQLIRGVVYMHEMGVCHRDLKPENLLLT
FT                   HDGVLKITDFGNSECFKMAWEKNIHLSGGVCGSSPYIAPEEYIKEEFDPRPVDIWACGV
FT                   IYMAMRTGRQLWSSAEKDDPFYMNYLKGRKEKGGYEPIESLKRARCRNVIYSMLDPVPY
FT                   RRINGKQILNSEWGREIKCCHNGRALK"
FT   gene            complement(130745..131542)
FT                   /gene="RVS161"
FT                   /gene_synonym="END6"
FT                   /gene_synonym="FUS7"
FT                   /gene_synonym="SPE161"
FT                   /locus_tag="YCR009C"
FT   mRNA            complement(130745..131542)
FT                   /gene="RVS161"
FT                   /gene_synonym="END6"
FT                   /gene_synonym="FUS7"
FT                   /gene_synonym="SPE161"
FT                   /locus_tag="YCR009C"
FT                   /product="amphiphysin-like protein RVS161"
FT   CDS_pept        complement(130745..131542)
FT                   /codon_start=1
FT                   /gene="RVS161"
FT                   /gene_synonym="END6"
FT                   /gene_synonym="FUS7"
FT                   /gene_synonym="SPE161"
FT                   /locus_tag="YCR009C"
FT                   /product="amphiphysin-like protein RVS161"
FT                   /note="Amphiphysin-like lipid raft protein; N-BAR domain
FT                   protein that interacts with Rvs167p and regulates
FT                   polarization of the actin cytoskeleton, endocytosis, cell
FT                   polarity, cell fusion and viability following starvation or
FT                   osmotic stress"
FT                   /db_xref="GOA:P25343"
FT                   /db_xref="InterPro:IPR004148"
FT                   /db_xref="InterPro:IPR027267"
FT                   /db_xref="InterPro:IPR037429"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25343"
FT                   /experiment="EXISTENCE:direct assay:GO:0005829 cytosol
FT                   [PMID:26928762]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005937 mating
FT                   projection [PMID:9566960]"
FT                   /experiment="EXISTENCE:direct assay:GO:0008289 lipid
FT                   binding [PMID:20610658|PMID:27093085]"
FT                   /experiment="EXISTENCE:direct assay:GO:0030479 actin
FT                   cortical patch [PMID:16239147]"
FT                   /experiment="EXISTENCE:direct assay:GO:0043332 mating
FT                   projection tip [PMID:19053807]"
FT                   /experiment="EXISTENCE:direct assay:GO:0045121 membrane
FT                   raft [PMID:12477802]"
FT                   /experiment="EXISTENCE:direct assay:GO:0060988 lipid tube
FT                   assembly [PMID:20610658]"
FT                   /experiment="EXISTENCE:direct assay:GO:0097320 plasma
FT                   membrane tubulation [PMID:27093085]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000747
FT                   conjugation with cellular fusion [PMID:11096097]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006897
FT                   endocytosis [PMID:8590801]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006970 response
FT                   to osmotic stress [PMID:1776363]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0030036 actin
FT                   cytoskeleton organization [PMID:7891662]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0031532 actin
FT                   cytoskeleton reorganization [PMID:7891662]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0042594 response
FT                   to starvation [PMID:1776363]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0051666 actin
FT                   cortical patch localization [PMID:8590801]"
FT                   /experiment="EXISTENCE:physical interaction:GO:0008092
FT                   cytoskeletal protein binding [PMID:10388809]"
FT                   /experiment="EXISTENCE:physical interaction:GO:1990528
FT                   Rvs161p-Rvs167p complex [PMID:20610658]"
FT                   /protein_id="DAA07487.1"
FT                   /translation="MSWEGFKKAINRAGHSVIIKNVDKTIDKEYDMEERRYKVLQRAGE
FT                   ALQKEAKGFLDSLRAVTASQTTIAEVISNLYDDSKYVAGGGYNVGNYYLQCVQDFDSET
FT                   VKQLDGPLRETVLDPITKFSTYFKEIEEAIKKRDHKKQDFDAAKAKVRRLVDKPAKDAS
FT                   KLPRAEKELSLAKDIFENLNNQLKTELPQLVSLRVPYFDPSFEALIKIQLRFCTDGYTR
FT                   LAQIQQYLDQQSRDDYANGLLDTKIEELLGQMTSLDICALGIK"
FT   rep_origin      132043..132120
FT                   /note="ARS309; Autonomously Replicating Sequence on
FT                   Chromosome III"
FT   gene            complement(132273..133124)
FT                   /gene="ADY2"
FT                   /gene_synonym="ATO1"
FT                   /locus_tag="YCR010C"
FT   mRNA            complement(132273..133124)
FT                   /gene="ADY2"
FT                   /gene_synonym="ATO1"
FT                   /locus_tag="YCR010C"
FT                   /product="Ady2p"
FT   CDS_pept        complement(132273..133124)
FT                   /codon_start=1
FT                   /gene="ADY2"
FT                   /gene_synonym="ATO1"
FT                   /locus_tag="YCR010C"
FT                   /product="Ady2p"
FT                   /note="Acetate transporter required for normal sporulation;
FT                   phosphorylated in mitochondria; ADY2 has a paralog, ATO2,
FT                   that arose from the whole genome duplication"
FT                   /db_xref="GOA:P25613"
FT                   /db_xref="InterPro:IPR000791"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25613"
FT                   /experiment="EXISTENCE:direct assay:GO:0005739
FT                   mitochondrion [PMID:14576278|PMID:16823961]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005886 plasma
FT                   membrane [PMID:17395151|PMID:16622836]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006846 acetate
FT                   transport [PMID:14968426]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0008519 ammonium
FT                   transmembrane transporter activity [PMID:12429834]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0015123 acetate
FT                   transmembrane transporter activity [PMID:14968426]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0015696 ammonium
FT                   transport [PMID:12429834]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0019740 nitrogen
FT                   utilization [PMID:12429834]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0055085
FT                   transmembrane transport [PMID:14968426]"
FT                   /protein_id="DAA07488.1"
FT                   /translation="MSDKEQTSGNTDLENAPAGYYSSHDNDVNGVAEDERPSHDSLGKI
FT                   YTGGDNNEYIYIGRQKFLKSDLYQAFGGTLNPGLAPAPVHKFANPAPLGLSAFALTTFV
FT                   LSMFNARAQGITVPNVVVGCAMFYGGLVQLIAGIWEIALENTFGGTALCSYGGFWLSFA
FT                   AIYIPWFGILEAYEDNESDLNNALGFYLLGWAIFTFGLTVCTMKSTVMFFLLFFLLALT
FT                   FLLLSIGHFANRLGVTRAGGVLGVVVAFIAWYNAYAGVATKQNSYVLARPFPLPSTERV
FT                   IF"
FT   gene            complement(133724..136873)
FT                   /gene="ADP1"
FT                   /locus_tag="YCR011C"
FT   mRNA            complement(133724..136873)
FT                   /gene="ADP1"
FT                   /locus_tag="YCR011C"
FT                   /product="putative ATP-dependent permease ADP1"
FT   CDS_pept        complement(133724..136873)
FT                   /codon_start=1
FT                   /gene="ADP1"
FT                   /locus_tag="YCR011C"
FT                   /product="putative ATP-dependent permease ADP1"
FT                   /note="Putative ATP-dependent permease of the ABC
FT                   transporter family"
FT                   /db_xref="GOA:P25371"
FT                   /db_xref="InterPro:IPR003439"
FT                   /db_xref="InterPro:IPR003593"
FT                   /db_xref="InterPro:IPR013032"
FT                   /db_xref="InterPro:IPR013525"
FT                   /db_xref="InterPro:IPR017871"
FT                   /db_xref="InterPro:IPR027417"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25371"
FT                   /experiment="EXISTENCE:direct assay:GO:0000324 fungal-type
FT                   vacuole [PMID:26928762]"
FT                   /experiment="EXISTENCE:direct assay:GO:0000329 fungal-type
FT                   vacuole membrane [PMID:19001347]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
FT                   [PMID:11914276]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
FT                   reticulum [PMID:11914276]"
FT                   /protein_id="DAA07489.1"
FT                   /translation="MGSHRRYLYYSILSFLLLSCSVVLAKQDKTPFFEGTSSKNSRLTA
FT                   QDKGNDTCPPCFNCMLPIFECKQFSECNSYTGRCECIEGFAGDDCSLPLCGGLSPDESG
FT                   NKDRPIRAQNDTCHCDNGWGGINCDVCQEDFVCDAFMPDPSIKGTCYKNGMIVDKVFSG
FT                   CNVTNEKILQILNGKIPQITFACDKPNQECNFQFWIDQLESFYCGLSDCAFEYDLEQNT
FT                   SHYKCNDVQCKCVPDTVLCGAKGSIDISDFLTETIKGPGDFSCDLETRQCKFSEPSMND
FT                   LILTVFGDPYITLKCESGECVHYSEIPGYKSPSKDPTVSWQGKLVLALTAVMVLALFTF
FT                   ATFYISKSPLFRNGLGSSKSPIRLPDEDAVNNFLQNEDDTLATLSFENITYSVPSINSD
FT                   GVEETVLNEISGIVKPGQILAIMGGSGAGKTTLLDILAMKRKTGHVSGSIKVNGISMDR
FT                   KSFSKIIGFVDQDDFLLPTLTVFETVLNSALLRLPKALSFEAKKARVYKVLEELRIIDI
FT                   KDRIIGNEFDRGISGGEKRRVSIACELVTSPLVLFLDEPTSGLDASNANNVIECLVRLS
FT                   SDYNRTLVLSIHQPRSNIFYLFDKLVLLSKGEMVYSGNAKKVSEFLRNEGYICPDNYNI
FT                   ADYLIDITFEAGPQGKRRRIRNISDLEAGTDTNDIDNTIHQTTFTSSDGTTQREWAHLA
FT                   AHRDEIRSLLRDEEDVEGTDGRRGATEIDLNTKLLHDKYKDSVYYAELSQEIEEVLSEG
FT                   DEESNVLNGDLPTGQQSAGFLQQLSILNSRSFKNMYRNPKLLLGNYLLTILLSLFLGTL
FT                   YYNVSNDISGFQNRMGLFFFILTYFGFVTFTGLSSFALERIIFIKERSNNYYSPLAYYI
FT                   SKIMSEVVPLRVVPPILLSLIVYPMTGLNMKDNAFFKCIGILILFNLGISLEILTIGII
FT                   FEDLNNSIILSVLVLLGSLLFSGLFINTKNITNVAFKYLKNFSVFYYAYESLLINEVKT
FT                   LMLKERKYGLNIEVPGATILSTFGFVVQNLVFDIKILALFNVVFLIMGYLALKWIVVEQ
FT                   K"
FT   gene            137746..138996
FT                   /gene="PGK1"
FT                   /locus_tag="YCR012W"
FT   mRNA            137746..138996
FT                   /gene="PGK1"
FT                   /locus_tag="YCR012W"
FT                   /product="phosphoglycerate kinase"
FT   CDS_pept        137746..138996
FT                   /codon_start=1
FT                   /gene="PGK1"
FT                   /locus_tag="YCR012W"
FT                   /product="phosphoglycerate kinase"
FT                   /EC_number="2.7.2.3"
FT                   /note="3-phosphoglycerate kinase; catalyzes transfer of
FT                   high-energy phosphoryl groups from the acyl phosphate of
FT                   1,3-bisphosphoglycerate to ADP to produce ATP; key enzyme
FT                   in glycolysis and gluconeogenesis"
FT                   /db_xref="GOA:P00560"
FT                   /db_xref="InterPro:IPR001576"
FT                   /db_xref="InterPro:IPR015824"
FT                   /db_xref="InterPro:IPR015911"
FT                   /db_xref="InterPro:IPR036043"
FT                   /db_xref="PDB:1FW8"
FT                   /db_xref="PDB:1QPG"
FT                   /db_xref="PDB:3PGK"
FT                   /db_xref="UniProtKB/Swiss-Prot:P00560"
FT                   /experiment="EXISTENCE:direct assay:GO:0004618
FT                   phosphoglycerate kinase activity [PMID:6254992]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
FT                   [PMID:27385335|PMID:11914276]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005739
FT                   mitochondrion [PMID:16962558|PMID:16823961|PMID:24769239]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005886 plasma
FT                   membrane [PMID:16622836]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006094
FT                   gluconeogenesis [PMID:400791]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006096
FT                   glycolytic process [PMID:400791]"
FT                   /protein_id="DAA07490.1"
FT                   /translation="MSLSSKLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALP
FT                   TIKYVLEHHPRYVVLASHLGRPNGERNEKYSLAPVAKELQSLLGKDVTFLNDCVGPEVE
FT                   AAVKASAPGSVILLENLRYHIEEEGSRKVDGQKVKASKEDVQKFRHELSSLADVYINDA
FT                   FGTAHRAHSSMVGFDLPQRAAGFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLI
FT                   DNLLDKVDSIIIGGGMAFTFKKVLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLP
FT                   VDFIIADAFSADANTKTVTDKEGIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGV
FT                   FEFEKFAAGTKALLDEVVKSSAAGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLE
FT                   LLEGKELPGVAFLSEKK"
FT   gene            complement(139185..140933)
FT                   /gene="POL4"
FT                   /locus_tag="YCR014C"
FT   mRNA            complement(139185..140933)
FT                   /gene="POL4"
FT                   /locus_tag="YCR014C"
FT                   /product="DNA-directed DNA polymerase IV"
FT   CDS_pept        complement(139185..140933)
FT                   /codon_start=1
FT                   /gene="POL4"
FT                   /locus_tag="YCR014C"
FT                   /product="DNA-directed DNA polymerase IV"
FT                   /EC_number="2.7.7.7"
FT                   /note="DNA polymerase IV; undergoes pair-wise interactions
FT                   with Dnl4p-Lif1p and Rad27p to mediate repair of DNA
FT                   double-strand breaks by non-homologous end joining (NHEJ);
FT                   homologous to mammalian DNA polymerase beta"
FT                   /db_xref="GOA:P25615"
FT                   /db_xref="InterPro:IPR002008"
FT                   /db_xref="InterPro:IPR002054"
FT                   /db_xref="InterPro:IPR010996"
FT                   /db_xref="InterPro:IPR019843"
FT                   /db_xref="InterPro:IPR022312"
FT                   /db_xref="InterPro:IPR027421"
FT                   /db_xref="InterPro:IPR028207"
FT                   /db_xref="InterPro:IPR029398"
FT                   /db_xref="InterPro:IPR037160"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25615"
FT                   /experiment="EXISTENCE:curator inference:GO:0005634 nucleus
FT                   [PMID:8265341]"
FT                   /experiment="EXISTENCE:direct assay:GO:0003887 DNA-directed
FT                   DNA polymerase activity [PMID:8265341]"
FT                   /experiment="EXISTENCE:direct assay:GO:0006302
FT                   double-strand break repair [PMID:12235149]"
FT                   /experiment="EXISTENCE:direct assay:GO:0006303
FT                   double-strand break repair via nonhomologous end joining
FT                   [PMID:10438542|PMID:15342630]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006303
FT                   double-strand break repair via nonhomologous end joining
FT                   [PMID:10438542]"
FT                   /protein_id="DAA07491.1"
FT                   /translation="MSLKGKFFAFLPNPNTSSNKFFKSILEKKGATIVSSIQNCLQSSR
FT                   KEVVILIEDSFVDSDMHLTQKDIFQREAGLNDVDEFLGKIEQSGIQCVKTSCITKWVQN
FT                   DKFAFQKDDLIKFQPSIIVISDNADDGQSSTDKESEISTDVESERNDDSNNKDMIQASK
FT                   PLKRLLQGDKGRASLVTDKTKYKNNELIIGALKRLTKKYEIEGEKFRARSYRLAKQSME
FT                   NCDFNVRSGEEAHTKLRNIGPSIAKKIQVILDTGVLPGLNDSVGLEDKLKYFKNCYGIG
FT                   SEIAKRWNLLNFESFCVAAKKDPEEFVSDWTILFGWSYYDDWLCKMSRNECFTHLKKVQ
FT                   KALRGIDPECQVELQGSYNRGYSKCGDIDLLFFKPFCNDTTELAKIMETLCIKLYKDGY
FT                   IHCFLQLTPNLEKLFLKRIVERFRTAKIVGYGERKRWYSSEIIKKFFMGVKLSPRELEE
FT                   LKEMKNDEGTLLIEEEEEEETKLKPIDQYMSLNAKDGNYCRRLDFFCCKWDELGAGRIH
FT                   YTGSKEYNRWIRILAAQKGFKLTQHGLFRNNILLESFNERRIFELLNLKYAEPEHRNIE
FT                   WEKKTA"
FT   gene            complement(141217..142170)
FT                   /gene="CTO1"
FT                   /locus_tag="YCR015C"
FT   mRNA            complement(141217..142170)
FT                   /gene="CTO1"
FT                   /locus_tag="YCR015C"
FT                   /product="Cto1p"
FT   CDS_pept        complement(141217..142170)
FT                   /codon_start=1
FT                   /gene="CTO1"
FT                   /locus_tag="YCR015C"
FT                   /product="Cto1p"
FT                   /note="Protein required for cold tolerance; involved in
FT                   phosphate uptake; YCR015C is not an essential gene"
FT                   /db_xref="GOA:P25616"
FT                   /db_xref="InterPro:IPR023214"
FT                   /db_xref="InterPro:IPR036412"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25616"
FT                   /experiment="EXISTENCE:direct assay:GO:0042131 thiamine
FT                   phosphate phosphatase activity [PMID:26071590]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006817
FT                   phosphate ion transport [PMID:25725023]"
FT                   /protein_id="DAA07492.1"
FT                   /translation="MKTIIISDFDETITRVDTICTIAKLPYLLNPRLKPEWGHFTKTYM
FT                   DGYHKYKYNGTRSLPLLSSGVPTIISQSNFNKLFADELKYQNHNRVVELNSVNEITKQQ
FT                   IFKSISLDQMKTFARDQNHEDCLLRDGFKTFCSSVVKNFESDFYVLSINWSKEFIHEVI
FT                   GDRRLKNSHIFCNDLKKVSDKCSQSYNGEFDCRLLTGSDKVKILGEILDKIDSGCNKEG
FT                   NSCSYWYIGDSETDLLSILHPSTNGVLLINPQENPSKFIKITEKIIGIPKDKISSFEAD
FT                   NGPAWLQFCEKEGGKGAYLVKSWDSLKDLIMQVTKM"
FT   gene            complement(142364..142546)
FT                   /locus_tag="snR33"
FT   ncRNA           complement(142364..142546)
FT                   /locus_tag="snR33"
FT                   /product="SNR33"
FT                   /note="snoRNA gene; H/ACA box small nucleolar RNA (snoRNA);
FT                   guides pseudouridylation of large subunit (LSU) rRNA at
FT                   position U1042"
FT                   /experiment="EXISTENCE:curator inference:GO:0005730
FT                   nucleolus [PMID:9160748]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0030559 rRNA
FT                   pseudouridylation guide activity [PMID:9160748]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0031118 rRNA
FT                   pseudouridine synthesis [PMID:9160748]"
FT                   /experiment="EXISTENCE:physical interaction:GO:0031429 box
FT                   H/ACA snoRNP complex [PMID:15923376|PMID:9472021]"
FT                   /ncRNA_class="other"
FT   gene            complement(142701..142771)
FT                   /gene="SUF16"
FT                   /locus_tag="tG(GCC)C"
FT   tRNA            complement(142701..142771)
FT                   /gene="SUF16"
FT                   /locus_tag="tG(GCC)C"
FT                   /product="tRNA-Gly"
FT                   /note="tG(GCC)C; Glycine tRNA (tRNA-Gly), predicted by
FT                   tRNAscan-SE analysis;can mutate to suppress +1 frameshift
FT                   mutations in glycine codons"
FT                   /experiment="EXISTENCE:curator inference:GO:0005829 cytosol
FT                   [PMID:9023104]"
FT                   /experiment="EXISTENCE:curator inference:GO:0006414
FT                   translational elongation [PMID:9023104]"
FT                   /experiment="EXISTENCE:direct assay:GO:0030371 translation
FT                   repressor activity [PMID:27609601]"
FT                   /experiment="EXISTENCE:direct assay:GO:0043022 ribosome
FT                   binding [PMID:27609601]"
FT                   /experiment="EXISTENCE:direct assay:GO:0043555 regulation
FT                   of translation in response to stress [PMID:27609601]"
FT   repeat_region   complement(142758..143080)
FT                   /rpt_type=LONG_TERMINAL_REPEAT
FT                   /note="Ty1 LTR"
FT   gene            143634..144506
FT                   /locus_tag="YCR016W"
FT   mRNA            143634..144506
FT                   /locus_tag="YCR016W"
FT                   /product="hypothetical protein"
FT   CDS_pept        143634..144506
FT                   /codon_start=1
FT                   /locus_tag="YCR016W"
FT                   /product="hypothetical protein"
FT                   /note="hypothetical protein; green fluorescent protein
FT                   (GFP)-fusion protein localizes to the nucleolus and
FT                   nucleus; predicted to be involved in ribosome biogenesis"
FT                   /db_xref="GOA:P25617"
FT                   /db_xref="InterPro:IPR019327"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25617"
FT                   /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
FT                   [PMID:14562095]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005730 nucleolus
FT                   [PMID:14562095]"
FT                   /protein_id="DAA07493.1"
FT                   /translation="MSENHVPAWKRIALKRQTISSGDESKEKGQSNLIDDDPLNITTHL
FT                   STGNLTKKEKKRIINGESKSSTKKGKRVSKPGTKKKEKLSKDEKNSKKNKILKDQLRYL
FT                   IEFFRTKSESKFPTGILELESVKENYGDSLIKDEPSESGVVEVWKFSKQKQNWLIKHFF
FT                   NLDEIPSVYNDLLLLYFRDLQGKSKEELISKCKGKLKQWNDYVEDQETKIKALIAEDKA
FT                   SEPINGEEKEEGEKDGNAEQGKQKEVQDEQEEVQMPNKELVQRSLKLLEIWKNDDSEQI
FT                   ELKNFFVDV"
FT   gene            complement(144773..147634)
FT                   /gene="CWH43"
FT                   /locus_tag="YCR017C"
FT   mRNA            complement(144773..147634)
FT                   /gene="CWH43"
FT                   /locus_tag="YCR017C"
FT                   /product="Cwh43p"
FT   CDS_pept        complement(144773..147634)
FT                   /codon_start=1
FT                   /gene="CWH43"
FT                   /locus_tag="YCR017C"
FT                   /product="Cwh43p"
FT                   /note="GPI lipid remodelase; responsible for introducing
FT                   ceramides into GPI anchors having a C26:0 fatty acid in
FT                   sn-2 of the glycerol moiety; can also use lyso-GPI protein
FT                   anchors and various base resistant lipids as substrates;
FT                   contains 14-16 transmembrane segments and several putative
FT                   glycosylation and phosphorylation sites; null mutation is
FT                   synthetically lethal with pkc1 deletion"
FT                   /db_xref="GOA:P25618"
FT                   /db_xref="InterPro:IPR019402"
FT                   /db_xref="InterPro:IPR027317"
FT                   /db_xref="InterPro:IPR036691"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25618"
FT                   /experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
FT                   reticulum [PMID:26928762]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005887 integral
FT                   component of plasma membrane [PMID:11427965]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005934 cellular bud
FT                   tip [PMID:11427965]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005935 cellular bud
FT                   neck [PMID:11427965]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006505 GPI
FT                   anchor metabolic process [PMID:27462707]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006506 GPI
FT                   anchor biosynthetic process [PMID:17714445|PMID:17761529]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0031505
FT                   fungal-type cell wall organization [PMID:11427965]"
FT                   /protein_id="DAA07494.1"
FT                   /translation="MLIINGKIIPIAHTICAFSAFFAALVTGYSLHFHKIVTNAHYTYP
FT                   DEWFPSVSATIGDRYPERSIFQILIALTAFPRFLLLLGHYYLNQSKVCFLVGVLRTVSC
FT                   GGWVYITSTDDHDIHDIFMITYIVLTLPWDIMITRYSSPLTSKNKGLTATIFFGTLFPM
FT                   IYWYIQHSVQQRAGAYSIYAYFEWSLILLDIAFDAFAYADFKKIDIVLAFNEKPGNTSF
FT                   FQIRDSSPINYGEEKSSELQKSGEKKVEKEKPVARSATGSYFRFDSFFYLLTNIFNGFL
FT                   FWSNVTSLLCSIWHFPLWYMGISGYEAAILGYLGPIFLYLPFVSEAFTQYGVLLGGIIA
FT                   IGAYIVQMPELRLISVAVGTSITVATFVQNLRYITNAETSFSFALTWLLGLVASVILKM
FT                   GFYTNNPTWVILDERNGGYNKTALVLTVLFGMLSPYVNSINFEGKRNAQAKSASLIGKL
FT                   FLAVGFGSLLFGIHQLLTDSSTTIYWAWEGYNESHGPLPWPWGALTCTVMLFASLSSVK
FT                   FMGKPLVPCLLLLISTAVLSARSITQWPKYIFGGLLYAIAMLWLVPSYFSALGQVQNIW
FT                   VYVLSFSVYIIFVLAHVWVVAYAFVPMGWVLREKIETVLAFSSTFIIIGALTCKNLNIQ
FT                   LVTMGKKFFIYVFFFAVALLSLTARFVYDIRPTGIPQPYHPDSQLITAGIWTIHFGLDN
FT                   DMWASEDRMINLIKDMELDVVGLLETDTQRITMGNRDLTSKLAHDLNMYADFGPGPNKH
FT                   TWGCVLLSKFPIVNSTHHLLPSPVGELAPAIHATLQTYNDTLVDVFVFHSGQEEDEEDR
FT                   RLQSNYMAKLMGNTTRPAILLSYLVVDPGEGNYNTYVSETSGMHDIDPSDDDRWCEYIL
FT                   YRGLRRTGYARVARGTITDTELQVGKFQVLSEQALVEHSDSMYEYGHMSEPEYEDMKFP
FT                   DKFLGEGERGHFYHVFDEPRYYL"
FT   gene            complement(148238..148903)
FT                   /gene="SRD1"
FT                   /locus_tag="YCR018C"
FT   mRNA            complement(148238..148903)
FT                   /gene="SRD1"
FT                   /locus_tag="YCR018C"
FT                   /product="Srd1p"
FT   CDS_pept        complement(148238..148903)
FT                   /codon_start=1
FT                   /gene="SRD1"
FT                   /locus_tag="YCR018C"
FT                   /product="Srd1p"
FT                   /note="Protein involved in the processing of pre-rRNA to
FT                   mature rRNA; contains a C2/C2 zinc finger motif; srd1
FT                   mutation suppresses defects caused by the rrp1-1 mutation"
FT                   /db_xref="GOA:P09007"
FT                   /db_xref="InterPro:IPR000679"
FT                   /db_xref="InterPro:IPR013088"
FT                   /db_xref="UniProtKB/Swiss-Prot:P09007"
FT                   /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
FT                   [PMID:14562095]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
FT                   [PMID:14562095]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0006364 rRNA
FT                   processing [PMID:2179050]"
FT                   /protein_id="DAA07495.1"
FT                   /translation="MRYNNYDNSGSSFLTRVVKKSDMEKTLLLNREIDDWKSNDKKKAY
FT                   KERGRVYASCSFIEVSFSQIRAVDVEKKIENAEQLRDLTRNIVKNKTSSLNEITPSKNR
FT                   VTSACNSERRTTSQEANNLEGYHSCAQGTSRSASITKKYSKKTTSRPKREKRQTILPNG
FT                   EIKECSKCKDTWTIQWRSGPDQNRELCSPCGLAYGKRLKKENEKKRQAADKRIDRNNP"
FT   repeat_region   149482..149809
FT                   /rpt_type=LONG_TERMINAL_REPEAT
FT                   /note="Ty1 LTR"
FT   gene            149920..149991
FT                   /locus_tag="tM(CAU)C"
FT   tRNA            149920..149991
FT                   /locus_tag="tM(CAU)C"
FT                   /product="tRNA-Met"
FT                   /note="tM(CAU)C; Methionine tRNA (tRNA-Met), predicted by
FT                   tRNAscan-SE analysis"
FT                   /experiment="EXISTENCE:curator inference:GO:0005829 cytosol
FT                   [PMID:9023104]"
FT                   /experiment="EXISTENCE:curator inference:GO:0006413
FT                   translational initiation [PMID:9023104]"
FT                   /experiment="EXISTENCE:direct assay:GO:0016282 eukaryotic
FT                   43S preinitiation complex [PMID:12008673]"
FT                   /experiment="EXISTENCE:direct assay:GO:0033290 eukaryotic
FT                   48S preinitiation complex [PMID:17242201]"
FT   repeat_region   150220..150551
FT                   /rpt_type=LONG_TERMINAL_REPEAT
FT                   /note="Ty1 LTR"
FT   repeat_region   complement(150695..151055)
FT                   /rpt_type=LONG_TERMINAL_REPEAT
FT                   /note="Ty4 LTR"
FT   gene            complement(151284..151356)
FT                   /locus_tag="tK(CUU)C"
FT   tRNA            complement(151284..151356)
FT                   /locus_tag="tK(CUU)C"
FT                   /product="tRNA-Lys"
FT                   /note="tK(CUU)C; Lysine tRNA (tRNA-Lys), predicted by
FT                   tRNAscan-SE analysis; a small portion is imported into
FT                   mitochondria via interaction with mt lysyl-tRNA synthetase
FT                   Msk1p and is necessary to decode AAG codons at high
FT                   temperature, when base modification of mt-encoded tRNA-Lys
FT                   is reduced"
FT                   /experiment="EXISTENCE:curator inference:GO:0006414
FT                   translational elongation [PMID:9023104]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005739
FT                   mitochondrion [PMID:8915539]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005829 cytosol
FT                   [PMID:8915539]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0030533 triplet
FT                   codon-amino acid adaptor activity [PMID:17560369]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0032543
FT                   mitochondrial translation [PMID:17560369]"
FT   repeat_region   151521..151851
FT                   /rpt_type=LONG_TERMINAL_REPEAT
FT                   /note="Ty1 LTR"
FT   gene            152837..153928
FT                   /gene="MAK32"
FT                   /locus_tag="YCR019W"
FT   mRNA            152837..153928
FT                   /gene="MAK32"
FT                   /locus_tag="YCR019W"
FT                   /product="Mak32p"
FT   CDS_pept        152837..153928
FT                   /codon_start=1
FT                   /gene="MAK32"
FT                   /locus_tag="YCR019W"
FT                   /product="Mak32p"
FT                   /note="Protein necessary for stability of L-A
FT                   dsRNA-containing particles"
FT                   /db_xref="GOA:P23060"
FT                   /db_xref="InterPro:IPR011611"
FT                   /db_xref="InterPro:IPR029056"
FT                   /db_xref="InterPro:IPR034094"
FT                   /db_xref="UniProtKB/Swiss-Prot:P23060"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0044419
FT                   interspecies interaction between organisms [PMID:3551911]"
FT                   /protein_id="DAA07496.1"
FT                   /translation="MMNEEDSTETKSLVITNGMFIIDDIERSKYNIHYKNVPGGGGTFA
FT                   ILGACIISSGNVTSKGLKWIVDRGSDFPKEVIREIDSWGTDVRFRDDFSRLTTKGLNYY
FT                   EGSDDLRKFKFLTPKKQINVDDWISTFGQKIIDEMHAFHLLCSGSRCLDIINDLLRVKS
FT                   SKGTKPIVIWEPFPDLCDFDHQNDIKSVMQRNDVTVILSPNAEESSRLFGLSSKEPTSL
FT                   EECLALAHRFDDFMDENNMCILRCGALGSISVSEKFKNGRTYDHFPAYHFKTQSKVLDP
FT                   TGGGNSFLGGFAVSYALTKSLDIASICGNIAAGAIIEQFGIPRYDPIAKTWNGITFLDR
FT                   LKFYLSQSGLQYNINDLYKSLTR"
FT   gene            complement(154012..154659)
FT                   /gene="PET18"
FT                   /gene_synonym="HIT2"
FT                   /locus_tag="YCR020C"
FT   mRNA            complement(154012..154659)
FT                   /gene="PET18"
FT                   /gene_synonym="HIT2"
FT                   /locus_tag="YCR020C"
FT                   /product="Pet18p"
FT   CDS_pept        complement(154012..154659)
FT                   /codon_start=1
FT                   /gene="PET18"
FT                   /gene_synonym="HIT2"
FT                   /locus_tag="YCR020C"
FT                   /product="Pet18p"
FT                   /note="hypothetical protein; has weak similarity to
FT                   proteins involved in thiamin metabolism; expression is
FT                   induced in the absence of thiamin"
FT                   /db_xref="GOA:P25362"
FT                   /db_xref="InterPro:IPR004305"
FT                   /db_xref="InterPro:IPR016084"
FT                   /db_xref="InterPro:IPR026285"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25362"
FT                   /experiment="EXISTENCE:direct assay:GO:0005829 cytosol
FT                   [PMID:16850348]"
FT                   /experiment="EXISTENCE:expression pattern:GO:0006772
FT                   thiamine metabolic process [PMID:10383756]"
FT                   /protein_id="DAA07497.1"
FT                   /translation="MSCTTDKLIQKYDALVRKTTEHKFAKELCAGTLKDRSLYIYLSQD
FT                   LQFFETSLRLICKTTSLAPTTHALITLAKKIGFFSNDENSYFHDCLELLAPSLTKEERD
FT                   NFDNKAIPGVDAYINFLDELRKDASITWPSLVTSLWVAEELYWRWARDTPRAPGLHWKY
FT                   QKWIDLHDGEHFQTWCEFLKAEVDKFPVEEVESIFVKVSQFEFEFFESCYNA"
FT   gene            complement(154830..155096)
FT                   /gene="MAK31"
FT                   /gene_synonym="LSM9"
FT                   /gene_synonym="NAA38"
FT                   /gene_synonym="SMX1"
FT                   /locus_tag="YCR020C-A"
FT   mRNA            complement(154830..155096)
FT                   /gene="MAK31"
FT                   /gene_synonym="LSM9"
FT                   /gene_synonym="NAA38"
FT                   /gene_synonym="SMX1"
FT                   /locus_tag="YCR020C-A"
FT                   /product="Mak31p"
FT   CDS_pept        complement(154830..155096)
FT                   /codon_start=1
FT                   /gene="MAK31"
FT                   /gene_synonym="LSM9"
FT                   /gene_synonym="NAA38"
FT                   /gene_synonym="SMX1"
FT                   /locus_tag="YCR020C-A"
FT                   /product="Mak31p"
FT                   /note="Non-catalytic subunit of N-terminal
FT                   acetyltransferase of the NatC type; required for
FT                   replication of dsRNA virus; member of the Sm protein
FT                   family"
FT                   /db_xref="GOA:P23059"
FT                   /db_xref="InterPro:IPR001163"
FT                   /db_xref="InterPro:IPR010920"
FT                   /db_xref="InterPro:IPR034110"
FT                   /db_xref="UniProtKB/Swiss-Prot:P23059"
FT                   /experiment="EXISTENCE:direct assay:GO:0031417 NatC complex
FT                   [PMID:10504710]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0004596 peptide
FT                   alpha-N-acetyltransferase activity [PMID:11274203]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006474
FT                   N-terminal protein amino acid acetylation [PMID:11274203]"
FT                   /protein_id="DAA07498.1"
FT                   /translation="MDILKLSDFIGNTLIVSLTEDRILVGSLVAVDAQMNLLLDHVEER
FT                   MGSSSRMMGLVSVPRRSVKTIMIDKPVLQELTANKVELMANIV"
FT   gene            155320..155556
FT                   /gene="HTL1"
FT                   /locus_tag="YCR020W-B"
FT   mRNA            155320..155556
FT                   /gene="HTL1"
FT                   /locus_tag="YCR020W-B"
FT                   /product="Htl1p"
FT   CDS_pept        155320..155556
FT                   /codon_start=1
FT                   /gene="HTL1"
FT                   /locus_tag="YCR020W-B"
FT                   /product="Htl1p"
FT                   /note="Component of the RSC chromatin remodeling complex;
FT                   RSC functions in transcriptional regulation and elongation,
FT                   chromosome stability, and establishing sister chromatid
FT                   cohesion; involved in telomere maintenance"
FT                   /db_xref="GOA:Q9URQ5"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q9URQ5"
FT                   /experiment="EXISTENCE:curator inference:GO:0003682
FT                   chromatin binding [PMID:12417720]"
FT                   /experiment="EXISTENCE:curator inference:GO:0006338
FT                   chromatin remodeling [PMID:12417720]"
FT                   /experiment="EXISTENCE:direct assay:GO:0006337 nucleosome
FT                   disassembly [PMID:16492771]"
FT                   /experiment="EXISTENCE:direct assay:GO:0006368
FT                   transcription elongation from RNA polymerase II promoter
FT                   [PMID:17081996]"
FT                   /experiment="EXISTENCE:direct assay:GO:0015616 DNA
FT                   translocase activity
FT                   [PMID:16455496|PMID:17188033|PMID:17918861]"
FT                   /experiment="EXISTENCE:direct assay:GO:0016586 RSC-type
FT                   complex [PMID:12417720]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006974 cellular
FT                   response to DNA damage stimulus [PMID:12482937]"
FT                   /protein_id="DAA07499.1"
FT                   /translation="MSQNNTISSMNPERAYNNVTLKNLTAFQLLSQRENICELLNLVES
FT                   TERHNSIINPERQRMSLEEMKKMLDALKNERKK"
FT   gene            complement(156109..157107)
FT                   /gene="HSP30"
FT                   /gene_synonym="YRO1"
FT                   /locus_tag="YCR021C"
FT   mRNA            complement(156109..157107)
FT                   /gene="HSP30"
FT                   /gene_synonym="YRO1"
FT                   /locus_tag="YCR021C"
FT                   /product="Hsp30p"
FT   CDS_pept        complement(156109..157107)
FT                   /codon_start=1
FT                   /gene="HSP30"
FT                   /gene_synonym="YRO1"
FT                   /locus_tag="YCR021C"
FT                   /product="Hsp30p"
FT                   /note="Negative regulator of the H(+)-ATPase Pma1p;
FT                   stress-responsive protein; hydrophobic plasma membrane
FT                   localized; induced by heat shock, ethanol treatment, weak
FT                   organic acid, glucose limitation, and entry into stationary
FT                   phase"
FT                   /db_xref="GOA:P25619"
FT                   /db_xref="InterPro:IPR001425"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25619"
FT                   /experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
FT                   reticulum [PMID:26928762]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005886 plasma
FT                   membrane [PMID:1535043|PMID:16622836]"
FT                   /experiment="EXISTENCE:expression pattern:GO:0006974
FT                   cellular response to DNA damage stimulus [PMID:10206703]"
FT                   /experiment="EXISTENCE:expression pattern:GO:0034605
FT                   cellular response to heat [PMID:10206703]"
FT                   /experiment="EXISTENCE:expression pattern:GO:0070301
FT                   cellular response to hydrogen peroxide [PMID:10206703]"
FT                   /experiment="EXISTENCE:expression pattern:GO:0071361
FT                   cellular response to ethanol [PMID:10206703]"
FT                   /experiment="EXISTENCE:expression pattern:GO:0071470
FT                   cellular response to osmotic stress [PMID:10206703]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0032780 negative
FT                   regulation of ATPase activity [PMID:9250391]"
FT                   /protein_id="DAA07500.1"
FT                   /translation="MNDTLSSFLNRNEALGLNPPHGLDMHITKRGSDWLWAVFAVFGFI
FT                   LLCYVVMFFIAENKGSRLTRYALAPAFLITFFEFFAFFTYASDLGWTGVQAEFNHVKVS
FT                   KSITGEVPGIRQIFYSKYIAWFLSWPCLLFLIELAASTTGENDDISALDMVHSLLIQIV
FT                   GTLFWVVSLLVGSLIKSTYKWGYYTIGAVAMLVTQGVICQRQFFNLKTRGFNALMLCTC
FT                   MVIVWLYFICWGLSDGGNRIQPDGEAIFYGVLDLCVFAIYPCYLLIAVSRDGKLPRLSL
FT                   TGGFSHHHATDDVEDAAPETKEAVPESPRASGETAIHEPEPEAEQAVEDTA"
FT   gene            complement(157421..157765)
FT                   /locus_tag="YCR022C"
FT   mRNA            complement(157421..157765)
FT                   /locus_tag="YCR022C"
FT                   /product="hypothetical protein"
FT   CDS_pept        complement(157421..157765)
FT                   /codon_start=1
FT                   /locus_tag="YCR022C"
FT                   /product="hypothetical protein"
FT                   /note="hypothetical protein; conserved among S. cerevisiae
FT                   strains; YCR022C is not an essential gene"
FT                   /db_xref="GOA:P25620"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25620"
FT                   /protein_id="DAA80270.1"
FT                   /translation="MENRCSNPCYIQSDPSDLLSLRLPARFCWPFSRSSRIFQGSSRRR
FT                   ILSEGKNASKACFVRIFGMAKVSKAISRSRSRLLFRSLPPHPACLFEYQISSSSLFHHP
FT                   FLLWQGQVFF"
FT   gene            complement(158538..160373)
FT                   /locus_tag="YCR023C"
FT   mRNA            complement(158538..160373)
FT                   /locus_tag="YCR023C"
FT                   /product="hypothetical protein"
FT   CDS_pept        complement(158538..160373)
FT                   /codon_start=1
FT                   /locus_tag="YCR023C"
FT                   /product="hypothetical protein"
FT                   /note="Vacuolar membrane hypothetical protein; member of
FT                   the multidrug resistance family; YCR023C is not an
FT                   essential gene"
FT                   /db_xref="GOA:P25351"
FT                   /db_xref="InterPro:IPR011701"
FT                   /db_xref="InterPro:IPR020846"
FT                   /db_xref="InterPro:IPR036259"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25351"
FT                   /experiment="EXISTENCE:direct assay:GO:0000329 fungal-type
FT                   vacuole membrane [PMID:12562762]"
FT                   /protein_id="DAA07501.1"
FT                   /translation="MARQKLTFKEQMDGFPWVQLVVVSLVRFSEPIAFSSLFPYVYFMV
FT                   RDFNIAPNDAQVSKYSGYLSSSFALCQVISAYHWGRFSEKHGRKITLTCGLIGTSVSLL
FT                   ILGFSRNFYQALVARSLMGLLNGNVGVIRTIIGEIATERKHQALAFSTMPLLFQFGAVV
FT                   GPMIGGFLVFRDGTMNEVPLWFPHFAKRIIRSYPYALPNVVVCMFLMFGLTNATLFLEE
FT                   THPAFKDRRDYGLEVGDFIKKNIFGIQPKRRPWQKRIQDDSENIHHRNENVNSIRGQDS
FT                   EEDENSPLVNTTNDDDTESIQSIDPILTRRQSVGLIRTYSLHEPTDAVHANIDTAPDGC
FT                   KESSIFHHVFHTKVFYPISVNFIMALHLIVYNEFLPVFLAYDLAVDPENPKKLASKFPW
FT                   KISGGIGYEPEQTGTLLSTTGIFGCFVVIFIFPIVDRNFDCLTIFRTLVKLYPIMYVMV
FT                   PYVVFLQNERIPSWYTVVYLYIITGIKTFCGALTSPQIMLLIHNSSPLSCRSVINGATI
FT                   SISASARFIGPLVWGYIMSWSQQNDVAWVSWWSLSLFCMVALYQSYKIAPIDDNENELH
FT                   GQGSEDAYNSQSQSSDLRMAHRSSLSSLSNQRCTT"
FT   gene            complement(160744..162222)
FT                   /gene="SLM5"
FT                   /locus_tag="YCR024C"
FT   mRNA            complement(160744..162222)
FT                   /gene="SLM5"
FT                   /locus_tag="YCR024C"
FT                   /product="asparagine--tRNA ligase SLM5"
FT   CDS_pept        complement(160744..162222)
FT                   /codon_start=1
FT                   /gene="SLM5"
FT                   /locus_tag="YCR024C"
FT                   /product="asparagine--tRNA ligase SLM5"
FT                   /EC_number="6.1.1.22"
FT                   /note="Mitochondrial asparaginyl-tRNA synthetase"
FT                   /db_xref="GOA:P25345"
FT                   /db_xref="InterPro:IPR002312"
FT                   /db_xref="InterPro:IPR004364"
FT                   /db_xref="InterPro:IPR004365"
FT                   /db_xref="InterPro:IPR004522"
FT                   /db_xref="InterPro:IPR006195"
FT                   /db_xref="InterPro:IPR012340"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25345"
FT                   /experiment="EXISTENCE:direct assay:GO:0004816
FT                   asparagine-tRNA ligase activity [PMID:9030748]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005739
FT                   mitochondrion [PMID:14576278|PMID:16823961|PMID:24769239]"
FT                   /experiment="EXISTENCE:direct assay:GO:0006421
FT                   asparaginyl-tRNA aminoacylation [PMID:9030748]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0005739
FT                   mitochondrion [PMID:9030748]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0070145
FT                   mitochondrial asparaginyl-tRNA aminoacylation
FT                   [PMID:9030748]"
FT                   /protein_id="DAA07502.1"
FT                   /translation="MFHAFTFLKGGRFYSSLTVKSLYEQVHHTSHDPISINGWIKSIRL
FT                   LKRIAFLDLQDGTSVNPLRIVIPLTNTDEVQFLKILKTGQTLSISNATWQSTPNRKQPF
FT                   ELQIKNPVKSIKLVGPVSENYPLQKKYQTLRYLRSLPTLKYRTAYLSAILRLRSFVEFQ
FT                   FMLYFQKNHFTKVSPPILTSNDCEGAGELFQVSTNTSPTASSYFGKPTYLTVSTQLHLE
FT                   ILALSLSRCWTLSPCFRAEKSDTPRHLSEFWMLEVEMCFVNSVNELTSFVETTIKHIIK
FT                   ACIDNQQELLPKQFISSQENNASSELSINQETQQIKTRWEDLINEKWHNITYTNAIEIL
FT                   KKRHNEVSHFKYEPKWGQPLQTEHEKFLAGEYFKSPVFVTDYPRLCKPFYMKQNSTPDD
FT                   TVGCFDLLVPGMGEIIGGSLREDDYDKLCREMKARGMNRSGELDWYVSLRKEGSAPHGG
FT                   FGLGFERFISYLYGNHNIKDAIPFYRTSAESIDF"
FT   gene            complement(162599..162865)
FT                   /locus_tag="YCR024C-B"
FT   mRNA            complement(162599..162865)
FT                   /locus_tag="YCR024C-B"
FT                   /product="hypothetical protein"
FT   CDS_pept        complement(162599..162865)
FT                   /codon_start=1
FT                   /locus_tag="YCR024C-B"
FT                   /product="hypothetical protein"
FT                   /note="hypothetical protein; identified by expression
FT                   profiling and mass spectrometry"
FT                   /db_xref="EnsemblGenomes-Gn:YCR024C-B"
FT                   /db_xref="EnsemblGenomes-Tr:YCR024C-B"
FT                   /db_xref="GOA:Q3E7Z8"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q3E7Z8"
FT                   /protein_id="DAA07503.1"
FT                   /translation="MCVCAIPFFEFFLPFIPHYAFLLFVSSVRFTVNERCYYLVCVLKL
FT                   NCAFFFMVMIFELKRVCVSYLDRSRKIQIVSFFPFITIIFFHS"
FT   gene            complement(162945..163067)
FT                   /gene="PMP1"
FT                   /locus_tag="YCR024C-A"
FT   mRNA            complement(162945..163067)
FT                   /gene="PMP1"
FT                   /locus_tag="YCR024C-A"
FT                   /product="proteolipid ATPase"
FT   CDS_pept        complement(162945..163067)
FT                   /codon_start=1
FT                   /gene="PMP1"
FT                   /locus_tag="YCR024C-A"
FT                   /product="proteolipid ATPase"
FT                   /note="Regulatory subunit for the plasma membrane
FT                   H(+)-ATPase Pma1p; small single-membrane span proteolipid;
FT                   forms unique helix and positively charged cytoplasmic
FT                   domain that is able to specifically segregate
FT                   phosphatidylserines; PMP1 has a paralog, PMP2, that arose
FT                   from the whole genome duplication"
FT                   /db_xref="GOA:P32903"
FT                   /db_xref="InterPro:IPR012589"
FT                   /db_xref="UniProtKB/Swiss-Prot:P32903"
FT                   /experiment="EXISTENCE:direct assay:GO:0005886 plasma
FT                   membrane [PMID:1532582]"
FT                   /experiment="EXISTENCE:direct assay:GO:0016020 membrane
FT                   [PMID:1532582]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0030234
FT                   enzyme regulator activity [PMID:8063750]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0032781
FT                   positive regulation of ATPase activity [PMID:8063750]"
FT                   /protein_id="DAA07504.1"
FT                   /translation="MTLPGGVILVFILVGLACIAIIATIIYRKWQARQRGLQRF"
FT   gene            complement(163446..163856)
FT                   /locus_tag="YCR025C"
FT   mRNA            complement(163446..163856)
FT                   /locus_tag="YCR025C"
FT                   /product="hypothetical protein"
FT   CDS_pept        complement(163446..163856)
FT                   /codon_start=1
FT                   /locus_tag="YCR025C"
FT                   /product="hypothetical protein"
FT                   /note="hypothetical protein; conserved across S. cerevisiae
FT                   strains; YCR025C is not an essential gene"
FT                   /db_xref="GOA:P25352"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25352"
FT                   /protein_id="DAA80271.1"
FT                   /translation="MSSFGHRAFFSCCPLLEGETLHSIKLRKEATYQTQSGWPVRWPIR
FT                   YPRALPLESHVHPYHMIVKLPHPRTQPRLFLWLSLHWTGIPFLGKPGIGRNRVKSKQFS
FT                   HFQQSKIKTTMRKKTTNRKQKAERCQYRLVTA"
FT   gene            complement(164111..166339)
FT                   /gene="NPP1"
FT                   /locus_tag="YCR026C"
FT   mRNA            complement(164111..166339)
FT                   /gene="NPP1"
FT                   /locus_tag="YCR026C"
FT                   /product="nucleotide diphosphatase/phosphodiesterase NPP1"
FT   CDS_pept        complement(164111..166339)
FT                   /codon_start=1
FT                   /gene="NPP1"
FT                   /locus_tag="YCR026C"
FT                   /product="nucleotide diphosphatase/phosphodiesterase NPP1"
FT                   /EC_number="3.6.1.9"
FT                   /EC_number="3.1.4.1"
FT                   /note="Nucleotide pyrophosphatase/phosphodiesterase;
FT                   mediates extracellular nucleotide phosphate hydrolysis
FT                   along with Npp2p and Pho5p; activity and expression
FT                   enhanced during conditions of phosphate starvation;
FT                   involved in spore wall assembly; NPP1 has a paralog, NPP2,
FT                   that arose from the whole genome duplication, and an npp1
FT                   npp2 double mutant exhibits reduced dityrosine fluorescence
FT                   relative to the single mutants"
FT                   /db_xref="GOA:P25353"
FT                   /db_xref="InterPro:IPR002591"
FT                   /db_xref="InterPro:IPR017850"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25353"
FT                   /experiment="EXISTENCE:direct assay:GO:0047429
FT                   nucleoside-triphosphate diphosphatase activity
FT                   [PMID:16278456]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0017111
FT                   nucleoside-triphosphatase activity [PMID:16278456]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0047429
FT                   nucleoside-triphosphate diphosphatase activity
FT                   [PMID:16278456]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0009141
FT                   nucleoside triphosphate metabolic process [PMID:16278456]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0016036 cellular
FT                   response to phosphate starvation [PMID:16278456]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0017111
FT                   nucleoside-triphosphatase activity [PMID:16278456]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0047429
FT                   nucleoside-triphosphate diphosphatase activity
FT                   [PMID:16278456]"
FT                   /protein_id="DAA07505.1"
FT                   /translation="MELQNDLESLDNELNDFSEDPFRDDFITDEDAVRSGWRSAWTRMK
FT                   YWFYKNRLKWTNNPIVIGDAKDSRDGSNFRRGIPLYELDANGQPIDTELVDENELSFGT
FT                   GFHSKVPFKIIFRTLFGSLVFAIFLILMINIAKPHHSTRVLSHFGSPEFDPYVKYFNGT
FT                   HEFFPLTIVISLDGFHPSLISKRNTPFLHDLYELKYDGGMNITSTPFMVPSFPTETFPN
FT                   HWTLVTGQYPIHHGIVSNVFWDPDLNEEFHPGVLDPRIWNNNDTEPIWQTVQSAFDGDI
FT                   PFKAATHMWPGSDVNYTKYNEEKLQPEHKNPIARERTPFYFDEFNAKEPLSQKLSKIIE
FT                   YVDMSTLNERPQLILGYVPNVDAFGHKHGYPSESEYYYEDFTETLGEVDTFLKQLVESL
FT                   QERNLTSFTNLVIVSDHGMSDIVVPSNVIIWEDLLDEKLRKDYVSHAYLEGPMMAISLK
FT                   DSGNINEVYHNLKTSIDEDKYTVYVNGNFPKEWNFNDGKNHHMASIWIVPEPGYAVMKK
FT                   EQLKKVAKGDHKDKNEDNVFTIGSHGYDNNAIDMRSVFIGMGPYFPQGYIEPFQNTEIY
FT                   NLLCDICGVAEKDRNSNDGTGMLMNQLREPQSSEEVEIEDDFDYLVSKFGEFSTYNIIW
FT                   GGYPEETEQDNVDNDNDDNDDGNTDEIAAMPSSSLTIKLEMTTSIPSATETLLGETSPS
FT                   SRSSSSSSIQASATASTVGDWLQDIINDAKDLIDDIIDSIDDLVDSDT"
FT   rep_origin      166503..167348
FT                   /note="ARS310; Compound autonomously replicating sequence
FT                   on Chromosome III"
FT   gene            complement(167370..167999)
FT                   /gene="RHB1"
FT                   /gene_synonym="RSG1"
FT                   /locus_tag="YCR027C"
FT   mRNA            complement(167370..167999)
FT                   /gene="RHB1"
FT                   /gene_synonym="RSG1"
FT                   /locus_tag="YCR027C"
FT                   /product="putative GTPase RHB1"
FT   CDS_pept        complement(167370..167999)
FT                   /codon_start=1
FT                   /gene="RHB1"
FT                   /gene_synonym="RSG1"
FT                   /locus_tag="YCR027C"
FT                   /product="putative GTPase RHB1"
FT                   /note="Putative Rheb-related GTPase; involved in regulating
FT                   canavanine resistance and arginine uptake; member of the
FT                   Ras superfamily of G-proteins"
FT                   /db_xref="GOA:P25378"
FT                   /db_xref="InterPro:IPR001806"
FT                   /db_xref="InterPro:IPR005225"
FT                   /db_xref="InterPro:IPR020849"
FT                   /db_xref="InterPro:IPR027417"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25378"
FT                   /experiment="EXISTENCE:direct assay:GO:0005829 cytosol
FT                   [PMID:26928762]"
FT                   /experiment="EXISTENCE:direct assay:GO:0019897 extrinsic
FT                   component of plasma membrane [PMID:10753927]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0015809
FT                   arginine transport [PMID:10753927]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0015809 arginine
FT                   transport [PMID:10753927]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0015819 lysine
FT                   transport [PMID:10753927]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0042147
FT                   retrograde transport, endosome to Golgi [PMID:17101785]"
FT                   /protein_id="DAA07506.1"
FT                   /translation="MEYATMSSSNSTHNFQRKIALIGARNVGKTTLTVRFVESRFVESY
FT                   YPTIENEFTRIIPYKSHDCTLEILDTAGQDEVSLLNIKSLTGVRGIILCYSIINRASFD
FT                   LIPILWDKLVDQLGKDNLPVILVGTKADLGRSTKGVKRCVTKAEGEKLASTIGSQDKRN
FT                   QAAFIECSAELDYNVEETFMLLLKQMERVEGTLGLDAENNNKCSIM"
FT   gene            complement(168301..168372)
FT                   /locus_tag="tQ(UUG)C"
FT   tRNA            complement(168301..168372)
FT                   /locus_tag="tQ(UUG)C"
FT                   /product="tRNA-Gln"
FT                   /note="tQ(UUG)C; Glutamine tRNA (tRNA-Gln), predicted by
FT                   tRNAscan-SE analysis; thiolation of uridine at wobble
FT                   position (34) requires Ncs6p"
FT                   /experiment="EXISTENCE:curator inference:GO:0006414
FT                   translational elongation [PMID:9023104]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005739
FT                   mitochondrion [PMID:15706032]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005829 cytosol
FT                   [PMID:15706032]"
FT   repeat_region   169573..169888
FT                   /rpt_type=LONG_TERMINAL_REPEAT
FT                   /note="Ty1 LTR"
FT   gene            complement(170886..172424)
FT                   /gene="FEN2"
FT                   /locus_tag="YCR028C"
FT   mRNA            complement(170886..172424)
FT                   /gene="FEN2"
FT                   /locus_tag="YCR028C"
FT                   /product="Fen2p"
FT   CDS_pept        complement(170886..172424)
FT                   /codon_start=1
FT                   /gene="FEN2"
FT                   /locus_tag="YCR028C"
FT                   /product="Fen2p"
FT                   /note="Plasma membrane H+-pantothenate symporter; confers
FT                   sensitivity to the antifungal agent fenpropimorph;
FT                   relocalizes from vacuole to cytoplasm upon DNA replication
FT                   stress"
FT                   /db_xref="GOA:P25621"
FT                   /db_xref="InterPro:IPR011701"
FT                   /db_xref="InterPro:IPR036259"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25621"
FT                   /experiment="EXISTENCE:direct assay:GO:0000324 fungal-type
FT                   vacuole [PMID:26928762]"
FT                   /experiment="EXISTENCE:direct assay:GO:0000329 fungal-type
FT                   vacuole membrane [PMID:22842922]"
FT                   /experiment="EXISTENCE:direct assay:GO:0071944 cell
FT                   periphery [PMID:26928762]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0005886 plasma
FT                   membrane [PMID:10373490]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006897
FT                   endocytosis [PMID:15020461]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0015233
FT                   pantothenate transmembrane transporter activity
FT                   [PMID:10373490]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0015887
FT                   pantothenate transmembrane transport [PMID:10373490]"
FT                   /protein_id="DAA07507.1"
FT                   /translation="MMKESKSITQHEVERESVSSKRAIKKRLLLFKIDLFVLSFVCLQY
FT                   WINYVDRVGFTNAYISGMKEDLKMVGNDLTVSNTVFMIGYIVGMVPNNLMLLCVPPRIW
FT                   LSFCTFAWGLLTLGMYKVTSFKHICAIRFFQALFESCTFSGTHFVLGSWYKEDELPIRS
FT                   AIFTGSGLVGSMFSGFMQTSIFTHLNGRNGLAGWRWLFIIDFCITLPIAIYGFIFFPGL
FT                   PDQTSAVSKFSMTRYIFNEQELHYARRRLPARDESTRLDWSTIPRVLKRWHWWMFSLVW
FT                   VLGGENLGFASNSTFALWLQNQKYTLAQRNNYPSGIFAVGIVSTLCSAVYMSKIPRARH
FT                   WHVSVFISLVMVIVAVLIRADPLNPKVVFSAQYLGGVAYAGQAVFFSWANIICHADLQE
FT                   RAIVLASMNMFSGAVNAWWSILFFASDMVPKFERGCYALLATAISSGIVSVVIRSLQIK
FT                   ENLSKKQVPYIDANDMPGEDDDDDNQDNENDGDDESMEVELHNEEMAEISNPFR"
FT   gene            complement(172950..173440)
FT                   /gene="RIM1"
FT                   /locus_tag="YCR028C-A"
FT   mRNA            complement(join(172950..173115,173199..173440))
FT                   /gene="RIM1"
FT                   /locus_tag="YCR028C-A"
FT                   /product="Rim1p"
FT   CDS_pept        complement(join(172950..173115,173199..173440))
FT                   /codon_start=1
FT                   /gene="RIM1"
FT                   /locus_tag="YCR028C-A"
FT                   /product="Rim1p"
FT                   /note="ssDNA-binding protein essential for mitochondrial
FT                   genome maintenance; involved in mitochondrial DNA
FT                   replication; stimulates utilization by Mip1p DNA polymerase
FT                   of RNA primers synthesized by Rpo41p"
FT                   /db_xref="GOA:P32445"
FT                   /db_xref="InterPro:IPR000424"
FT                   /db_xref="InterPro:IPR011344"
FT                   /db_xref="InterPro:IPR012340"
FT                   /db_xref="PDB:6CQK"
FT                   /db_xref="PDB:6CQM"
FT                   /db_xref="PDB:6CQO"
FT                   /db_xref="UniProtKB/Swiss-Prot:P32445"
FT                   /experiment="EXISTENCE:direct assay:GO:0003697
FT                   single-stranded DNA binding [PMID:1324172]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005739
FT                   mitochondrion
FT                   [PMID:1324172|PMID:14576278|PMID:16823961|PMID:24769239]"
FT                   /experiment="EXISTENCE:direct assay:GO:0042645
FT                   mitochondrial nucleoid [PMID:10869431]"
FT                   /experiment="EXISTENCE:direct assay:GO:0090297 positive
FT                   regulation of mitochondrial DNA replication
FT                   [PMID:26184436]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000002
FT                   mitochondrial genome maintenance [PMID:1324172]"
FT                   /protein_id="DAA07508.1"
FT                   /translation="MFLRTQARFFHATTKKMDFSKMSIVGRIGSEFTEHTSANNNRYLK
FT                   YSIASQPRRDGQTNWYNITVFNEPQINFLTEYVRKGALVYVEADAANYVFERDDGSKGT
FT                   TLSLVQKDINLLKNGKKLEDAEGQENAASSE"
FT   gene            complement(173826..176438)
FT                   /gene="SYP1"
FT                   /gene_synonym="YCR029C-A"
FT                   /locus_tag="YCR030C"
FT   mRNA            complement(173826..176438)
FT                   /gene="SYP1"
FT                   /gene_synonym="YCR029C-A"
FT                   /locus_tag="YCR030C"
FT                   /product="Syp1p"
FT   CDS_pept        complement(173826..176438)
FT                   /codon_start=1
FT                   /gene="SYP1"
FT                   /gene_synonym="YCR029C-A"
FT                   /locus_tag="YCR030C"
FT                   /product="Syp1p"
FT                   /note="Negative regulator of WASP-Arp23 complex; involved
FT                   in endocytic site formation; directly inhibits Las17p
FT                   stimulation of Arp23 complex-mediated actin assembly in
FT                   vitro; may regulate assembly and disassembly of the septin
FT                   ring; colocalizes and interacts with septin subunits;
FT                   potential role in actin cytoskeletal organization"
FT                   /db_xref="GOA:P25623"
FT                   /db_xref="InterPro:IPR018808"
FT                   /db_xref="InterPro:IPR027267"
FT                   /db_xref="InterPro:IPR028565"
FT                   /db_xref="PDB:3G9G"
FT                   /db_xref="PDB:3G9H"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25623"
FT                   /experiment="EXISTENCE:direct assay:GO:0000144 cellular bud
FT                   neck septin ring [PMID:26179915]"
FT                   /experiment="EXISTENCE:direct assay:GO:0001400 mating
FT                   projection base [PMID:11014808]"
FT                   /experiment="EXISTENCE:direct assay:GO:0004857 enzyme
FT                   inhibitor activity [PMID:19962315]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005628 prospore
FT                   membrane [PMID:24390141]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005934 cellular bud
FT                   tip [PMID:11014808]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005935 cellular bud
FT                   neck [PMID:11014808]"
FT                   /experiment="EXISTENCE:direct assay:GO:0043086 negative
FT                   regulation of catalytic activity [PMID:19962315]"
FT                   /experiment="EXISTENCE:direct assay:GO:0043332 mating
FT                   projection tip [PMID:19053807]"
FT                   /experiment="EXISTENCE:direct assay:GO:0061645 endocytic
FT                   patch [PMID:19962315]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0032185
FT                   septin cytoskeleton organization [PMID:18791237]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000147 actin
FT                   cortical patch assembly [PMID:19776351]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0032185 septin
FT                   cytoskeleton organization [PMID:18791237]"
FT                   /experiment="EXISTENCE:physical interaction:GO:0032185
FT                   septin cytoskeleton organization [PMID:18791237]"
FT                   /protein_id="DAA07509.1"
FT                   /translation="MTEQRTKYADSILTTKSPYEATETIRIRLSQVKLLNKDFYLLFKE
FT                   LANLKRNYAQQLRKIIAENEDITKILNAQMIESNVLTPQEMSAFRFNSLGELRNVWDTV
FT                   IEELKSDLKSSTEYYNTLDQQVVRELKESVENNTSWRESKDLHSKLSKNAASIEHYSKN
FT                   NENSSHLEEARRQWDQQSPYLFELFETIDYNRLDTLKNCMLRFQTSFSDYLLNTTKECE
FT                   TVMTKFLAFEPQSEIDRFAKDASQYNFQLSSSSKEVVPNNASPASATGARPVSVSNGAA
FT                   NTEREKKSPQKDKRKSAFGNIGHRLASASSSLTHNDLMNNEFSDSTNNSSLKSKKSSHT
FT                   LRSKVGSIFGRNKTKNKRQQQSSSNSHIQASITETPNNSSTRVSSTATSSIYQKQRRPT
FT                   YSSSKSNNWTPGEASDTPPLPPHATPKNVDAPVTADTPPAQTFTPSEVPPSTPQQSSPP
FT                   TAKEPDSSNLPKTVPISISQPPLQPQSKTKPLPVEPASPSISLPTATVDNQPSGQVDSR
FT                   PLHIRAPALPPSRKQNFIHNRDSQLYDSLPNHGSGATPTSSSLSSIPQERPVSTLSSQI
FT                   TGELRELNPQATGSSTSLVGQSLFQHSSLDTSQFGLNASIAEVLNASFKDGMLQNSQLI
FT                   GEIALNYLPNSVMNSPLPIGINLRINNGAKFEKVILNQAFIERVAPEEFKVNPSFIDSR
FT                   TLGAIKYSIKEPIAPIVIHPVWRFESHQASVVLTVKMSPSLPDEISQIVIEDLVVFVNI
FT                   DGANATSALSKPQGSFSKEKKRITWRFKEPVVLTRNGEGQRLIARFITDGLAHESAKGV
FT                   ITKFTISETDNVALPHSGAGSGITLTCQELDENNPFGGEWLDVNTKRTLTTGNYHGLA"
FT   gene            177183..177282
FT                   /locus_tag="snR65"
FT   ncRNA           177183..177282
FT                   /locus_tag="snR65"
FT                   /product="SNR65"
FT                   /note="snoRNA gene; C/D box small nucleolar RNA (snoRNA);
FT                   guides 2'-O-methylation of large subunit (LSU) rRNA at
FT                   position U2347"
FT                   /experiment="EXISTENCE:curator inference:GO:0005730
FT                   nucleolus [PMID:10024243]"
FT                   /experiment="EXISTENCE:curator inference:GO:0031428 box C/D
FT                   snoRNP complex [PMID:10024243]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0030562 rRNA
FT                   2'-O-ribose methylation guide activity [PMID:10024243]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0031167 rRNA
FT                   methylation [PMID:10024243]"
FT                   /ncRNA_class="other"
FT   gene            complement(177500..178220)
FT                   /gene="RPS14A"
FT                   /gene_synonym="CRY1"
FT                   /gene_synonym="RPL59"
FT                   /locus_tag="YCR031C"
FT   mRNA            complement(join(177500..177906,178214..178220))
FT                   /gene="RPS14A"
FT                   /gene_synonym="CRY1"
FT                   /gene_synonym="RPL59"
FT                   /locus_tag="YCR031C"
FT                   /product="ribosomal 40S subunit protein S14A"
FT   CDS_pept        complement(join(177500..177906,178214..178220))
FT                   /codon_start=1
FT                   /gene="RPS14A"
FT                   /gene_synonym="CRY1"
FT                   /gene_synonym="RPL59"
FT                   /locus_tag="YCR031C"
FT                   /product="ribosomal 40S subunit protein S14A"
FT                   /note="Protein component of the small (40S) ribosomal
FT                   subunit; required for ribosome assembly and 20S pre-rRNA
FT                   processing; mutations confer cryptopleurine resistance;
FT                   homologous to mammalian ribosomal protein S14 and bacterial
FT                   S11; RPS14A has a paralog, RPS14B, that arose from the
FT                   whole genome duplication"
FT                   /db_xref="GOA:P06367"
FT                   /db_xref="InterPro:IPR001971"
FT                   /db_xref="InterPro:IPR018102"
FT                   /db_xref="InterPro:IPR036967"
FT                   /db_xref="PDB:1K5X"
FT                   /db_xref="PDB:3J6X"
FT                   /db_xref="PDB:3J6Y"
FT                   /db_xref="PDB:3J77"
FT                   /db_xref="PDB:3J78"
FT                   /db_xref="PDB:4U3M"
FT                   /db_xref="PDB:4U3N"
FT                   /db_xref="PDB:4U3U"
FT                   /db_xref="PDB:4U4N"
FT                   /db_xref="PDB:4U4O"
FT                   /db_xref="PDB:4U4Q"
FT                   /db_xref="PDB:4U4R"
FT                   /db_xref="PDB:4U4U"
FT                   /db_xref="PDB:4U4Y"
FT                   /db_xref="PDB:4U4Z"
FT                   /db_xref="PDB:4U50"
FT                   /db_xref="PDB:4U51"
FT                   /db_xref="PDB:4U52"
FT                   /db_xref="PDB:4U53"
FT                   /db_xref="PDB:4U55"
FT                   /db_xref="PDB:4U56"
FT                   /db_xref="PDB:4U6F"
FT                   /db_xref="PDB:4V4B"
FT                   /db_xref="PDB:4V6I"
FT                   /db_xref="PDB:4V7R"
FT                   /db_xref="PDB:4V88"
FT                   /db_xref="PDB:4V8Y"
FT                   /db_xref="PDB:4V8Z"
FT                   /db_xref="PDB:4V92"
FT                   /db_xref="PDB:5DAT"
FT                   /db_xref="PDB:5DC3"
FT                   /db_xref="PDB:5DGE"
FT                   /db_xref="PDB:5DGF"
FT                   /db_xref="PDB:5DGV"
FT                   /db_xref="PDB:5FCI"
FT                   /db_xref="PDB:5FCJ"
FT                   /db_xref="PDB:5JPQ"
FT                   /db_xref="PDB:5JUO"
FT                   /db_xref="PDB:5JUP"
FT                   /db_xref="PDB:5JUS"
FT                   /db_xref="PDB:5JUT"
FT                   /db_xref="PDB:5JUU"
FT                   /db_xref="PDB:5LL6"
FT                   /db_xref="PDB:5LYB"
FT                   /db_xref="PDB:5M1J"
FT                   /db_xref="PDB:5MC6"
FT                   /db_xref="PDB:5NDG"
FT                   /db_xref="PDB:5TGM"
FT                   /db_xref="PDB:5WLC"
FT                   /db_xref="PDB:5WYJ"
FT                   /db_xref="PDB:5WYK"
FT                   /db_xref="PDB:6EML"
FT                   /db_xref="PDB:6FAI"
FT                   /db_xref="PDB:6RBD"
FT                   /db_xref="PDB:6RBE"
FT                   /db_xref="UniProtKB/Swiss-Prot:P06367"
FT                   /experiment="EXISTENCE:direct assay:GO:0003729 mRNA binding
FT                   [PMID:9858605]"
FT                   /experiment="EXISTENCE:direct assay:GO:0030686 90S
FT                   preribosome [PMID:12150911]"
FT                   /experiment="EXISTENCE:direct assay:GO:0032040
FT                   small-subunit processome [PMID:15590835]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0000462
FT                   maturation of SSU-rRNA from tricistronic rRNA transcript
FT                   (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:16246728]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000028
FT                   ribosomal small subunit assembly
FT                   [PMID:2277060|PMID:8293976]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000462
FT                   maturation of SSU-rRNA from tricistronic rRNA transcript
FT                   (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:15125836]"
FT                   /protein_id="DAA07510.1"
FT                   /translation="MSNVVQARDNSQVFGVARIYASFNDTFVHVTDLSGKETIARVTGG
FT                   MKVKADRDESSPYAAMLAAQDVAAKCKEVGITAVHVKIRATGGTRTKTPGPGGQAALRA
FT                   LARSGLRIGRIEDVTPVPSDSTRKKGGRRGRRL"
FT   gene            complement(178610..178798)
FT                   /locus_tag="snR189"
FT   ncRNA           complement(178610..178798)
FT                   /locus_tag="snR189"
FT                   /product="SNR189"
FT                   /note="snoRNA gene; H/ACA box small nucleolar RNA (snoRNA);
FT                   guides pseudouridylation of large subunit (LSU) rRNA at
FT                   position U2735 and small subunit (SSU) rRNA at position
FT                   U466"
FT                   /experiment="EXISTENCE:curator inference:GO:0005730
FT                   nucleolus [PMID:15923376]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000454 snoRNA
FT                   guided rRNA pseudouridine synthesis
FT                   [PMID:15306656|PMID:15923376]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0030559 rRNA
FT                   pseudouridylation guide activity
FT                   [PMID:15306656|PMID:15923376]"
FT                   /experiment="EXISTENCE:physical interaction:GO:0031429 box
FT                   H/ACA snoRNP complex [PMID:15923376]"
FT                   /ncRNA_class="other"
FT   gene            179520..186023
FT                   /gene="BPH1"
FT                   /locus_tag="YCR032W"
FT   mRNA            179520..186023
FT                   /gene="BPH1"
FT                   /locus_tag="YCR032W"
FT                   /product="Bph1p"
FT   CDS_pept        179520..186023
FT                   /codon_start=1
FT                   /gene="BPH1"
FT                   /locus_tag="YCR032W"
FT                   /product="Bph1p"
FT                   /note="Protein homologous to Chediak-Higashi syndrome and
FT                   Beige proteins; both of which are implicated in disease
FT                   syndromes in human and mouse, respectively, due to
FT                   defective lysosomal trafficking; mutant phenotype and
FT                   genetic interactions suggest a role in protein sorting"
FT                   /db_xref="GOA:P25356"
FT                   /db_xref="InterPro:IPR000409"
FT                   /db_xref="InterPro:IPR015943"
FT                   /db_xref="InterPro:IPR017986"
FT                   /db_xref="InterPro:IPR023362"
FT                   /db_xref="InterPro:IPR036322"
FT                   /db_xref="InterPro:IPR036372"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25356"
FT                   /experiment="EXISTENCE:direct assay:GO:0000329 fungal-type
FT                   vacuole membrane [PMID:26928762]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005739
FT                   mitochondrion [PMID:14576278|PMID:16823961]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005829 cytosol
FT                   [PMID:15296494]"
FT                   /experiment="EXISTENCE:direct assay:GO:0019898 extrinsic
FT                   component of membrane [PMID:15296494]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006886
FT                   intracellular protein transport [PMID:15296494]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0009268 response
FT                   to pH [PMID:9509574]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0031505
FT                   fungal-type cell wall organization [PMID:15296494]"
FT                   /protein_id="DAA07511.1"
FT                   /translation="MNSIINAASKVLRLQDDVKKATIILGDILILQPINHEVEPDVENL
FT                   VQHELTKIIQGYPIQDNMIINSKKGTVEDDLCELNNYTCFALSKSFDLCHDSRNFNIAQ
FT                   PKRWIQLLETLTDSVSFAVIVQIILTLSNISLINKQTLGKLKKLRIRIFEILSNKNDSW
FT                   KSTLLQKNLIEWYIFMLSVDCTPLELQNLYLHKELKFCNGILNSLTLQVSDPRSQNYLQ
FT                   FENTYKLFQIQKSSRINNSFLFYIEFNSVTSNRIMTIERHIYLEIKEGQFCISNDNYII
FT                   GLFENFEFEAGTLYFIGVLIDHNNRITLYVDGSMINQLTLFENSICQLSTCELGSMICS
FT                   IKVYRFYLWDGLLTEFAINILQAIGTNYQYTFSKKKEGPEVLSLCQDFLIAKAHLMARP
FT                   TTEISSTKYIDEIELLEMENIIIDVNPNDILQDFTESSNFTVKFEESTNSKNIPEVGKC
FT                   YFYRSSNLVSKFVSIDSIRLAFLNMTESGSIDDLFHHVSHLMNLLRNIDILNWFKKDFG
FT                   FPLFAYTLKQKITQDLSQPLNIQFFNLFLEFCGWDFNDISKSIILDTDAYENIVLNLDL
FT                   WYMNEDQSSLASGGLEIIRFLFFQISSLMEASIYSKFNSNKFNDMNILEKLCLSYQAVT
FT                   KRENQNSKFNELSSDLISVFVTLLKSNTDKRHLQWFLHLSYYFIKRKDVRSTEIILQAV
FT                   DQLFSFYLDQGSDENAKILSEIIPLKLILMIMDQIVENNESNPITCLNILFKVVLTNKP
FT                   LFKQFYKNDGLKLILTMLCKVGKSYREEIISLLLTYSIGNYTTANEIFSGAEDMIGGIS
FT                   NDKITAKEIIYLAVNFIEWHVINSNASDSSSVLDLNNHILRFVEDLKSLSAVPINESVF
FT                   DPKKSYVMVSLLDLSIALNESEDISKFKSSSKVISELIKGNIMCALTKYAAYDFEVYMS
FT                   TFFCHSTEYKLVYPKTVMNNSSYLELSFIVTLLPEILNDLVDSNNNLNLMMLKHPYTMS
FT                   NLLYFLRKFRPDTSQIVMPKDFYFSSYTCLLHCVIQIDKSSFYHFKNVSKSQLLQDFKI
FT                   CIMNLIYSNTLKQIIWEKEEYEMFSESLMAHQEVLFAHGACDNETVGLLLIFFANRLRD
FT                   CGYNKAVFNCMKVIIKNKERKLKEVACFFDPANKSEVLEGLSNILSCNNSETMNLITEQ
FT                   YPFFFNNTQQVRFINIVTNILFKNNNFSPISVRQIKNQVYEWKNARSEYVTQNNKKCLI
FT                   LFRKDNTSLDFKIKKSISRYTYNLKTDREENAVFYRNNLNLLIFHLKHTLEIQSNPNSS
FT                   CKWSSDFAEDFDGMKRRLLPAWEPKYEPLINEEDANQDTITGGNRQRRESGSILSYEFI
FT                   EHMETLESEPVGDLNENRKILRLLKDNDSIATIWNCSLIIGLEIKEGILIHGSNYLYFV
FT                   SDYYFSLEDKKILKLSEVSQESRDMTVSLINGPDVKRVSTFLKHEVFVWKLLDITFVTK
FT                   RPFLLRDVAIELLFKERVSAFFSFYNKRVRDDVLRVLNKIPKHLPADPIFSSVLQEIND
FT                   RGNSIVARNGIGKASIASKFTSVFSANNSLIDGFEISKKWVRGEISNFYYLLSINILAG
FT                   RSFNDLTQYPVFPWVIADYESNVLDLENPKTYRDLSKPMGAQSEKRKLQFIERYEALAS
FT                   LENADSAPFHYGTHYSSAMIVSSYLIRLKPFVESFLLLQGGSFGPADRLFSSLERAWSS
FT                   ASSENTTDVRELTPEFFFLPEFLINVNSYDFGTDQSGKKVDDVVLPPWANGDPKVFIQK
FT                   NREALESPYVSAHLHEWIDLIFGYKQKGDIAVKSVNVFNRLSYPGAVNLDNIDDENERR
FT                   AITGIIHNFGQTPLQIFQEPHPEKIACNVQQLTTEVWRKVPMKPIFEKTIFNLNEKNRS
FT                   VDYVIHDPSYFDSLYWRGFAFPNLFFRTEESLVSLRIVHKNWLKIGLDIFKKTHMAQIT
FT                   SFAYWKLGEFITGDKNGLIKVWKYRKDKHSVSGNLENKKTMFGHLCELKEMRCYHDYNT
FT                   LLTLDISGLVYVWDMINFELVRQITNDAQKVAISQHAGSIMVLTKNNAISIFNLNGQIY
FT                   TSKKFEPAKIVSSIDFFDFTKLDAGYRKHIYWKEMEILLVGFEDGTIEIYELFLNFHNE
FT                   WAIKLLKQLCTEKGKAITSIKGQGKTYLSQKRRKDTAEPHEIEVIAGTLDGRLAIWY"
FT   gene            186489..190169
FT                   /gene="SNT1"
FT                   /locus_tag="YCR033W"
FT   mRNA            186489..190169
FT                   /gene="SNT1"
FT                   /locus_tag="YCR033W"
FT                   /product="Snt1p"
FT   CDS_pept        186489..190169
FT                   /codon_start=1
FT                   /gene="SNT1"
FT                   /locus_tag="YCR033W"
FT                   /product="Snt1p"
FT                   /note="Subunit of the Set3C deacetylase complex; interacts
FT                   directly with the Set3C subunit, Sif2p; putative
FT                   DNA-binding protein; mutant has increased aneuploidy
FT                   tolerance; relocalizes to the cytosol in response to
FT                   hypoxia"
FT                   /db_xref="GOA:P25357"
FT                   /db_xref="InterPro:IPR001005"
FT                   /db_xref="InterPro:IPR009057"
FT                   /db_xref="InterPro:IPR017884"
FT                   /db_xref="InterPro:IPR017930"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25357"
FT                   /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
FT                   [PMID:22932476]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005829 cytosol
FT                   [PMID:22932476]"
FT                   /experiment="EXISTENCE:direct assay:GO:0016575 histone
FT                   deacetylation [PMID:11711434]"
FT                   /experiment="EXISTENCE:direct assay:GO:0034967 Set3 complex
FT                   [PMID:11711434]"
FT                   /experiment="EXISTENCE:direct assay:GO:0070210
FT                   Rpd3L-Expanded complex [PMID:19040720]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006355
FT                   regulation of transcription, DNA-templated [PMID:19379692]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0032874 positive
FT                   regulation of stress-activated MAPK cascade
FT                   [PMID:18487345]"
FT                   /protein_id="DAA07512.1"
FT                   /translation="MGYPPPTRRLGDKKRYHYSNNPNRRHPSAVYSKNSFPKSSNNGFV
FT                   SSPTADNSTNPSVTPSTASVPLPTAAPGSTFGIEAPRPSRYDPSSVSRPSSSSYSSTRK
FT                   IGSRYNPDVERSSSTTSSTPESMNTSTITHTNTDIGNSRYSRKTMSRYNPQSTSSTNVT
FT                   HFPSALSNAPPFYVANGSSRRPRSMDDYSPDVTNKLETNNVSSVNNNSPHSYYSRSNKW
FT                   RSIGTPSRPPFDNHVGNMTTTSNTNSIHQREPFWKANSTTILKSTHSQSSPSLHTKKFH
FT                   DANKLDKPEASVKVETPSKDETKAISYHDNNFPPRKSVSKPNAPLEPDNIKVGEEDALG
FT                   KKEVHKSGREIAKEHPTPVKMKEHDELEARAKKVSKINIDGKQDEIWTTAKTVASAVEV
FT                   SKESQKELTRSVERKESPEIRDYERAYDPKALKTDVTKLTVDNDNKSYEEPLEKVEGCI
FT                   FPLPKAETRLWELKNQKRNKIISEQKYLLKKAIRNFSEYPFYAQNKLIHQQATGLILTK
FT                   IISKIKKEEHLKKINLKHDYFDLQKKYEKECEILTKLSENLRKEEIENKRKEHELMEQK
FT                   RREEGIETEKEKSLRHPSSSSSSRRRNRADFVDDAEMENVLLQIDPNYKHYQAAATIPP
FT                   LILDPIRKHSYKFCDVNNLVTDKKLWASRILKDASDNFTDHEHSLFLEGYLIHPKKFGK
FT                   ISHYMGGLRSPEECVLHYYRTKKTVNYKQLLIDKNKKRKMSAAAKRRKRKERSNDEEVE
FT                   VDESKEESTNTIEKEEKSENNAEENVQPVLVQGSEVKGDPLGTPEKVENMIEQRGEEFA
FT                   GELENAERVNDLKRAHDEVGEESNKSSVIETNNGVQIMDPKGAVQNGYYPEETKELDFS
FT                   LENALQRKKHKSAPEHKTSYWSVRESQLFPELLKEFGSQWSLISEKLGTKSTTMVRNYY
FT                   QRNAARNGWKLLVDETDLKRDGTSSESVQQSQILIQPERPNINAYSNIPPQQRPALGYF
FT                   VGQPTHGHNTSISSIDGSIRPFGPDFHRDTFSKISAPLTTLPPPRLPSIQFPRSEMAEP
FT                   TVTDLRNRPLDHIDTLADAASSVTNNQNFSNERNAIDIGRKSTTISNLLNNSDRSMKSS
FT                   FQSASRHEAQLEDTPSMNNIVVQEIKPNITTPRSSSISALLNPVNGNGQSNPDGRPLLP
FT                   FQHAISQGTPTFPLPAPRTSPISRAPPKFNFSNDPLAALAAVASAPDAMSSFLSKKENN
FT                   N"
FT   gene            190592..191635
FT                   /gene="ELO2"
FT                   /gene_synonym="FEN1"
FT                   /gene_synonym="GNS1"
FT                   /gene_synonym="VBM2"
FT                   /locus_tag="YCR034W"
FT   mRNA            190592..191635
FT                   /gene="ELO2"
FT                   /gene_synonym="FEN1"
FT                   /gene_synonym="GNS1"
FT                   /gene_synonym="VBM2"
FT                   /locus_tag="YCR034W"
FT                   /product="fatty acid elongase ELO2"
FT   CDS_pept        190592..191635
FT                   /codon_start=1
FT                   /gene="ELO2"
FT                   /gene_synonym="GNS1"
FT                   /gene_synonym="VBM2"
FT                   /gene_synonym="FEN1"
FT                   /locus_tag="YCR034W"
FT                   /product="fatty acid elongase ELO2"
FT                   /EC_number="2.3.1.199"
FT                   /note="Fatty acid elongase, involved in sphingolipid
FT                   biosynthesis; acts on fatty acids of up to 24 carbons in
FT                   length; mutations have regulatory effects on
FT                   1,3-beta-glucan synthase, vacuolar ATPase, and the
FT                   secretory pathway; ELO2 has a paralog, ELO1, that arose
FT                   from the whole genome duplication; lethality of the elo2
FT                   elo3 double null mutation is functionally complemented by
FT                   human ELOVL1 and weakly complemented by human ELOVL3 or
FT                   ELOV7"
FT                   /db_xref="GOA:P25358"
FT                   /db_xref="InterPro:IPR002076"
FT                   /db_xref="InterPro:IPR030457"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25358"
FT                   /experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
FT                   reticulum [PMID:12087109]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0032511 late
FT                   endosome to vacuole transport via multivesicular body
FT                   sorting pathway [PMID:23325927]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0009922 fatty
FT                   acid elongase activity [PMID:12684876]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0016192
FT                   vesicle-mediated transport [PMID:9832547]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0030148
FT                   sphingolipid biosynthetic process [PMID:9211877]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0030497 fatty
FT                   acid elongation [PMID:9211877]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0042761 very
FT                   long-chain fatty acid biosynthetic process [PMID:23325927]"
FT                   /protein_id="DAA07513.1"
FT                   /translation="MNSLVTQYAAPLFERYPQLHDYLPTLERPFFNISLWEHFDDVVTR
FT                   VTNGRFVPSEFQFIAGELPLSTLPPVLYAITAYYVIIFGGRFLLSKSKPFKLNGLFQLH
FT                   NLVLTSLSLTLLLLMVEQLVPIIVQHGLYFAICNIGAWTQPLVTLYYMNYIVKFIEFID
FT                   TFFLVLKHKKLTFLHTYHHGATALLCYTQLMGTTSISWVPISLNLGVHVVMYWYYFLAA
FT                   RGIRVWWKEWVTRFQIIQFVLDIGFIYFAVYQKAVHLYFPILPHCGDCVGSTTATFAGC
FT                   AIISSYLVLFISFYINVYKRKGTKTSRVVKRAHGGVAAKVNEYVNVDLKNVPTPSPSPK
FT                   PQHRRKR"
FT   gene            complement(191834..193018)
FT                   /gene="RRP43"
FT                   /locus_tag="YCR035C"
FT   mRNA            complement(191834..193018)
FT                   /gene="RRP43"
FT                   /locus_tag="YCR035C"
FT                   /product="exosome non-catalytic core subunit RRP43"
FT   CDS_pept        complement(191834..193018)
FT                   /codon_start=1
FT                   /gene="RRP43"
FT                   /locus_tag="YCR035C"
FT                   /product="exosome non-catalytic core subunit RRP43"
FT                   /note="Exosome non-catalytic core component; involved in
FT                   3'-5' RNA processing and degradation in both the nucleus
FT                   and the cytoplasm; has similarity to E. coli RNase PH and
FT                   to human hRrp43p (OIP2, EXOSC8); protein abundance
FT                   increases in response to DNA replication stress"
FT                   /db_xref="GOA:P25359"
FT                   /db_xref="InterPro:IPR001247"
FT                   /db_xref="InterPro:IPR020568"
FT                   /db_xref="InterPro:IPR027408"
FT                   /db_xref="InterPro:IPR033196"
FT                   /db_xref="PDB:4IFD"
FT                   /db_xref="PDB:4OO1"
FT                   /db_xref="PDB:5C0W"
FT                   /db_xref="PDB:5C0X"
FT                   /db_xref="PDB:5G06"
FT                   /db_xref="PDB:5JEA"
FT                   /db_xref="PDB:5K36"
FT                   /db_xref="PDB:5OKZ"
FT                   /db_xref="PDB:5VZJ"
FT                   /db_xref="PDB:6FSZ"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25359"
FT                   /experiment="EXISTENCE:curator inference:GO:0043628 ncRNA
FT                   3'-end processing [PMID:10465791]"
FT                   /experiment="EXISTENCE:curator inference:GO:0070478
FT                   nuclear-transcribed mRNA catabolic process, 3'-5'
FT                   exonucleolytic nonsense-mediated decay [PMID:10465791]"
FT                   /experiment="EXISTENCE:curator inference:GO:0070481
FT                   nuclear-transcribed mRNA catabolic process, non-stop decay
FT                   [PMID:10465791]"
FT                   /experiment="EXISTENCE:curator inference:GO:0070651
FT                   nonfunctional rRNA decay [PMID:10465791]"
FT                   /experiment="EXISTENCE:curator inference:GO:0071051
FT                   polyadenylation-dependent snoRNA 3'-end processing
FT                   [PMID:10465791]"
FT                   /experiment="EXISTENCE:direct assay:GO:0000176 nuclear
FT                   exosome (RNase complex) [PMID:10465791|PMID:19046973]"
FT                   /experiment="EXISTENCE:direct assay:GO:0000177 cytoplasmic
FT                   exosome (RNase complex) [PMID:10465791|PMID:19046973]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005654 nucleoplasm
FT                   [PMID:9891085]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005730 nucleolus
FT                   [PMID:9891085]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
FT                   [PMID:9891085]"
FT                   /experiment="EXISTENCE:direct assay:GO:0071038 nuclear
FT                   polyadenylation-dependent tRNA catabolic process
FT                   [PMID:15828860|PMID:17643380]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000467
FT                   exonucleolytic trimming to generate mature 3'-end of 5.8S
FT                   rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S
FT                   rRNA, LSU-rRNA) [PMID:10508172|PMID:12364597|PMID:9390555]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006397 mRNA
FT                   processing [PMID:27385342]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0034427
FT                   nuclear-transcribed mRNA catabolic process, exonucleolytic,
FT                   3'-5' [PMID:12364597]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0071035 nuclear
FT                   polyadenylation-dependent rRNA catabolic process
FT                   [PMID:18940861]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0071042 nuclear
FT                   polyadenylation-dependent mRNA catabolic process
FT                   [PMID:19369424]"
FT                   /protein_id="DAA07514.1"
FT                   /translation="MAESTTLETIEIHPITFPPEVLARISPELSLQRHLSLGIRPCLRK
FT                   YEEFRDVAIENNTLSRYADAGNIDTKNNILGSNVLKSGKTIVITSITGGIIEETSAAIK
FT                   DLDDFGEEELFEVTKEEDIIANYASVYPVVEVERGRVGACTDEEMTISQKLHDSILHSR
FT                   ILPKKALKVKAGVRSANEDGTFSVLYPDELEDDTLNETNLKMKRKWSYVLYAKIVVLSR
FT                   TGPVFDLCWNSLMYALQSVKLPRAFIDERASDLRMTIRTRGRSATIRETYEIICDQTKS
FT                   VPLMINAKNIAFASNYGIVELDPECQLQNSDNSEEEEVDIDMDKLNTVLIADLDTEAEE
FT                   TSIHSTISILAAPSGNYKQLTLVGGGAKITPEMIKRSLLLSRVRADDLSTRFNI"
FT   gene            193297..194298
FT                   /gene="RBK1"
FT                   /locus_tag="YCR036W"
FT   mRNA            193297..194298
FT                   /gene="RBK1"
FT                   /locus_tag="YCR036W"
FT                   /product="putative ribokinase"
FT   CDS_pept        193297..194298
FT                   /codon_start=1
FT                   /gene="RBK1"
FT                   /locus_tag="YCR036W"
FT                   /product="putative ribokinase"
FT                   /EC_number="2.7.1.15"
FT                   /note="Putative ribokinase"
FT                   /db_xref="GOA:P25332"
FT                   /db_xref="InterPro:IPR002139"
FT                   /db_xref="InterPro:IPR002173"
FT                   /db_xref="InterPro:IPR011611"
FT                   /db_xref="InterPro:IPR011877"
FT                   /db_xref="InterPro:IPR029056"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25332"
FT                   /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
FT                   [PMID:14562095]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
FT                   [PMID:14562095]"
FT                   /protein_id="DAA07515.1"
FT                   /translation="MGITVIGSLNYDLDTFTDRLPNAGETFRANHFETHAGGKGLNQAA
FT                   AIGKLKNPSSRYSVRMIGNVGNDTFGKQLKDTLSDCGVDITHVGTYEGINTGTATILIE
FT                   EKAGGQNRILIVEGANSKTIYDPKQLCEIFPEGKEEEEYVVFQHEIPDPLSIIKWIHAN
FT                   RPNFQIVYNPSPFKAMPKKDWELVDLLVVNEIEGLQIVESVFDNELVEEIREKIKDDFL
FT                   GEYRKICELLYEKLMNRKKRGIVVMTLGSRGVLFCSHESPEVQFLPAIQNVSVVDTTGA
FT                   GDTFLGGLVTQLYQGETLSTAIKFSTLASSLTIQRKGAAESMPLYKDVQKDA"
FT   rep_origin      194308..194367
FT                   /note="ARS313; Autonomously Replicating Sequence on
FT                   Chromosome III"
FT   gene            complement(194414..197185)
FT                   /gene="PHO87"
FT                   /locus_tag="YCR037C"
FT   mRNA            complement(194414..197185)
FT                   /gene="PHO87"
FT                   /locus_tag="YCR037C"
FT                   /product="SPX domain-containing inorganic phosphate
FT                   transporter"
FT   CDS_pept        complement(194414..197185)
FT                   /codon_start=1
FT                   /gene="PHO87"
FT                   /locus_tag="YCR037C"
FT                   /product="SPX domain-containing inorganic phosphate
FT                   transporter"
FT                   /note="Low-affinity inorganic phosphate (Pi) transporter;
FT                   acts upstream of Pho81p in regulation of the PHO pathway;
FT                   expression is independent of Pi concentration and Pho4p
FT                   activity; contains 12 membrane-spanning segments; PHO87 has
FT                   a paralog, PHO90, that arose from the whole genome
FT                   duplication"
FT                   /db_xref="GOA:P25360"
FT                   /db_xref="InterPro:IPR004331"
FT                   /db_xref="InterPro:IPR004680"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25360"
FT                   /experiment="EXISTENCE:direct assay:GO:0005886 plasma
FT                   membrane [PMID:21143198]"
FT                   /experiment="EXISTENCE:direct assay:GO:0071944 cell
FT                   periphery [PMID:26928762]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0005315
FT                   inorganic phosphate transmembrane transporter activity
FT                   [PMID:11779791]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0006817
FT                   phosphate ion transport [PMID:11779791]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:2000185
FT                   regulation of phosphate transmembrane transport
FT                   [PMID:12821119]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006797
FT                   polyphosphate metabolic process [PMID:17804816]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0097080 plasma
FT                   membrane selenite transport [PMID:20688911]"
FT                   /protein_id="DAA07516.1"
FT                   /translation="MRFSHFLKYNAVPEWQNHYLDYNELKNLIYTLQTDELKQETPTGD
FT                   LNDDADSQTPGPIADIESNIAAGEPSSSKRRFTHKLKRKLFGSKTPSGSKRGDSDEKAI
FT                   DGNNINEETIELDELSPQGKTTSFNKNFIRKKFFESRSSSVSSEGKTLFSSYDTFVTNL
FT                   SDEKLKVDDFYKRMEAKFYERFDHLINDLEKEGIVTRLNETFNPEIQALPPLREIISGT
FT                   SETHSSNNPFEIHSSNIDSELRNRFDYSEEEMDEDDDVDVFADTTDNTALLNYSQFNIK
FT                   SQKKSLLKQTIINLYIDLCQLKSFIELNRMGFSKITKKSDKVLHMNTRQELIESEEFFK
FT                   DTYIFQHETLSSLNSKIAQLIEFYAVLMGQPGNVDSCKQELKSYLHDHIVWERSNTWKD
FT                   MLGLSSQNNDIITIEDEAEKLMQEKLQIEYFKYPLPKPINLKFTKIENLAVPKLFFGKR
FT                   AMKIGFIIIVTGVLLGVKTFNDPVEHRCMALVECCAFLWASEAIPLHITGLLVPLLTVL
FT                   FRVLKDDDGKVMGAAAASTEILGTMWSSTIMILLAGFTLGEALSQYNVAKVLASWLLAL
FT                   AGTKPRNVLLMAMSVVFFLSMWISNVASPVLTYSLLTPLLDPLDYTSPFAKALVMGVAL
FT                   SADIGGMASPISSPQNIISMQYLKPYGIGWGQFFAVALPTGILSMLCSWALMILTFKIG
FT                   KTKLEKFKPIRTRFTIKQYFIIIVTIATILLWCVESQIESAFGSSGEIAVIPIVLFFGT
FT                   GLLSTKDFNTFPWSIVVLAMGGIALGKAVSSSGLLVTIARALQKKIQNDGVFAILCIFG
FT                   ILMLVVGTFVSHTVSAIIIIPLVQEVGDKLSDPKAAPILVFGCALLASCGMGLASSGFP
FT                   NVTAISMTDKKGNRWLTVGAFISRGVPASLLAFVCVITLGYGISSSVLKGST"
FT   rep_origin      197460..197598
FT                   /note="ARS314; Autonomously Replicating Sequence on
FT                   Chromosome III; active in <10% of cell cycles"
FT   gene            complement(197621..199549)
FT                   /gene="BUD5"
FT                   /locus_tag="YCR038C"
FT   mRNA            complement(197621..199549)
FT                   /gene="BUD5"
FT                   /locus_tag="YCR038C"
FT                   /product="Ras family guanine nucleotide exchange factor
FT                   BUD5"
FT   CDS_pept        complement(197621..199549)
FT                   /codon_start=1
FT                   /gene="BUD5"
FT                   /locus_tag="YCR038C"
FT                   /product="Ras family guanine nucleotide exchange factor
FT                   BUD5"
FT                   /note="GTP/GDP exchange factor for Rsr1p (Bud1p); required
FT                   for both axial and bipolar budding patterns; mutants
FT                   exhibit random budding in all cell types"
FT                   /db_xref="GOA:P25300"
FT                   /db_xref="InterPro:IPR000651"
FT                   /db_xref="InterPro:IPR001895"
FT                   /db_xref="InterPro:IPR008937"
FT                   /db_xref="InterPro:IPR019804"
FT                   /db_xref="InterPro:IPR023578"
FT                   /db_xref="InterPro:IPR036964"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25300"
FT                   /experiment="EXISTENCE:direct assay:GO:0000131 incipient
FT                   cellular bud site [PMID:11313501]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005935 cellular bud
FT                   neck [PMID:11313501]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0005088 Ras
FT                   guanyl-nucleotide exchange factor activity
FT                   [PMID:11589573|PMID:8234337]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0007120 axial
FT                   cellular bud site selection [PMID:1905981]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0007121 bipolar
FT                   cellular bud site selection [PMID:1905981]"
FT                   /protein_id="DAA07517.1"
FT                   /translation="MSPKNKYVYICVEYIYIYFAKIHKQSTLSSDTTKMFVLIDNVLAY
FT                   LLEQDDLFVTARFAIQGQIVSRRVNKIHISNITDVLLQQFISHTLPYNDNIVPKKILDS
FT                   MRTAVRQLLEATACVSRECPLVKRSQDIKRARKRLLSDWYRLGADANMDAVLLVVNSAW
FT                   RFLAVWRPFVNSIQHATQELYQNIAHYLLHGNVNIQRVTALIQLVMGQDDLLFSMDDVL
FT                   QEVFRIQLYLNKMLPHNSHKWQKPSPFDSANLLLNFRDWTTDNALLQELLLSYPTINKN
FT                   KHKNHSVPRLIQIWVESYWQDSETTLKDILNFWYSHLAEYYEYQELFADIVQLFINKKR
FT                   TRQLKIHYIGLTDKEIEENKPPLDYENLFLQYEIDKTNANDELCGATDLSDLLFQWKQG
FT                   ELLEVEAFALNVSPWSLAKTLTLLESSLYLDIETIEFTRHFKHNDTTIDSVFTLSNQLS
FT                   SYVLETTLQQTHTISYWLQVALSCLYLRNLNSLASIITSLQNHSIERLSLPIDVKSDHL
FT                   FQRLKVVVHPNNNYNVYRRTIKHIFHSQLPCVPFTSLLIRDITFIRDGNDTFTKDGNNV
FT                   NMQKFNQITKIVAFAQYLQQKQYEDIHCSNTTARSLLGAMIKVHTLYNDNKDRAYQVSI
FT                   AKVPRLT"
FT   misc_feature    198671..201177
FT                   /note="MATALPHA; Mating type locus; note that the
FT                   systematic sequence in SGD contains MATalpha sequences"
FT   gene            complement(199546..200178)
FT                   /gene="MATALPHA2"
FT                   /gene_synonym="ALPHA2"
FT                   /locus_tag="YCR039C"
FT   mRNA            complement(199546..200178)
FT                   /gene="MATALPHA2"
FT                   /gene_synonym="ALPHA2"
FT                   /locus_tag="YCR039C"
FT                   /product="homeodomain mating type protein alpha2"
FT   CDS_pept        complement(199546..200178)
FT                   /codon_start=1
FT                   /gene="MATALPHA2"
FT                   /gene_synonym="ALPHA2"
FT                   /locus_tag="YCR039C"
FT                   /product="homeodomain mating type protein alpha2"
FT                   /note="Homeobox-domain protein; with Mcm1p, represses
FT                   a-specific genes in haploids; acts with A1p to repress
FT                   transcription of haploid-specific genes in diploids; one of
FT                   two genes encoded by the MATalpha mating type cassette"
FT                   /db_xref="GOA:P0CY08"
FT                   /db_xref="InterPro:IPR001356"
FT                   /db_xref="InterPro:IPR009057"
FT                   /db_xref="PDB:1AKH"
FT                   /db_xref="PDB:1APL"
FT                   /db_xref="PDB:1K61"
FT                   /db_xref="PDB:1LE8"
FT                   /db_xref="PDB:1MNM"
FT                   /db_xref="PDB:1YRN"
FT                   /db_xref="UniProtKB/Swiss-Prot:P0CY08"
FT                   /experiment="EXISTENCE:direct assay:GO:0001198 negative
FT                   regulation of mating-type specific transcription from RNA
FT                   polymerase II promoter [PMID:3893743]"
FT                   /experiment="EXISTENCE:direct assay:GO:0001227 DNA-binding
FT                   transcription repressor activity, RNA polymerase
FT                   II-specific [PMID:15598821]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
FT                   [PMID:1976249]"
FT                   /experiment="EXISTENCE:direct assay:GO:0008301 DNA binding,
FT                   bending [PMID:7569974|PMID:7739902]"
FT                   /experiment="EXISTENCE:direct assay:GO:0043565
FT                   sequence-specific DNA binding [PMID:3893743]"
FT                   /protein_id="DAA07518.1"
FT                   /translation="MNKIPIKDLLNPQITDEFKSSILDINKKLFSICCNLPKLPESVTT
FT                   EEEVELRDILGFLSRANKNRKISDEEKKLLQTTSQLTTTITVLLKEMRSIENDRSNYQL
FT                   TQKNKSADGLVFNVVTQDMINKSTKPYRGHRFTKENVRILESWFAKNIENPYLDTKGLE
FT                   NLMKNTSLSRIQIKNWVSNRRRKEKTITIAPELADLLSGEPLAKKKE"
FT   gene            200442..200969
FT                   /gene="MATALPHA1"
FT                   /gene_synonym="ALPHA1"
FT                   /locus_tag="YCR040W"
FT   mRNA            200442..200969
FT                   /gene="MATALPHA1"
FT                   /gene_synonym="ALPHA1"
FT                   /locus_tag="YCR040W"
FT                   /product="transcriptional co-activator mating type protein
FT                   alpha"
FT   CDS_pept        200442..200969
FT                   /codon_start=1
FT                   /gene="MATALPHA1"
FT                   /gene_synonym="ALPHA1"
FT                   /locus_tag="YCR040W"
FT                   /product="transcriptional co-activator mating type protein
FT                   alpha"
FT                   /note="Transcriptional co-activator that regulates
FT                   mating-type-specific genes; targets the transcription
FT                   factor Mcm1p to the promoters of alpha-specific genes; one
FT                   of two genes encoded by the MATalpha mating type cassette"
FT                   /db_xref="GOA:P0CY06"
FT                   /db_xref="InterPro:IPR006856"
FT                   /db_xref="UniProtKB/Swiss-Prot:P0CY06"
FT                   /experiment="EXISTENCE:curator inference:GO:0005634 nucleus
FT                   [PMID:6337727]"
FT                   /experiment="EXISTENCE:direct assay:GO:0008301 DNA binding,
FT                   bending [PMID:15118075]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0003713
FT                   transcription coactivator activity [PMID:6337727]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006357
FT                   regulation of transcription by RNA polymerase II
FT                   [PMID:6337727]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0007532
FT                   regulation of mating-type specific transcription,
FT                   DNA-templated [PMID:6337727]"
FT                   /protein_id="DAA07422.1"
FT                   /translation="MFTSKPAFKIKNKASKSYRNTAVSKKLKEKRLAEHVRPSCFNIIR
FT                   PLKKDIQIPVPSSRFLNKIQIHRIASGSQNTQFRQFNKTSIKSSKKYLNSFMAFRAYYS
FT                   QFGSGVKQNVLSSLLAEEWHADKMQHGIWDYFAQQYNFINPGFGFVEWLTNNYAEVRGD
FT                   GYWEDVFVHLAL"
FT   gene            200911..201243
FT                   /locus_tag="YCR041W"
FT   mRNA            200911..201243
FT                   /locus_tag="YCR041W"
FT                   /product="hypothetical protein"
FT   CDS_pept        200911..201243
FT                   /codon_start=1
FT                   /locus_tag="YCR041W"
FT                   /product="hypothetical protein"
FT                   /note="hypothetical protein; overexpression suppresses the
FT                   high-frequency loss of mini-chromosomes, probably by
FT                   increasing the rate of proper chromosome segregation;
FT                   translated gene product of YCR041W, but not its transcript,
FT                   is responsible for suppression; suppression ability of
FT                   YCR041W is completely dependent on silencing protein Sir4p"
FT                   /db_xref="GOA:P37265"
FT                   /db_xref="UniProtKB/Swiss-Prot:P37265"
FT                   /protein_id="DAA64811.1"
FT                   /translation="MLKYVVTDIGKMCLYIWPYRVWSWRRLFIFRVLNVVSIAILFETP
FT                   HRLALVPNVCLYTHMAIPLSTCLFCLCLCICIKYDITQTQANNQFLASFFVLILTINDL
FT                   DVTFVI"
FT   gene            complement(201174..205397)
FT                   /gene="TAF2"
FT                   /gene_synonym="TAF150"
FT                   /gene_synonym="TSM1"
FT                   /locus_tag="YCR042C"
FT   mRNA            complement(201174..205397)
FT                   /gene="TAF2"
FT                   /gene_synonym="TAF150"
FT                   /gene_synonym="TSM1"
FT                   /locus_tag="YCR042C"
FT                   /product="Taf2p"
FT   CDS_pept        complement(201174..205397)
FT                   /codon_start=1
FT                   /gene="TAF2"
FT                   /gene_synonym="TAF150"
FT                   /gene_synonym="TSM1"
FT                   /locus_tag="YCR042C"
FT                   /product="Taf2p"
FT                   /note="TFIID subunit (150 kDa); involved in RNA polymerase
FT                   II transcription initiation"
FT                   /db_xref="GOA:P23255"
FT                   /db_xref="InterPro:IPR037813"
FT                   /db_xref="UniProtKB/Swiss-Prot:P23255"
FT                   /experiment="EXISTENCE:curator inference:GO:0016251 RNA
FT                   polymerase II general transcription initiation factor
FT                   activity [PMID:15448131]"
FT                   /experiment="EXISTENCE:curator inference:GO:0051123 RNA
FT                   polymerase II preinitiation complex assembly
FT                   [PMID:10788514]"
FT                   /experiment="EXISTENCE:direct assay:GO:0003682 chromatin
FT                   binding [PMID:10818000|PMID:12600943]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005669
FT                   transcription factor TFIID complex
FT                   [PMID:10788514|PMID:15448131]"
FT                   /experiment="EXISTENCE:direct assay:GO:0006366
FT                   transcription by RNA polymerase II
FT                   [PMID:12138208|PMID:15448131]"
FT                   /protein_id="DAA07520.1"
FT                   /translation="MMSFSKNATPRAIVSESSTLHEMKFRNFRVAHEKISLDIDLATHC
FT                   ITGSATIIIIPLIQNLEYVTFDCKEMTIKDVLVENRRCDQFIHDDPLQTNLNGLTSQNV
FT                   LYSDNSIEQSHFLRSKFASLNEYPETDSKSQLTIKIPSSIKISLEDANALSNYTPITPS
FT                   IKTTPGFQESVFTPITLQIEYEIRNPKSGIKFDTVYADKPWLWNVYTSNGEICSSASYW
FT                   VPCVDLLDEKSTWELEFSVPRLVKNIGTSKLIGQNGEESEKEKEDTPEHDEEEEGKPAR
FT                   VIKDEDKDSNLKNDEEGKNSKSKDAQDNDEEEEEGESDEEEEEGEEERRNIEESNNPSL
FT                   RDVIVCCSEYSNIKELPHPIDLTKKKCIFQIINPVAPHHIGWAIGAFNSWSLPLISPPS
FT                   VDAEDEVEEDKLRENVVDNVNDTMDDDIGSDIIPIQIFTLPTQETDELTVINSTVVCQK
FT                   IIDFYSKEFGSYPFTCYSMVFLPTAPSKHMDFAALGICNTRLLYPLEVIDKAFSTTNEL
FT                   AWALANQWSCVNITPLDMNDYWCCLGIAGYMVFQVTKKLMGNNTYKYQLKRNSEAIVEQ
FT                   DFEKPPIGSTFTGSSRPISWSSKDLSFIQLKAPMILHILDRRMTKTERSFGMSRVLPKI
FT                   FLQAMSGDLPNNSLTSSHFQHVCERVNKSKLENFFNEWVYGSGVPILRVTQRFNRKRMV
FT                   IELGIRQVQDEELGHEKVVGEEGFFKSALDHLEHPDLNRTECFTGSMTIRIHEHDGTPY
FT                   EHIVEIKDTFTKIDIQYNTKYRRLRKRGGGANDENGVENNNEEKPIVVDVNCLGNVYMS
FT                   PEECSRFSLTEFNRTSESNELLKQNEAFEWIRIDSDLEWICQMHINQPDYMFSSQLRQD
FT                   GDIEAQLEAIRYYEDVVVNGGVKSLVYSSILFRTAIDERYFFGIRLAACEALSKYVYDP
FT                   DFTGGVKHLIQIFQILFCLEDSNIPKSNNFENPKLYFLQCNIPKYLAKVKNENGKCPKL
FT                   VKQFLLDILVYNENGENKYSDDAYVRSLIENVVKVALNEYKDKAYMEKVKTQLLRYENL
FT                   VNWLSSYESLIKTTIMYAKYKLHKVGAYDFTELTGMIMHTLTLGINNGDISRESFQNEF
FT                   LMVLKIMLLEGGLKNKDALVLFTEILCFHEDSYIRDKSVDVLSECVNLVVMDGSLDTIS
FT                   DDIKSSVQSVHNEVKNIKSEDDIELFLSGHYVDDMKIKIEKIGRQNISGLIQICRDMFK
FT                   GYSPLKILLWDVLNLPVLSLYQRKQIHDLVRVMYTLINSFVVRLETPRERRLVAKMNSN
FT                   EEGKLDIVIKRESILKVHIKKEVTSTVEAPKKANKIKISLKGDKPVRKVEKQIVKPKVT
FT                   SKQRKVKSHVNRMGSLPLRFVKIQQQPRVMVHLSSVPYSQFVQITKVTSRSFMVKIRTK
FT                   NDAKN"
FT   gene            complement(206261..206644)
FT                   /locus_tag="YCR043C"
FT   mRNA            complement(206261..206644)
FT                   /locus_tag="YCR043C"
FT                   /product="hypothetical protein"
FT   CDS_pept        complement(206261..206644)
FT                   /codon_start=1
FT                   /locus_tag="YCR043C"
FT                   /product="hypothetical protein"
FT                   /note="hypothetical protein; green fluorescent protein
FT                   (GFP)-fusion protein localizes to the Golgi apparatus;
FT                   YCR043C is not an essential gene"
FT                   /db_xref="GOA:P25361"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25361"
FT                   /experiment="EXISTENCE:direct assay:GO:0005794 Golgi
FT                   apparatus [PMID:14562095]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005829 cytosol
FT                   [PMID:26928762]"
FT                   /experiment="EXISTENCE:direct assay:GO:0043332 mating
FT                   projection tip [PMID:19053807]"
FT                   /protein_id="DAA07521.1"
FT                   /translation="MIPAPLDASLLREHAFQGTNDLSTVLSPSTFTDEGGYKPVLKYGL
FT                   GYFNYGLVIDDEVYDYSVCDIIRGHVYDHFWCYFCCFMILFTIWLISLNWCPSSKKSKF
FT                   DWSKKKDDFKMEGGDLEYQHVKI"
FT   gene            complement(206877..207950)
FT                   /gene="PER1"
FT                   /gene_synonym="COS16"
FT                   /locus_tag="YCR044C"
FT   mRNA            complement(206877..207950)
FT                   /gene="PER1"
FT                   /gene_synonym="COS16"
FT                   /locus_tag="YCR044C"
FT                   /product="Per1p"
FT   CDS_pept        complement(206877..207950)
FT                   /codon_start=1
FT                   /gene="PER1"
FT                   /gene_synonym="COS16"
FT                   /locus_tag="YCR044C"
FT                   /product="Per1p"
FT                   /note="Protein of the endoplasmic reticulum; required for
FT                   GPI-phospholipase A2 activity that remodels the GPI anchor
FT                   as a prerequisite for association of GPI-anchored proteins
FT                   with lipid rafts; functionally complemented by human
FT                   ortholog PERLD1"
FT                   /db_xref="GOA:P25625"
FT                   /db_xref="InterPro:IPR007217"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25625"
FT                   /experiment="EXISTENCE:direct assay:GO:0000329 fungal-type
FT                   vacuole membrane [PMID:9560393]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
FT                   reticulum [PMID:17021251]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006506 GPI
FT                   anchor biosynthetic process [PMID:17021251]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0030026 cellular
FT                   manganese ion homeostasis [PMID:9560393]"
FT                   /protein_id="DAA07522.1"
FT                   /translation="MRLAVVVTLLVHCFLVTCSPGDNLDEFIDCTYACEYNRRCPNSQI
FT                   NYIDPETNMFHDIEFFDTPPLYSKLLFWDCISDCDYQCQHIITRWRIDEEEEIYQFHGK
FT                   WPFLRVLGTQEFFSTIFSIGNFIPHYKGFVKFSRIIREEGDRRRKNSRSILIWNYLYVT
FT                   VAGMLAWTASSVFHCRDLIITEKLDYFFAGLTVLTGFHAIFARMTSMFLYPKIAQAFTA
FT                   SVAAIFALHILRLYVDWSYTYNMRFNIFFGVLQYILLIMLSCQNYHALQKQKLMGEFKK
FT                   TAYSSFKRQIFKLCVIPILLVIVTTMAMSLELFDFFSYEWQIDAHALWHLCTIWPSWVL
FT                   YDFFLEDYAYWGNRQLY"
FT   gene            complement(208135..209610)
FT                   /gene="RRT12"
FT                   /gene_synonym="OSW3"
FT                   /locus_tag="YCR045C"
FT   mRNA            complement(208135..209610)
FT                   /gene="RRT12"
FT                   /gene_synonym="OSW3"
FT                   /locus_tag="YCR045C"
FT                   /product="Rrt12p"
FT   CDS_pept        complement(208135..209610)
FT                   /codon_start=1
FT                   /gene="RRT12"
FT                   /gene_synonym="OSW3"
FT                   /locus_tag="YCR045C"
FT                   /product="Rrt12p"
FT                   /note="Probable subtilisin-family protease; role in
FT                   formation of the dityrosine layer of spore walls; localizes
FT                   to the spore wall and also the nuclear envelope and ER
FT                   region in mature spores"
FT                   /db_xref="GOA:P25381"
FT                   /db_xref="InterPro:IPR000209"
FT                   /db_xref="InterPro:IPR015500"
FT                   /db_xref="InterPro:IPR022398"
FT                   /db_xref="InterPro:IPR023827"
FT                   /db_xref="InterPro:IPR023828"
FT                   /db_xref="InterPro:IPR034193"
FT                   /db_xref="InterPro:IPR036852"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25381"
FT                   /experiment="EXISTENCE:direct assay:GO:0005619 ascospore
FT                   wall [PMID:19779569]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005635 nuclear
FT                   envelope [PMID:19779569]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0030476
FT                   ascospore wall assembly [PMID:19779569]"
FT                   /protein_id="DAA07523.1"
FT                   /translation="MKPQCILISLLVNLAYAEEYLVRFKNPTAFQQFTSNSNRSWRQFI
FT                   DNKIEKKFSIGSFRGVTMNLSKNLVNKLKKSPLVADIVPNFRFEAFEGDSVNSAESSYT
FT                   FNATAKYSYEDVEEEQNITYQPDAPRHLARISRHYQLPFDVGDKDRYKSWFNYYYEHDY
FT                   QGQDVNAYIMDTGIFADHPEFEDRVIQGIDLTKEGFGDQNGHGTHVAGLVGSKTYGAAK
FT                   RVNLVEVKVLGKDGSGEASNVLSGLEFIVEHCTKVSRPQGKKCVANLSLGSFRSPIINM
FT                   AVEGAIEEGIVFVAAAGNFNLDAYWASPASAENVITVGAFDDHIDTIAKFSNWGPCVNI
FT                   FAPGVEIESLSHLNYNDTLILSGTSMSTPIVTGVAAILLSKGIEPEMIAQEIEYLSTRN
FT                   VFHRRTLFFKPSTPNQILYNGVDKLDDPYDDETFPRLNIEAIAKELEEYNATLQTPMSE
FT                   NLQSGSKLWGWNNDVTLPLGEIRLKRRDFMKNL"
FT   gene            complement(209914..210423)
FT                   /gene="IMG1"
FT                   /gene_synonym="bL19m"
FT                   /locus_tag="YCR046C"
FT   mRNA            complement(209914..210423)
FT                   /gene="IMG1"
FT                   /gene_synonym="bL19m"
FT                   /locus_tag="YCR046C"
FT                   /product="mitochondrial 54S ribosomal protein IMG1"
FT   CDS_pept        complement(209914..210423)
FT                   /codon_start=1
FT                   /gene="IMG1"
FT                   /gene_synonym="bL19m"
FT                   /locus_tag="YCR046C"
FT                   /product="mitochondrial 54S ribosomal protein IMG1"
FT                   /note="Mitochondrial ribosomal protein of the large
FT                   subunit; required for respiration and for maintenance of
FT                   the mitochondrial genome"
FT                   /db_xref="GOA:P25626"
FT                   /db_xref="InterPro:IPR001857"
FT                   /db_xref="InterPro:IPR008991"
FT                   /db_xref="InterPro:IPR038657"
FT                   /db_xref="PDB:3J6B"
FT                   /db_xref="PDB:5MRC"
FT                   /db_xref="PDB:5MRE"
FT                   /db_xref="PDB:5MRF"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25626"
FT                   /experiment="EXISTENCE:curator inference:GO:0032543
FT                   mitochondrial translation [PMID:12392552]"
FT                   /experiment="EXISTENCE:direct assay:GO:0003735 structural
FT                   constituent of ribosome [PMID:12392552]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005739
FT                   mitochondrion [PMID:16823961|PMID:24769239]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005762
FT                   mitochondrial large ribosomal subunit [PMID:12392552]"
FT                   /protein_id="DAA07524.1"
FT                   /translation="MWSRNVRLLGSWTRSYMVPATKRKTIPVYPPVQRIASSQIMKQVA
FT                   LSEIESLDPGAVKRKLISKKNKDRLKAGDVVRIVYDSSKCSYDTFVGYILSIDRKQLVQ
FT                   DASLLLRNQIAKTAVEIRVPLFSPLIERIDLLTPHVSSRQRNKHYYIRGTRLDVGDLEA
FT                   GLRRKK"
FT   gene            complement(210718..211545)
FT                   /gene="BUD23"
FT                   /locus_tag="YCR047C"
FT   mRNA            complement(210718..211545)
FT                   /gene="BUD23"
FT                   /locus_tag="YCR047C"
FT                   /product="18S rRNA (guanine1575-N7)-methyltransferase"
FT   CDS_pept        complement(210718..211545)
FT                   /codon_start=1
FT                   /gene="BUD23"
FT                   /locus_tag="YCR047C"
FT                   /product="18S rRNA (guanine1575-N7)-methyltransferase"
FT                   /EC_number="2.1.1.309"
FT                   /note="Methyltransferase that methylates residue G1575 of
FT                   18S rRNA; required for rRNA processing and nuclear export
FT                   of 40S ribosomal subunits independently of methylation
FT                   activity; diploid mutant displays random budding pattern;
FT                   functional homolog of human WBSCR22"
FT                   /db_xref="GOA:P25627"
FT                   /db_xref="InterPro:IPR013216"
FT                   /db_xref="InterPro:IPR022238"
FT                   /db_xref="InterPro:IPR029063"
FT                   /db_xref="InterPro:IPR039769"
FT                   /db_xref="PDB:4QTT"
FT                   /db_xref="PDB:4QTU"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25627"
FT                   /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
FT                   [PMID:14562095]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005730 nucleolus
FT                   [PMID:18332120]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
FT                   [PMID:14562095]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000056
FT                   ribosomal small subunit export from nucleus
FT                   [PMID:18332120]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000447
FT                   endonucleolytic cleavage in ITS1 to separate SSU-rRNA from
FT                   5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript
FT                   (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:18332120]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0016435 rRNA
FT                   (guanine) methyltransferase activity [PMID:18332120]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0070476 rRNA
FT                   (guanine-N7)-methylation [PMID:18332120]"
FT                   /protein_id="DAA07525.1"
FT                   /translation="MSRPEELAPPEIFYNDSEAHKYTGSTRVQHIQAKMTLRALELLNL
FT                   QPCSFILDIGCGSGLSGEILTQEGDHVWCGLDISPSMLATGLSRELEGDLMLQDMGTGI
FT                   PFRAGSFDAAISISAIQWLCNADTSYNDPKQRLMRFFNTLYAALKKGGKFVAQFYPKND
FT                   DQVDDILQSAKVAGFSGGLVVDDPESKKNKKYYLVLSSGAPPQGEEQVNLDGVTMDEEN
FT                   VNLKKQLRQRLKGGKDKESAKSFILRKKELMKRRGRKVAKDSKFTGRKRRHRF"
FT   gene            211929..213761
FT                   /gene="ARE1"
FT                   /gene_synonym="SAT2"
FT                   /locus_tag="YCR048W"
FT   mRNA            211929..213761
FT                   /gene="ARE1"
FT                   /gene_synonym="SAT2"
FT                   /locus_tag="YCR048W"
FT                   /product="sterol acyltransferase"
FT   CDS_pept        211929..213761
FT                   /codon_start=1
FT                   /gene="ARE1"
FT                   /gene_synonym="SAT2"
FT                   /locus_tag="YCR048W"
FT                   /product="sterol acyltransferase"
FT                   /EC_number="2.3.1.26"
FT                   /note="Acyl-CoA:sterol acyltransferase; endoplasmic
FT                   reticulum enzyme that contributes the major sterol
FT                   esterification activity in the absence of oxygen; ARE1 has
FT                   a paralog, ARE2, that arose from the whole genome
FT                   duplication"
FT                   /db_xref="GOA:P25628"
FT                   /db_xref="InterPro:IPR004299"
FT                   /db_xref="InterPro:IPR014371"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25628"
FT                   /experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
FT                   reticulum [PMID:10672016|PMID:26928762]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0034737
FT                   ergosterol O-acyltransferase activity [PMID:10672016]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0034738
FT                   lanosterol O-acyltransferase activity [PMID:10672016]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0016125 sterol
FT                   metabolic process [PMID:10672016]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0034738
FT                   lanosterol O-acyltransferase activity [PMID:10672016]"
FT                   /protein_id="DAA07526.1"
FT                   /translation="MTETKDLLQDEEFLKIRRLNSAEANKRHSVTYDNVILPQESMEVS
FT                   PRSSTTSLVEPVESTEGVESTEAERVAGKQEQEEEYPVDAHMQKYLSHLKSKSRSRFHR
FT                   KDASKYVSFFGDVSFDPRPTLLDSAINVPFQTTFKGPVLEKQLKNLQLTKTKTKATVKT
FT                   TVKTTEKTDKADAPPGEKLESNFSGIYVFAWMFLGWIAIRCCTDYYASYGSAWNKLEIV
FT                   QYMTTDLFTIAMLDLAMFLCTFFVVFVHWLVKKRIINWKWTGFVAVSIFELAFIPVTFP
FT                   IYVYYFDFNWVTRIFLFLHSVVFVMKSHSFAFYNGYLWDIKQELEYSSKQLQKYKESLS
FT                   PETREILQKSCDFCLFELNYQTKDNDFPNNISCSNFFMFCLFPVLVYQINYPRTSRIRW
FT                   RYVLEKVCAIIGTIFLMMVTAQFFMHPVAMRCIQFHNTPTFGGWIPATQEWFHLLFDMI
FT                   PGFTVLYMLTFYMIWDALLNCVAELTRFADRYFYGDWWNCVSFEEFSRIWNVPVHKFLL
FT                   RHVYHSSMGALHLSKSQATLFTFFLSAVFHEMAMFAIFRRVRGYLFMFQLSQFVWTALS
FT                   NTKFLRARPQLSNVVFSFGVCSGPSIIMTLYLTL"
FT   gene            complement(213464..213772)
FT                   /locus_tag="YCR050C"
FT   mRNA            complement(213464..213772)
FT                   /locus_tag="YCR050C"
FT                   /product="hypothetical protein"
FT   CDS_pept        complement(213464..213772)
FT                   /codon_start=1
FT                   /locus_tag="YCR050C"
FT                   /product="hypothetical protein"
FT                   /note="Non-essential hypothetical protein; deletion mutant
FT                   is synthetically sick or lethal with alpha-synuclein"
FT                   /db_xref="GOA:P25630"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25630"
FT                   /protein_id="DAA07527.1"
FT                   /translation="MVAVHKVRYNVIMILGPEQTPNEKTTLDNCGLARRNLVLLKAVHT
FT                   NCDSWNMNRYPLTLLKMANMAISWNTALKKKVNNVAWLLLKCNAPMELWYTCLSKNL"
FT   gene            214071..214739
FT                   /locus_tag="YCR051W"
FT   mRNA            214071..214739
FT                   /locus_tag="YCR051W"
FT                   /product="hypothetical protein"
FT   CDS_pept        214071..214739
FT                   /codon_start=1
FT                   /locus_tag="YCR051W"
FT                   /product="hypothetical protein"
FT                   /note="hypothetical protein; green fluorescent protein
FT                   (GFP)-fusion protein localizes to the cytoplasm and
FT                   nucleus; contains ankyrin (Ank) repeats; YCR051W is not an
FT                   essential gene"
FT                   /db_xref="GOA:P25631"
FT                   /db_xref="InterPro:IPR002110"
FT                   /db_xref="InterPro:IPR020683"
FT                   /db_xref="InterPro:IPR036770"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25631"
FT                   /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
FT                   [PMID:14562095]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
FT                   [PMID:14562095]"
FT                   /protein_id="DAA07528.1"
FT                   /translation="MNANIWVAASDGNLDRVEHILRESKGAMTPQSKDINGYTPMHAAA
FT                   AYGHLDLLKKMCNEYNGDINVLDNDGDTPLHHVEDVATARLIVEELGGDFTIRNVEGQT
FT                   PYDSFVENGEDGELIEYMRIKSGVADVHGVDGVQGEGVIDSKLLEEFKDNVRYTLENDP
FT                   EEGADEATLQRRRQLEQIITGDNAEEELERYIRAMVREQMLGQGSMAGSGDEPDSKRRK
FT                   "
FT   gene            214994..216445
FT                   /gene="RSC6"
FT                   /locus_tag="YCR052W"
FT   mRNA            214994..216445
FT                   /gene="RSC6"
FT                   /locus_tag="YCR052W"
FT                   /product="Rsc6p"
FT   CDS_pept        214994..216445
FT                   /codon_start=1
FT                   /gene="RSC6"
FT                   /locus_tag="YCR052W"
FT                   /product="Rsc6p"
FT                   /note="Component of the RSC chromatin remodeling complex;
FT                   essential for mitotic growth; RSC6 has a paralog, SNF12,
FT                   that arose from the whole genome duplication"
FT                   /db_xref="GOA:P25632"
FT                   /db_xref="InterPro:IPR036885"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25632"
FT                   /experiment="EXISTENCE:direct assay:GO:0006337 nucleosome
FT                   disassembly [PMID:16492771]"
FT                   /experiment="EXISTENCE:direct assay:GO:0015616 DNA
FT                   translocase activity
FT                   [PMID:12183366|PMID:16455496|PMID:17188033|PMID:17918861]"
FT                   /experiment="EXISTENCE:direct assay:GO:0016584 nucleosome
FT                   positioning [PMID:21343911]"
FT                   /experiment="EXISTENCE:direct assay:GO:0016586 RSC-type
FT                   complex [PMID:10619019|PMID:12183366]"
FT                   /experiment="EXISTENCE:direct assay:GO:0032968 positive
FT                   regulation of transcription elongation from RNA polymerase
FT                   II promoter [PMID:17081996]"
FT                   /protein_id="DAA07529.1"
FT                   /translation="MVTQTNPVPVTYPTDAYIPTYLPDDKVSNLADLKKLIEMDSRLDL
FT                   YLTRRRLDTSINLPTNTKTKDHPPNKEMLRIYVYNTTESSPRSDSGTPADSGKTTWTLR
FT                   IEGKLLHESANGKHPFSEFLEGVAVDFKRLKPLGMGKKRKRDSSLSLPLNLQQPEYNDQ
FT                   DSTMGDNDNGEDEDSAEAESREEIVDALEWNYDENNVVEFDGIDIKRQGKDNLRCSITI
FT                   QLRGVDGGKVQYSPNLATLIGMQTGSVNDAVYSIYKYILINNLFVTEQTEAQDGSNDAE
FT                   DSSNENNNKNGAGDDDGVEGSTPKDKPELGEVKLDSLLQKVLDTNAAHLPLMNVVQTVN
FT                   KLVSPLPPIILDYTIDLSKDTTYGATTLDVDVSHILHQPQPQPNLQKEEETDAEDTAKL
FT                   REITKLALQLNSSAQKYQFFHELSLHPRETLTHYLWSSKQNELVLQGDQYFNEDAARTS
FT                   DIYSNNNNDRSLMGNISLLYSQGRL"
FT   gene            216697..218241
FT                   /gene="THR4"
FT                   /locus_tag="YCR053W"
FT   mRNA            216697..218241
FT                   /gene="THR4"
FT                   /locus_tag="YCR053W"
FT                   /product="threonine synthase THR4"
FT   CDS_pept        216697..218241
FT                   /codon_start=1
FT                   /gene="THR4"
FT                   /locus_tag="YCR053W"
FT                   /product="threonine synthase THR4"
FT                   /EC_number="4.2.3.1"
FT                   /note="Threonine synthase; conserved protein that catalyzes
FT                   formation of threonine from O-phosphohomoserine; expression
FT                   is regulated by the GCN4-mediated general amino acid
FT                   control pathway"
FT                   /db_xref="GOA:P16120"
FT                   /db_xref="InterPro:IPR000634"
FT                   /db_xref="InterPro:IPR001926"
FT                   /db_xref="InterPro:IPR004450"
FT                   /db_xref="InterPro:IPR029144"
FT                   /db_xref="InterPro:IPR036052"
FT                   /db_xref="InterPro:IPR037158"
FT                   /db_xref="PDB:1KL7"
FT                   /db_xref="UniProtKB/Swiss-Prot:P16120"
FT                   /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
FT                   [PMID:14562095]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
FT                   [PMID:14562095|PMID:24390141]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0004795
FT                   threonine synthase activity [PMID:8082795]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0009088
FT                   threonine biosynthetic process [PMID:8082795]"
FT                   /protein_id="DAA07530.1"
FT                   /translation="MPNASQVYRSTRSSSPKTISFEEAIIQGLATDGGLFIPPTIPQVD
FT                   QATLFNDWSKLSFQDLAFAIMRLYIAQEEIPDADLKDLIKRSYSTFRSDEVTPLVQNVT
FT                   GDKENLHILELFHGPTYAFKDVALQFVGNLFEYFLQRTNANLPEGEKKQITVVGATSGD
FT                   TGSAAIYGLRGKKDVSVFILYPTGRISPIQEEQMTTVPDENVQTLSVTGTFDNCQDIVK
FT                   AIFGDKEFNSKHNVGAVNSINWARILAQMTYYFYSFFQATNGKDSKKVKFVVPSGNFGD
FT                   ILAGYFAKKMGLPIEKLAIATNENDILDRFLKSGLYERSDKVAATLSPAMDILISSNFE
FT                   RLLWYLAREYLANGDDLKAGEIVNNWFQELKTNGKFQVDKSIIEGASKDFTSERVSNEE
FT                   TSETIKKIYESSVNPKHYILDPHTAVGVCATERLIAKDNDKSIQYISLSTAHPAKFADA
FT                   VNNALSGFSNYSFEKDVLPEELKKLSTLKKKLKFIERADVELVKNAIEEELAKMKL"
FT   gene            complement(218376..220067)
FT                   /gene="CTR86"
FT                   /locus_tag="YCR054C"
FT   mRNA            complement(218376..220067)
FT                   /gene="CTR86"
FT                   /locus_tag="YCR054C"
FT                   /product="Ctr86p"
FT   CDS_pept        complement(218376..220067)
FT                   /codon_start=1
FT                   /gene="CTR86"
FT                   /locus_tag="YCR054C"
FT                   /product="Ctr86p"
FT                   /note="Essential hypothetical protein; with orthologs in
FT                   Ashbya gossypii and Candida albicans; similar to human
FT                   ATXN10, mutations in which cause spinocerebellar ataxia
FT                   type 10; codon usage corresponds to that observed for yeast
FT                   genes expressed at low levels; relative distribution to the
FT                   nucleus increases upon DNA replication stress"
FT                   /db_xref="GOA:P25355"
FT                   /db_xref="InterPro:IPR016024"
FT                   /db_xref="InterPro:IPR019156"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25355"
FT                   /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
FT                   [PMID:22842922]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
FT                   [PMID:14562095|PMID:22842922]"
FT                   /protein_id="DAA07531.1"
FT                   /translation="MPMNNFLDEFNLFDSIITMMKNDPCCVEDYEPIVENLNRIFQRTF
FT                   NDEEHRKSMANSQLFWERLRDTLEAMLLPASLNENSSIPYTRTVRGLILMMRNLAAENQ
FT                   EIPQKLLLQNLVIRGFLHATSEYVVDTPLIKHLYIACLTCLFNIQQNYSTVDMTTFPAL
FT                   LQFLQYPYGIKLEDGEEEEHFWLPYLFLFKTYLNNDEFSNEFFRDNDTPQKDYYCVRDR
FT                   IFFDIVTAKFIQDQENSFLIEKGRNYLDDSKLEITSIDLSVLECISKSLTTASFGKYLN
FT                   GLEERQPGKFTTLLQILQLVVTSKEDWNTYELTAIMSWCYPILQRLACKDIPAFFNKSC
FT                   NDYAPSVAIQLHSTLLSCLDIISDLCKFNHVRKFLISYDSVKILVSLLDTFQKNLLRIN
FT                   FLKGNGDTVNEIKITDHEGNKIEDRLLIFNRVNTNESFIRADNFPHCKLVIIEILASLV
FT                   YAHPEIQDQIRELGGLALILSNCVIDDNDPFIKERSIVCLKFLLKNNAKNQEYVKKMEA
FT                   QDVVQDDALSKAGFEISVEKGGKVRLVSKEEDPGNENSEIISIDED"
FT   gene            complement(220457..223228)
FT                   /gene="PWP2"
FT                   /gene_synonym="UTP1"
FT                   /gene_synonym="YCR055C"
FT                   /gene_synonym="YCR058C"
FT                   /locus_tag="YCR057C"
FT   mRNA            complement(220457..223228)
FT                   /gene="PWP2"
FT                   /gene_synonym="UTP1"
FT                   /gene_synonym="YCR055C"
FT                   /gene_synonym="YCR058C"
FT                   /locus_tag="YCR057C"
FT                   /product="snoRNA-binding rRNA-processing protein PWP2"
FT   CDS_pept        complement(220457..223228)
FT                   /codon_start=1
FT                   /gene="PWP2"
FT                   /gene_synonym="UTP1"
FT                   /gene_synonym="YCR055C"
FT                   /gene_synonym="YCR058C"
FT                   /locus_tag="YCR057C"
FT                   /product="snoRNA-binding rRNA-processing protein PWP2"
FT                   /note="Conserved 90S pre-ribosomal component; essential for
FT                   proper endonucleolytic cleavage of the 35 S rRNA precursor
FT                   at A0, A1, and A2 sites; contains eight WD-repeats; PWP2
FT                   deletion leads to defects in cell cycle and bud
FT                   morphogenesis"
FT                   /db_xref="GOA:P25635"
FT                   /db_xref="InterPro:IPR001680"
FT                   /db_xref="InterPro:IPR007148"
FT                   /db_xref="InterPro:IPR011047"
FT                   /db_xref="InterPro:IPR015943"
FT                   /db_xref="InterPro:IPR017986"
FT                   /db_xref="InterPro:IPR019775"
FT                   /db_xref="InterPro:IPR020472"
FT                   /db_xref="InterPro:IPR027145"
FT                   /db_xref="InterPro:IPR036322"
FT                   /db_xref="PDB:5I2T"
FT                   /db_xref="PDB:5WLC"
FT                   /db_xref="PDB:5WYJ"
FT                   /db_xref="PDB:5WYK"
FT                   /db_xref="PDB:6ND4"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25635"
FT                   /experiment="EXISTENCE:direct assay:GO:0003729 mRNA binding
FT                   [PMID:23222640]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005730 nucleolus
FT                   [PMID:12068309|PMID:12150911]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
FT                   [PMID:8804409]"
FT                   /experiment="EXISTENCE:direct assay:GO:0030686 90S
FT                   preribosome [PMID:15231838|PMID:12150911]"
FT                   /experiment="EXISTENCE:direct assay:GO:0032040
FT                   small-subunit processome [PMID:12068309]"
FT                   /experiment="EXISTENCE:direct assay:GO:0034388
FT                   Pwp2p-containing subcomplex of 90S preribosome
FT                   [PMID:15231838|PMID:17515605]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000447
FT                   endonucleolytic cleavage in ITS1 to separate SSU-rRNA from
FT                   5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript
FT                   (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FT                   [PMID:15231838|PMID:15489292|PMID:15590835]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000462
FT                   maturation of SSU-rRNA from tricistronic rRNA transcript
FT                   (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:12068309]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000472
FT                   endonucleolytic cleavage to generate mature 5'-end of
FT                   SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FT                   [PMID:15231838|PMID:15489292|PMID:15590835]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000480
FT                   endonucleolytic cleavage in 5'-ETS of tricistronic rRNA
FT                   transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FT                   [PMID:15231838|PMID:15489292|PMID:15590835]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000920 septum
FT                   digestion after cytokinesis [PMID:8804409]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0030010
FT                   establishment of cell polarity [PMID:8804409]"
FT                   /protein_id="DAA07532.1"
FT                   /translation="MKSDFKFSNLLGTVYRQGNITFSDDGKQLLSPVGNRVSVFDLINN
FT                   KSFTFEYEHRKNIAAIDLNKQGTLLISIDEDGRAILVNFKARNVLHHFNFKEKCSAVKF
FT                   SPDGRLFALASGRFLQIWKTPDVNKDRQFAPFVRHRVHAGHFQDITSLTWSQDSRFILT
FT                   TSKDLSAKIWSVDSEEKNLAATTFNGHRDYVMGAFFSHDQEKIYTVSKDGAVFVWEFTK
FT                   RPSDDDDNESEDDDKQEEVDISKYSWRITKKHFFYANQAKVKCVTFHPATRLLAVGFTS
FT                   GEFRLYDLPDFTLIQQLSMGQNPVNTVSVNQTGEWLAFGSSKLGQLLVYEWQSESYILK
FT                   QQGHFDSTNSLAYSPDGSRVVTASEDGKIKVWDITSGFCLATFEEHTSSVTAVQFAKRG
FT                   QVMFSSSLDGTVRAWDLIRYRNFRTFTGTERIQFNCLAVDPSGEVVCAGSLDNFDIHVW
FT                   SVQTGQLLDALSGHEGPVSCLSFSQENSVLASASWDKTIRIWSIFGRSQQVEPIEVYSD
FT                   VLALSMRPDGKEVAVSTLKGQISIFNIEDAKQVGNIDCRKDIISGRFNQDRFTAKNSER
FT                   SKFFTTIHYSFDGMAIVAGGNNNSICLYDVPNEVLLKRFIVSRNMALNGTLEFLNSKKM
FT                   TEAGSLDLIDDAGENSDLEDRIDNSLPGSQRGGDLSTRKMRPEVRVTSVQFSPTANAFA
FT                   AASTEGLLIYSTNDTILFDPFDLDVDVTPHSTVEALREKQFLNALVMAFRLNEEYLINK
FT                   VYEAIPIKEIPLVASNIPAIYLPRILKFIGDFAIESQHIEFNLIWIKALLSASGGYINE
FT                   HKYLFSTAMRSIQRFIVRVAKEVVNTTTDNKYTYRFLVSTDGSMEDGAADDDEVLLKDD
FT                   ADEDNEENEENDVVMESDDEEGWIGFNGKDNKLPLSNENDSSDEEENEKELP"
FT   gene            complement(223454..224230)
FT                   /gene="YIH1"
FT                   /locus_tag="YCR059C"
FT   mRNA            complement(223454..224230)
FT                   /gene="YIH1"
FT                   /locus_tag="YCR059C"
FT                   /product="Yih1p"
FT   CDS_pept        complement(223454..224230)
FT                   /codon_start=1
FT                   /gene="YIH1"
FT                   /locus_tag="YCR059C"
FT                   /product="Yih1p"
FT                   /note="Negative regulator of eIF2 kinase Gcn2p; competes
FT                   with Gcn2p for binding to Gcn1p; may contribute to
FT                   regulation of translation in response to starvation via
FT                   regulation of Gcn2p; binds to monomeric actin and to
FT                   ribosomes and polyribosomes; ortholog of mammalian IMPACT"
FT                   /db_xref="GOA:P25637"
FT                   /db_xref="InterPro:IPR001498"
FT                   /db_xref="InterPro:IPR006575"
FT                   /db_xref="InterPro:IPR016135"
FT                   /db_xref="InterPro:IPR020568"
FT                   /db_xref="InterPro:IPR020569"
FT                   /db_xref="InterPro:IPR023582"
FT                   /db_xref="InterPro:IPR036956"
FT                   /db_xref="PDB:6BQI"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25637"
FT                   /experiment="EXISTENCE:direct assay:GO:0003785 actin
FT                   monomer binding [PMID:15126500]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
FT                   [PMID:14562095]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
FT                   [PMID:14562095]"
FT                   /experiment="EXISTENCE:direct assay:GO:0043022 ribosome
FT                   binding [PMID:22404850]"
FT                   /experiment="EXISTENCE:direct assay:GO:1905538 polysome
FT                   binding [PMID:22404850]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0001933 negative
FT                   regulation of protein phosphorylation [PMID:15126500]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0004860 protein
FT                   kinase inhibitor activity [PMID:15126500]"
FT                   /protein_id="DAA07533.1"
FT                   /translation="MDDDHEQLVEELEAVEAIYPDLLSKKQEDGSIIVVKVPQHEYMTL
FT                   QISFPTHYPSEEAPNVIEVGVCTSLAKRDLYDTKYLQHLFQEVMDSVFHRGSVCLFDFL
FT                   TELDGVLYVEPEEETEPVQQSDIPTDPFEGWTASDPITDRGSTFMAFAAHVTSEEQAFA
FT                   MLDLLKTDSKMRKANHVMSAWRIKQDGSAATYQDSDDDGETAAGSRMLHLITIMDVWNV
FT                   IVVVARWFGGAHIGPDRFKHINSTAREAVVRAGFDS"
FT   gene            224399..224734
FT                   /gene="TAH1"
FT                   /locus_tag="YCR060W"
FT   mRNA            224399..224734
FT                   /gene="TAH1"
FT                   /locus_tag="YCR060W"
FT                   /product="Tah1p"
FT   CDS_pept        224399..224734
FT                   /codon_start=1
FT                   /gene="TAH1"
FT                   /locus_tag="YCR060W"
FT                   /product="Tah1p"
FT                   /note="Component of conserved R2TP complex
FT                   (Rvb1-Rvb2-Tah1-Pih1); R2TP complex interacts with Hsp90
FT                   (Hsp82p and Hsc82p) to mediate assembly of large protein
FT                   complexes such as box C/D snoRNPs and RNA polymerase II;
FT                   contains a single TPR domain with at least two TPR motifs;
FT                   plays a role in determining prion variants"
FT                   /db_xref="GOA:P25638"
FT                   /db_xref="InterPro:IPR011990"
FT                   /db_xref="InterPro:IPR013026"
FT                   /db_xref="InterPro:IPR019734"
FT                   /db_xref="PDB:2L6J"
FT                   /db_xref="PDB:2LSU"
FT                   /db_xref="PDB:2LSV"
FT                   /db_xref="PDB:2MNJ"
FT                   /db_xref="PDB:4CGQ"
FT                   /db_xref="PDB:4CGU"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25638"
FT                   /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
FT                   [PMID:14562095]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
FT                   [PMID:14562095]"
FT                   /experiment="EXISTENCE:direct assay:GO:0051087 chaperone
FT                   binding [PMID:18412542]"
FT                   /experiment="EXISTENCE:direct assay:GO:0097255 R2TP complex
FT                   [PMID:15766533]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0006457
FT                   protein folding [PMID:15766533]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000492 box C/D
FT                   snoRNP assembly [PMID:18268103]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006457 protein
FT                   folding [PMID:15766533]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0051087
FT                   chaperone binding [PMID:15766533]"
FT                   /experiment="EXISTENCE:physical interaction:GO:0006457
FT                   protein folding [PMID:15766533]"
FT                   /experiment="EXISTENCE:physical interaction:GO:0051087
FT                   chaperone binding [PMID:15766533]"
FT                   /experiment="EXISTENCE:physical interaction:GO:0097255 R2TP
FT                   complex [PMID:18268103]"
FT                   /protein_id="DAA07534.1"
FT                   /translation="MSQFEKQKEQGNSLFKQGLYREAVHCYDQLITAQPQNPVGYSNKA
FT                   MALIKLGEYTQAIQMCQQGLRYTSTAEHVAIRSKLQYRLELAQGAVGSVQIPVVEVDEL
FT                   PEGYDRS"
FT   rep_origin      224816..225061
FT                   /note="ARS315; Highly-active autonomously replicating
FT                   sequence; initiates replication in 90% of cell cycles"
FT   gene            225563..227458
FT                   /gene_synonym="YCR062W"
FT                   /locus_tag="YCR061W"
FT   mRNA            225563..227458
FT                   /gene_synonym="YCR062W"
FT                   /locus_tag="YCR061W"
FT                   /product="hypothetical protein"
FT   CDS_pept        225563..227458
FT                   /codon_start=1
FT                   /gene_synonym="YCR062W"
FT                   /locus_tag="YCR061W"
FT                   /product="hypothetical protein"
FT                   /note="hypothetical protein; green fluorescent protein
FT                   (GFP)-fusion protein localizes to the cytoplasm in a
FT                   punctate pattern; induced by treatment with
FT                   8-methoxypsoralen and UVA irradiation"
FT                   /db_xref="GOA:P25639"
FT                   /db_xref="InterPro:IPR018825"
FT                   /db_xref="InterPro:IPR018827"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25639"
FT                   /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
FT                   [PMID:14562095]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0008361
FT                   regulation of cell size [PMID:12089449]"
FT                   /protein_id="DAA07535.1"
FT                   /translation="MVRFVSILSLFGCAATLVTAHDDMDMDMDMDMDMDMNIDTTTSQS
FT                   IDVSSTASIVPVPHEPKHLHGLPILQSPSLTPAERLYWENYNTTTYFTTQAGNRSALRY
FT                   HIITLLLVAFVLYPVSLALSAARSRWYLPLLFVNLCICISSVMALSVFKNTFPEEDWYA
FT                   HNIYGTTSVLLLVFMLVHFFAAVLSVPVSLASKKEYRPVDTIPLNDLESTPVMVNSARG
FT                   SPSPSSNRDTLFSLSSDTTTATATNNNKRRRAEGEDEGDNTSNHDTLRDEDYDNDDDEI
FT                   ASIEAPPLLPQDIPVFRILFTNTKYQMLAAHLSCVANVVFHMLTYPLFMYIFVDLIIGF
FT                   AVGNLLGKGIRIFNLLAHWIKGGVFFTLGVVSLARYCGFAAKYGWAWNNISFTSQLTQT
FT                   RSSNLLFRFAPAGTFTMEFVESFLIFFYGSTNIFLEHLAGNGGAWTAKDLQHVSIAFMF
FT                   IGTGLCGLLTEYKLNHWRFEHARKRPQTDVVAATPGYSPNPFPAFTIFWTGILMSQHAQ
FT                   SSQFSTTIHTQWGYLLSYGSFFRLLTFLILFLVPNTNSAASKPFTELITSFCLLCGGLV
FT                   FMESTDQSIEAMEYRGFTPMFTFNLSVGFVSLLMAWEMILFIWKDWLIKTRKTSL"
FT   gene            227942..228042
FT                   /gene="SUP61"
FT                   /locus_tag="tS(CGA)C"
FT   tRNA            227942..228042
FT                   /gene="SUP61"
FT                   /locus_tag="tS(CGA)C"
FT                   /product="tRNA-Ser"
FT                   /note="tS(CGA)C; Serine tRNA (tRNA-Ser), predicted by
FT                   tRNAscan-SE analysis; i6A37 modification is catalyzed by
FT                   Mod5p; can mutate to suppress amber or ochre nonsense
FT                   mutations; suppressor mutant alleles are recessive lethal
FT                   and can only be maintained when an additional wild-type
FT                   copy of the gene is present, because SUP61 encodes the only
FT                   tRNA species that can decode UCG codons"
FT                   /experiment="EXISTENCE:curator inference:GO:0005829 cytosol
FT                   [PMID:9023104]"
FT                   /experiment="EXISTENCE:curator inference:GO:0006414
FT                   translational elongation [PMID:9023104]"
FT   gene            228318..228791
FT                   /gene="BUD31"
FT                   /gene_synonym="CWC14"
FT                   /locus_tag="YCR063W"
FT   mRNA            228318..228791
FT                   /gene="BUD31"
FT                   /gene_synonym="CWC14"
FT                   /locus_tag="YCR063W"
FT                   /product="U2 snRNP complex subunit BUD31"
FT   CDS_pept        228318..228791
FT                   /codon_start=1
FT                   /gene="BUD31"
FT                   /gene_synonym="CWC14"
FT                   /locus_tag="YCR063W"
FT                   /product="U2 snRNP complex subunit BUD31"
FT                   /note="Component of the SF3b subcomplex of the U2 snRNP;
FT                   increases efficiency of first and second step pre-mRNA
FT                   splicing; diploid mutants display a random budding pattern
FT                   instead of the wild-type bipolar pattern; facilitates
FT                   passage through G1/S Start, but is not required for G2/M
FT                   transition or exit from mitosis"
FT                   /db_xref="GOA:P25337"
FT                   /db_xref="InterPro:IPR001748"
FT                   /db_xref="InterPro:IPR018230"
FT                   /db_xref="PDB:2MY1"
FT                   /db_xref="PDB:5GM6"
FT                   /db_xref="PDB:5GMK"
FT                   /db_xref="PDB:5LJ3"
FT                   /db_xref="PDB:5LJ5"
FT                   /db_xref="PDB:5LQW"
FT                   /db_xref="PDB:5MPS"
FT                   /db_xref="PDB:5MQ0"
FT                   /db_xref="PDB:5WSG"
FT                   /db_xref="PDB:5Y88"
FT                   /db_xref="PDB:5YLZ"
FT                   /db_xref="PDB:6BK8"
FT                   /db_xref="PDB:6EXN"
FT                   /db_xref="PDB:6J6G"
FT                   /db_xref="PDB:6J6H"
FT                   /db_xref="PDB:6J6N"
FT                   /db_xref="PDB:6J6Q"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25337"
FT                   /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
FT                   [PMID:14562095]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005686 U2 snRNP
FT                   [PMID:16314500]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000282 cellular
FT                   bud site selection [PMID:11452010]"
FT                   /experiment="EXISTENCE:physical interaction:GO:0000398 mRNA
FT                   splicing, via spliceosome [PMID:16314500|PMID:15303280]"
FT                   /protein_id="DAA07536.1"
FT                   /translation="MPRIKTRRSKPAPDGFEKIKPTLTDFEIQLRDAQKDKSSKLAAKS
FT                   NEQLWEIMQLHHQRSRYIYTLYYKRKAISKDLYDWLIKEKYADKLLIAKWRKTGYEKLC
FT                   CLRCIQKNETNNGSTCICRVPRAQLEEEARKKGTQVSFHQCVHCGCRGCASTD"
FT   gene            229310..231004
FT                   /gene="HCM1"
FT                   /locus_tag="YCR065W"
FT   mRNA            229310..231004
FT                   /gene="HCM1"
FT                   /locus_tag="YCR065W"
FT                   /product="Hcm1p"
FT   CDS_pept        229310..231004
FT                   /codon_start=1
FT                   /gene="HCM1"
FT                   /locus_tag="YCR065W"
FT                   /product="Hcm1p"
FT                   /note="Forkhead transcription factor; drives S-phase
FT                   activation of genes involved in chromosome segregation,
FT                   spindle dynamics, budding; also activates genes involved in
FT                   respiration, use of alternative energy sources (like
FT                   proline), NAD synthesis, oxidative stress resistance; key
FT                   factor in early adaptation to nutrient deficiency and
FT                   diauxic shift; suppressor of calmodulin mutants with
FT                   specific SPB assembly defects; ortholog of C. elegans
FT                   lifespan regulator PHA-4"
FT                   /db_xref="GOA:P25364"
FT                   /db_xref="InterPro:IPR001766"
FT                   /db_xref="InterPro:IPR018122"
FT                   /db_xref="InterPro:IPR030456"
FT                   /db_xref="InterPro:IPR036388"
FT                   /db_xref="InterPro:IPR036390"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25364"
FT                   /experiment="EXISTENCE:direct assay:GO:0000790 nuclear
FT                   chromatin [PMID:12464632]"
FT                   /experiment="EXISTENCE:direct assay:GO:0003700 DNA-binding
FT                   transcription factor activity [PMID:16912276]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
FT                   [PMID:19159085|PMID:20847055]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
FT                   [PMID:20847055]"
FT                   /experiment="EXISTENCE:direct assay:GO:0043565
FT                   sequence-specific DNA binding [PMID:19111667]"
FT                   /experiment="EXISTENCE:direct assay:GO:0045944 positive
FT                   regulation of transcription by RNA polymerase II
FT                   [PMID:8441413]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0051300
FT                   spindle pole body organization [PMID:9920414]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0003700
FT                   DNA-binding transcription factor activity [PMID:16912276]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0007005
FT                   mitochondrion organization [PMID:20847055]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0034599 cellular
FT                   response to oxidative stress [PMID:20847055]"
FT                   /protein_id="DAA07537.1"
FT                   /translation="MMNEDISIIDGHNSFLTEKSTVLLTQAKRTLEDEKEMITPPSSTV
FT                   RKTMKEVNKRPSHPLSPDHSSPIAPSKAKRQRSDTCARSNGNLTLEEILQSLERRRING
FT                   ELAKKPPYSYATLICLAILQSQEGKLTLSQIYHWIHVHFPYYKQKDASWQNSIRHNLSL
FT                   NDAFIKTEKSCDGKGHFWEVRPGAETKFFKGENRGYEFVKDSLQDIGKYFEIDSTLDEL
FT                   EQVESGEGNDDLPDEEEREEAGKFPSIEIQLNSSPILRVSQLHHIPQLKTDNSVLNPHE
FT                   NLESMRNMIENDVNNIDSLEPPYVMKKYHTSLGLPSLVNAKDHFQAGVKNNNITQANRF
FT                   NTLPITSAKSPQNFRKYFTSFNSNFEDLSPLRSNVGAGSLLDPLPYSPLKLYDQKNLAL
FT                   MSKPQSQQSYSNSQLPPPPSSHGSDLLKTPKMRHSDGLEKTPSRLISTPKDGNSILRKW
FT                   QTPSHLFEDLYCSPLFRAIETPIRYITTPGGTLETQISPRKSSAPDVLTSATNSKFASS
FT                   GLFGVDVYSVWKRATEKISDGNNTTDSNQKHHPYHNHPSNDSGNEKN"
FT   gene            231500..232963
FT                   /gene="RAD18"
FT                   /locus_tag="YCR066W"
FT   mRNA            231500..232963
FT                   /gene="RAD18"
FT                   /locus_tag="YCR066W"
FT                   /product="E3 ubiquitin-protein ligase RAD18"
FT   CDS_pept        231500..232963
FT                   /codon_start=1
FT                   /gene="RAD18"
FT                   /locus_tag="YCR066W"
FT                   /product="E3 ubiquitin-protein ligase RAD18"
FT                   /EC_number="2.3.2.27"
FT                   /note="E3 ubiquitin ligase; forms heterodimer with Rad6p to
FT                   monoubiquitinate PCNA-K164; heterodimer binds
FT                   single-stranded DNA and has single-stranded DNA dependent
FT                   ATPase activity; required for postreplication repair;
FT                   SUMO-targeted ubiquitin ligase (STUbl) that contains a
FT                   SUMO-interacting motif (SIM) which stimulates its ubiquitin
FT                   ligase activity towards the sumoylated form of PCNA"
FT                   /db_xref="GOA:P10862"
FT                   /db_xref="InterPro:IPR001841"
FT                   /db_xref="InterPro:IPR003034"
FT                   /db_xref="InterPro:IPR004580"
FT                   /db_xref="InterPro:IPR006642"
FT                   /db_xref="InterPro:IPR013083"
FT                   /db_xref="InterPro:IPR017907"
FT                   /db_xref="InterPro:IPR039577"
FT                   /db_xref="UniProtKB/Swiss-Prot:P10862"
FT                   /experiment="EXISTENCE:direct assay:GO:0000790 nuclear
FT                   chromatin [PMID:10880451]"
FT                   /experiment="EXISTENCE:direct assay:GO:0003697
FT                   single-stranded DNA binding [PMID:9287349|PMID:7926769]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
FT                   [PMID:10880451]"
FT                   /experiment="EXISTENCE:direct assay:GO:0017116
FT                   single-stranded DNA helicase activity [PMID:9287349]"
FT                   /experiment="EXISTENCE:direct assay:GO:0097505 Rad6-Rad18
FT                   complex [PMID:9287349]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0042275
FT                   error-free postreplication DNA repair
FT                   [PMID:10924462|PMID:9576943]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0042276
FT                   error-prone translesion synthesis
FT                   [PMID:11973297|PMID:15687278]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0070987
FT                   error-free translesion synthesis [PMID:9409821]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006513 protein
FT                   monoubiquitination [PMID:12226657]"
FT                   /protein_id="DAA07538.1"
FT                   /translation="MDHQITTASDFTTTSIPSLYQLDTLLRCHICKDFLKVPVLTPCGH
FT                   TFCSLCIRTHLNNQPNCPLCLFEFRESLLRSEFLVSEIIQSYTSLRSSLLDALRIPKPT
FT                   PVPENEEVPGPENSSWIELISESESDSVNAADDDLQIVATSERKLAKRSMTDILPLSSK
FT                   PSKRNFAMFRSERIKKKSKPNEQMAQCPICQQFYPLKALEKTHLDECLTLQSLGKKPKI
FT                   STTFPTESNPHNKSSSRFKVRTPEVDKSSCGETSHVDKYLNSMMSAEHQRLPKINFTSM
FT                   TQSQIKQKLSSLGLSTNGTRQNMIKRYNHYEMLWNSNFCDSLEPVDEAELKRQLLSWDV
FT                   SHNKTPQNSSNKGGISKLMIMKSNGKSSSYRKLLENFKNDKFNRKGWMVMFRKDFARLI
FT                   REAKMKIKTGSSDSSGSVGHSNDGDGVEKVQSDQGTEDQQMEKDQDTVINEDRVAGERN
FT                   LPNEDSTDADLSRELMDLNEYSKDPPGNN"
FT   gene            complement(233125..236322)
FT                   /gene="SED4"
FT                   /locus_tag="YCR067C"
FT   mRNA            complement(233125..236322)
FT                   /gene="SED4"
FT                   /locus_tag="YCR067C"
FT                   /product="Sed4p"
FT   CDS_pept        complement(233125..236322)
FT                   /codon_start=1
FT                   /gene="SED4"
FT                   /locus_tag="YCR067C"
FT                   /product="Sed4p"
FT                   /note="Integral ER membrane protein that stimulates Sar1p
FT                   GTPase activity; involved in COPII vesicle budding through
FT                   disassociation of coat proteins from membranes onto
FT                   liposomes; binds Sec16p; SED4 has a paralog, SEC12, that
FT                   arose from the whole genome duplication"
FT                   /db_xref="GOA:P25365"
FT                   /db_xref="InterPro:IPR001680"
FT                   /db_xref="InterPro:IPR015943"
FT                   /db_xref="InterPro:IPR017986"
FT                   /db_xref="InterPro:IPR036322"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25365"
FT                   /experiment="EXISTENCE:direct assay:GO:0003400 regulation
FT                   of COPII vesicle coating [PMID:21291503]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005096 GTPase
FT                   activator activity [PMID:21291503]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
FT                   [PMID:24390141]"
FT                   /experiment="EXISTENCE:direct assay:GO:0030176 integral
FT                   component of endoplasmic reticulum membrane [PMID:7593162]"
FT                   /experiment="EXISTENCE:direct assay:GO:0043547 positive
FT                   regulation of GTPase activity [PMID:21291503]"
FT                   /experiment="EXISTENCE:physical interaction:GO:0043547
FT                   positive regulation of GTPase activity [PMID:21291503]"
FT                   /protein_id="DAA07539.1"
FT                   /translation="MSGNSANYDVGYPIYGAKFINEGTLLVAGGGGQFNSSFPNKITAL
FT                   KVNFQKKKHIRRFREITLDSIDDAPTSLDCNNNLILVGCNELFNDSSMENVNHHLRKFV
FT                   FEQEHLKFVASIDFNRTTDPSVFTKFVYINQRATVAAIASSEVPTVIRIIDPRNLTENY
FT                   EIETGREVNDLHFAPNGILLSYITSNSLEVASVRDGNFVARKTDFDKNLVLSNIRFLND
FT                   NTLLVAASLSNSDGVSLLKLGVSSKGVKILKTASFMFDLNGITSMDVSPNKKFVALSSN
FT                   DNLVAIVSVEKLKLVQLVPRVHESTITKVTFSPDSRYLASTSMGNTINVLKLSGTSSSI
FT                   LRNIWKFFLNFVLLVVLAGAIQLGYKHNVHGFIYKHAHDIYKSKFKENTTIDQGSSSYF
FT                   TINDDYRGITESADIISATDVASDIETEFSSFDTSTMRTTTEDEQKFVWISSSADSQFT
FT                   SADIPTSASSSSSSSSSSFYEESVTNEPIVSSPTSEITKPLASPTEPNIVEKPSLPLNS
FT                   ESIDLLSSSSNSITEYPEPTPDLEEKLSSLIVEQSESEITTDRESVSKLLSTESPSLSH
FT                   MPSSSSSSLSLSSSLTTSPTTALSTSTATAVTTTQTNPTNDAANTSFLDNSKPASTREI
FT                   YKTKIITEVITKIEYRNIPASDSNAEAEQYVTTSSSMLLTPTDTMVSSPVSEIDPIASE
FT                   LERMVETPTHSISIASEFDSVASNLIPNEEILSTSASQDSISSHPSTFSDSSITSGFQS
FT                   IEVSTVTSSVLASESIPSISDSTFSKFHSISEPVSSAIVETATSSFSKTETKTSRVIAF
FT                   STEDSERSSALIDNSEYTSVLADNLEPTSVLADNSEPTSVLADSSEPTSVFTDAVQSPK
FT                   TSVGQSSLSESTNIEGTSMASMIFSSSGASIGALSDIGKGTLSVESASSTVAQPMPGVT
FT                   TTAPSFVSSPHKISASSIDASGFVQKEIMIEVQSSKDSSEAFGVRHKISENVNTPVSRM
FT                   LTTEMQASGTVDVTEDVSLSSEVISALNVEITSLPNPVAPPQTIAAPLNNNSNTNIVND
FT                   DNAVAGTVNYAGLHDEL"
FT   gene            237214..238776
FT                   /gene="ATG15"
FT                   /gene_synonym="AUT5"
FT                   /gene_synonym="CVT17"
FT                   /locus_tag="YCR068W"
FT   mRNA            237214..238776
FT                   /gene="ATG15"
FT                   /gene_synonym="AUT5"
FT                   /gene_synonym="CVT17"
FT                   /locus_tag="YCR068W"
FT                   /product="triglyceride lipase ATG15"
FT   CDS_pept        237214..238776
FT                   /codon_start=1
FT                   /gene="ATG15"
FT                   /gene_synonym="AUT5"
FT                   /gene_synonym="CVT17"
FT                   /locus_tag="YCR068W"
FT                   /product="triglyceride lipase ATG15"
FT                   /EC_number="3.1.1.3"
FT                   /note="Phospholipase; preferentially hydrolyses
FT                   phosphatidylserine, with minor activity against cardiolipin
FT                   and phosphatidylethanolamine; required for lysis of
FT                   autophagic and CVT bodies; targeted to intravacuolar
FT                   vesicles during autophagy via the multivesicular body (MVB)
FT                   pathway; required for the maintenance of lipid droplet
FT                   quantity after the diauxic shift; regulates lipolysis;
FT                   expression regulated by Yap1p during autophagy"
FT                   /db_xref="GOA:P25641"
FT                   /db_xref="InterPro:IPR002921"
FT                   /db_xref="InterPro:IPR029058"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25641"
FT                   /experiment="EXISTENCE:direct assay:GO:0004620
FT                   phospholipase activity [PMID:27543826]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005775 vacuolar
FT                   lumen [PMID:11566994]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
FT                   reticulum [PMID:26928762]"
FT                   /experiment="EXISTENCE:direct assay:GO:0006624 vacuolar
FT                   protein processing [PMID:11085977]"
FT                   /experiment="EXISTENCE:direct assay:GO:0006660
FT                   phosphatidylserine catabolic process [PMID:27543826]"
FT                   /experiment="EXISTENCE:direct assay:GO:0006914 autophagy
FT                   [PMID:11085977|PMID:11566994]"
FT                   /experiment="EXISTENCE:direct assay:GO:0016021 integral
FT                   component of membrane [PMID:11085977]"
FT                   /experiment="EXISTENCE:direct assay:GO:0030397 membrane
FT                   disassembly [PMID:11085977]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000425
FT                   pexophagy [PMID:31332264]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0004620
FT                   phospholipase activity [PMID:27543826]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006624 vacuolar
FT                   protein processing [PMID:11085977]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006660
FT                   phosphatidylserine catabolic process [PMID:27543826]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006914
FT                   autophagy [PMID:11085977|PMID:11566994]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0030397 membrane
FT                   disassembly [PMID:11085977]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0034496
FT                   multivesicular body membrane disassembly [PMID:12499386]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0034727
FT                   piecemeal microautophagy of the nucleus [PMID:18701704]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0046461 neutral
FT                   lipid catabolic process [PMID:26061644]"
FT                   /protein_id="DAA07540.1"
FT                   /translation="MLHKSPSRKRFASPLHLGCILTLTVLCLIAYYFALPDYLSVGKSS
FT                   SRGAMDQKSDGTFRLKSIYRHGVGANHRLHQRLEVTPEVISAAGMLYQETTTQGQDFED
FT                   QEPLWTTNAEYATTNPFDFEFELRRMPLLMKRMKERDPEFIESYIYGETYMTEEEEHAM
FT                   WIDDDIVAPNITDRGTVVSLALMSSNAYVRIPQTGDWRNVTEPWNETEPEDFGWDGDGI
FT                   RGHVFYNEVENIVVLSIKGTSAQGLPGSGEDETTGNDKINDNLLFSCCCARVSYLWTTV
FT                   CDCYVKSYICDESCLEKELRRKDRFYSAVVDIYKGVLKEYPDAAIWVTGHSLGGALASL
FT                   LGRTFGLPAVAFESPGELLPSKRLHLPFPPGLPSYMEGIWHFGHNADPIFMGTCNGASS
FT                   SCSLVGYAMETACHTGRVCVYDVVNDKGWSVNMFNHRIHKVIDEVLLGYEQAAKCVEPE
FT                   PCVDCYNWKFIPSRDWESSSRLITKTKSHAAPTTTTRTTATTTSSSTCVGRNWLGFCTK
FT                   YEL"
FT   gene            239055..240011
FT                   /gene="CPR4"
FT                   /gene_synonym="CYP4"
FT                   /gene_synonym="SCC3"
FT                   /gene_synonym="YCR070W"
FT                   /locus_tag="YCR069W"
FT   mRNA            239055..240011
FT                   /gene="CPR4"
FT                   /gene_synonym="CYP4"
FT                   /gene_synonym="SCC3"
FT                   /gene_synonym="YCR070W"
FT                   /locus_tag="YCR069W"
FT                   /product="peptidylprolyl isomerase family protein CPR4"
FT   CDS_pept        239055..240011
FT                   /codon_start=1
FT                   /gene="CPR4"
FT                   /gene_synonym="CYP4"
FT                   /gene_synonym="SCC3"
FT                   /gene_synonym="YCR070W"
FT                   /locus_tag="YCR069W"
FT                   /product="peptidylprolyl isomerase family protein CPR4"
FT                   /EC_number="5.2.1.8"
FT                   /note="Peptidyl-prolyl cis-trans isomerase (cyclophilin);
FT                   catalyzes the cis-trans isomerization of peptide bonds
FT                   N-terminal to proline residues; has a potential role in the
FT                   secretory pathway; CPR4 has a paralog, CPR8, that arose
FT                   from the whole genome duplication"
FT                   /db_xref="GOA:P25334"
FT                   /db_xref="InterPro:IPR002130"
FT                   /db_xref="InterPro:IPR029000"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25334"
FT                   /experiment="EXISTENCE:direct assay:GO:0000324 fungal-type
FT                   vacuole [PMID:26928762]"
FT                   /protein_id="DAA07541.1"
FT                   /translation="MWLKSLLLCLYSLVLCQVHAAPSSGKQITSKDVDLQKKYEPSPPA
FT                   THRGIITIEYFDPVSKSMKEADLTFELYGTVVPKTVNNFAMLAHGVKAVIEGKDPNDIH
FT                   TYSYRKTKINKVYPNKYIQGGVVAPDVGPFTVYGPKFDDENFYLKHDRPERLAMAYFGP
FT                   DSNTSEFIITTKADGNEELDGKSVVFGQITSGLDQLMDAIQYTETDEYGKPQHELRFLY
FT                   FVLEILKISNILDLHAAYTEKVEKFRNGDVSVGSTLENIFRNDKAYTPLTTSTGTTAYD
FT                   LNHPISRALMCLTVLGLCFIAYKGMHEKPHTVSLRHK"
FT   gene            complement(240103..240543)
FT                   /gene="IMG2"
FT                   /gene_synonym="mL49"
FT                   /locus_tag="YCR071C"
FT   mRNA            complement(240103..240543)
FT                   /gene="IMG2"
FT                   /gene_synonym="mL49"
FT                   /locus_tag="YCR071C"
FT                   /product="mitochondrial 54S ribosomal protein IMG2"
FT   CDS_pept        complement(240103..240543)
FT                   /codon_start=1
FT                   /gene="IMG2"
FT                   /gene_synonym="mL49"
FT                   /locus_tag="YCR071C"
FT                   /product="mitochondrial 54S ribosomal protein IMG2"
FT                   /note="Mitochondrial ribosomal protein of the large
FT                   subunit; conserved in metazoa, with similarity to human
FT                   mitochondrial ribosomal protein MRPL49"
FT                   /db_xref="GOA:P25642"
FT                   /db_xref="InterPro:IPR007740"
FT                   /db_xref="PDB:3J6B"
FT                   /db_xref="PDB:5MRC"
FT                   /db_xref="PDB:5MRE"
FT                   /db_xref="PDB:5MRF"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25642"
FT                   /experiment="EXISTENCE:curator inference:GO:0032543
FT                   mitochondrial translation [PMID:12392552]"
FT                   /experiment="EXISTENCE:direct assay:GO:0003735 structural
FT                   constituent of ribosome [PMID:12392552]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005739
FT                   mitochondrion [PMID:16823961|PMID:24769239]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005762
FT                   mitochondrial large ribosomal subunit [PMID:12392552]"
FT                   /protein_id="DAA07542.1"
FT                   /translation="MISSCVTRCFGRGKCLPGPATASIYQTIRCISTNSNKAAEAPIFP
FT                   KLEDVKMHELIGNNNFGKKTYYVERSRTGNLPVYSAYKNGGNKIITEIRKIEGDVIQLR
FT                   NDLQEQLPFIPKKSWSVVMQSKKIIIKGNAVEAVKRVLTKKF"
FT   gene            complement(240805..242352)
FT                   /gene="RSA4"
FT                   /locus_tag="YCR072C"
FT   mRNA            complement(240805..242352)
FT                   /gene="RSA4"
FT                   /locus_tag="YCR072C"
FT                   /product="Rsa4p"
FT   CDS_pept        complement(240805..242352)
FT                   /codon_start=1
FT                   /gene="RSA4"
FT                   /locus_tag="YCR072C"
FT                   /product="Rsa4p"
FT                   /note="Ribosomal large subunit (60S) assembly factor;
FT                   association of the N-terminal ubiquitin-like (UBL) domain
FT                   of this preribosomal factor with the MIDAS domain in the
FT                   Rea1p tail, promoted by the GTPase Nog2p, is required for
FT                   the ATP-dependent dissociation of preribosomal factors
FT                   including the Rix1p subcomplex, Rea1p, Nog2p and Rsa1p
FT                   itself prior to nuclear export of pre-60S particles;
FT                   contains WD-repeats and a UBL domain; localizes to the
FT                   nucleolus"
FT                   /db_xref="GOA:P25382"
FT                   /db_xref="InterPro:IPR001680"
FT                   /db_xref="InterPro:IPR012972"
FT                   /db_xref="InterPro:IPR015943"
FT                   /db_xref="InterPro:IPR017986"
FT                   /db_xref="InterPro:IPR019775"
FT                   /db_xref="InterPro:IPR020472"
FT                   /db_xref="InterPro:IPR036322"
FT                   /db_xref="PDB:3JCT"
FT                   /db_xref="PDB:4V7F"
FT                   /db_xref="PDB:4WJU"
FT                   /db_xref="PDB:4WJV"
FT                   /db_xref="PDB:5FL8"
FT                   /db_xref="PDB:5JCS"
FT                   /db_xref="PDB:6FT6"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25382"
FT                   /experiment="EXISTENCE:direct assay:GO:0005730 nucleolus
FT                   [PMID:16221974]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000027
FT                   ribosomal large subunit assembly [PMID:16221974]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0110136
FT                   protein-RNA complex remodeling [PMID:19737519]"
FT                   /protein_id="DAA07543.1"
FT                   /translation="MSTLIPPPSKKQKKEAQLPREVAIIPKDLPNVSIKFQALDTGDNV
FT                   GGALRVPGAISEKQLEELLNQLNGTSDDPVPYTFSCTIQGKKASDPVKTIDITDNLYSS
FT                   LIKPGYNSTEDQITLLYTPRAVFKVKPVTRSSSAIAGHGSTILCSAFAPHTSSRMVTGA
FT                   GDNTARIWDCDTQTPMHTLKGHYNWVLCVSWSPDGEVIATGSMDNTIRLWDPKSGQCLG
FT                   DALRGHSKWITSLSWEPIHLVKPGSKPRLASSSKDGTIKIWDTVSRVCQYTMSGHTNSV
FT                   SCVKWGGQGLLYSGSHDRTVRVWDINSQGRCINILKSHAHWVNHLSLSTDYALRIGAFD
FT                   HTGKKPSTPEEAQKKALENYEKICKKNGNSEEMMVTASDDYTMFLWNPLKSTKPIARMT
FT                   GHQKLVNHVAFSPDGRYIVSASFDNSIKLWDGRDGKFISTFRGHVASVYQVAWSSDCRL
FT                   LVSCSKDTTLKVWDVRTRKLSVDLPGHKDEVYTVDWSVDGKRVCSGGKDKMVRLWTH"
FT   gene            complement(242588..246583)
FT                   /gene="SSK22"
FT                   /locus_tag="YCR073C"
FT   mRNA            complement(242588..246583)
FT                   /gene="SSK22"
FT                   /locus_tag="YCR073C"
FT                   /product="mitogen-activated protein kinase kinase kinase
FT                   SSK22"
FT   CDS_pept        complement(242588..246583)
FT                   /codon_start=1
FT                   /gene="SSK22"
FT                   /locus_tag="YCR073C"
FT                   /product="mitogen-activated protein kinase kinase kinase
FT                   SSK22"
FT                   /EC_number="2.7.11.1"
FT                   /note="MAP kinase kinase kinase of HOG1 mitogen-activated
FT                   signaling pathway; functionally redundant with Ssk2p;
FT                   interacts with and is activated by Ssk1p; phosphorylates
FT                   Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole
FT                   genome duplication"
FT                   /db_xref="GOA:P25390"
FT                   /db_xref="InterPro:IPR000719"
FT                   /db_xref="InterPro:IPR008271"
FT                   /db_xref="InterPro:IPR011009"
FT                   /db_xref="InterPro:IPR017240"
FT                   /db_xref="InterPro:IPR017441"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25390"
FT                   /experiment="EXISTENCE:direct assay:GO:0004672 protein
FT                   kinase activity [PMID:16319894]"
FT                   /experiment="EXISTENCE:direct assay:GO:0006468 protein
FT                   phosphorylation [PMID:16319894]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0000161
FT                   osmosensory signaling MAPK cascade
FT                   [PMID:7624781|PMID:9742096]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000161
FT                   osmosensory signaling MAPK cascade [PMID:7624781]"
FT                   /protein_id="DAA07544.1"
FT                   /translation="MMMDILNTQQQKAAEGGRVLAPHTISSKLVKRLSSHSSHKLSRSD
FT                   LKALGGSETISDGPSQLTFKDRYVFNESLYLKKLKKTALDDYYTRGIKLTNRYEEDDGD
FT                   DEIIRLSNGDRIDEDLHSGVKFFSTTPYCRKMRSDSDELAWNEIATERFKWQSMLARVL
FT                   KGDIVKGEKTRIANQVKKPGLNKELSDEIWLELKAWLNGRTMQEMEQSLTYLRDSSDSV
FT                   FEEIMKFQIPQGKILSLDALEAILQDLMNRYHSVVSYWPNLKKMYKDKPITNTAEFTAR
FT                   IDVMNSWLNFKTNLTLRRQELDDWINRFSPISSSDNCQEDFDGVPQWNCKMKILAEQLM
FT                   KEKNIESIFQKKIFYPLSPWMFKLKLHFIVYRETLTKMNIKYPYERLRSLLAFPVYLIK
FT                   EVILTRLSYARKLKNPTMMMIDQMIDDFNAFIRLSVQLKYTLTKYCSNLPFDVDFDPTF
FT                   ENTVIEAIRYLFFLLNLKLIDSSKQNFKAPDLLLKYWDHLKNTGHYINGAETVIPNEFL
FT                   KLTLRLVHKLQFYLLKQQNFPPTFANASEAEKWLSSIFENLGAMKRKLNRFSNILVKAF
FT                   QNSAVYQINHNAQLVKKLKDAHYFLVYSGNTFESSGVYMFAAPELLGCDNDTILRILRN
FT                   KSIGCDLVPKLDIGNNLNVYDITTKETDLNILVSKGEDSKGIPYYRVVANSSSDLDRHA
FT                   HQSKKKNFSTDPFDQHLDEKNNEVFELEVALSSLGALVVLYPGEPVVWDGPVYKLPGNN
FT                   LFASNEMDLGKIGNPNTLILLNQGSNYALTYQIDKFNQTVGDSVSFIEKRCSLNSIESS
FT                   LQKINKAYYKLTYTVLNNYKGILGSFMKQCPGNELLNSIFMFGRDFGRSFLKYNAFSSK
FT                   RKYVIIFLMVKLGMNWLKFLVEECDPTDQRTFRWCVLAMDFAMQMTSGYNILALNVKQF
FT                   QELKERVSVCMSLLISHFDVMGARATEAENGMQQARLNIDTEENIDEEATLEINSRLRL
FT                   EAIKTLEKTMKRNPRQMGKVLDATDQGNKYLLSLASSLSNVSMRWQKRSFIGGGTFGQV
FT                   YSAINLENGEILAVKEIKIHDTTTMKKIFPLIKEEMTVLEMLNHPNIVQYYGVEVHRDK
FT                   VNIFMEYCEGGSLASLLDHGRIEDEMVTQVYTFELLEGLAYLHQSGVVHRDIKPENILL
FT                   DFNGIIKYVDFGTARTVVGSRTRTVRNAAVQDFGVETKSLNEMMGTPMYMAPETISGSA
FT                   VKGKLGADDVWALGCVVLEMATGRRPWSNLDNEWAIMYHVAAGRIPQLPNRDEMTAAGR
FT                   AFLERCLVQDPTMRATAVELLIDPWMIQIREIAFGNSEKDQVPILSS"
FT   gene            246963..247910
FT                   /gene="SOL2"
FT                   /gene_synonym="YCRX13W"
FT                   /locus_tag="YCR073W-A"
FT   mRNA            246963..247910
FT                   /gene="SOL2"
FT                   /gene_synonym="YCRX13W"
FT                   /locus_tag="YCR073W-A"
FT                   /product="Sol2p"
FT   CDS_pept        246963..247910
FT                   /codon_start=1
FT                   /gene="SOL2"
FT                   /gene_synonym="YCRX13W"
FT                   /locus_tag="YCR073W-A"
FT                   /product="Sol2p"
FT                   /note="Protein with a possible role in tRNA export; shows
FT                   similarity to 6-phosphogluconolactonase non-catalytic
FT                   domains but does not exhibit this enzymatic activity;
FT                   homologous to Sol3p and Sol4p; SOL2 has a paralog, SOL1,
FT                   that arose from the whole genome duplication"
FT                   /db_xref="GOA:P37262"
FT                   /db_xref="InterPro:IPR005900"
FT                   /db_xref="InterPro:IPR006148"
FT                   /db_xref="InterPro:IPR037171"
FT                   /db_xref="InterPro:IPR039104"
FT                   /db_xref="UniProtKB/Swiss-Prot:P37262"
FT                   /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
FT                   [PMID:14562095]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005829 cytosol
FT                   [PMID:15454531]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006409 tRNA
FT                   export from nucleus [PMID:15454531]"
FT                   /protein_id="DAA07545.1"
FT                   /translation="MTTTVPKIFAFHEFSDVAEAVADHVVHAQDGALAPKNERKHSVPN
FT                   ISMNALDMTREASCKSTASAAEGKSGSSGSGSGSSKPKKEKRFKIALSGGSLIEVLHEG
FT                   LLKRDDVRWGDWDIYFADERLVPFSSNESNYGCAKRKILDLIDTAKYGTPKVYHIDESL
FT                   IDDPQECADNYEKVLIRGFAGRDSVKLPMFDLFLLGCAPDGHIASLFPNFQDNLREKLA
FT                   WVVPVENAPSGPSTRISLTIPVICHSHRVTFVVEGATKAPIIKTIMERPEKGLPSSIVN
FT                   EGAAGRVSWFVDDDALTDVLVTKKKYKFHQGLSI"
FT   gene            complement(248033..248815)
FT                   /gene="ERS1"
FT                   /locus_tag="YCR075C"
FT   mRNA            complement(248033..248815)
FT                   /gene="ERS1"
FT                   /locus_tag="YCR075C"
FT                   /product="cystinosin-like protein ERS1"
FT   CDS_pept        complement(248033..248815)
FT                   /codon_start=1
FT                   /gene="ERS1"
FT                   /locus_tag="YCR075C"
FT                   /product="cystinosin-like protein ERS1"
FT                   /note="Protein involved in cystine transport; localizes to
FT                   the vacuole, plasma membrane and endosome; similarity to
FT                   human cystinosin, a H(+)-driven transporter involved in
FT                   L-cystine export from lysosomes and implicated in the
FT                   disease cystinosis; contains seven transmembrane domains;
FT                   mutation is functionally complemented by human CTNS"
FT                   /db_xref="GOA:P17261"
FT                   /db_xref="InterPro:IPR005282"
FT                   /db_xref="InterPro:IPR006603"
FT                   /db_xref="UniProtKB/Swiss-Prot:P17261"
FT                   /experiment="EXISTENCE:direct assay:GO:0000324 fungal-type
FT                   vacuole [PMID:15885099|PMID:27142334]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005768 endosome
FT                   [PMID:15885099]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005886 plasma
FT                   membrane [PMID:27142334]"
FT                   /experiment="EXISTENCE:direct assay:GO:0015811 L-cystine
FT                   transport [PMID:27142334]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0015184
FT                   L-cystine transmembrane transporter activity
FT                   [PMID:15885099]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0015811
FT                   L-cystine transport [PMID:15885099]"
FT                   /protein_id="DAA07546.1"
FT                   /translation="MVSLDDILGIVYVTSWSISMYPPIITNWRHKSASAISMDFVMLNT
FT                   AGYSYLVISIFLQLYCWKMTGDESDLGRPKLTQFDFWYCLHGCLMNVVLLTQVVAGARI
FT                   WRFPGKGHRKMNPWYLRILLASLAIFSLLTVQFMYSNYWYDWHNSRTLAYCNNLFLLKI
FT                   SMSLIKYIPQVTHNSTRKSMDCFPIQGVFLDVTGGIASLLQLIWQLSNDQGFSLDTFVT
FT                   NFGKVGLSMVTLIFNFIFIMQWFVYRSRGHDLASEYPL"
FT   gene            248975..249202
FT                   /gene="EGO2"
FT                   /locus_tag="YCR075W-A"
FT   mRNA            248975..249202
FT                   /gene="EGO2"
FT                   /locus_tag="YCR075W-A"
FT                   /product="Ego2p"
FT   CDS_pept        248975..249202
FT                   /codon_start=1
FT                   /gene="EGO2"
FT                   /locus_tag="YCR075W-A"
FT                   /product="Ego2p"
FT                   /note="Subunit of the EGO/GSE complex; the
FT                   vacuolar/endosomal membrane associated EGO/GSE complex
FT                   regulates exit from rapamycin-induced growth arrest,
FT                   stimulating microautophagy and sorting of Gap1p from the
FT                   endosome to the plasma membrane; identified by homology to
FT                   Ashbya gossypii; EGO2 has a paralog, EGO4, that arose from
FT                   the whole genome duplication"
FT                   /db_xref="EnsemblGenomes-Gn:YCR075W-A"
FT                   /db_xref="EnsemblGenomes-Tr:YCR075W-A"
FT                   /db_xref="GOA:Q3E830"
FT                   /db_xref="InterPro:IPR021591"
FT                   /db_xref="InterPro:IPR035098"
FT                   /db_xref="PDB:4XPM"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q3E830"
FT                   /experiment="EXISTENCE:direct assay:GO:0000329 fungal-type
FT                   vacuole membrane [PMID:26206314]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0038202 TORC1
FT                   signaling [PMID:26206314]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0072665 protein
FT                   localization to vacuole [PMID:26206314]"
FT                   /experiment="EXISTENCE:physical interaction:GO:0034448 EGO
FT                   complex [PMID:26206314]"
FT                   /protein_id="DAA07547.1"
FT                   /translation="MEAEKQSDIKGTIAFDTHGNVIESTGVGSQRIEDIGDLSKVTLDA
FT                   EGFAQVQGDSLLVHLYKRNDITLAVYTSAQ"
FT   gene            complement(249293..250045)
FT                   /gene="FUB1"
FT                   /locus_tag="YCR076C"
FT   mRNA            complement(249293..250045)
FT                   /gene="FUB1"
FT                   /locus_tag="YCR076C"
FT                   /product="Fub1p"
FT   CDS_pept        complement(249293..250045)
FT                   /codon_start=1
FT                   /gene="FUB1"
FT                   /locus_tag="YCR076C"
FT                   /product="Fub1p"
FT                   /note="Proteasome-binding protein; interacts physically
FT                   with multiple subunits of the 20S proteasome and
FT                   genetically with genes encoding 20S core particle and 19S
FT                   regulatory particle subunits; exhibits boundary activity
FT                   which blocks the propagation of heterochromatic silencing;
FT                   contains a PI31 proteasome regulator domain and sequence
FT                   similarity with human PSMF1, a proteasome inhibitor; not an
FT                   essential gene"
FT                   /db_xref="GOA:P25659"
FT                   /db_xref="InterPro:IPR013886"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25659"
FT                   /experiment="EXISTENCE:direct assay:GO:0070628 proteasome
FT                   binding [PMID:22362029]"
FT                   /protein_id="DAA07548.1"
FT                   /translation="MIENKVELVAELVLESIGKTEVVSRHTEGTKSCQVSFRIKDSPSE
FT                   KGSTSFLSELVVIQTLDDNDKYTVVIRHGTSITMACVVGYSDFKLPTELKWPLERESLP
FT                   VEPDLKPIMTQLKRQTAGSADMPKFDDEYQAQARQNQGTAPLNPYPGLTVTEPSFANPA
FT                   GGYADGDLYPVGTSHPDWSGGLPNPLGNPSSQGGMIFDPNRRPAPRREDMPPGWMPGSK
FT                   YDEPFGPGSGGFGGSGSGGFGGSGSGFI"
FT   gene            complement(250238..252628)
FT                   /gene="PAT1"
FT                   /gene_synonym="MRT1"
FT                   /locus_tag="YCR077C"
FT   mRNA            complement(250238..252628)
FT                   /gene="PAT1"
FT                   /gene_synonym="MRT1"
FT                   /locus_tag="YCR077C"
FT                   /product="Pat1p"
FT   CDS_pept        complement(250238..252628)
FT                   /codon_start=1
FT                   /gene="PAT1"
FT                   /gene_synonym="MRT1"
FT                   /locus_tag="YCR077C"
FT                   /product="Pat1p"
FT                   /note="Deadenylation-dependent mRNA-decapping factor; also
FT                   required for faithful chromosome transmission, maintenance
FT                   of rDNA locus stability, and protection of mRNA 3'-UTRs
FT                   from trimming; associated with topoisomerase II; binds to
FT                   mRNAs under glucose starvation, most often in the 3' UTR;
FT                   functionally linked to Pab1p; forms cytoplasmic foci upon
FT                   DNA replication stress; phosphorylation by PKA inhibits P
FT                   body foci formation"
FT                   /db_xref="GOA:P25644"
FT                   /db_xref="InterPro:IPR019167"
FT                   /db_xref="InterPro:IPR039900"
FT                   /db_xref="PDB:4BRW"
FT                   /db_xref="PDB:4C8Q"
FT                   /db_xref="PDB:4N0A"
FT                   /db_xref="PDB:4OGP"
FT                   /db_xref="PDB:4OJJ"
FT                   /db_xref="PDB:5LM5"
FT                   /db_xref="PDB:5LMF"
FT                   /db_xref="PDB:5LMG"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25644"
FT                   /experiment="EXISTENCE:direct assay:GO:0000776 kinetochore
FT                   [PMID:23893485]"
FT                   /experiment="EXISTENCE:direct assay:GO:0000932 P-body
FT                   [PMID:12730603]"
FT                   /experiment="EXISTENCE:direct assay:GO:0003682 chromatin
FT                   binding [PMID:23706738]"
FT                   /experiment="EXISTENCE:direct assay:GO:0003723 RNA binding
FT                   [PMID:25035297]"
FT                   /experiment="EXISTENCE:direct assay:GO:0003729 mRNA binding
FT                   [PMID:23222640]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
FT                   [PMID:23706738]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
FT                   [PMID:23706738|PMID:22842922]"
FT                   /experiment="EXISTENCE:direct assay:GO:0010494 cytoplasmic
FT                   stress granule [PMID:23222640]"
FT                   /experiment="EXISTENCE:direct assay:GO:0022627 cytosolic
FT                   small ribosomal subunit [PMID:10779343]"
FT                   /experiment="EXISTENCE:direct assay:GO:0045947 negative
FT                   regulation of translational initiation [PMID:20832728]"
FT                   /experiment="EXISTENCE:direct assay:GO:1990726 Lsm1-7-Pat1
FT                   complex [PMID:24139796]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0033962
FT                   cytoplasmic mRNA processing body assembly [PMID:18981231]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000290
FT                   deadenylation-dependent decapping of nuclear-transcribed
FT                   mRNA [PMID:10913177]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000932 P-body
FT                   [PMID:12730603]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0001731
FT                   formation of translation preinitiation complex
FT                   [PMID:20832728]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006446
FT                   regulation of translational initiation [PMID:10779343]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0033962
FT                   cytoplasmic mRNA processing body assembly [PMID:18981231]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0045947 negative
FT                   regulation of translational initiation [PMID:20832728]"
FT                   /experiment="EXISTENCE:physical interaction:GO:0000290
FT                   deadenylation-dependent decapping of nuclear-transcribed
FT                   mRNA [PMID:10913177]"
FT                   /experiment="EXISTENCE:physical interaction:GO:0005515
FT                   protein binding [PMID:26952104]"
FT                   /protein_id="DAA07549.2"
FT                   /translation="MSFFGLENSGNARDGPLDFEESYKGYGEHELEENDYLNDETFGDN
FT                   VQVGTDFDFGNPHSSGSSGNAIGGNGVGATARSYVAATAEGISGPRTDGTAAAGPLDLK
FT                   PMESLWSTAPPPAMAPSPQSTMAPAPAPQQMAPLQPILSMQDLERQQRQMQQQFMNFHA
FT                   MGHPQGLPQGPPQQQFPMQPASGQPGPSQFAPPPPPPGVNVNMNQMPMGPVQVPVQASP
FT                   SPIGMSNTPSPGPVVGATKMPLQSGRRSKRDLSPEEQRRLQIRHAKVEKILKYSGLMTP
FT                   RDKDFITRYQLSQIVTEDPYNEDFYFQVYKIIQRGGITSESNKGLIARAYLEHSGHRLG
FT                   GRYKRTDIALQRMQSQVEKAVTVAKERPSKLKDQQAAAGNSSQDNKQANTVLGKISSTL
FT                   NSKNPRRQLQIPRQQPSDPDALKDVTDSLTNVDLASSGSSSTGSSAAAVASKQRRRSSY
FT                   AFNNGNGATNLNKSGGKKFILELIETVYEEILDLEANLRNGQQTDSTAMWEALHIDDSS
FT                   YDVNPFISMLSFDKGIKIMPRIFNFLDKQQKLKILQKIFNELSHLQIIILSSYKTTPKP
FT                   TLTQLKKVDLFQMIILKIIVSFLSNNSNFIEIMGLLLQLIRNNNVSFLTTSKIGLNLIT
FT                   ILISRAALIKQDSSRSNILSSPEISTWNEIYDKLFTSLESKIQLIFPPREYNDHIMRLQ
FT                   NDKFMDEAYIWQFLASLALSGKLNHQRIIIDEVRDEIFATINEAETLQKKEKELSVLPQ
FT                   RSQELDTELKSIIYNKEKLYQDLNLFLNVMGLVYRDGEISELK"
FT   gene            252845..254173
FT                   /gene="PTC6"
FT                   /gene_synonym="AUP1"
FT                   /gene_synonym="PPP2"
FT                   /locus_tag="YCR079W"
FT   mRNA            252845..254173
FT                   /gene="PTC6"
FT                   /gene_synonym="AUP1"
FT                   /gene_synonym="PPP2"
FT                   /locus_tag="YCR079W"
FT                   /product="type 2C protein phosphatase PTC6"
FT   CDS_pept        252845..254173
FT                   /codon_start=1
FT                   /gene="PTC6"
FT                   /gene_synonym="AUP1"
FT                   /gene_synonym="PPP2"
FT                   /locus_tag="YCR079W"
FT                   /product="type 2C protein phosphatase PTC6"
FT                   /EC_number="3.1.3.16"
FT                   /EC_number="3.1.3.43"
FT                   /note="Mitochondrial type 2C protein phosphatase (PP2C);
FT                   has similarity to mammalian PP1Ks; involved in mitophagy;
FT                   null mutant is sensitive to rapamycin and has decreased
FT                   phosphorylation of the Pda1 subunit of pyruvate
FT                   dehydrogenase"
FT                   /db_xref="GOA:P25646"
FT                   /db_xref="InterPro:IPR001932"
FT                   /db_xref="InterPro:IPR015655"
FT                   /db_xref="InterPro:IPR036457"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25646"
FT                   /experiment="EXISTENCE:direct assay:GO:0004722 protein
FT                   serine/threonine phosphatase activity [PMID:17002782]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005739
FT                   mitochondrion [PMID:14562095|PMID:24769239]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005758
FT                   mitochondrial intermembrane space [PMID:17166847]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005759
FT                   mitochondrial matrix [PMID:18180296]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0016236
FT                   macroautophagy [PMID:17166847]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000422
FT                   autophagy of mitochondrion [PMID:17166847]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0004741
FT                   [pyruvate dehydrogenase (lipoamide)] phosphatase activity
FT                   [PMID:18180296]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006470 protein
FT                   dephosphorylation [PMID:19840933]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0070262
FT                   peptidyl-serine dephosphorylation [PMID:18180296]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:1904184 positive
FT                   regulation of pyruvate dehydrogenase activity
FT                   [PMID:18180296]"
FT                   /protein_id="DAA07550.1"
FT                   /translation="MRLGNAYAYCKPSQNVGLKLDLLRGLPGYVGHATSRINRLENQDN
FT                   YSIKMMRSWPNAYGSALNCSVFDGHGEKGAQLSQLLADKLCSSLDFPEPSWDKQDLKKL
FT                   VQEYARRFPEGNYWKHKLSTFEKFYNKFIKNCNSKQELLLMKEGDSAILGQNGGRMIFD
FT                   KMGNIIDKIALLTELDRLRLFYGFARFDLDQCCGLGTAAGSTASSIFLYPYDDPNAPID
FT                   EGKDDDSWIISHSGLLKLIVTQVGDSKIILCDQDGIAHALTTTHHINSSRERHRLSIDP
FT                   SRLDPDAFGETRFLNNFANTRSFGDVAGKPYGISSEPDIFSFLVGNTLHLPRSERSKLP
FT                   FNGDECFLALVTDGITNKLADQEVVDLITSTVNSWGLKKATPQFVAEETIKFIQAIATK
FT                   HSDNATCVVVRLSNWGNWPNVDRTGPQRETKLMNAQSNETKLN"
FT   gene            254371..258654
FT                   /gene="SRB8"
FT                   /gene_synonym="GIG1"
FT                   /gene_synonym="MED12"
FT                   /gene_synonym="NUT6"
FT                   /gene_synonym="SSN5"
FT                   /gene_synonym="YCR080W"
FT                   /locus_tag="YCR081W"
FT   mRNA            254371..258654
FT                   /gene="SRB8"
FT                   /gene_synonym="GIG1"
FT                   /gene_synonym="MED12"
FT                   /gene_synonym="NUT6"
FT                   /gene_synonym="SSN5"
FT                   /gene_synonym="YCR080W"
FT                   /locus_tag="YCR081W"
FT                   /product="Srb8p"
FT   CDS_pept        254371..258654
FT                   /codon_start=1
FT                   /gene="SRB8"
FT                   /gene_synonym="GIG1"
FT                   /gene_synonym="MED12"
FT                   /gene_synonym="NUT6"
FT                   /gene_synonym="SSN5"
FT                   /gene_synonym="YCR080W"
FT                   /locus_tag="YCR081W"
FT                   /product="Srb8p"
FT                   /note="Subunit of the RNA polymerase II mediator complex;
FT                   associates with core polymerase subunits to form the RNA
FT                   polymerase II holoenzyme; essential for transcriptional
FT                   regulation; involved in glucose repression"
FT                   /db_xref="GOA:P25648"
FT                   /db_xref="InterPro:IPR019035"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25648"
FT                   /experiment="EXISTENCE:direct assay:GO:0003713
FT                   transcription coactivator activity [PMID:20505076]"
FT                   /experiment="EXISTENCE:direct assay:GO:0016592 mediator
FT                   complex [PMID:11383511|PMID:12200444]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000122 negative
FT                   regulation of transcription by RNA polymerase II
FT                   [PMID:16109375]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000411 positive
FT                   regulation of transcription by galactose [PMID:15601835]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0003713
FT                   transcription coactivator activity [PMID:20505076]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0045944 positive
FT                   regulation of transcription by RNA polymerase II
FT                   [PMID:15601835]"
FT                   /protein_id="DAA07551.1"
FT                   /translation="MNNGSGRYLLTPPDDLHPYVPSSKPQEQVYPDFKPWEHTAAEDQI
FT                   LANFVAKGFYHTPMVNFESISARSSVHESLVTQSNILSQQFDKIIKIREDHINKIPSNS
FT                   TTTLHGPGFQLPNRITLTDHRKETWLHELSSSHTSLVKIGKFIPHGLKRRQVIEQCYLK
FT                   FIPLKRAIWLIKCCYFIEWKSNHKKKRSNAAGADDAISMHLLKDWTDTFVYILEKLIFD
FT                   MTNHYNDSQQLRTWKRQISYFLKLLGNCYSLRLINKEIFHHWLVEFINKMENFEFLPLS
FT                   LHILMIFWNDICQIDTNAPVAATITSSQKEPFFLVTKITDMLLHKYYIVSSSKSMINDE
FT                   NYIINDIKKNNKIKLNILKILSSLILKIFQEQSLEVFIFPTSNWEIYKPLLFEIVSNAD
FT                   TNQNSDMKKKLELISYRNESLKNNSSIRNVIMSASNANDFQLTIVTCKQFPKLSCIQLN
FT                   CIDTQFTKLLDDNPTEFDWPTYVDQNPLTMHKIIQLILWSIHPSRQFDHYESNQLVAKL
FT                   LLLRINSTDEDLHEFQIEDAIWSLVFQLAKNFSAQKRVVSYMMPSLYRLLNILITYGII
FT                   KVPTYIRKLISSGLLYLQDSNDKFVHVQLLINLKISPLMKSQYNMVLRNVMEYDVKFYE
FT                   IFNFDQLVEITEQIKMRILSNDITNLQLSKTPLSIKIMVAEWYLSHLCSGILSSVNRTV
FT                   LLKIFKIFCIDLEVFHHFFKWIEFIVYHQLLSDIESLEALMDILLCYQKLFSQFINDHI
FT                   LFTKTFIFIYKKVLKEKDVPAYNVTSFMPFWKFFMKNFPFVLKVDNDLRIELQSVYNDE
FT                   KLKTEKLKNDKSEVLKVYSMINNSNQAVGQTWNFPEVFQVNIRFLLHNSEIIDTNTSKQ
FT                   FQKARNNVMLLIATNLKEYNKFMSIFLKRKDFTNKNLIQLISLKLLTFEVTQNVLGLEY
FT                   IIRLLPINLENNDGSYGLFLKYHKEQFIKSNFEKILLTCYELEKKYHGNECEINYYEIL
FT                   LKILITYGSSPKLLATSTKIIMLLLNDSVENSSNILEDILYYSTCPSETDLNDIPLGSG
FT                   QPDNDTVVTNDDKSDDDDHTVDEIDHVEYYVMMDFANLWVFQAFTCFCIKKIMENNEPA
FT                   MAMEDLKNFIFQIIEITNSNDLCSQIFDQLKDMQTIEMITQIVEKDFCTSCLQNNNQKI
FT                   DDNYIVVVIEIITSLSMRFQRETSGMIVISMENYHLLIKIIRQLSELNEGNLSKREIQI
FT                   DAVLKIFSFHQDSIFQRIIADLSADKPTSPFIDSICKLFDKISFNLRLKLFLYEILSSL
FT                   KSFAIYSSTIDAPAFHTSGKVELPKKLLNLPPFQVSSFVKETKLHSGDYGEEEDADQEE
FT                   SFSLNLGIGIVEIAHENEQKWLIYDKKDHKYVCTFSMEPYHFISNYNTKYTDDMATGSN
FT                   DTTAFNDSCVNLSLFDARFERKNPH"
FT   gene            258883..259269
FT                   /gene="AHC2"
FT                   /locus_tag="YCR082W"
FT   mRNA            258883..259269
FT                   /gene="AHC2"
FT                   /locus_tag="YCR082W"
FT                   /product="Ahc2p"
FT   CDS_pept        258883..259269
FT                   /codon_start=1
FT                   /gene="AHC2"
FT                   /locus_tag="YCR082W"
FT                   /product="Ahc2p"
FT                   /note="Component of the ADA histone acetyltransferase
FT                   complex; Ahc2p and Ahc1p are unique to the ADA complex and
FT                   not shared with the related SAGA and SLIK complexes; may
FT                   tether Ahc1p to the complex"
FT                   /db_xref="GOA:P25649"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25649"
FT                   /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
FT                   [PMID:14562095]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
FT                   [PMID:14562095]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0005671
FT                   Ada2/Gcn5/Ada3 transcription activator complex
FT                   [PMID:21734642]"
FT                   /experiment="EXISTENCE:physical interaction:GO:0005671
FT                   Ada2/Gcn5/Ada3 transcription activator complex
FT                   [PMID:21734642]"
FT                   /experiment="EXISTENCE:physical interaction:GO:0016573
FT                   histone acetylation [PMID:21734642]"
FT                   /protein_id="DAA07552.1"
FT                   /translation="MITPKGTHDAVAKFQKTDLHQDLDYIVLQQRRTQLETLINERESF
FT                   VKNLCSLFHKIQNTKNYQEFVDVLAENRDLLREIFTVENGFQKQKWISNDDIPQIDWDK
FT                   FALDINAYIAENDQLLALYEDGLL"
FT   gene            259578..259961
FT                   /gene="TRX3"
FT                   /locus_tag="YCR083W"
FT   mRNA            259578..259961
FT                   /gene="TRX3"
FT                   /locus_tag="YCR083W"
FT                   /product="Trx3p"
FT   CDS_pept        259578..259961
FT                   /codon_start=1
FT                   /gene="TRX3"
FT                   /locus_tag="YCR083W"
FT                   /product="Trx3p"
FT                   /note="Mitochondrial thioredoxin; highly conserved
FT                   oxidoreductase required to maintain the redox homeostasis
FT                   of the cell, forms the mitochondrial thioredoxin system
FT                   with Trr2p, redox state is maintained by both Trr2p and
FT                   Glr1p"
FT                   /db_xref="GOA:P25372"
FT                   /db_xref="InterPro:IPR005746"
FT                   /db_xref="InterPro:IPR013766"
FT                   /db_xref="InterPro:IPR017937"
FT                   /db_xref="InterPro:IPR036249"
FT                   /db_xref="PDB:2OE0"
FT                   /db_xref="PDB:2OE1"
FT                   /db_xref="PDB:2OE3"
FT                   /db_xref="PDB:5YKW"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25372"
FT                   /experiment="EXISTENCE:direct assay:GO:0005739
FT                   mitochondrion
FT                   [PMID:10037727|PMID:14576278|PMID:16823961|PMID:24769239]"
FT                   /experiment="EXISTENCE:direct assay:GO:0015036 disulfide
FT                   oxidoreductase activity [PMID:10037727]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0034599 cellular
FT                   response to oxidative stress [PMID:10037727]"
FT                   /protein_id="DAA07553.1"
FT                   /translation="MLFYKPVMRMAVRPLKSIRFQSSYTSITKLTNLTEFRNLIKQNDK
FT                   LVIDFYATWCGPCKMMQPHLTKLIQAYPDVRFVKCDVDESPDIAKECEVTAMPTFVLGK
FT                   DGQLIGKIIGANPTALEKGIKDL"
FT   gene            complement(260311..262452)
FT                   /gene="TUP1"
FT                   /gene_synonym="AAR1"
FT                   /gene_synonym="AER2"
FT                   /gene_synonym="AMM1"
FT                   /gene_synonym="CRT4"
FT                   /gene_synonym="CYC9"
FT                   /gene_synonym="FLK1"
FT                   /gene_synonym="ROX4"
FT                   /gene_synonym="SFL2"
FT                   /gene_synonym="UMR7"
FT                   /locus_tag="YCR084C"
FT   mRNA            complement(260311..262452)
FT                   /gene="TUP1"
FT                   /gene_synonym="AAR1"
FT                   /gene_synonym="AER2"
FT                   /gene_synonym="AMM1"
FT                   /gene_synonym="CRT4"
FT                   /gene_synonym="CYC9"
FT                   /gene_synonym="FLK1"
FT                   /gene_synonym="ROX4"
FT                   /gene_synonym="SFL2"
FT                   /gene_synonym="UMR7"
FT                   /locus_tag="YCR084C"
FT                   /product="chromatin-silencing transcriptional regulator
FT                   TUP1"
FT   CDS_pept        complement(260311..262452)
FT                   /codon_start=1
FT                   /gene="TUP1"
FT                   /gene_synonym="AAR1"
FT                   /gene_synonym="AER2"
FT                   /gene_synonym="AMM1"
FT                   /gene_synonym="CRT4"
FT                   /gene_synonym="CYC9"
FT                   /gene_synonym="FLK1"
FT                   /gene_synonym="ROX4"
FT                   /gene_synonym="SFL2"
FT                   /gene_synonym="UMR7"
FT                   /locus_tag="YCR084C"
FT                   /product="chromatin-silencing transcriptional regulator
FT                   TUP1"
FT                   /note="General repressor of transcription; forms complex
FT                   with Cyc8p, involved in the establishment of repressive
FT                   chromatin structure through interactions with histones H3
FT                   and H4, appears to enhance expression of some genes"
FT                   /db_xref="GOA:P16649"
FT                   /db_xref="InterPro:IPR001680"
FT                   /db_xref="InterPro:IPR013890"
FT                   /db_xref="InterPro:IPR015943"
FT                   /db_xref="InterPro:IPR017986"
FT                   /db_xref="InterPro:IPR019775"
FT                   /db_xref="InterPro:IPR020472"
FT                   /db_xref="InterPro:IPR036322"
FT                   /db_xref="PDB:1ERJ"
FT                   /db_xref="PDB:3VP8"
FT                   /db_xref="PDB:3VP9"
FT                   /db_xref="UniProtKB/Swiss-Prot:P16649"
FT                   /experiment="EXISTENCE:direct assay:GO:0003714
FT                   transcription corepressor activity [PMID:9741624]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
FT                   [PMID:1739976]"
FT                   /experiment="EXISTENCE:direct assay:GO:0016584 nucleosome
FT                   positioning [PMID:15116071]"
FT                   /experiment="EXISTENCE:direct assay:GO:0036033 mediator
FT                   complex binding [PMID:11226276]"
FT                   /experiment="EXISTENCE:direct assay:GO:0042393 histone
FT                   binding [PMID:8675011]"
FT                   /experiment="EXISTENCE:direct assay:GO:0042826 histone
FT                   deacetylase binding [PMID:14525981]"
FT                   /experiment="EXISTENCE:direct assay:GO:0080025
FT                   phosphatidylinositol-3,5-bisphosphate binding
FT                   [PMID:21536737]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000122 negative
FT                   regulation of transcription by RNA polymerase II
FT                   [PMID:1900249|PMID:9858577|PMID:9560430]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000433 carbon
FT                   catabolite repression of transcription from RNA polymerase
FT                   II promoter by glucose [PMID:9461460]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0001198 negative
FT                   regulation of mating-type specific transcription from RNA
FT                   polymerase II promoter [PMID:1312982]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0003714
FT                   transcription corepressor activity [PMID:9741624]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006357
FT                   regulation of transcription by RNA polymerase II
FT                   [PMID:9280286]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0035955 negative
FT                   regulation of dipeptide transport by negative regulation of
FT                   transcription from RNA polymerase II promoter
FT                   [PMID:18708352]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0043486 histone
FT                   exchange [PMID:17387147]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0045944 positive
FT                   regulation of transcription by RNA polymerase II
FT                   [PMID:26546823]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0060256
FT                   regulation of flocculation [PMID:31441971]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:2000217
FT                   regulation of invasive growth in response to glucose
FT                   limitation [PMID:18202364]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:2001020
FT                   regulation of response to DNA damage stimulus
FT                   [PMID:9741624]"
FT                   /experiment="EXISTENCE:physical interaction:GO:0017053
FT                   transcriptional repressor complex [PMID:9111019]"
FT                   /experiment="EXISTENCE:physical interaction:GO:0036033
FT                   mediator complex binding [PMID:11226276]"
FT                   /experiment="EXISTENCE:physical interaction:GO:0042826
FT                   histone deacetylase binding [PMID:14525981]"
FT                   /protein_id="DAA07554.1"
FT                   /translation="MTASVSNTQNKLNELLDAIRQEFLQVSQEANTYRLQNQKDYDFKM
FT                   NQQLAEMQQIRNTVYELELTHRKMKDAYEEEIKHLKLGLEQRDHQIASLTVQQQRQQQQ
FT                   QQQVQQHLQQQQQQLAAASASVPVAQQPPATTSATATPAANTTTGSPSAFPVQASRPNL
FT                   VGSQLPTTTLPVVSSNAQQQLPQQQLQQQQLQQQQPPPQVSVAPLSNTAINGSPTSKET
FT                   TTLPSVKAPESTLKETEPENNNTSKINDTGSATTATTTTATETEIKPKEEDATPASLHQ
FT                   DHYLVPYNQRANHSKPIPPFLLDLDSQSVPDALKKQTNDYYILYNPALPREIDVELHKS
FT                   LDHTSVVCCVKFSNDGEYLATGCNKTTQVYRVSDGSLVARLSDDSAANNHRNSITENNT
FT                   TTSTDNNTMTTTTTTTITTTAMTSAAELAKDVENLNTSSSPSSDLYIRSVCFSPDGKFL
FT                   ATGAEDRLIRIWDIENRKIVMILQGHEQDIYSLDYFPSGDKLVSGSGDRTVRIWDLRTG
FT                   QCSLTLSIEDGVTTVAVSPGDGKYIAAGSLDRAVRVWDSETGFLVERLDSENESGTGHK
FT                   DSVYSVVFTRDGQSVVSGSLDRSVKLWNLQNANNKSDSKTPNSGTCEVTYIGHKDFVLS
FT                   VATTQNDEYILSGSKDRGVLFWDKKSGNPLLMLQGHRNSVISVAVANGSPLGPEYNVFA
FT                   TGSGDCKARIWKYKKIAPN"
FT   gene            262916..263269
FT                   /locus_tag="YCR085W"
FT   mRNA            262916..263269
FT                   /locus_tag="YCR085W"
FT                   /product="hypothetical protein"
FT   CDS_pept        262916..263269
FT                   /codon_start=1
FT                   /locus_tag="YCR085W"
FT                   /product="hypothetical protein"
FT                   /note="hypothetical protein; conserved among S. cerevisiae
FT                   strains; YCR085W is not an essential gene"
FT                   /db_xref="GOA:P25650"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25650"
FT                   /protein_id="DAA80272.1"
FT                   /translation="MLFLYTYVYVFLCTNNDVYNETSVMLSKTSAHCFIAEEVTTDNGL
FT                   ICGLAMLGKTKYQFYELFTVYSIQSLTQLASRVKKGGLIMARLILFTLCALPVLFHFIL
FT                   FMLQYLVFVYIEK"
FT   gene            263392..263964
FT                   /gene="CSM1"
FT                   /locus_tag="YCR086W"
FT   mRNA            263392..263964
FT                   /gene="CSM1"
FT                   /locus_tag="YCR086W"
FT                   /product="Csm1p"
FT   CDS_pept        263392..263964
FT                   /codon_start=1
FT                   /gene="CSM1"
FT                   /locus_tag="YCR086W"
FT                   /product="Csm1p"
FT                   /note="Nucleolar protein that mediates homolog segregation
FT                   during meiosis I; forms a complex with Lrs4p and then Mam1p
FT                   at kinetochores; required for condensin recruitment to the
FT                   replication fork barrier site and rDNA repeat segregation"
FT                   /db_xref="GOA:P25651"
FT                   /db_xref="InterPro:IPR020981"
FT                   /db_xref="InterPro:IPR038608"
FT                   /db_xref="InterPro:IPR040349"
FT                   /db_xref="InterPro:IPR041671"
FT                   /db_xref="PDB:3N4R"
FT                   /db_xref="PDB:3N4S"
FT                   /db_xref="PDB:3N4X"
FT                   /db_xref="PDB:3N7N"
FT                   /db_xref="PDB:5KTB"
FT                   /db_xref="PDB:5V1A"
FT                   /db_xref="PDB:5V3N"
FT                   /db_xref="PDB:6DEI"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25651"
FT                   /experiment="EXISTENCE:direct assay:GO:0005635 nuclear
FT                   envelope [PMID:11489916]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005730 nucleolus
FT                   [PMID:12689592]"
FT                   /experiment="EXISTENCE:direct assay:GO:0033551 monopolin
FT                   complex [PMID:12689592]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0051455
FT                   attachment of spindle microtubules to kinetochore involved
FT                   in homologous chromosome segregation [PMID:12689592]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0034503 protein
FT                   localization to nucleolar rDNA repeats [PMID:19362534]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0045132 meiotic
FT                   chromosome segregation [PMID:11470404]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0045143
FT                   homologous chromosome segregation [PMID:12689592]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0070550 rDNA
FT                   condensation [PMID:18923139]"
FT                   /experiment="EXISTENCE:physical interaction:GO:0045143
FT                   homologous chromosome segregation [PMID:12689592]"
FT                   /protein_id="DAA07555.1"
FT                   /translation="MDPLTVYKNSVKQQIDSADLLVANLVNENFVLSEKLDTKATEIKQ
FT                   LQKQIDSLNAQVKELKTQTSQQAENSEVIKDLYEYLCNVRVHKSYEDDSGLWFDISQGT
FT                   HSGGSSDDYSIMDYKLGFVKGQAQVTEVIYAPVLKQRSTEELYSLQSKLPEYLFETLSF
FT                   PLSSLNQFYNKIAKSLNKKREKKDETE"
FT   gene            complement(264006..264467)
FT                   /locus_tag="YCR087C-A"
FT   mRNA            complement(264006..264467)
FT                   /locus_tag="YCR087C-A"
FT                   /product="hypothetical protein"
FT   CDS_pept        complement(264006..264467)
FT                   /codon_start=1
FT                   /locus_tag="YCR087C-A"
FT                   /product="hypothetical protein"
FT                   /note="hypothetical protein; green fluorescent protein
FT                   (GFP)-fusion protein localizes to the nucleolus; YCR087C-A
FT                   is not an essential gene"
FT                   /db_xref="GOA:P37263"
FT                   /db_xref="InterPro:IPR013087"
FT                   /db_xref="InterPro:IPR014898"
FT                   /db_xref="InterPro:IPR036236"
FT                   /db_xref="InterPro:IPR039999"
FT                   /db_xref="UniProtKB/Swiss-Prot:P37263"
FT                   /experiment="EXISTENCE:direct assay:GO:0005730 nucleolus
FT                   [PMID:14562095]"
FT                   /protein_id="DAA07556.1"
FT                   /translation="MVTFNCEVCNDTVPKKNTEKHYYRCPNAYYTCIDCSKTFEDGVSY
FT                   KNHTSCISEDEKYQKALYKGNKKQKQKQQQKQQQKQHQHQPVATPAKKVEKPVIKKAEK
FT                   VEKTSNGIELHKGKSLYKILKTMKDKGAKKTFLKSLVVDSEGQIRYAKE"
FT   gene            265068..266846
FT                   /gene="ABP1"
FT                   /locus_tag="YCR088W"
FT   mRNA            265068..266846
FT                   /gene="ABP1"
FT                   /locus_tag="YCR088W"
FT                   /product="Abp1p"
FT   CDS_pept        265068..266846
FT                   /codon_start=1
FT                   /gene="ABP1"
FT                   /locus_tag="YCR088W"
FT                   /product="Abp1p"
FT                   /note="Actin-binding protein of the cortical actin
FT                   cytoskeleton; important for activation of actin nucleation
FT                   mediated by the Arp2/Arp3 complex; inhibits actin filament
FT                   elongation at the barbed-end; phosphorylation within its
FT                   proline-rich region, mediated by Cdc28p and Pho85p,
FT                   protects Abp1p from PEST sequence-mediated proteolysis;
FT                   mammalian homolog of HIP-55 (hematopoietic progenitor
FT                   kinase 1 [HPK1]-interacting protein of 55 kDa)"
FT                   /db_xref="GOA:P15891"
FT                   /db_xref="InterPro:IPR001452"
FT                   /db_xref="InterPro:IPR002108"
FT                   /db_xref="InterPro:IPR029006"
FT                   /db_xref="InterPro:IPR035718"
FT                   /db_xref="InterPro:IPR036028"
FT                   /db_xref="PDB:1HQZ"
FT                   /db_xref="PDB:1JO8"
FT                   /db_xref="PDB:2K3B"
FT                   /db_xref="PDB:2RPN"
FT                   /db_xref="UniProtKB/Swiss-Prot:P15891"
FT                   /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
FT                   [PMID:11914276]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005938 cell cortex
FT                   [PMID:11950888]"
FT                   /experiment="EXISTENCE:direct assay:GO:0030479 actin
FT                   cortical patch [PMID:3060468|PMID:8163554|PMID:16824951]"
FT                   /experiment="EXISTENCE:direct assay:GO:0043332 mating
FT                   projection tip [PMID:19053807]"
FT                   /experiment="EXISTENCE:direct assay:GO:0051015 actin
FT                   filament binding [PMID:3060468]"
FT                   /experiment="EXISTENCE:direct assay:GO:2000601 positive
FT                   regulation of Arp2/3 complex-mediated actin nucleation
FT                   [PMID:16824951]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000147 actin
FT                   cortical patch assembly [PMID:18177206]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0044379 protein
FT                   localization to actin cortical patch
FT                   [PMID:10087264|PMID:11668184|PMID:15798181]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0051016
FT                   barbed-end actin filament capping [PMID:23333351]"
FT                   /protein_id="DAA07557.1"
FT                   /translation="MALEPIDYTTHSREIDAEYLKIVRGSDPDTTWLIISPNAKKEYEP
FT                   ESTGSSFHDFLQLFDETKVQYGLARVSPPGSDVEKIIIIGWCPDSAPLKTRASFAANFA
FT                   AVANNLFKGYHVQVTARDEDDLDENELLMKISNAAGARYSIQTSSKQQGKASTPPVKKS
FT                   FTPSKSPAPVSKKEPVKTPSPAPAAKISSRVNDNNDDDDWNEPELKERDFDQAPLKPNQ
FT                   SSYKPIGKIDLQKVIAEEKAKEDPRLVQKPTAAGSKIDPSSDIANLKNESKLKRDSEFN
FT                   SFLGTTKPPSMTESSLKNDDDKVIKGFRNEKSPAQLWAERKAKQNSGNAETKAEAPKPE
FT                   VPEDEPEGEPDVKDLKSKFEGLAASEKEEEEMENKFAPPPKKSEPTIISPKPFSKPQEP
FT                   VKAEEAEQPKTDYKKIGNPLPGMHIEADNEEEPEENDDDWDDDEDEAAQPPLPSRNVAS
FT                   GAPVQKEEPEQEEIAPSLPSRNSIPAPKQEEAPEQAPEEEIEEEAEEAAPQLPSRSSAA
FT                   PPPPPRRATPEKKPKENPWATAEYDYDAAEDNELTFVENDKIINIEFVDDDWWLGELEK
FT                   DGSKGLFPSNYVSLGN"
FT   gene            267434..272263
FT                   /gene="FIG2"
FT                   /locus_tag="YCR089W"
FT   mRNA            267434..272263
FT                   /gene="FIG2"
FT                   /locus_tag="YCR089W"
FT                   /product="Fig2p"
FT   CDS_pept        267434..272263
FT                   /codon_start=1
FT                   /gene="FIG2"
FT                   /locus_tag="YCR089W"
FT                   /product="Fig2p"
FT                   /note="Cell wall adhesin, expressed specifically during
FT                   mating; may be involved in maintenance of cell wall
FT                   integrity during mating; FIG2 has a paralog, AGA1, that
FT                   arose from the whole genome duplication"
FT                   /db_xref="GOA:P25653"
FT                   /db_xref="InterPro:IPR025928"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25653"
FT                   /experiment="EXISTENCE:direct assay:GO:0005937 mating
FT                   projection [PMID:11027318]"
FT                   /experiment="EXISTENCE:direct assay:GO:0009277 fungal-type
FT                   cell wall [PMID:9456310]"
FT                   /experiment="EXISTENCE:direct assay:GO:0071944 cell
FT                   periphery [PMID:26928762]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000753 cell
FT                   morphogenesis involved in conjugation with cellular fusion
FT                   [PMID:9456310]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000755 cytogamy
FT                   [PMID:9456310]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0001403 invasive
FT                   growth in response to glucose limitation [PMID:11027318]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0044182
FT                   filamentous growth of a population of unicellular organisms
FT                   [PMID:11027318]"
FT                   /protein_id="DAA07558.1"
FT                   /translation="MNSFASLGLIYSVVNLLTRVEAQIVFYQNSSTSLPVPTLVSTSIA
FT                   DFHESSSTGEVQYSSSYSYVQPSIDSFTSSSFLTSFEAPTETSSSYAVSSSLITSDTFS
FT                   SYSDIFDEETSSLISTSAASSEKASSTLSSTAQPHRTSHSSSSFELPVTAPSSSSLPSS
FT                   TSLTFTSVNPSQSWTSFNSEKSSALSSTIDFTSSEISGSTSPKSLESFDTTGTITSSYS
FT                   PSPSSKNSNQTSLLSPLEPLSSSSGDLILSSTIQATTNDQTSKTIPTLVDATSSLPPTL
FT                   RSSSMAPTSGSDSISHNFTSPPSKTSGNYDVLTSNSIDPSLFTTTSEYSSTQLSSLNRA
FT                   SKSETVNFTASIASTPFGTDSATSLIDPISSVGSTASSFVGISTANFSTQGNSNYVPES
FT                   TASGSSQYQDWSSSSLPLSQTTWVVINTTNTQGSVTSTTSPAYVSTATKTVDGVITEYV
FT                   TWCPLTQTKSQAIGVSSSISSVPQASSFSGSSILSSNSSTLAASNNVPESTASGSSQYQ
FT                   DWSSSSLPLSQTTWVVINTTNTQGSVTSTTSPAYVSTATKTVDGVITEYVTWCPLTQTK
FT                   SQAIGISSSTISATQTSKPSSILTLGISTLQLSDATFKGTETINTHLMTESTSITEPTY
FT                   FSGTSDSFYLCTSEVNLASSLSSYPNFSSSEGSTATITNSTVTFGSTSKYPSTSVSNPT
FT                   EASQHVSSSVNSLTDFTSNSTETIAVISNIHKTSSNKDYSLTTTQLKTSGMQTLVLSTV
FT                   TTTVNGAATEYTTWCPASSIAYTTSISYKTLVLTTEVCSHSECTPTVITSVTATSSTIP
FT                   LLSTSSSTVLSSTVSEGAKNPAASEVTINTQVSATSEATSTSTQVSATSATATASESST
FT                   TSQVSTASETISTLGTQNFTTTGSLLFPALSTEMINTTVVSRKTLIISTEVCSHSKCVP
FT                   TVITEVVTSKGTPSNGHSSQTLQTEAVEVTLSSHQTVTMSTEVCSNSICTPTVITSVQM
FT                   RSTPFPYLTSSTSSSSLASTKKSSLEASSEMSTFSVSTQSLPLAFTSSEKRSTTSVSQW
FT                   SNTVLTNTIMSSSSNVISTNEKPSSTTSPYNFSSGYSLPSSSTPSQYSLSTATTTINGI
FT                   KTVYTTWCPLAEKSTVAASSQSSRSVDRFVSSSKPSSSLSQTSIQYTLSTATTTISGLK
FT                   TVYTTWCPLTSKSTLGATTQTSSTAKVRITSASSATSTSISLSTSTESESSSGYLSKGV
FT                   CSGTECTQDVPTQSSSPASTLAYSPSVSTSSSSSFSTTTASTLTSTHTSVPLLPSSSSI
FT                   SASSPSSTSLLSTSLPSPAFTSSTLPTATAVSSSTFIASSLPLSSKSSLSLSPVSSSIL
FT                   MSQFSSSSSSSSSLASLPSLSISPTVDTVSVLQPTTSIATLTCTDSQCQQEVSTICNGS
FT                   NCDDVTSTATTPPSTVTDTMTCTGSECQKTTSSSCDGYSCKVSETYKSSATISACSGEG
FT                   CQASATSELNSQYVTMTSVITPSAITTTSVEVHSTESTISITTVKPVTYTSSDTNGELI
FT                   TITSSSQTVIPSVTTIITRTKVAITSAPKPTTTTYVEQRLSSSGIATSFVAAASSTWIT
FT                   TPIVSTYAGSASKFLCSKFFMIMVMVINFI"
FT   gene            complement(272315..272863)
FT                   /locus_tag="YCR090C"
FT   mRNA            complement(272315..272863)
FT                   /locus_tag="YCR090C"
FT                   /product="hypothetical protein"
FT   CDS_pept        complement(272315..272863)
FT                   /codon_start=1
FT                   /locus_tag="YCR090C"
FT                   /product="hypothetical protein"
FT                   /note="hypothetical protein; green fluorescent protein
FT                   (GFP)-fusion protein localizes to the cytoplasm and
FT                   nucleus; YCR090C is not an essential gene"
FT                   /db_xref="GOA:P25654"
FT                   /db_xref="InterPro:IPR008584"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25654"
FT                   /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
FT                   [PMID:14562095]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
FT                   [PMID:14562095]"
FT                   /protein_id="DAA07559.1"
FT                   /translation="MPLFLVLKATLSENVTKVSIENTNESRAEFAFDLQCTSCRELHDS
FT                   KVIINTFEEYAMPASKGTASFLMKCKFCSKELSVNLCAFEDEYLTDQSDDKWAKIKDVR
FT                   KKHGLSKVKEDSFIPLSLDCRGCELIKFYPDTITFEVSLSSGKVMSCQLEDNEWYDYDD
FT                   NLGEEVTMTDFSSSIIKGK"
FT   rep_origin      272852..273095
FT                   /note="ARS316; Inefficient autonomously replicating
FT                   sequence; active in 25% of cell cycles"
FT   gene            274404..276566
FT                   /gene="KIN82"
FT                   /gene_synonym="FPK2"
FT                   /locus_tag="YCR091W"
FT   mRNA            274404..276566
FT                   /gene="KIN82"
FT                   /gene_synonym="FPK2"
FT                   /locus_tag="YCR091W"
FT                   /product="putative serine/threonine protein kinase KIN82"
FT   CDS_pept        274404..276566
FT                   /codon_start=1
FT                   /gene="KIN82"
FT                   /gene_synonym="FPK2"
FT                   /locus_tag="YCR091W"
FT                   /product="putative serine/threonine protein kinase KIN82"
FT                   /EC_number="2.7.11.1"
FT                   /note="Putative serine/threonine protein kinase; implicated
FT                   in the regulation of phospholipid asymmetry through the
FT                   activation of phospholipid translocases (flippases);
FT                   involved in the phosphorylation of upstream inhibitory
FT                   kinase Ypk1p along with Fpk1p; has a redundant role in the
FT                   cellular response to mating pheromone; KIN82 has a paralog,
FT                   FPK1, that arose from the whole genome duplication"
FT                   /db_xref="GOA:P25341"
FT                   /db_xref="InterPro:IPR000719"
FT                   /db_xref="InterPro:IPR008271"
FT                   /db_xref="InterPro:IPR011009"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25341"
FT                   /experiment="EXISTENCE:direct assay:GO:0004672 protein
FT                   kinase activity [PMID:16319894]"
FT                   /experiment="EXISTENCE:direct assay:GO:0006468 protein
FT                   phosphorylation [PMID:16319894]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0000749
FT                   response to pheromone triggering conjugation with cellular
FT                   fusion [PMID:25378585]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0006468
FT                   protein phosphorylation [PMID:19966303]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0045332
FT                   phospholipid translocation [PMID:18199685]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000749 response
FT                   to pheromone triggering conjugation with cellular fusion
FT                   [PMID:11337509]"
FT                   /protein_id="DAA07560.2"
FT                   /translation="MTQQEYRSPSQRLSKGRSMSLPKIFARNLRSLQNNAPPGKNINVN
FT                   CLNVNSCSLSASPSSQINMACNGNKQDLPIPFPLHVECNDSWSSSKLNKFKSMFNHNRS
FT                   KSSGTTDASTSEKGTHKREPRSTIHTELLQSSIIGEPNVHSTTSSTLIPNEAICSTPNE
FT                   ISGSSSPDAELFTFDMPTDPSSFHTPSSPSYIAKDSRNLSNGSLNDINENEELQNFHRK
FT                   ISENGSASPLANLSLSNSPIDSPRKNSETRKDQIPMNITPRLRRAASEPFNTAKDGLMR
FT                   EDYIALKQPPSLGDIVEPRRSRRLRTKSFGNKFQDITVEPQSFEKIRLLGQGDVGKVYL
FT                   VRERDTNQIFALKVLNKHEMIKRKKIKRVLTEQEILATSDHPFIVTLYHSFQTKDYLYL
FT                   CMEYCMGGEFFRALQTRKSKCIAEEDAKFYASEVVAALEYLHLLGFIYRDLKPENILLH
FT                   QSGHVMLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGFRTNSFVGTEEYLAPEVIRGN
FT                   GHTAAVDWWTLGILIYEMLFGCTPFKGDNSNETFSNILTKDVKFPHDKEVSKNCKDLIK
FT                   KLLNKNEAKRLGSKSGAADIKRHPFFKKVQWSFLRNQDPPLIPALNDNGCELPFILSCN
FT                   KHPKRNSVSEQETKMFCEKVANDDEIDEADPFHDFNSMSLTKKDHNILTYSENYTYGKI
FT                   LYKATCTRPRHNSSHRSFFKDIIPEL"
FT   gene            complement(276764..279820)
FT                   /gene="MSH3"
FT                   /locus_tag="YCR092C"
FT   mRNA            complement(276764..279820)
FT                   /gene="MSH3"
FT                   /locus_tag="YCR092C"
FT                   /product="mismatch repair protein MSH3"
FT   CDS_pept        complement(276764..279820)
FT                   /codon_start=1
FT                   /gene="MSH3"
FT                   /locus_tag="YCR092C"
FT                   /product="mismatch repair protein MSH3"
FT                   /note="Mismatch repair protein; forms dimers with Msh2p
FT                   that mediate repair of insertion or deletion mutations and
FT                   removal of nonhomologous DNA ends, contains a PCNA (Pol30p)
FT                   binding motif required for genome stability"
FT                   /db_xref="GOA:P25336"
FT                   /db_xref="InterPro:IPR000432"
FT                   /db_xref="InterPro:IPR007695"
FT                   /db_xref="InterPro:IPR007696"
FT                   /db_xref="InterPro:IPR007860"
FT                   /db_xref="InterPro:IPR007861"
FT                   /db_xref="InterPro:IPR016151"
FT                   /db_xref="InterPro:IPR017261"
FT                   /db_xref="InterPro:IPR027417"
FT                   /db_xref="InterPro:IPR036187"
FT                   /db_xref="InterPro:IPR036678"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25336"
FT                   /experiment="EXISTENCE:direct assay:GO:0000403 Y-form DNA
FT                   binding [PMID:16781730]"
FT                   /experiment="EXISTENCE:direct assay:GO:0000404 heteroduplex
FT                   DNA loop binding [PMID:16781730]"
FT                   /experiment="EXISTENCE:direct assay:GO:0000406
FT                   double-strand/single-strand DNA junction binding
FT                   [PMID:16781730]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
FT                   [PMID:14562095]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
FT                   [PMID:14562095]"
FT                   /experiment="EXISTENCE:direct assay:GO:0030983 mismatched
FT                   DNA binding [PMID:17636021]"
FT                   /experiment="EXISTENCE:direct assay:GO:0032135 DNA
FT                   insertion or deletion binding [PMID:8805366]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0000735
FT                   removal of nonhomologous ends [PMID:9256462]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000710 meiotic
FT                   mismatch repair [PMID:16702432]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000735 removal
FT                   of nonhomologous ends [PMID:9256462]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006298 mismatch
FT                   repair [PMID:8510668|PMID:9520271]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006310 DNA
FT                   recombination [PMID:15920474]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006312 mitotic
FT                   recombination [PMID:8849883]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0043111
FT                   replication fork arrest [PMID:27045900]"
FT                   /experiment="EXISTENCE:physical interaction:GO:0032302
FT                   MutSbeta complex [PMID:8805366]"
FT                   /protein_id="DAA07561.1"
FT                   /translation="MAGQPTISRFFKKAVKSELTHKQEQEVAVGNGAGSESICLDTDEE
FT                   DNLSSVASTTVTNDSFPLKGSVSSKNSKNSEKTSGTSTTFNDIDFAKKLDRIMKRRSDE
FT                   NVEAEDDEEEGEEDFVKKKARKSPTAKLTPLDKQVKDLKMHHRDKVLVIRVGYKYKCFA
FT                   EDAVTVSRILHIKLVPGKLTIDESNPQDCNHRQFAYCSFPDVRLNVHLERLVHHNLKVA
FT                   VVEQAETSAIKKHDPGASKSSVFERKISNVFTKATFGVNSTFVLRGKRILGDTNSIWAL
FT                   SRDVHQGKVAKYSLISVNLNNGEVVYDEFEEPNLADEKLQIRIKYLQPIEVLVNTDDLP
FT                   LHVAKFFKDISCPLIHKQEYDLEDHVVQAIKVMNEKIQLSPSLIRLVSKLYSHMVEYNN
FT                   EQVMLIPSIYSPFASKIHMLLDPNSLQSLDIFTHDGGKGSLFWLLDHTRTSFGLRMLRE
FT                   WILKPLVDVHQIEERLDAIECITSEINNSIFFESLNQMLNHTPDLLRTLNRIMYGTTSR
FT                   KEVYFYLKQITSFVDHFKMHQSYLSEHFKSSDGRIGKQSPLLFRLFSELNELLSTTQLP
FT                   HFLTMINVSAVMEKNSDKQVMDFFNLNNYDCSEGIIKIQRESESVRSQLKEELAEIRKY
FT                   LKRPYLNFRDEVDYLIEVKNSQIKDLPDDWIKVNNTKMVSRFTTPRTQKLTQKLEYYKD
FT                   LLIRESELQYKEFLNKITAEYTELRKITLNLAQYDCILSLAATSCNVNYVRPTFVNGQQ
FT                   AIIAKNARNPIIESLDVHYVPNDIMMSPENGKINIITGPNMGGKSSYIRQVALLTIMAQ
FT                   IGSFVPAEEIRLSIFENVLTRIGAHDDIINGDSTFKVEMLDILHILKNCNKRSLLLLDE
FT                   VGRGTGTHDGIAISYALIKYFSELSDCPLILFTTHFPMLGEIKSPLIRNYHMDYVEEQK
FT                   TGEDWMSVIFLYKLKKGLTYNSYGMNVAKLARLDKDIINRAFSISEELRKESINEDALK
FT                   LFSSLKRILKSDNITATDKLAKLLSLDIH"
FT   gene            280117..286443
FT                   /gene="CDC39"
FT                   /gene_synonym="NOT1"
FT                   /gene_synonym="ROS1"
FT                   /gene_synonym="SMD6"
FT                   /locus_tag="YCR093W"
FT   mRNA            280117..286443
FT                   /gene="CDC39"
FT                   /gene_synonym="NOT1"
FT                   /gene_synonym="ROS1"
FT                   /gene_synonym="SMD6"
FT                   /locus_tag="YCR093W"
FT                   /product="CCR4-NOT core subunit CDC39"
FT   CDS_pept        280117..286443
FT                   /codon_start=1
FT                   /gene="CDC39"
FT                   /gene_synonym="NOT1"
FT                   /gene_synonym="ROS1"
FT                   /gene_synonym="SMD6"
FT                   /locus_tag="YCR093W"
FT                   /product="CCR4-NOT core subunit CDC39"
FT                   /note="Subunit of the CCR4-NOT1 core complex; this complex
FT                   has multiple roles in the regulation of mRNA levels
FT                   including regulation of transcription and destabilization
FT                   of mRNA by deadenylation; basal transcription factor that
FT                   increases initiation and elongation; activates the ATPase
FT                   activity of Dhh1p, resulting in processing body
FT                   disassembly"
FT                   /db_xref="GOA:P25655"
FT                   /db_xref="InterPro:IPR007196"
FT                   /db_xref="InterPro:IPR016021"
FT                   /db_xref="InterPro:IPR024557"
FT                   /db_xref="InterPro:IPR032191"
FT                   /db_xref="InterPro:IPR032193"
FT                   /db_xref="InterPro:IPR032194"
FT                   /db_xref="InterPro:IPR032195"
FT                   /db_xref="InterPro:IPR038535"
FT                   /db_xref="InterPro:IPR040398"
FT                   /db_xref="PDB:4B89"
FT                   /db_xref="PDB:4B8A"
FT                   /db_xref="PDB:4B8B"
FT                   /db_xref="PDB:4B8C"
FT                   /db_xref="PDB:4CV5"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25655"
FT                   /experiment="EXISTENCE:direct assay:GO:0000288
FT                   nuclear-transcribed mRNA catabolic process,
FT                   deadenylation-dependent decay [PMID:11889048]"
FT                   /experiment="EXISTENCE:direct assay:GO:0000289
FT                   nuclear-transcribed mRNA poly(A) tail shortening
FT                   [PMID:11889048]"
FT                   /experiment="EXISTENCE:direct assay:GO:0001671 ATPase
FT                   activator activity [PMID:27692063]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
FT                   [PMID:7926748]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
FT                   [PMID:11889048]"
FT                   /experiment="EXISTENCE:direct assay:GO:0010607 negative
FT                   regulation of cytoplasmic mRNA processing body assembly
FT                   [PMID:27692063]"
FT                   /experiment="EXISTENCE:direct assay:GO:0032968 positive
FT                   regulation of transcription elongation from RNA polymerase
FT                   II promoter [PMID:21406554]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0006368
FT                   transcription elongation from RNA polymerase II promoter
FT                   [PMID:11404327]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000288
FT                   nuclear-transcribed mRNA catabolic process,
FT                   deadenylation-dependent decay [PMID:11889048]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0000749 response
FT                   to pheromone triggering conjugation with cellular fusion
FT                   [PMID:2099190]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006368
FT                   transcription elongation from RNA polymerase II promoter
FT                   [PMID:11404327]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0007124
FT                   pseudohyphal growth [PMID:9055077]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0010607 negative
FT                   regulation of cytoplasmic mRNA processing body assembly
FT                   [PMID:27692063]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0051726
FT                   regulation of cell cycle [PMID:2680756]"
FT                   /experiment="EXISTENCE:physical interaction:GO:0006357
FT                   regulation of transcription by RNA polymerase II
FT                   [PMID:10490603]"
FT                   /experiment="EXISTENCE:physical interaction:GO:0030015
FT                   CCR4-NOT core complex [PMID:10490603]"
FT                   /protein_id="DAA07562.1"
FT                   /translation="MLSATYRDLNTASNLETSKEKQAAQIVIAQISLLFTTLNNDNFES
FT                   VEREIRHILDRSSVDIYIKVWERLLTLSSRDILQAGKFLLQENLLHRLLLEFAKDLPKK
FT                   STDLIELLKERTFNNQEFQKQTGITLSLFIDLFDKSANKDIIESLDRSSQINDFKTIKM
FT                   NHTNYLRNFFLQTTPETLESNLRDLLHSLEGESLNDLLALLLSEILSPGSQNLQNDPTR
FT                   SWLTPPMVLDATNRGNVIARSISSLQANQINWNRVFNLMSTKYFLSAPLMPTTASLSCL
FT                   FAALHDGPVIDEFFSCDWKVIFKLDLAIQLHKWSVQNGCFDLLNAEGTRKVSETIPNTK
FT                   QSLLYLLSIASLNLELFLQREELSDGPMLAYFQECFFEDFNYAPEYLILALVKEMKRFV
FT                   LLIENRTVIDEILITLLIQVHNKSPSSFKDVISTITDDSKIVDAAKIIINSDDAPIANF
FT                   LKSLLDTGRLDTVINKLPFNEAFKILPCARQIGWEGFDTFLKTKVSPSNVDVVLESLEV
FT                   QTKMTDTNTPFRSLKTFDLFAFHSLIEVLNKCPLDVLQLQRFESLEFSLLIAFPRLINF
FT                   GFGHDEAILANGDIAGINNDIEKEMQNYLQKMYSGELAIKDVIELLRRLRDSDLPRDQE
FT                   VFTCITHAVIAESTFFQDYPLDALATTSVLFGSMILFQLLRGFVLDVAFRIIMRFAKEP
FT                   PESKMFKFAVQAIYAFRIRLAEYPQYCKDLLRDVPALKSQAQVYQSIVEAATLANAPKE
FT                   RSRPVQEMIPLKFFAVDEVSCQINQEGAPKDVVEKVLFVLNNVTLANLNNKVDELKKSL
FT                   TPNYFSWFSTYLVTQRAKTEPNYHDLYSKVIVAMGSGLLHQFMVNVTLRQLFVLLSTKD
FT                   EQAIDKKHLKNLASWLGCITLALNKPIKHKNIAFREMLIEAYKENRLEIVVPFVTKILQ
FT                   RASESKIFKPPNPWTVGILKLLIELNEKANWKLSLTFEVEVLLKSFNLTTKSLKPSNFI
FT                   NTPEVIETLSGALGSITLEQQQTEQQRQIILMQQHQQQMLIYQQRQQQQQQRQQQQQHH
FT                   ISANTIADQQAAFGGEGSISHDNPFNNLLGSTIFVTHPDLKRVFQMALAKSVREILLEV
FT                   VEKSSGIAVVTTTKIILKDFATEVDESKLKTAAIIMVRHLAQSLARATSIEPLKEGIRS
FT                   TMQSLAPNLMSLSSSPAEELDTAINENIGIALVLIEKASMDKSTQDLADQLMQAIAIRR
FT                   YHKERRADQPFITQNTNPYSLSLPEPLGLKNTGVTPQQFRVYEEFGKNIPNLDVIPFAG
FT                   LPAHAPPMTQNVGLTQPQQQQAQMPTQILTSEQIRAQQQQQQLQKSRLNQPSQSAQPPG
FT                   VNVPNPQGGIAAVQSDLEQNQRVLVHLMDILVSQIKENATKNNLAELGDQNQIKTIIFQ
FT                   ILTFIAKSAQKDQLALKVSQAVVNSLFATSESPLCREVLSLLLEKLCSLSLVARKDVVW
FT                   WLVYALDSRKFNVPVIRSLLEVNLIDATELDNVLVTAMKNKMENSTEFAMKLIQNTVLS
FT                   DDPILMRMDFIKTLEHLASSEDENVKKFIKEFEDTKIMPVRKGTKTTRTEKLYLVFTEW
FT                   VKLLQRVENNDVITTVFIKQLVEKGVISDTDNLLTFVKSSLELSVSSFKESDPTDEVFI
FT                   AIDALGSLIIKLLILQGFKDDTRRDYINAIFSVIVLVFAKDHSQEGTTFNERPYFRLFS
FT                   NILYEWATIRTHNFVRISDSSTRQELIEFDSVFYNTFSGYLHALQPFAFPGFSFAWVTL
FT                   LSHRMLLPIMLRLPNKIGWEKLMLLIIDLFKFLDQYTSKHAVSDAVSVVYKGTLRVILG
FT                   ISNDMPSFLIENHYELMNNLPPTYFQLKNVILSAIPKNMTVPNPYDVDLNMEDIPACKE
FT                   LPEVFFDPVIDLHSLKKPVDNYLRIPSNSLLRTILSAIYKDTYDIKKGVGYDFLSVDSK
FT                   LIRAIVLHVGIEAGIEYKRTSSNAVFNTKSSYYTLLFNLIQNGSIEMKYQIILSIVEQL
FT                   RYPNIHTYWFSFVLMNMFKSDEWNDQKLEVQEIILRNFLKRIIVNKPHTWGVSVFFTQL
FT                   INNNDINLLDLPFVQSVPEIKLILQQLVKYSKKYTTSEQDDQSATINRRQTPLQSNA"
FT   gene            286762..287937
FT                   /gene="CDC50"
FT                   /locus_tag="YCR094W"
FT   mRNA            286762..287937
FT                   /gene="CDC50"
FT                   /locus_tag="YCR094W"
FT                   /product="aminophospholipid translocase regulatory protein
FT                   CDC50"
FT   CDS_pept        286762..287937
FT                   /codon_start=1
FT                   /gene="CDC50"
FT                   /locus_tag="YCR094W"
FT                   /product="aminophospholipid translocase regulatory protein
FT                   CDC50"
FT                   /note="Endosomal protein that interacts with phospholipid
FT                   flippase Drs2p; interaction with Cdc50p is essential for
FT                   Drs2p catalytic activity; mutations affect cell polarity
FT                   and polarized growth; similar to Lem3p; CDC50 has a
FT                   paralog, YNR048W, that arose from the whole genome
FT                   duplication"
FT                   /db_xref="GOA:P25656"
FT                   /db_xref="InterPro:IPR005045"
FT                   /db_xref="PDB:6ROH"
FT                   /db_xref="PDB:6ROI"
FT                   /db_xref="PDB:6ROJ"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25656"
FT                   /experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
FT                   reticulum [PMID:26928762]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005802 trans-Golgi
FT                   network [PMID:15090616]"
FT                   /experiment="EXISTENCE:direct assay:GO:0031902 late
FT                   endosome membrane [PMID:12589066]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0006897
FT                   endocytosis [PMID:16195350]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0015247
FT                   aminophospholipid flippase activity [PMID:15090616]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0045332
FT                   phospholipid translocation [PMID:15090616]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0051666 actin
FT                   cortical patch localization [PMID:16195350]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0006886
FT                   intracellular protein transport [PMID:16956384]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0042147
FT                   retrograde transport, endosome to Golgi [PMID:28057802]"
FT                   /experiment="EXISTENCE:physical interaction:GO:1990530
FT                   Cdc50p-Drs2p complex [PMID:15090616]"
FT                   /protein_id="DAA07563.1"
FT                   /translation="MVSLFKRGKAPPLTKEGPTSKKPPNTAFRQQRLKAWQPILSPQSV
FT                   LPLLIFVACIFTPIGIGLIVSATKVQDLTIDYSHCDTKASTTAFEDIPKKYIKYHFKSK
FT                   VENKPQWRLTENENGEQSCELQFEIPNDIKKSIFIYYKITNFYQNHRRYVQSFDTKQIL
FT                   GEPIKKDDLDTSCSPIRSREDKIIYPCGLIANSMFNDTFSQVLSGIDDTEDYNLTNKHI
FT                   SWSIDRHRFKTTKYNASDIVPPPNWMKKYPDGYTDENLPDIHTWEEFQVWMRTAAFPKF
FT                   YKLTLKNESASLPKGKYQMNIELNYPISLFGGTKSFVLTTNGAIGGRNMSLGVLYLIVA
FT                   GLCALFGIIFLVKLIFQPRAMGDHTYLNFDDEENEDYEDVHAENTTLREIL"
FT   gene            complement(288170..289258)
FT                   /gene="OCA4"
FT                   /locus_tag="YCR095C"
FT   mRNA            complement(288170..289258)
FT                   /gene="OCA4"
FT                   /locus_tag="YCR095C"
FT                   /product="Oca4p"
FT   CDS_pept        complement(288170..289258)
FT                   /codon_start=1
FT                   /gene="OCA4"
FT                   /locus_tag="YCR095C"
FT                   /product="Oca4p"
FT                   /note="Cytoplasmic protein required for replication of
FT                   Brome mosaic virus; S. cerevisiae is a model system for
FT                   studying replication of positive-strand RNA viruses in
FT                   their natural hosts"
FT                   /db_xref="GOA:P25366"
FT                   /db_xref="InterPro:IPR004861"
FT                   /db_xref="InterPro:IPR029021"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25366"
FT                   /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
FT                   [PMID:14562095]"
FT                   /protein_id="DAA07564.1"
FT                   /translation="MLVPPANFGIAEEGIYRCSKVETLNLSFLETLNLKTAIFIGGQEP
FT                   SKFFKDFFTRSSIKWIVLRMSDFSAAAVPVKSSSVSNANLYSNNNSTLSLQEEKKKSTA
FT                   NGSQNSTTGDPVIQEELAYHLTDNDDLMLIKSTCLKRTFKTLLNVDNYNVLLVDKTALV
FT                   IGILRKIQKWNIASIINEYRLFSGKNRNYFAETFLEIINIEIEQEKDNKTIVDNKAKKL
FT                   PLENNRTHSIEYKANSGKLIRVNEDDLCREPEVPQRLLTLINQIETKVKNNKVLQVSGV
FT                   LGDDLKKTSSDLGIFGHRYRLAFNKKENGDYGYYKARGKDNVKIRIPCDSELPDWFRFQ
FT                   RDLWEKENVPEEHHFYREHIFT"
FT   gene            289639..289797
FT                   /locus_tag="YCR095W-A"
FT   mRNA            289639..289797
FT                   /locus_tag="YCR095W-A"
FT                   /product="hypothetical protein"
FT   CDS_pept        289639..289797
FT                   /codon_start=1
FT                   /locus_tag="YCR095W-A"
FT                   /product="hypothetical protein"
FT                   /db_xref="EnsemblGenomes-Gn:YCR095W-A"
FT                   /db_xref="EnsemblGenomes-Tr:YCR095W-A"
FT                   /db_xref="GOA:Q3E787"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q3E787"
FT                   /protein_id="DAA07565.1"
FT                   /translation="MTVLIKLGLRILHVYKGFFRKVILKYFFFSSEHTKVNKKSSMHAF
FT                   LCKIYKR"
FT   repeat_region   291373..291712
FT                   /rpt_type=LONG_TERMINAL_REPEAT
FT                   /note="Ty1 LTR"
FT   repeat_region   291922..292167
FT                   /rpt_type=LONG_TERMINAL_REPEAT
FT                   /note="Ty5 LTR"
FT   misc_feature    292388..295034
FT                   /note="HMR; Mating-type cassette - right; unexpressed
FT                   complete copy of the mating-type genes, silenced by the
FT                   Sir2 histone deacetylase and its associated SIR1, SIR3 and
FT                   SIR4 proteins; mating-type switching involves replacement
FT                   of the Ya or Yalpha sequences present at the MAT locus with
FT                   either the a or alpha genes located at one of the HM loci
FT                   in a process stimulated by the HO endonuclease; sequence
FT                   replacement occurs by gene conversion, leaving the donor
FT                   unaltered"
FT   rep_origin      292638..292694
FT                   /note="ARS317; ARS that fires extremely inefficiently and
FT                   late during S phase; fires late and inefficiently compared
FT                   to other origins in the genome; active in only a small
FT                   fraction of cell cycles"
FT   gene            complement(293179..293538)
FT                   /gene="HMRA2"
FT                   /gene_synonym="A2"
FT                   /locus_tag="YCR096C"
FT   mRNA            complement(293179..293538)
FT                   /gene="HMRA2"
FT                   /gene_synonym="A2"
FT                   /locus_tag="YCR096C"
FT                   /product="homeodomain mating type protein a2"
FT   CDS_pept        complement(293179..293538)
FT                   /codon_start=1
FT                   /gene="HMRA2"
FT                   /gene_synonym="A2"
FT                   /locus_tag="YCR096C"
FT                   /product="homeodomain mating type protein a2"
FT                   /note="Silenced copy of a2 at HMR; similarity to Alpha2p;
FT                   required along with a1p for inhibiting expression of the HO
FT                   endonuclease in a/alpha HO/HO diploid cells with an active
FT                   mating-type interconversion system"
FT                   /db_xref="GOA:P0CY13"
FT                   /db_xref="InterPro:IPR001356"
FT                   /db_xref="InterPro:IPR009057"
FT                   /db_xref="UniProtKB/Swiss-Prot:P0CY13"
FT                   /protein_id="DAA07566.1"
FT                   /translation="MRSIENDRSNYQLTQKNKSADGLVFNVVTQDMINKSTKPYRGHRF
FT                   TKENVRILESWFAKNIENPYLDTKGLENLMKNTSLSRIQIKNWVSNRRRKEKTITIAPE
FT                   LADLLSGEPLAKKKE"
FT   gene            293835..294321
FT                   /gene="HMRA1"
FT                   /gene_synonym="YCR097WB"
FT                   /locus_tag="YCR097W"
FT   mRNA            join(293835..293939,293994..294239,294292..294321)
FT                   /gene="HMRA1"
FT                   /gene_synonym="YCR097WB"
FT                   /locus_tag="YCR097W"
FT                   /product="Hmra1p"
FT   CDS_pept        join(293835..293939,293994..294239,294292..294321)
FT                   /codon_start=1
FT                   /gene="HMRA1"
FT                   /gene_synonym="YCR097WB"
FT                   /locus_tag="YCR097W"
FT                   /product="Hmra1p"
FT                   /note="Silenced copy of a1 at HMR; homeobox corepressor
FT                   that interacts with Alpha2p to repress haploid-specific
FT                   gene transcription in diploid cells"
FT                   /db_xref="GOA:P0CY11"
FT                   /db_xref="InterPro:IPR001356"
FT                   /db_xref="InterPro:IPR009057"
FT                   /db_xref="InterPro:IPR017970"
FT                   /db_xref="PDB:1MH3"
FT                   /db_xref="PDB:1MH4"
FT                   /db_xref="UniProtKB/Swiss-Prot:P0CY11"
FT                   /experiment="EXISTENCE:direct assay:GO:0003714
FT                   transcription corepressor activity [PMID:1977088]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
FT                   [PMID:8411150]"
FT                   /experiment="EXISTENCE:direct assay:GO:0007532 regulation
FT                   of mating-type specific transcription, DNA-templated
FT                   [PMID:1977088]"
FT                   /protein_id="DAA07567.1"
FT                   /translation="MDDICSMAENINRTLFNILGTEIDEINLNTNNLYNFIMESNLTKV
FT                   EQHTLHKNISNNRLEIYHHIKKEKSPKGKSSISPQARAFLEQVFRRKQSLNSKEKEEVA
FT                   KKCGITPLQVRVWFINKRMRSK"
FT   rep_origin      294820..294901
FT                   /note="ARS318; ARS that becomes active if the nearby
FT                   ARS317/HMR-E silencer is deleted; active in only a small
FT                   fraction of cell cycles"
FT   repeat_region   295003..295330
FT                   /rpt_type=LONG_TERMINAL_REPEAT
FT                   /note="Ty1 LTR"
FT   gene            295484..295556
FT                   /locus_tag="tT(AGU)C"
FT   tRNA            295484..295556
FT                   /locus_tag="tT(AGU)C"
FT                   /product="tRNA-Thr"
FT                   /note="tT(AGU)C; Threonine tRNA (tRNA-Thr), predicted by
FT                   tRNAscan-SE analysis"
FT                   /experiment="EXISTENCE:curator inference:GO:0005829 cytosol
FT                   [PMID:9023104]"
FT                   /experiment="EXISTENCE:curator inference:GO:0006414
FT                   translational elongation [PMID:9023104]"
FT   repeat_region   complement(295958..296190)
FT                   /rpt_type=LONG_TERMINAL_REPEAT
FT                   /note="Ty1 LTR"
FT   gene            complement(297049..298605)
FT                   /gene="GIT1"
FT                   /locus_tag="YCR098C"
FT   mRNA            complement(297049..298605)
FT                   /gene="GIT1"
FT                   /locus_tag="YCR098C"
FT                   /product="Git1p"
FT   CDS_pept        complement(297049..298605)
FT                   /codon_start=1
FT                   /gene="GIT1"
FT                   /locus_tag="YCR098C"
FT                   /product="Git1p"
FT                   /note="Plasma membrane permease; mediates uptake of
FT                   glycerophosphoinositol and glycerophosphocholine as sources
FT                   of the nutrients inositol and phosphate; expression and
FT                   transport rate are regulated by phosphate and inositol
FT                   availability"
FT                   /db_xref="GOA:P25346"
FT                   /db_xref="InterPro:IPR005828"
FT                   /db_xref="InterPro:IPR005829"
FT                   /db_xref="InterPro:IPR020846"
FT                   /db_xref="InterPro:IPR036259"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25346"
FT                   /experiment="EXISTENCE:direct assay:GO:0000324 fungal-type
FT                   vacuole [PMID:26928762]"
FT                   /experiment="EXISTENCE:direct assay:GO:0001406
FT                   glycerophosphodiester transmembrane transporter activity
FT                   [PMID:16924500]"
FT                   /experiment="EXISTENCE:direct assay:GO:0001407
FT                   glycerophosphodiester transmembrane transport
FT                   [PMID:16924500]"
FT                   /experiment="EXISTENCE:direct assay:GO:0005886 plasma
FT                   membrane [PMID:16924500]"
FT                   /experiment="EXISTENCE:direct assay:GO:0071944 cell
FT                   periphery [PMID:26928762]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0015169
FT                   glycerol-3-phosphate transmembrane transporter activity
FT                   [PMID:20133652]"
FT                   /experiment="EXISTENCE:genetic interaction:GO:0015794
FT                   glycerol-3-phosphate transmembrane transport
FT                   [PMID:20133652]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0001406
FT                   glycerophosphodiester transmembrane transporter activity
FT                   [PMID:9691030]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0001407
FT                   glycerophosphodiester transmembrane transport
FT                   [PMID:9691030]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0005886 plasma
FT                   membrane [PMID:9691030]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0015169
FT                   glycerol-3-phosphate transmembrane transporter activity
FT                   [PMID:20133652]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0015794
FT                   glycerol-3-phosphate transmembrane transport
FT                   [PMID:20133652]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0055085
FT                   transmembrane transport [PMID:9691030]"
FT                   /protein_id="DAA07568.1"
FT                   /translation="MEDKDITSVNEKEVNENTNPRIIKYDAERRATRTETSKKDKWKNI
FT                   VTIIASGFALISDGYVNGSMSMLNKVFVMEYGKKNYSSKVSTRVSNAALVGIIFGQFFM
FT                   GIAADYYSRKSCILVATAILVIGSALCAASHGTTVPGMFWMLTVMRGLVGIGVGAEYPT
FT                   STLSANESANEYTTTKRGGILVMVTNLPLAFGGPFATIIFLIVYKICSGTKHLEAIWRT
FT                   VFAIGCFWPLSVFYFRWKTATTEVYEKGRIKRNIPYFLALKFYWKRLLGTCGTWFMYDF
FT                   VTFPNGIFSSTIISSVIKDQNDLVKVAEWNLLLGVLAVLGVPIGAYLSDRIGRKYTLMF
FT                   GFSGYIIFGLIIGCAYDQLKKITPLFIIFYAFMNMLGNAGPGDMLGVISSEASATAVRG
FT                   VFYGLSAVTGKIGSVVGVECFQPIRDNLGARWTFIIAAICGLIGIIITYFFVPHSLESD
FT                   LMKQDVEFHNYLVSNGWTGKMGFDETDEESMVRTIEVEENGTNCSKKNAEIISVRQVDQ
FT                   S"
FT   gene            complement(300832..301299)
FT                   /locus_tag="YCR099C"
FT   mRNA            complement(300832..301299)
FT                   /locus_tag="YCR099C"
FT                   /product="hypothetical protein"
FT   CDS_pept        complement(300832..301299)
FT                   /codon_start=1
FT                   /locus_tag="YCR099C"
FT                   /product="hypothetical protein"
FT                   /db_xref="GOA:P25657"
FT                   /db_xref="InterPro:IPR031777"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25657"
FT                   /protein_id="DAA07569.1"
FT                   /translation="MRSIFLLHFDYKTCEEEDFEDWNLADGKCLNGAKYMYKRRKQDAR
FT                   CLVKRTFKDMILHEIPCDSCTESDYECSSEFVRDAKGDCIPDYDQIALSDICDKANGET
FT                   VSLEPLQLIKGDKCKKPMEIEAMNIPCEKILRESSNGKKIATIENKFDFEI"
FT   gene            complement(301271..302221)
FT                   /gene="EMA35"
FT                   /locus_tag="YCR100C"
FT   mRNA            complement(301271..302221)
FT                   /gene="EMA35"
FT                   /locus_tag="YCR100C"
FT                   /product="Ema35p"
FT   CDS_pept        complement(301271..302221)
FT                   /codon_start=1
FT                   /gene="EMA35"
FT                   /locus_tag="YCR100C"
FT                   /product="Ema35p"
FT                   /note="hypothetical protein"
FT                   /db_xref="GOA:P25606"
FT                   /db_xref="InterPro:IPR031778"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25606"
FT                   /protein_id="DAA07570.1"
FT                   /translation="MSSTDIWISNDASTFQKAQLPTQLRHVKVIKIREDSIGRIILLIS
FT                   TEITNEENADPDLSEIFISDSQGLKFSPVEWTPNHQFGNFRLTFPDFLKGTIFGSFHPS
FT                   IDYSNHQVNYTENIAGGETKISVDNGLTWSNLKVVDEENADSFGCDITRPERCSLQGYF
FT                   YNLKLSNPSAGIILMTGSVGDDNEFDRKDRKTFISRDGGLTWRVAHNSSGLYATGDLGN
FT                   IIVYIPSPSYKDGDVQSKLYFSLDQGRTWNQYELVDALFYIHPLELINTTPDGSGSKFI
FT                   LSGHLITTASQEGNNTNISYIARSVLYAIDFSAAF"
FT   gene            complement(302482..303030)
FT                   /locus_tag="YCR101C"
FT   mRNA            complement(302482..303030)
FT                   /locus_tag="YCR101C"
FT                   /product="hypothetical protein"
FT   CDS_pept        complement(302482..303030)
FT                   /codon_start=1
FT                   /locus_tag="YCR101C"
FT                   /product="hypothetical protein"
FT                   /note="hypothetical protein; localizes to the membrane
FT                   fraction; YCR101C is not an essential gene"
FT                   /db_xref="GOA:P25607"
FT                   /db_xref="InterPro:IPR015943"
FT                   /db_xref="InterPro:IPR031778"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25607"
FT                   /experiment="EXISTENCE:direct assay:GO:0000324 fungal-type
FT                   vacuole [PMID:26928762]"
FT                   /experiment="EXISTENCE:direct assay:GO:0016020 membrane
FT                   [PMID:11935221]"
FT                   /protein_id="DAA07571.1"
FT                   /translation="MILLHAIYTLWVIILLPLLNAEKFVPKVTEAPIETSFNLVSFDDS
FT                   NTSIRLDGWGVVWISFDAGENWETVKEIEERIFRFTVDPFHGQERGFAFICESPKFYIT
FT                   DDRGESWRALTIPSSEEYLDGDCFITTHPRNKELLIANCYSYMIDADVLYDPSEIYLSN
FT                   DGNPFLKLNLPWKRKKTTI"
FT   gene            complement(304361..305467)
FT                   /locus_tag="YCR102C"
FT   mRNA            complement(304361..305467)
FT                   /locus_tag="YCR102C"
FT                   /product="hypothetical protein"
FT   CDS_pept        complement(304361..305467)
FT                   /codon_start=1
FT                   /locus_tag="YCR102C"
FT                   /product="hypothetical protein"
FT                   /note="hypothetical protein; involved in copper metabolism;
FT                   similar to C. carbonum toxD gene; member of the quinone
FT                   oxidoreductase family"
FT                   /db_xref="GOA:P25608"
FT                   /db_xref="InterPro:IPR011032"
FT                   /db_xref="InterPro:IPR013149"
FT                   /db_xref="InterPro:IPR020843"
FT                   /db_xref="InterPro:IPR036291"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25608"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0046688 response
FT                   to copper ion [PMID:15886332]"
FT                   /protein_id="DAA07572.1"
FT                   /translation="MKAVVIEDGKAVVKEGVPIPELEEGFVLIKTLAVAGNPTDWAHID
FT                   YKVGPQGSILGCDAAGQIVKLGPAVDPKDFSIGDYIYGFIHGSSVRFPSNGAFAEYSAI
FT                   STVVAYKSPNELKFLGEDVLPAGPVRSLEGAATIPVSLTTAGLVLTYNLGLNLKWEPST
FT                   PQRNGPILLWGGATAVGQSLIQLANKLNGFTKIIVVASRKHEKLLKEYGADQLFDYHDI
FT                   DVVEQIKHKYNNISYLVDCVANQNTLQQVYKCAADKQDATVVELTNLTEENVKKENRRQ
FT                   NVTIDRTRLYSIGGHEVPFGGITFPADPEARRAATEFVKFINPKISDGQIHHIPARVYK
FT                   NGLYDVPRILEDIKIGKNSGEKLVAVLN"
FT   gene            307801..308175
FT                   /gene="PAU3"
FT                   /locus_tag="YCR104W"
FT   mRNA            307801..308175
FT                   /gene="PAU3"
FT                   /locus_tag="YCR104W"
FT                   /product="seripauperin PAU3"
FT   CDS_pept        307801..308175
FT                   /codon_start=1
FT                   /gene="PAU3"
FT                   /locus_tag="YCR104W"
FT                   /product="seripauperin PAU3"
FT                   /note="Member of the seripauperin multigene family; encoded
FT                   mainly in subtelomeric region; active during alcoholic
FT                   fermentation; regulated by anaerobiosis; negatively
FT                   regulated by oxygen; repressed by heme"
FT                   /db_xref="GOA:P25610"
FT                   /db_xref="InterPro:IPR000992"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25610"
FT                   /protein_id="DAA07573.1"
FT                   /translation="MVKLTSIAAGVAAIAAGIAAAPATTTLSPSDERVNLVELGVYVSD
FT                   IRAHLAQYYLFQAAHPTETYPVEIAEAVFNYGDFTTMLTGIPAEQVTRVITGVPWYSTR
FT                   LRPAISSALSKDGIYTAIPK"
FT   gene            309070..310155
FT                   /gene="ADH7"
FT                   /gene_synonym="ADHVII"
FT                   /locus_tag="YCR105W"
FT   mRNA            309070..310155
FT                   /gene="ADH7"
FT                   /gene_synonym="ADHVII"
FT                   /locus_tag="YCR105W"
FT                   /product="NADP-dependent alcohol dehydrogenase"
FT   CDS_pept        309070..310155
FT                   /codon_start=1
FT                   /gene="ADH7"
FT                   /gene_synonym="ADHVII"
FT                   /locus_tag="YCR105W"
FT                   /product="NADP-dependent alcohol dehydrogenase"
FT                   /EC_number="1.1.1.2"
FT                   /note="NADPH-dependent medium chain alcohol dehydrogenase;
FT                   has broad substrate specificity; member of the cinnamyl
FT                   family of alcohol dehydrogenases; may be involved in fusel
FT                   alcohol synthesis or in aldehyde tolerance"
FT                   /db_xref="GOA:P25377"
FT                   /db_xref="InterPro:IPR002328"
FT                   /db_xref="InterPro:IPR011032"
FT                   /db_xref="InterPro:IPR013149"
FT                   /db_xref="InterPro:IPR013154"
FT                   /db_xref="InterPro:IPR020843"
FT                   /db_xref="InterPro:IPR029752"
FT                   /db_xref="InterPro:IPR036291"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25377"
FT                   /experiment="EXISTENCE:direct assay:GO:0006066 alcohol
FT                   metabolic process [PMID:12423374]"
FT                   /experiment="EXISTENCE:direct assay:GO:0008106 alcohol
FT                   dehydrogenase (NADP+) activity [PMID:12423374]"
FT                   /protein_id="DAA07574.1"
FT                   /translation="MLYPEKFQGIGISNAKDWKHPKLVSFDPKPFGDHDVDVEIEACGI
FT                   CGSDFHIAVGNWGPVPENQILGHEIIGRVVKVGSKCHTGVKIGDRVGVGAQALACFECE
FT                   RCKSDNEQYCTNDHVLTMWTPYKDGYISQGGFASHVRLHEHFAIQIPENIPSPLAAPLL
FT                   CGGITVFSPLLRNGCGPGKRVGIVGIGGIGHMGILLAKAMGAEVYAFSRGHSKREDSMK
FT                   LGADHYIAMLEDKGWTEQYSNALDLLVVCSSSLSKVNFDSIVKIMKIGGSIVSIAAPEV
FT                   NEKLVLKPLGLMGVSISSSAIGSRKEIEQLLKLVSEKNVKIWVEKLPISEEGVSHAFTR
FT                   MESGDVKYRFTLVDYDKKFHK"
FT   gene            310958..313456
FT                   /gene="RDS1"
FT                   /locus_tag="YCR106W"
FT   mRNA            310958..313456
FT                   /gene="RDS1"
FT                   /locus_tag="YCR106W"
FT                   /product="Rds1p"
FT   CDS_pept        310958..313456
FT                   /codon_start=1
FT                   /gene="RDS1"
FT                   /locus_tag="YCR106W"
FT                   /product="Rds1p"
FT                   /note="Putative zinc cluster transcription factor; involved
FT                   in conferring resistance to cycloheximide"
FT                   /db_xref="GOA:P25611"
FT                   /db_xref="InterPro:IPR001138"
FT                   /db_xref="InterPro:IPR036864"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25611"
FT                   /experiment="EXISTENCE:direct assay:GO:0043565
FT                   sequence-specific DNA binding [PMID:19111667]"
FT                   /experiment="EXISTENCE:mutant phenotype:GO:0009410 response
FT                   to xenobiotic stimulus [PMID:11943786]"
FT                   /protein_id="DAA07575.1"
FT                   /translation="MDSITVKKPRLRLVCLQCKKIKRKCDKLRPACSRCQQNSLQCEYE
FT                   ERTDLSANVAANDSDGFNSSHKLNFEQQPVLERTGLRYSLQVPEGVVNATLSIWNAEDM
FT                   LVIVGLVTFLDYPFAAHSLAQHDQYIRALCASLYGMALVDFSNYANGIPCEDTSRSILG
FT                   PLSFIEKAIFRRIEHSKQFRVQSAALGLLYNAFSMEEENFSTLLPSLIAEVEDVLMQKK
FT                   DCEILLRCFYQNIYPFYPFMDISLFESDLTSLLLQDDNNRWKISTEVKNVRKKIETLSL
FT                   LTIVMAMALMHSKLDANLLSMVKENASESARKLSLLCHKLLCLLDVFRYPNENTFTCLL
FT                   YFYVSEHLDPESPDCVLSPTNLLTLHHLLNLSMTLGLQYEPSKYKRFKDPEVIRQRRIL
FT                   WLGVQSLLFQISLAEGDAGKSNSEYMEAYLTDFEEYIEASSEYEKSSASESNVQMNDIV
FT                   WNKYKFHVILSKLMSDCTSVIQHPQLFHILGNIKRSEDFMAENFPTSSIYQPLHEKEPN
FT                   AIKVGKSTVLDVMDIQKTEIFLTNIVGSMCFLNIFDVLSLHFEKKCVMHWEEYEKNYHF
FT                   LTLKSFNAYLKLAGLISDYLENKFQGNILESRGYIIDKQICFMLVRIWMFQCRILLRFS
FT                   YKQESQKKLASSSISTNDNEKEDEMIVILERLIKHIRNQMAHLVDLAKGKLQDSYFGAY
FT                   QTVPMFRYVVYLIDVGGLVSVTNGFWDKISSDGEIPPKVQQAVRLKWGLDCNNSRRIKQ
FT                   KLISSQSLQSFNQVLLCQMEDAVLSSSFAIKANTAMSQNTAEEFFNISEEEALNQLLEN
FT                   NNFDAFWDLLGENLSDMPSL"
FT   gene            313890..314981
FT                   /gene="AAD3"
FT                   /locus_tag="YCR107W"
FT   mRNA            313890..314981
FT                   /gene="AAD3"
FT                   /locus_tag="YCR107W"
FT                   /product="putative aryl-alcohol dehydrogenase"
FT   CDS_pept        313890..314981
FT                   /codon_start=1
FT                   /gene="AAD3"
FT                   /locus_tag="YCR107W"
FT                   /product="putative aryl-alcohol dehydrogenase"
FT                   /note="Putative aryl-alcohol dehydrogenase; similar to P.
FT                   chrysosporium aryl-alcohol dehydrogenase; mutational
FT                   analysis has not yet revealed a physiological role; AAD3
FT                   has a paralog, AAD15, that arose from a segmental
FT                   duplication; members of the AAD gene family comprise three
FT                   pairs (AAD3 + AAD15, AAD6/AAD16 + AAD4, AAD10 + AAD14)
FT                   whose two genes are more related to one another than to
FT                   other members of the family"
FT                   /db_xref="GOA:P25612"
FT                   /db_xref="InterPro:IPR023210"
FT                   /db_xref="InterPro:IPR036812"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25612"
FT                   /protein_id="DAA07576.1"
FT                   /translation="MIGSASDSSSKLGRLRFLSETAAIKVSPLILGEVSYDGARSDFLK
FT                   SMNKNRAFELLDTFYEAGGNFIDAANNCQNEQSEEWIGEWIQSRRLRDQIVIATKFIKS
FT                   DKKYKAGESNTANYCGNHKRSLHVSVRDSLRKLQTDWIDILYVHWWDYMSSIEEFMDSL
FT                   HILVQQGKVLYLGVSDTPAWVVSAANYYATSYGKTPFSIYQGKWNVLNRDFERDIIPMA
FT                   RHFGMALAPWDVMGGGRFQSKKAMEERRKNGEGIRSFVGASEQTDAEIKISEALAKIAE
FT                   EHGTESVTAIAIAYVRSKAKNFFPSVEGGKIEDLKENIKALSIDLTPDNIKYLESIVPF
FT                   DIGFPNNFIVLNSLTQKYGTNNV"
FT   telomere        315783..316620
FT                   /note="TEL03R; Telomeric region on the right arm of
FT                   Chromosome III; composed of an X element core sequence, X
FT                   element combinatorial repeats, and a short terminal stretch
FT                   of telomeric repeats"
FT   rep_origin      315807..315879
FT                   /note="ARS319; Highly-active subtelomeric autonomously
FT                   replicating sequence; initiates replication in 90% of cell
FT                   cycles"
FT   gene            complement(315997..316188)
FT                   /locus_tag="YCR108C"
FT   mRNA            complement(315997..316188)
FT                   /locus_tag="YCR108C"
FT                   /product="hypothetical protein"
FT   CDS_pept        complement(315997..316188)
FT                   /codon_start=1
FT                   /locus_tag="YCR108C"
FT                   /product="hypothetical protein"
FT                   /note="hypothetical protein; identified by fungal homology
FT                   and RT-PCR"
FT                   /db_xref="EnsemblGenomes-Gn:YCR108C"
FT                   /db_xref="EnsemblGenomes-Tr:YCR108C"
FT                   /db_xref="GOA:Q3E819"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q3E819"
FT                   /protein_id="DAA07577.1"
FT                   /translation="MPYSPSLILMGHTHTDATVYTTLKLPYSHTPIHGPFSLNQYQMHP
FT                   HHYARHLPQRSIPCAIYP"
XX
SQ   Sequence 316620 BP; 98656 A; 62359 C; 59642 G; 95963 T; 0 other;
     cccacacacc acacccacac cacacccaca caccacacac accacaccca cacacccaca        60
     ccacaccaca cccacaccac acccacacac ccacacccac acaccacacc cacacacacc       120
     acacccacac acacccacac ccacacacca cacccacaca cacaccacac ccacacacac       180
     cacaccacac ccacaccaca cccacaccca cacaccacac ccacacccac accccacacc       240
     cacacaccac acccacacac accacaccca cacacaccca caccacaccc acacaccaca       300
     cccacacacc cacacccaca cacaccacac ccacaccaca cccacaccca cacacccaca       360
     ccctaacact accctaacac taccctattc taaccctgat tttacctgtc tcccaactta       420
     ctctccatta ccctacctct ccactcgtta ccctgtctca ttcaaccgta ccactcccaa       480
     ccaccatcca tctctctact tactaccacc aacccaccgt ccaccataac cgttaccctc       540
     caactacccg tatccaactc cactaccgct taccctacca tcgaccatgt cctactcact       600
     gtactgttgt tcacccacca tattgaaacg tctacaaatg atcgtaaata atacacatat       660
     acttatccta ccactctaat cccactacca catgccatac tcaccttcac ttgtattctg       720
     atcggtcata cgcacacgga tgctacagta tataccatct caaacttacc ctactttcat       780
     attccactcc atcacccatc tctcaccatc agtaccaaat gcactcgcat cattatgcac       840
     ggcacttgcc tcagcggtct ataccctgtg ccatttacgc ataacgccca tcattatcca       900
     cattttaata tctatatctc attcggcgac accaaatatt gtataactgc ccttaataca       960
     tacgttatac cacttttaca ccatatacta accactcaat ttatacacac ttatgtcaat      1020
     ataaccacaa aatcaccact aaaatcacct aaacataaaa atattctact cttcaacaat      1080
     aatacataaa cacactcaat tgcgtatcta taccaccatg acgtcattaa cgtaaaagtt      1140
     ccttaatatt gcaaattgct tgaacggatg ccatttcatg ttgaatgtgg taacccaata      1200
     gcatgatatg agtaatgctt tagtattgtt tcagagttgt ttcagtaatg ttttagacaa      1260
     ggagaacata tagtagcaaa cctctaatcc ggtagtactt aagaaactac agtttctatg      1320
     tacgaaagca gtaactatgt aattattaca tttacatgac atataggaag gtccaataaa      1380
     cttactacat tatgacctat aagctagatc gtaattcatt acgtcaacag gttatgagcc      1440
     ctcagagcaa tgcttctgag aacataatca atctatctag ccccaacaat tataaacagt      1500
     ggctgtacgg tatcgagacc gctgctgaat atgctaacga atatatgaac gaattcgttc      1560
     ataccggaga tatccaatca atgaaaaggg attacaatct cagcgcgaat gatgaaagct      1620
     ttgtcaaaac cgtatttaac agtttcctgg taaagctcta caagaaaact atcgtgggtg      1680
     aagctgcatg tgaaatgaac tggatatgtg atgattcgct tggaagggtc tctgcttatg      1740
     atattttctc gcacttcgaa gaaaactata atgaagtcac tattggatcc aggcttactc      1800
     ttatagagga cctaccaaat atatcctcca agcctgtaga tgaaattgct tcctttttga      1860
     aaactctatt cacgatgctt gaagacaata gcgaagaaca ggacaaaaaa aaaagacgcg      1920
     acaccaatat cgcgttgtta ttaatgacct tcttacccga gttaaaagaa tcattccacg      1980
     agaaattcgg tgactctaag gctcttcagc tatcacaagt cattagattc tgtaaattaa      2040
     atgcgtcatc gaattcatca tcttcggtct cagatgcatt ggttgcacaa gacagaagaa      2100
     actatcaaaa gaaaggaaat aagggatgta tataatttac ggagctgatc atcgcataag      2160
     caactgttct ctgcttaaac gaagaatacc agaagcacga atctttaaat tatatcctaa      2220
     tgacaaaacg agtagatctt catctgctag tgtcgcgatt cctgactatg aaacgcaagg      2280
     ccaaacagca ggacagataa caccgaagtc ctggctctgt atgttatctt cgactgttcc      2340
     agctaccaaa tcctcagaat ggatttttga cacaggatgt acttcccaca tgtgccacga      2400
     ccgttccatt ttttcatcat ttactagatc ctctaggaaa gactttgtca gaggagttgg      2460
     cggttccata cccatcatgg gctccggaac tgtaaacatt ggcactgttc aattacatga      2520
     cgtatcttac gttcctgatt taccagttaa cctgatatcc gtttgaaaac tatgcactaa      2580
     atcaaactct tctgttacgt tcacaaaaga gggtgtcact gtgcaatcac ctgatgatgt      2640
     ggtttctaca gctgggtatt cacaataaaa gactctggga agtacaaagc tcgccttgtc      2700
     gcccaaggac atactcaaaa ggctggtatt gactatcagg aaacctttgc accagtcatt      2760
     cgatatgact ctgttagatt atttctggcc cttgctagct gcctcaaact aatagtatat      2820
     cagatggacg ttgacactgc gtttctaaac tcaaccatgg atgagccgat ctacgtaaaa      2880
     caaccacccg ggtttgttaa cgagaggaat cccgactatg tatgggaact atacggcggt      2940
     atgtatggac tcaaacaagc cccattacta tggaacgaac atatcaacaa tactcttaaa      3000
     aagattggtt tctgtcgaca tgaaggcgaa catggcttat attttcgttc cacatctgat      3060
     ggtcccatct acattgccgt atacgtagac gacttacttg ttgctgctcc ctctcctaaa      3120
     atatatgaca gggttaagca agaattaacg aaattatact caatgaagga tctcggtaaa      3180
     gttgacaaat tcctcggtct taacattcat caatcgtcaa acggagacat cactctctcc      3240
     cttcaagact atattgctaa agctgcatct gaaagcgaaa taaacacatt taaacttaca      3300
     cagactccgc tctgcaactc aaagcctctt ttcgaaacaa cttccccgca tctaaaagac      3360
     atcactcctt atcagagcat agttggtcag cttctctttt gtgcaaatac tggtcgtccg      3420
     gacatatcgt atccagtctc attactctcc aggttccttc gagaacctcg cgcaatccat      3480
     ttggagtctg ctcggcgggt tctacggtac ctatatacca ccagaagtat gtgtctcaag      3540
     tatcgttctg gatctcagtt ggcattaact gtatattgtg atgcatctca tggagctatt      3600
     cacgatctac cacactctac tggggggtac gtgactctac ttgctggtgc tcccgttacg      3660
     tggtcatcga agaagctcaa gggtgtgatt cctgtaccat ctactgaggc agaatacatt      3720
     actgcaagtg aaactgtcat ggagatataa tggattcaaa acttgtttga acacttaggc      3780
     cagccactta tctcatcaac atcatatgta gataataaac ctgctataaa actgtctaaa      3840
     catcctgtat ttcacacgag agcaaaacac attgctttga gataccacaa gctaagaaat      3900
     gcagtggcag caggcataat taccatagaa catgttatca caaagaaaca agttgctgac      3960
     atatttacaa aaatccttcc agctgaatca tttaaaacac atagggctgt catgataagg      4020
     gaaccagaaa ctacaaaata accatactca tgcgtattca gttatggggg gatgttaaat      4080
     gtggtaacct aatagcatga tatgagtaat gctttagtat tgtttcagag ttgtttcagt      4140
     aatgttttag acaaagaaaa catataatag taaacctgta atcaggtagt acttaagaaa      4200
     ctatactttc tgtgtacaaa acactaacta tgtaattctt acatttacat aacatgtaga      4260
     aaggtccaat aaacttacta tattatgaca tataagttag atcgtaattc actacgtcaa      4320
     catatcccac gataaaaaaa ataccttgac tcaagtgccg aaacaggaaa taatgaaaga      4380
     tttcatacaa ggttgtttct aaggtgctat atgtccctac ggcctcgttt agccccatct      4440
     cgcatgcaat accgtaacat aggtatatac acacagagaa gtagtaattt tacgtgtctt      4500
     atacttattt tatatagaaa tgtccgacac ttgcgctaca ctaaggcata taagatagat      4560
     cttaattcct tgtattaaca tataaacaga caacataaca tagccagttt atcttactta      4620
     tcttttcctg gaagagatgg cattatttgt gtgtatcaaa gaggcctttt tcaattttca      4680
     ttttaatatt tttttaatat tcttatattg aacacatttt tctcccctag atttatgttt      4740
     cctattgctc tccatatcac attatatcta tgaatgaata tgcattgctc ttctgatact      4800
     atggtatgag aggccttggt aaagggcatc gataaccgaa agaatcatcc gcagagaagt      4860
     agaatcttag agcatatcgt ctcgttgaga ccgtatagat tcgcaaaaat aacagaaact      4920
     tgcgttaaca ttgaatttca aactcagttt tccataatta actgttaaaa aaggctacta      4980
     taagggtgtc aattactgtt ctgtttcgca ggattaattc cgttatgtgc tcttgtaatt      5040
     gagttagcgc ttcttatatc tcttcagtaa tgcagcagta ataaaacaca ttggcttcgc      5100
     tttcgctttt tttccaaatc attatcgaag attctttgct tatgatatac tggtgctcga      5160
     ggatgatgag aggacacaac tttttgaggc ttatcgttat cgtctgagtc acaacaacat      5220
     acattaactg tccacgattc agggatgtgc tatgagttca attttcgctg tagtgctgcc      5280
     attggcgctg ctactggtgt ctggaaaaac tccacagctt tcaatggaga tgtgactgca      5340
     cgagtgagac attatctgta ttagcttcac aaccatactc tgttagtaag gagccatagt      5400
     cgacatctgt ccagctcaat cgggtatgat atttgatatc cccaaaatac atggctgtac      5460
     catgtaaaat gagcggtata tcgaagatca gtatatttca gcctatacag gatcctacta      5520
     tttcaacaaa aatgatttca tcaaaattaa atcacgctgc aacattggtg aagaatctca      5580
     aaaggttagt aacatcaata tatcgcggag tagctatcat tgtggcagtt aacttaaagg      5640
     atatacagtt aattcaacaa gattttcaag tccatttttt ttgggcacgc tgaacacgct      5700
     caatgtagta cttgttttgg aaatcactcg caagtttaat gggacgaatt atatcagtaa      5760
     tgtgtaaatt ccgacacaat gttcggttag tagatttact gctggattat tgggttcacc      5820
     cgtagactgt tgccgactcc aagaaaacta tgatctcaat acaggcataa agaattgttg      5880
     tatctgtgcc catgtgatct gtaccttttt tgcggtacca aaatcgcatg ttgcactcac      5940
     actacggaac acatcaactt gtaacgacaa caatacaaaa taccaggaga catatcactt      6000
     tttttcgcct agaatgattt acaatggcat acacttagaa aagtgctatg acatgacgcc      6060
     cttactagaa gttacatgat tctccttttt tttctttctt tctttctttt tcggtacaac      6120
     ataattaatg cattcataca gagcgcattt ccagcatcat ttattggata gtaactcctc      6180
     ccgcactttc aatatcaatg acgctgactc ttttactgac gctgagtctt taccgacgct      6240
     gagtctttac cgacgctgag tctttaccga cgctgagtct ttaccgacgc ttgtgaaaat      6300
     aaaaagtacg acacagctat atgcgtcgca agttcagatg tgggtctatc gagcatgttt      6360
     atcctatcct gttatgtcat ttttatcgga agtaataaaa gtgtagaaat cacttgtttt      6420
     tgcctttttt gtgattttgc tttcattttt ttttgccctt ttttcaccag cttggggatc      6480
     aacatcctaa tttcttgtta cttcgattat gtctaaaaag tgccttgatt tgagagaaaa      6540
     tattttcctc atctggcaag acaaccaaac catcttcagt gaattcttcg tgtgtcgcct      6600
     tgtctattag ttccgggtct ctcatgaaca ttgtaaacgc aaagaacggt accgtacatg      6660
     ccaagccaac cgtcattatt attcgttgaa catatctgta agattcaacc acagcatctc      6720
     tttcgggtga gccccaagga taatcactaa tgaatgtata aggtgatgca tatgctattt      6780
     ctgccaatgt atcgtttcca aggttcttgt agagttggtt aggcatggtt tgtgtccata      6840
     tggcaccaga aacggaggca ccgatagcag cgcctagctt tgaaaaggta tactggatgc      6900
     cggttattac agccatccta ctatgcgtag tcatggcttg cagtatgacg atcactgaat      6960
     tgctgcatag gagaccactc aaacccatga taacagatgc agcgataaca ccttcatgag      7020
     acccagatcc tcctctgtat ttgtaaaaaa ggcccatgca caccatccat gcagcacaac      7080
     ctccgattac agaaagtttc agtttccttg tctttgccac caacaaactg tagaatggag      7140
     atgcagtagc agcaacaaag tcaggaaggt ttactatccg agcagccgaa gtggacgatt      7200
     ctttcatcga taccagcaaa acaggataca gatagtcaca cgaaatgaaa aaggtgaaaa      7260
     aattgaaaaa agtaacacca aggggtgccc aaattccacg atcacttagt aatttgaacg      7320
     gtagaagagg agatttggca aatttggcct cccaatataa aaaaatgaaa aataaacagc      7380
     cacctgaaac taaagtggca attatttttg aattgtgcca cttctgtgat gtctcattag      7440
     ccaacgtcaa agggacaagg atacacccta gcgacacagt tattaataat atgccaacaa      7500
     tatcgagttt ccagaataga aacaccaaat tctcaaataa tccgcccgtt ctttcctttc      7560
     tagcctgttc tttgagagat ctccactcag cagtctttga agatttgtac ttcatataaa      7620
     gaataagaaa tataattggc aaggcagaga gtgggtaaat aaaagcccac attgcaatat      7680
     tccaggacca gtttttctga ggatttgctg ctgtgataat attacctgaa atccatggta      7740
     ttatgatata tggccaatat gaggcgtact ggtaaaacat tctccacttc aaggaggaga      7800
     aatcagaaag tattaatgtc aggagcagat ttgttccgac gtatccacag ttatagaaaa      7860
     ccgatcctgc tgcatacatt gtgagacggg tcgcctgtga ttgaatgatg gttcccatta      7920
     tataaaaaat agttgcaact aaaaaaagcc ttagtcttcc gaagtggtca gagagtctgg      7980
     agtagacaac ttgggatccg acacttacaa cagcattgat aacttggaca gttgaaagta      8040
     aggagtgttc tgaatatgag ttcgtcgcat agcccgtata ggtcgatcta agtgtgtagt      8100
     ctaaactaat tccaaaccca catacaaacg cggtacttat cagtagaatt ttatatttca      8160
     aggaatcaaa ctgtgcagac ataatttcgt tttctttgag cttaaaaaag gtcgatgtca      8220
     tagagtacgt gtcatcgttt gagtgacgtt ctcgctcaat aatctcacag gactgcctaa      8280
     ttccactttt tttattactt gaggcaccaa caacactaga actcatccga taatttattt      8340
     acttgattat tccttttttt tttttttctc tttccagtcc ataaaactat tttacttttc      8400
     ttatttatgt aaatagtatt taagattcta cggtcgctac atctgctaga aatggaatta      8460
     ctttaataca ttccatgttc tcatatatac ttttactgac acctttcgtc actatttttt      8520
     gtttaacttt ttttttggaa gtactaaaat tatatgctcg taattattga gtatcaaaaa      8580
     aaaaaaaaaa aaaaattgct gtgacacccc ttcaatgtgg tgtctataca cctggtgact      8640
     ttaactttaa ctttgacctg tcgtcgtaca atcaacttag tttccgaaaa tccacgacga      8700
     accagttata ccgaagactt ttgtacgaca agaatactgt accgtcgaaa ctatctcttt      8760
     tcaaactgat gagtgaagct tgtgtttatg tctgttgaaa caaggaaaaa aatgcggtgc      8820
     ctgtcgacag gatatgcgca caagtgcaaa atcatcaaaa aattgagtac ctagatccgg      8880
     tggtgtagga cgagcaaagt tccttcataa acaaaccgta agggttactg atacacaatt      8940
     tcctttttgt aaagagtatt tgagcaaatt agtcagcgat tgaaaacaac accctttttt      9000
     ctatatatag taggtgaaag ttaacatgcg agtaaaagta gtgccacatt tcctttgcag      9060
     caggtgcaaa ttggtacata tttaacagat agcgccgcac ctcatatgca gcgcgtacat      9120
     gatacgagac gacaagatat gcaaaagata atagtgtcat cacaccttta tgagaagcga      9180
     attttttttt ttttttggtt taaatatata tatatacata tatatagata tagatataca      9240
     catgtataga tgtattctag ttatgcttat acctagaact gatcagacca gatcatacct      9300
     ggtatagagc ttaatcgata gaaattcaaa aatatggagg aaactaagta ctcttcgcag      9360
     caggagatag aagaagcatg tggttcagac gcttcattga atgctagagg tagcaatgat      9420
     tctccaatgg gactttcctt gtacctctgc ctggcttcgt gaactcttgt actattcata      9480
     actgcactgg atattttgat agtgggaact attattgacg tggtcgcaga acagttcgga      9540
     aactactcca aaacaggttg gctcgttaca ggctacagtt taccaaatgc tattctgagt      9600
     ctcatttggg gaagattcgc atctatcata ggtttccagc atagtctcat tttagcaata      9660
     cttatttttg aagccggatc cctaattgct gcccttgcct cttcaatgaa tatgctcatt      9720
     gtcggtagag ttgttgctag tgttggggga agcggacttc aaacgctttg ctttgttatt      9780
     ggttgtacga tggttggtga aaggtcacgt ccattggtga tttccatcct aagttgtgca      9840
     tttgctgtag ctgctatcgt tggtcctata atcggaggtg cctttacaac ccatgttacc      9900
     tggaggtggt gcttctatat caatcttcct atcggtggtc ttgccattat tatgttttta      9960
     ctcacatata aggccgagaa taagggtata cttcaacaaa ttaaagatgc tataggaaca     10020
     atctcgagct ttacttttag taagttcaga caccaagtta attttaaaag acttatgaat     10080
     ggcataatct tcaagtttga cttctttggt tttgccctct gctctgcagg gctggtcctt     10140
     ttcctactgg ggctaacctt tggtggtaat aaatatagtt ggaactctgg ccaagtcatc     10200
     gcatatttgg ttttgggtgt cttacttttt attttttcat tggtgtacga tttcttctta     10260
     ttcgataaat tcaacccgga acctgataat atatcctaca ggcctctcct tctaagaaga     10320
     ttggtagcaa aaccagccat aataataata aacatggtaa catttctatt atgtaccggt     10380
     tacaatgggc aaatgatata ctctgtccag tttttccaac ttatatttgc gtcgagtgca     10440
     tggaaagccg gtcttcactt gataccaatc gttattacca acgttattgc ggccattgca     10500
     agtggtgtga ttaccaaaaa gctcggttta gttaaaccac tcttaatatt tggaggcgtt     10560
     cttggggtaa ttggagcagg gcttatgaca cttatgacaa atacgtccac gaagtcaact     10620
     caaattggtg ttttgctatt accggggttt tcccttggat ttgctctaca agcatcgctc     10680
     atgagtgcac agcttcaaat taccaaagat cgtccagaag ctgctatgga ctttattgaa     10740
     gtaacagctt tcaatacatt catgaagtca ttaggtacaa ctcttggtgg tgtgctttca     10800
     accactgttt tttccgcctc ctttcacaac aaagtatcac gagctcatct agagccttac     10860
     gaaggaaaaa cggttgatga catgattttg tatcgtcttc aaaactacga cggttctcat     10920
     tcgactattg gaaacatttt aagcgactcc attaagaacg tattttggat ggatctaggg     10980
     ttttatgcct taggattttt gttttgtagt ttttcatcca ataagaaatt aatcatacca     11040
     aaaaaggacg agacaccaga agataattta gaagacaagt agcgcagtta ttttcttatt     11100
     ttcattttat ttttttcgcc ttttatacag acttcaacac aatcagaatc aaataggtgt     11160
     atcgcaatgg aatgtaattt cttaagtatt ctatatgtac ttaaaaccta ttaatatatg     11220
     gatcaacaca gtatcttatg aatgggtttt tgattttttt atgttttttt aaaacattaa     11280
     agttttcggc acggacttat ttggaattca aattattaat gaaagaacaa ttaactaatt     11340
     aatgtactta gtatttggcc attattatcg atttcggggg ccaaatctaa ccaaattcaa     11400
     cctacatttt ttcaaattga ttcaaacacc tttcacaata agatttttat atctagcgca     11460
     catagaatga aatgtaaaca aagatttcag aaaaatcgtc attcaaactt gtattagacg     11520
     agggacggag tgatttttgt gtttgttttt attaattgtg ggataggata gtagcaactc     11580
     ttggaggaga gcattgtcag ttgtccagtc tctgaagtta agtagtaagt ttgcggagtc     11640
     aaagggggat ggcttttgcc atttgtgaga gttgtgcggc agcatcttat tcaaatagag     11700
     ctgtattctg aagacctctt gtagaacatc atccatacta aaaagtaaat cgtcctgtcc     11760
     cattacgagc tgtagtagtg ctgtgaccct ctgtatattt acgttgccat gaagaaggta     11820
     atgggcgata ttttgataca attcctgagt tgcatgttgg attgagttta cgaagggtcg     11880
     ccagacggcc agaaacctcc aggcggagtt aacaactagt aatacggcat ccatgtttgc     11940
     atcagcgccg agcctatacc agtcactgag tagacgtttt cttgctcttt ttatgtcctg     12000
     acttcttttg acgagggggc attctctaga gacacaggca gttgcttcca gcaactgccg     12060
     tacggccgtt ctcatgctgt cgaggatttt ttttgggacg atattgtcat tatagggcag     12120
     tgtgtgactt atgaattgtt gtagaaggac gtctgtgatg ttggagatat gtattttgtt     12180
     aactcttctt gagacaattt ggccctggat agcgaagcgt gcggttacaa ataggtcgtc     12240
     ttgttcaaga aggtaggcga ggacattatc tatcagtaca aacatcttag tagtgtctga     12300
     ggagagggtt gattgtttat gtatttttgc gaaatatata tatatatata ttctacacag     12360
     atatatacat atttgttttt cgggctcatt ctttcttctt tgccagaggc tcaccgctca     12420
     agaggtccgc taattctgga gcgattgtta ttgttttttc ttttcttctt ctattcgaaa     12480
     cccagttttt gatttgaatg cgagataaac tggtattctt cattagattc tctaggccct     12540
     tggtatctag atatgggttc tcgatgttct ttgcaaacca actttctagt attcggacat     12600
     tttcttttgt aaaccggtgt cctctgtaag gtttagtact tttgtttatc atatcttgag     12660
     ttaccacatt aaataccaac ccatccgccg atttattttt ctgtgtaagt tgataattac     12720
     ttctatcgtt ttctatgctg cgcatttctt tgagtaatac agtaatggta gtagtgagtt     12780
     gagatgttgt ttgcaacaac ttcttctcct catcactaat cttacggttt ttgttggccc     12840
     tagataagaa tcctaatata tcccttaatt caacttcttc ttctgttgtt acactctctg     12900
     gtaacttagg taaattacag caaatagaaa agagcttttt atttatgtct agtatgctgg     12960
     atttaaactc atctgtgatt tgtggattta aaaggtcttt aatgggtatt ttattcattt     13020
     tttcttgctt atcttccttt ttttcttgcc cacttctaag ctgatttcaa tctctccttt     13080
     atatatattt ttaagttcca acattttatg tttcaaaaca ttaatgatgt ctgggttttg     13140
     tttgggatgc aatttattgc ttcccaatgt agaaaagtac atcatatgaa acaacttaaa     13200
     ctcttaacta cttcttttaa ccttcacttt ttatgaaatg tatcaaccat atataataac     13260
     ttaatagacg acattcacaa tatgtttact tcgaagcctg ctttcaaaat taagaacaaa     13320
     gcatccaaat catacagaaa cacagcggtt tcaaaaaagc tgaaagaaaa acgtctagct     13380
     gagcatgtga ggccaagctg cttcaatatt attcgaccac tcaagaaaga tatccagatt     13440
     cctgttcctt cctctcgatt tttaaataaa atccaaattc acaggatagc gtctggaagt     13500
     caaaatactc agtttcgaca gttcaataag acatctataa aatcttcaaa gaaatattta     13560
     aactcattta tggcttttag agcatattac tcacagtttg gctccggtgt aaaacaaaat     13620
     gtcttgtctt ctctgctcgc tgaagaatgg cacgcggaca aaatgcagca cggaatatgg     13680
     gactacttcg cgcaacagta taattttata aaccctggtt ttggttttgt agagtggttg     13740
     acgaataatt atgctgaagt acgtggtgac ggatattggg aagatgtgtt tgtacatttg     13800
     gccttataga gtgtggtcgt ggcggaggtt gtttatcttt cgagtactga atgttgtcag     13860
     tatagctatc ctatttgaaa ctccccatcg tcttgctctt gttcccaatg tttgtttata     13920
     cactcatatg gctataccct tatctacttg cctcttttgt ttatgtctat gtatttgtat     13980
     aaaatatgat attactcaga ctcaagcaaa caatcaaaga aatctttcac tgctcttttc     14040
     tgtgttccat ttagttttta gtacgattgc attgtctata tactgtattt accaaatctt     14100
     aattttagtc aaacattaat gtttactttc gtatttaagg atgtgtatac taagccttgg     14160
     gaaaatgcgt gttccttgtg ccatccgaaa gctacttcat aaaaaagata ctgttcattt     14220
     tcaagcccgc atagttggat caaatattaa ctatatatca acatggtcca aagatcgtaa     14280
     gtttggtcta atgttgtttt agcaaaaaaa aatactatac ctttcattaa cgtttattga     14340
     atttcttgaa aaaaaaaccc taaattatta taaaattata gcaggatagt tcttagtgga     14400
     agatattaag caaactattt tctgaattgc tatgcgaaat ttctctaatg ccagctgagt     14460
     aactaactct catggtacat aaaaatacgc atcttaaaaa atttgatatt tcatgattta     14520
     tttatagaaa taacgatgct tattgtgctt tgttgggtgt ttgacttcta tgttaactta     14580
     cttcaacatg aaagcccgac gtttgcaatg atatcctctt tttcacccga ttattttcat     14640
     ttattagtaa gtggggttct gggtgaaaaa atcaaaacaa aaatatgaat ttgtaatgat     14700
     ttttatattt tcgccggagg tgctggaaat ggcaaacgaa aatactatga cataaaagct     14760
     gggcacacta tgtacgttct ttttaatttt ttatcaacat gagaaaaatt catgaacact     14820
     gtaccttata ttatctaata aatgaagtaa gctttgcatc tccgtaacag ctgcatatat     14880
     ataattaagc gggagctttc tttcgatctc tttcattcca tatgtttatt atgtactgat     14940
     gaaaagcatt ttactaagtt gaggtctctg taagtatatt gtgaccatta tgctaaaata     15000
     ctggggtctt catttgtgtc aaattctacg taatagttcc cctttttctt acatttttat     15060
     actaaagagt tacggtattt atacaaacga ggggctttac tgtaatatat gattaagatt     15120
     caagctgaaa cattctaagt tagaggtata aaatgattat tgatgaaaga gctgcaaatg     15180
     tcggcaaaat ataaatacct tagatgttac cagctgggaa gattattacg gaacacattc     15240
     ttataaatct ataggaatac ataggattgt atttctattg acaaagtaca acctatattt     15300
     tatgttatgt tatgttatgt ttgctatgac tatagttgct tttcttcact tagtaaggat     15360
     taactaactc tcgagctagt aaatttgacg tgagaagcat aattatatta ctaatagaac     15420
     gatatctggt gtgttttatt acagactgca ctgagtgtta gaggtagaaa ttataagtta     15480
     aaaagcagta gtttatgctt tatgctcgag tatcaagtga atttgaacag gctagtgctt     15540
     cattggtact tctttcatgg ataattttga gcaaatttct gcagcatgtc cccctttata     15600
     caaattctgt gcattgccgg cctagaaata tgtcaacgtt ttggatatgt tgatgcttac     15660
     ttcgagaaat cttacactaa tacttctgga aaaaatcaat actagcaaaa tagtgatata     15720
     tgagtaaaat gtatgtagta catgtatgaa aattatcaag ggcaaattga tgcttcaacg     15780
     aaaaagttat tggattttca agcacttttt aaattcacaa tatttttttc tggaaatatg     15840
     aaattgtcag cgacttctat tacaggagtg tctttttttc tcatgctatc caacgcttct     15900
     tccaagtcct ttatagtatt agaggagccg ccacaagcaa taattatcac aatgtcatcc     15960
     gcagctaatt ttgagcccag tgcattttct aggatcttag tgttgtaacc caaatgcaat     16020
     gcggcgccac atgccggttc aatcaccata ttgaattgat gtgtatattt aagacaggtt     16080
     tcaataacat ctttgtcctc tattacaacg gatctggtgt tgtatttgcg agcgtattcg     16140
     aaagtttgat tagagatcac ggccgttcct agagaagtag caatacttgt tatcttcttg     16200
     aattgaactg gttggcctat tttcaaagaa gtattgaaaa catgacatcc attcgtttcc     16260
     acccccacaa tagggatcct atcagctaaa ccataccttt ccaaaccttg aataatacca     16320
     ttgtataaac cacctccacc aacgctgcat actatgcctt taaccttatt cacggaaata     16380
     tgttgcgatt tcaaatcttg tactatttca tctatcatag atgaatgtcc ttcccaaata     16440
     tccggattat cgaagggatg aacataaatg ggctcaatga cctgagagtc tattttattc     16500
     atgacatttg tttttaaaaa agtatctgct tctttccagt aggcaccact cacgataacc     16560
     tgggcaccgg tgttcctgat tttatctacc attctcttct ttgtcgctgt aggaaccacg     16620
     actgtacatg gtagagacag tctttgacat gctgttgcag cagcaaaacc ggcattaccg     16680
     ccagaactag cgaaaacctg aggagatctt ttaccgtcct tttgaattcg aatggcactt     16740
     ttcatgatga gattaccgat tcctctactt ttgaaggagc cacttggttg aaggcattca     16800
     tatttcaaga aaaattgtgc agaagccttt ccggggaaga attgacgtaa taatggtgtt     16860
     ttattgtaga ctatcgacat ctcgctggtt aattttcctg tctcttgtct atccagcact     16920
     taaaaaagag aaaactgtat aaacattttc cttttatttg gcgatattta tatacctgtg     16980
     ttcctcctca tattgtccct tttatcttat ctcatcgcaa acaatttgat aaagctttgg     17040
     cactatttaa tgacactcag tggaattaca tttccgctgg ggcttaacag gagccgccca     17100
     tgcggaatca tgtctccgcg cagaggactc attagtttcc gttcgcggtg attagtactc     17160
     gcgaaaagag aaaaagaaaa atagtaggaa catttcgcaa ttgatcaaaa tgtaaacagt     17220
     gcagtaaaga atgggaccat aagatagata agaaacagct cgcataagga aacaaggaca     17280
     catcgattaa tggcaaccca agccctagag gatatcacgg agaggctttt aataaggtcg     17340
     caagaggcta tcttgcaatt agatctgtgg atacaacgtc agcagagatc atcaatatgc     17400
     cagacaacag atcaagagtc attggataag ttatcccaac agtacaacca gtatatgtct     17460
     caactgaact ctttgtatgt tagatcggaa tctgttcgag acaagttgag caaggaacaa     17520
     caacgcagat tgatcacaga ggataatgag catcaacgca tagaagactt ggttcgtgaa     17580
     ttccaggata tcactttgag gttgaacgag ctggccaccg tcccaaatga agcgcctaat     17640
     gattctccac aatcgcaatc caccagaagt agtttagggt catttcaacc tcgaccattg     17700
     aaaataattg agaggcaacg tctgtgtatg gtaactccat cgaaaccacc aaaaaaatcg     17760
     gtaggcttta accccatcaa tgaagtcgat tgtccttcga aaactaactc tttaccgtgc     17820
     tcacctaaaa aacaacctgc aagaaatcgc actttacgtg cagccaaatc acatgatact     17880
     ggcttgaaca aaagtaagaa accgtcttcc tcggatacgt atgagtcttt cttcaaaaat     17940
     agacaaagac tttcgttgac cttctttgat gaaatggatg atgaagattt tgattctgat     18000
     caagatacta tcattctacc aaacataagt acccctccac atgttggtgt gaccgcaaag     18060
     ggtgctgaat tcgaaccttt aaggagatat aactctcacg aaagtatact atctaacaaa     18120
     ccagcacctt ctaagtcgct caatctggga agtttctccg cctcattctt caggccatct     18180
     aatccgacgt ttggaacttc gatatcaaat gtccaagtga actgtcatcc aactgttgca     18240
     gcgacaatgg ctcctagtcg taatggtcct cgtatttcaa gttctaaggc gttgttatca     18300
     tcattcattg cacgatcaga tacacatacg gtaaaagaga acaacacaaa tcttaagcat     18360
     gcatctttta tggataagtt taattcatcg ttaagcacaa tatcagaatc ttttcaaagt     18420
     aagaggggga gaaagaataa gggcatgaat gaagaacgaa tatcaaatca taatgtagca     18480
     caggaacaaa aaaataatat ggatataagc gtctctatag aagaattgca agatgctttg     18540
     aatacagaac tgctgtttta attaatgcct cctttaccta acctactctt cttttgctcc     18600
     aaatgtttat tctttttttt tttattcaga atatcttcaa gtttttttgt atctttttgt     18660
     attattatta aacttcttta taatatttgt cttataaaat cctatcataa catgactatg     18720
     gcttggccta gactcgggtg ccatcttttt taatgcgact acttcaagac agcttctgga     18780
     gttcaatcaa cttcttcgga aaagataaaa aaccactaat tatcaaagct atcttgtccg     18840
     ctttcaaaaa gtttattcga ttttgttttc gttttcattt tcattttttt attatgatgg     18900
     tcatggtggt agcggtggct cccttcagtt ttcctctttg gtgctattaa ttttctcgtt     18960
     ttccccatat atgtgataga agcttttgaa ctccccactg tcttgtaaga ctttagaatc     19020
     ttgactgtct tgttaccttc tttaaactta tcatttatgt ctgttctgga cgcaaaggat     19080
     ttgattattg atggatgttt gaaaacgcca actagtgatg tatctccatt ttccacctca     19140
     tcttcatcct ctgggcgctt ttctaagtca attattgtgt ttactgtttt tgaagtggtc     19200
     gaatcagttt gagaatttgt gaatgacttt atcgaactat tctgttttag ggtatataaa     19260
     tcttcaattg cttcatcatt gccatgttgt atccttgata gctccttatc cgtttcaaaa     19320
     tcctcataat tattactttt taggaaggat aagcttttct gcacaaagtc ttcagatatg     19380
     ataacctttt tgttcttttg atctacaggt ttctgttcat tatttcccgt attatcacct     19440
     acattaatgc tattgtcctg agtatctagg tcagtagccg tacttgtaat gtctaggtta     19500
     tattcctctt cagccccgaa ggggttttta tattcgataa tatcttccac catactttca     19560
     aaaaatgcgc tcgactttgg gtttttaaca agctttgcat catcgccaat ttctaatctc     19620
     ctttttctca tcaattctct ccttttgaga cgatattgtt gtagtacgtc gtcttcatca     19680
     tcatcactta gttctagctc taagctattt tttgctcttt tattacgaaa tcctccattt     19740
     ttaatgtcat aaagaatttt gtttatcatt ttgatatcca tttccttatt ttctgcggca     19800
     agcatttctc tgatttcatg aggattgaaa ttgttcttgg aataatcatc gatcattttt     19860
     tctaggtcag aatcatagtc gtcagatcct tctccatctg caccaccgat accatgccat     19920
     tcatcctcgg attcttcggc ttccatttca aagaagtttg tgacacctct tttcttcaac     19980
     tcttttatct tagcctcgtg ctccttttct ttctgtttta gttgcaattt ctctttgtca     20040
     atcagctgac ggcgaattgc ttcatcagct tcttcattga cgtatacatc atctttgact     20100
     tcattttcga ttgtatttct ttcggccatc acctcttcaa tgttttgtgt atctagaaca     20160
     ttggtttctt gaaatttgtc ggtatcctct ccgatattat caccgtaatg gcccagatta     20220
     atggcgatcc ttttcggtag actttcatca gctttctctt tgggtttggc ttcgacttcg     20280
     gtatcagagt ctgattcgtt aatgatatgt ttcacgtggt gggatttttt ttgctttaga     20340
     ataatttcat catcttcctt ttcactatcg gattctctac gattgtcatt ttcactacca     20400
     gatgattcat aatcggcaat ttcattacca ctcaatgcaa atccagaaga ctctgaccct     20460
     gagtcagaac cggaatcatg ggcgttcaat tgaaagtcat tttcttcaag tttttccctt     20520
     ctcttctctt tttgtctgat tcttttattt ctaagaattt cttgttctag caagttctct     20580
     actatttcct tttctttggc catatcctcc agcttcagac ctttcgtttc aatcacttct     20640
     ttctgatgat ccagaatttg tttcctgcta gctttcctta aggtatttaa tagtacatta     20700
     tgatcaactt ttgggtcttt acttttattc ggcctttgag acaacttttg attttgttta     20760
     gagagtcttg ccttcaggtt taatatagtc gcctttgata actgagagat tggcaaaacg     20820
     ctttcatctt tggataattt aatgctatcc atatcatcat ctccatattc gtcactgtcg     20880
     ctgtcgaggt ccagtgttat gcatttcgag gagtcaattt cccgtttcaa attattagca     20940
     taggagctca atagtggaac ccttttctca tttattcttg tctcatcagt tagatttaat     21000
     tcaacacttt tgttctcatg cagttcatcg tcattctgta ctggttttgg atgtgcattt     21060
     tccagcttta tatcatcgtc ctcatttgag gacgaatcgt caaaatcagc aagaaaagac     21120
     tctttagaaa aaaatttttt ggttggtatt ggcttttgcg gttttttgta ttcgacattt     21180
     ctagcttttt cccttttaga atcttctgaa gccaattcgc tttgtatttc ccgaattttt     21240
     aatgtgtgtg gtacttcatc ttgaagtgtt tgtgcgactg tatctatttg ggttttctgt     21300
     tcctgatgcg tagcctgtgg aataccaatt gcttgtgtct tatcctcatc atgcgcagtc     21360
     tgtggtggta catccatttg ggtgtcagga ccacgatttt gaatggactg aaataaagga     21420
     ctagttccaa taagttccgt tggaattata ggaattttcg gcgacagagc attagaatga     21480
     ttgctggaag tcgtaattat ttgggattgt ggttcaattg attttatagg ctgagtttgt     21540
     gaggttgcac cgctgctatc tatacgctgt gtagcccctg gccgtcctgt cgtgagaggt     21600
     gttttcagcg cttgagaagt ttcgttgacg agaccatctt ctttgattaa ttgggtgggt     21660
     ttcccgtcat taacggaatg gataggtacg ttaaacacct tgtcttgttg gatgctgaca     21720
     ggtattcttt gcgtctgcgt gaatgaagaa gagacatttt tctcactgta actattatct     21780
     ttaacttcgg atttctccag ctcttcacca ccatcgtaaa gattagagat taattgagtt     21840
     ggtaacgaat tctcactcct atcttttcca ttattgtgat tctgttcggg tgctttcttg     21900
     ccttctaatc tgttcttaac acgatttaat gtggcattgg caaataaaaa cccgttccca     21960
     gtcaactctg gcggattgtc tatgtcattg ggcccatttc cattagtatt atcgttctca     22020
     tctagtatgg gaacagcaac ttttttgtag gtggtagttc tcttctttgc agtcaacgag     22080
     gacaaagcat gcaaggcatc atccatcact aaaatatttg gtgataagtt caaaagcgaa     22140
     taacgaactt ccttagttgt ttgtctgttc ttggtttttt tccaacataa tgtgtttgaa     22200
     atgctattga agcaaacgcg ttttacgcat tctatctctt catgacgcgt cgaagaagga     22260
     taaggaaaat ttcaagtatt gatgtatatc tctctgcata tgagagccag tagagttggt     22320
     gtcctagtaa gaatttcttt cactttacaa acatatctaa gtaaacgaaa tgtgtgtgtg     22380
     tttctatata tatatagaca tatatgaagg attccgtagc ggtgtaaact aattttggtt     22440
     tggcttgtat gcttcttctt ccggagctat gaaatctttt gctctctctt cctgcctttc     22500
     gatttctctt tccatttgct tttccttttg ctcatttaat ttcttcattt gcttttctct     22560
     cttgcttaag aaatactcac cactttcaat ttccaaatca acctttctag gcaattgggc     22620
     aggaggaaat ggagtataga ccttcttttc gacgtttctg atcttcttgg gtttctttct     22680
     ggccacattc ctcttcttaa acatgggcaa gaatcttgac caatcttcat tggctaactc     22740
     tggccttttt gccaattctc tttttatcat taattccttg atatgataga tagggtgaat     22800
     atttttcata caatcttcta ctactcgacg gacctccttc aagcccttga agggacccat     22860
     ggcacttact gtgttacctt gtactagaat gtaacattta gttagaagtt ccaaagcctt     22920
     taaagtatta ccgttagggc ctacaagacg ttgtcttctc ttgacaaacc tttctttgtt     22980
     agtaacgaaa ttaccaattt taataacgtc gcatgccatg tcatcttgta ggatcttaac     23040
     ggcttgcggg aaaggaacgg atctcgccaa taatttgatc aaatctctgg ctttcaaaat     23100
     gatagcggga tcgtatgttt ttctagttgt ttttactgtc atagaacctt cgactaaatc     23160
     tagaacacac gctatgttgt gtttgtctag agcccttgtt acatcattcc aaatcgtctt     23220
     caagtaactt tctctgtatt taggaaacaa agtcataaaa ctggactctt cagcaaaagg     23280
     ttgaccggat gcgttatcct cttccttaaa ctcctctatc ttccatttat caatatcatc     23340
     cgtatcccaa ggtttatctc tgttatgtgt agacaccatc gtttgccaat ttggatattt     23400
     gtgtgaccct tttgtttgct gtctacttta caatagttaa cctcatcatc tctttttttt     23460
     gaaaattttc atatctcatc gctaaaagaa ttagaaatat aaggaaaaaa aaattttcgt     23520
     tttcagatgt gcaagcctgc tataataagg tacaataact caagggcatt tagcaaggaa     23580
     aaaatgggca agtgtagcat gaaaaagaaa ggtgtgggca agaatgttgg tgttggcaag     23640
     aaagtacaaa aaaagaggtc gatcagcacc gctgaaagga agagaacaaa gttacaagtg     23700
     gaaaagttaa acaaaagtag tgaaacaatg ataccgacgc tgctgcggga ggcaagtaca     23760
     caagagccag ctaaactgaa agctgagact actttgaaag ccgaggagct gatcaaggac     23820
     caggaaaagg actccaaggt acgagagcaa attcggacag aaaaatcaaa aacaaacgac     23880
     agcatgctga agcagatcga aatgatatcc ggcttttcct tatagggaat agtggtgaaa     23940
     gttacgtaaa tatatacata tagagcggaa tggtactgca tatttttatt attttttttt     24000
     ttgaatatat ataaagcatc gtcgcttaag actaaacctt cgaggatctg aggccagcgc     24060
     tggatctaaa gatggcgtcg ccctcggcgt agcctcttcc aacaccaaat ccaatgccta     24120
     gccatacagg aaatgcacgg cgcttgaaga ataatactga ggtgaacaca cccacgccaa     24180
     aacccatggc agtcttgacc agcatgttgg acaggacaat atcccactta gtgtcgagga     24240
     tcgtggacac ggagctgcca ttcttgttag aatccttgga gggagtgctt ttcgctggtt     24300
     gttgtgtttg tgcttgttcg gacatggtat attttgtctt tttccgtgtt tattccctct     24360
     cgtagcaaag ttaatctgcc aattgacagt agtttaatat atggtattat cgttgtttga     24420
     agccctttaa aaggaaaaaa cgggttaggg ccacccggcg cgaagtaata gctgctgatt     24480
     ggtcagaata gtaaaacggc ttgaattgat agtatatcgt actgtatata ccttatattt     24540
     gggctaataa tcatctccca aatgctccag tatacatgtc acctagctat gtatgaggtt     24600
     gactacctta tatgcagcta ctacacaata actgtagtat cgcgctgcac gagcgtgacg     24660
     gcggttaaat ctggattttt tgccaccttt tttatacgaa aataagaact aggtaaatag     24720
     gaaggaatgg ttggatttga gtttaaaaat agagggaata cttggagatg cgattgttgc     24780
     tgtgcaagaa ttggtttgcg tcacctgtaa tctcaccact actgtatacc cgctccttat     24840
     attcaatggc taacactact agtttcccta ttgctcccca ggccccgcct aattggtcgt     24900
     tcactcccag cgatattagt gggaaaacca acgaaatcat caacaacagc aacaatttct     24960
     atgattctat gagtaaggta gagagccctt ccgtgagtaa ttttgtggag cctttcatga     25020
     agtttgaaaa tgaattgggc ccaataatta accaattaac tttcttacag catgtgtcgt     25080
     ctgataaaga aattagggac gcatctgtga actcctcaat gaaactggat gagttgaaca     25140
     tcgatctatc tctgcgtcac gacatctttt tgcaattcgc ccgcgtctgg caggatgttc     25200
     aatcgaaggc agattctgtg gaaagagaaa ctttcaaata cgttgagaag tcttacaagg     25260
     actacattca ttctggtttg gaacttgacg agggaaaccg attgaaaatc aaagagatca     25320
     aaaagaagat ctccgttaac tctattaatt tttcgaagaa tctgggagaa caaaaggaat     25380
     acatcacttt caccaaagaa caattggaag gtgtgccgga ttctattttg acgcagttcg     25440
     agacaataaa atctgacaaa gatagcaatg aaaccttgta taaagtcacc ttcaaatatc     25500
     cggacatttt tcccgtgatg aaattggcat cctcagctca gactagaaag caggcctttt     25560
     tggccgacca aaataaggtc cctgaaaatg aagctatact gttggataca ttgaagctgc     25620
     gtgacgaatt ggcctcgtta ttgggctatg acacgtatgc gaactacaac ctgtatgata     25680
     aaatggctga agatagcact acggtaatga actttttgaa tgatttgaag gacaagctaa     25740
     ttccgctggg cagaaaggaa ctacaggtct tgcaagatat gaaagccgaa gatgttaaga     25800
     aacttaacca gggtgcagat ccaaactact acatttggga ccaccgttac tacgataaca     25860
     aatatttgtt agaaaacttc aatgtggacc tagaaaagat ttctgaatat tttccactag     25920
     aggctacgat tactggtatg ctggaaatat acgaaacatt gtttaatttg aagtttatcg     25980
     agacgaaaga ttctcaaaac aaatctgttt ggcatgacga cgtcaaacaa atcgccgttt     26040
     ggaatatgga tgatccaaag tctccaaact ttgttggttg gatttatttc gatttacatc     26100
     ctcgtgatgg taaatatggc cacgctgcca attttggttt atcgtcatca ttcatgattg     26160
     atgacaccac aagatcgtat ccggttactg cgttggtttg caatttctcc aaatctacga     26220
     aggataaacc ttctctactg aagcataacg aaatagtgac ctttttccat gaattgggcc     26280
     atggtatcca tgacctggtg ggacaaaaca aggaatcgag gtttaatggc cccggatctg     26340
     ttccatggga ttttgtggag gcaccttccc aaatgttaga attttggact tggaataaga     26400
     atgaattaat caacctctca tcacattaca aaacgggcga aaaaattcca gaatctttga     26460
     tcaattcatt gatcaaaact aaacacgtaa atggtgcttt attcactcta agacaattac     26520
     attttgggtt atttgatatg aaagtacata cttgtaaaga cttgcaaaac ctgtcaattt     26580
     gcgatacctg gaaccaattg agacaggata tttctttgat ttctaatggt ggtacgttat     26640
     ccaagggtta tgattcattt ggccatataa tgtcagactc ttactctgcc ggttattacg     26700
     gttatctatg ggcggaagtc tttgcaactg atatgtatca caccaaattc gctaaggatc     26760
     cgttaaatgc caagaatggg atacaatacc gtgatattgt gttggctcgt ggtggccttt     26820
     atgatattaa tgataatctg aaagaatttt tgggtaggga accttctaag gatgctttct     26880
     tgaaggagct gggcttacag aactaaattc gttcaagcat aaaattatac aattattcta     26940
     caaagtgtta ttatgttaga taatctttta aataacctcg tccctggata gattaaaacc     27000
     attaaatagc tcaaatcttg gagtaaagca gcagtaatat gtctgatatg ttcgttatat     27060
     tttttcttga agtttatcaa cttatccttt actagaccat ttccctcccc atccaatcgt     27120
     tgatcgattt taaatttcac cttgcataat tttattaatt tccatacaca ttttatcact     27180
     gaaatgcacg agtaacacag ccaaactttc cgtaatagcc cacttacata taacttatcg     27240
     ttgaccacgc ctaggttttc caatactgcg aagaaatcaa gcagcgaact tacaccactc     27300
     catatattct cccatatatc ttttgcactg atttcagccg tatttttctt cgaaaccatt     27360
     caactttctt ttcttcttcc tttactttta ttcatctcct ctttacttct tacctcagag     27420
     tcgaacattg aaatcatttc ccgcgaattt ttcgattata attacccttt ctacttaaca     27480
     agaagcaata agagcaaagg ggcgaaatgc ttgtcccata ctttggcttt tggatgtgac     27540
     attaggagcc ttatctcctc ttaatgcctt aagtcaaaaa atagtttttg ggatatatct     27600
     tgtgatcaaa tgctttgcaa aagggtaaaa cagcgtttac aataggatag ccaaaagtaa     27660
     aaaaaaaaaa aaaaaaaaaa agaaggaagt tagtatcgag ctcaaacaat tttagttttg     27720
     ctggacatat tttcagtttc attactgtat atttgcagct tggtttttgt cgctctgtag     27780
     tcttgtttca cacttcgtca tttccgagtt tcatcttgcg acataacttg tttcaacttt     27840
     tcaagtgcga ctttttgtta aatattatga catagaagaa agtagaacag ccattataaa     27900
     acaaaagaga agtgagaata ctattaagat ggcattccaa gatccaactt acgaccagaa     27960
     taaaagcaga cacatcaaca acagtcactt gcaagggcca aaccaggaaa caatagaaat     28020
     gaaatctaaa cacgtatcat tcaaaccctc tagagacttc catacaaacg attactcgaa     28080
     taactacatt catgggaagt cgctaccgca acagcatgtt actaatattg agaatagggt     28140
     tgatggctat ccaaaacttc agaaattatt tcaggcgaaa gctaaacaaa taaatcaatt     28200
     tgccactacg ccatttgggt gtaaaatcgg aatagattcc attgttccaa cgttgaatca     28260
     ctggatacag aacgaaaatt tgactttcga cgtggtgatg attggctgct taacagaaaa     28320
     tcagtttatt tacccaattt taacccaatt gccattggat agattgatct ccaaaccagg     28380
     tttcctgttc atctgggcca attctcaaaa aatcaatgaa cttactaaac ttttgaataa     28440
     tgaaatatgg gctaaaaagt ttagaagaag tgaagaattg gtttttgttc ctattgacaa     28500
     gaaatcaccg ttttatccag gtttagatca ggacgatgaa acgttgatgg aaaaaatgca     28560
     atggcactgt tggatgtgta tcacaggtac agtaaggagg tctacagatg gacatcttat     28620
     tcattgtaac gtagacactg acttgagtat cgaaacgaag gacaccacta atggtgctgt     28680
     accatcccat ttgtatcgta ttgcagaaaa cttctctacc gcgactagac gattacatat     28740
     tattcctgca aggactggtt acgagacacc cgtcaaagta agacctggct gggttatagt     28800
     gagcccagat gttatgttgg ataacttctc acccaagaga tataaagaag agatagctaa     28860
     tttaggttcg aatatcccat taaaaaatga gattgagctg ttaagaccaa gaagtccagt     28920
     acaaaaagca caataaagca tcaacacata aatccttgct tagctcaatt aaatatacta     28980
     gtaaataagt atataaacaa taattttgca ttttatttta ctggaaactc ttctcaaaac     29040
     caaattgcgc aaggattgat tcagtacaat tatgcaaact cgaaaagtaa ataaacaaaa     29100
     agatacagtt gagtgaaagg taaataaaca ttattctact tgattttcct ctgttttttc     29160
     catttttctt ttttgtcttt tcgtgttcta gcgtgttcac tttttcagcc atgtaattac     29220
     ttaaatagga agtttacacg atgttctcgc ataaaaagct ggaagtgcag aacaaagagg     29280
     aagaaaatag gaacagagaa tttgtttgtt tatttgtttg tttgcttgtt tgtttgtttg     29340
     ttttgatttg aagtcgaggt acttattcga aataattatt ttgcccaggg ttttggatag     29400
     ttttttgttt tccaattaga tttttagaaa tattttatca tagttttttg tttatttatt     29460
     tgtttattta tttgttgatt tgtttattta tttgttggtt tgtttattta agtttgtaaa     29520
     tgtttaataa acaaaacaat atttgcaagc cattgaaaac tttgtaaatt tgtttgagaa     29580
     tttacgaaac aatgaaaatt aaggactctt tgatggtgaa cgaattacta ctttgcagca     29640
     ggtaattctc taaaactcag aaacaaggca tgtatttttc actaggaaaa agaaggaaaa     29700
     tgggactaca gtattaggga aacaggatta aaattcgtag gtaataataa cccatacttt     29760
     cattgtagca gtactttcgt taataaaatg gatattgttg tacttcggta gatgttatat     29820
     tctaaagagt taaattatcc aattccaaat tctagggacg gtttccaaag atttgtattg     29880
     tccagtgaca taattttcac taaaacattg atctgtttaa taggtttgct ataaatgcac     29940
     aataattttt cacccatgat acccaatttc aagagaagca attgctacat ataattattt     30000
     aggctttact atctactact cattgactgt gcccttttac acaattataa caaatatgtc     30060
     aaagcagatg ccatgaactt tgtatctgaa tttttgattt ccttttaatt ctaattgcag     30120
     acgacgtaaa tatagttctg aatttcaaag tcactgttaa ttaattgttc taattgtttg     30180
     gtttttttaa tataaatcac tagtgcttaa gttctgttga cgcacacagt acctatcttt     30240
     gattccttcg tgcaaacagt attccggcac gttaattgat accaaaaaga tttcaaaatc     30300
     agatgcttca agactaattg tatactttat gtgacttctg gagtttaatt tgttgtattg     30360
     atgagataat attgtctatt atattgccaa taacaaccag cgccaggtgt actaagtcga     30420
     gatgacagaa aatttataat aagtgtaaat acaataaatt ttgtaaataa ataactactt     30480
     caatagaaat ctcaaagtcg aagaaacaca gaacacagaa tgaaactgga ctaaatgatt     30540
     ttcaataaag gaaaagcacg aaaaattttt tgaacttttt tgggacagcg tggatcgtgt     30600
     aattactgta ttgggaaatt tacacgattc tcgacaaata aagaaaaagg cgcgtttaaa     30660
     gacttacaag cacacctttg aattattttt gttctctatg attatcaaat gtgctagtgt     30720
     ttgcaagatg gtgctttttt ttctttagat tgccacgttt ctgctcctct ttgtggtttt     30780
     cttttttttt ttcaatctta cttataaaat gaatatttca attgatgaat agctatatat     30840
     tggatacaaa aattagcatt taatcgaaaa ctgcagcatg tatttaatcg aaaactacag     30900
     catgtagcta tgatacgaca gaagattttt gtttttatag ttaagtcaag aagaaattct     30960
     atttgtccag caatccggcg caaagaagac tactaaaggg tattgaaaaa tttctagaac     31020
     cagaaataat cgaaagcatt actttttttg gctctataaa ggagttctgg acagcttgaa     31080
     cttccgaagt ctgtctgttt agctcgttaa gataaatctc aaaagagtag caagcaggtg     31140
     ggagggataa tttggattaa agtgtatata ttgcgtatat atagccacgt aaacctcaca     31200
     ctattgagtt taaacatttt tcaccttacg ttattattct tttgtctaat tttaatctcc     31260
     tccagtatac taaaaccgca aaagcgggtt acccagcttg tttctttttg tctgaaaaat     31320
     tttttgcgat gcccattatg aaaaattggc aataatagta tagtagttag tttaagttta     31380
     gattctttca atactcattc tgcttcagtt tgtagttaga tttaactcaa tagaggtgat     31440
     tggcaaaaat gggtaagaca caaaagaaga atagtaaggg acgtttagat agatactatt     31500
     atctagcaaa ggagaaaggt tatcgtgctc gttcatcctt taagattatt cagattaatg     31560
     aaaagtatgg ccacttctta gaaaaatcga aggttgttat tgatctgtgt gctgctcctg     31620
     gttcatggtg tcaagttgca tccaaactct gtcctgtcaa ctccttaatt attggtgttg     31680
     atattgttcc aatgaagccg atgcccaatg ttataacttt tcaaagtgat attacaacag     31740
     aagattgtag atcaaaattg aggggttata tgaagacttg gaaagctgat acagtgttgc     31800
     atgatggtgc tcctaatgtt ggtttgggtt gggttcagga tgctttcacc caatctcaat     31860
     taaccttaca agctttgaag ttggccgtcg aaaatttggt ggtgaacggt acttttgtta     31920
     ctaaaatttt cagatccaag gattataata aattgatttg ggttttccaa caattgtttg     31980
     agaaagttga agccacaaaa ccacccgcat caagaaatgt ttctgcagaa atttttgtag     32040
     tgtgtaaagg tttcaaggca ccaaagaggc tggacccaag attactggat ccaaaagaag     32100
     tttttgaaga attgccagat gggcaacaga atatggagtc caagatttat aatcccgaaa     32160
     aaaaagttag aaaaagacaa ggttatgagg aaggtgataa tttactgtat catgaaacct     32220
     caattttgga ttttgtcagg acggaagacc caataagcat gcttggagaa atgaataagt     32280
     ttacaattga tgagaatgac catgaatgga agatcttgaa gaaattgaaa caaaccacag     32340
     acgagttccg ttcctgtatt gaagatttaa aagtcttggg taaaaaggat tttaaaatga     32400
     tcctaagatg gagaaagatt gcaagggaaa tcttgggcat cgaagttaag gacgacgcta     32460
     aaacagaaat tgaagtagta ccgttaacag aagaggagca aattgaaaaa gatttgcaag     32520
     gtttacagga gaagcagcgt ctaaatgtca agcgcgaaag aagaaggaag aacgaaatga     32580
     agcaaaagga actacagaga atgcaaatga acatgataac ccccactgat attggtattg     32640
     aagccgcaag tttgggtaaa gaatcgttgt ttaatttgaa aactgcagaa aagactggta     32700
     tcttgaacga cttggcgaag ggtaagaaaa gaatgatttt tacagacgat gaattagcca     32760
     aagataatga tatttacatt gatgaaaaca tcatgatcaa agataaggat tctgccgctg     32820
     atgcggacga tttagaaagc gagttgaatg ccatgtatag tgattataaa actagaaggt     32880
     cggaaaggga tgccaagttt agagctaagc aagcacgtgg tggcgataat gaggaagaat     32940
     ggaccggttt taatgaggga agtctagaaa agaaagaaga ggaaggtaaa gattatatcg     33000
     aagacaatga cgatgaaggt gtcgaaggag actccgatga tgatgaagcc atcaccaatt     33060
     tgattagcaa attgaaggga caagaaggtg atcacaaatt gagtagtaag gcacgtatga     33120
     ttttcaatga tccgatattt aataacgttg aacctgattt gccagtaaat accgtcaatg     33180
     atggcataat gagttccgag tctgttggtg atatttctaa attaaataag aaaagaaaac     33240
     atgaagaaat gcaccagaaa caagatgaag cagattcttc ggatgagagt tcaagtgatg     33300
     actccgattt cgaaattgtg gccaacgata atgcatcaga agaattcgat tctgattatg     33360
     attcagagga agaaaaaaat caaacaaaga aagaaaagca ttccagagac attgatattg     33420
     ctactgttga agccatgact ttggcacatc agttagcatt gggtcagaaa aacaagcatg     33480
     atcttgttga tgaaggtttc aatagataca ccttccgtga caccgaaaat ttgccagatt     33540
     ggtttttaga agatgaaaag gaacattcaa agataaataa gccgattact aaggaggcag     33600
     cgatggcaat taaagaaaaa ataaaggcaa tgaacgcccg tcctattaag aaggttgctg     33660
     aagctaaggc aagaaagagg atgcgtgccg tagctcggtt agaaaagatc aagaagaagg     33720
     cgggcttgat taacgatgat tcagacaaga cagagaagga caaggctgaa gaaatttcta     33780
     gattgatgcg taaggttacc aaaaaaccaa agaccaagcc aaaggttact ttggttgttg     33840
     cctcaggtag gaacaaaggt ttggcaggta gaccaaaggg cgttaagggt aagtataaga     33900
     tggttgatgg tgtcatgaag aatgaacaaa gagccctaag acgtatcgca aagaagcatc     33960
     acaagaaaaa gtagtaacaa agagcattat ttttccattc ccttgtataa tattgaaaat     34020
     aaaggaaaag aaagcaatag atatattatg tatacataga attaatcaaa ttatcatcaa     34080
     aaaacttata ggaaacctat cgttttgaat tcagaaaata cgagtgcaca gtagaacaat     34140
     ttttattccc gttttactga tcttttcttc ttgttgttac caaatacctt ggagaaaatg     34200
     tatatgatgg agatgagtaa gcatagtaac gtaccatttt tgatcttgga ataatccttt     34260
     gtgtcaggcc ttggaattgg tactagaaga gttgtcgagt tcaaatggcg gaatgtagta     34320
     tcgtctgtaa agagagattc atatcctaga ccttttttat aaaatggatt acgggaaact     34380
     ttattgtcac ctgtgtcgca ggctaatata acttctggat caaatgaaac ttctaattta     34440
     tcccctttat tattagaagg ctcaatatat ctagtatgca atgtcacttc attcattgtg     34500
     ccggctttca attcaaagat actttcagaa ccccatgcct tatctcgaag agagtattct     34560
     ggtaattcta agtcgtcttc tccaaaaagt agtaagggag aggattggaa tttatcgata     34620
     aataattcta acggcaattg caggtgcatt agatacatgc atttagggcg ttcttcgaaa     34680
     tctgtgagat caatcatgat ttttggatgc aaaccgatag gttcattcag atatagtgat     34740
     gtcgtagtcg tcgagtgatt gtatgcgata tggccctgtt tatacaataa ggatgttttc     34800
     tgacatcttt ccattttacc atcgtccatc ctccaattac aacgtattcc accaatatcg     34860
     acatcacttt catcacttgc atccacaaag aatacaccta cttcgagttt ctcatctttc     34920
     actcttgcaa ttgtaaattc ttcaccctgt ttcaacagac gatattcaac aatttggatt     34980
     tgtgtgggct ccactgatat atcatatgta aaatcttctg gattccatga cagattcaaa     35040
     tctacttcgg gaggcaagta ctgctctatg tcaaacttct cactgtgaaa tgaattgtag     35100
     actgggttag taataaacct ttccggcaca tccgaagaat ttgagtaaac tgaaaagcca     35160
     gcactcagtt cattttctat aacgcttaaa cttctagcca agtccgctct gggcctccaa     35220
     gtgattctcg taaaggattt atccaagctt ccagtcctct ctaatagcca cctttgttgt     35280
     aaaaccacac cagaacctcc acgaacagtc aaatgagtgt cattttggcg catatgatta     35340
     ccgatatcct caggggcatt gtagagtaca gtcactctat gtcttgtcac cattactcag     35400
     ctagaaacgc acacttcttg cgtttattct cctcccgatt tgattatgat tagcgtttcc     35460
     attatttgat cttttttatc agggggatct tcaaagaaag gaactttttt taggaaaaaa     35520
     aaaataatca tcttttatta catgtgtaat acttcaagca atcataaaca agagttaaga     35580
     aggcaaagtt ctgctgttag tgtgtcctcc aatactcttg cacgacaaag ttttagttat     35640
     ccccttctac gtgtattgtt cctccgtggt cgattgtgtt caaagattgg gagctctttt     35700
     cgtgttttgc actaagagca tactgttaat ccgcaaaggc cactaaaact tacctgcatt     35760
     tgtctactta aagatacatt ccaactattt acattcattt ttatttctaa aagagcattc     35820
     tgaaccctcg gcaattattt catactcctt ctcagaatag gaaaatgccc aatacgcata     35880
     ctcaacatgt gcaaatatca gagccaaatc ctgtaaatac tttgtctaca ccatccaaaa     35940
     gaggtcaccg ccatcgcaga tcgctagcaa tatcaggaga ttttgatttt ttgaaacagc     36000
     ctgcagcaat tgtgaattta ccacctccac aggcggctga aaattgtcct tcaactgccc     36060
     caactgctgt atcaagtaca ttatcgccaa tacgctacaa tagatttcct tgcaaaacca     36120
     atgaagacgc tggaacgtta gatttgcctg aaccaagatt ttatccgtta tcaccaaaga     36180
     acaatctgca aacaccaagt ccacgatttt tcattagtga agagccaagt ttttcatcgc     36240
     cagttaaagg cgtcccagat gccattatta accttgacga tgcgttgaag acaaggccta     36300
     ggtcatttaa atcacataga agatctgaat ccgctcctcc tgatttggag gttatggtag     36360
     ataagggcaa ttgtgcagcc ggttctaact ctatgattaa agaagaagag gactccttaa     36420
     ttgaaccaga atcgaaaaat gaatattatg agcaaaagct tccaacagca ctattatccc     36480
     cactgcggcc ttccctttgt gtatctgaac aggccattga tgtagatgat tcagctctca     36540
     atgggtcacc gacccatcac aaccatggga tgcaaaacgc caatgcacgg aattccaaca     36600
     cattcaattc gttgaagatc aaaggccaaa agcaaagata ttatcattat acgaagcagc     36660
     tacctttgac cgtaggctgt gactcgcaat ctccaaaaga acaaaggtcg gctgcttcaa     36720
     tgacaatcaa tcaggcaatg acaccttctt ccctggccta taccccttct aaactagcat     36780
     ctactcccgc aacaccagta tccttttatg acagcaatgc ggacattaac ttagaaagtg     36840
     ataattttcc actaaaagat aaccctagat atgccaagga tggttatcct aaaaagtgcg     36900
     gcaattcaca gcttaatcgt gtgctggata gcgataaaag acaggatttt agtggagaat     36960
     cgagaagaag aagatcgggc agtcctatct cccacatgca acaccgcaac ctgattgata     37020
     atatgaaagg tagacgaaac agtaacacga taaactcaat cttcaactac aagagtcaac     37080
     attatgaaat gccatatgat gatatgatga aaaatgaaaa cattaatgca cagtccatgc     37140
     ccttttcagt caacggtgtc aacaatgaaa atagtatcgg aggggttatt acgagagcgg     37200
     acgatgcacc ccttcaacac tctgtggtca aatcctgtac gcctgatggc aaggaagaaa     37260
     tgaataggct taaaagtaat gacagtaatg aatattccaa gtctgaaggg cagatcagaa     37320
     ccaattcgca actaagtaag gacattctca tgggtgaacc aggtgatatg gttgatctgt     37380
     cctcttttgt caacgcgcag agaaaagcct caaatgaaac tggtgactta gtctttagtt     37440
     tatcccagga tgatgacgca ctgaaaacgt tccatgcgag caacagcgca gcaacaagca     37500
     atgaaagctg gtgtattagc gatgatgcgt taggaaagca ggcgcaggac agtgaagtta     37560
     ggaggaaaag aaaatccaaa ttaggactct ttagacatat tttttcaagg aagtaataca     37620
     acaatattaa taataagtaa taaaaaggtg aatcgtaacc ttaacggcat tgattgcatg     37680
     tagttttaat aataaagtgt agaataataa atataaaatt tcaaagtcat cagaaataaa     37740
     aattgaatag acatatacat atagaaatta cttctatcat ttaaatacat atatatacat     37800
     acatgtatac gtgtatactt gtacttgtga aggactcaat agttgtattc gtttggtttt     37860
     tgaccagaag tgtttgggaa accacattcc aataagatat cgttaatcaa ttcaggtttt     37920
     tcagtaatct tggagaaaac ttcatcattt ttggttaaga tcataccaca ataacctgtg     37980
     gagttgaaac ctatcttcat ttcatcagaa aaggccttcg agcgtggaac gacacagatc     38040
     cattccttgg ttaacataag attgtaggat ttctttagtt ctggattttc gttcaaccag     38100
     tcctggaaaa aggtcaaagc tctttgcaat atggagatgt aacacatagc taataggtct     38160
     tcatcaacag tttcttcaga ctccggcatt ggcaagacaa aatgagcgaa cgagacttta     38220
     gcatcttgca aaggttcagt attgaaagtt ggtaggaaat gttctttacc attacatagt     38280
     ctatcttgga aagtgacgaa cttttcaggc atttgcagaa tttgcaaatg tttgtggtcc     38340
     aatgaagaac cactggctgg accagaattg taaaagacca tgtgtctctt gtcggattct     38400
     tcattgtcca aggcacacag caacttataa gcagtcaata aatcggttgg ggtcaaggca     38460
     tcagtttgat gttggtattc gttagttacc aataaagtgt gttcagggat tacagggaat     38520
     ttgtttaata gcaatttata cgctttgtta tcggcaccac caaattctgg gataaccgtt     38580
     aattcttcct caggtttgcc tagtggatcc tctccttctg gagtttggcc acgctctggc     38640
     ttttcgatca gacttggcat gtgactaatc aagtatggca tgctggtttt tgggtccttt     38700
     gttttcgttg tttcagtctg gataaatttt aagttaccat tatcgaaggc acttttgtac     38760
     ttgtcactaa ttaaagatgc aatgtcagcg gggatactca tttttatttt aatttttact     38820
     tttctgtttg ttctaaaatc tatctaaact ggctttcaag atcaatctat tgtcttttaa     38880
     ggtaaacttt aaattggaaa taatagtaat gttagttcct tcattttaac cttgtattgt     38940
     atttcctttg cgtgatgaaa aaaaaactga aaaagagaaa aataagaaaa tcttctagaa     39000
     cgttccgaaa caggacactt agcacacaaa tacagaatag gaaagtaaaa ggcaatatat     39060
     gaatgcagtg cttgtaactg gtgcttgtat ccaagaatag cttcttgctg taggttatgg     39120
     gaatatcgtg taagctgggg tgacttttga gctattcgcg acgcccgacg ccgtaataac     39180
     tactttcgac agaccactta tgacagtatt tcaggccgct cttataaaat gacatgttaa     39240
     caaacagttc tgattattcg ccttttgaca ggacgataat gtaaatagtt gtggtagtat     39300
     cattcaggta tgtaactgtt tactttgtat cgcttgaaaa aaataagcat ttcagagcct     39360
     tctttggagc tcaagtggat tgaggccaca gcaagaccgg ccagtttgaa tgctcaactc     39420
     ttcaaaagaa attcctcaaa tatgtccagt ttcatgtact gtccggtgtg atttattatt     39480
     ttttatttac tttgtagttc ttaaagctaa gatttttttc tttgataaat tcttgttttc     39540
     atatcctaaa attaaaggga aaataaacaa tacataacaa aacatataaa aaccaacaca     39600
     ataaaaaaaa ggatcaaata ctcattaaag taacttacac gggggctaaa aacggagttt     39660
     gatgaatatt cacaagataa aaatcatatg tatgtttctg atatatcgat atacaatcaa     39720
     acactttcaa gaatttgttt gtagactttt tgctagagac ctcatcaaag tgctaccaac     39780
     taagatcaac ttatacttct tttagagaaa atttttttca atgtactcca aagagattta     39840
     gatcctgtct cttcctcttc ctcttcctcg aaagtcaaag aaaaatcaga gtctccctgc     39900
     ttattcaggc ggagaggctc tagggtagtt gcgtttctct cattgggaca ctgaacctca     39960
     ttttccaaca ttttggtcat gtaagaggcg acaggctcat cgcaggtggg tgcatcaaca     40020
     tggtagtacc tggaccaagc gctacattga gtccctcctg gataaacacc gctacaatat     40080
     tgtctttgga cgtttgccca aaccatatct tttgaatacc aaagctggac cacattgtat     40140
     ggcctaatca ttggtgctac cataatactg gattgggaaa cagtctggtt aatttttttc     40200
     aaccaatttt tcttatctag caatgattta ataaacctga aatctaaatt gtcttcgtta     40260
     gcgtctgtgt cataatctac aattgagtac tgtgacgtcc aattatatgg caccgagatg     40320
     gggaatctgt ccggtgtttc gtcgctgtta tccttctcct ccctccaaat gcagtcagag     40380
     gcaggtgccc attcggttcg ccagtctccg ttatttacta cttggtactg ttcccaatcg     40440
     taatacgttt cctctgggtt gaagatactt gctctgctct tgacattgcc catagccaca     40500
     ccacgagaaa catcgtggaa gattacggag ctgtttacga tagcaggagc aatggatttg     40560
     acgaatgaca cttgataaaa gtctttggtc gaaaatacag tatcaacgcc gtcgtgggac     40620
     tcgacccctg gtagaagaag cagagcatct agatcaacgg tagatgctgc agaggtcaaa     40680
     gccacaaaga gggaagatgc agttacgagg tatttactaa acattggttc gaagtgatta     40740
     cagatttttc tctcttgaac cctggaattg caatagcttg gttcctattg ggaccggacc     40800
     ctcttgcgta aagtatatat ttagaagcag ctatttaaat ctgaatgcaa gacgaaaaaa     40860
     agctcgttta taggagaaaa ataccaaaaa aaggaaaacc atacacattc gggtatccca     40920
     gctttgcttg caaaatcaat cgatgagcaa gacaaacagg gccagctgat gcatatgttt     40980
     tgtgttgctt tcctacgatc agctaatgcg agtgttataa atattcccct agttttcttc     41040
     tcctccttta tgtaacaata acttgtggac ttccccaaca taagactaaa agcaaaggga     41100
     taacaaggga tttatcttat tccatccctt tgcctagcgc actgttacgc agctgatctt     41160
     atcaacaagt gtggttcttg cctctaagat ttacattgcc ttttcccaaa gggaaggtgg     41220
     gacaaaactc attttcccta aggggaaacg taagataccc tttagggaag ataagggaag     41280
     ttagtagatt gacgacgtaa atctgtgatg agatgaaaaa aaaagattag catctatata     41340
     agaaagtaca taacctccat ttaagttgaa aaaaatttgt atgtaatgtc ttttcttcct     41400
     cttttcttta tttcattctc accgctaaat cgataacggc taaaacaatt aaagctccct     41460
     tttcaaacct tatacttccg ttaaataatg caaatcaaaa acattgtcgc tgttctagct     41520
     acagtcactg ctatcaacgc ccaagttggc attgaaccta acgccactac tccaaatgct     41580
     acgcagccaa atgctacgca gccaaatact actcttccta ccgcttcggt gactacgaca     41640
     gtttcgattg gcgaagccgt agttaatacc atggcggcgg gtgcctttgg agcagcaatc     41700
     gctgccggtg ttgccttctt attctaggaa catttttatt tcctttattt ttttctttct     41760
     ttctaattcc ataaccgttg ttcaaaattg gggagctttt taactttcgt tccattaagc     41820
     tttttctttg ttctttacgt ttgattctat ttcaaccata atttattttt tcgttattta     41880
     ataattacta atatttaata ctagatgtat atacgttgtg tgtatgcgct actatagtat     41940
     agcttaactg ttttattata cccttttttt ctctctttac tgtacagaag atgcgtcact     42000
     aattcaaaaa aaaaaaaaaa aaaaaaaata taaaaaagaa agattttgga gaagctatat     42060
     ccttttgtga catacaatag agaaacttgt tctgttggta agatatctca tctgaaatac     42120
     aacaaggaaa accaaaagcc attttttcat tacttgatcg acttatgaac cgtattacta     42180
     ggaaaagttg tttattcgcg attatatttg catcattatt tgtgacacat gcattgggtg     42240
     ccgctattga tccgccaagg cgaccacata atgtgaagcc ttttcataac ggtaatctcg     42300
     aacttcaaag aagagcaaat gaaccgtttt ttgaaataga tgtcaagagt ctgaacacaa     42360
     actcaccgat atcagagttg tgtaaaaaag atttgcacgt cattgaatcg tctcatgatc     42420
     tttttcattt acaaaaccaa tgtgaattca tcttggggtc attaaaagtc acaaactatg     42480
     attctaacat tttggatttg aacagcttga gggccattgg tggtgacctg attattcagg     42540
     attcacctga actgatcaga atccaagccg ggaacttgaa taaaatcgaa gggctcttcc     42600
     aattacaggg actaacctct ttggtttctg ttgaaattcc aactttgaaa ttttgtcagt     42660
     cactggagtg gaaagttgtt cccatcttga actacgtctc catggattct cagaatattg     42720
     agattataaa ggatattgtc atatcggata cttcattagc aaacatcgag aatttcaaca     42780
     aggttcagga aattgatact ttcaatatca ataataacag atttttagaa actattcatt     42840
     cgaacgttaa aaccattagg ggacaattca gtgtacatgc gaacgctaag gagctagaac     42900
     ttgaaatgcc acacttgaga gaagtggaaa acataacgat tagggacaca tcattggtct     42960
     accttccaca attaacaaaa gtgaaaagct ctttagagtt catcgaaaat tacttttacg     43020
     aattgaacct gaacaatttg cagaagattg gtggaacatt aggaattatc aacaatgtaa     43080
     atttaataaa agttaatttg gagaacttaa cagacattca aggtggcttg atgatcgccg     43140
     ataacgaatc cctcgaggat attactttcc tgccaaactt gaagcagatt ggaggtgcta     43200
     ttttctttga aggttcgttc aaagatatca tgttcgatag cttgaaactg gtgaaaggta     43260
     gcgcttttat taagagttca tcaaacgtgt tggattgcaa taaatggaca aacccatcaa     43320
     atggaagatc aatcatcagg ggtgggaaat tcacttgtat ttctggtaag aaggaaaata     43380
     cgctgaatgt taaacaggat ggtacaatca tagaaaaagg gtacaaagat ttaacgcaag     43440
     aaggtgaaga ctccaagaaa agagtgattt caaaatacgc gaactcagca aatccaagca     43500
     tgcaattgga cccccttctt tttggtacat gccttgttgc tatgttattg ttttaagatt     43560
     actagtctag tataacagaa agtttttttt gttcctaata ttatctttat ctatatacat     43620
     atatctccat gaaaggcatt tgaatttcta tctttctctt tcaatcaaat attgtcttat     43680
     tattgatcaa ataatcgtat atgcacaatg gcaactcgtc tttcaaactc tccacttgcc     43740
     cattcttcag tttgttccta atctcggatg atgaaacatt tcttaatgct ggataatcat     43800
     tttgcataac atgaatccta gcgccccatt ctcttggtat taccggttcg aattttccct     43860
     caaggatgtc actggcgtat cttagttgcg attcagcact gagatggcaa tcgcctctcg     43920
     ccaagcaata taattgagat cccgacatga agctctccat tacatcactg atttttaaag     43980
     gatgataata tttttcatca aagatcctag caattgtatc aaaaccaact aagtagccta     44040
     tatctgcact gcatccttta acaaattgct catgtaatat tttgtccttg tcgatgaatt     44100
     tcgagaaaac agtcaacccg acagatacta cagattgggg gagcttctcc tgaaggtagt     44160
     cagcgaataa gcacatcatt tccagacgag ttggaaaaga tgccggctta ggcaacttat     44220
     ctgcattatt caccgctaac agtaataaaa catgcgaacg ggtgtccttc aatttgaagt     44280
     ttttaatagt ctgcgatagt agttgaaaat gggccagatg tggtggattg aatgaagaat     44340
     caaggacaaa taacttctga cattctagat gctggggtcc tttgagaacc tgaaatagta     44400
     aattgctttt tcgaaactgc tcgaacgtct tcttcatatt agtctgctag tgcacgtact     44460
     gctatcaacc gtcattgatt aagtgtccat tttccaaaga agtaggagat tatataacca     44520
     cgagtatgac gtcttccagg gaaaaaaaaa aaaaaaaaaa agaaagccaa aataaggagc     44580
     cttgaaatgt gtatctgata tatataatgt gtatgtaaat atctatttaa ttagccattg     44640
     ggatttcaac ttcttgtttg aaacagaagg acggataaaa tacgtgatca ccaacaagac     44700
     gaatatagta ataagcaatt tacccttttc gaaagtagga ctcattaaat caaattggcc     44760
     cgaaggtgtg atccttgtac aaaatacatc aaggcctaga tcacatataa tgcttgtgga     44820
     ttccagattg gttgggatgg agatcaactg cgaatcggat cctggcaata gatttctgaa     44880
     atgagtgata atgaaattat cattaattgg gataactggc gtgtatgggg tagccataaa     44940
     ctcttttttc ttatccttgg ccatttcttc tgctggttta cctcttgcat tcaataaaag     45000
     ctttggtatg taggtgattt gtccattttc taattccata acgattgcct ttgtggtaat     45060
     atcatccgtt gtcttggaaa tggacattgt tttgataatc tcgggaaaaa tgaattgttt     45120
     agtttgaaat tgaggtttgt taatgtgtcc agtcaatgga tcataagaaa aattgtcgct     45180
     tgagttagac aaacgctcat ctggggttag tgactcatat aattccacca ctactaactt     45240
     ttgttctgga acaggttcag aactgaaata ggaataaacg acccaatatt caccgaaaac     45300
     aatatccatt ggaaacctaa aatccggaga atccttgtgc tcttgggtaa tgaggatttc     45360
     tcctgtaatg gtatcaatta agttaaaagt gattgtatga tgttcttcat tagcgatcag     45420
     ataagccgct aggttggggt acaaatattt ataaagaacc gatttgtcac ctagtgtaat     45480
     accaagagtg tttaggtttg ttgtttccct cttgctatat gccaccattt tctctttcga     45540
     atttacggct tttttccaag tttgttttac cgtatcgttt tcgattatgt agccataaat     45600
     gccattcgtg tcatgctctg tgacgaatat gtgggaacta gaatggttgt tggcaactat     45660
     tggtacatcc gtattcttgc cgggattcaa tttgaacagt aaatgatcct tatcctcaaa     45720
     cttaatcaga tactggtgat catgttcatt cagcctaata acggaatcaa cagttttcct     45780
     ttcagatagg ggggatcttg atttgataat cggttgatct ttagtaactt caattgtcaa     45840
     ataatgccca tcatgcgaaa aaacaacaag ttcgtcatgg tttttatccg tccagaacat     45900
     tttgacgccc tgatcaattt ctaaatcgag tttccagata agttggccct tattgaccat     45960
     atcaaggccg ccgataaagc catcatgcgt caaaacaatt aagattttgg cgaatccgaa     46020
     cttcaaatct gataccgtgg tatccttagc gtctagagct aggagtttag tgaagacacg     46080
     tcctggtgag aattggtttt ctttcaataa gttgataagg cgattccaat tagttgtcaa     46140
     tctaagccag taagcattcc aaagcgaatt tgaatcaagt tccgctttca tatctttgtt     46200
     caactccaca tccctagaat cgaagacgtc caatacagca tagtctacca cgttagtcaa     46260
     ccattcatct ctttgccaaa cggggatcaa ttctgtgcca ttggcagaga atcccatata     46320
     ttgggtatca ttaacgttca acactaacgc caggggatct tcacgatgaa aatattccac     46380
     tttattgaac ccttgaggta actccaattt ccattctgcc agttttgact gctcatcgag     46440
     aatatgtagt tcattgttct taatagatac ttgatcgttt aaatatgagg attgaggtaa     46500
     aatggtcgta gaaggggcat tatctacgcc ttcctctagt aaaaaccaat cgtgtaaatc     46560
     atatttctgc caatggttgc ttgaagagtt cacacaaacc attgcgttat ggtcattact     46620
     atccagttga atctcatcaa tggtaaaggg taaaacgttt ctgaaaagaa tctgtccgga     46680
     agaaacgtta aacgaagaaa ctaagcagga agtttcggta gggttcgata agatgagaac     46740
     cctgttgcgg tctcgagaat cagggatgac tttctcccaa ggacctaagt tagccagttg     46800
     ccaatcagtg ataaatgcat catctgaaaa aacggcttgg acacaactcg tgtttaggaa     46860
     gagtaaaatg aagacgtaca ccaagtctgt acacgttatc ttcattgcta tgggggaagg     46920
     ggaggatgaa agtgttgata tgaatgtagg tattagttat taatggagtg tatatatata     46980
     tatgttatta tatatttgca tatataatat gaaatcccag ccatattttc tctggtagcc     47040
     gtctgaaaaa tcacggtgta cgaagaagga tttaatatac gcacggtaca actaagcaat     47100
     ccgcaaagac ctaatgtgtc ttttcattag tgagagcctt gggggtaggc cctggtaacg     47160
     gctggtccgt gctagtgggt gtcttggtat gggagggcat ggtagttggt atgaatttga     47220
     tgcttagcga agtttctaag gccaaagtca tccatggatc ataaagcgat cttattgtat     47280
     cgagatcaat atcttgcggg cctttcgtgt catggggcaa aatgacacct cgggagagtg     47340
     tggtgctgga tctcttcttt actggtgcgg aaatggaatc tcccgaagat gctaagaaat     47400
     gcagtctttt ttccacattt tgtagatgga gttttttgga ctcggaaaga ccttcaaggc     47460
     cagtagaaga agactgcgga ttgtgggata tggaattgat gagttcaatg gaattttctc     47520
     taatgtttct tttattttga aaaaactcga acatgtccaa gtgaaattcc atgcgattga     47580
     ggtactcgtt gaaagacatg ggcttgtatt ccaagggtcc gaaccattta ataatgggat     47640
     tctgcgcctc aacttgcgct ctagcgagag cgacgctttg tttgacctca gggatatttg     47700
     tcgagagagg agtaccgttc atagcatcct tgacttttat tttggtgggg tctatgccct     47760
     cgtgataata tttgacaata ttgttgaaaa acttcttgtc acgtacggat ttcatttcgt     47820
     cgcaccaggg gtcgtattta agaaagttca ggcgagtaag ctccaacagt gactgagaaa     47880
     gtagcaaaga gccaaacaac ccccataaga gctttctgac gctgacgaat cgagattggc     47940
     gaggtatgat gggaggaggg gcgagcacaa tgtcaccatg ggtggtggag aagcggttca     48000
     aagttggaaa gtcagcaata tcctttttga ttttagtctt gccattgaca atcatttcac     48060
     tgggtagttc gccaaaggat aaatccgagt gagtgccagt ggcaatgcgg cgcggtggcg     48120
     gtagtttgta gagccttctc agtctccaaa gggcaaagaa acccactgca gattggatag     48180
     tgattagagt gtatagtccc ggtaggttat caggagcggg tacgagcgga ccccacagtt     48240
     ttaagcctaa acttggcctt atgtagaatt tcttgatatc attatcatct ttgtcgtggt     48300
     catcttgtgt gtgagtatgg tcggtggaat tgctattacc tgatggagga gtaaatacag     48360
     ccatctttta ttacggtaat tggaaaagga gagggaatgg aggaggatga gataagtagt     48420
     ttcctaagca gtaaagcaag tgtccacatt taagtaaaag acgatgccat gcacttatta     48480
     ttactacgtg gtcaattttc tctttcccta aggcgttcgt gcagtgtgac gaatatagcg     48540
     aacaactatt gtgtttgaat tttaacgttt atctttttat gattttttta aaaaaacttc     48600
     ctagaaaatt tcttatatat ctctatttaa tgaaaaacca aagtgatcag aattacaatt     48660
     catcgtgaat ggcatcttct tcgtcagcca attcagcgtc agcatcggct tcctcagcag     48720
     ctttttcctg ggcttcttcg tacaaggcct taccgtcgac gtcgaagtga ccgttttcct     48780
     tgatgaagtc gaataaagag tccaaggatc ttgaaccttg gtacacaaca gattcggact     48840
     tcttaccacc tgggtataag acgattgttg ggtaaccttc aattacgacg cctctgacat     48900
     cgttttcagt gtggtctagt ttagcaatca aaacgtcgga tgtggcgttg gcgtaggtat     48960
     cagctagttc ttggtaagtt ggggccaatc tcttacagtg accacaccat ggggcatagt     49020
     acaaaacaag aacgtccttc tttgggtcgt tgacgatttc gtcatggttc ttaccgacca     49080
     attggaagac agaggaatct tggttctcga agatctcttg ggacttcacg attggggagg     49140
     catcaccttt caagaagtcc ttaaccaaag attcaatagc cttagactcc aacacgatct     49200
     tgtcgctcaa ttcgtcaaac gcctcttcag agagttgagg caaaccgtac ttcaagtctt     49260
     cagtcatgtc gtggatggca aatagaggga attgttcctt catgttcaag ttgccggcgt     49320
     gtctgccgaa ttttctggca tcgatgctaa caaagttcat tagacctctg ttctttttgg     49380
     ccaactcggt aaagagaggc ttgtattctt ccaattcttc ctcgtcattg tagaataagt     49440
     aacccaaagg caaaccgctt tcgacgtatt gggcgaaaac ggaaccgtcg atttcaccaa     49500
     agtagggcaa ggcttccact tgcaaccatt tttcaaaaac atcagcgtca gcgatatcgg     49560
     ctttcttacc gttgtatact acaggctcgt ccatggcgga gggcaagtaa atagaaagct     49620
     tgaaatcatc gtctgcgttt tcagcggaga caaagtcgta gtcgttgaag tgtttgttgg     49680
     ccatggagta aaaggtggcg ttgaagtcgg cgtcaatctt accggattgg acgataactg     49740
     gagtgacaaa agtctcgtta gcaaggtaag ctggtagatc agcaacaacg gcgacagccg     49800
     gttggctttg cttgatcatg aattggacaa tggcctcggc agttctaggt ccctcgtaat     49860
     cgatcgagtt gttaacatcg ctgtttttga aaatcttcaa gcttgggaac cctggaatgt     49920
     tgtgttccat acacagatcc tggttttcag tacagtcgat ctgggccaag gtaatgtttt     49980
     tctcaactaa agtctcggcg gctttaacgt attcaggagc catgttctta cagtggccac     50040
     accatggagc aaaaaactcc gcaagcacca agtcgtgcga ctgaatgtac tcattgaagg     50100
     agtcggtggc caacttaacg acagcggagt cttcaggggc cacagcctct tgttgggcga     50160
     aaacagagga ggcgagcagc agggaggacc atgacaggac ggcaccagca gaaaacttca     50220
     taacgggata gatgtatgtt tttctttatg tagagcttgg cagctttaaa attaccaatt     50280
     agacatgctg cttgcaacaa gaaaatgcac gcgtaacaaa atatatatat atatatatat     50340
     atatatgtat gtccatacgg gtttttcgtt ttgttgtggt tgtaacagca caacaaaatg     50400
     ctacacggtg gcaaattgga aaaagagact agtgagagaa aagggaaaaa gaggcgccgc     50460
     ccgacagggt aacatattat cacgtgcagc ccaggataat tttcaggaca cgtgtttcga     50520
     aaggtttgtc gctccgaaaa aatcaaaaaa aacaaaaaac gggaaataac aataacgaca     50580
     aaaatggaaa aaaaaaaaat tttagacgcg gcgcttgcac cccgcattat aagtggtgtg     50640
     ccgacggacg gtcaacccct ttcagggggc cccctatctt gggcgtggtg tcacaccacg     50700
     ctcaaacggt gggcactaat gaaaacgcgc ccatataaat atccgctatc aacagaaccc     50760
     ccaacccccc catcagtgcc caactcagct tccgtaaacc acaacaccac cactaataca     50820
     actctatcat acacaagatg tcattcgacg acttacacaa agccactgag agagcggtca     50880
     tccaggccgt ggaccagatc tgcgacgatt tcgaggttac ccccgagaag ctggacgaat     50940
     taactgctta cttcatcgaa caaatggaaa aaggtctagc tccaccaaag gaaggccaca     51000
     cattggcctc ggacaaaggt cttcctatga ttccggcgtt cgtcaccggg tcacccaacg     51060
     ggacggagcg cggtgtttta ctagccgccg acctgggtgg taccaatttc cgtatatgtt     51120
     ctgttaactt gcatggagat catactttct ccatggagca aatgaagtcc aagattcccg     51180
     atgatttgct agacgatgag aacgtcacat ctgacgacct gtttgggttt ctagcacgtc     51240
     gtacactggc ctttatgaag aagtatcacc cggacgagtt ggccaagggt aaagacgcca     51300
     agcccatgaa actggggttc actttctcat accctgtaga ccagacctct ctaaactccg     51360
     ggacattgat ccgttggacc aagggtttcc gcatcgcgga caccgtcgga aaggatgtcg     51420
     tgcaattgta ccaggagcaa ttaagcgctc agggtatgcc tatgatcaag gttgttgcat     51480
     taaccaacga caccgtcgga acgtacctat cgcattgcta cacgtccgat aacacggact     51540
     caatgacgtc cggagaaatc tcggagccgg tcatcggatg tattttcggt accggtacca     51600
     atgggtgcta tatggaggag atcaacaaga tcacgaagtt gccacaggag ttgcgtgaca     51660
     agttgataaa ggagggtaag acacacatga tcatcaatgt cgaatggggg tccttcgata     51720
     atgagctcaa gcacttgcct actactaagt atgacgtcgt aattgaccag aaactgtcaa     51780
     cgaacccggg atttcacttg tttgaaaaac gtgtctcagg gatgttcttg ggtgaggtgt     51840
     tgcgtaacat tttagtggac ttgcactcgc aaggcttgct tttgcaacag tacaggtcca     51900
     aggaacaact tcctcgccac ttgactacac ctttccagtt gtcatccgaa gtgctgtcgc     51960
     atattgaaat tgacgactcg acaggtctac gtgaaacaga gttgtcatta ttacagagtc     52020
     tcagactgcc caccactcca acagagcgtg ttcaaattca aaaattggtg cgcgcgattt     52080
     ctaggagatc tgcgtattta gccgccgtgc cgcttgccgc gatattgatc aagacaaatg     52140
     ctttgaacaa gagatatcat ggtgaagtcg agatcggttg tgatggttcc gttgtggaat     52200
     actaccccgg tttcagatct atgctgagac acgccttagc cttgtcaccc ttgggtgccg     52260
     agggtgagag gaaggtgcac ttgaagattg ccaaggatgg ttccggagtg ggtgccgcct     52320
     tgtgtgcgct tgtagcatga tctttttaca tttttttggt ttgtgtacgt atcccaccgt     52380
     acttaccatc ttctctcctt tatatatata tatatatatg tatattttca gtgtatatac     52440
     atacattctt atacaatacc gtataagaac gtatgtatgt atgtatgatt ttctcacatt     52500
     aatgaacaat atcatcggaa acgggccttt ggtttttaag ggaaaatgaa gaacaataaa     52560
     tgccttgcta ggtcttcctt tatcattttt ggaagtcaaa tatgaaaaac acttccaagg     52620
     gggcgtacta cttcaactaa taaaatgtca cacactaata agatcgcata cgtgttgaac     52680
     aatgacacgg aggaaacagc ctcgccctct tccgttggtt gttttgacaa gaaacagctc     52740
     actaaattac tgatacatac tctaaaggag ctgggctacg actccgccgc taaccagtta     52800
     ctgctagaga gcggcggata tcaaaatgag tctaaccaca tccagacttt cttcaaactc     52860
     atcaagaccg gccaattcca tcttattaat tggcagattg tttgctcgct gccccttgcc     52920
     catagctctc cgctaaggtc cgaatggctt caaaggctgc tcattcccac gccgacgccc     52980
     gccacgactt cacttttcga ccacatgctc ctgcaactgc aatacctgca acagctgatg     53040
     agctctgtaa attcatctac ttgttcggac gcagagatcg ccacgctcag aaattacgta     53100
     gagatcatga ttctagttaa tagacaaata ttcctcgaat tcttccatcc agtcacaaat     53160
     tccgcctctc acaagggccc tcacactgca ctgcccgtcc tgtatttgcg caaaatcctc     53220
     aaaaacttca tcgagatatg ggattccctg ctggtgtcta acgatcagtt cctaaatgaa     53280
     gaaaacatct tcaatccgga aacgaccttg agagaactgt cgacgtacct gaccaaccca     53340
     aaactaaccg cgcagttgaa cctcgagcga gaccatctga ttgacgccat ctccaaatat     53400
     atcgatccga acgaactcgt tcccaagggt cgtctcttgc atctcttgaa acaggccatc     53460
     aagtatcaac aatcacaaga catttttaat atcatcgatc cggatgatga cgcctctttc     53520
     tcctctccac cccaccggat caaccttttg caggataact tctcacacga tctgactgtg     53580
     acctttcaag aatggaagac tatccaagac accacagacg aaatttggtt tttgacattt     53640
     tcgcccaatg gcaagtattt ggcttctgcg acttccgagt cttcaagagg ctacttcatt     53700
     actgtttatg atgtggaaca agacttcaaa atttataaga cttgcgtgag cttgtcacaa     53760
     tccgtattgt acctcatgtt ttctcctgat agccggtatc tggttgcttg ccctttcagc     53820
     gaagatgtta ccatttacga catgaatgcc acctccctgc ccgatgcgtc tgccacagac     53880
     tcgttcctac tatacccttc taccaggctc tcgcccatgg actcgtttaa actggacacc     53940
     accacgtacc cagatgatac cgaatcatca gcatcatctt cctcgaggcc ggcaaacgcg     54000
     aattctaatc aatcaagagt atggtgctgc gatgccttcc acactgcgga acgtgcgggc     54060
     tggatggtgg ttggatcgcc cgacagagaa gctattgtac actcactcac cacgaaagag     54120
     tcacttttta gcttaaaagg caggacttgt atcgcgttgg gccacgatga aaacatctct     54180
     gggagaaaat caatcgatcc tgcaaaagtc ctttacaaac caacaagtag caatggtaac     54240
     tggcaatatg tggaggacga cgaaaccttt ccacgtgtgc acgacgtgaa aatcagctat     54300
     gacgataaat acgtgctttt aatgacccac cagggcgtta tagatgtcta cgatttcagt     54360
     gggttcccct ccaaagagga gctatctaag caaacagtgg atcccaaaaa ctttctgatt     54420
     ccaaggatcg caagattgga cgtgggcaaa aacatgactt gtatctcatt accgctaaat     54480
     accacgcatc aaggcttcca taggcaacaa atatccgagt ctcaacattt ggtattagtt     54540
     agccttcaag ataacgaatt acaaatgtgg gactataaag aaaatattct catacaaaag     54600
     tactttggac agaagcaaca gcactttatt atcagatctt gcttcgccta cggtaataag     54660
     cttgtcatga gcggatcaga agatggtaaa atttacattt gggatagaat tagaggtaac     54720
     ctagtatctg ttttatccgg tcattccacg gtaatgagta attccacaaa acccatgggg     54780
     aaaaattgta acgtagttgc atcaaaccct gcagataaag aaatgtttgc ttctggcggt     54840
     gatgacggta agataaaaat ctggaaaatt tcaagaaatt aatactccac cttatatata     54900
     tacgtaagca aagttttatg taacaaaaaa aaaaaaagaa ctaatccaac cttctttcac     54960
     tttcaggtaa aacttgactg agttcttcag cctctcttct acctctcttg acatccaaac     55020
     agtttagcac aggcaatgat agcatcaaaa gcaaaaagaa gaaataaaac gaatagcgaa     55080
     tattatgcgt tttatcggta agcagtccaa caaggaaggg tcccaggatg gacgacccct     55140
     tatctgtgat actgaacata ctaaaaaacg tggattcttt tcctggaggt acaatcaaac     55200
     tgaaaactga tcttgaaacc gcggacaggc cacctagtga taatccatac caaatggcca     55260
     ataagaacat ttcaaactta tgctttaaac cgaacgcatt gaagaaaaat ccaagaatac     55320
     cataaaatgg tatgaaactt gcccaaatga taatgtacat caaagtttga ctagaagtcc     55380
     accgaaactt tgtggcaaga aattgtggaa tcataaaggc acccagcatt gcatttacaa     55440
     cggtcaaaac acttatcatg attaaattga gggtactcat gtgcagttct gccttggaga     55500
     acaaaaccgc tgtagaattt atagttgtaa tggaatcact aataataaac cacgcaataa     55560
     gaaaaatcat cacatctttc aatagtctgg catgtttaaa cgattcgaaa agcgaaaccc     55620
     aaccatatga aaggtaattc ttccagttta gttgacccaa ggcgtcttgc tcaccgggat     55680
     acggactgcg ggcggatgct aatgtagaat cgtcaactct tatcggtatt gtcacatcgt     55740
     caatcaacca gatcatgggc agttgccaca caaaccacca aatcccaacg aaaagaacag     55800
     ccacttgaac atcctgctta ctgccctttt tagatgcgac taagaacata gatacaatct     55860
     gaacaatgag ggcacttgaa taacctaaag atgcacctct accgctaata acagtagtta     55920
     acgagtctac cttatcaggt tcataagctc cttgactttg acatttcaaa gaatccttga     55980
     caaaaatggg cagaagagaa ttcccaacaa cattgataac gccaaaacaa ccattggcca     56040
     ctatataaag cccagccaga gaataaatct gggtatcatt caattttgaa atcgcaacag     56100
     tcgacaatgc gcccacaata ccaaaccaaa ccagaattct gcctttgaat ttaacgctcc     56160
     cccagagatc tactatccct gaaacggaaa tgactattat agtttggaat aaaacgctaa     56220
     gggaaaagac atataatgca aaacttgaag tatctacgaa gatccgattg ttgaacaaac     56280
     caagaacaca cttatctgaa tcactacccg tttctgacag gcagggtatg gagtgatcgt     56340
     gaacttttac accatttata ctcgcaaatt gctgcagtag taagggaata tacgttgaaa     56400
     ccgcagaaac gacaaatggt tcgctagaaa atgagtaagc gtaccatccc ttgatattgt     56460
     tttgggcttt ttttattcga tagttcgtta ccgattcatt catatcattt atagttccat     56520
     agctcatatc taatgtagag aatatgttat gagcaaacta ttgcttataa gggcaaaaac     56580
     cgtggtaata taggtacagt ttgaaatctt tccttttgtt tacactacgc atctttcaat     56640
     agctgaggta ttttcgttta ggaaaatacc gttttaagga attaatttta gcaatttcct     56700
     aaaattgttg agcggcgcta tcaatgccgc acaatacaac aattaataat ctaagacacg     56760
     ttgcattata catgacagaa gctaaagcat ggtcttagat gacaataaaa aggaatttga     56820
     cagcacaaaa gagaaaaaaa aaactataca taaaattttt tacatatgaa ttgcttagag     56880
     taaaataggc atttttcata tcttcttccc aattattaaa ttagcaaaaa attgaataaa     56940
     aaaagcaggt ggtttaagaa ttgcgcaggg agaagaaaga atatcatatc tcatgatggt     57000
     agccacttag acagagagaa aacgaagtga gaagaggcta gtatttttat atcttaaaaa     57060
     aaaaaaaaaa caaaaaaaaa aaaacataaa tatttgtatc ttattgctta tgatgataat     57120
     gtacaatgaa ttcaaaacat gaaaattgtt caaagttttt atttttattt tctctttcgt     57180
     attaaactga tggaacaaat gaaaaaaatg gataaaaaaa caaaaaaaaa aaaaaaaaca     57240
     aaaaaaaaac agctttgctg gaggatgatt aacttttaat ttttttaatt attaggtttt     57300
     tcaatttttt atggtttttt gtgtaaaatg caatgaacga atccattttt tattttgcaa     57360
     gtgtgagagg cctttataag gaagactcgg attcaccggc agcaaccggc gcagagtctt     57420
     ctttggtttc ttgttcttga gaagcgagtt cagtggatga ttcctcttct tgttgaggaa     57480
     caggtggtag ggatatcatg aattggtcca atgcatcgcc gaccagttct ttttcaatat     57540
     taatttcagt ttcaaaagtt tctggtaacc agtttgacca gctcttggaa cgaacgaagt     57600
     acttatccaa tggagatggt tctttggctt caccggtaac gttatcacct tccttggcgg     57660
     ccaaagtacc ttctgcaaca ttgacggtag cggcttcgtt agcgacaatt tctctcaatg     57720
     cggctaaaat caggttagtg tcacctccga aggacatgtt aacaactctg taaaacttag     57780
     agattaaaga caatggagca aaaccatcct tggagagttt ggaccttaag taattgtcga     57840
     cggtcaagtt ttcttcgctg aaatagtatt caatttgtct agcaatgttg ttgatggcca     57900
     ttaacactgg ttggactgga taaaactgtt gctgtaattt gaccataggt tgttgaggat     57960
     gttgttggtt gtgatggaag tggttgtggt atttagagcg gttgttgttg ttattacgag     58020
     cgttgcgtcc ttggtaaggt ttaaactgtg gtgggaagcc ttggttctga ggcataccgg     58080
     cgttattact gttgtggaac tttctccttt gaggaccatt gctgttatgg tgatgactgt     58140
     ggtgatgatt acggtggtga ggtggttgtt gctgttgtgt agattgacca ttttcttgag     58200
     aggtagcgtc ttttgaatct tcctcaccta ctgccgattc aaagccatct ttcttcattt     58260
     gttgttgctt cttagcatta tgttggtgat gcttcttttt cctgttagca ttactcgacg     58320
     atgtcgacga tgctgcagtt ttgttgtttt tgctcttgtt gctgttgcca ttacttgcac     58380
     cattcttgga accggatctt ttggtgccag agacggtaat ggaggccttg atgggaaccc     58440
     acttggtagc agtcgatgat ttcggagtgg gtgttctgtt cttcttcttt cttgtggcat     58500
     ccaagtcttc tattgagata gtagaaacag ggatctcagt aggagcaagt ttccatgggg     58560
     aagatgtggg caatggtgcc ggcgtcaagt tgacttgctt gctcttggag ctctcttgtt     58620
     cttgcacttc tgggactggg gcagtagcag tgtttgcggc ggcggtttca gcagacatcg     58680
     tgggcagaga agtgaaaaga agatgaaaca cgttagcagg tccagagtaa tcctgatgtt     58740
     ctattaccga tctaggatcc caaaagatct tcataaaacc gaaaaagatg ttaagaaatg     58800
     tttacacttg tacttttctt tctttgttct tgacctacca gaagtgaaaa aaatttttca     58860
     ttgcgtgggt acatccgtgc accatttctg aaaaatttgc gatgagcatc cctcaaaatc     58920
     cgtattatcc gctagtgttt tgaggttcaa caagacaaca tataagaagg gaagaaggaa     58980
     aggaggcaat gagaacttgg gtcttgctcg agagtccaga tccacatgca ggttcaaaaa     59040
     atggtgagag ataacagtaa taacggtagc gataaaagcg tccattggga gaggaggaat     59100
     aataacggcg caggcccccg ttatcgttcc agaagcggta ataccggtgc tttggcaaca     59160
     aaactaagta atgggacgct ctctgtcaga ggattagtga aggaccgaac aggaagcggc     59220
     aagatcgcgg gctgtgtgga ggcgtttctg gatgccagga cccaattgaa tacgccctgg     59280
     gaccgtgcta agtgcaattg gctggaccag atagattact atgtacagtt gagaaagacc     59340
     gcgttttcta aggaattgga ccaactaagg aagcccatga tcgatgcata tgtggcggag     59400
     atgaggcaga agtttgatgc ctcctatgga caatccaggg cgcaattgga agccaaactg     59460
     gcgcaggtgg acagtgaatg gcatatggta catggtgatg tgcatgcaaa actggaaaaa     59520
     ctcgtggaag aacgccggtt tttgaaaaga ttaagcgaca cgatcgtacc acccaggtcc     59580
     aaaagatcac agcggctgtc tccattgacc aaagaggacc gagccaactg tatctgtccg     59640
     cagcccaaag gaatgagcga caccgcttgg ttcgaagcca ttcagaagaa aatgttagga     59700
     atgaatggta ccatcaagct cctagagaca gaacagaaac tactggctga cgagaaaaac     59760
     agcgtgagga agacgttctg gcccatggtg gaagcacatt cacgctcgaa tgaatttgct     59820
     tatctggaga aatgcatcag gctgatggcc tctcagagag caatatgctt ttgtcttgat     59880
     atagaggctt tcgaaacaaa ccagaacgta atcaccgaaa ttgggatttc aatttatgac     59940
     cccagggaaa atatggtgcc gtcaatggtt ccaattacaa agaattacca cctaattatc     60000
     gaggagtccc tggaacttag aaaccaaaaa tgggtctgtg actacaagga ttgctactta     60060
     ttgggagaaa gctatgtttt gagcttgaaa gagtgcgtgc atttcattca atcactaata     60120
     aactattact tggtcccggt gaccgaagaa gacaagacat ggtcaagggc atttgttggt     60180
     catcacgtga gcggggatct taagtggctg gagactattg gtgtcaaatt ccctggcaga     60240
     gggtatgaag gccatctgga ccatacgctg cttttggctg aaactcccgg tgatctagac     60300
     gtgttcatct tggacactga gcagttttac aggaaatcgt atggcgaaaa gggcagcagt     60360
     ctgggcaaga ttctgcggtt gttcgagata ccgcatgcgt ttctacacaa tgccggtaac     60420
     gatgcctact ataccctgca tttgttcatg aagttttgcg atgttaattt caggaaaata     60480
     agcggcatgg acgatgttct taaagtaatg ggccaagtaa aagtttgggg agaacgagac     60540
     gtacgagagc ctaaagtggt gcccatgtcg tatgccatct ccatcgagga ggcagtcaaa     60600
     aatcggacgt accgcaaggg cgtcaagagc agtaggaagg aaagagtctg ccaaacggaa     60660
     ttcggtgggt taacgtattt cggaactgct aaagacgcct tcacaagcac tcttccgaca     60720
     cactaaatat attcatcgat ttttttcctg taaatacaaa cacatgcttg tatacatata     60780
     catatacata tatataagct cattataaac ctgtgtgcat ggaaaaaact ttgtctgccc     60840
     ttaatttgca agaataggtt ctaacaattc ctccaattca ccagtctccc tcaattcctg     60900
     caagtcgtcg ttgcctccaa tatgtttacc attaatatag atgtttggca cggttctttg     60960
     gccattaatc tcatataacg cagcctgaat gtctgcgcct tccttcatgt cattcaattg     61020
     caaaaccaga actttggacc tgggaacctt taacttttca aaaagcgtgt ttagggctgc     61080
     atggcagtat ggacagtacg ttttggatgc gacgaagatc tcgttttctg caataaggtc     61140
     cttgacgtgc ttgatagttt cttgagatac catttttttt ccttctgagg ttttgtctat     61200
     ttgtataatt atgcgaatgc tcgtataagt actgcacgaa gttctttatt ttatgctaaa     61260
     gtcccttttt atattatata aacttttcat ttattttata tatttactcc tttcaagaca     61320
     aaattcccac atcacgtgaa tcaggaggcg caaggggggt agtaaggcag tagtagataa     61380
     agaaaacaag catcgcaatc tggaaacgcc gttgcggctg ctcgttatct gtagacagct     61440
     cacttgtgca tgaagttcat gttttataga tgatggagcc atacttcaag gtgataacta     61500
     tgaaactgtt ttgaccttga cgtgtaaagt gatcaaggta atagttaaac tttatatatg     61560
     ttgtttatca atgtggtatc ctttctaagg atgaagacaa cacgattgtg acagtgtgag     61620
     agagtgataa agcattggag gcaggcaaaa caagaacatg gggtttcttt cggatcatcc     61680
     gcatacagct atcaccgaga cgatctttcg aattgtctct tcaagggact atacgctaga     61740
     agtggagtta gctcccttga ttcagcttat caaagcagat cacaacgatt ataactatac     61800
     cgtgaaccaa gaagaagctg cgcgagcact tagaaagaaa ataaagtatg ggaaccggct     61860
     gcagcagtcc aggactctgg acctcttgga tctgttcatc tcacaaggcg tgaagtttac     61920
     agtcatgtac aatgatgaca agctgctgca aaggctgaga gggatggcta cgaactctga     61980
     aaacagcggg tccggtgaaa agtatgagcc taggattatt aagaagtgcg cggcgtatgc     62040
     tatctcgtgg ctaaactata ttacgcagaa caaccttgag aatgcgaggg cgtattcagg     62100
     tctttatcaa ttgggtcaaa cagtcaaaca gaggtactcg aagagcagcc gttcccgccg     62160
     tagcggcgga ggctctggcg gacggtctaa cttcatggat gatagcgccg acgacacttt     62220
     gtaccagtcc aactcgctga ctagtgccga tagattgtat aggattccac agatcaacat     62280
     gaacaaagag gcacccagga ttcggctcat aatcagcgat gctctcgcgt ctgctgtgtc     62340
     gttacagaac tcgctgatcg ggctgcccaa gggcaagttc tccacagacg atgaagaggc     62400
     cacgtccaag ttcatccagg caagggcgat cagaaggaaa gttcttagat atctgcaatt     62460
     ggtcacggag ggtgagtttc tgggtagctt aattcatgcc aatgatgaac tggtggctgc     62520
     gttgactgca tacgacgacc gaagcgctca ggacgatagc agcgatgaaa gtgatcacgg     62580
     ctcgtacgat gacggtattt atgatgaaaa cgagcaggat aacagcaggt atattgatag     62640
     cgagtcctca gaggaagaga gcttgtcttc ttatcagccg tccacgatct caaacccttt     62700
     cggtgatcat aacaaaattt gaagaagtat gtacgtatgc atacacacat atatatatat     62760
     atatatatag tacatttaat ccttcttgag gtttaaagac gcactgttca cacagtgtct     62820
     ggtgtccttg ggcaagttta gcaactgttt ccagccttca ccttcaaaca catgtcccaa     62880
     gtgtccacca caccttgcac aacatatctc caccctcgca ggcattaaag aattgtcacg     62940
     atgatatgtg atggctccag gggatacctc ttcgtagaat gcgggccatc cacaacgagc     63000
     gtcgaacttg gccttgctcg aatacaacgg tctgtcgcag ttggcacaat ggtagacacc     63060
     ggactcgttg gtgtgtaaat acgcaccggt gttgggcctt tcagtggcct tatctctcag     63120
     caccatcagc tgcaatggtg tcagggcatc gttccacttc acgtcattcg attcgtcact     63180
     cattttcttg ctcttattcc agtactgcgt cagtacaatg tttcttctcc ctggaaaagt     63240
     cctgcgtaca gttataacgt acagcctgct ccacttattc attttttgat attgcttcct     63300
     ttctcccttt atttaaacta tcatcggcga catatttccc aataggcaaa gctgaaaaat     63360
     actatcgcta attataacaa agaagctagg tcgaaggact cgaaaagaca gaggtcgtac     63420
     tagcagagat agcaaatcag atggaggacg gtaaacaggc catcaatgag ggatcaaacg     63480
     atgcttcgcc ggatctggac gtgaatggca caatattgat gaataatgaa gacttttccc     63540
     agtggtcggt tgatgatgtg ataacttggt gtatatccac gctggaggtg gaagaaaccg     63600
     atccattatg tcagagactg cgagaaaatg atattgtagg agatcttttg ccggaattgt     63660
     gcttgcaaga ttgccaggac ttgtgtgacg gtgatttgaa taaggccata aaattcaaga     63720
     tactgatcaa taagatgaga gacagcaagt tggagtggaa ggacgacaag actcaagagg     63780
     acatgataac ggtactgaaa aacttgtaca ctactacatc tgcgaaattg caagaatttc     63840
     aatcgcagta cacaaggctg aggatggatg tcttggacgt aatgaagacc agctcaagct     63900
     cttctccgat taacacacat ggagtgtcca ctacggtacc ttcttcaaac aacacaatta     63960
     tacccagtag tgacggtgtg tctctttcac aaacagacta tttcgacaca gttcataacc     64020
     gacaatcacc gtcaaggaga gaatccccgg taacggtatt taggcaaccc agtctttccc     64080
     actcaaaatc tttgcacaag gatagcaaaa acaaagtacc ccaaatatct acaaaccaat     64140
     ctcacccatc tgccgtttca acagcgaaca caccggggcc atcacctaac gaggcgttaa     64200
     aacagttgcg tgcatctaaa gaagactcct gcgaacggat cttgaaaaac gcaatgaaaa     64260
     gacataactt agcagatcag gattggagac aatatgtctt ggtcatttgc tatggggatc     64320
     aagagaggct gttagaattg aacgaaaagc ctgtgatcat attcaagaac ttaaagcaac     64380
     agggtttgca ccccgccatt atgttaagaa gaagaggtga tttcgaagaa gtagcaatga     64440
     tgaacggaag tgacaatgtc acccccggtg gaagactcta atgtgcagtt gtcatgcaca     64500
     tcatcatact aaacttacac gaataggata acatgtatgc tagcagaata tatatgaaag     64560
     aaaaaaatta ttgatgcctt taaacttata ctattatact atattatgtt atattatatt     64620
     attagtttta tagatatatt gagatatgtt gaatatgatg acgaggatgg tggtttaagt     64680
     gtatggattg aattttctct tagctttcat taccttgatt ctttcttgat cttccttaaa     64740
     tttacttaac agttgattga tctcctgttt tttacgttct ctgacctgaa atctatagaa     64800
     atctttcttt gcctttttat ctatatttga aattggcttg gccttatttt catgtttgga     64860
     taatggattt ttgtttaata ttttctttct tatggaattc aatgacttgg tgttctttcc     64920
     tacaactaat gtgaatccat cctcatccac tatagaactt tgaacatcct cttgtgcttg     64980
     agcttcacgc tgttcaaaaa ttgccatatg tgtatgaata tcttctttca aataatcaat     65040
     atccagtggt ttgtagaagt taacaaaagt tgtgaatgat ggagtcgtat atgtccattc     65100
     aaatagttca tttggatgtt tggcatgcaa attcgagtat tttttcaaag cattccagca     65160
     gttatttata cttgcagcat caacaaattt taatagcgcc gtgtttcttg gtgtgtatct     65220
     cttctcgttg acgtcagtgg aggacatcag atcggaggtc aatgccgata aatctacttc     65280
     atgtaatcca aattcatcgt tatatagtag ttcctctaca tgcgatactg tatcgtattt     65340
     cccacagagc tgcccgacaa atttcttcat gtgctctatg ttagataata atggaaggtt     65400
     gaccaaaaac aaacagtcag actcgttgga atttgaactc tggtgtcttt tagcaaacat     65460
     gaaatgcaac gaagcttcct ggcttttggg tagtgccttg tgatccggta atttgaacgg     65520
     caccactata aacccgttct tcatggcgct aatgtcttca atacccatcc cgtaacactc     65580
     tatctgaggt tgttatctgt tacctagttc gttcgcccta aatgcctctt gctttaccat     65640
     cctctcaatg ttctcttctt tttcctgctt atttcttagg tgaccaaaaa gtgaaaaatt     65700
     ttccaattta acttacgtcg ttcgaagtga tgacaataag gatattcatt tattaatcgc     65760
     tatttgatac ccactcttgc tactacctct cttttaatcc aaaattacaa tttttacgtt     65820
     accattcatt acatagtgta tctctattca ttcaagactg tattttgttt gatatatata     65880
     tgtatatata catattattt tcgttagtgt tcggtttcca agttagaaat aatctactgg     65940
     aaatcctttg ggatcaaccc aagcttactc attctgattt tcacagcgtt tctgtgaccg     66000
     tctagaccct ccttcttggc aacgcacata acagctctac cgatgttttc taaaccttca     66060
     ggggtaatgt tttgggcagt gataaacttt tggaaggttg cagtgttggc accactgtac     66120
     tgcctagcgt aaccataggt tggtaatgta tggttagtac cacttgaata gtcaccgcac     66180
     gattctggag tgtaagcacc cacaaatacg gaccctgcat tgtcaaccaa tttaacataa     66240
     tcgttagcat tggcgatttg tagaatcaaa tgttctggtg catattggtt ggacatttca     66300
     agggcttctt cgtaaccgtc acaaagaacg atcgtactgt gagcaataca tttacgaaca     66360
     atatccacac gtggcagttg taaagcttga ttgtggacag catcttgaat ctcttgaatt     66420
     ttcttttcgc tcaagttaac accaacaagg ataacttggg agtcaatacc gtgttcagct     66480
     tgcgatagca aatcacttgc aacaaaatcc acatcggcat cttcatcggc aataaccaaa     66540
     acttcacttg ggccagctgg catatcaatg gaacatagag cttgagtgtc attttgaaca     66600
     tacattttgg cggcagtcac aaattgatta cctggaccca agatcttatc cactttagga     66660
     atagtttctg tcccgtaagc catagcagca acggcttggg caccaccagc tagaacaatc     66720
     ttggaagcgc caactttttc tgcgacataa acaacttcgg gtgaaacttt accatcagat     66780
     tttcttggtg gagatgcaaa cacaatctcc ttacattggg caacttgtgc tggaacacca     66840
     agcattaatg cagtacttgg taaaatggca gtgccaccag ggatatacaa accaactttt     66900
     tcaataggac gagggaatct ggaacacaag acaccaggtt gggtttcaac ttcaagagtc     66960
     tctgttggca attgagcagc atggaatttg cggacgtttt caattgaaag gtccaaagct     67020
     tccttcattt cctcggttaa accttcaaag tattcttctg ggaatggagc attaagaaca     67080
     ggattggata attttacacc atcaaacttt tctgtgtact ccaaaagggc agagttacct     67140
     ttgtctctaa cattttcgat gatcggattg actaaatgca taatttcaga agtcttttgg     67200
     attggtctgc tcaaagcctt ctgcacacca actttgtcgg aagccttcac cacgtccaag     67260
     tgaattggac cggtcagttt ttcttcttca gcctttggtt gtccaacaaa ctttggctta     67320
     gcatcacctt tccgtcttgt aaccttcaga tgcttcatat tcagattatt ctcgacgtcc     67380
     ttcaatgaaa catcgttggc cactaatttg gccagtgcaa agtagaacaa atcggcagcc     67440
     tcccaagaaa gctccttctt accctttgcc tcagtcagtt cttcagcttc ttccttgatc     67500
     ttggcatcta acaatgcaga gtcgttgaat agtcttctag tataagattc ctctggagcg     67560
     tcctgtagcc tttgttttag taaagattct agccccacca aaccatgctt gaattcacca     67620
     aagcaagaca tggtctccaa gtggcaaaat ccaacgtttt cttgttcaac gataaacttt     67680
     aaggcatccg aatcacagtc agtagagatt tgtaaaagct tttggccatt gccagaagtt     67740
     tcacccttga tccagatttc attcctagaa cgagaataat aaacgccacg acccaaatcg     67800
     atggcctttg ctatagattt cttcgaagaa tacaccaacc ctagacaacg ctcatattgg     67860
     tcgacaacta gggtggtata taaaccgtca ggacggtctg tacgtacttc accaagcact     67920
     tctttggtca acatatcctt gcttaatttc tttatggaca caattttatc ttgcgagaat     67980
     ttttgtttta ccatgaattg attggagaaa acaccgttct cttccacaac aacacgctcc     68040
     tttggtacat tcaattgttc aaccaagtgt tcggctgttt tagcatcttg gctagcaatg     68100
     aacagagaag aaactccgtt gttcaagaag gcaatgattt catcatcgct gaatttacca     68160
     cttggcaagg acaaagccac caatggaact tcttcctctt tggagaactg gagaatctct     68220
     tcattactca ggctcgagcc atccaaaagt acctgaccaa caagtgaaac gtattccttc     68280
     ttactattcc atgaggccag atcatcaatt aacggtagaa tcggcaaaac cattattcag     68340
     aaaaaaaatt ttgtaaacta ttgtattact attacacagc gcagttgtgc tatgatattt     68400
     ttatgtatgt acaacacaca tcggaggtga atataacgtt ccatatctat tatatacaca     68460
     gtatactact gttcatagtc atatcctttt cttaccttct atatcgaatg actgataaaa     68520
     aaacgtgagt cactgtgcat gggtttagca attaattaac taatttaccg gagtcactat     68580
     tagagtcagt tcgactgcct agaagaactg ctggttgtca ggattgtgat gggggcattc     68640
     tgctgtatta tgacccatcg tatcgcaatg ctcacaccac tgttgtcttc ctgccgtggt     68700
     atcgactggt gcaggggggt cgaaaattgg caacgattcc acggctgttt gtgcttgagc     68760
     ctgttccaac tgtttgattt tttcattagc ctcttcaagt tttttcgtta aggatgccac     68820
     ctcttccgat gaggaatctt gtggttttgt caaaaatagt tccttgctca aattttggta     68880
     ttctttactg agcgaatcgt tatgcatttt caattgttcg cgttctttag cccactttgt     68940
     cttgtgtaac tcaaattggt cttctatgtt gcgtaattgt tccagctgtt ttttcaggag     69000
     ttcgacatct tcgttggcac cagtgggttg attatgagaa agatttctct cttcgttttc     69060
     tttgatctct tcgtgtagtt ggcttacgac agcaagtagc tgttcattct cagcgtcaaa     69120
     aaactgcttt tgtttggctt gctgtctgcg ttcgagctcc aattgttgct tgagatggtc     69180
     tatctctttc tctctttctt gtattgtggc ttcataccta tcaaaagtcg gttgcacttc     69240
     ttcgaggacc attctttggt catcgagtag ccttttgtag tgtagttgtt tcctttgtag     69300
     cttttcgatg gtcaattggg cttctcgtaa ttcaattgta acttcgctgc tattgaggtc     69360
     attcatgtgg ccattgtccg gtttccaatc gctggtggtg ttgtgattag cctttctgtc     69420
     tgatgacagg atagagtcga cctccattct gtcttctctg ttatcgtaac caaattcttg     69480
     ctgttgatgg tgatccgatg cctcctggtc catcgactgt tgattaccgc tgtgccgact     69540
     ggtgatccgg aaacttctca tgggtgtggg ggatttagga tcatccatgg gagagaactg     69600
     gttagtgagc ctcacaatag atctgttttt gggtattgat agcggttcca ttgtcgttct     69660
     tctcgaggtt tgcgatatcg atgccttctc gatcaatgat gcgacttttt gcaactgaat     69720
     aaatagtcca ctttgaggat actccgtttg aaaatacttc ttccccatga atgatccatc     69780
     gttcttacca atgttggcaa gtaagtctac accagcaaac attccagctt tcgtgtccac     69840
     tggacccacg tatttcagtt gtccgcgccc caaatttggg atttgtatga aacatcctat     69900
     ctttctttga tatctatcca tggtatttca aacgcataca cagccagcca cagctcaacg     69960
     ccttttacct tgtcctttga tgcctgtctc gtccaaacgt ttttggtgtc ttggccaatt     70020
     gcccttctga aaaatctcac tgtccgcaac tcattaaaag atacccaagc aagctacacg     70080
     ataaagaaag gagaaagttc attaaaagaa cgtacatata gcgatacaaa cgtatagcaa     70140
     agatctgaaa tggatacgga taagttaatc tcagaggctg agtctcattt ttctcaagga     70200
     aaccatgcag aagctgttgc gaagttgaca tccgcagctc agtcgaaccc caatgacgag     70260
     caaatgtcaa ctattgaatc attaattcaa aaaatcgcag gatacgtcat ggacaaccgt     70320
     agtggtggta gtgacgcctc gcaagatcgt gctgctggtg gtggttcatc ttttatgaac     70380
     actttaatgg cagactctaa gggttcttcc caaacgcaac taggaaaact agctttgtta     70440
     gccacagtga tgacacactc atcaaataaa ggttcttcta acagagggtt tgacgtaggg     70500
     actgtcatgt caatgctaag tggttctggc ggcgggagcc aaagtatggg tgcttccggc     70560
     ctggctgcct tggcttctca attctttaag tcaggtaaca attcccaagg tcagggacaa     70620
     ggtcaaggtc aaggtcaagg tcaaggacaa ggtcaaggtc aaggttcttt tactgctttg     70680
     gcgtctttgg cttcatcttt catgaattcc aacaacaata atcagcaagg tcaaaatcaa     70740
     agctccggtg gttcctcctt tggagcactg gcttctatgg caagctcttt tatgcattcc     70800
     aataataatc agaactccaa caatagtcaa cagggctata accaatccta tcaaaacggt     70860
     aaccaaaata gtcaaggtta caataatcaa cagtaccaag gtggcaacgg tggttaccaa     70920
     caacaacagg gacaatctgg tggtgctttt tcctcattgg cctccatggc tcaatcttac     70980
     ttaggtggtg gacaaactca atccaaccaa cagcaataca atcaacaagg ccaaaacaac     71040
     cagcagcaat accagcaaca aggccaaaac tatcagcatc aacaacaggg tcagcagcag     71100
     caacaaggcc actccagttc attctcagct ttggcttcca tggcaagttc ctacctgggc     71160
     aataactcca attcaaattc gagttatggg ggccagcaac aggctaatga gtatggtaga     71220
     ccgcaacaga atggtcaaca gcaatccaat gagtacggaa gaccgcaata cggcggaaac     71280
     cagaactcca atggacagca cgaatccttc aatttttctg gcaacttttc tcaacagaac     71340
     aataacggca accagaaccg ctactgaacg atgattcagt tcgccttcta tcctttgttt     71400
     acgtatttgt ttatatatat aactttattt ttttttatta attgggctgc aagacaattt     71460
     tgttgtcagt gatgcctcaa tccttctttt gcttccatat ttaccatgtg gaccctttca     71520
     aaacagagtt gtatctctgc aggatgccct ttttgacgta ttgaatggca taattgcact     71580
     gtcacttttc gcgctgtctc attttggtgc gatgatgaaa caaacatgaa acgtctgtaa     71640
     tttgaaacaa ataacgtaat tctcgggatt ggttttattt aaatgacaat gtaagagtgg     71700
     ctttgtaagg tatgtgttgc tcttaaaata tttggatacg acatccttta tcttttttcc     71760
     tttaagagca ggatataagc catcaagttt ctgaaaatca aaatggtagc aacaataatg     71820
     cagacgacaa caactgtgct gacgacagtc gccgcaatgt ctactacctt agcatcaaat     71880
     tacatatctt cgcaagctag ttcctcgacg agtgtaacaa cagtaacgac aatagcgaca     71940
     tcaatacgct ctacaccgtc taatctactc ttttctaatg tggcggctca gccaaaatca     72000
     tcttcagcaa gcacaattgg gctttcaatc ggacttccca tcggaatatt ctgtttcgga     72060
     ttacttatcc ttttgtgtta tttctacctt aaaaggaatt cggtgtccat ttcaaatcca     72120
     cccatgtcag ctacgattcc aagggaagag gaatattgtc gccgcactaa ttggttctca     72180
     cggttatttt ggcagagtaa gtgtgaggat cagaattcat attctaatcg tgatattgag     72240
     aagtataacg acacccagtg gacctcgggt gataacatgt cttcaaaaat acagtacaaa     72300
     atttccaaac ccataatacc gcagcatata ctgacaccta agaaaacggt gaagaaccca     72360
     tatgcttggt ctggtaaaaa catttcgtta gaccccaaag tgaacgaaat ggaggaagag     72420
     aaagttgtgg atgcattcct gtatactaaa ccaccgaata ttgtccatat tgaatccagc     72480
     atgccctcgt ataatgattt accttctcaa aaaacggtgt cctcaaagaa aactgcgtta     72540
     aaaacgagtg agaaatggag ttacgaatct ccactatctc gatggttctt gaggggttct     72600
     acatacttta aggattatgg cttatcaaag acctctttaa agaccccaac tggggctcca     72660
     caactgaagc aaatgaaaat gctctcccgg ataagtaagg gttacttcaa tgagtcagat     72720
     ataatgcctg acgaacgatc gcccatcttg gagtataata acacgcctct ggatgcaaat     72780
     gacagtgtga ataacttggg taataccacg ccagattcac aaatcacatc ttatcgcaac     72840
     aataacatcg atctaatcac ggcaagaccc cattcagtga tatacggtac tactgcacaa     72900
     caaactttgg aaaccaactt caatgatcat catgactgca ataaaagcac tgagaaacac     72960
     gagttgataa tacccacccc atcaaaacca ctaaagaaaa ggaaaaaaag aagacaaagt     73020
     aaaatgtatc agcatttaca acatttgtca cgttctaaac cattgccgct tactccaaac     73080
     tccaaatata atggggaggc tagcgtccaa ttagggaaga catatacagt tattcaggat     73140
     tacgagccta gattgacaga cgaaataaga atctcgctgg gtgaaaaagt taaaattctg     73200
     gccactcata ccgatggatg gtgtctggta gaaaagtgta atacacaaaa gggttctatt     73260
     cacgtcagtg ttgacgataa aagatacctc aatgaagata gaggcattgt gcctggtgac     73320
     tgtctccaag aatacgactg atgaaaataa tattgacgtt cgcatttaat ctatacctat     73380
     aattctgtac ttatatactg ttccttaatt gaagatttca acatcgtttt tgatgtaggt     73440
     cttttcacct ggaggtgcgg ctggggtacc gaagactaat tgagcttgta cggtccaaga     73500
     ctcagggatt ttgcttggca aagcagcttt tatgtaacca ttgtagtgtt gtaggtgacc     73560
     acccaggccc attgcctcca aggcaaccca cgagttgatt tgagcggcac cagaggtatg     73620
     gtccgcgaaa ctagggaatg cagctgcgta cgctgggaag tcagccttta gcttttcagt     73680
     taccttgtcg tcggtgaaga agattacaga accaaaggcc tcatcccttg ctgaagcagg     73740
     cctcttttga ccggcagggc tttctatagc cttagtcact tcgtcccaaa cttttttgtg     73800
     agtttcacca gtcaagataa cagcgcgatt tggctgggag ttgaaagcgg tgggtgtttc     73860
     tttaatgatg gtttggacga cggattggat gtcgttgata gtaatttcac caggtaactc     73920
     cggtttcaaa gcgtaaatag tacgacgagc agttaaagtt ttcaaataag ttgcaacagc     73980
     agacatgata ttggattgtt tttttgtata tatgttgata taggatactt cagtctacga     74040
     aaaaagtaca aattatgtag tcagttcctt cagtatggtg tccttatata ctgtagtttg     74100
     gacaaggtgc aaatgccaag accctagccc gaaaagctcg aggcacccca ggatcttttt     74160
     ctttacgtaa ttttcacgta aaacgccaca gtccgatttt tctcgaataa tcattagtaa     74220
     aagcggtata ctggattatt gtacgataac aaggtagagc tttattacta agctaagacg     74280
     ttcttacatc aatagtgctg ttcgttattg atgttaggag aaggagcggg tctggtgaat     74340
     agtgtaagca gtgtttctga actttttctt cgtctaagtc cttgtaatgt aaggtaagaa     74400
     tgcaagcatc ttgtttgtaa cgcgattgta cgttgacgtt agtaagtcac aaacccaagc     74460
     ttaacttctt cgtgaggaag gaaagtgttg tctcctactt ttttcaaatt ttcgaattgt     74520
     atttatattt atttagtact tcttgagttt acatatcctt cgtaaaaatg caacttttgt     74580
     cgaaaaacac ttccaaaaaa aaataataat gaatttatga agcatactaa cgagcgagca     74640
     catcgctgag gtatcattac ttcatgagat aaattaagat ctcctcatat gcgaatttcc     74700
     tgttcagtga taaacgttga ttacgttatt gataaaagtc ttttcttctg gcaaggcagt     74760
     tggaacacca aagaccaatt gagattgtac agtccacgca ataggaacat cttgaggcaa     74820
     agcagatttg acgtagtcat tatagtgttg caaattagcc cccaatccca atagttcgag     74880
     ggcagtccaa gactgaattt gcacagcacc ggtcgtatga gcggcgcatg ttgggaaagc     74940
     ggctgccaag gctggaaaat ctctttgcag tttttcagtt ggtccttcat cagtgaagaa     75000
     aatgactgaa ccgtaagcct catctctgca agactctggt ctcttcttgg cttcagcagt     75060
     tggcattgcg ctcgcaacag catcccatat ccttttgtgt gtatcaccaa cgataatgac     75120
     agcgcgattc acttgtgagt taaaagctgt tggcgtattc ttgagaataa cgtgtacagt     75180
     tctctttaca tcatccaaac cgacaccttg tggtaattcg ggcttcaaat tgtagatggt     75240
     acgacggttt gtaatagcgt ttaagtagtt tccagttggg gacatttctt tggcttggag     75300
     gtctggtgtt cttgattttg atggtgtata tagctttaaa aaaccaaaaa tgatcaacct     75360
     ttatatctct cttcgatcac aacatgggtg gagacaaaca caaagtagtg atgacccact     75420
     caggtgttaa agtgtgtcat atctgcaaat gacactgtat ttttttttcc tttgccattt     75480
     attgtcgcag taaggaaaag cgcagagcaa agctgacaaa ttgaaaaatt attcggaaga     75540
     gcattgacaa atattgatta ataatcaagt aacactcgca gacattgtta tttcagaagt     75600
     aaaaatatcg cagaacaagt tggttaaact gaatgcttca gtcattctaa tgctaattac     75660
     accttaacaa aattaaaaat tcttaacgta gatttttaaa aaaggcaaga agatcgttcc     75720
     tgatgcacga cgaaaacggt tgcaccccta ctaaggcaaa attgcatatg cggatgaaat     75780
     caaacctctt ctgttgcatt aagaacaaaa ggaaatcatt tttctctcac ttcatattat     75840
     ttcacttata ttttcctctc cacttccatc acgcaatcgt tagtgctttt tatttttttt     75900
     cttcgctcat aaaggactag aattaaaatg aaaatcgtct atcattacac gtatgctatt     75960
     actacaaaac agaagtacaa aaatgaataa atataaaaga agtaaatgct ttttttttta     76020
     acaccagaag gcaacgaccc ttttccaata aggtccgttc ctcaaacgtt ccctatattc     76080
     ttcgtcttct tgcttgatta attcttcatc aaagatttgt ctatgagaat ctaggtcgat     76140
     cttgtctgcc ctgatgaaca gtttccaatc cttgtgccag accttgtagc cgacataaag     76200
     tgcaatcaag attggcatag ccaagtagtt ttcgaaaaag gcttgtgcat ccagcttacc     76260
     ttcaccaatg ggggcgatag cgacccaaaa ttgggcaata agaattaaaa tcatcataat     76320
     gcaagcgtag gcagatcccc aaacaccagt ttgagatttg aaacccaatt ctccaagaga     76380
     tctcccttgg actttcatgg ctcttctaaa tctaagatgg gataaacaaa tggcagtcca     76440
     tgtgaaaagc tgagacaaac cagaaatggc caataaccaa gtgaaaactt gttcttcctt     76500
     gggagatgca gcacagaagg caataacggc aaacaatgca gaaacaccca tggcaatcaa     76560
     tggtctaccg gctctgtcga tgtaggagaa aaccttagga gcgtaacctt gctcggatag     76620
     agttaaaaat aaacgagcac tggagtagaa ggaggagtta gccatggaca gcacggaaag     76680
     tagaataacg gcgttaatga agtgtgggac gacacggaca ccgtgggatg caacagcaat     76740
     gacatatggc gaggctttag taccaccacc ggtagaaccc aataattgat cggaattgta     76800
     tggcaccaag aaacccagta gaataatggt agccaagaat aggaataaga ttctgtagat     76860
     catttgtttg gccgcacctg gaatggcctt tcttggatta gattgttctg cagtggtgat     76920
     ggcaataaac tctgaaccac caaaggcaaa agcagcagtc actaatgttg cagcaacacc     76980
     tttaaatctg tcaatggcat gtttaccatt gaaagcgccc ggatcgtgcc agtatttacc     77040
     accaataaaa ccatcattac cagcgccacc aacatcgatg ataataccaa gaatgaagaa     77100
     cccagtcatc atcaaaattt tgcaacagtt gaagaagaac tcagcttctg cataaccacg     77160
     agcaccgaaa atattaatag taatcaccaa aacatagaaa ataatgacga acacatccgg     77220
     gttcacagat gtcgtccaat atttgatagt catggatgcg gtcaccaatt ccagaggaca     77280
     cacacacagc cattgcaaac aataaaccca agcgactgca aacccaaaac catcatccac     77340
     aaggaaactg gggtatgcat tgtagccacc agtcaagtta ctatacacta gcgccatttc     77400
     accacatgct tgaataatac agtacaagat agaacccata atagcgtaac caataagtag     77460
     tccagctgga cccgcatgaa ccaacgcggt accgttaccg accaataacc cagtaccgat     77520
     acccgtaccc aacgcaatca tcagaacatg tctaggctga atggttttct tcagcgagtc     77580
     cgacttatga cctgtattag cgcctatgtt gtccgaactt tcattttttt ctagttcttg     77640
     agcctgtcta gaagaaggtg agatagccga cgtaagatcg ttcatttgtg ttgcttctac     77700
     ttcatcctgt ggaccctgat ccgctctttt aaaggagtcg aaaaacctac gcacggcaga     77760
     agtgttatgc tgttcgtaac ctaaatgagg ttgtgaggat ggacggtcat tggagcctgt     77820
     ttcgaaatat tcaatttcat tatcctgccc cgtggcatgt atttctgtgg agctattttt     77880
     caagtctttc agttcgtata gagacttcga cgacgacatt gtgcgaagct atctttgtct     77940
     atattagcgt gcttcttcta taaagattac ataataaact tgttctacat tgttgtgggc     78000
     agaccatcaa agacaaagca cttatatatg tatgtaaaac aaatgagtat tacgaggaaa     78060
     ataacaaaaa gaaactaatc acgaaggata tgagtcttgt tagcggacga ggggaagata     78120
     gcgcaagaca cacgtatagc cgacctatcc tatgcatctt agccgtctta tcaggattga     78180
     tttgcggttc agtgaaagag ataaccactg ccaagctgga agaaatggct agaaggcact     78240
     aaaaaaagag cctcgcagcg caacttaaga actgtggact actaaggagc agcaatccgc     78300
     tggacgtggg ggagttgaaa gttggccgga tactgcaacc tgcttatcta tgactcgatg     78360
     agaccgttat ttagtgcgat ggtgccactg ggagtgccat caacggcaaa gttgcagctt     78420
     tttgcagcag atcagtgccg cttagacggc accctcaagc ggcactgaag aacggcgcgc     78480
     tttttttttt cttctattat gccggtcaag gaaaaaaaga aaccaaaaaa aaatgccgtg     78540
     ggaggcacgg atgcaagatt tctccaaagt ccctttttag ccgccgagga aatgaggaaa     78600
     taaggggtta gccgccgagt gaagccgccg aggtataaaa gggagaatgc acaccttcgt     78660
     aagaagattc tatttgaaag agtgctaggt aaagtcatca aaaggcttat tgatataata     78720
     attgctttgc aaaatggaaa acaaatgact ttgaaaatgg gagaaaacaa aaattatata     78780
     ggtaatgttg agttcttgat tttttttttg tttctgtcct tgccacagct cttttcatgg     78840
     aacattgggc tctaggataa tttttttatg ttttctgtta tgtttgccat ggtaggttga     78900
     ggtaaaggcg ctctttcagc aatgacgatt tatgctaata tgttttcctt aaaaggaaaa     78960
     catctcgttc tttttttcgc gtgctgtgca agaaaacgcg taacgcagtc ttagtaaaag     79020
     ggctctcttg aaaactacat gaaaactaaa aaagaagatg taaatttgga tacaacagcg     79080
     tagaatagca taatagagtg tgcaataaac gtgtataggc ttgataatag tgctgacgta     79140
     aattaccaga actactgcag tatgactgtg gcgaataccg agacccattc tgctgctaaa     79200
     ccatcgagta ctataggccc atggaagctt ggtgaaacac tgggctttgg tagcaccggc     79260
     aaggtccaac ttgcgcaaca tgagcgcacg ggccatagaa cagccgtcaa agtaatctca     79320
     aagtccattt tcaacaacaa cggaaaccac agtaacgacg attcagtgct gccatacaac     79380
     atcgagcgtg agattgttat tatgaaactt ttgagccacc caaacgttct gagtctttac     79440
     gacgtttggg aaaccaacaa taacctgtac cttatcctgg aatacgccga aaagggagaa     79500
     ctgttcaact tgcttgtgga ccacggtccc ttgcccgagc gtgaggccat caattgcttc     79560
     agacagataa ttataggcat ttcatactgc catgcgctag gaatagtaca tcgggattta     79620
     aagccagaaa atcttttgct cgatagtttc tataatatca aaattgcgga ttttggtatg     79680
     gcagctttac agacagacgc cgacctgcta gaaacttctt gtgggtctcc tcattatgcc     79740
     gctcctgaga tcgtatcagg tctgccctat gaaggatttg ccagcgacgt ttggtcttgc     79800
     ggtgtaatcc tctttgccct tttaacgggt agactaccct tcgatgaaga aaacggtaat     79860
     gttagggatt tgttattgaa agtccaaaag ggccagtttg aaatgcccaa tgacaccgaa     79920
     atttccagag atgcacaaga tttaatcggc aagattctcg ttgtagatcc caggcaaaga     79980
     ataaaaatca gagacatcct tagtcatcca ctgctaaaaa aatatcaaac cattaaggat     80040
     tccaaaagta tcaaagattt acctcgtgaa aatacctatc tatatccact ggctgactcg     80100
     aacaaccata ctagcgcctc tatcgatgat tcaatcctac aaaacttggt ggtactttgg     80160
     catggtagac acgccgatga catcgtatct aaactgaaag agaatggaac caacaaagaa     80220
     aaaattctat atgcgctact ataccgtttc aaactggact ctgtaagggg atcgaataag     80280
     aagaaccgca ataagataaa gaaaaccaaa aaaaataaaa gatctagcac actttcgtca     80340
     tcgtcatcat tattattgaa caaccgaagc atacaatcta cgccacgcag acgtacatcc     80400
     aagaggcatt ccagggaatt ctcttctagc aggaagagat cgtccttttt actgtcctcg     80460
     aatcctaccg atagttctcc aatacctttg agaagtagta aaagaattac acatattaac     80520
     gtagcgtctg caaataccca agcaacgcca agtggtgtcc cgaatcctca caagaggaac     80580
     tcaaaaaaac ggtcaagcaa aagattatct tatatgccta atacaaaaag aagctcacta     80640
     acatcaaaat cattatcaaa ctttactaac ctaatagatg atgatgattg ggagtacatt     80700
     gaaaaggatg caaagagaac aagttccaac ttcgctacac tgattgatga aatatttgag     80760
     cctgagaaat ttgaattggc gaaaagagaa aaggctgaac ttcaaagaaa agttcaggaa     80820
     gcaaaaaggc aatcagtgaa tgcacagaag attaatgagg acgagtttgg atccgaagtt     80880
     tctgatggaa tgaaagagct gaaaaaaata aatgacaaag tgtcgtcccc gttgataaat     80940
     tacgaatttt cgcaacaaga actattgcaa gatatagaca ccttactaac gaatcgttat     81000
     caactttcgt catatactag gcctatttcg agactggatc ccggattaac gcctgttact     81060
     gagacacttc ctaacaacct aaaagaaaaa acagctctgc tgcaggatac tgaaaagaaa     81120
     ataatagaaa cgatacgcag atccaaattt ttaggatcgc tactaaatgt tagaggggga     81180
     ctatcgccag ggaaaagtga actggcacct atcgaagagt ctcccatagt ttcaaccaca     81240
     ccactaatat ataatgatcg aatggaacct cgtaggatat ccgatgtgga agtcccacat     81300
     ttcacgagga aatcaaaaca ctttactact gctaataatc ggcgctcagt cttatctttg     81360
     tatgcgaagg attcaatcaa agacttaaac gaatttttaa taaaggaaga tcctgatttg     81420
     cctccacaag gaagcactga taacgaaagt aggagcgaag atcccgaaat agccgagagt     81480
     atcactgatt caaggaatat acaatatgat gaggatgata gtaaggatgg tgataatgtg     81540
     aataatgata atatattgag cgactttcct caaggcgttg gcatatcaca ggaatacgac     81600
     atgaaggata aaaatccaaa ccaatctcca atatcaaaaa gcgcagagcc cacactggta     81660
     gtgaaacttc cgtctttgag ttctttccaa ggaaaaaacg ccagtgggtt gggcctatac     81720
     caaagagagc cttctaaggt aaccttaccg agccttacaa gtaataacag cagcgtcgga     81780
     gaaaacatag aggatggggc ggaaaaaggg actgagagtg agaaaatcgc tgcttccctg     81840
     tcagacgatg acttgaagga agataatgac aagaaagata acgacacagt gaatgcccct     81900
     actacagtaa aaaagccacc taacagcgta ctcttgaaaa aattctcaaa aggtaaaatc     81960
     ttagaacttg aaatacatgc caaaatacct gaaaagagac tatacgaggg cctacataaa     82020
     ctactagaag gctggaagca atacgggttg aaaaacctgg tgtttaacat cactaatatg     82080
     atcataacag gaaaattggt gaatgacagt attttatttt tacgatctac gctttttgaa     82140
     ataatggttt taccaaatgg agacggtaga agtttaatta aattcaataa gaaaacagga     82200
     tctactaaaa cgctgaccaa gcttgctaca gaaatccaaa ttattttaca aaaagaaggt     82260
     gttttggaca aataaaaaaa agggagggat aatcgatccc caaatggaca atacgatgta     82320
     acaccgttat ataattaata aatgtatata tgtaactatt ttttgaaaaa aataaaatgg     82380
     taatttatta aatatttgga ccggtcaaca atctcagata tagttgaaaa aatctttaat     82440
     tgtaatagca gaaaaaaaaa actccgatac ggggagtcga accccggtct ccacggtgaa     82500
     agcgtgatgt gatagccgtt acactatatc ggataacaaa ttattaaaat tatttaataa     82560
     aaagatgaac taatggtgta taaaaacatc ataaaaactc aactcaactg ttccaataaa     82620
     atctgcaatt taaattaatt attctgaaaa aacacgtaaa ttgttggaat ggaaccctaa     82680
     aatatttcct ctttagtact gttggaatag aaatcaacta tcatctacta actagtattt     82740
     acattactag tatattatca tatacggtgt tagaagatga cgcaaatgat gagaaatagt     82800
     catctaaatt agtggaagct gaaacgcaag gattgataat gtaataggat caatgaatat     82860
     aaacatataa aacggaatga ggaataatcg taatattagt atgtagaaat atagattcca     82920
     ttttgaggat tcctatatcc tcgaggagaa cttctagtat attctgtata cctaatatta     82980
     tagcctttat caacaatgga atcccaacaa ttatctcaac attcacccat ttctcaagta     83040
     ctattcatgt tacttgagaa atgggtgaat tttgagatag ttgttgggat tccattgttg     83100
     ataaaggcta ataatattag gtatacagaa tatgctagag gttctcctcg agcatatagg     83160
     aatcctcaaa atggaattag catttctaca taataacctc aattcccttt tgtggattca     83220
     catattctcg atcggaactc ctagcatagt gcagacaaca ctcacatagc tctcccattt     83280
     atcaagttgg aattcactcc aagaaatttt cttgcttctc tctttcccac agaaatgaaa     83340
     aggaacagtt tggcggctat tgttttagcc cttacttttt ggaccctttg aaaaaatgcc     83400
     aagaatgcgt gacggtttcc ctccatgctc gagaaccaca aaaaccctat gtggtattcg     83460
     attatgcgac tcacggcaaa tatttgactt gtcaaagtta ttcgggattt ccttgaatcc     83520
     ctgagaagtg aaatggaaag aatttaaggg cataaatacc tttcaagcac ccagaagaac     83580
     agtaaaataa agcaaggtac gtgaaattaa tatttttaaa tggttctaac cgatgccgaa     83640
     gaactgcgca gtccggttat aacgtctgac atgtcctttt ttgatttgga atccaaccac     83700
     tcaagtgact ctgttcattt actttgcgaa aaatataccc acaaattgcc catcgaaagt     83760
     gaatcgcaaa ccaccttcag actggcaccg acaaagcaaa gattatacag acagagtact     83820
     ttatacgtac cgttaagtct caagcaaagg gttttcttat ttactgaacg ggtaaagagt     83880
     atctgggccg gcttgccaag atgcaaaccg aataagtatt tcaaagttgc atttgcctta     83940
     gccgtcctga caccattggc tatttggata ttttatattg actttcgtgt acattgatca     84000
     catcgactgt tctattggca aatgaaccac gggcattgac tatttttcag gttactacta     84060
     tatattattg ttggaataaa aatcaactat catctactaa ctagtattta cgttactagt     84120
     atattatcat atacggtgtt agaagatgac gcaaatgatg agaaatagtc atctaaatta     84180
     gtggaagctg aaacacaagg attgataatg taataggatc aatgaatatt aacatataaa     84240
     atgatgataa taatatttat agaattgtgt agaattgcag attccctttt atggtgttgg     84300
     aataaaaatc aactatcatc tactaactag tatttacgtt actagtatat tatcatatac     84360
     ggtgttagaa gatgacgcaa atgatgagaa atagtcatct aaattagtgg aagctgaaac     84420
     gcaaggattg ataatgtaat aggatcaatg aatattaaca tataaaatga tgataataat     84480
     atttatagaa ttgtatagaa ttgcagattc ccttttatgg attcctaaat cctcgaggag     84540
     aacttctagt atatctacat acctaatatt attgccttat aaaaaatgga atcccaacaa     84600
     ttacatcaaa atccacgttc ttttcatatg gattcctaaa tcctcgagga gaatttataa     84660
     tatagtctgt atacataata ttatagcttc taacgacaat ggaattctaa caattatcaa     84720
     attgtccgcc agttcctcaa aaagatccat gtataatctt cattattaca gccctcttga     84780
     cctctaatca tgaatgttct caaataaatc tgttggaata aaaatcaact atcatctact     84840
     aactagtatt tacgttacta gtatattatc atatacggtg ttagaagatg acgcaaatga     84900
     tgagaaatag tcatctaaat tagtggaagc tgaaacgcaa ggattgataa tgtaatagga     84960
     tcaatgaata ttaacatata aaatgatgat aataatattt atagaattgt gtagaattgc     85020
     agattccctt ttatggattc ctaaatcctc gaggagaact tctagtatat ctacatacct     85080
     aatattattg ccttataaaa aatggaatcc caacaattac atcaaaatcc acgttctctt     85140
     catggtagcg cctatgcttc ggttacttct aaggaagtcc catcaaatca agatccgtta     85200
     gccgtttcag cttccaattt accggaattt gatagagatt ccactaaggt taattctcaa     85260
     caagagacaa cacctgggac atcagctgtt ccagagaacc atcatcatgt ctctcctcaa     85320
     cctgcttcag taccacctcc acagaatgga cagtaccaac agcacggcat gatgacccca     85380
     aacaaagcta tggcctctaa ctgggcacat taccaacaac cgtctatgat gacgtgttca     85440
     cattatcaaa cgtcacctgc gtattatcaa ccggacccac actatccgtt gccacagtat     85500
     atcccaccac tgagtacttc ctcacctgat ccaatcgatt cacagaatca acactctgaa     85560
     gtacctcaag ctgagacaaa ggtgagaaat aacgtcttac caccacacac tttaacatca     85620
     gaagaaaact tttctacatg ggttaaattt tacatcagat ttttgaagaa ctctaatctc     85680
     ggtgacatca ttccaaatga ccagggtgaa atcaaaagac aaatgactta tgaagaacat     85740
     gcgtatatat acaatacctt ccaagcattt gccccatttc atttattgcc aacatgggta     85800
     aaacaaattt tagaaattaa ttatgctgac atccttacag tcctttgtaa aagtgtgtcc     85860
     aaaatgcaaa ctaacaatca agaattaaag gattggatag ctcttgccaa ccttgagtac     85920
     gacggaagta catctgctga tacatttgaa attacagtca gtacgatcat tcagaggcta     85980
     aaagaaaaca atatcaatgt tagcgacaga ttggcctgtc aactaatact taaaggtcta     86040
     tccggtgact tcaaatacct acgtaatcaa tatcgtacca aaacgaacat gaaactttcc     86100
     caattattcg ctgaaattca gttaatatat gacgaaaata aaatcatgaa tctaaataaa     86160
     ccgtcccaat acaaacaaca cagcgaatac aaaaatgttt ctcgcacatc tccaaacacg     86220
     actaacacaa aggttacaac tcgtaattat cagagaacaa atagttcaaa accaagagca     86280
     gcaaaagctc acaatattgc tacatctagt aaattctcaa gggtgaacaa tgatcacatt     86340
     aatgaatcaa ccgtttcatc acaatactta agcgatgaca acgaacttag tcttaggcca     86400
     gcaacagaaa gaatctaagc caacacacac aatagactcg aatgacgaac tacctgatca     86460
     ccttcttatt gattcaggag cttcgcaaac gcttgtcaga tcagcccatt atttacacca     86520
     tgcaacaccc aattctgaaa taaacatagt cgatgctcaa aaacaagaca ttcctataaa     86580
     tgccattggt aatcttcact tcaactttca gaacggcacc aaaacatcaa taaaagcact     86640
     acacacacca aacatagcct atgatctatt aagtttgagt gagctggcta atcaaaatat     86700
     tactgcctgc tttaccagaa acactttaga aagatcggat ggtacagtcc tagctcccat     86760
     agtcaaacat ggagactttt actggttatc taaaaaatac ctaattcctt cgcacatttc     86820
     aaagctaaca ataaacaacg tcaacaaaag caaaagcgta aataaatatc catatccgtt     86880
     aatacatcga atgcttggac atgctaactt ccgaagtatt cagaagtctc ttaagaagaa     86940
     tgcagttaca tatttgaagg aatcggatat tgaatggtct aacgctagca catatcaatg     87000
     tcctgactgt ctaatcggca aaagcacgaa acatagacat gtcaaaggat cacgactaaa     87060
     gtaccaagaa tcatatgagc cttttcagta cttgcatacc gatatatttg gtcctgtaca     87120
     tcacttaccg aaaagtgcac cttcttactt tatatcgttt acagatgaga aaaccagatt     87180
     ccaatgggtg tacccattac acgaccgtcg tgaagaatct atcctcaatg tttttacatc     87240
     gatattagca tttattaaga accaattcaa tgctcgcgtt ctagttatcc agatggatcg     87300
     tggctccgag tacactaaca aaactcttca taagttcttt acgaacagag gtattactgc     87360
     atgctataca accacggcag attctagagc acacggtgtc gctgaacgat taaatcgtac     87420
     tttattaaac gattgtcgca cactgcttca ttgcagtggt ctaccaaatc atctatggtt     87480
     ctcagcagtc gaattttcta ctataatcag aaattcatta gtctcaccaa aaaacgataa     87540
     atccgcaaga caacatgcag gtttagctgg actggacatt actactatac tacctttcgg     87600
     tcaaccggtt atagttaaca accataatcc cgactcgaaa atacatcctc gtggcattcc     87660
     aggttacgcc ttacatccgt cacgaaactc ttatggctat attatctatc ttccatcatt     87720
     aaaaaagaca gtagatacta ccaattacgt tatattacaa gacaagcaat ccaaattgga     87780
     ccaattcaat tatgatacac tcacctttga tgatgatctc aatcgtttaa cagcccataa     87840
     ccaatctttt attgaacaaa atgaaacgga gcagtcatat gatcaaaata cagaatctga     87900
     tcatgactat caatcggaga ttgaaataaa ctctgatcct ctagtgaacg acttctcgtc     87960
     ccaatcaata aaccctttac aattagacaa ggaaccagtc caaaaagtac gtgcaccaaa     88020
     agaagttgat gccgacatat ctgaatacaa tattcttcca tctcctgtac gatctcgtac     88080
     accccatatc attaataaag agagtaccga aatgggtggt accgttgaat cagatactac     88140
     ttcacctaga cactcgtcta ccttcactgc acgaaaccaa aagcgacctg gtagtcccaa     88200
     tgatatgatt gatttgacct cacaggatag agttaattat ggacttgaaa acatcaaaac     88260
     tacacgtttg ggtggtacgg aggaaccata tattcaacga aatagtgata caaatatcaa     88320
     atacaggact acaaatagta cgccctcaat agatgaccgt tcgtccaaca gtgaatccac     88380
     tactcccatc atctccatag aaacaaaggc tgtatgtgat aatacaccct ccattgatac     88440
     ggatccgcca gaatatcgat cttctgacca tgcgactcct aatataatgc ctgacaaatc     88500
     ctcaaaaaat gttacggctg attctattct tgacgacctc ccacttcctg acttaaccca     88560
     tcaatctcct acggacactt ctgatgtttc aaaagatatt ccacacatac actctcgtca     88620
     gactaattcc agtttgggtg gtatggatga ttctaatgtt ctgactacta ccaaaagtaa     88680
     gaaaagatca ttagaagata atgaaactga aattgaggta tcccgagaca catggaataa     88740
     taagaatatg agaagtctgg aaccaccaag atcgaagaaa cgcataaatt taattgcagc     88800
     aataaaagga gtgaaatcga tcaaaccagt tcgaacgacc ttaagatatg atgaagcaat     88860
     tacttataat aaagacaaca aagaaaaaga cagatatgtt gaagcttatc ataaagaaat     88920
     tagccaacta ttgaaaatga acacttggga tacaaacaaa tattatgata gaaatgacat     88980
     agatcctaaa aaagtaataa actcaatgtt tatatttaac aagaaacgtg atggtacaca     89040
     caaagctaga tttgttgcaa gaggcgacat tcaacacccc gatacatatg attctgatat     89100
     gcaatccaat accgtacatc actatgcact gatgacgtca ctgtcaatcg cattagacaa     89160
     cgactattat atcacacagc tggacatatc ctctgcttac ttatatgctg atatcaaaga     89220
     agaattatac ataagacctc caccacattt aggtttgaat gataaattac tacgtttgag     89280
     aaaatcactc tatggtttga aacaaagtgg tgcaaactgg tatgaaacca ttaaatcata     89340
     tttaataaat tgttgcgaca tgcaagaagt tcgcggatgg tcatgcgtat ttaagaatag     89400
     tcaagtaaca atttgcttat tcgttgatga tatgatatta ttcagcaaag acttaaatgc     89460
     aaataagaaa atcataacaa cactcaagaa acaatacgat acaaagataa taaatctggg     89520
     tgaaagtgat aacgaaattc agtacgacat acttggatta gagatcaaat atcaaagaag     89580
     caagtacatg aaattaggta tggaaaaatc cttgacagaa aaattaccca aactaaacgt     89640
     acctttgaac ccaaaaggaa agaaacttag agctccaggt caaccaggtc attatataga     89700
     ccaggatgaa ctagaaatag atgaagatga atacaaagag aaagtacatg aaatgcaaaa     89760
     gttgattggt ctagcttcat atgttggata taaatttaga tttgacttac tatactacat     89820
     caacacactt gctcaacata tactattccc ctctaggcaa gttttagaca tgacatatga     89880
     gttaatacaa ttcatgtggg acactagaga taaacaatta atatggcaca aaaacaaacc     89940
     taccaagcca gataataaac tagtcgcaat aagcgatgct tcatatggta accaaccata     90000
     ttacaagtca caaattggta acattttcct actcaacgga aaagtgattg gaggaaagtc     90060
     gacaaaggct tcgttaacat gcacttcaac tacagaagca gaaatacacg cagtcagtga     90120
     agctattccg ctattgaata acctcagtca ccttgtgcaa gaacttaaca agaaaccaat     90180
     tattaaaggc ttacttactg atagtagatc aacgatcagt ataattaagt ctacaaatga     90240
     agagaaattt agaaacagat tttttggcac aaaggcaatg agacttagag atgaagtatc     90300
     aggtaataat ttatacgtat actacatcga gaccaagaag aacattgctg atgtgatgac     90360
     aaaacctctt ccgataaaaa catttaaact attaactaac aaatggattc attagatcta     90420
     ttacattatg ggtggtatgt tggaataaaa atcaactatc atctactaac tagtatttac     90480
     gttactagta tattatcata tacggtgtta gaagatgacg caaatgatga gaaatagtca     90540
     tctaaattag tggaagctga aacgcaagga ttgataatgt aataggatca atgaatatta     90600
     acatataaaa tgatgataat aatatttata gaattgtgta gaattgcaga ttccctttta     90660
     tggattccta aatcctcgag gagaacttct agtatatcta catacctaat attattgcct     90720
     tattaaaaat ggaatcccaa caattacatc aaaatccaca ttctcttcaa aatcaattgt     90780
     cctgtacttc cttgttcatg tgtgttcaaa aacgttatat ttataggata attatactct     90840
     atttctcaac aagtaattgg ttgtttggcc gagcggtcta aggcgcctga ttcaagaaat     90900
     atcttgaccg cagttaactg tgggaatact caggtatcgt aagatgcaag agttcgaatc     90960
     tcttagcaac cattattttt ttcctcaaca taacgagaac acacaggggc gctatcgcac     91020
     agaatcaaat tcgatgactg gaaatttttt gttaatttca gaggtcgcct gacgcatata     91080
     cctttttcaa ctgaaaaatt gggagaaaaa ggaaaggtga gagcgccgga accggctttt     91140
     catatagaat agagaagcgt tcatgactaa atgcttgcat cacaatactt gaagttgaca     91200
     atattattta aggacctatt gttttttcca ataggtggtt agcaatcgtc ttactttcta     91260
     acttttctta ccttttacat ttcagcaata tatatatata tatttcaagg atataccatt     91320
     ctaatgtctg cccctaagaa gatcgtcgtt ttgccaggtg accacgttgg tcaagaaatc     91380
     acagccgaag ccattaaggt tcttaaagct atttctgatg ttcgttccaa tgtcaagttc     91440
     gatttcgaaa atcatttaat tggtggtgct gctatcgatg ctacaggtgt tccacttcca     91500
     gatgaggcgc tggaagcctc caagaaggct gatgccgttt tgttaggtgc tgtgggtggt     91560
     cctaaatggg gtaccggtag tgttagacct gaacaaggtt tactaaaaat ccgtaaagaa     91620
     cttcaattgt acgccaactt aagaccatgt aactttgcat ccgactctct tttagactta     91680
     tctccaatca agccacaatt tgctaaaggt actgacttcg ttgttgtcag agaattagtg     91740
     ggaggtattt actttggtaa gagaaaggaa gacgatggtg atggtgtcgc ttgggatagt     91800
     gaacaataca ccgttccaga agtgcaaaga atcacaagaa tggccgcttt catggcccta     91860
     caacatgagc caccattgcc tatttggtcc ttggataaag ctaatgtttt ggcctcttca     91920
     agattatgga gaaaaactgt ggaggaaacc atcaagaacg aattccctac attgaaggtt     91980
     caacatcaat tgattgattc tgccgccatg atcctagtta agaacccaac ccacctaaat     92040
     ggtattataa tcaccagcaa catgtttggt gatatcatct ccgatgaagc ctccgttatc     92100
     ccaggttcct tgggtttgtt gccatctgcg tccttggcct ctttgccaga caagaacacc     92160
     gcatttggtt tgtacgaacc atgccacggt tctgctccag atttgccaaa gaataaggtc     92220
     aaccctatcg ccactatctt gtctgctgca atgatgttga aattgtcatt gaacttgcct     92280
     gaagaaggta aggccattga agatgcagtt aaaaaggttt tggatgcagg tatcagaact     92340
     ggtgatttag gtggttccaa cagtaccacc gaagtcggtg atgctgtcgc cgaagaagtt     92400
     aagaaaatcc ttgcttaaaa agattctctt tttttatgat atttgtacat aaactttata     92460
     aatgaaattc ataatagaaa cgacacgaaa ttacaaaatg gaatatgttc atagggtaga     92520
     cgaaactata tacgcaatct acatacattt atcaagaagg agaaaaagga ggatgtaaag     92580
     gaatacaggt aagcaaattg atactaatgg ctcaacgtga taaggaaaaa gaattgcact     92640
     ttaacattaa tattgacaag gaggagggca ccacacaaaa agttaggtgt aacagaaaat     92700
     catgaaacta tgattcctaa tttatatatt ggaggatttt ctctaaaaaa aaaaaaatac     92760
     aacaaataaa aaacactcaa tgacctgacc atttgatgga gtttaagtca ataccttctt     92820
     gaaccatttc ccataatggt gaaagttccc tcaagaattt tactctgtca gaaacggcct     92880
     taacgacgta gtcgacctcc tcttcagtac taaatctacc aataccaaat ctgatggaag     92940
     aatgggctaa tgcatcatcc ttacccagcg catgtaaaac ataagaaggt tctagggaag     93000
     cagatgtaca ggctgaaccc gaggataatg cgatatccct tagtgccatc aataaagatt     93060
     ctccttccac gtaggcgaaa gaaacgttaa cacaccctgg ataacgatga tctggagatc     93120
     cgttcaacgt ggtatgttca gcggataata gacctttgac taatttatcg gatagtcttt     93180
     tgatgtgagc ttggtcgttg tcaaattctt tcttcatcaa tctcgcagct tcaccaaatc     93240
     ccgctaccaa tgggggggcc aaagtaccag atctcaatcc tctctcttgg ccaccaccgg     93300
     atagtaaagg ttctaatcta actcttggtc tccttcttac atagatggca cctattccct     93360
     ttggaccgta aatcttgtga gaagaaattg atagtaaatc aatgttcatt tcattgacat     93420
     caatgtgaat cttaccatag gcttgtgcgg cgtcagtatg aaagtagatc ttattctttc     93480
     tacaaattgc accaatttct ttaataggtt gaatgacacc gatttcatta ttgacagcca     93540
     tcacagagac gagacaggta tctggtctaa tggcatcttc caattccttc aaatcgataa     93600
     gaccttgatc gtccacattt aggaaagtga cttcaaatcc ctccttcatc atggcccgtg     93660
     cggcttccaa gacacacttg tgttccgttc tagtggtgat gatgtgtttc ttagtcttct     93720
     tataaaatct tgggacaccc ttaagaacca tattattaga ttcggtcgct cccgaagtga     93780
     atattatttc cttggggtcg gcattgatca tctttgctac gtgagctcta gcattttcca     93840
     cagcagtatt tgtttcccaa ccgtaagagt gagtgttgga atgaggatta ccataaagtc     93900
     ccgtataaaa cttcaacatc gtatccaaaa ccctagggtc tgttggtgta gtggcttgca     93960
     tgtcaagata tatgggacga gtaccaaaac ctgtgttttc ttgataagca tggctcattg     94020
     cagtgctacc agaagctact acagcatctg gggtggtacc ggatgcactc gcacgggcac     94080
     tagcctgtgc ctttgcagca gcctgaatat cggtatgcgt ttccagagag aagttgtcgt     94140
     ctaacttcac gcctgctgca ggaggggaat agaatctcct gcttaccaaa caagccctat     94200
     atgtggccgc tggaacgttg taaacttgag ataatcttgt tatcgatctt gtagcagttg     94260
     atttcaacat cttccagttg tagcagttcc ttcgtgtatg cgatatattt taatgaaaat     94320
     gatgtatctg aaatagaaaa tataacacac taatgaactc tgtcggtctt tactctgagt     94380
     gagttactta gatagtcatc atatatccct gggcgatggc cttactattt gtcagcgacc     94440
     gtatctaaaa ttggtaggtc actatcaact attgcgggta atagggtgca taatagtatt     94500
     gtaatatata taaatatata aagctactat gatagatatt tgttgctatt cacgtcatcc     94560
     actattactt tagtggttcc gctatatatt cgcattgccc atcgaaggca gttttgtgtg     94620
     ctacctgctc gtgaccacgg tctttttgcc cagtctttta cggcgggcat acttcatgat     94680
     gaaactgtct attttcatac ctcttgaatt tagttcttca attagaggct tgatatcctc     94740
     caagtcccac tgtgactgta gcctaaacag gactttaaac cgttctttgg ggtccattgg     94800
     tagtgtgctt ttcgctatat actggacagt cttatcggta ggcttgaaat gatagcctcg     94860
     cagcatgtca atgtcaatgt cacatgggaa gaaaggtggg aaaagggact tccacttgat     94920
     gaggaactca tcaattggca tgcttattcc agaaacatat ttccttagcg cttgaatccc     94980
     gtaccactga gctataaacg gtattctcaa gcgccacgta ttgttttcag cctcttgctc     95040
     ttgaacagca aatttattca gcactgtttc aatgatttct cttgtgtatg gattgaactc     95100
     gtcctcaatg tccttcccca cagcgtgatg tgtatcctca acattcagat gctgtagatc     95160
     gagtgattct gccattgcgc tcatcagtag tacatgcagt gctttgaaaa ggaagtcttg     95220
     tgaaagaata cacaacacac cgtctttcac agatccacca atcttatgcc attttgatat     95280
     accttctagc gcagaacatg gtgagttctc aagtagttct tccagggtcc cgataacctt     95340
     tgtagatgac ctcttcatga ttttgtcgga gaaatccagt tctccgttgt atattggtac     95400
     tgaattcaag ttcaattcgc catgtgtctc tctggtctca aattctgatt cagtcttggc     95460
     gaatcccacg acgtccatgt acggcttgga cagtccaaac aagagcgttt cgtcgaaagt     95520
     aataggttgt tcaggaacaa attctctcat tagtagaact gtgtttgaat gtttgcgctg     95580
     cttcagcacc caagtcttgt cgtgcgaaca cagtacaact tcagacttgt ctttgtccaa     95640
     tgacttaaac cttaactggt gattttgaac cggatcctgt attatatcca gtaactctgg     95700
     tgtcaactgg atcagcttat aagatggatc atactcgggt gcggaatgta ggttgatgga     95760
     catggtacag gattattagt gagcaaatct ctggtggatt tttaccgttc atctcatagt     95820
     gcttttttag tttatttttc acttttttct ggttatacta tacgctgcct actgaagcaa     95880
     taagcaagaa acacaacagt ataaagggac aaagataata aaccgcctac tactaaataa     95940
     tatcgctgtg gtatgctact cctagagatt tcgatcacca tcgtggtgct ctttgtcata     96000
     cgcatagaat tgacaaaaaa gaaccctaag ctataaatta ggtcatgttg agcgattgcc     96060
     agttgccaag acctagggtt ttgttcgaac aattctaaaa aggtaaataa aaacaatggt     96120
     aaacaaaggc tttgatcttc aatgaggaag atttctctca ctgcggatag taaaaacaac     96180
     actagtttgt ctgtactcgc attctactgc tgctacctgc tactcattac gtgttcgggc     96240
     tgttatctgg ttgctaaaag agtatattta cacctcacca atggagaaag acctgtcgtc     96300
     tctttactct gaaaagaaag acaaagagaa cgatgaaacc ttatttaaca tcaaactatc     96360
     caaatctgtt gtcgagacca caccgctaaa tggtcattca ttgtttgatg atgataaatc     96420
     actttcagac tggacggata atgtgttcac tcaatcagta ttctatcacg ggtcagatga     96480
     cttgatatgg gggaagttct ttgtctgcgt gtacaagtcc cccaacagca ataagttgaa     96540
     cgctataata ttcgacaaat taggaacatc atgcttcgaa tccgtcgata tatcttccaa     96600
     ctcgcaatac tatccggcca ttgagaattt gagtccaagt gatcaggaaa gcaatgttaa     96660
     gaaatgcatt gctgtcattc tgttacagcg ctatccatta ctttcaccat cagacttatc     96720
     acaaatattg tccaataaat cggaaaattg cgactatgac cccccttatg ctggagattt     96780
     ggctagtagt tgccagttga taacagcagt tcctccagaa gatctgggga agcgcttctt     96840
     tacatcagga cttctgcaaa atagatttgt cagctctacc ctgttagatg ttatttatga     96900
     aaacaatgaa tccaccatcg aactaaataa taggttggta ttccatctgg gtgaacaact     96960
     tgaacaactt tttaacccag tcacagaata ctcaccggaa cagacagaat atggttataa     97020
     ggcgccagag gacgaattac ccacagaatc ggatgatgat cttgtcaagg ccatttgcaa     97080
     cgagttatta caactacaaa caaattttac tttcaatttg gtagaatttt tgcaaaaatt     97140
     cctgatcgcc ttgagagtca gagtactcaa tgaagaaatt aatgggttat ccacaaccaa     97200
     attaaatcga ctcttcccac ctacaataga tgaagtcaca agaatcaatt gtatttttct     97260
     agactcgcta aagacagcaa tcccttacgg ttccctcgaa gtactgaagg catgcagcat     97320
     tactattcct tatttctaca aagcatatac aagacacgag gcggccacaa agaacttcag     97380
     caaagatatt aaattgttta ttaggcattt cagcaatgta attccagaaa gagaggtcta     97440
     cacggaaatg aaaatcgaga gtataattaa gggacctcag gaaaaactac tgaagctaaa     97500
     gttaattata gagagattgt ggaagtcgaa aaaatggaga ccgaaaaatc aagaaatggc     97560
     aaaaaaatgc tacaacaata tcattgatgt cattgattcg tttggaaaat tagattcccc     97620
     acttcattct tatagtacca gagtatttac tccatcggga aaaatcctta cagaattagc     97680
     caaatgctgg cccgtagaac tgcaatacaa atggctgaag agaagggtag tcggtgtgta     97740
     tgatgtagtg gatttgaatg atgaaaataa gagaaattta ttagtcatat tcagtgatta     97800
     tgtggttttc atcaatatac tggaggcaga aagttactac acttcagatg gatcaaacag     97860
     gcccttaatc tcagatattt taatgaactc attgatcaac gaagttccgt tgccctccaa     97920
     gatccctaag ttgaaagtgg agcgtcattg ctatatagat gaggttctag tttctatatt     97980
     agacaaaagc actctacgtt ttgatcgatt gaagggaaaa gattctttct caatggtatg     98040
     taaattatcc tctgcattta tctcttcttc gtcagttgct gacttgatta cgaaggctag     98100
     aattttggaa aaagacactg catttcattt atttaaagct agtagaagcc attttacatt     98160
     atattctact gctcacgagc tttgcgctta tgattccgaa aaaataaaat caaaatttgc     98220
     cttattcctg aacataccac catccaagga gatattggag gtcaacaacc ttcatttggc     98280
     tttttttgca agattttgca gtaacgatgg tagagataac atcgtaatct tagacgtctt     98340
     aaccaaacat gacgataaac atatagaagt tacatccgat aacattgttt tcaccataat     98400
     taatcaattg gccattgaaa taccgatatg cttttcttcc ttaaactcat cgatggccaa     98460
     agatttactc tgtgtaaatg agaatttgat aaaaaactta gaacatcaat tggaagaggt     98520
     caagcaccct tcaacagacg aacatagggc tgttaatagc aaactttccg gtgcatccga     98580
     tttcgatgct actcacgaga agaaaagatc atacggtacc ataacaacat ttagaagcta     98640
     tacaagcgac ttgaaggaca gtccatcagg cgataatagt aatgtcacca aggaaactaa     98700
     ggaaatttta ccagtgaaac ctacgaaaaa gtcttcaaaa aaaccaagag aaattcaaaa     98760
     gaagaccaag acaaacgcct ctaaagcaga gcacatagaa aagaagaagc ctaacaaagg     98820
     caaagggttt tttggcgtgt taaaaaatgt ttttggaagt aaaagcaaga gcaagccttc     98880
     accagttcaa agagtgccta aaaaaatatc gcagaggcat cctaagtctc cagtgaagaa     98940
     gccaatgacc tcagaaaaga aatcctcccc taaaagggca gtcgtttcat ctcccaaaat     99000
     taaaaagaaa agtacttctt tttccacaaa agaatcacaa actgctaaat cttctcttcg     99060
     agcagttgaa ttcaaatctg atgacttgat cggaaaacca cctgatgttg gaaatggcgc     99120
     acatcctcaa gaaaatacca gaatatcttc agtagtaagg gatacaaaat atgtctccta     99180
     caatccctct cagcctgtga cagaaaatac cagtaacgaa aaaaatgtcg aaccaaaagc     99240
     ggatcaatcc acaaagcagg ataacatttc caattttgca gatgtagagg tatctgcgtc     99300
     ttcttatcct gaaaaacttg atgcagaaac agatgatcaa ataattggga aggcgacgaa     99360
     ttcgtcatca gttcatggaa ataaagagct gccagacctt gctgaggtga ctacagcaaa     99420
     tagggtttct acaacatcgg ctggggacca acgtattgat acccaaagcg aatttttacg     99480
     tgcagctgat gttgaaaact taagtgatga cgatgaacac agacagaatg aaagtagagt     99540
     ttttaacgat gacctctttg gtgattttat tcctaagcat taccgtaata aacaggagaa     99600
     cattaacagc tcgagtaatt tgtttccaga gggaaaggtg ccccaagaaa agggcgtatc     99660
     aaatgaaaac actaacatat ctctcaaaac taatgaagat gcatctacat tgacgcagaa     99720
     actctctcca caagcgagta aagtgctgac agaaaattct aatgaattaa aagataccaa     99780
     caatgaaggg aaggacgcaa aggacataaa attaggagat gattacagtg ataaagaaac     99840
     agcgaaagaa ataactaaac caaaaaattt tgttgaagga ataactgaac ggaaagaaat     99900
     attccccact attcctaggt tagcgccgcc agcttcaaaa attaactttc aaaggtcacc     99960
     atcctatatt gagctctttc aaggaatgag ggtggtttta gataagcatg atgcccatta    100020
     taactggaaa cgcttggcta gtcaagtctc cttaagtgag ggactaaaag tcaatactga    100080
     ggaagatgcg gcaattataa ataaaagtca ggatgatgcc aaggcggaaa gaatgactca    100140
     aatttctgaa gtgattgagt atgaaatgca gcaacctatc ccaacttatt tgcctaaggc    100200
     gcatctagat gactcgggta ttgaaaaaag tgatgacaaa ttcttcgaaa ttgaagaaga    100260
     acttaaggaa gaattgaagg gcagcaaaac cggtaatgaa gatgtcggta ataataatcc    100320
     atccaattct attccaaaaa tcgagaagcc cccagcattc aaagttatta gaacatcgcc    100380
     tgtgagaatt atcggaagga cttttgaaga cactagaaaa tatgaaaatg gctctccatc    100440
     tgatatttcg ttcacttatg atactcacaa caatgatgaa cctgacaaaa ggctgatgga    100500
     attaaaattt ccatcccaag atgaaattcc ggatgacaga ttctatactc cagcagagga    100560
     acccactgct gaatttccgg tggaagaact tccaaatact ccgcgaagta ttaacgttac    100620
     aacttcaaat aacaagagca cagacgataa gttgagtagc ggtaatattg atcaaaaacc    100680
     taccgaactg ttagatgatt tagaattcag ttcatttaat atagcatttg gaaatacctc    100740
     catgagtact gacaatatga aaatatcatc cgacttaagt tcgaataaaa ccgtgttagg    100800
     aaatgctcag aaagttcaag agtctcctag tggaccatta atctatgttt tgcctcagag    100860
     tagcacaaag catgagaaag aggggttcct tcgaaagaaa caaaaagacg agcccatttg    100920
     ggtttcccct agcaaaattg actttgctga tctaagtagg agaactaaag cattgacgcc    100980
     agagcgtaat actgttcctt tgaaaaacaa cgacagtaga aaatacaaat atactggaga    101040
     gggatctatc ggtaatatga caaatatgct gttaactaaa gatgcttcgt acgcgtactt    101100
     aaaagatttt gttgcgttga gtgacgatga agatgaagat gggaaacaga actgcgctgt    101160
     tggtggccca gagaaactga aattttattg agtgttttat tgattttttt tttcttttta    101220
     atttaatgca atgtatacat ttacataaaa tatggacaaa taagaaaaag ggggaaaaac    101280
     ctcccactta agtaaaactg aatatattag atacctttac ctactatcaa aggtgaatgc    101340
     ttttggatca ataggggttc catcgggggc aataccattt tggccgaact ttctttccat    101400
     atataatagt ctagccttat cgaaatctac attatcgttt tccataattt gtttaatctc    101460
     attcttggag acatcatcca aaccacctct tacgtcgttg ctattctccg agataatatc    101520
     gaaattcctg gaatggagac cgttttctag gtcatcagca aaggaatcat ttaaacgtat    101580
     atgtctatta aaacgtaatt gtattcttga acgcagtgca cgaaatttgt cggctattac    101640
     agctgttagt atttagatac ggtttgcact ttgcattttc aaatgcttaa atatacatac    101700
     caactttggt tttccggtgt gccataagaa ggcataaaga caatagcaca acccagagga    101760
     gcaatttgag atagaacaaa ctcttcatac tcgtatttgc aatttttgga aattaattgt    101820
     gtagcttttc ttctcttaat tggtggcagt ttttatatat tcagtttaga ataccctttt    101880
     tttttttttt tttttcttcg cttttcgcat ctcatcgctg gaagtggtgc tcttttacag    101940
     ggattaaata aggttattct ttttggtcaa aatgataaat ataactatta aagttattta    102000
     taacccgccc gcttccttat tatttatacg ttatcataaa gtacacaggt catggttcgg    102060
     ttggtgctta ggaattaatc acgtctagca taagagatct gtaaactaca accaccataa    102120
     ttataattat ttaatttttg aatacaaaaa tctgcatcta ctaaattttc atattctaca    102180
     acagcaacac cagttggttg accattttcc tgtggtttca attccgcgtt attgattttg    102240
     ccgataggcc caaacaagtc gaataaatcg cttcttgctg ttgagaatgg taaattacta    102300
     caataaatga aacagtttct atcccctcct ggattgacac cttcagtaaa ttttgctgca    102360
     gtttcatcaa tgtggacagc ggcatcctgc gcaagacctg gttcagtacc tctggtatct    102420
     tcaaggtcct cacgcctttg attataacga tcattgttct ttctcttgtt gaaacgccct    102480
     tctctaactt ccaaaactct accttctact tccatgccgt tgaatgtatc gatagctcta    102540
     atcatttcat cctcagtagg ataaatgaca gaaccgaatc ctcttgaaaa tccgttgaaa    102600
     tccaattcta catcggcacg caagacatga ccacattctt taaacatatc ttttaaggat    102660
     tgccaattca tagagtacgg taaattgatg atgaacactt caaacccatt atctatttct    102720
     tccctagtag ctttcttaga aaattccttg gcagcttcag gaggaggatt atcctgtctt    102780
     accattagtt tccggtccat aaagagggca ccatcaaact tcgatatggc atcttggaca    102840
     gattcgtttt tggtaaattc cacagtcccc ataccacggt gatggccctt tgatgtgata    102900
     atgtcagcct ccacaacttc gcccactgta ccaaacaatt ccttaaggtc ttcaggggta    102960
     caatcaaaag tcaagtttct cacgaagata ctattttcaa aatttctctt ggtcgcgtca    103020
     aattgccttt ctaagtctct ttcaacaatt ggacctaaag tacgacccct accgccaccg    103080
     cgtccccctc tgaatgatct gcttcctcct ctgccacggc ctcctcggcg agggggccag    103140
     ttcctatcat cgtggtagcg gctgccacca taactctgat cgtaccgatc attgaaacgg    103200
     gagcctcggt cgcgtctctg acgacgactg ccattaccat tattactgct actatcgtta    103260
     taatcatcgt acctgtctct gtcgtcgctc aaacgacgac gtacaggtga tcttgatcta    103320
     ctcctatcat ttccatacat ccctagctct ctctccatct tggcgaaaaa atccagctga    103380
     tgtttgtttc cttttcgccc atagcttatt tctaatggga aatcctcaat ataattgatt    103440
     tcatccaagc tttcattttt tttcaatttt tttcaccttc aagtgaatac atcacttccg    103500
     acgataccaa aataatgaca aaatgccatg agaagatctt atgatatgta gtaaatgtta    103560
     accaccattg ctatttcctt gctaggtttg ccaaagccgt tggcgaaggc agcactagac    103620
     ggcgagtcac ttccgtctct ttgtccactt cctcttcacc atcaaatcga agcctgcaag    103680
     tgccgtccct cttggttccg atgacaattg caggataaaa agtggtcgtt tcaggatatc    103740
     ttgccagaac cttagtacct ggcgggtagt tcttagtggg aaagcctggc gggatcaaca    103800
     gtagttcttt ccgattacat ttatacacct tgcctgagtt gcccaattca tcaggttcag    103860
     gatctctcac ttcaaatcgt gtaccatctg ctacgacttt gagtacttca cactgtatcc    103920
     attcgccgtc ggcactgccc cttctgggct tataggcaac ctctgagccc accaaaatag    103980
     gtgcatttgg gttgtattcg ctggtccagt acgatctgcc aactttcccc acagctttct    104040
     tgccctgcga caatgccatg cgtgtccctt ctccttcttc tgcatcttca gtattttcct    104100
     cactcttttc ctctcgtgac tgattcaaca tcaacgacaa attggaacgt acattgtcaa    104160
     ggattcggtg cactctgttg acgttttcca tgtgttcttg gaaagtgttg agatgcaatt    104220
     gcagctgatc ctttgacata ttaaggaaat ttagtttttt tgtttgcagc tcatcatcaa    104280
     agggaatgac ctcgttggca ttgtatatgt cttgcaagga cgacactaca acatcccaat    104340
     atccgtccat aataagaaag gtgaccgtgt gttttgctgt gaaaaactcc ccccacttag    104400
     agaagccacc aaggtattgt gtctttaacc tttttcgtat ctggcaaaat cgaagaggaa    104460
     agcagaaaac caaaagaaaa aaatagttta gtaacgcgtc acctcgtaca aacgtacaat    104520
     catagcaact tatgagtaaa taggctcatg gttatagata cgttatatag atgtatagag    104580
     gagagtcccg agggcgatcg caaggccgag agactaacct aaccaggtgg tagttgggaa    104640
     atgtcgacga tttcgctgat cttttcgtct tcgtcggcag cttcctcggt gcttgtcttc    104700
     aaaggagttc ttggcaatgc catcataccg cttcttgcac actctaggac accgaatggc    104760
     tcgaccaact tcaagaaggc agagatacgt gtgggttttg cagacaactc cacaatacag    104820
     cttgtttcgc tgatgtcgac gacacgacct ccaaagttgt tggtcaagtt ggtgatatcg    104880
     ttcaaatgct cgtgcttcaa ccttaatacc tcactggcgg gcaagttggc agggtggaat    104940
     tgcttttctc tgatttcggc gaccaattct tgggagtcag cggcgccagc attggtggaa    105000
     gtgtggtggt gcaatagtag gtcttcgaag tattcagtac ccaatagaga gattctggcc    105060
     atcactagct ctcttttgat gatctcagaa ttggtatagt ctaggacggc gtagacgggg    105120
     accaagtctt cgatttgtct gcgtgcttgt tcgactacgc catcttgccc ttgcaaaaca    105180
     atggtcattc tacttaggtc tttgacctcg gtgttgcaca cgaccaacga atcgatgtta    105240
     aagcctctgg cagctaacgt acccgagact ctggacaaga caccgggttc gttttgcacc    105300
     aaacagttca agacatgctg ttttcttggt tgacgagaag gcgctggtgt ttcgtaaatg    105360
     atggatgaaa cggcactgtt ggcattccag gaaggagtgt ctagtgtggg caagggaggt    105420
     cttgttgcgt gtctgtgcat ctgcttgtac gccaacgcgg aggtcgacga ggaactgcaa    105480
     cgcaccatgg tagcacatga agaagcaacc accctgcggt ggccgctttg caataacgat    105540
     ctcagcatta gaaagactgg gttagtgagc tcagatgttc taaagattct gtatatacga    105600
     actatgtact tccatatata ccattccccg ttcttgttag gtaaaggtta aaaaaatatt    105660
     ttttatggca cttcggcgat gcgaaagaaa gtgagtcacg ataacggtga ggtgattcgt    105720
     tggatgtgcc atcgcacaag gaattgctgg cgtgctaatt cacgaccttg cttgacaaaa    105780
     gtatcgaggg gaatggtgcc acggtgcagc atcctagata agcactcaat ggtgtccgtg    105840
     agagcgtagt cctgggcaac gaggttgtat agttgattga gtccatctgt tttggccact    105900
     gctatggagt tcacgtcctc gtcatccaca tgcgaagttg agctaaactg ttggactttg    105960
     gccctatttg cggtcaggac gtctatctgt gcgtttagcg agtgcatggt ctgctcaata    106020
     gcctgctcaa cggctcgtaa atggttcttg tcgatggcga ttatttcatg gaatctggca    106080
     attgattctt gcatgacggt ctgtctcgtc agtatcttgt ccgctacata gtccacatcc    106140
     tctctgtata actcattgac tacggtttgt agattttgta gcatttcatg atggttggtt    106200
     ggggagatat ccgtgttgtc catgtccata aggtcgagtg cgttagatgc cggttgaggt    106260
     ggtggaggtg gaggcaatgg cggttttagg tgtggagact tgggctttgg gggcagtggg    106320
     ggagtattct gctcctgctg gagctgcgta ttgggcttag ggggtagact gggcgcctga    106380
     tcttgtggcg gctcgtgtaa gagactcatt aattcttgta cgaccattat aaggttcatc    106440
     gcggcaggat cccagcagtg gagtatgggc agcgcaatcc acccattgga gtcgatgtat    106500
     tcttgaatgg gcaaggaact actgatggtg ttcatgtcga aattttccaa gtttatactt    106560
     ataaagggag gttttaccgg gtacatactg ggtacccaca tgatcacagg aatactgtga    106620
     ggagatgaac catcctcacc agtactaatg gtaccatata tggacaacag tagttgtgga    106680
     gtgccgtcag agtgcgtaaa tacccttgtt cttggcctta aactgtgaaa attgtccagc    106740
     agcgctaaag aatcgtggaa agttgttctt ccgtcgttat aaatgggttg aatgactttg    106800
     aacagccaat tgaccaccgc ctcgggaaca gagatcttgc cgtttgcaga catcgttgct    106860
     cttcactctc tctcttttct tggccgttaa gataccaact gcccacaaaa ttttgccgta    106920
     actttttatt ctcgctctgt gaaaaaagac tactacattt tttgaccttt tatctatact    106980
     ttaagaaaca aaggtccaac gaataataaa gaacaaagag taatgagtag tttgtatgtg    107040
     tcataatctc ttctctccgc ttcccttttc ttccttcttc ttctactaac tctctgcgcg    107100
     tccaatttag ctatactgtt gttggtgtat tcatagtggt tagtgccatg tccgtgctgt    107160
     tctggataat ggctccaaag aacaaccaag cgtatgtgca acattttttt tacgatgtgt    107220
     ctccatatta ctagtttccc tttctttttt actaacaaga gtttgtttgt tttgttttgt    107280
     cgtacagtgt ttggagaagt acagtgattt tgacattggc catgatgttt ttgatgtggg    107340
     ccattacgtt cctttgccag ctccatccct tggtggctcc acgccgttca gatttgagac    107400
     ctgaatttgc agaataaagc gtcgagtata tcaagccaag tgacgtttcc tgagtataag    107460
     aaaaataagc aaaataagta tacataaaaa taaatacgaa tagaaatata gtggcatcta    107520
     aacaacccag agattttttg aaaaacacaa tgagtatata ctgatagaca accacacggt    107580
     ctttgaaacg agacgccgtc tacggttgta tcaaaatgtg taaacgggcc atttcaaagc    107640
     ttgatcttct ccataattag aacccatgtc ccgtggaagc gttttaaaag acatgaggca    107700
     gaaacaggag tgtgatatcc ttgcatgcgc aagttggtaa tacactgcac aaaacacgcg    107760
     tgtgcacata cacttatgtg gttcaccgtg ccgctgctgt gtttatctgt tgctcgacat    107820
     gtgctgctaa tgattatgtt ggaatagaca aacaatttaa agtaatttct tcttttttta    107880
     tagtgagaaa tctcaaaaga aaaaaaaaaa aataaaaaaa actaaagagc tgccgggtga    107940
     gcaacgacta aaagaagaaa ccatttaggg cttcatcagc aactgtagga ggagaaagca    108000
     ggtatataac tagccgcaat atgtttgtgg tggattggag cgtgcagcta tgcatgggag    108060
     tgatttcacc tctcttccgt gccctcgtgc aactgccttt atcaattttc gtatggaatg    108120
     ggtttcagct tgtggcattg cctatcaaca tcccattgag gttgttcctg gggacgtcgc    108180
     tgagccgttt agttgcacaa acaagcacat tagacttcta tgtggttttg acgttgtttc    108240
     aatattttgc tgtgctttgt gcttttggca gcatcatagg actcatcttt ggatttatat    108300
     tgggtgtgtt ccactcaatc tgcggggtac ccagtgtata cataagtcta gaatggaaac    108360
     ggtggtttgc tccgatacgt acggtccttg aacgtgcttc cactagtatt gtcaacatta    108420
     tgcgaggaca aactattgcg ccaataccca tgcctaagcc caatcccacg catatatcaa    108480
     agcctaacat gaaaaaattc catgatgagc ctggagctga tgatatgact ataacgcatg    108540
     atgtgaactg ctacatcacc ccttgccaaa cgcctactaa cgaaaaaatt cagcattata    108600
     ataatgattc attcaacacg accaccacag acgatgaacc cactgatatt tgggataggt    108660
     ctgacactta ccaaaactca ttcgtcacca atgaaacttt gatgtctctt tctaatagag    108720
     ctaagcttcg aagaaatgcc agtgatgcgg acatcgttaa tataaagatt ttacgaagga    108780
     attctaggtg atattgcaat tacttcttct catgcactaa caagtgaatg atagaaatat    108840
     gttgagttcc taactgcctg attttaaata agtttcatat tataatcttt tagcatatat    108900
     atatatatat tgatcctctc tcttctttat tttctgccag taacccatgt gtgaagaaga    108960
     aaacataaat aaaaaagcag tagcacatgg acacattcac gcccgaacac tcctaaaaag    109020
     cagcccacac aagaaagtag atataatgta ggacacccag cttgtccata attgctaata    109080
     gcatactcag gataacatat attaatgacg actcgtttgc tccaactcac tcgtcctcat    109140
     tacagattat tatccctacc tctccagaaa cccttcaata taaaaaggca gatgtccgct    109200
     gcgaaccctt ctccatttgg caattatttg aacacgatca ctaagtccct acaacagaat    109260
     ttacaaacat gctttcattt ccaagcaaaa gaaatcgata taatcgaatc tccatctcag    109320
     ttttacgatc tcttgaagac aaaaatactt aattcacaaa atagaatatt cattgcgtct    109380
     ctgtatttag gcaaaagcga gactgagttg gtggactgca tatcccaggc attgaccaag    109440
     aaccccaagt tgaaagtttc ttttctactt gatggccttc gaggaacaag agaattgcct    109500
     tccgcctgtt ccgccacttt attatcgtct ttagtagcca aatatgggtc agagagagtg    109560
     gattgccgat tgtacaagac gcctgcttat catggttgga aaaaagtctt ggttcccaag    109620
     agatttaatg aaggtttagg cttacaacat atgaaaatat atgggtttga taacgaggtc    109680
     attctttcgg gagccaacct ttcgaacgac tatttcacca acagacaaga tagatactat    109740
     ctctttaaat ctcgaaactt ctccaactat tattttaaat tacatcaact cataagttcc    109800
     ttcagttatc agattataaa gccaatggtg gatggtagca tcaacatcat ttggccagat    109860
     tcgaatccta ctgttgaacc gacgaaaaat aaaaggctgt ttttaaggga agcatctcaa    109920
     ttactagatg gctttttaaa gagttctaaa caaagcctcc cgattactgc cgtgggtcaa    109980
     ttctccacat tagtttaccc aatttctcaa ttcactccac tttttcccaa atataatgac    110040
     aaatcgaccg aaaaaagaac aatattgtca ttgctttcca ctataacaag caatgccatt    110100
     tcttggacgt tcactgcagg atacttcaat attttgccag acatcaaagc aaaactgctg    110160
     gcaacgccgg ttgctgaggc aaatgtaata acagcttccc cctttgcaaa cggcttttac    110220
     caatcaaagg gcgtctcatc aaatttacct ggtgcttact tgtacctgtc aaaaaaattt    110280
     ctacaagatg tatgtaggta cagacaagat catgctatta cattaagaga atggcaaaga    110340
     ggcgtagtaa ataagccgaa tggttggtca tatcacgcaa aaggtatttg gctttccgct    110400
     cgtgataaaa atgatgctaa caattggaaa ccctttatca cggttatagg atcttcaaac    110460
     tatacgagaa gggcgtattc attagatttg gaatcgaatg ctctcattat tacaagagat    110520
     gaagagctaa gaaaaaaaat gaaagcagag ttagataatt tattacaata tacaaaacct    110580
     gtaactctag aagactttca atcagaccca gaaagacatg ttggcactgg tgtaaagata    110640
     gctacctcca ttttgggtaa aaaactttag attctattct atcatagtat gtcgcctgta    110700
     aatatggaaa aataaaagaa aaaatagtaa taataaatgc attatctaaa actccttaaa    110760
     tttgcaaaca tcgcaaagcc attaaggtag agaatgagct gaccttgtta tagttttcct    110820
     tttggcaacc gtggtttccg tcctacgtaa acatactgaa cttgacaaag tatgaccaat    110880
     aaggtgacaa attgtatcaa ttttacccaa aagggcgttg aattaaatgg tatctcgtaa    110940
     aacaatgcat tggtcggtat taccagtcta cctaataaat cgatagattc agccaaaaat    111000
     gatatcaatg caaactttga tgataaacct actgttgagc atcccatcca gtttatactc    111060
     atttgaggca catacttgaa acatttaagc agatttgcca ttacccacaa ataatttatg    111120
     tgttccaaat agaaaacgcc aaatttacct gaatttttca acggtaaatt agagatggaa    111180
     cagccatatg taaatatgcc taatacaagg aacacactta taattattat ggaagtaatg    111240
     gaaatgccct gataaatatg tttagttgac ctataatagt ataactgcct taaaaccatc    111300
     atgcagcaac aggaaacgca aaaatctttt agaatgagga aactggatat aggtatacta    111360
     cgggcatcat tcaacggata aaaaagtggg aatctttgag acagttgttc cctcaccaga    111420
     gatgaataac aataatgcaa cgcgcaatac aagtacagac cattaccaac aaaatctagc    111480
     agaaataaat catatgaaag cccgtaaata gatcgatgaa gtttattata gcgcttttga    111540
     catagaatgg cgatgatcta tgtaagaaat ggaagttttc tcccttagtt agtcaaacct    111600
     ttcatgtata ctttctcctt caattatgca tactgataaa aaacctgcca agccctgcag    111660
     aacaataaca agcatgtgaa tgattcaata taattgcttc gcagggctcc tcaacctctc    111720
     ctctggaaaa ccttacctca atgaggttaa aaattgtggg tttttcgttc gcagaggaaa    111780
     aaaaaacttg tcaaaacacg cctctgcagt agaacacgaa ttatacataa gaaaaataac    111840
     gatacaagaa aggcgatttc gatttgggac taagtgttac acgaaaggca tagagtatca    111900
     aaaaaaggaa gcaagatgga ttacgatagc tctgatacaa tgaacggtgg ttcaagtaac    111960
     cccttaatca ctaagatgaa tacaatgaaa ttattatatc aacactattt ggataaagtc    112020
     actcctcacg ctaaggagag gtgggctgta ttgggtggtt tgttatgttt gtttatggtt    112080
     cgtattacaa tggccgaagg ctggtatgtg atttgttatg gtctaggtct atttttattg    112140
     aatcaatttt tagccttttt gaccccaaaa ttcgatatgt ccttacagca agatgaagaa    112200
     aacaacgaat tggaagctgg agaaaaatca gaagaattcc gtccattcat cagaagatta    112260
     ccagagttca aattctggta taacagcatt agagccactg tcatttccct cttgttgtcg    112320
     ctattttcaa tcttcgatat tccagtattt tggcccatct tattgatgta tttcatatta    112380
     ttgttttttt taactatgag aaggcagatt caacatatga taaaatatag atatataccc    112440
     ttagatatcg gtaagaagaa atattctcat tcttctaact gatataccct gactccacat    112500
     acctattcaa cgaacacatt cgtatcttaa ttatatgtaa acaaaattat atgatagtta    112560
     cagaataatt gtgattattt tctccttcta ctcatcttct cttatattgg aagaatacat    112620
     gaagttattg attaagcaaa attgaaggga agaggctcat tttcttccat ttataaatgg    112680
     agagcttgag atgcctccaa ttgataaatt tttgtaaaga ctttcaagaa acatgtctaa    112740
     aaagaattga cagcttcgaa cctttctgca taattactaa taccaaatta gtgagaaatg    112800
     gggtatgtcg aggaataaag gatgcaaaag agagagtaat gtcatgcaag ttgtgagttt    112860
     gaaatgttca cacgtttata atgtccatac tccgtggcgt gcatgtgttt tagtgtatta    112920
     gttttccaag ttattaaaga acttagtaaa tttatcatcg aacgcatttt gattaagtgg    112980
     cacaatagac ttcaatggaa aatgaaaatc atatctgtag caaaaacgac agcgaagata    113040
     acggttacac aattatcacg ttgattcgtc aacttaaaga tgaccttttt acaatttatc    113100
     aataataata gacaagaagg acaaggttat atttcagaaa aattattcaa aactaagaag    113160
     aatgagatga taagaaaaac agttaccaat ttagtagctg taagattaaa aaacttatcc    113220
     cacgaatttg atgtaataga gaattatctg cgctatatag ctagcaccag tgaacatcta    113280
     tttactgcta ttaagcgcca ctttaacaaa tgtgccagaa aacttttgaa agaagcaatc    113340
     gactccaaat caaactcaga aactgctacg gtggttctgc aagaaggatt ttctggcatt    113400
     tgcttattga aagcgtcttc aattatatta aaactaaaat tgaagtttcc aaaaaagaaa    113460
     gatagaactg atattagcaa attgtgtgac aagaaagaac ggatgacaca gtggttagaa    113520
     atttcaattt tgatgaactg agaataataa tattatgctc ccctggattt tatgcgaaga    113580
     cactgctgaa aaaatttctg atatatgcag agaaggagca aataagccag ttttaaggaa    113640
     ccgagataag ctgttttcgc ccattgttct agttctacaa aatatctaca gggaatcgat    113700
     gaggttgtaa gaaatcctga atactctatg atagtgcata acactaaaaa gttgaaagaa    113760
     tcccgtatca tggacgattt ccttgaacat ttgagcaaag acgataacaa agcatggtat    113820
     ggcgcggaag aaaccgagag agctgcaaaa ttagatgcaa tagaaacact acttattaca    113880
     gatagtgtac taaaaaggaa cgacgtgaaa aaacgtgaaa aatacctaga cctaatagag    113940
     aatagtggaa acaacaatgg caaaatattc gtactcagta cttcaaaaat cacagtgagc    114000
     aacttgacaa accaacagat ataggctgtg tcttaaaata taccatccaa taccttgatg    114060
     aacttttcaa agatgactaa aataagtgaa atttcaacat taacttcgaa tttttttctt    114120
     tttatctaac acttgtcaaa cagaatataa ggattacttg tcttctttgc tacatattgc    114180
     taccacttct attacacaat agtttcaata gcttgcagcg tagctaaact ctaaaattta    114240
     tctaaatcac tcatataaac cgaacccttc cccttccgct tatagtacag tacctataca    114300
     tttcataaac atggcatggc gatcagcgcc aaacaatatg gaaaatccac agaaagctat    114360
     tcattgaaaa aatagtacaa ataagtcaca tgatgatatt tgattttatt atatttttaa    114420
     aaaaagtaaa aaataaaaag tagtttattt ttaaaaaata aaatttaaaa tattagtgta    114480
     tttgatttcc gaaagttaaa aaagaaatag taagaaatat atatttcatt gaatggatat    114540
     atgaaacgtt tactggtgga agttttgctc atatattatt attcaataga agtaataaag    114600
     aaaaagttgg taaagcaact taacagtaaa aaggtaatga ttgaaaaagt ttttgaacat    114660
     ctaagctata tgttgatggg tttacaattt taccattagt actcatgcct atacttttct    114720
     gttcgtcctt aatgtccgcg atttagagca atcattgaaa gtactagata cattttagcc    114780
     agagaggact cgttgacgta gaattaaaat tcaaatgaat ttccgcccca ttcatatacc    114840
     ccaaataaca aacatattaa aacttcataa ttattcaaaa tgtggagtag tatagaagag    114900
     cagtaccttc aaaattgatt tcttcagttt cccacccggg atccacttgt catgcggtga    114960
     gaatcgtata ttgcgtataa tccgtgtttc atcacccaca ttatagtaca aacctactgg    115020
     tgtaaccatt atcatattca tgacttgtag ttaaaaatct ttcacgataa attgaggaaa    115080
     aaatcacgtt aaatagtttc atatcattct ttagttaaag tctgtgcata aaaagaggat    115140
     cgggtgttgt actcgttcta tcaaaatatt gttattgttg cattatcaca cgaattacaa    115200
     tcaatttttt tatctacagg ccagagtacc tgaaataatg gaattagatt caaaaaggat    115260
     agcttaatcg gtctttatac taattatttt acgcccagaa cgaaacataa cgtgcattaa    115320
     atctcactgt cacaacattg tatataatgg tagcatcgta ctaactattg gcattcattc    115380
     aatattatac aattatctta ttaatacttt ctcaagtagt cttgaagacc agcatgtagg    115440
     aaggtgatga tatgctccgt aaataattgg aaatattgag atataataac gatgacaata    115500
     ctaacaaaag taataggtga gctccgccaa ttgattgttt tgttttgaat atatattgat    115560
     gcttaacaat ttagtcgtca aatagcacct gcaaaaccta cctcttacag gctttttttc    115620
     aatttactcc ccatgtggga gttctacgta aaccacttag aatgcagttt ctcttctaaa    115680
     taacatgtta tatcttctga agaaattgaa acatattgat tcttatggtg agagcaattt    115740
     atcaatgttt tatcttaagt tctactgccc ttggaaatta tgtcctttgc ttcccatttt    115800
     atatggaaga aacaaatcag tacaaaatgc ttggtcatgt cataagcttc atcgatttat    115860
     tgacttccca actccttcgg ctaatatgaa tttttttttc tttataagag tttgctatgg    115920
     aactgtctcg ctgtttattt caacgtttct aaagaaaata tcctttttta tttatgtgaa    115980
     cttcactgta tacttttagt acctttcggt ggatttcttc tattttactc gatcactttt    116040
     cttgactgtg cactgtcggt acaatcctta ttgtattaac ttgcgaagaa tatttagtcg    116100
     ttcagtaggg ttcttttgga agaaatgcta gcttaacatg agtgtgatct cttctagaat    116160
     taactctttt gtttatccat gtaatctgtt accaacacat aaaatgcatt gatagaccaa    116220
     atatcaaaag cgtgcaggca tctcttatct aacagtaagc aaaattttgc ctgcgcttta    116280
     cttcaatttt ccattctttt tctgagtctt cgtcagtgca tattttttta ctgacagcac    116340
     cattaatcaa tcagctcacc tgcgcatttc caataatcgt gctcatgaag atcataaaga    116400
     aacgtccaaa catgaaagtg ctcctttaga atttctaaat ccaaacgata tatgtacccc    116460
     tcgttgattt gtcctaaaat gagtatagct tgattttcgt tatatatttt ttcatagtat    116520
     tcagaagagg agagaggatg tgatttatca atatctgcat taagtaatga actttgccct    116580
     ctactgagga tattcccact agaaaactat aaaaaatggg agaaagtcaa tcgctgttca    116640
     ggattcaaca tagttgttga caacgtatga taagaaggcc agtccagtcc tcctaagtta    116700
     ggttaaggga ggtagggaaa aactgaagtg taatgataat cgaggatgaa agtgtgcggc    116760
     cagaaaaatc ttttcttttt atattaatct gtaataaata caagacctat atattaaagt    116820
     aaaacaacat tgaatcagat cgcatactgg tgtagacgtg aagtagacat atgataatcg    116880
     agcagggtgc tcaatttggt gtgggacacg tttgggaagg ttaaaagaag aggtatatcc    116940
     ggattacatt tatttttggc gtattttaat aatttactaa aagcgcgaat agcttcccat    117000
     tagcaacgct cagggactct ttctaatgtt tatagtaata ctttaataag atgagtacca    117060
     attgcttctc tatgaggcac aatccctaac caaactttta tttagaatta ccggtaaact    117120
     ccgttttctt catagattaa atatttggct aagacaacaa aatgttcttt cattttacca    117180
     aacgagaagg tgatagctgt acgccagaaa agaaggtaaa aactctcgcc aatccagcaa    117240
     tacctgtacc tctagttttc gatcgcatta tgtcattatg taaaaccaag gagagaagca    117300
     agttacggtg ttttcatata gaataatttg agaattctta ataacataag atatataatc    117360
     accaccattc ttatgagatt caacgttgaa tggcgttgct agacatatga gctgaggaac    117420
     gactattcgc attttctttc aaggcaatta attgtcttgc tctgaaccct tcataatgaa    117480
     tgtaggaagt tgtttcgatt aagtcttgga gatgagttcg aatcaaaaat tcccttaaat    117540
     atacaaaatc acactggttg atatcctcaa cattaatagc gctccaacga gtttttcttc    117600
     ccctgaaggt ttcaccgttt atttcaatct cattctcaga accaaccact gcaaacggaa    117660
     tgatagatct aacacttctg tttagttcta attcctcgtc agttagttct tccgaatcat    117720
     aaggataaat cttgaaattg tatttttcga attcattttg aataagctcc ctaaactccg    117780
     ttctttcatc taaagtcaat gtatccgact tgccaataac tggtataaca tttgctattt    117840
     ctgtcaatct tttcaaggct tcaacgtcaa ggcggctcaa ctcctttcca tttggttgca    117900
     ggaaataaag aattgcatga actcttgtat cagtaataaa cctttcacgt tgggctgtca    117960
     attctttacg taagtattga gaatgttgtt ccttaatgta cttcacaata ggctcccaag    118020
     ctttagaatt gtcaataaag tcaccaaatc caggtgtatc tataacatta atattcaagc    118080
     gaacgcggtc ctccacaaga gtatgagtag aaattttcat ttcagttgtt tttgtaacag    118140
     gcagggcaga aatatcatca ccagtagcag aatcaatcaa atgtgaggca aataacgtat    118200
     ttattagagt acttttaccc aatccggatt ggccaacaac cattatatta aattgaaaac    118260
     ctttcttcaa cagacgatgt tcgatctgat tcgtgatggt atcaaaacca acataagaag    118320
     caggctgtac tgagctgaga ggatccatta atatatttat agagtgcttg tagtaaccgt    118380
     ggggcttggc cttgtatttt cttgtctttg cctgaaaaaa gttaagtatt actgatacat    118440
     gtttacatat attctattca gcgattctga tctatttgtg gtctctcgag gaaatctcat    118500
     cgtatcatac gattatttcc gcaagcattc agaaagcaaa tcttaatata aggcacaatg    118560
     ttcccaaata ataccttaac ttggagacaa aaacaccagg gaatatcagc aaacaaacta    118620
     tgaattcttt gatttttggt aaacaattag catttcacaa aattgtgcct accactgcaa    118680
     ttgggtggtt ggtaccgcta ggaaatcctt cactgcagat tccaggccaa aaacaactgg    118740
     gatctatcca ccgttggttg agagaaaagc tacaacaaga tcataaggac actgaagata    118800
     aagatttttt ctctaataat ggtattctac tagcagttcc taaaaaaaaa gtatcacacc    118860
     aaaaaaaaag gcaaaaactt tacggtccag gtaagaagca attgaagatg attcaccatt    118920
     tgaataagtg cccatcatgc ggccattata agagagccaa tacactgtgt atgtattgtg    118980
     ttggacaaat aagtcatata tggaaaacgc ataccgctaa agaagaaatt aagccgagac    119040
     aagaggagga actttccgaa ctagaccaaa gagtcctata tcctggtaga agagatacca    119100
     aatataccaa ggatttgaaa gataaagata actatttgga acgtcgcgtt cggactttaa    119160
     aaaaggacta ggctcatctt tcatctagtg gtttcctttt taaataaact taagcctgta    119220
     tatagaaact taatttcaaa ctgtatattt attgtttaag acagcatcaa tggtagaata    119280
     caaggagcgg aaacagaaag aaaagtcgaa atagaatttt tcgcttttgg cttaacaaaa    119340
     tgaggtcttt gaaatcaaga gttttgcttg acaaaaaaca actatatttc aaaatattag    119400
     gaaatgatat tattagtaca aggacttaca gaaatatact tttaatataa aaaggaaaaa    119460
     ataaaataaa aagagttaat tctttattaa ttttccaacg tcctacattg atatatctgc    119520
     tgagatagaa ttaatgttag taagaactaa atattagacg cgaactgttg tttcttacat    119580
     gacagtacag caggataata atcctttgtc ctccttcttt tctgcagttg tagctgctgc    119640
     aggtttagtt tgtctcttag ccgcatcaga agtagtggtc ttcttttcag tggagggctt    119700
     ggcttctttt gcagggaaaa gttttttggc ggtttcgtag aatgttttac cttgaatttc    119760
     agcaattctc aattcaagtg gagacgcagt tcttgagccg tcaggtcctg caagggtacc    119820
     agcaccccat ggagagccac cgtgtacctc ttctatactg gctaactcag caaatgaatt    119880
     cttataaccc agtggtaaaa agataattcc gtgatgagct aaataagaca aacaggcttt    119940
     aacggtactt tcttgaccac ctccgtaact ggaagtacta acgaatatcc ccgcagcttt    120000
     gccgttcaaa gagcccttgg cccataatcc accggtttta tcccaaaagg cggaccattg    120060
     agccggcaaa ttaccaaacc tagttggaac accgaacaaa aaggcgtcat attcgagcaa    120120
     cgttttctca gtggcaacag gaatatcttc aggtttctga ggagcgttca tcttggtgag    120180
     gacttcatca ggtaaagttt cctcgaccct gtatatatca gctttaccac cagctgcctc    120240
     cacacctttc ttaacagctt gggctaaaac gtctatgtgc ccgtaggtag agtaagtaat    120300
     tatcgcaatc tttaccattc ttatagtgct tcaattgagt ctgtattgtt ttgtttactc    120360
     tctttttttt tattgatact aacctgaccc ctcttttcct ttttcctctt cttgttttct    120420
     ttctgataaa gtttacaaac ttcaaataaa aatgaacgta aaacaagtaa aaatgtagga    120480
     tgttatagta tcaactagct gccggaatag tgcaaattgt atgaatcgaa ataagtacgc    120540
     tagccaaggc agtaaggcct aatgccctta ggcaaattta ttatttatat taagttccaa    120600
     gaaggggaag cgccttcttt ccccgcagta cagtatttta cccggaggtt cttaataagt    120660
     tattactaaa agggtcataa cggatttatt aataatggga ttataaaaat aatgcgtgtg    120720
     tacctagtta tcgcgtgata gcttccgcaa ttttccaacc attagtaaat tttatgtaac    120780
     taaaacgagg aaggaaatag taacgttcat tttcttaatt ataaatatca ttatcatagt    120840
     gtatggttaa aagaatatat tattgtatta aataagtgct aaatactaaa tggtcatgag    120900
     gaaagaaaaa tatgcagagg ggtgtaaaag taggatgtaa tccaactata gtttgctttc    120960
     aatgtttttg accaattcct tgtatttctc agtagaatag gactttggcc tttcaatgga    121020
     agcaccgatg gccctatcag tgatcaattg agcaagaata ccaaatgccc ttgaaacgcc    121080
     aaataaaacg gtatagaaag aagattcttt tagtccataa tattgtaata agacaccaga    121140
     gtgagcatct acatttggcc atggattttt ggttttacca tgttcagtca atacgccagg    121200
     tgctacctcg tatattgatg aaactaactt gaataattca taatctggaa aatggtccat    121260
     ggcaaactta cgctgagcca tataacgagg atcagttttc cttagcacag catgaccata    121320
     accgggaatg actcttcctg agtttagagt atcccataaa tatttttcga tcgtatcttt    121380
     agagtagtca tcatttacct cttctttaag tgcaaataac cattctagta cttcttgatt    121440
     agcacgccca tgaagtgggc cagccaaccc gttcaaacct gatgcaaggg acagataagg    121500
     tgatgatagt gctgagccca caagatggga tgtatgtgca gatacattac caccttcgtg    121560
     atccgaatga atggttaaat aaagtctcat caagtccacg aaatcttcat ccttagaacc    121620
     aatcaagttg accagatttt tagcataatc ggcatttggg tccacttcac ccattttgcc    121680
     atctttgaat acattacgat aaattttagc tgcaataact ggcaatttac ccagcaagtc    121740
     tagtgaatct tcaaaagtat aactccaata atcttgcttg gaaattcctt gagcataagc    121800
     cttagcaaac tttgactcgc tttccaaggc agttacagca atagagaatt gagccattgg    121860
     gtgtaagtcc tttggtaaat tatccaaaag ttgaacgaca tgactaggta gttccgatct    121920
     tgacattaga tcagctgata agttttcaac ttgcgcttga gttggaacct cgccagttag    121980
     caataaccaa aagagagctt ctggtagtgg ttgtgagctt ccttttgcct tgggcaggtc    122040
     cttttgaatg tcggcgatcg tacgacctct gaaacgaata ccgtcttctg ggtccaaaac    122100
     ggaaccttcc catacgctcc ctggaatacc tctcatacca ccatatacct gttctaatag    122160
     aacatcgcta attttagttt tgccatgctc tttaacgaat tgccttacat cttgagcatg    122220
     gatggggtag atttcgctaa atctctcttt tagagtcttt tcttggcttg aatttgattg    122280
     taaatatgat gcaacatttc tgtttgaatt tagataagga actgtcattt ttcttgttac    122340
     tagtattatt aaaacaaaaa gttttgagaa cctgttatga tatgtgttga tattgttccc    122400
     tgaaacttaa taatgaggaa cgaacaccat atctaaagaa ccaagtttta atagtcttat    122460
     atacgctcaa cgtcgagaat aatgggccct tttgagagca tgactatctt tagattaacg    122520
     tcaccaattt catacgaatg taacgctcaa aaggtaattg cgcttaccat tgttattgtt    122580
     tttccgctgt gcctcccatt gctgacgccc tgatagacgt ctagctacgg aaaaggtcac    122640
     actttttttc tgcaagaaaa aataggtcgt gacctcttcg cccctagtcg atgaccaccg    122700
     gataaatgcg tcgaatgtgc gcgctattag tttgcgctct tttgagatac cgccaagcca    122760
     ttgattgaat gacccaagga cggatttgtt caacactcca aagcggctta tgttgtggca    122820
     acaactctgg ggaaagtcag cgcaatgttt tcccctaagg attcgcgcga gccgtgtgta    122880
     acaaagttcc gccggtatag catatctaaa ccacagaagg acgcttatac ggccgtcttc    122940
     cacagtaatt agaaggacat tagtcggagt gtaaataaga cggttgcata cgcgtatgaa    123000
     catgggccat tcattttacg gaaatggcaa cacattttct tgtttttaat gtaaatagta    123060
     cggagttcct ttttggtgcg ctgaatgtat gccgtagttt ggtttcttgc caggcgtgag    123120
     aagagaggtc acacatgctg ttggggttca tgattttcag ccttcgctct gctaagtaaa    123180
     aggtccattg atccgaagcg cttcctccaa tatcgcagtg ataaacggtc atgtaagcct    123240
     acagtcttta aactgtagat gatttaatgg attatctcat acattgaata tcacacttca    123300
     gcagttcaag ttttcattaa cattggtctt ctccagctta ctctgtaaag tccgctgcag    123360
     ttttctagaa atcataatct gtacctccat tcagccatct gaggaacctc cgaaataacg    123420
     agtaaatgtt caaacatgcc atgcgccttg gtttattgta cgagttttag catattgcaa    123480
     aaaaaaactg ctcctgagta cacttgtttt acgtcggaaa gataaatgcc gtaccatttc    123540
     tgccagtagc gacaccacac attgtaaaaa caatgtgggg cgagccggga ctcgaacccg    123600
     ggacctcccg caccctaagc gagaatcata cctctagacc acacgccctc ctttgaaaaa    123660
     tcccggcaga acagcgcctg aagtctggga tacagcccta ttttccctgc catcgtcatt    123720
     gacctttttc ttaacgacca gattaacagc cagttattga aagtttgcga acgtgaagta    123780
     aaactgcaaa atggtcgttt taagtcaaaa gtaaccctgc gtcacacatg agaaacatta    123840
     tcgctaagtt gttgttacta cttcttgtaa ttaacttact gtcgcattcc aaatggactg    123900
     cgaaacagac acgaaacaat tacgaaagtg acgacagagt aaatattgtc attaaagaga    123960
     atgatgacct ccgggtaaac tgtgagaata agtctagacc attcgttaaa cttcatcttt    124020
     aattgagaag catagtaaaa aataattaac aagttaacac aactatcttg acccatgcta    124080
     ccaaggacat aagtaatatc ctccaccact tttactcaaa gtatatctca ttctgagaaa    124140
     tgggtgaatg ttgagataat tgttgggatt ccattgttga taaaggctat aatattaggt    124200
     atacagaata tactagaagt tctcctcgag ggtctaggaa tccccataat ggaatctata    124260
     tttctatata ccaatattac gattattcct cattccgttt tatatgtttc attatcctat    124320
     tacattatca atccttacac ttcagcttcc tctaacttcg atgacagctt ctcataactt    124380
     atgtcatcat cttaacaccg tatatgataa tatattgata atataactat tagttgatag    124440
     acgatagtgg atttttattc caacacattc gagctagtat aaaattgtga ggaattatcg    124500
     ggcatcttgt ttattaggta cgcaaattgt aataattgcc aagttgtgct ttttagttga    124560
     gaagtattcc gtcctcatga aatggctaat ataagtatgg atttcataaa tattatccaa    124620
     agtaattata cacacttgtt ttttgctatg tcttgggttt aagagaaaat gctacataga    124680
     ccgtaagaac gtcttcaaga atgcaaggat gctgcaagcg aagttgttcc cgttatgaag    124740
     cagaaagggc acatcaacat ggttcaaaga tttaaatttc ggcacttgtt cttgttcact    124800
     atatgtttta agattcttat cgtgcaagta ttcaattata tcctctaagt gaccgaacaa    124860
     tcaacacatc aagatttttg tagttttgaa gttccacaac ctacaggtta gtgctatttg    124920
     gtctaattta tacatgggaa ctatgtgaaa cagtaatgtt agcacaatgg acctctcaaa    124980
     gcctaagaaa attttgctgg ggacaaaaag tggttcttga tggtaaagaa gtagtttagc    125040
     ttcataataa tttctttgta aaatttttct cgtagcacac taagctttca gaaatcaaat    125100
     aaggcagagg aagtggtttt gtcgtattca atgactaatt gtaagactcg agtataactt    125160
     atgcagtttc caagaagtaa gcaaacagtt tctctcaacc tttggtgaca cactatgcgc    125220
     atgcaagtcg taatgcttct ctatttatgt gtgggtttat taaaatagtt agaattatct    125280
     aggtttgtgg gaatttggcc atgaatattg aatagtaaca agaacaaagc gtgaaaatgt    125340
     tgaatataat gaaagctgaa gacatcaaat catgttctcc aaatctttct gtctcgtata    125400
     ttttctttga tatttgtttt atgcggaaat tgcagtggaa acaatcgcga aacattcgag    125460
     aaagaaacta ggtagctaca aaagtatgga aaaaagggta ataagcattc cttttttttt    125520
     agccgcaaag cctgcttaac catacatgaa gcactttaac atatagatgc tgctcttcac    125580
     tgttacatta tatacagaaa aaagtgctcg caataagaaa caaaccttca gaaaaagaag    125640
     cttatcttga gcacaagtca ttcacagcaa aatttctttt ttcagttgct acatgttaat    125700
     tatggagtcc tgagagtaag taactagcca ttagaattaa tttccttccc ttaaaaatga    125760
     tagggaatgc acgacaatac gttaatgtgc acccaacttg caccacagca tattctatcc    125820
     tttagtttgt acaatattat tagctgtgag aaagcccctt cgtgtggcac aaatttatta    125880
     atctctgtca aaatacttct acttgtttat actgtataaa cgattaagtt ccattatgaa    125940
     ttgtgaattt agaatcggtt tggtacatcg ctcagtataa gtgctaaata aaattatcaa    126000
     gatttatatt tcatggtata tcggcgtcag gatattgctt tctccaatat tcctgttgtg    126060
     cttgtttctc aacttctact gctttaacaa agtatgcttc gaatattggg tcagaactga    126120
     aactaaagca ttttattacc tcatttgaag cctcatttgc tggtgcatct atctgcgtac    126180
     ttgtggcgtc ctttaccgat gaatttacat tcacacctgg gggtttttct ttcacaagaa    126240
     atctgaagaa tttgtagcat ctttcactac tataaaagta atagcgagta ctccataaac    126300
     cattatcaag taaatattga ttcatattgt ctgtgattgc tctccattct tttcccttta    126360
     ccgctggcct gtgggtgata acttccagca aaagcttaat tctgaaaccc tcatccgaga    126420
     tatacacatt aaacggaatc aacgtagaca aaaacaaaat agaagtgacg aaaattgaaa    126480
     aaccaaaaac gacatcacaa gctttaacat tatgaaagat cacaactatt aaaattgaaa    126540
     ctgaaagtgc caagaaggaa aatatcatcg gtttgtaatg agccatctcg tacagcaagt    126600
     aggtcatata tgatttaaag gtgtcttcag gtaaagtgat attttctgcg gatgataaca    126660
     cattttgttc ccctaatgta tccaatttga catcgtcatt attactgttg ttgtctaaat    126720
     gaggctgcat gcagatacgg agttttgttt cttgtcttga tatggtatag acaaccgact    126780
     ggtgtatata aacagaacac agacttacat tttcaggttc gaagttttat tgaagttcat    126840
     aaactctttt taaattattt tgtaaacttg agctattcaa gcagtattct tatttaacct    126900
     aagcatagcc ccggatacaa ggcgtataat acccaactaa cttaaaatga gagccactta    126960
     ctgaacacct tggaaggtca ttgtttggtt gaaaggaata ttattaacta agccttagaa    127020
     caaggcgtca cctaaatgat aatggctttt cttctgggcg cggtcggggc ttcgactcat    127080
     ttgatactag gttaattacc cttttacgca tacctaaata tttgtaactt tagatctgtc    127140
     cactaaaagc gtttcgatga cttagttgtg ctactaatag taaactcttt gtgcaggcaa    127200
     attatatcat cgctggctag actttttgtc aaaagttctg tttatacagt gggcagctag    127260
     agtgcttaat aacaaagata ttgtccttta gacttacaca agagcagaag caaagataag    127320
     cactgtttgt tctgcttcca tcgtttttgc tgaaaatttt gcatgcatat ccaaccaata    127380
     tttaacacct ggattatctc ggttcaaaga ctacaataaa cgccccaata attgtgatgc    127440
     ttttttcaat ccagcccgca caaatgaata ccgctgctat tggatgccat cttcagatgt    127500
     acgtccaaac tgtggttggt atagttttta gaacctcgtg gtgaggagtg ttccattctt    127560
     tcaaaggcaa tgagaaaaaa aaacagttgc gatattagtc aactgttttg catggtttct    127620
     ttgacgcagt tgtaaaatca tactcgaagg gtagttggaa aattttcaac atatattagt    127680
     aatacttttt ctgtaaaagt gacacaagat aaaatgactc catggccaag ttggttaagg    127740
     cgtgcgactg ttaatcgcaa gatcgtgagt tcaaccctca ctggggtcgt taatttttct    127800
     tttctttttt tttttttatc tccgacggag aaaaaatttt ttctcaaccc ccggcatggc    127860
     gaatggaaaa atcacctggc acgtcatttc atcaaatcaa catcggcctc cccgtgctaa    127920
     tatgttaaca ggccgagctc ttgccatctc acgcattttc cgctatacaa atagtatata    127980
     taatattaca gcttttaaag agggaagagg aaacggagaa gaaaatatac tactttatag    128040
     agatattcgg caattttttt tagcaaaagt ttattaaacc ctaatataga cctttacttg    128100
     gagtttcgat tttaagaatt ttttatcatt tttttttttt gacgatttcc tgtcggtttc    128160
     gttataacct gttgtgttgt tgttgttgtt gttattgctg ggttgttgtt attcacttta    128220
     acattatcga ataaaatttg gactttcaaa gtcctgttca ataagttgta ctaagccttt    128280
     aagcgttttt aagttacaaa taaaaactgg aaagcttaag gtagctttct aatattaggc    128340
     tctcaacctt tttttactct ccatttaccg ctagatatta actagtagta agtattgtga    128400
     ctactattcc ctgtaatcaa aaaaaaagta atcagatttt attttatttc gacattaccc    128460
     ctcaaatata tgactggtat gaatgataat aatgccgcta ttcctcagca aactccaagg    128520
     aaacatgcgc tatcttctaa agttatgcaa ctttttagaa gcggttcaag atcatctagg    128580
     cagggaaagg cctcatcgaa tatccagcca ccttctaata taaacacaaa cgttccatcg    128640
     gcgtctaaat cagccaaatt tggtttacat accccaacca ctgctactcc tagggtagtt    128700
     tctaatcctt ctaatactgc aggtgtgagt aaaccgggca tgtatatgcc cgaatattac    128760
     cagtcggcat caccatcgca ctctagttca tccgcatcat taaacaacca tattgatatt    128820
     aacacctcta agtcatcatc agctgcttct ttaacttcgt cagtatcagc tttatcctta    128880
     tcacccacat cagccataaa tattagctcc aaaagtttga gcccaaagtt ctctcatcat    128940
     agtaacagca atactgctat tacacccgcg cctactccca ctgcttcaaa tattaataat    129000
     gtaaataaga taaccaatac aagtgcacct atttgtggga ggtttcttgt gcataaagat    129060
     ggtacccatg aacatcactt aaaaaatgct aagagacaag aaaagctaag cacaatgatt    129120
     aaaaacatgg ttggtgcgag caaattacgt ggtgaggcaa aatctgctgt ccctgatata    129180
     ataatggatc caaagacgac tttaaaatcc aacaagaatc ctcctactct ttttgcaggc    129240
     ttcatgaagc aggtcgtgga tatggatgat aaatatccag aaggcgctcc cacaagtggc    129300
     gctttaaatt gtcctgaaag ggatatatac aggtcagatc aaaaagattc caaaaataat    129360
     acgcataata tcactactac taaaaaagat aggcaatgtt ttgccgaaaa gtatggtcgc    129420
     tgtcaagaag tccttggtaa aggtgctttt ggtgtagtaa gaatatgtca aaagaaaaat    129480
     gtttcttctc aagatggtaa taaaagtgaa aagctttatg cagtgaaaga gttcaagcgt    129540
     agaacatccg aatcagcaga aaagtattct aagaggttga cttctgaatt ttgcatttct    129600
     tcttcattac accatacaaa tattgttact acactagatc ttttccaaga tgccaaaggc    129660
     gagtactgtg aagtaatgga atattgtgca ggtggcgatc tattcacttt ggtcgttgcc    129720
     gccggaaaat tagaatatat ggaagcagat tgtttcttca agcagcttat tagaggtgtt    129780
     gtttatatgc atgaaatggg tgtttgtcat agagatttga agcctgagaa cttactgctt    129840
     acgcacgatg gtgtgctaaa aattacagac tttggtaaca gcgaatgttt caagatggca    129900
     tgggaaaaaa atattcacct tagtggaggc gtttgcggtt catcgccgta catcgcccca    129960
     gaggaatata tcaaagaaga gtttgatcca agacccgtag atatatgggc atgtggtgtc    130020
     atttatatgg caatgagaac tggtagacaa ttgtggagtt ctgctgaaaa agacgatcca    130080
     ttttatatga attatttaaa aggacgtaag gaaaagggag gctatgagcc aatcgaaagt    130140
     ttaaaaagag ccaggtgtag gaatgttata tattcgatgt tagatcccgt tccgtacaga    130200
     agaattaacg ggaaacaaat tttgaacagt gaatggggaa gggagataaa atgctgccat    130260
     aatgggcgcg cattgaaata aacgagtact tcactttcaa atatcacgat attttggaac    130320
     aattcggtat tttttactta atctagtaca ctaaggaatg ctttgttatc cggcattcgt    130380
     atcttattcc tcgcttctat tgttctactt ttatatcccg tttggctgat tacggatcac    130440
     gttcaaattg gtaaatccca ttaattaaaa aagaattgta accttattta aaaaaaaaaa    130500
     tagtacataa caataaaaaa aaaaaagata ataattttga atttattgct agacattctt    130560
     acgtttattg tgttcatgtt aacaaaaaca catgcccgcg gttattatcg ctttttaatt    130620
     gctttcttaa aaagagtcgg ttggtcagat agagcagata gtaaattata gtgctattta    130680
     ggtctgttaa tttaaatgaa agaaacataa atgaccgtaa aaaactaaag gcaaaagcat    130740
     taatttattt tatcccgagc gcacaaatat ctaggcttgt catttgtcct aatagttctt    130800
     cgattttagt gtctaataac ccattggcat agtcgtctct tgattgttgg tccaaatatt    130860
     gttgaatctg cgctaaacga gtgtaaccat cagtacagaa ccttagctga atcttgatta    130920
     aagcttcaaa acttgggtca aagtaaggta ctcttaatga aactaactgt ggtagttcag    130980
     ttttcaattg gttattaaga ttttcgaaaa tatctttagc taagctcaat tctttttcag    131040
     cccttggcag tttagaggca tctttagcag gtttgtccac taatctacga acttttgcct    131100
     tcgcagcatc gaagtcttgt ttcttatggt ctctcttttt tatggcctcc tcaatttctt    131160
     tgaaatacgt cgaaaacttt gttattggat ctagtacggt ttctcttaag ggcccgtcta    131220
     attgcttaac agtttcgcta tcaaaatctt gaacacattg caaataatag ttaccaacgt    131280
     tgtaaccacc accagcaaca tattttgaat cgtcatagag gttagagatg acctcggcaa    131340
     tggtagtctg tgatgctgtc acagctctca atgagtccaa gaaacctttg gcttcctttt    131400
     gtaatgcctc acctgctctt tgaagaactt tataacgacg ttcttccatg tcatactctt    131460
     tatcaatggt cttgtcgaca ttcttaatta tcacactgtg accagctctg ttgatagctt    131520
     tcttaaaacc ttcccaactc atcttgtatc agctttcttc tggcttctta taataggatt    131580
     tgtatagttt tctatatcac agcgtttcct tttcttctct cacgtctgcc tgttattaaa    131640
     tttgttttcc ctttctttta attcggattc tcataattgt tcaaaatccg cgcatttgga    131700
     tcgtccagcc cctgcagcgc ccagttcagc caacaaaaat tcatagggac gtaaaggaaa    131760
     cgtttcatgt ctgttacaat gaaaaagaca agtcgaatca cattatgaat ggcaaacgat    131820
     agacctttcg ttgcctttca attacatgat attcgtggca acatcttctc cgctaaccta    131880
     aaagttttat cagaaacata tatcttattt tttctgaagt aaaatcaaag tgcagggaag    131940
     acaagtaaag gagtcagcaa aaaagtgaag taaacttata tgttaactgt ttataaccgt    132000
     accttgctta catcatctat attttcgtaa tcatttttgt acattgttta tatcttgttt    132060
     tgaagtttta gctttgaaaa acatttaatt gcgaagtaac ataatgttat taatagtgta    132120
     cgactgaaac agccattcta tttaaacata taaaagtacg attagttggt gtggttatat    132180
     aagtcataaa ataattatca tattaaaaaa ttgaaaaata aaaaactact cttttttatt    132240
     tcaatagttc tcgttattag taggtcgtgc tcttaaaaga ttaccctttc agtagatggt    132300
     aatgggaatg gacgagccag tacatatgaa ttctgctttg tagcaacacc tgcatatgcg    132360
     ttgtaccaag caatgaaagc aacaacaact cccaggacac caccagctct tgtgacacca    132420
     agtctattag caaagtgacc aatagacaac agtaggaaag ttaatgctag taagaagaac    132480
     aacaaaaaga acataacagt ggatttcatg gtacaaacgg ttaaaccaaa cgtaaagatg    132540
     gcccacccca acaaataaaa tcctaaagca ttattcaaat cagattcatt gtcttcgtaa    132600
     gcttccaaga taccaaacca aggaatgtaa attgcagcga aactcaacca aaacccaccg    132660
     taagaacata atgcggtacc accaaaagta ttttccaaag ctatctccca aataccagca    132720
     atcaattgca ccaaaccacc ataaaacata gcacaaccga cgacaacatt aggaacagtg    132780
     atcccttgcg ctctcgcatt gaacatggac agcacaaatg tcgtcaacgc gaaggctgaa    132840
     agacctaagg gcgcaggatt agcaaatttg tgcactggag caggagctaa ccctggattc    132900
     aaggtaccac caaaggcttg gtataagtcg ctcttcaaaa acttttgacg cccaatatag    132960
     atatattcat tgttatcacc tccagtgtaa atcttgccca acgaatcatg agatggacgt    133020
     tcatcttctg caacgccatt aacgtcgtta tcatgggaac tatagtatcc tgctggtgca    133080
     ttctccaaat ctgtgtttcc gctcgtttgt tccttgtcag acatattatt tgtttgtata    133140
     tgagttgttt tgtggttgtt tagttatatc tgtgttagct gtcgactatt tgcctttttc    133200
     ttataaacag atgctagtag tttctgttgt attgttattg ctattggacg atatataaaa    133260
     tgaacctata gcaagatctc agggaaatac gatccaacca aggtgcttta tatacagctt    133320
     ggtgtctctg acaggttgga gtacagagga gaaggcgcca tagccgccca acccgcgata    133380
     acgaaaaaaa gctgtaagaa aatgcagtct tccccaacgt ttgttacccc aacaataccg    133440
     aaatagccgc ccaaccgcaa atctggcaaa aaatcttttc gtatctcgct gcagatgacc    133500
     ttccaacccg cccctttttg tagtcacgcc tttaagggcc cttgtttggc ttgctcacat    133560
     ggggctacac gtaaaaaccg tagcttggag aaccactcag ccgctcgcct attccacgga    133620
     gctccggatc aacgggcagt ggaccctctc gaaaataagg aaagttgcgg ggccaaaaat    133680
     tattatttct tatgtaaaag aagagactat atacgacgcc tatctacttt tgttccacaa    133740
     ctatccactt aagggctaga taccccatta ttaaaaacac cacattaaac agagccagga    133800
     tcttgatgtc aaatacaagg ttttggacaa caaatccaaa tgtgctcaag atagtagcgc    133860
     ctggaacttc aatatttaag ccgtactttc tctctttcag catcaatgtt ttgacctcat    133920
     tgatcaataa agattcgtag gcgtagtaaa acacagagaa gtttttcagg tacttgaagg    133980
     ccacgtttgt aatattctta gtattgataa atagtccgct aaacagtagt gagcccaaaa    134040
     gcaccagcac gcttaatatt atggagttat tcaagtcttc aaaaattatg ccgatggtta    134100
     ggatttccaa cgatatccca aggttaaaca gtataaggat tccaatacat ttaaaaaaag    134160
     cattgtcttt catgtttaaa ccagtcattg ggtaaacaat caatgacaag agtataggtg    134220
     gtacaacacg tagcgggacc acttcgctca ttatcttact aatgtagtat gcaagtggcg    134280
     agtaatagtt attggatctt tcttttatga aaatgatcct ttccagagcg aacgagctga    134340
     gacctgtgaa tgtaacaaaa ccgaagtacg ttagtataaa gaagaacagc cccattctgt    134400
     tctgaaaacc gctgatatca ttggagacgt tgtaatatag tgttcccaag aataaactca    134460
     ataggatcgt cagtaaataa ttacccaata atagtttagg gtttctgtac atgtttttaa    134520
     aacttcttga attcaatatc gataactgtt gcagaaaacc agcagattgt tgacctgtgg    134580
     gtaaatctcc attcaaaacg ttactttcct catcaccttc gcttaaaact tcctcgatct    134640
     cctgtgaaag ctctgcataa tagacgctat ctttatattt atcgtgtagt agtttggtat    134700
     ttaagtcaat ctcagtagca cctcgccttc catctgttcc ctctacatct tcttcatctc    134760
     tgagtaaaga tctgatctca tctctatgag ctgcaagatg agcccactct ctctgtgttg    134820
     taccatcact gctagtaaat gttgtttggt gtatcgtatt atcaatatcg ttagtatccg    134880
     taccagcttc taaatcggaa atgtttctga ttcttctcct tttcccctga ggaccggctt    134940
     caaaagtaat atcaatcaaa taatcagcaa tattatagtt gtccggacag atatatccct    135000
     catttctcaa aaattctgac acttttttgg catttccgga atagaccatc tcacctttac    135060
     ttaacaggac caatttatcg aataaataaa atatatttga tcttggctga tgaatagata    135120
     gcaccaatgt cctgttatag tcgctggata accttaccaa acattcaata acattattgg    135180
     cattactagc atctaaacca gatgtaggtt catccaaaaa taaaaccaat ggagatgtca    135240
     ctaattcaca tgcaatggaa actcggcgtt tttcacctcc actaatacca cgatcaaatt    135300
     cattaccaat aatacgatct ttgatatcaa taattcttag ttcttccaac accttataaa    135360
     ctcttgcctt cttggcctcg aatgacaatg cttttggcaa tcttaacagc gcactattta    135420
     atacggtttc aaaaacagtc aaagtgggca gcaaaaagtc atcttgatcg acgaacccga    135480
     ttattttcga gaaagattta cggtccatac taataccgtt aacttttatg gaacccgaaa    135540
     cgtgacctgt tttccgtttc attgctagga tatctaataa agtagtttta cccgcaccag    135600
     atccacccat gatagctaat atttggccgg gcttcacgat accacttatt tcattcagca    135660
     cagtttcttc aacaccatct gaatttatcg aggggacact ataagtgata ttttcaaaac    135720
     ttaatgtcgc cagtgtgtca tcttcatttt gtaagaaatt attcaccgca tcttcatctg    135780
     gcaaacgaat gggagacttt gaggaaccca atccatttct gaataacgga gatttagaaa    135840
     tgtaaaaggt agcaaatgta aaaagtgcca ggaccatcac agcagtcaat gccaacacca    135900
     atttcccttg ccatgacact gttggatctt ttgaaggaga tttgtaacct ggaatctcac    135960
     tataatgaac acattcaccg gattcacact tcaaagtaat ataagggtca ccaaacacgg    136020
     tcaatatcaa atcattcata gaaggctcac tgaatttaca ttgccttgtt tctaaatcac    136080
     agctgaaatc tcctggccct tttattgtct ctgtcaggaa atccgagata tctatagacc    136140
     ccttagcacc acacaacaca gtgtcgggaa cgcatttgca ttgaacgtca ttacacttat    136200
     aatgggaggt attctgttcc aagtcgtatt caaaggcaca atcacttaag ccacaataga    136260
     agctttctaa ctgatctatc caaaactgaa aattacattc ttgattaggt ttatcacagg    136320
     caaatgtaat ttgtggtatt ttgccgttca aaatctgtag aattttctca ttggtcacat    136380
     tacaacctga aaatacttta tctacaatca taccattctt ataacatgtc cccttaatac    136440
     taggatcagg catgaacgca tcacagacaa aatcttcttg acaaacgtca caattgatcc    136500
     ctccccatcc gttatcacaa tgacaggtgt cattttgtgc tcttatggga cgatccttat    136560
     taccgctttc atccggtgat agaccgccac agaggggcag agagcaatca tcacctgcaa    136620
     acccttctat acactcacat ctaccagtgt acgaattgca ttcagaaaac tgtttgcatt    136680
     caaaaatagg tagcatacaa ttaaaacatg gcgggcatgt atcattgccc ttatcttgtg    136740
     cagttagacg cgaatttttc gaagaagtac cttcaaagaa tggggtctta tcttgttttg    136800
     caagtaccac tgagcaggat aataatagaa atgataatat actatagtag agataacgtc    136860
     gatgacttcc catactgtaa ttgcttttag ttgtgtattt ttagtgtgca agtttctgta    136920
     aatcgattaa tttttttttc tttcctcttt ttattaacct taatttttat tttagattcc    136980
     tgacttcaac tcaagacgca cagatattat aacatctgca taataggcat ttgcaagaat    137040
     tactcgtgag taaggaaaga gtgaggaact atcgcatacc tgcatttaaa gatgccgatt    137100
     tgggcgcgaa tcctttattt tggcttcacc ctcatactat tatcagggcc agaaaaagga    137160
     agtgtttccc tccttcttga attgatgtta ccctcataaa gcacgtggcc tcttatcgag    137220
     aaagaaatta ccgtcgctcg tgatttgttt gcaaaaagaa caaaactgaa aaaacccaga    137280
     cacgctcgac ttcctgtctt cctattgatt gcagcttcca atttcgtcac acaacaaggt    137340
     cctagcgacg gctcacaggt tttgtaacaa gcaatcgaag gttctggaat ggcgggaaag    137400
     ggtttagtac cacatgctat gatgcccact gtgatctcca gagcaaagtt cgttcgatcg    137460
     tactgttact ctctctcttt caaacagaat tgtccgaatc gtgtgacaac aacagcctgt    137520
     tctcacacac tcttttcttc taaccaaggg ggtggtttag tttagtagaa cctcgtgaaa    137580
     cttacattta catatatata aacttgcata aattggtcaa tgcaagaaat acatatttgg    137640
     tcttttctaa ttcgtagttt ttcaagttct tagatgcttt ctttttctct tttttacaga    137700
     tcatcaagga agtaattatc tactttttac aacaaatata aaacaatgtc tttatcttca    137760
     aagttgtctg tccaagattt ggacttgaag gacaagcgtg tcttcatcag agttgacttc    137820
     aacgtcccat tggacggtaa gaagatcact tctaaccaaa gaattgttgc tgctttgcca    137880
     accatcaagt acgttttgga acaccaccca agatacgttg tcttggcttc tcacttgggt    137940
     agaccaaacg gtgaaagaaa cgaaaaatac tctttggctc cagttgctaa ggaattgcaa    138000
     tcattgttgg gtaaggatgt caccttcttg aacgactgtg tcggtccaga agttgaagcc    138060
     gctgtcaagg cttctgcccc aggttccgtt attttgttgg aaaacttgcg ttaccacatc    138120
     gaagaagaag gttccagaaa ggtcgatggt caaaaggtca aggcttccaa ggaagatgtt    138180
     caaaagttca gacacgaatt gagctctttg gctgatgttt acatcaacga tgccttcggt    138240
     accgctcaca gagctcactc ttctatggtc ggtttcgact tgccacaacg tgctgccggt    138300
     ttcttgttgg aaaaggaatt gaagtacttc ggtaaggctt tggagaaccc aaccagacca    138360
     ttcttggcca tcttaggtgg tgccaaggtt gctgacaaga ttcaattgat tgacaacttg    138420
     ttggacaagg tcgactctat catcattggt ggtggtatgg ctttcacctt caagaaggtt    138480
     ttggaaaaca ctgaaatcgg tgactccatc ttcgacaagg ctggtgctga aatcgttcca    138540
     aagttgatgg aaaaggccaa ggccaagggt gtcgaagtcg tcttgccagt cgacttcatc    138600
     attgctgatg ctttctctgc tgatgccaac accaagactg tcactgacaa ggaaggtatt    138660
     ccagctggct ggcaagggtt ggacaatggt ccagaatcta gaaagttgtt tgctgctact    138720
     gttgcaaagg ctaagaccat tgtctggaac ggtccaccag gtgttttcga attcgaaaag    138780
     ttcgctgctg gtactaaggc tttgttagac gaagttgtca agagctctgc tgctggtaac    138840
     accgtcatca ttggtggtgg tgacactgcc actgtcgcta agaagtacgg tgtcactgac    138900
     aagatctccc atgtctctac tggtggtggt gcttctttgg aattattgga aggtaaggaa    138960
     ttgccaggtg ttgctttctt atccgaaaag aaataaattg aattgaattg aaatcgatag    139020
     atcaattttt ttcttttctc tttccccatc ctttacgcta aaataatagt ttattttatt    139080
     ttttgaatat tttttattta tatacgtata tatagactat tatttatctt ttaatgatta    139140
     ttaagatttt tattaaaaaa aaattcgctc ctcttttaat gcctttatgc agtttttttt    139200
     tcccattcga tatttctatg ttcgggttca gcgtatttta agtttaataa ctcgaaaatt    139260
     ctgcgttcgt taaagctttc gagaaggata ttatttcgaa ataaaccgtg ttgtgtaagc    139320
     ttgaagcctt tttgcgctgc caatattctt atccatctat tgtactcttt agatccagta    139380
     tagtgtattc ttcctgctcc aagctcatcc cacttgcaac aaaaaaagtc taatcttctg    139440
     caataatttc catccttggc attcagagac atatattggt caatcggttt taattttgtt    139500
     tcttcttctt cttcttcttc aattaacaat gtgccttcat catttttcat ttctttcagt    139560
     tcttctaatt ctcttggaga caatttgact cccatgaaaa atttcttgat tatctcagaa    139620
     gaataccacc tctttctttc tccataccca acaatcttcg ctgtacgaaa tctctccact    139680
     attcttttta agaatagctt ttccaagttt ggcgttagct gtaaaaaaca atggatatag    139740
     ccatccttgt acaacttaat acaaagcgtt tccatgattt ttgccaactc ggtcgtgtca    139800
     ttacaaaacg gcttgaaaaa taaaagatca atgtcaccac acttggaata gcccctatta    139860
     taacttccct gtaattcgac ttggcattca ggatcaatgc cacgcagcgc tttttgaacc    139920
     ttctttaaat gtgtgaaaca ttcattccga gacatcttgc ataaccaatc gtcgtaatat    139980
     gaccaaccaa ataaaattgt ccaatctgat acaaactcct ctgggtcctt cttagctgca    140040
     acacaaaagc tttcaaaatt tagaagattc cagcgtttag caatttccga cccaatgccg    140100
     taacaatttt tgaagtattt caacttgtct tctaatccca ctgaatcatt taaacctggt    140160
     aaaactcccg tatctaatat aacttgtatt tttttggcaa tactaggccc gatattcctt    140220
     aatttagtat gtgcttcttc accggaacga acattgaaat cgcaattttc catcgactgt    140280
     ttagccagtc tataacttct tgcacgaaat ttctcacctt cgatctcata tttttttgtt    140340
     aaccttttca acgctccgat aatcaattca ttgtttttgt acttcgtttt gtcagtaaca    140400
     agggaagctc ttcctttatc cccctgtaag agtcgcttaa gaggttttga agcttgtatc    140460
     atatctttat tgttgctgtc atcattcctt tcactttcta cgtcagttga aatctcactc    140520
     tctttatcag tagaactttg tccgtcatca gcgttatctg atataacgat aatggatggt    140580
     tgaaatttaa tcaaatcatc tttttgaaac gcaaatttat cattctggac ccactttgtg    140640
     atgcaactgg ttttcacaca ttgaatgcct gactgttcaa tcttaccaag aaattcatcg    140700
     acatcattta agcctgcttc cctttggaaa atatctttct gagtcaaatg catatcagaa    140760
     tcaacaaagg agtcctcaat caaaatgacc acttccttac ggctagattg aagacaattt    140820
     tgaatacttg acacaattgt ggcgcccttt ttctccaata tactcttaaa gaacttattg    140880
     gaagatgtgt taggattagg taaaaaggcg aaaaatttac cctttagaga catgtgcgat    140940
     ttgtctaaca ggtcgcatgt ttatccttta cttattatca ctgtgacata taagttcttt    141000
     gcaagccctt aaaattatta gccccatgta tttgaacatc tcaaagtaat tttagaccga    141060
     gaccgattac ggagatagaa gaatagtgca agtgaaatac tattttatct ttacttaaaa    141120
     aagaaaaaac aggaggaaaa ttagcggtat tccattatta ttagcactgc aacgtcctgg    141180
     ttatataaat ttgaatatac aggatttcat ccgtttctac atttttgtta cctgcatgat    141240
     caaatctttt aaagagtccc aggatttcac aaggtaggca cctttaccgc cttccttttc    141300
     acaaaactgt aaccacgctg gaccattatc agcttcaaaa ctcgagattt tatcctttgg    141360
     gataccaata atcttttcgg taatttttat gaatttggaa ggattttctt gcgggtttat    141420
     tagcagtaca ccattagtag atggatgtaa tatggacaac aagtcagtct cactatcccc    141480
     tatataccaa tagctgcaag aatttccttc tttattgcaa cctgagtcga tcttatctaa    141540
     tatttcaccc agtatcttga ccttatcaga gcctgtcaat aaccgacaat caaattcacc    141600
     attgtagctt tgagaacact tgtcactaac tttttttaga tcgttacaaa aaatatgact    141660
     atttttaagt cttctgtcac caatgacttc atgaataaac tcttttgacc aatttataga    141720
     taaaacgtaa aaatcacttt caaaattttt gacaactgaa gagcaaaacg ttttgaaacc    141780
     atctcttagt aaacaatctt cgtgattctg atctctggcg aacgttttca tttgatccaa    141840
     agaaatcgac ttaaaaatct gttgttttgt aatttcattt acactattta actcaacaac    141900
     cctgttatga ttttgatatt ttaattcgtc cgcaaacaac ttattgaagt tagactgcga    141960
     aattatcgta ggtacgcctg aagataacaa cggcagtgat ctcgttccat tgtatttgta    142020
     tttatggtat ccgtccatat atgtcttggt aaaatgaccc cactcaggtt tcaaccgcgg    142080
     gttcagtaga tacggtaatt tagcaatggt gcagattgtg tcaactcttg tgattgtttc    142140
     atcaaaatct gaaataataa tggttttcat atcctccact gttcgcttct ggttactgca    142200
     attgttaaat gcattggctc gattgtcaac attgctttgt gcgaagaaag gtcgctttta    142260
     aagaaaacga taagaactaa cctctaacta cataataata agaaaaaagt atacagataa    142320
     acaagctcag tagtaataca taaaataaaa agttttgcaa atcgattgtc cacacacttc    142380
     tatatcaatt ccaactaaga aaacgaagga accgactcaa accggtgtaa aagctaggct    142440
     ttcaatctct gctcctccaa acaaaactag tgcttgatat cacatccaat taaattacgt    142500
     aaataatttt agagtgacac catcgtacaa agagggcatt aagcttattt ttttaattct    142560
     tatgaaaaaa aaaatgtgaa agagagtaga aaattttcat aacgaatctc ttctattctt    142620
     atgtaccgtt ccgccaaatt tttcatgaaa aaatttggga aaaagaaaaa aaaaaaaaat    142680
     agtatataaa gtaaaaaaga tgcgcaagcc cggaatcgaa ccgggggccc aacgatggca    142740
     acgttggatt ttaccactaa accacttgcg ctagtaatct tgatacatga ttcgagaaaa    142800
     gcaacaatat tatgtatacg gaatatacta ggagttctct tcaaggatag aggaatcctc    142860
     aaaatggaat ccatatttct acatactaat attacgatta tcccttcttc tattttatat    142920
     gtttcattat cctattacat tatcaatcct tgcacttcag cttcctctaa cttcgatgac    142980
     agcttctcat aacttatgtc atcatcttaa caccgtatat gataatatat tgataatata    143040
     actattagtt gatagacgat agtggatttc tattccaaca agaacatcct tgaaaggtcg    143100
     actattaaca taagaataag agagagtgtg tggccgatgc tgttgctata gctcggtcgt    143160
     agtttaacac cacggcatta ttcagcttta aaacaattga attataaacc tgcttttctt    143220
     actacgaaaa gtgtttccct ttaataaatc tattgtacat actttacagt tgatagtacc    143280
     ttcaccataa aaatatgcaa acgcttttgt tattgggaac aggaatacca accgttctca    143340
     tggaaaatag caaagtgtaa aagaatttat tatcatcgag tgataaagaa tatcgccaga    143400
     tctttacgga tatatatcgc taaaaatatt tgtcgccaat aaaagatatg tctaacgctc    143460
     cctttgcagg tagtttttta ctggcatcgc ctttttactg caaattattg aaaattttcg    143520
     agcgagaaaa aggaacgaaa agagatgagc taaattcaaa tatcaaagta ctgtcataag    143580
     tgctttcttt atcgacaaat tacaagcaga agaaacattc acttcacaat taaatgtccg    143640
     aaaatcacgt tcctgcctgg aaaagaattg ctttgaagag acagactata agcagtggtg    143700
     acgaaagtaa agaaaaaggc caatccaatc taatagatga tgatccacta aatatcacta    143760
     cgcatttatc cactggtaat ttgacaaaga aagagaaaaa aagaatcatt aatggtgaga    143820
     gcaaatcctc taccaaaaaa gggaagcgtg tgtcgaaacc agggacgaag aagaaggaaa    143880
     aattgtcaaa ggatgaaaag aattcgaaaa aaaataaaat tcttaaagat caattacgtt    143940
     acctgataga atttttcagg acaaagtctg agagcaagtt tcccaccgga atcctagaat    144000
     tggaaagtgt aaaagaaaat tacggcgact ccctgatcaa agacgagcca tcagagtctg    144060
     gtgttgttga agtttggaaa ttttccaagc aaaagcaaaa ttggcttatt aagcattttt    144120
     tcaacttgga cgaaatcccc tcagtatata atgatctttt gcttttatat ttcagggact    144180
     tacaaggtaa atcaaaagaa gaactaatat caaaatgcaa aggaaaactg aagcaatgga    144240
     acgactatgt ggaagatcaa gaaacaaaaa taaaagcgtt aattgcagag gataaggcta    144300
     gcgaaccaat taatggtgaa gaaaaagaag aaggtgaaaa agacggtaat gccgaacaag    144360
     ggaagcaaaa agaggtacaa gacgagcaag aggaagtaca aatgccgaat aaagagcttg    144420
     ttcaaagaag tctgaaatta ctagaaattt ggaagaatga tgactcggag cagatagaac    144480
     ttaagaattt cttcgttgat gtttaacata gagttcaaca acgttgttca gttgtagtat    144540
     atattttact gtgaaatacg ctcaaaaagt agcgggataa atcgtttcag gaagtataat    144600
     ttcttacaaa actataacaa gatcgtctaa gtaacataca taaagaaatc acataaattt    144660
     ttaaaattcg aggtcaaaaa aatcaggtgg atacataact taccttaagt tatcaagatt    144720
     ttcagtacac acaatgtgat tacactgatt tataaaacca ccttacggcc tcttataagt    144780
     aataacgtgg ctcatcaaaa acatggtaga agtgacccct ctcaccttcg cctaaaaact    144840
     tatctggaaa tttcatgtcc tcatattccg gttcactcat atgaccgtat tcatacatag    144900
     aatccgagtg ctctactaac gcttgctcac tcaaaacttg gaacttacca acttgtagct    144960
     ccgtatcggt tatcgttcct cttgcaactc tagcatatcc tgttcttctc aagcccctat    145020
     acaagatata ctcacaccat ctatcatcgt cagaaggatc aatgtcgtgc attccggatg    145080
     tttcactaac gtacgtattg tagttgcctt cacctggatc aacaactaag taacttaata    145140
     aaatagctgg gcgagtcgta ttgcccatga gcttagccat gtagttactt tgcagtcttc    145200
     tatcctcttc atcctcttct tgtccactat ggaatacaaa gacgtcaacg agagtgtcat    145260
     tgtacgtttg aagtgtggca tgaatggctg gcgcaagttc cccaactgga gagggcaata    145320
     aatgatgcgt agaatttacg atagggaatt tagaaagaag aacacagccc caggtatgtt    145380
     tatttggacc tggtccgaaa tctgcataca tattcaaatc atgagctagt ttgctagtta    145440
     gatccctgtt ccccatggta attctttgtg tatctgtttc tagtagacct accacatcta    145500
     gttccatatc tttaataagg ttgatcattc tgtcttcaga tgcccacata tcattatcga    145560
     gaccaaagtg gatagtccaa ataccagctg taatcaactg agaatctgga tgataaggct    145620
     gaggaattcc tgtaggtcta atatcataca cgaacctagc tgttagtgat agcagggcca    145680
     cggcaaagaa gaaaacataa atgaagaatt ttttgcccat agtcaccagt tgaatgttaa    145740
     ggtttttgca tgttaaagca ccaataatga taaatgtgga agaaaaggca agaaccgtct    145800
     caatcttctc cctcagtacc cagcccattg gaacaaatgc gtatgcaacg acccaaacat    145860
     gggcaaggac aaagataata taaacggaga atgataggac ataaacccat atgttttgaa    145920
     cttggcctaa tgcagaaaaa tacgaaggaa ctaaccaaag catagcgata gcgtacaata    145980
     aaccaccgaa aatatattta ggccattgtg taatgcttct agctgaaagt acagcagtgg    146040
     atatgagaag caacaaacat ggaactaatg gcttgcccat aaacttcaca gaactcaaag    146100
     aagcaaataa catgaccgta caagttaagg cgccccaagg ccatggcaag ggaccgtgtg    146160
     attcattgta accttcccat gcccaataaa tagtagtaga agaatccgtc aataactgat    146220
     gaattccgaa taacaacgag ccaaaaccaa cagccaaaaa taatttgcca atcaacgaag    146280
     cagattttgc ttgagcattc cttttccctt cgaaattaat tgaattaaca taaggcgaca    146340
     gcatgccgaa taaaacagta agcacgagag ctgtcttatt atacccacca ttacgttcat    146400
     ctaaaatgac ccaagttgga ttgttggtat agaaccccat tttcaagatc acagatgcaa    146460
     caagacctaa cagccaagtt agagcaaaag agaaactagt ctccgcattt gtgatatatc    146520
     ttagattttg tacaaacgtt gcaacggtaa tggaagttcc cacagctaca gaaatcaacc    146580
     ttaattctgg catctgaaca atataggcac caatggcaat aatacctcct aaaagtacac    146640
     catattgcgt gaaggcttca gaaacgaacg gcagatataa gaaaatgggt cccaaataac    146700
     ccaatattgc agcttcataa cctgagattc ccatatacca tagcgggaaa tgccaaatac    146760
     tacataacag ggacgtaacg ttcgaccaga aaagaaaacc gttaaaaata tttgttagta    146820
     agtaaaaaaa agagtcaaac ctgaaatatg aaccagttgc gcttctagca acgggttttt    146880
     ccttttcaac cttcttttca ccacttttct gcaattctga acttttttct tctccataat    146940
     ttatgggact agagtctcta atttggaaaa aactggtatt accgggtttc tcattaaaag    147000
     cgagaacaat atctatcttt ttgaaatcag cgtaagcaaa tgcatcaaat gcaatatcta    147060
     aaagaatcag agaccattcg aaataagcat atatagaata tgccccagct ctctgttgga    147120
     cggagtgctg aatgtaccag taaatcatcg ggaacaatgt tccaaaaaaa attgtagcag    147180
     tcaacccttt gttcttcgaa gttaaaggac tagaatagcg ggtaatcatt atatcccatg    147240
     gtaacgttaa aacaatgtat gtgatcataa atatatcatg aatatcgtgg tcatctgtac    147300
     ttgtaatgta tacccaacca ccgcaagaga ctgtccggag tacaccgaca aggaagcata    147360
     ccttagattg gttcaagtag tagtgaccta gtagcagtaa aaatcttgga aaagcagtta    147420
     gagctattaa gatttggaaa atagaacgtt ccggatagcg gtccccgata gtggctgata    147480
     cactaggaaa ccactcatct ggatacgtat aatgtgcatt ggttacaatt ttatgaaaat    147540
     gtaatgaata accagtgacc aaagctgcaa agaaggcgga gaatgcacaa atagtatgag    147600
     ctatagggat gatcttccca ttgatgatca gcataactgg cggtggatac cttctgtatt    147660
     cctggttact tattcctcga gaaatcggac attaaaaggg tgcaaatact gtggagaaat    147720
     tataagttac caagtcaaaa agcgaatgag aatctattgt tgcgattttt ttggttacta    147780
     cttcttaccc gaactaactt tacataataa aaaagcatga agcgcatatt cagggactca    147840
     aaaatcccaa actggcactt ctgtatatac cgatgagcat actttgattg taaaaaacaa    147900
     cattaaaaag aactgcaaac ctgaaccaag aatacttaat ttcaaaaccg agaaatgagg    147960
     tacaacttgt agaagttcac ttaaacttat tgagcataca atctcaacaa aactaactgc    148020
     aaagtttgtt gctatagtca tatagtaata ctagcaggaa gccattaatc aaaaagaaac    148080
     tccatataaa acgtaataaa tattatgaat aatagtacaa tataagaaca aagacgaaga    148140
     aaatacatta taactgaagt gccaatatta gaaaaaaaaa aggtggaata tcctagtgga    148200
     aaaatatcat ctatgcggtg aaagaattaa atagatacta tggattgttt cgatctatcc    148260
     ttttatctgc tgcttgcctt tttttttcat tctccttctt cagtcttttt ccataggcga    148320
     gtccacaggg actacaaagt tccctgtttt ggtcgggtcc actacgccat tgaattgtcc    148380
     aagtgtcttt acatttagag cattccttta tctcaccatt tgggaggatt gtttgtctct    148440
     tttctctttt aggacgacta gtagtctttt tgctgtattt cttcgtaata ctggcagacc    148500
     gactagttcc ttgtgcacaa ctatggtagc cttcaagatt gtttgcttct tggctagtcg    148560
     tacgtctctc ggaattgcat gcactagtta cacgattctt tgagggtgta atttcgttca    148620
     aagagctggt tttgttctta acaatatttc ttgtaagatc tcttagttgt tcggcattct    148680
     caattttttt ttcaacatca acagccctta tttgagaaaa ggatacttca ataaatgagc    148740
     aacttgcata aactcttccg cgttccttat atgccttctt tttatcgttt gacttccagt    148800
     catcaatttc tctatttaat aataacgttt tctccatatc tgacttttta actactctag    148860
     ttaagaagga acttccagag ttgtcataat tattatatcg catactagca atagtaaatg    148920
     tctggttatt tacctagcaa cctcttaaca aagcgataac aatgaaacag caatataagt    148980
     ctatttaatt gacaacatca ttgataaaag tttgaacaag cgtctaaaag tcgaagaagt    149040
     tcatttcaaa gttttgtgta tcgagcttga tgatacttat ttagggatcc gctctagttt    149100
     actgtgatac aactgaaaaa cattacaaag ctatcgcgcc tgcattctca tattagtggc    149160
     gtatgtttgt gtcacattcg atacttctac ataatacaat gactgaaccc ttaccgctgg    149220
     cacaggaata ccgcgccgcg aaagcagggt ctaggagaaa caatagaatt cttggcgatg    149280
     agagagggga aggctttaat aaaaaaaaat agcgcttatc cgattctgtt ggaataagtg    149340
     gctatcaata tttacatgtt gatatggtag taaggatata aatgcttata ttgaatattt    149400
     ggaataagca tcaactatca cttattgaaa aggactcgaa caaaaaaata tgaaatgtcg    149460
     aaagccacat cactgagaag ttgttggatt gaagctctaa aatgtcatct tttagtagta    149520
     ttcgtgttac tagtatatta tcacatgcgg tgtaaaaaga tgacgtaaag attgagaaac    149580
     agtcatcaac tgttatggaa gctgaaatgc aaatattgat aatgtaatag gataatgaaa    149640
     cgtataaaat gaaaaagaat aataaaatat tattatgtag aaataccgat tccattttga    149700
     gaattcctat atccttgaga agaacttcta gtatattctg tatacataat attactgcct    149760
     ttatcaacaa tggaatgcca aaaattatca aaatatcacc caatattcaa ttttattgtt    149820
     gtgaagacat caagccctag atatatatca tagtaggata aaatagtaga ataaaactat    149880
     tcatatatct acgtgaaagc atcagagatt gtaatgttga gcgccgtggc gcagtggaag    149940
     cgcgcagggc tcataaccct gatgtcctcg gatcgaaacc gagcggcgct attaaatttt    150000
     ttgaactgtc cattaataat aatggaactg acgtcgtcaa ttaccggtag cttttttgcc    150060
     cacattttta atcatctttt aagtatttga gtatttgttg ttcactagag ttttactaat    150120
     taaggttctg agaaaataaa gatatgcatt tagaaaagtc ggttctacac cgcaaatttc    150180
     tttattacag aaacatttta tacaaagagg atacatagtt attggaaaga aaatcaatta    150240
     tctttttgtt gggtagtatg aatattactt gtacattatc atatacaata taaaaagatg    150300
     tcatagagtt gtgaaatatt tattatattt aataaaagct gaagcgcaat gattgaaaac    150360
     gttttaggat gattaatgat aaagtacaaa atgaggagaa gaaataataa taacataaag    150420
     tggaaatacc ggttatcttt taaggatatt ataacctgga ggaaaacttc ctgggttctc    150480
     tgtatattca acacttttcc gttatcaaaa atagaatccc aacagtatcc ccattttcgt    150540
     caatatctcc ataacgacaa ggtcttctag ataccatata atgacaataa ccaagcccac    150600
     catttaggtg gattttttgt gtggttttga aattaaaaca tttttagagg aaaattgtga    150660
     tcacagaatt tcacattccc agttacttta ataatattca tagttagaga tgaagaggta    150720
     ctattaatat gaaggttaag tatgaatctt ctcatgcttc tataagcgag ggatataaaa    150780
     catcgccaac tgtttcatct tatttattat caatattatg tgtgtttgga gcttactata    150840
     cagttaatgt gataattaat ataactcttg tataactacc atatcaatgt tcaattaata    150900
     gatcttaaat cggtttcatt actacctgaa ctgcatgtat gaaatttcct tccacattag    150960
     gcacattcac atgtaatacg agatgtacat ctatatgtga tattagcatt tacacagcaa    151020
     tcctatatca ctattaatgg ccacttgttc caaaaagtat atattatgaa gcgtattatt    151080
     attttatact cagatagctg gtgcgatacg ttcgcagatt ttgagcgcaa tgcaatgagt    151140
     atgacggaaa ggttcactca taatttcaat aactcaagtt gtttgaattt aaaatacatt    151200
     ccccgttaga taagctataa acattgttac ttgcgcttgc ggcacatgta atgtagtttc    151260
     tttctttttc caagaaaaaa gaaagccctg tagggggctc gaacccctaa ccttatgatt    151320
     aagagtcata cgcgctaccg attgcgccaa caaggctctt taattatgaa aaattacgtt    151380
     taataagtga cttaaaaata taaatactgt tactaaaatg tgaactaaaa cctcaatatt    151440
     attttctgat cacttgatga atagctggta attgttggat tccattgttg gtaaaggcta    151500
     taattttacg tatatagaat tgttggaata aaaatccact atcgtctatc aactatagtt    151560
     atattatcaa tatattatca tatacggtgt taagatgatg acataagtta tgagaagctg    151620
     tcatcgaagt tagaggaagc tgaagtgcaa ggattgataa tgtaatagga taatgaaaca    151680
     tataaaacgg aatgaggaat aatcgtaata ttagtatgta gaaatataga ttccattttg    151740
     aggattccta tatcctcgag gagaacttct agtatattct gtatacataa tattactgcc    151800
     tttatcaata atggaatccc aacaactatc tgaaaattca cgtgattctc atgtgagtac    151860
     atcagaaaac aaccacctaa caaccgtgtt tgaatgttga tctgaaaaca aaaattaatc    151920
     tctcgtactt attatggata ttgtattttc tcaaaattcc aaatgatttt cttgttagat    151980
     ggtattcacg gtcatcggaa tctcagttca atatcaccaa tttgcttata aggtttatgc    152040
     aagataacat gtttggtctt gttcccaagt ataacttaag aaaaaaaaat tacaatccaa    152100
     gaaaggtaat acagaattca tagcaataat ggggtccatt ttcaatagat aatgtacctg    152160
     gaagaaaagg gctgactagg aaacaaaaag aaaaacaaaa ctatgatact ccatcaaaca    152220
     tagggaaatt tactcgaata tgaaaagtac aaatctgtca aaagcacatc gtatattgtc    152280
     ttggttccgc ttttattcag aagaattact gaaatgaaga ggaatgacgt aataaacaaa    152340
     caacgattct gatatcagaa agacatcttg aatattccta tgtagtaatt aactatccca    152400
     gtacttacaa acataacttg acgatgcacg ctacgatttt tgtgtgttta aacttttgtt    152460
     ggttgggact caagaagatc ttctctgaga taattgtaat taaatgtact ttaggagtgt    152520
     tcatgtataa tttgcctctg caaaaactta ataatgtatt ttaaaacttg catgttgctc    152580
     tgtgaatctg aatgtatgat aatgctacga ttactctagg gaacttcctt tttacattta    152640
     aaatttccga gatcctcagc tgacaaataa atgtcatatc aagacaataa acggtagtgc    152700
     taaagtaatt gcatattaaa caggcgcgac taaagctttc atcccttcta ttattgcata    152760
     acctggctat acatgaaaac acttctcaca tttgatttaa gaagtttact gttctaagaa    152820
     aataaagaac gtgataatga tgaatgaaga ggattctaca gaaacgaaaa gcctagtcat    152880
     aactaatggc atgtttatca tagacgacat cgagcgtagt aaatataata ttcactataa    152940
     gaatgtccca ggaggcggag ggacttttgc cattttgggt gcatgcataa tatcttccgg    153000
     caatgtcaca tccaaaggtt tgaagtggat agtggacaga ggctctgact ttccaaagga    153060
     agttataagg gaaatagact catggggtac tgatgtgagg tttcgagatg actttagcag    153120
     attaactacc aaagggttga attattacga gggaagtgat gatttgagaa agttcaagtt    153180
     tttgacgccg aagaagcaga ttaacgtcga tgactggatt tccacatttg ggcagaagat    153240
     aattgatgaa atgcatgcgt ttcatttgct atgttctggg tctagatgct tagacataat    153300
     aaacgatctg ctacgggtga aaagttcaaa gggcacaaaa ccaatcgtga tttgggagcc    153360
     attcccagat ctttgcgact ttgatcatca aaatgacatt aaaagtgtaa tgcagaggaa    153420
     cgatgttacg gtaatattat ctccaaatgc cgaagaatca agtcgcttat ttggtttaag    153480
     tagcaaggaa ccgactagtt tggaagaatg tctagcatta gcgcatcgtt tcgatgattt    153540
     catggatgaa aacaatatgt gtattctacg atgcggtgcc ctcggaagca tatcggtaag    153600
     tgagaagttt aagaacggac gaacctatga ccatttcccc gcctaccatt tcaaaactca    153660
     gtctaaagta ctagatccta ctggcggggg aaactcgttc cttggcggct ttgcagtttc    153720
     ttatgcccta acgaaaagct tagatattgc tagtatatgt gggaacatcg ctgcaggcgc    153780
     aataattgaa caattcggaa taccgaggta cgatccaatt gctaaaacct ggaacggaat    153840
     cacattcttg gatagactga aattttacct ttcacagtcc ggtcttcaat ataatataaa    153900
     cgatctttac aaaagtctaa cacgatgatc atatcagctt gttcattgct cttatttttc    153960
     tgcaaaaata tacatatata tatataagta agtgttatat actacttgag attaggcgtt    154020
     gtaacaagat tcaaaaaatt cgaactcgaa ctgtgaaacc ttcacaaata tgctttccac    154080
     ttcttcgacg ggaaacttgt caacttcagc ctttagaaat tcacaccaag tttgaaaatg    154140
     ctcaccatca tgtaaatcaa tccatttttg atatttccaa tgcaaccctg gggctctagg    154200
     agtatcacga gcccatctcc aatagagttc ctcagcaacc cataagctgg ttactaagga    154260
     tggccatgta attgaggcgt cctttctcag ctcatctaag aaattaatat acgcatcaac    154320
     gccggggatc gctttattgt caaaattatc tctttcttcc ttggtgaggg atggtgccaa    154380
     taattctaag cagtcatgaa agtatgagtt ttcatcatta gaaaaaaatc caatcttttt    154440
     ggctaaggtt attaaagcgt gagtagttgg tgctaaagaa gtcgtcttac atatcaacct    154500
     taagctagtt tcaaaaaatt gcagatcttg tgataaatag atgtacaaac tacggtcctt    154560
     caatgttccg gcacatagtt ccttagcgaa tttatgttct gtggttttcc taacaagggc    154620
     gtcgtacttt tgtattaact tatcagtggt acagctcatt gttcttcctt gcagatattg    154680
     ttgatattgt tattatttgc gctaaatttt agttaataca gaaaaaaata tctaagttca    154740
     gtccagttca tattcgttta tatatctttc gaagccagac cttttttgcc aagcaattgt    154800
     tactatggaa actattagaa ccatatgcgc taaacaatat tagccatcaa ttcaacttta    154860
     ttcgcagtaa gctcctgcag aacaggctta tcaatcatta tggtcttaac ggaacgccta    154920
     gggacgctga ctaggcccat cattctacta ctggagccca tacgttcctc aacatgatct    154980
     aatagcaaat tcatttgggc atctacagca accaagcttc caactaaaat acgatcttct    155040
     gtaagggaaa ctattaaagt atttccaata aaatctgaca gtttcaagat gtccatgacg    155100
     ctttggtgcc ccttactaag tttgttgaag actatcttca ccctatcaat gatatcatcg    155160
     catttaaaaa atagtcagaa ctcatgcact tcgcgagata ttttttgaaa aaaaaaaaat    155220
     taatccgcca cataagatgc acaaaatgag cctataacat tgaattttat gatagaacga    155280
     aaggattgtg ttatttagaa cagagtatca gtatatcgta tgtcacagaa caacacaatc    155340
     agctcaatga atcctgaaag agcttacaac aatgtaacgc tgaaaaattt aacagcattt    155400
     cagttattat ctcaaagaga aaacatatgc gagttattga acttggtaga aagtacggaa    155460
     agacacaata gtattatcaa tcctgaaagg caaaggatga gtttggaaga aatgaaaaaa    155520
     atgctcgatg ctttgaaaaa tgaaaggaaa aagtaggaaa acgcaacatt cacaattgta    155580
     agctacaaaa tattgaatgt gaatcctgct tcattacaaa tgaagaattt caaagcgtat    155640
     ctagttcacc aaaagtcaca atatcttatt attatttgga agcttttata tgcatctaat    155700
     ggtcataaat cccatctcac tttataaaac aagttaccgc gaatgtatcc agtgatacag    155760
     aatagagtgt aacaaatgag aataaaaata ccatattatc gtttaatttt ggtagggtac    155820
     gctaaaataa agtggtgttt gcgtctccat ataactaaaa agaattgaaa tggcctacta    155880
     tcgattagac tattcaggca tggaagcagt aagaacattt cttgattttg gaaaaatgag    155940
     attagattat taattattgt gtttgtgtat ataatttatt ttgcatattt cataaagaaa    156000
     ttaaaattag attattaaat attaagtttc attagtgaca ttaaaagaag aaaactgatg    156060
     ttttgaaatg tgttaagcaa agaatgatta agacaatctc aagctgctct aagcagtatc    156120
     ttcgacagct tgctctgctt caggttcggg ttcgtggatt gcagtctctc cagatgctct    156180
     tgggctctct ggaacagctt cttttgtttc aggagccgca tcttccacat cgtccgtagc    156240
     atggtgatga gagaatcctc ctgtcaaaga tagccttggc aatttgccat cacggctgac    156300
     tgcaattagc aagtaacatg gataaatggc aaatacacat aaatccaaaa caccataaaa    156360
     gatagcctca ccgtctggtt gaatacggtt accaccatca cttagacccc aacagataaa    156420
     gtacaaccaa acgattacca tgcaggtaca cagcataagt gcattgaacc ctctagtttt    156480
     caaattgaag aattgacgtt ggcatatcac accttgggta accaacatag cgacagcacc    156540
     aatggtgtaa taaccccact tgtaggtgga cttgatcaat gaaccaacta atagcgaaac    156600
     aacccagaat aaggtaccca cgatttgaat taacagcgaa tgtaccatat ccaaggcgga    156660
     aatgtcgtca ttctcaccag tagtactagc ggctaactcg attaaaaata aaaggcatgg    156720
     ccaggacaag aaccaggcaa tatatttcga gtaaaagatt tgtctaatac cgggaacttc    156780
     acctgtgata gacttgctaa ccttgacgtg gttaaattca gcttgaacac cagtccaacc    156840
     taaatcagaa gcataagtga agaaagcaaa aaattcaaag aaagtgatca aaaatgcagg    156900
     agctaaggca tatctagtca atctggagcc cttgttctcc gcaatgaaga acatcacaac    156960
     atagcatagc aatataaagc caaagactgc aaacactgcc cataaccaat ccgaacctct    157020
     cttggtaatg tgcatatcca ggccatgtgg tggattaagc cctaaagcct cgttacgatt    157080
     taaaaagctt gatagcgtat cgttcatttg aaatttgttg tttttagtaa tcaaaagata    157140
     ttaaagtctc aaacttgttg ttttgttttt gtaattataa ataataataa ttgagttaat    157200
     atttgttgtt gtgttgtatt gcagaatgta aaaacaagaa acaagattag aaagtgaata    157260
     ggtgttacgc taaataattg aagactctca cagacttata tatgattttt ttagtgtgat    157320
     acaacttgta atgaggtaag ggattgatat tatactttct aactgatgat gaatatgaaa    157380
     actttggcca attagggaga ggaaagtttt cgatgagatg ctagaaaaaa acttgtcctt    157440
     gccatagcag aaagggatga tgaaataacg aagatgagct aatttggtat tcgaataaac    157500
     atgcaggatg tggcggaagg gatcggaata agagtcggga tcgggatcgg gatatggctt    157560
     tgcttacttt agccatacca aatattctta caaagcacgc tttcgatgcg tttttgcctt    157620
     ctgagagaat cctcctacgg ctcgaccctt gaaaaattct agaggatctg gaaaatggcc    157680
     aacaaaatcg cgcagggaga cgcaaggaaa gtaagtcaga tggatccgac tgtatgtaac    157740
     aagggttgct gcagcggttt tccatccctt tcggcaccct gcacaagtag ttattcttac    157800
     ttatgcaaaa cggatatgag ctacatagcg ttcatttttt aggttttcag aagctattac    157860
     aacgcagtaa aaaggataca caactttctt acggggaaga agaatacggc tcaatgcacc    157920
     cacttcaacc cccggtatca cgcggcacta aagttgtttg attgtaatag taatactgct    157980
     gttgaggttt tcttcttcag ggctgctcac aacgtgatat atttgaattg acaggacgta    158040
     ttcagcgcag ttgaggaaaa ttaacatatg acatgcgcag gaaataagtg ctcaagtttt    158100
     ctacttttga agaaaggact ttggtttact tgcctactat ctccatgtca agtactcggt    158160
     tgtatgatgt taaggagcgc agggaacact aatcgataaa aaacccttat tggctattac    158220
     taaatgtaac ggccgtgctc tagtgaaatt tgtatagaaa aatgggttct ctcgctcaaa    158280
     atgggcgcca ttacttgtct ggtcaaattg agttcctgga tataattaca taaacggatt    158340
     gaaatttaca taaggagtat aataattccg gaaactatct tgagtgcaat gccatcacgc    158400
     ggccatgcct tgacataaca tgctctcatc aaaaaggtgc aaattttcgc cagttatggt    158460
     tgatatctaa aatctactgg agttcatttt tttttttatt agatatcctt tttgcaagcc    158520
     ttctgaaaaa aaatttctca tgtggtacag cgttggttac ttaagctgct taaactagat    158580
     cgatgagcca ttcttaaatc agaagactgt gactgcgaat tgtaggcatc ttcactaccc    158640
     tgtccatgaa gctcattttc gttatcatca attggtgcta tcttataact ttgataaaga    158700
     gctaccatac aaaaaagact taacgaccac caactgaccc aggcgacgtc attttgctgg    158760
     gaccaagaca taatatagcc ccatactaag ggacctatga aacgagcaga ggcagaaata    158820
     ctaatggtgg cgccattgat gactgatcta caactcaagg gactcgaatt atgaattaat    158880
     aacataattt gtggtgacgt taaagcgcca caaaatgttt ttatccctgt gattatgtac    158940
     aagtagacga cagtatacca gctaggaatc cgttcattct gtagaaaaac aacgtaagga    159000
     accataacgt acataatagg gtacagcttg actaaagttc tgaaaattgt taaacaatcg    159060
     aaatttcgat caactatggg aaaaatgaaa ataaccacaa aacaaccaaa gatacctgtt    159120
     gtcgacaaaa gagtaccggt ttgttctggt tcataaccta taccgccaga tattttccac    159180
     ggaaattttg aagccagctt ctttggattt tctggatcta cggctaaatc ataagctaaa    159240
     aaaacaggca aaaattcgtt gtatacaatc aaatgtaaag ccataataaa attcaccgat    159300
     atagggtaaa atacttttgt atgaaaaacg tgatgaaata tactactttc tttacaaccg    159360
     tctggagctg tatctatatt ggcatgcaca gcgtctgttg gttcatgcag agaatatgtc    159420
     ctaatcaggc ctacagactg tcttcttgtt aaaataggat caatcgattg tatgctttca    159480
     gtatcatcgt cattggtagt attcactagg ggactatttt catcctcttc actatcttgt    159540
     cctcgaatgc tgttcacatt ctcattacgg tggtgaatgt tttccgaatc atcctgaatg    159600
     cgcttttgcc agggtcttct tttcggctgt ataccaaata tattcttctt aataaaatca    159660
     ccgacctcta aaccgtaatc tcttctatct ttaaaagcag gatgtgtttc ttccaaaaac    159720
     aatgttgcat tagttaaacc aaacatcaaa aacatgcaca ctaccacgtt tggcaaggcg    159780
     tacggatatg acctaattat tctttttgca aaatgtggaa accatagtgg cacttcattc    159840
     attgttccat ctctaaatac aagaaaccca ccgatcatag gcccaacaac ggcaccaaat    159900
     tgaaataata aaggcatagt actgaaagct aaagcctgat gttttctttc agttgctatt    159960
     tcaccaataa tggttctaat aacgccgacg ttaccattta gcaatcccat taaacttctt    160020
     gccaccaaag cctgatagaa attgcgtgaa aatcccagta ttaacaatga tacagatgtt    160080
     cctataagcc cgcaagtcaa tgttattttt ctgccatgct tttcagagaa tctaccccag    160140
     tggtacgcag atatgacttg gcataacgca aatgatgaag ataaataacc tgaatatttg    160200
     gacacttgag catcattggg agcaatatta aaatctctaa ccatgaaata aacataagga    160260
     aatagtgacg aaaacgcaat tggttcgctg aacctaacta aggacacaac aacaagttgg    160320
     acccagggga aaccatccat ttgttctttg aaagtaagct tttgacgcgc catatctttt    160380
     atattcgtgt gttcatatgc ttaccacttc ctagttcctt tgctagcatt cctttaggtg    160440
     atctaaattc aagctctgtg gataaggacc attatagtat tttttactaa tgatagatac    160500
     tttttgttat attttgtttt ggcattttcg tatccgagat ttccaatgag cggaatgtgt    160560
     cattctttgt caattaacat aggtcaggcc gaatgccaaa tggagtttag taccttcata    160620
     ttgaagaaaa atgctacatt attatattta caaggatggt cttaaataaa gcttactttt    160680
     aaggggggaa gaatggtgaa cagtgagtaa atacatagaa ggagataaga aacaaatgga    160740
     atatcaaaaa tcgatggatt ctgcagatgt tctataaaag ggtatggcat cctttatatt    160800
     atggttgcca tataagtatg agataaatct ctcaaaccct agaccaaagc ctccgtgtgg    160860
     tgcacttcct tcttttctca gagaaacata ccagtccaat tctccagatc tattcatccc    160920
     gcgtgctttc atttctctac ataacttgtc atagtcatct tcccttaaac tcccaccaat    160980
     tatttcaccc attccaggaa ccagtagatc aaagcatcca acagtatcgt caggagtgga    161040
     attttgtttc atgtagaatg gtttacaaag acgtggatag tcggtaacga aaactgggga    161100
     cttaaaatac tctccggcta aaaatttttc atgttcagtt tgcaaaggct gtccccattt    161160
     aggttcatac ttaaagtgtg aaacttcatt gtggcgtttc ttgagaattt ctattgcatt    161220
     ggtatacgtt atattgtgcc atttttcatt tattaaatct tcccatcgtg ttttaatttg    161280
     ttgtgtctct tgatttattg atagctctga cgatgcatta ttttcttgtg aagagataaa    161340
     ttgcttcggc aagagttctt gttggttatc tatacaagct ttaattatgt gttttattgt    161400
     agtctcaaca aacgatgtta gctcgttgac gctattaaca aagcacattt ccacttcaag    161460
     catccaaaac tccgaaaggt gtcttggagt atcactcttt tcggctctaa agcaaggaga    161520
     taacgtccaa caccttgaca gtgataacgc taaaatttcc aagtgcaatt gagtggacac    161580
     agtcaaataa gtcggcttcc caaagtacga ggatgcagtt ggcgacgtat tggtggagac    161640
     ttgaaacaac tcgccggcac cttcacaatc gtttgaagtt aatattggtg gtgaaacttt    161700
     ggtgaagtgg tttttctgga aatatagcat gaactggaat tctacaaagg atcttaaccg    161760
     taaaattgca cttaagtaag cggttctgta ttttagtgta ggtaaggacc ttaaataacg    161820
     taaggtttga tatttctttt gtaatggata gttttctgaa acgggaccca caagtttaat    161880
     tgacttgaca ggatttttga tttgcaattc aaaaggttgt tttctattag gggtgctttg    161940
     ccaggtagca ttagatatag ataaagtttg accagttttc agaattttta ggaactgtac    162000
     ttcatcagta tttgtgagtg gaataactat tcttaatggg ttcacagaag tcccatcttg    162060
     taaatccaaa aacgctatac gttttaatag tcttatggat ttgatccatc cattaattga    162120
     aatgggatca tggctagtat ggtgtacctg ctcgtacaat gatttaactg ttagtgaaga    162180
     gtaaaatcta ccacctttaa ggaaggtgaa agcatgaaac attagctgtt tgtattcgct    162240
     tgttctcttt ctttctctct tagtaagcga taagtcgagc tctacttaaa ttgtggtacg    162300
     ttttcttttt ttcctataat ataaaaaaga taaaaaatca ggacgagaaa aagtagatca    162360
     taactataag ttgtgcatac tcatactcca cactcgacgg cctaatctct gtaaggattg    162420
     tattttattt tttatttatt tattatttag attttctaaa aataaaaaaa aatcatacac    162480
     tattttgatt acactactat gtaatttatc tttgaaaaca accatgaaaa actcaatttt    162540
     acacacacat gagttatcat gaggagtcat cagccagact taacaatcac acacattgtt    162600
     aagagtggaa aaaaataata gtgataaaag gaaaaaagct aacaatttgg attttacggg    162660
     atctgtctaa atacgaaaca cacactcgtt ttagttcaaa tatcataacc ataaaaaaaa    162720
     aagcacaatt caacttgagc acgcacacta agtagtaaca acgttcattt acagtaaagc    162780
     gaacggacga aacaaataaa agaaaggcat agtgagggat aaaaggtaga aagaattcaa    162840
     aaaagggtat cgcacacaca cacatagtag tctaattcat gttctagaat ggatataaac    162900
     aaagatgaag gggacaggaa ataaaatggc tcgctccgcc ctttttagaa tctttgcaat    162960
     cctctttgtc tagcttgcca ttttctgtag ataatggtag caataatggc aatacaagcc    163020
     aaaccgacca aaatgaaaac taaaataaca ccacctggta aagtcattta tgatagatta    163080
     aaagtgctga aatgggaaga ggagaaacaa acaaaggata tgtaggaaca aaagtttgct    163140
     tgagtgacta gtttgaagtt gagaaaaaaa aagagatgaa aaagttaact tatttgctct    163200
     tccttcaaag tgtgtagcgt cttcctttaa atactattga aagggaaaaa gaataaatgg    163260
     aaaaagggta gtaatgaaaa actctaaagg aagataagac gcaataagag aaaaaaaggg    163320
     aagttaagat tacaagagaa acaataaatt gctttcaaag ctttatatac tggcaagcac    163380
     ggaaggctaa atttgaaaaa aaaaaatggg aaattattat cggaaaaaat tgaagctatc    163440
     ttctattacg cagtgacaag tctatattga catctttctg ctttctgctt tctgtttgtt    163500
     gttttttttc tcatagttgt tttgatttta ctctgttgga aatgcgaaaa ttgttttgat    163560
     tttacccgat tgcgacctat tcccggcttt cccaaaaaag gaattcctgt ccaatgcaac    163620
     gacagccata gaaacagccg cggttgggtg cgtgggtgcg gtaatttaac gatcatatgg    163680
     tatgggtgca cgtgggattc taggggaagt gcgcgcggat accgaatcgg ccatcgaacc    163740
     ggccacccgg attgagtttg gtatgttgcc tctttgcgca attttattga atgcaaagtt    163800
     tctccttcta gtaaaggaca acagctgaaa aatgctcgat gtccaaatga cgacataaac    163860
     ctcctcgttt aggaaagagt taacacgcct agtttcagct tgtttctttt tattgtgtaa    163920
     ttagttttct tacttagtac atcttattga ccccactgtc atcggatgtg agagagtggt    163980
     tcacttctga attaagttta gagatatact aaatctaaat aaaagtctct ttctgcgtgc    164040
     atatgttttc ttgcgcggga ctcacaagga tgcgtctttt atttcataac gcggttgtcc    164100
     caccttaagc ttaggtatca gaatcgacta aatcgtcgat gctgtcaatt atgtcgtcaa    164160
     tgagatcttt tgcgtcgttg attatgtctt gaagccaatc ccccactgtg ctagcagtag    164220
     cgctagcttg tatgctgctg ctgctgctgc ttcttgatga tggtgatgtt tcgcccagta    164280
     gagtctcagt tgctgatggt attgaagttg tcatttctag ttttatcgtt aatgacgaag    164340
     atggcatagc ggctatttca tcagtgtttc catcgtcgtt gtcatcatta tcattgtcaa    164400
     cattgtcttg ttctgtctct tcggggtacc cgccccaaat tatattataa gtgctgaatt    164460
     caccaaactt actgaccaaa taatcaaagt catcttcaat ctctacttct tcgctgctct    164520
     ggggttcgcg gagttggttc ataagcatcc cagtcccatc attggaattt ctgtcctttt    164580
     ctgccacacc gcaaatatca cacaaaaggt tgtaaatttc ggtattttgg aacggctcaa    164640
     tgtatccctg tggaaaatat ggccccatac caataaatac agatctcata tcgatcgcgt    164700
     tattgtcgta tccatgtgat ccaatcgtga acacattgtc ttcgtttttg tccttatgat    164760
     caccttttgc caccttcttc aattgttctt tcttcatcac tgcataccca ggctcgggca    164820
     caatccagat tgacgccatg tgatgatttt ttccatcatt aaagttccat tctttgggga    164880
     aatttccatt aacgtaaacc gtatacttgt cttcatctat agaagtcttt aaattgtggt    164940
     aaacctcatt gatgtttccg gaatctttca acgatatagc catcatcgga ccctctagat    165000
     atgcgtgcga tacataatcc ttcctcaatt tttcgtccag taagtcttcc catataataa    165060
     catttgaggg aactacgata tcgctcatac catgatcgct aacaatgacc aaattagtaa    165120
     agctggttaa atttctttct tgcagcgatt ccactagttg cttcagaaat gtatctactt    165180
     cccccagtgt ttcagtgaag tcttcataat agtattccga ctctgacgga tatccatgct    165240
     tatgtccaaa ggcatctacg ttcggtacat aaccgagaat tagctgtggt ctttcgttca    165300
     gtgtactcat atccacatat tcaataatct tggataattt ttgcgaaagt ggttctttag    165360
     cattgaattc gtcgaagtaa aatggagttc tctctctagc aataggattt ttatgttcag    165420
     gttgtagttt ctcttcatta tacttggtat aattcacatc gctacctggc cacatatggg    165480
     tagcagcttt gaatggtata tcaccgtcaa atgcagactg aacagtttgc catattggtt    165540
     ctgtatcatt attgttccat attcgagggt ccaatacacc tggatggaat tcctcattaa    165600
     gatcaggatc ccaaaatacg ttagagacta taccgtggtg tattgggtat tgtccagtaa    165660
     ccaacgtcca atggttggga aaggtctccg tagggaagct gggtaccata aaaggtgtgg    165720
     acgtgatatt catacctcca tcatatttca attcatataa gtcatgtaaa aacggtgtgt    165780
     tcctcttaga tatgagtgaa ggatggaaac cgtctagtga aattactatc gttaagggga    165840
     aaaattcatg cgtaccgtta aaatacttca cgtaagggtc aaattcagga ctgccaaagt    165900
     gcgatagcac tctcgtggag tgatggggtt ttgctatgtt aatcatcaga attaaaaaaa    165960
     tggcaaacac cagcgagcca aacaatgtgc gaaatattat tttaaaaggc actttggaat    166020
     gaaatcccgt tccaaaagaa agttcattct catcaacaag ttcagtatca atgggttgac    166080
     cattcgcgtc taattcatat agcggtatac cccttctaaa gttagaacca tccctactat    166140
     ctttcgcgtc gccaatcact atgggattgt ttgtccactt cagtctattc ttataaaacc    166200
     aatatttcat cctggtccac gcagatcgcc accccgatct tacagcatct tcatccgtta    166260
     tgaaatcatc acgaaatgga tcttcactaa aatcattcag ctcgttatcg agcgactcta    166320
     aatcattctg aagttccatc tatagagagt gttatactgt acctcttttc agatatatgt    166380
     aattacctcg cctcacttat tttgcttatt tgtggtttgt taggcagttt gcatatcgta    166440
     ccaatgtttt tttataactt catgtctttt cttttttttc atttttagca tcgtacgcag    166500
     atatcttgtc tcgttatgat attttgtgag ataggtatcc aaaattaata agagaaaatg    166560
     tcgtattgtg ttcacaattc acctgattgt ttgactagtc caacccctgg tataattgtc    166620
     acttaatata ttcttagctt ccaggtgatg ttttattcca ttatttatgt tatgtatata    166680
     taatcgtaac tcttagagca aaaagtaaaa aaaaaggtgg tacttaccga gggagaatat    166740
     atacaaattt attcgtaaat gtaaataatt aattgaagca gagctaaaag aaaaatacaa    166800
     gaaaatttat ttacactcgc tgtttggttc tgatcttttg gtattcacaa ttttagtgct    166860
     gtccaaaaat attgcgatgt gctgataaag tacatagtgt gatccgactt cgtcccagtc    166920
     aaagaaagga tgaaatatta gttagtacat ttactggttg ctactggatg tcctatctga    166980
     atcttccatc ttaggtacaa aaagattaag aaagtcaatt gtccttagtt ttaaaagaca    167040
     gttacttcat gtctttaaca tcaacggcaa attactttga aaaaatgcac taaaagttaa    167100
     cacatgtagg agcattctaa acatgaaatt tttaatggta cttaggtttg ctaacgcatc    167160
     ttgaaaacta gcaaaaaccc cataattaaa atattcttgc ttgttaaacg aggcgtccaa    167220
     gccattgaaa ggttttatca atattcaacc tcttactata aatgcagcac accgtaacag    167280
     gtatgagaaa gatgtggtat tattatacaa attgtactga ccgctttcct actaataaaa    167340
     ccaatgatat cctagggacg ctcgagtttt cacattatag aacatttatt attattttcg    167400
     gcatcaagcc ccagagttcc ttcgacacgt tccatttgtt tcaaaaggag cataaaagtt    167460
     tcttcaacat tataatctaa ctcggcactg cattctataa atgctgcctg gttcctctta    167520
     tcttgactgc caattgtcga agctagtttc tctccttcag ctttcgtgac acaccttttt    167580
     acaccttttg tactccttcc caaatcagct ttggtaccca caagtattac cgggaggtta    167640
     tccttaccca gctgatctac cagcttgtcc cagagaatgg gaataagatc aaagctagca    167700
     cgatttatta tactatagca cagtattatg cctcgtacgc ccgtcaacga tttaatgttt    167760
     aatagagaaa cttcatcttg gcctgcagta tctagaattt ccagagtaca gtcatgactt    167820
     ttataaggaa ttatcctggt aaattcattt tcaatagtgg gataatagga ttcaacgaac    167880
     cgcgattcta cgaagcgaac cgttaatgtg gttttgccga catttctagc tcctataaga    167940
     gcaatctttc tctgaaagtt atgtgtggag ttcgaagaag acatagtggc gtattccatt    168000
     atgtcacagg ttatatcttt tctcgccgtg ccccaataaa actgtttcgg taaagagaca    168060
     attcgaacca gcccaaaaga atgaatatga aaatatcaat atgcgtcaat gaaaatggag    168120
     gcaagttcaa taatttcact ggaaatataa ctagtaataa ttcgtgtaac tgctgtagaa    168180
     attgttagat attaaacctg gcagaagcgt cttgttaata cttatagaga aaccaccagt    168240
     agcgttcttc tgtatctgaa gatagtgaaa aatcaaaaaa ataaatctgt attcaaaaaa    168300
     aggtcctacc cggattcgaa ccggggttgt ccggatcaaa accgaaagtg ataaccacta    168360
     cactatagga ccaggacttc ttgtaatatt ttgtatctca aaatgaggta tgtcagtatg    168420
     acaatacgtc atcctaaacg ttcataaaac acatatgaaa caaccttata acaaaacgaa    168480
     caacatgaga taaaacccgg ccttccctag ctgaactacc caaaagtata aatgcctgaa    168540
     caattagttt agatccgaga ttccgcgctt ccaccactta gtatgattca tattttatat    168600
     gagaaatggg tgaatgttga gataattgtt gggattccat tgttgataaa ggctataata    168660
     ttaggtatac agaatatact agaagttctc ctcgaggatt taggaatcca taaaagggaa    168720
     tctgcaattc tacacaattc tataaatatt attatcatcg ttttatatgt taatattcat    168780
     tgatcctatt acattatcaa tccttgcgtt tcagcttcca ctaatttaga tgactatttc    168840
     tcatcatttg cgtcatcttc taacaccgta tatgataata tactagtaac gtaaatacta    168900
     gttagtagat gatagttgat ttttattcca acattatata atatataaga taagtaacat    168960
     tccgtgaatt aatctgataa actgttttga caactggtta cttccctaag actgtttata    169020
     ttaggattgt caagacactc cggtattact cgagcccgta atacaacata atatctacat    169080
     tctagatacc gacatatcaa tataaaaata ctgaatattg agacatcttt tagattacgt    169140
     tttggttgcc gcaaaccaaa aatgcaattt aaatgggtga ataatttgaa tggttagaaa    169200
     tctatttgtt ggaataaaaa tccactatcg tctatcaact aatagttata ttatcaatat    169260
     attatcatat acggtgttaa gatgatgaca taagttatga gaagctgtca tcgatgttag    169320
     aggaagctga aacgcaagga ttgataatgt aataggatca atgaatataa acatataaaa    169380
     cggaatgagg aataatcgta atattagtat gtagaaatat agattccatt ttgaggattc    169440
     ctatatcctc gaggagaact tctagtatat tctgtatacc taatattata gcctttatca    169500
     acaatggaat cccaacaatt atctaattac ccacacattt ctcactattc tcggtaaagg    169560
     ttataatatt agtgttggaa taaaactcta aaataccatc cattcagaag tattcatgct    169620
     actagcattt tatcacatga ggtgtaagaa gatgacataa agattgagat acagtcatca    169680
     aacctaatgg aagcgaaatg cagggattga taatgtaata agataatgaa acataagaaa    169740
     cagaaggtag gagtattatt atgtagaaat accgattcca ttttaaggat tcctatgtcc    169800
     tcgagtagaa cgtctagtat atacgaaata ttataccctt taaaaaacag tggacccaac    169860
     gataatcaca acattcaccg atttctcacc tgaacagatc acgatcatcc ttcagaacat    169920
     cttgctgtag ccatattaaa ttcctttgtc tctggactct ttctcgcgcg actgatctcc    169980
     caatgaagaa ctgcgtcagg tcatctcgtc ctcaatttct aaccaaaatt ggatgatttt    170040
     agttctcact gacgctgctt gaacgttaac accgaaagag catgcaataa tcacagcacg    170100
     gtaaaccaac ttgtgtcata tttaagagaa atattaaaac gctaagaaga tagctcccat    170160
     aatagaagta caagttatat ttatcgttgt ccaactgcag aagttaaata aaggtaaata    170220
     aatcgagcta agagaaaaaa aaagtatagg caaaattccg accggagcta gctttatctt    170280
     gctcctccac ctaagtcacc tgctcaggtc actcaagttc acaatcttct gagaggatag    170340
     ataaaggaaa aattggaaca gatcttttca tggcctggca attgtctgtg gattggtaaa    170400
     gctctgtcag tgaaaaaaaa agttctcgct ccttcttggt ctcttctatt gcctgagatt    170460
     ctaatgcttt ccttacattg tttcataaaa taaccaattt ttcgtgtcac aataatcttg    170520
     aaatttgaag tttctaaaat gcatcagaca tggtgtcgta attagttgac ttactttaac    170580
     ttctaccaag aagtagaaaa tagcagagtg cgtgaacgca tagcagagaa caaaatactt    170640
     actaaacctt ttcgaataag ttagcaagaa gcttttaaaa acatagactt agaaattgtc    170700
     ctgcacttgg caaggaagaa aagaaagatt agttaaacag aaatcgaaaa atgcatgatg    170760
     aaaaactaag tagacctctt tagaagtgtc ttagcggcta ttgttcatga tacttttgaa    170820
     aagagccctg agattttcca ttaccatcaa caggaccaat gaatagctaa aagaatcgaa    170880
     tgtatctatc ggaaaggatt tgaaatttcg gccatttcct cattatgaag ttcaacttcc    170940
     atactctcgt cgtcgccatc attttcatta tcctggttgt cgtcatcgtc atcttctccg    171000
     ggcatgtcat tagcatctat ataaggaacc tgtttcttag acaaattctc ttttatctgt    171060
     agtgagcgta tgacgaccga gacaattccg cttgatattg ccgtagccaa gagggcgtag    171120
     caacctctct caaacttggg caccatatct gaagcaaaga ataatataga ccaccatgcg    171180
     ttaacggccc ctgaaaacat attcatggaa gcaagaacga tagcacgttc ttgaagatct    171240
     gcatgacaaa taatgtttgc ccacgaaaaa aaaaccgctt gtccagcgta tgctacgcct    171300
     ccaagatact gtgcagaaaa gacgactttt ggatttagtg ggtctgcacg tattagtacc    171360
     gcaacaataa ccattaccaa tgatatgaaa acagaaacat gccaatgcct agctcttggg    171420
     atcttactca tatatacagc agaacaaagc gtagaaacta tacctacggc aaatatcccc    171480
     gaaggataat tatttctttg cgccaacgta tatttttggt tttgtaacca taatgcaaat    171540
     gtagaattag atgcgaaacc caagttctca cctcccagaa cccaaacaag agagaacatc    171600
     caccagtgcc acctttttaa gactctagga atagtcgacc agtctaaccg ggtgctttcg    171660
     tccctagcgg ggagccttct cctagcataa tgtagctctt gttcattaaa aatgtatctc    171720
     gtcatagaaa atttgctaac agcacttgtt tgatcaggaa ggccggggaa gaaaataaac    171780
     ccataaattg caatgggtaa tgtgatacaa aaatcaataa tgaataacca tctccaaccc    171840
     gccaagccat tccgcccatt caaatgagta aagatacttg tttgcataaa tccactgaac    171900
     atagatccca ccaaaccgct acctgtaaaa atagcacttc taatgggcaa ttcgtcttct    171960
     ttataccacg aacccaaaac aaaatgtgtt cctgaaaatg tgcaactctc aaataaggct    172020
     tgaaagaatc taattgcgca aatatgtttg aacgatgtaa ctttgtacat tcccaaggtc    172080
     aataaacccc aagcaaacgt acaaaaactt agccatatcc tgggcggaac acacaataac    172140
     attaaattat tggggaccat acctacaatg taaccaatca tgaaaactgt gttagacacg    172200
     gtcaaatcgt ttccgaccat cttaagatct tccttcatac cggatatata tgcattggtg    172260
     aaaccgacac ggtcgacata attaatccag tattgcaagc aaacaaatga tagcacaaac    172320
     aagtctattt taaacagaag taatctcttt ttaatggcac gcttggaaga aacagattct    172380
     ctctcaacct catgttgagt gatagatttc gattccttca tcatgactta ggcccaggct    172440
     ctctccaatc aaaaattctg aaaacagctt ctcaatcttg aataaatcgg aatactttta    172500
     tatcagaatt acaggtccgc ctcatttctc ttaagagccg atgtcttcct ttacaatata    172560
     cgcatgtaga agatttgatc gatgctgagt tcttgtaatt cgtcaaaaat gcctttcaag    172620
     atcgactact caaaatctac aataatcgga ctgcatggat caatggaggt gtaggcaatt    172680
     ttgtaacaat gaaggatatg ttaaattcgc taaagcttcc tcctcttttg ctaaatttca    172740
     tcatcaaaaa gcattttgca taacacacgt taaccaatat attatagtat atatacattc    172800
     tatttgagaa taagcatagt tttacataac tagttcgtta ttccaaatgt atttttccta    172860
     tttgccataa atattttaag taaaagaaag catgctctag ataaaaaata tcgaggaaga    172920
     gtcgaaataa gcaagcgtaa atattacaat tattctgaag aagcagcatt ttcttggccc    172980
     tcagcatctt ctaatttctt cccattcttc aataaattaa tgtccttttg aactaagctc    173040
     aaagtagtac ccttagaacc gtcgtctctc tcgaagacat agttagcagc atctgcttca    173100
     acatatacca aagcgctgaa taaattatgg aaaggaaatg ttagtaaatt ataacgcgta    173160
     attgtaaagt aagtaaaatt gaagaataaa taacataccc ttttctaaca tattctgtca    173220
     aaaaattgat ttgaggttca ttgaaaacgg tgatattata ccaattggtt tggccatctc    173280
     ttcttggttg cgaagcgata ctatatttca aataacgatt gttattagca gaagtatgtt    173340
     cagtgaattc agagccaatg cggccgacga tggacatttt cgagaagtcc atcttcttgg    173400
     tagtagcatg gaagaaacga gcttgagtac gtaaaaacat tacaatggat tagtggattt    173460
     ttgtttgttt tgtatttgtc aaggacacac aattagcaaa tgacttgtta tcaaattcgt    173520
     ggtatttgtc tttctcaact actgtgttag cttttttttt ttcgtctggg cgcaaacgcc    173580
     ttttaagcac tcctccacaa ataataagta ttagatgaaa agtcctaaaa gtccgaaaaa    173640
     tggaatagaa aagaacgaaa atacagaatc tttacagaac attatagtac ataagtgtag    173700
     ttctacgtaa gtcttaaaca aaggtttcaa aaggaaaata tgatttagcg gcgccacctc    173760
     cataaattat ggattagcaa acaaaagaac aattaatatt gaaaaataga agcatagcag    173820
     aaatatcaag cgagaccatg gtagttacca gtggtcaaag ttctttttgt gtttacatcg    173880
     agccactcac caccaaatgg attgttttca tccagctcct gacaagtcaa ggtgattcca    173940
     ctgccggctc cgctatgggg tagagccacg ttatccgtct cactgatagt gaatttggta    174000
     atcacgcctt tagcggattc atgtgccagg ccgtctgtaa taaatctggc gattaatctt    174060
     tgaccttcac catttcttgt caaaacaact ggttctttaa atctccacgt tattctcttc    174120
     ttttctttac tgaaggagcc ctgaggtttt gataaagcgc ttgttgcatt agcaccatcg    174180
     atattcacaa agacaacgag gtcttctatt acgatttgtg atatttcatc gggtaagctt    174240
     ggtgacatct tgacagtcaa tacaacactt gcctggtgag attcaaatct ccagaccgga    174300
     tgaataacaa taggcgcgat cggctccttt atggaatatt taatagctcc taaggttcta    174360
     gaatcgataa atgaagggtt aactttgaat tcttctggag caacacgctc aataaaggct    174420
     tggttcagaa tgaccttttc gaacttagcg ccattattga ttctcaaatt aataccgata    174480
     ggtaaaggcg aattcatgac agaattgggt aaatagttga gggcaatttc cccaatcagt    174540
     tgggagttct gcaacatacc gtctttgaaa gaagcattga gcacttctgc gatactagca    174600
     ttcaacccaa attgagatgt atctaaagag gagtgctgaa acaacgattg accaactaaa    174660
     gatgttgaag agcccgtggc ttgaggattt agttctctta gctcgccagt aatctgagag    174720
     gagagtgtgg aaactggacg ttcctgggga atagaggaca aggaagaaga agtaggggta    174780
     gcgcctgagc cgtgattagg caaagagtca tagagttgag aatccctgtt atgaatgaaa    174840
     ttttgtttcc ttgagggtgg taaagcaggt gcgcggatat gcaagggcct tgaatcaact    174900
     tgacctgaag gttggttatc aaccgtagca gtaggaagtg aaatactggg agaggcaggc    174960
     tcaactggta atggttttgt ttttgattgt ggctgaagtg gaggttgaga aattgatatc    175020
     ggtactgtct tgggtaagtt acttgagtct ggttctttcg cagtgggtgg agaactttgt    175080
     tgtggcgttg aaggaggcac ttcagaagga gtaaaagttt gcgcaggtgg tgtatcggca    175140
     gtaacaggtg catctacgtt tttaggagta gcatggggag gaagaggagg agtgtcacta    175200
     gcttcacccg gggtccaatt gtttgatttt gatgatgaat aggtgggtcg acgttgcttc    175260
     tgataaatag aagaagttgc agttgaagac actctggtgg aagaattatt cggagtctca    175320
     gtgatggatg cctgaatatg agagtttgat gatgattgtt gttgtctctt gttcttggtc    175380
     ttatttctac cgaaaattga gcccacttta gatcttaggg tgtgggacga cttttttgat    175440
     ttcaaggaag aattattagt agagtctgaa aattcgttat tcatgagatc attatgagtg    175500
     agactggaag atgcagaggc aagacgatgt ccaatgtttc caaatgcact cttacgctta    175560
     tccttttgtg gggatttctt ttctctttcc gtattagcgg caccattgga tacagagacc    175620
     gggcgggcac cagtggcaga agctggcgaa gcattattag gaactacttc tttggaagaa    175680
     gaggatagtt ggaagttgta ttgactggca tctttggcaa aacgatcaat ttcactttgc    175740
     ggttcgaatg ccaggaattt cgtcatcacc gtttcgcatt ctttggtagt atttagtaaa    175800
     taatcgctaa aactggtttg aaatctaagc atacagtttt ttaaagtgtc caaacggtta    175860
     tagtcaatag tctcgaacag ctcaaacaaa taggggcttt gctggtccca ttgccttctt    175920
     gcctcttcta agtgactaga gttttcgtta ttcttactat agtgctcaat tgaagctgca    175980
     tttttactaa gcttggaatg taagtccttg ctttctctcc agctagtatt gttctccacg    176040
     gattccttca attcacgaac gacttgctgg tccaaagtgt tgtagtattc tgtacttgac    176100
     ttcaaatctg attttagttc ttcaattaca gtatcccata catttcttag ctctcccagc    176160
     gagttgaatc tgaatgcact catttcctgc ggagtcaaaa cattactttc aatcatttga    176220
     gcgtttaaga tctttgttat atcttcattt tcagctatta tttttctcaa ttgctgagca    176280
     tagttcctct tcagatttgc caattcctta aataacaggt aaaagtcttt attcaacaat    176340
     ttgacctgcg ataacctgat tctaatagtt tcggtagcct cgtaaggact cttagtagtc    176400
     aatatgctat ctgcatattt ggttctttgt tccgtcatga gaggtgatta ttcgcaattt    176460
     tcaaataagc ttgcttcaat acgactacag caaaagtaat tcctttatta aggcaataac    176520
     tacgagacct tttctttgta tttcgtgaaa acttgaatgc aatatagagt ttttcaatct    176580
     gcaagtactt aaggggccct tttagctaca cataatatag aaatgaaaga tcacgggcta    176640
     cgaaaagcca ttcataatca tatacaaata tcacctgtaa tatataagaa tatatgagct    176700
     attgattttc ttctaccgcc tgatttagtt gttttcactc ttcaaaacta aattcagtat    176760
     tagcgacagt ggaggtgcta gtactctgta aatgaaagta aacgctggta ttcatgtaga    176820
     gcaccaacct gactgtgaat gcgtaagctg aaacatgata gccgcctgta aaatattgtt    176880
     atcaataagt agaccggctt acacgaatag gattcgcttt attctttact ccccactcaa    176940
     ccctaagcaa tgttcaaaat agtgtgagat tattttatgc gcgcctcctt caaaaaaaaa    177000
     tttacatata taacataggt ggaaaaactt ccctccgatg tctaataagt taatcaatag    177060
     aatgaaatgg acacgaaaag gcgtagacat ggaagatgac aatgacgaga acgtcatttt    177120
     tttttccacg tattttaaaa aggggtagcc tgcttcacca gatgttcttg tcaacaaaat    177180
     tctaaaatga tgattttttt aaacacaatt tatgctagat agtatctgaa agcattcaaa    177240
     ctttatgatt acagtgtttt cgacagtttt aaatctctga accgattttg taactcttgg    177300
     taattgtgtc cttacatttc cgtaatgacg ttaatcaaat cgcaatcttg aatcttctta    177360
     actaaaaggt tataagggct tttttttatt actaaattga cgtatgagct gatttgatta    177420
     tgggcgctat ataattatat gtacacattt tttaactgta aaaaataata cggcaataca    177480
     agtacaatac atgcataact cataatcttc tacctcttct accacccttc tttctggtgg    177540
     agtcagatgg aactggggta acatcttcga tacggccaat tctcaaacca gatctggcca    177600
     aagctctcaa agcagcttga ccacctggac ctggagtctt ggttctagta ccaccggtag    177660
     ctctgatctt aacgtgaacg gcagtgatac cgacttcctt acacttagcg gcaacatctt    177720
     gggcagccaa catagcagcg tatggagaag attcatctct gtcagcctta accttcatac    177780
     caccagtaac tctggcgatg gtttccttac cagataaatc ggtaacatga acgaaagtat    177840
     cgttgaaaga agcgtaaatt ctagcaacac caaaaacttg ggaattgtca cgagcttgaa    177900
     caacgtctaa atggaaatag taaatcgata tcggacgata tcaaacgtaa tgttgttagt    177960
     atccaaaagt tttttttttt aattcttaca tagtatcttt gcttttccat cgaaaaaaaa    178020
     gttgacaaaa tatactgcca ttgacacaat aggctcaact aatcgctatg aattactttg    178080
     gaggcaatga attcgttgaa ttgtctttat gtttctgact ttcaatgtat cttgcacgtc    178140
     gtcagaaaca ttcaacaaca atcaatggaa aatagagatg ctttaaaaat gttcactatg    178200
     tgattaaaca tactagacat ggcgggttct tgtggtttct tactctcctt gggtttaaaa    178260
     tagaatcttc attaaaaagt gctttctgta atatatagtg attaataacc aattcatttc    178320
     aactgtctac ctgaggaagc cctgcaccat atggaatgag ccaggaggcg ggatggtctg    178380
     ccgcaagcag acaaatttgc caaaatgcag tagagaatgg caatgctcgt gctgaaggtg    178440
     aaaaaaagaa cgcaaaaaaa aagagtagta aaatgtacag atgtttatta agtccgtaca    178500
     ccgcacgtaa gtactccaaa gcagtctcta ttacatttta aatagggaga aagaagatac    178560
     ataacaagta tgaacaagaa cgataatcag tgagtaacaa gaatagagat gtcaggcccg    178620
     tgtgaagtac ttgaaagtaa taagtgagta tatagaatat accagaactt gtaagctttc    178680
     gaataacaaa aagagccatt tgtacttatt ctcgaactcg gttgtagaga ggacgttgcc    178740
     ttgaaagtca caaatcccct acaataatac cggtccttgg aatgtaaatt attttgttaa    178800
     ttttcttata agttcacagt tgaaaaaaca acggtcacag tgaatcaata aaagaaggat    178860
     ctcactttat aaagaaaaga acaggaaaaa aaaatgtata tctgggtata ttacccggcc    178920
     cttgataata tttttcaata attttgccag gtaacaatgt gattcatgca tggcttaaag    178980
     aaaatacatt gctgaagcaa aagctcacca aaaatttgcg ttgcaaagct ttgtttgcgg    179040
     tatgttaata aagttaccat gaagcttttt tactgctctc agaccataaa gacaggaagc    179100
     aacttgtcat atctatttcg acttcagcgg ttattttctt cagcccattg ataaggcgat    179160
     atatgcctag aagaaaggaa gagtgcagac ttgataataa agcaagacca agagcaacta    179220
     aatagactaa aatatagagc cttccaaact gttagttatt attacttaat actcgtacgg    179280
     gtgatgaagg tagtgacttt gtaatccggg taatggggaa aataagaagc cttcaaagct    179340
     atagcatttg tccctactgc atcggcccct ttccagtaca atagaatctc gttgatgtga    179400
     ttactgattc aactgaccca aataaatcat ttgaagaact cataaaagga ctatagcagc    179460
     aagaactgca agccaattgg ttctttctcc tttctgccaa aaaaaaacac aatacggata    179520
     tgaattcaat tattaatgct gcttcgaaag tcttaagact ccaagacgat gtgaagaagg    179580
     ctactataat attaggagat atactgatat tacaaccaat taatcacgaa gttgaaccag    179640
     atgtagaaaa cttggtacag catgaactaa ccaagataat acaaggttat cccatacagg    179700
     ataatatgat tattaatagc aaaaaaggca cagttgaaga tgacttatgc gaactcaata    179760
     actatacctg ttttgcactt tcgaaaagct ttgatttatg ccatgatagc agaaatttca    179820
     acatagcgca gccgaaacga tggatacaat tattagagac attaactgac tcagttagtt    179880
     tcgcagttat tgttcaaatt attctcactt tatctaacat ttcgctaata aataaacaaa    179940
     ccttggggaa gttaaaaaaa ctgaggattc gaattttcga aatactatca aataaaaacg    180000
     atagttggaa atctacatta ctacagaaaa atcttataga atggtacatt tttatgcttt    180060
     ccgtggattg cacaccttta gaattgcaaa acttatatct ccataaggag ttgaaattct    180120
     gtaacggtat cttgaattca ttaacactcc aagtttctga tcctcgctca caaaattacc    180180
     tgcaatttga gaacacgtat aagctttttc aaatacaaaa gtcatctaga attaacaact    180240
     cgttcctttt ttacatagaa ttcaattccg ttacctcaaa taggataatg accatagaaa    180300
     gacacattta tttggaaatt aaggaaggcc agttttgtat ttcaaatgat aactacataa    180360
     tcggtttatt tgaaaacttc gaattcgaag cgggcacttt gtactttatt ggagttttaa    180420
     ttgatcacaa taatcgaata actctttatg ttgatggaag tatgatcaat cagctcacgt    180480
     tatttgaaaa ctctatatgc caattaagca cttgtgaact gggatccatg atttgttcaa    180540
     ttaaagtata tagattttat ttgtgggatg gattattaac agaatttgcg ataaatatac    180600
     ttcaagctat cggcaccaat taccaatata catttagcaa gaaaaaagaa gggcctgaag    180660
     ttttatcgct ctgccaagac tttttgatcg ctaaggctca tttaatggcc aggcctacaa    180720
     cagaaatatc ttccacaaaa tacatcgatg agattgaact tcttgaaatg gaaaatatca    180780
     ttattgatgt taacccaaat gatattcttc aagatttcac cgaatcgtct aattttacgg    180840
     taaaatttga ggaaagcacg aactcgaaaa atattccgga agtgggtaag tgctatttct    180900
     ataggagttc aaacttggtt tcaaaatttg tgtccattga ttctatacgg cttgcgtttt    180960
     taaacatgac agaatccggt agtatagacg atctgtttca tcatgtatca catctgatga    181020
     atcttttacg aaatattgat attcttaatt ggtttaaaaa agactttggc tttcctttat    181080
     ttgcttatac tttaaaacaa aaaataacac aagatttatc tcagcctctg aatatccaat    181140
     ttttcaattt attcttagaa ttttgcgggt gggatttcaa cgatatttcc aaatccataa    181200
     ttctagatac tgatgcctac gaaaacatag tccttaactt ggatttatgg tatatgaatg    181260
     aggatcaaag ttctctggcg tcaggcggat tagaaattat cagatttctt ttcttccaaa    181320
     tttcaagttt gatggaagcc tctatttatt ctaagttcaa ttccaataaa ttcaatgata    181380
     tgaatatcct agaaaaacta tgtttaagct atcaggctgt cacaaaaaga gaaaatcaga    181440
     acagtaaatt taatgagcta tcaagtgatt taatttctgt atttgttact ttattgaaaa    181500
     gcaatactga taaacgacat ctgcagtggt ttttacatct ctcatattac tttattaaga    181560
     gaaaagatgt acgttctaca gagattatac ttcaagcggt agatcaactt ttttcgtttt    181620
     acttagatca aggtagtgac gaaaatgcga agatactttc agagattata ccacttaagc    181680
     taatactgat gattatggat caaatagtgg aaaataatga atcaaaccct attacgtgct    181740
     tgaatatctt atttaaggta gttctgacca ataaaccgct tttcaaacaa ttttacaaaa    181800
     atgatggttt gaaactcata ttgactatgc tttgtaaggt agggaaaagc tatcgagagg    181860
     agattatttc tttgcttctc acatattcta ttggcaatta taccacagct aacgaaatat    181920
     tttcaggtgc tgaagacatg attggaggaa tttcaaacga caagataact gcaaaagaaa    181980
     ttatttattt ggctgtcaac ttcattgagt ggcatgtgat taattctaat gccagtgatt    182040
     cttcttctgt attggacctg aacaaccata tattaagatt cgtcgaagat ctgaaatcgc    182100
     tgagcgctgt tccgattaat gaatctgtat ttgatcctaa aaaaagttat gtgatggttt    182160
     cattattaga tctctcgata gctttgaatg aatcggagga catctcaaag ttcaagagct    182220
     cttcaaaagt gatttcagag ctcattaaag gtaatataat gtgtgctctt acgaaatatg    182280
     ccgcttatga tttcgaagtc tatatgagca catttttttg tcacagtaca gaatacaaac    182340
     tggtttatcc aaaaactgta atgaacaatt ccagttactt agagctatca tttatagtga    182400
     cactcctacc cgaaatactt aatgacctgg tagatagcaa taacaatttg aacctgatga    182460
     tgttgaagca tccatacacg atgtcaaatc tcctttattt tcttcgcaaa tttcgacctg    182520
     atacgtcaca gatagttatg cctaaagatt tttatttctc aagttataca tgtctcttgc    182580
     attgtgttat tcagattgat aaatcatcat tttaccattt caaaaacgtt tctaagtcgc    182640
     aactgttaca ggacttcaaa atctgcataa tgaacttaat atattccaat actctaaagc    182700
     agataatctg ggagaaagaa gaatacgaga tgttttctga gtcactgatg gcgcatcagg    182760
     aagttttatt tgcacatgga gcatgtgata atgagaccgt tggcttattg ttaatatttt    182820
     ttgccaacag attacgtgat tgtggataca acaaagcagt cttcaattgt atgaaagtga    182880
     tcattaagaa caaggaaagg aaactaaagg aggtggcgtg tttttttgac ccagcgaata    182940
     aaagtgaagt actcgaaggt ttaagtaata tcctctcatg caataactct gaaacaatga    183000
     acctcataac tgaacaatac ccattttttt tcaacaatac acaacaggta cggttcataa    183060
     acattgtcac caatatcttg tttaagaaca acaatttttc tccaataagc gttagacaga    183120
     tcaaaaacca agtttacgaa tggaaaaatg caagatcaga atacgtcacc caaaacaata    183180
     aaaagtgcct tattttattt agaaaagaca acacatcctt agattttaaa atcaaaaagt    183240
     ccatatcaag atacacttac aacctcaaaa cggatagaga agaaaatgca gttttctatc    183300
     gaaataattt aaatcttttg atttttcatc tgaaacatac actggagata caatcaaatc    183360
     caaattcgtc ctgcaagtgg tcatcggact ttgcagaaga ttttgatggg atgaaacgga    183420
     ggcttttgcc tgcttgggaa ccaaaatatg aaccactcat taacgaggaa gatgctaatc    183480
     aagatactat aacaggtggt aacagacaaa ggagagaaag tggaagcatt ttatcctacg    183540
     aatttatcga acatatggag actcttgagt cggagccagt tggagatttg aatgagaata    183600
     gaaaaattct tagacttttg aaggataacg attccattgc aactatttgg aattgcagtt    183660
     tgattattgg attagaaatt aaggagggga ttttaattca tggcagtaat tacctttact    183720
     ttgtaagtga ttactatttt agtttagagg ataaaaagat tctaaaatta tcagaagtat    183780
     cgcaagaatc acgggatatg acggttagct taattaacgg ccctgatgtt aaaagggtat    183840
     caactttcct aaagcacgaa gtctttgttt ggaaacttct cgatatcact ttcgttacca    183900
     aacgaccctt tctacttcgg gatgtcgcca tcgaattatt gttcaaagag agagttagcg    183960
     ctttttttag tttttacaac aaaagagtga gagatgacgt tttacgggta ctgaataaga    184020
     tcccgaagca ccttccagca gatccaattt tttcaagcgt tttacaagaa ataaacgacc    184080
     gaggaaatag tatagtggca agaaatggaa taggaaaggc aagcattgct tctaaattca    184140
     ctagcgtctt ctcagcgaac aacagcctaa tagatggatt tgagatcagc aaaaaatggg    184200
     ttaggggaga gatttctaat ttttattacc tgttgagtat caacatccta gcgggaaggt    184260
     cattcaacga tttgacccaa tatccagtgt ttccgtgggt tattgcagat tacgaaagta    184320
     acgtactcga tttagagaat cctaaaactt accgggacct atcgaaacct atgggcgctc    184380
     aaagtgagaa aaggaaatta cagtttatag agcgttatga agctttggct tccctggaaa    184440
     atgctgattc cgcaccattt cattatggca cgcattattc ctcagctatg atagtatctt    184500
     catatctgat aaggctgaag ccctttgtcg aatccttttt gttattgcaa ggcggaagtt    184560
     ttggccctgc agatcgttta tttagttcgc ttgaaagggc ctggagctct gcttcttctg    184620
     aaaatacaac ggatgtcagg gaattgacac ctgaattttt ttttctacct gaatttttga    184680
     tcaacgttaa tagttatgac tttggtacag accaaagcgg taaaaaagtt gacgacgtcg    184740
     tacttccacc ctgggcaaat ggtgacccaa aggttttcat tcaaaagaat agagaagctt    184800
     tagaaagtcc ttatgtatca gcacatttac atgaatggat tgatttgata tttggttaca    184860
     aacaaaaggg ggacattgct gtgaaatctg ttaacgtatt caacagattg agttacccag    184920
     gcgctgtaaa tctagataac attgacgatg aaaatgagcg cagagctatc acaggcatta    184980
     ttcacaactt tggtcaaacg cctttacaaa tatttcagga acctcatccg gaaaaaatag    185040
     cctgcaatgt tcaacagcta acaacagagg tatggcgtaa ggttccaatg aagccaatat    185100
     ttgagaagac aatctttaat ttgaatgaaa agaacaggtc cgtcgattat gttatacacg    185160
     atcctagtta cttcgattca ttatactgga ggggcttcgc tttcccaaac ttgtttttca    185220
     gaacggaaga atcgttagtg tcattgagaa ttgtgcataa aaattggtta aaaattggac    185280
     tagatatttt taaaaagacg catatggctc agattacatc gtttgcgtac tggaagttgg    185340
     gcgaattcat aactggcgat aaaaatgggc tgataaaagt ttggaaatat cgtaaagata    185400
     agcattcggt ttcaggtaac cttgagaaca aaaaaacaat gtttgggcac ctatgcgagc    185460
     taaaggagat gcgctgttat cacgactaca atacgctttt aaccttagac atcagcggct    185520
     tagtatatgt ctgggacatg attaatttcg aactagtaag gcaaataaca aatgatgcgc    185580
     aaaaggtcgc aatatctcaa catgcaggga gcattatggt attgactaag aataacgcca    185640
     tttcgatctt caatctaaat ggacaaatat atacatcaaa gaaattcgaa ccagctaaaa    185700
     ttgtaagctc aattgatttt tttgacttca ctaagttaga cgcaggttac agaaagcata    185760
     tctattggaa agagatggaa atactactag tgggctttga agatggaact atagaaattt    185820
     acgagctctt tttgaatttt cataatgaat gggcgataaa gctactgaag cagctctgta    185880
     ccgaaaaagg gaaagccata actagcatta agggacaggg gaagacatac ctgtcccaga    185940
     aaagacgcaa ggatacagca gagcctcatg agatagaagt gattgcggga acattagatg    186000
     gcagattagc tatttggtac taggcatcac atcgtaacgc ctttctttaa atgattcaat    186060
     ttttgtagtt tatatcttta cttttgaaac tgatttctca tcccatctag tattgtaatt    186120
     gcgtacgtat ccaatatcat taccaacgcc gggtattttt ttctagtatt tcttctccat    186180
     ttcgcctatg gaaaacggca aaagggtaaa agaaaaaaac aaacgattaa ttcttctttg    186240
     aattatgtaa aaatcaaaac gcaaccgcag atttaataga gaccagaaat tcggattact    186300
     attgactttg tgcaccacct tcaaatttac tcattgttta agacaggcag tgggaaagaa    186360
     gccgtcatat tgctcgaatc cttaacaagc aaaatataca accactaaat tattccgaaa    186420
     gggcctgctt aataatttgc ctactaactt gtgcatagaa cagcaaacag aaacaaagcg    186480
     taagaaacat ggggtatccg ccacctacac gaaggcttgg agataagaaa aggtaccatt    186540
     attccaataa tcctaaccga aggcatcctt ccgctgttta ttccaagaat agctttccaa    186600
     aatcaagcaa taatggattt gtatcttctc ctactgccga taattcaaca aatccgtctg    186660
     taactcccag tactgcatct gtacctcttc ctacagcggc acctggaagc acgtttggta    186720
     tcgaagcacc caggccatct cgatatgatc cgagctcagt cagtaggcct tcgtcatcat    186780
     cttattcgtc aacaagaaaa attggaagcc gttataaccc agatgtggaa agatcctctt    186840
     caaccactag ttcaactccg gaaagtatga atacgagcac cataacacac accaatacgg    186900
     atatcggaaa ctcacgctat tctcgaaaaa ccatgagcag atataatcct caatctacta    186960
     gttctacaaa cgttacccac tttccctcgg cattatcaaa cgctccaccg ttttatgttg    187020
     ccaacgggag ttctcggaga cctcgatcaa tggatgatta tagtcctgat gtaacgaaca    187080
     agctcgaaac aaataatgtt tcatctgtta ataataacag ccctcattct tattactcta    187140
     ggagcaacaa atggagatcc attggaacgc cttccagacc accatttgat aatcatgtcg    187200
     gcaatatgac gaccaccagc aatactaact cgatccatca aagggaacct ttttggaaag    187260
     caaatagtac tactatttta aaatcaactc attcacagtc atcgccttcc cttcatacta    187320
     aaaaatttca cgatgcgaat aaattggaca aaccagaggc ttcagttaaa gttgaaacac    187380
     ccagtaaaga tgagacaaaa gccatatcgt accatgataa caattttcca ccaagaaaat    187440
     cagtttctaa acctaatgca cctttagaac ccgataatat caaggttggc gaagaagatg    187500
     cattggggaa aaaagaagta cataaaagtg ggcgtgagat agcaaaggaa catcctactc    187560
     ctgtaaaaat gaaagagcat gatgaactag aagctcgcgc taaaaaagta agtaaaatca    187620
     atattgatgg aaagcaggac gaaatttgga cgacggcaaa aacagtggcc agtgcagtcg    187680
     aagtttccaa agaaagtcaa aaggaactaa cacgctctgt tgaaaggaag gaaagcccag    187740
     aaattagaga ttatgaaaga gcatacgatc cgaaagccct gaaaacagac gtaacaaagt    187800
     tgacagtaga caatgataat aaaagttacg aagaacctct tgaaaaagtg gaggggtgta    187860
     ttttcccatt accaaaagca gaaacgagat tatgggaatt gaaaaaccag aaaagaaaca    187920
     aaataataag tgaacaaaag tacttactga aaaaggcaat taggaatttc tcagagtatc    187980
     ctttttacgc acagaacaaa cttatacatc agcaggctac cggacttatc ttgacgaaaa    188040
     ttatatcaaa gataaaaaag gaagaacatt tgaaaaaaat aaatttaaaa catgattatt    188100
     tcgatctcca gaagaagtat gaaaaagaat gcgaaatttt gactaaactg agtgaaaatt    188160
     taaggaagga agaaatcgaa aataaacgta aagagcacga actaatggag cagaaaagac    188220
     gtgaagaagg tatcgaaaca gaaaaggaaa aaagcttacg gcatccatcc tcgtcttcct    188280
     catctcgtcg cagaaatagg gctgacttcg ttgatgatgc ggaaatggaa aatgtattgc    188340
     tacaaatcga cccaaattat aaacattatc aggctgctgc aacaattcct ccgctaattt    188400
     tagatccaat ccgcaaacac tcttacaaat tctgtgatgt aaataacttg gttacagaca    188460
     aaaagctttg ggcgtctaga atattgaaag acgcctctga caactttact gaccatgagc    188520
     actctttatt tttggagggt tatttaattc atcctaaaaa atttggtaaa atttctcact    188580
     acatgggcgg cttaagaagt cctgaagagt gtgtcctaca ttattataga acaaagaaaa    188640
     ctgtgaatta taaacaactt cttatcgata agaacaagaa aagaaaaatg tcagccgctg    188700
     ccaagcgccg caagaggaag gaaagaagta atgacgagga agtcgaagtt gatgagagta    188760
     aagaagagtc aacgaacacg atagagaagg aagaaaaaag tgagaacaat gccgaggaaa    188820
     atgttcagcc ggttctagtt caaggttctg aagtgaaagg tgatccatta ggtacaccgg    188880
     aaaaagttga aaatatgatt gaacagagag gcgaagagtt tgcaggtgaa ttggaaaatg    188940
     ctgagagggt aaacgactta aaaagggcgc atgatgaagt tggagaagag agcaataagt    189000
     ccagtgtaat agaaaccaac aatggggtac aaataatgga tccaaaagga gctgttcaga    189060
     atggttatta tccagaggag accaaagaac ttgacttcag tttagagaat gcgttacaga    189120
     gaaagaaaca caaatctgca ccagagcata aaacaagtta ttggagtgtt cgtgaatctc    189180
     aactctttcc agaattgttg aaggagtttg gctctcaatg gtctctcata tcagaaaaac    189240
     tgggtaccaa atctactaca atggtaagga attactacca aagaaatgca gctcgcaatg    189300
     gatggaaatt actggttgat gaaaccgact taaagcgaga tgggactagt tcagaatctg    189360
     tacaacaatc tcaaattttg atacaaccag aacgaccaaa catcaatgcc tatagtaata    189420
     ttcctcctca acaaagaccg gctttgggtt attttgttgg acaaccaact catgggcata    189480
     atacatctat ttcatctatc gatggctcta taagaccatt tgggcctgat tttcatcgtg    189540
     ataccttttc taaaattagt gctcctttaa ccactttacc accaccaaga ctaccatcta    189600
     ttcagtttcc tcgttcagaa atggcagaac ctacagtgac agatttgcgt aacaggccct    189660
     tagaccatat tgacacgttg gctgatgcag cttcgtcagt aacaaataat caaaacttca    189720
     gtaatgaaag gaatgcaatt gacattggcc gtaaatcgac gacaatcagc aatctattga    189780
     ataattcgga tcgaagcatg aaatcttctt tccaaagcgc ttcaagacac gaagcacagc    189840
     tcgaagacac tcccagcatg aacaatattg tagtacaaga aataaaaccg aatattacta    189900
     cgccaagatc gagttctatt tctgcattac taaatcctgt aaatgggaat gggcaatcaa    189960
     acccagatgg aaggccgttg ctgccatttc agcatgctat ttctcaaggc actcctactt    190020
     tccctttacc ggcccctcgc actagtccaa taagtcgtgc gcctccaaag ttcaattttt    190080
     cgaatgatcc gttggcagct ttggctgcgg ttgcctccgc gccagatgca atgagcagtt    190140
     ttttatctaa aaaggaaaat aataattgaa caaacggctg agacgggcaa tacatatgct    190200
     ctacttcttt tccatccaat ggttggtgaa actctcgagc atacattacc ttacgtgtgt    190260
     tagtgtacta tattatatat atatatatgt atatatataa agggaggagt ttttaattat    190320
     aattgtaatt tcgtattttt tctgcattat acagtttttt ccgattttaa acgactttat    190380
     ttaagtgtcg tgtaaatatg tcacatttta tttttgtacg tattcacatg tcctggcgtg    190440
     cggccattgc tgaaaatcgc aaaacccaca gagaaataaa catcgcgaaa aagtcaatga    190500
     aaaattggaa aatatttttc atttcactat tatccacaag caattttgta caaagtgaaa    190560
     aggttgaact aattatcttc gtctagaagc catgaattca ctcgttactc aatatgctgc    190620
     tccgttgttc gagcgttatc cccaacttca tgactattta ccaactttgg agcgaccatt    190680
     ttttaatatt tcgttgtggg aacatttcga tgatgtcgtc actcgtgtaa ctaacggtag    190740
     atttgttcca agcgaattcc aattcattgc aggtgaatta ccattaagca ctttgccccc    190800
     tgtgctatac gccatcactg cctattacgt tattattttt ggtggcaggt ttttgttaag    190860
     taagtcgaaa ccatttaaat taaatggcct tttccaattg cataatttgg ttttaacttc    190920
     actttcattg acgcttttat tgcttatggt tgaacaatta gtgccaatta ttgttcagca    190980
     cgggttatac ttcgctatct gtaatattgg tgcttggact caaccgctcg ttacattata    191040
     ttacatgaat tacattgtca agtttattga atttatagac acctttttct tggtgctaaa    191100
     acataaaaaa ttgacatttt tgcatactta tcaccatggc gctactgcct tattatgtta    191160
     cacccaattg atgggcacca catctatttc ttgggtccct atttcattga accttggtgt    191220
     tcacgtggtt atgtattggt actatttctt ggctgccaga ggcatcaggg tctggtggaa    191280
     ggaatgggtt accagatttc aaattatcca atttgttttg gatatcggtt tcatatattt    191340
     tgctgtctac caaaaagcag ttcacttgta tttcccaatt ttgccacatt gtggtgactg    191400
     tgtgggttca acaactgcca cctttgcagg ttgtgccatt atttcttcat atttggtact    191460
     atttatttca ttttacatta acgtttataa acgtaaaggc accaaaacca gtagagtggt    191520
     aaagcgtgcc cacggcggtg ttgccgcaaa ggttaatgag tatgttaacg ttgacttgaa    191580
     aaacgttcct actccatctc catcaccaaa acctcaacac agaagaaaaa ggtaagtgta    191640
     aaatctttga aagaatttaa gtattcaact ttcgtatatt cgttttttct tagtggatct    191700
     attgttacta ttatcactat tattatattg taaaagaccg gatggttttg ttatatatta    191760
     catacacatg ttatcgttga aaaaagtttt ccgtttcctt tcgacagtca tcagataatt    191820
     ttatccgagt cttttatatg ttaaatcttg ttgacaaatc gtccgctcta accctagata    191880
     acaacaatga tctttttatc atttctggcg ttattttagc gcctcctccc actaatgtta    191940
     attgcttata gttacctgaa ggagcagcga ggatggagat cgtactgtgt atacttgttt    192000
     cttccgcttc agtatctagg tctgctatta gcacagtgtt caatttatcc atatcaatgt    192060
     ccacttcctc ttcttcagag ttatcagagt tttgtaattg gcattcgggg tctaactcca    192120
     ctatcccata atttgaagca aatgcaatat tctttgcgtt tatcattaac ggtactgact    192180
     tagtttggtc gcaaataatt tcatacgttt ctcttatggt ggcacttctt cctcttgttc    192240
     ttatagtcat tcttaaatcg gacgcacgct catctataaa tgctctaggt aactttacgc    192300
     tctgtaaagc gtacatcaaa gaattccaac acaaatcgaa gactggacca gtgcgactca    192360
     agactacaat tttcgcatac aaaacgtatg accattttct tttcattttc aggtttgttt    192420
     cattcagcgt atcatcttct aattcatcgg gatacaagac ggaaaacgta ccgtcttcat    192480
     tcgcactacg aacaccagct tttaccttca aggctttttt aggcaatatc ctagagtgca    192540
     atatggaatc gtgtagtttt tgtgatatag tcatttcttc atcggtgcaa gcgcccactc    192600
     tacctctttc aacttccacc accggataga cagaagcata atttgcaatt atgtcctcct    192660
     ctttggtcac ttcgaacaat tcttcctcac cgaaatcatc caaatcttta atcgcggcgc    192720
     tagtttcttc tattattcca cccgtaatag aagttatgac tatggttttc ccacttttca    192780
     aaacatttga gcctaaaatg ttgtttttag tgtctatatt accagcatcc gcataacgcg    192840
     ataaagtatt attttctata gcaacatctc taaattcttc atattttctt agacatggcc    192900
     tgattcctag ggataagtgt ctttgtaaag acaattctgg agatattctc gcaagaactt    192960
     caggtggaaa agtaattggg tgtatctcaa tagtttctaa cgtggtactt tcagccattt    193020
     ccaatattag atgcctgtga aactactgtc aaacttattt gtgtaacaat actcatcgtc    193080
     taatttgtcc attattgtta tatactctgt cataaaaaaa gaaagaaaaa tcttatactt    193140
     tcgtcgactg tgatttgaaa atctctccag atcaaacggg aataaaaggg tttatatccg    193200
     aaggtggcca gaacaatcat gaagcaaata ggataaaaat agccaataag atgtttgttg    193260
     tctttcatcc caaagttcca acagcatatt tcaaagatgg gtattacagt aataggttct    193320
     ctaaactatg atttggacac atttacggat agattaccta acgctggaga aactttcagg    193380
     gctaaccact tcgaaacaca tgctggtggt aagggattga accaagctgc ggccattggt    193440
     aaattaaaaa accccagcag cagatatagt gttcgaatga ttggtaatgt tggaaatgat    193500
     acatttggta aacaattgaa ggacacttta tccgattgcg gagtcgatat cactcacgtc    193560
     ggtacttacg aaggcattaa tacgggtacc gctaccatac taattgaaga gaaagctggt    193620
     ggccaaaata ggatattgat tgtagaaggt gctaacagca agactattta tgacccgaaa    193680
     cagttgtgtg aaatttttcc agagggcaag gaggaagaag agtatgttgt ttttcaacac    193740
     gaaattcctg atcctctttc cattattaaa tggatacatg cgaacaggcc gaattttcag    193800
     atcgtatata acccctcacc tttcaaggcc atgcctaaga aagattggga gttggtagac    193860
     cttttggtcg ttaatgaaat tgagggtctt caaatcgtgg aaagtgtatt tgataatgaa    193920
     cttgttgaag aaataaggga gaagataaag gacgactttt taggagaata tcgtaaaatt    193980
     tgtgagcttt tgtatgaaaa actcatgaat cgaaagaaaa gaggaattgt ggttatgact    194040
     ttgggttcga gaggggtgct tttctgttcg cacgaaagcc ctgaagtaca attccttccg    194100
     gctattcaaa atgtttcggt tgttgatact acaggagctg gagatacttt cctgggcggt    194160
     ttggttactc aattgtatca aggagagacc ttgtctacgg ctataaagtt ctctacatta    194220
     gctagttcat tgaccattca aagaaaaggt gctgctgaaa gcatgccact gtataaagat    194280
     gttcagaaag atgcataaaa tctactgcaa ttttttactt ttagtttgtt aaattttagt    194340
     tttcgtcata tatataaagt ttaaaaaggt acaaagaatg cagtaataag aaatgtaatt    194400
     acatgagggc agtttaagtg ctacctttta agacggaaga actaatacca taaccgagag    194460
     taattacgca gacaaacgct aacaacgaag caggaacacc tctggagata aaagcgccta    194520
     cagttagcca tctattaccc tttttatcgg tcatagaaat agcagtaacg tttggaaatc    194580
     cagatgaagc caaccccata ccgcatgagg ctaacaaggc gcaaccgaac acaagaattg    194640
     gagctgcctt tggatcggat aatttgtcac caacttcttg caccaaggga ataatgatga    194700
     ttgctgacac agtatgtgag acaaaagtgc ccacaactaa cattaaaata ccgaaaatac    194760
     ataagatagc aaaaacacca tcgttctgaa ttttcttttg taatgctctt gcaatagtta    194820
     ccaacaagcc tgaagatgaa actgccttac caagggctat accacccata gcaagaacaa    194880
     caattgacca agggaatgtg ttgaaatcct ttgttgatag tagacctgta ccaaaaaaca    194940
     ggactatcgg tattactgca atttcaccgg acgatccaaa agcactttct atttgtgact    195000
     ctacacacca tagaagaata gtagcaatag ttacaatgat gataaaatat tgctttatag    195060
     taaatctggt ccttattggt ttaaattttt ccagtttagt tttgcctatt ttaaaggtga    195120
     gtatcatcaa ggcccaggag cacagcatcg atagaatacc tgtaggcaga gcgacagcaa    195180
     aaaattgccc ccagccgatt ccataaggtt ttaagtactg catggagatg atattctgtg    195240
     gcgaagaaat aggtgaagcc ataccaccaa tatctgccga aagtgcaaca cccatgacta    195300
     atgccttagc aaacggtgaa gtgtagtcca gcggatctag taagggtgtt aatagagaat    195360
     atgtcaatac tggggaggca acgttggaaa tccacatcga aagaaagaat acaacactca    195420
     ttgccattaa aaggacattt cttggcttgg tacctgcaag ggccaataac cacgatgcca    195480
     aaactttcgc aacgttatat tgcgacaagg cttcacccaa tgtgaaacct gctaataaaa    195540
     tcataattgt tgacgaccac attgtaccta agatttctgt agaggcagct gctgctccca    195600
     ttaccttacc gtcatcgtct tttagtaccc taaaaaggac agttagaagg ggaaccaata    195660
     aacctgtgat gtgtaatgga atggcttcac tagcccataa gaaagcacag cattctacca    195720
     atgccataca ccggtgttcg acagggtcat tgaaagtttt aacacccaac aaaacacctg    195780
     tgacaatgat aatgaagcct attttcattg ctcttttccc aaaaaatagc ttaggaactg    195840
     ccaaattttc aattttagta aacttcaaat taattggctt aggcaatgga tacttgaaat    195900
     attcaatttg aagcttttct tgcataagtt tctcagcttc atcttcaata gttattatat    195960
     cgttattttg cgaagagagg cccaacatgt ctttccatgt gttgcttctt tcccaaacaa    196020
     tgtggtcgtg caggtacgac tttaactctt gcttgcatga atctacgttc ccaggctgac    196080
     ccatgagaac agcataaaat tcaataagtt gtgcaatttt actgtttaaa ctgcttaaag    196140
     tttcatgctg gaagatgtag gtgtctttga aaaattcttc actttctatt aattcttgcc    196200
     tagtgttcat gtgcaatact ttatcagact tcttagtaat tttactgaaa cccattctgt    196260
     tcaattcgat aaaagatttc aactggcaaa ggtctatgta aagatttatt attgtctgtt    196320
     ttaataatga ctttttctga gatttaatgt taaattgcga ataattcaag agggcggtat    196380
     tgtcggtagt gtcagcaaac acgtcaacgt catcatcttc atccatttct tcttcgctgt    196440
     aatcaaacct atttctcaat tcactgtcga tgtttgaaga gtgtatttca aatgggttat    196500
     tagatgaatg tgtctctgat gtaccagaaa taatttctct taaaggaggc aatgcttgaa    196560
     tttcaggatt gaaagtttca ttcaatcttg ttacaatgcc ttccttctcc aaatcattaa    196620
     tcaagtggtc aaatctttca tagaacttag cttccattct tttgtagaaa tcatctactt    196680
     tcaatttctc gtcgctcagg ttagttacga atgtatcata agaactgaag agcgtctttc    196740
     cctcgctact cacagatgag ctgcgtgatt caaagaattt cttacgtata aaattcttat    196800
     tgaaagaggt ggttttccct tgaggagata actcgtctaa ctcaattgtt tcctcgttaa    196860
     tattgttccc atctatggcc ttttcgtcgg agtctcccct tttgcttcct gaaggtgttt    196920
     tagaaccaaa gagcttacgc ttgagtttat gtgtaaatct tcttttcgat gaagatggtt    196980
     ctcctgcagc tatgttgctt tctatatcag cgattggacc tggagtctga gagtcagcgt    197040
     catcgtttaa gtcaccggtt ggcgtttctt gtttcaattc atctgtctgt aatgtgtaga    197100
     tcaaattttt caattcgtta taatctaggt aatgattctg ccattcaggg acagcgttgt    197160
     atttgagaaa gtgtgagaat ctcatttcga ggcacaataa tagccgcctt taccgtagtt    197220
     ttgctgcacc tttatctgag agctgactgc ttttttggtg tgaaacactg ttttctggta    197280
     ataatttttc aatgcatcgg attacttttc ccacgtgcga aatcatcaat taattagatt    197340
     gaaaaaaggg taagggaaaa taagaaagag gcggtagcct aaagatacgg taattgaaac    197400
     gtttcctatg cacaatctta aaccttttta ggtaattgat taagttgact gtaatatctg    197460
     taaaagatta catctaattt acgtctggtt tcttatcaaa aaatattatc tactgtagtt    197520
     atgcaagtat tcttaatttt cagtactaaa catgaatatt aattatttgt gagcgtacaa    197580
     gaagcaaaag gaagtcatct ttctttgaac agttctgttt ttaggtaagc cttggaacct    197640
     tagctatact gacttgatac gccctgtctt tgttgtcgtt atataaagtg tgcaccttta    197700
     tcatagcccc taataagctt cttgcagtag tatttgaaca gtgtatatct tcatattgct    197760
     tttgttgtaa atattgcgca aaagcgacta tctttgtgat ttggttgaac ttttgcatat    197820
     tcacgttatt accatcttta gtgaatgtat cgtttccgtc tcttatgaag gtaatgtccc    197880
     tgataagcag tgatgtaaaa ggtacacaag gaagctgact gtggaaaata tgtttaattg    197940
     ttcttctata aacgttgtag ttgttgtttg gatgtacgac gacttttagg cgctgaaaaa    198000
     ggtggtctga tttaacatct atcgggagag atagtctttc tattgaatga ttttgcaatg    198060
     atgtaatgat tgaagcaagt gagtttaagt ttcgtaagta tagacaagac agtgcaactt    198120
     gtaaccagta ggaaatggtg tgcgtttgct gcaaagttgt ctcaagaacg taggacgata    198180
     actggttgga aagcgtaaac acggagtcaa ttgttgtatc gttgtgtttg aaatgtcttg    198240
     tgaattctat tgtttcaata tccaagtaaa gagaagattc taagagagtc aatgtctttg    198300
     caagtgacca tggagatacg tttagagcga aggcttcgac ttctagaagt tcaccctgtt    198360
     tccattggaa aagtaaatca ctgaggtcag ttgcaccgca caattcatca tttgcgttcg    198420
     ttttgtctat ctcgtattgg agaaataagt tttcgtagtc caggggcggt ttattttctt    198480
     cgatttcctt atcagttaga ccaatgtaat gaatcttcaa ttgcctcgtt ctttttttgt    198540
     ttataaacag ctgaactatg tctgcaaaca gttcttggta ttcataatat tcagccaagt    198600
     gactgtacca aaaattgagg atatctttta atgttgtctc actatcttgc caataagact    198660
     ctacccagat ttgtattaga cgagggacgg agtgattttt gtgtttgttt ttattaattg    198720
     tgggatagga tagtagcaac tcttggagga gagcattgtc agttgtccag tctctgaagt    198780
     taagtagtaa gtttgcggag tcaaaggggg atggcttttg ccatttgtga gagttgtgcg    198840
     gcagcatctt attcaaatag agctgtattc tgaagacctc ttgtagaaca tcatccatac    198900
     taaaaagtaa atcgtcctgt cccattacga gctgtattag tgctgtgacc ctctgtatat    198960
     ttacgttgcc atgaagaagg taatgggcga tattttgata caattcctga gttgcatgtt    199020
     ggattgagtt tacgaagggt cgccagacgg ccagaaacct ccaggcggag ttaacaacta    199080
     gtaatacggc atccatgttt gcatcagcgc cgagcctata ccagtcactg agtagacgtt    199140
     ttcttgctct ttttatgtcc tgacttcttt tgacgagggg gcattctcta gagacacagg    199200
     cagttgcttc cagcaactgc cgtacggccg ttctcatgct gtcgaggatt ttttttggga    199260
     cgatattgtc attatagggc agtgtgtgac ttatgaattg ttgtagaagg acgtctgtga    199320
     tgttggagat atgtattttg ttaactcttc ttgagacgat ttggccctgg atagcgaagc    199380
     gtgcggttac aaataggtcg tcttgttcaa gaaggtaggc gaggacatta tctatcagta    199440
     caaacatctt agtagtgtct gaggagaggg ttgattgttt atgtattttt gcgaaatata    199500
     tatatatata ttctacacag atatatacat atttgttttt cgggctcatt ctttcttctt    199560
     tgccagaggc tcaccgctca agaggtccgc taattctgga gcgattgtta ttgttttttc    199620
     ttttcttctt ctattcgaaa cccagttttt gatttgaatg cgagataaac tggtattctt    199680
     cattagattc tctaggccct tggtatctag atatgggttc tcgatgttct ttgcaaacca    199740
     actttctagt attcggacat tttcttttgt aaaccggtgt cctctgtaag gtttagtact    199800
     tttgtttatc atatcttgag ttaccacatt aaataccaac ccatccgccg atttattttt    199860
     ctgtgtaagt tgataattac ttctatcgtt ttctatgctg cgcatttctt tgagtaatac    199920
     agtaatggta gtagtgagtt gagatgttgt ttgcaacaac ttcttctcct catcactaat    199980
     cttacggttt ttgttggccc tagataagaa tcctaatata tcccttaatt caacttcttc    200040
     ttctgttgtt acactctctg gtaacttagg taaattacag caaatagaaa agagcttttt    200100
     atttatgtct agtatgctgg atttaaactc atctgtgatt tgtggattta aaaggtcttt    200160
     aatgggtatt ttattcattt tttcttgctt atcttccttt ttttcttgcc cacttctaag    200220
     ctgatttcaa tctctccttt atatatattt ttaagttcca acattttatg tttcaaaaca    200280
     ttaatgatgt ctgggttttg tttgggatgc aatttattgc ttcccaatgt agaaaagtac    200340
     atcatatgaa acaacttaaa ctcttaacta cttcttttaa ccttcacttt ttatgaaatg    200400
     tatcaaccat atataataac ttaatagacg acattcacaa tatgtttact tcgaagcctg    200460
     ctttcaaaat taagaacaaa gcatccaaat catacagaaa cacagcggtt tcaaaaaagc    200520
     tgaaagaaaa acgtctagct gagcatgtga ggccaagctg cttcaatatt attcgaccac    200580
     tcaagaaaga tatccagatt cctgttcctt cctctcgatt tttaaataaa atccaaattc    200640
     acaggatagc gtctggaagt caaaatactc agtttcgaca gttcaataag acatctataa    200700
     aatcttcaaa gaaatattta aactcattta tggcttttag agcatattac tcacagtttg    200760
     gctccggtgt aaaacaaaat gtcttgtctt ctctgctcgc tgaagaatgg cacgcggaca    200820
     aaatgcagca cggaatatgg gactacttcg cgcaacagta taattttata aaccctggtt    200880
     ttggttttgt agagtggttg acgaataatt atgctgaagt acgtggtgac ggatattggg    200940
     aagatgtgtt tgtacatttg gccttataga gtgtggtcgt ggcggaggtt gtttatcttt    201000
     cgagtactga atgttgtcag tatagctatc ctatttgaaa ctccccatcg tcttgctctt    201060
     gttcccaatg tttgtttata cactcatatg gctataccct tatctacttg cctcttttgt    201120
     ttatgtctat gtatttgtat aaaatatgat attactcaga ctcaagcaaa caatcaattc    201180
     ttagcatcat tctttgttct tatcttaacc ataaacgatc ttgatgtgac ttttgtaatt    201240
     tgaacgaatt ggctatacgg gacggatgac aaatgcacca ttactctagg ttgttgttgg    201300
     atcttaacaa accgtaaagg taaactgccc atgcggttca catgactttt gactttcctt    201360
     tgtttgctag ttaccttcgg cttcacaatt tgtttttcca cttttctaac aggtttatca    201420
     cctttcaaac ttatctttat cttattcgcc ttcttgggtg cctccacagt agaggttact    201480
     tcctttttaa tatgtacttt taggatactt tcacgcttta taacaatatc aagtttacct    201540
     tcttcattac tattcatctt cgccacaagt cttctctccc ttggtgtttc caatctaact    201600
     acaaaactgt tgattagggt gtacatcacc ctaacaagat catgtatttg cttcctctgg    201660
     tacaagctaa gaacaggtaa attcaaaaca tcccagagta atatcttcaa agggctatac    201720
     cctttaaaca tatctcggca tatttgtatt aacccactaa tattttgacg gccaatcttt    201780
     tctattttta ttttcatatc atcgacgtaa tgaccactta aaaacaactc aatatcatcc    201840
     tcacttttta tatttttaac ttcattgtgc acagattgga cggaggactt aatatcgtca    201900
     cttatggtat ccaaactacc atccataaca actagattta cacattcaga aagcacatca    201960
     acacttttat ccctaatata agaatcctca tggaagcaaa gtatttcagt aaacaaaaca    202020
     agggcatcct tgttttttaa accaccttct aaaagcatga ttttcaaaac cattaaaaac    202080
     tcattctgaa agctttccct ggaaatatct ccgttattta tacctaatgt taatgtatgc    202140
     attatcattc ctgtcaattc cgtaaagtca taagcaccca ctttatgcaa tttgtactta    202200
     gcatacatga tagtagtctt aatcaaagac tcgtatgatg aaagccaatt caccaaattt    202260
     tcgtacctca ataactgagt cttaactttt tccatatatg ctttatcttt atactcattt    202320
     aaagcaactt taacaacatt ttcaatcaag ctgcggacgt acgcatcatc actgtattta    202380
     ttttcaccat tctcattata aacaagaata tccagtaaaa attgcttcac caattttgga    202440
     catttaccat tttcattttt cactttagcc aaatatttgg gaatattaca ctgtaagaaa    202500
     tacaacttag gattctcaaa gttattactc tttggaatat tagagtcttc taggcaaaac    202560
     aaaatctgaa aaatctgaat taaatgctta acaccgccag taaaatccgg atcatatacg    202620
     tatttactaa gcgcttcgca cgccgcgagt cttatgccaa aaaagtaacg ctcgtcgatc    202680
     gccgttctaa acaaaatact tgaataaaca agtgatttca caccaccatt aacaacgacg    202740
     tcctcataat atcgtatggc ttctagttgg gcctctatgt ccccatcttg tctcaactga    202800
     gaagaaaaca tgtaatccgg ctgattaatg tgcatttggc aaatccattc cagatcagag    202860
     tctatgcgta tccactcaaa tgcttcgttt tgcttaagca attcattact ctcagacgta    202920
     cgattaaatt ccgtcaaact gaatcgggaa cactcttcgg gcgacatgta tacatttcct    202980
     agacaattca catccacaac aataggcttc tcctcattat tgttttcaac accattttca    203040
     tcatttgcac caccacctct tttccttaat cttctgtact ttgtattgta ctgaatatct    203100
     atttttgtga atgtatcttt gatttccaca atatgctcat acggagtacc atcgtgttca    203160
     tggatcctta tagtcatcga gcccgtgaag cattcggttc ggttcaaatc tggatgttct    203220
     aagtggtcta gtgcactttt gaaaaatcct tcctccccta ccactttttc gtggccaagt    203280
     tcttcatctt gaacttgcct tatacccagt tctataacca tcctcttcct attaaatctt    203340
     tgggtgacac gtaatatggg taccccagac ccatataccc attcgttgaa aaaattctct    203400
     aatttacttt tattaactct ttcgcaaaca tgttgaaaat gcgatgaagt caacgaatta    203460
     ttcggtaaat caccagacat agcttgaagg aaaattttag gtaatactcg agacataccg    203520
     aaagatcgtt ctgttttagt catccttctg tcaagtatgt gtagtatcat cggtgccttc    203580
     aattgtataa aggacaaatc tttagaagac caagatattg gcctagaact gccggtaaaa    203640
     gtgctcccaa taggcggttt ctcgaagtct tgttccacaa tcgcctcact attacgcttt    203700
     aattgatatt tatacgtgtt attacccatt aattttttgg ttacctgaaa caccatataa    203760
     ccagcaatac caagacagca ccagtagtcg ttcatatcta aaggagttat attcacacaa    203820
     gaccattggt tagcaagtgc ccatgctaac tcattcgtag tactgaatgc tttatcaata    203880
     acttctagag ggtacaataa tctggtatta caaatgccta atgctgcaaa atccatatgc    203940
     ttagaaggtg cggtaggtaa aaacaccata gagtaacaag tgaaaggata agacccaaat    204000
     tctttcgagt agaaatctat aattttttgg cagacaactg tcgaatttat aactgttaac    204060
     tcatctgttt cctgcgtcgg aagtgtgaaa atttgaatgg gtataatatc cgaaccaatg    204120
     tcgtcatcca tagtatcgtt aacattgtcc acaacattct ctctcaactt gtcttcctct    204180
     acttcgtcct cggcatcaac acttggaggt gatatcaaag gtaaagacca tgaattaaag    204240
     gcgcctatag cccaaccaat gtgatgtgga gccacaggat taattatctg aaatatgcat    204300
     ttttttttcg tcaaatcaat cgggtgcgga agttctttaa tatttgaata ttctgaacaa    204360
     cacacaatca catccctcaa actcggattg ttgctttcct caatattccg cctttcctct    204420
     tccccttcct cttcctcttc gtcactttcg ccttcctctt cttcttcatc attatcttgt    204480
     gcatctttgc ttttactatt tttgccttct tcgtcatttt tcaagttaga atccttatct    204540
     tcgtctttga taactcttgc cggcttcccc tcttcctctt catcgtgctc aggcgtatcc    204600
     tccttctctt tttcactctc ttctccattt tgtccgatta atttcgaagt acctatattt    204660
     ttaaccaatc tcggtacgct gaattctaac tcccatgtag atttttcatc aagcaaatcg    204720
     acacatggga cccaatatga tgcagaactg caaatctcac catttgaagt gtaaacgttc    204780
     cataaccagg gcttgtcagc atacacagta tcgaatttaa tacccgactt tgggtttctg    204840
     atttcatatt caatttgtaa tgtaattgga gtgaaaacag attcttgaaa cccaggggta    204900
     gtcttaattg aaggagtaat cggagtgtaa ttacttaatg cattggcgtc ctccaaagat    204960
     attttgatgg aagatggtat ttttatagtt aactgggatt tagagtccgt ttctgggtat    205020
     tcattcaagc tagcaaactt agatctcaaa aaatgtgact gttcaatgga attgtcgctg    205080
     tataatacat tttgtgaagt caatccattc aaatttgttt gaagtgggtc gtcatgaata    205140
     aattgatcac atcgacgatt ttcgaccaga acatctttaa tagtcatttc cttgcaatca    205200
     aaagttacat attctaggtt ttggatcaac ggaatgatta ttatagtagc gctaccggta    205260
     atgcagtgag tagctagatc tatatccaac gagatttttt catgggcaac tctaaaattt    205320
     ctaaacttca tctcatgcaa agtgctagat tcactaacaa tggctctagg agtggcgttt    205380
     ttggaaaagg acatcatgaa gtccacctat ttatcctgtt gtcacctctt cactgtccaa    205440
     aacttcatca aaaaatactt ttacatccgt tccattttac tatagttttc atcttacgca    205500
     atttaccaat tgccccattc ggcaaaagta tttaagtgtt acccggttac ttaaggtaat    205560
     accaaaaata ttcactatat tgaaagttct atgtatttta ttgaattaaa taagactgat    205620
     tttgtagcac gatatccgca agaatgattc acaaccattt tagatgtctg cagctttttt    205680
     ttttttgatt tttttactaa ttttagtgcg attttagaat aactcttgga ttaaataaat    205740
     aaaaaaaata caattatcac tcagattttg aagcaatctg ataaaaattg cagcatatta    205800
     ttataacaat tctagttcac tacaaacagc acattatcaa gaaacttatg tttgatggac    205860
     agtttcttca aataattgaa tgcagtaaaa aataaaaaaa ataaccatgg aatatgtttc    205920
     taagaattcg caatccttgt ttatataact atagcttttt ttatgttata agaaaacatt    205980
     tattccttta accaaaagga aaaaggtaac aaccccactt acccctctgt caatagttaa    206040
     tcattttatt attttcaact ttaaacatcc aaaaaaaata aaataaatta aattaaaatc    206100
     aaatagaaaa tgcattatta ctataataat atctctatgt agacatatac atattatttc    206160
     attgcttttt gtaataaacg aggaaaatgg tgggataaaa aaatgcattg ttattccttc    206220
     gaaaccagca gtaataagtc gtcctgagaa cgatgtagat ttagatcttt acatgttggt    206280
     actctaaatc acctccttcc atcttaaagt cgtccttctt cttgctccaa tcaaacttgc    206340
     ttttcttgct gctgggacac caatttaaac ttattaacca gatagtaaac aaaatcatga    206400
     aacaacagaa ataacaccaa aaatgatcgt aaacgtgacc ccttatgata tcacacactg    206460
     aataatcata cacttcatcg tctataacca gtccataatt gaaataaccg agtccgtatt    206520
     tcaatacagg tttatatcca ccttcatcgg taaacgtact tggactcaaa actgtgctta    206580
     gatcattagt tccttggaat gcatgttctc tcaataagga agcatcaagt ggagctggga    206640
     tcatcctttg ccaaagtacg ttaagagcgc tttcactgcc tactgttgcc ccaaaaattt    206700
     cttggcctta tcttggcaca aatattcttt tgcatttagt tctatacata cagaaagagc    206760
     gaaaaaaaag tgaaaaataa acagaatgtg ataacggtaa aagaaaatca aaaataaaca    206820
     aaaaaaaata catatataac tattattcat gatagtaaac aggtgaatta agatatttag    206880
     tacaattgtc tattacccca ataggcataa tcctcgagga aaaagtcgta caatacccac    206940
     gagggccata ttgtgcacag atgccatagc gcatgggcat caatctgcca ttcgtaacta    207000
     aaaaagtcaa acagttccaa tgacatggcc attgtggtta caatcacaag aagaattgga    207060
     atgacacaca gtttgaagat ttgccgcttg aagctggagt acgcggtttt cttgaattcg    207120
     cccattagct tttgcttttg cagagcatgg tagttttggc atgataacat tatcaataaa    207180
     atatactgta aaacaccgaa aaaaatgttg aatctcatgt tgtatgtgta cgaccagtca    207240
     acatagagtc tcaagatgtg cagggcaaag attgccgcaa ctgacgcagt gaacgcttgt    207300
     gctatcttgg ggtacaggaa catggaagtc attcttgcaa atattgcatg aaaccctgtt    207360
     aggacagtta aacctgcgaa aaagtaatct agcttctccg ttatgatcaa atcacgacag    207420
     tgaaagaccg agcttgctgt ccaagccaac attcccgcca cagtaacgta aaggtagttc    207480
     caaatcagta tacttctgct gttttttctc ctcctatctc cctcttcgcg tatgattcta    207540
     gaaaacttta caaatccctt ataatgtgga ataaagttac ctatactgaa tatcgtcgag    207600
     aagaattcct gagtccccaa tactctcaaa aatggccatt tcccatggaa ttggtatatt    207660
     tcttcctctt cgtcaattct ccagcgcgta atgatgtgct gacattggta atcacaatct    207720
     gagatacaat cccagaacaa taacttagag tacaaaggcg gggtatcgaa aaactcaata    207780
     tcatgaaaca tgttggtttc agggtcaatg tagtttattt gggaattcgg acatcttctg    207840
     ttatactcgc acgcatacgt acagtctata aactcatcta aattatctcc tggagagcat    207900
     gtcactagga aacagtgaac aagtagggtc acaaccacag ctaacctcat atttcttgcc    207960
     acacttctgt ttcttttctc ccgaagggta tggtttcaca ccttaggttg ctcttttatt    208020
     cgctttatga aaaatgaaaa atgaaaagta caagaatacg caagagaaga gcgaaaaaac    208080
     taatgttgac atgacattat gcaataattt atttatgaga gaaagagaaa aacactacaa    208140
     atttttcata aaatcacgcc tcttcaatcg aatctcacca agaggtagtg tgacatcgtt    208200
     attccaaccc cacagttttg aaccagattg aagattctca gacataggag tttgtaaagt    208260
     ggcattgtac tcctccagtt ccttagcaat tgcctctatg ttcaatcgag ggaacgtttc    208320
     gtcgtcatat ggatcgtcca gtttatcgac gccgttgtaa agaatctggt ttggcgtaga    208380
     aggcttgaaa aacaacgttc ttctatggaa aacattacgc gtggacaaat actcaatctc    208440
     ctgtgctatc atttcaggct caattccctt cgagagtagg atcgctgcaa ctccggtgac    208500
     aatgggcgtc gacatagatg tacctgacaa aattaaagtg tcgttgtagt tcagatgaga    208560
     tagcgactca atttccacgc ctggggcaaa gatgtttaca cagggccccc aattgctgaa    208620
     cttggcaatc gtgtcaatgt ggtcatcaaa ggcccctacg gtgataacgt tttctgcaga    208680
     cgcaggtgag gcccagtagg cgtctaaatt gaagttcccc gccgcggcaa caaatacaat    208740
     accttcttca atggccccct ccactgccat gttgattatg gggctcctga aactccctag    208800
     acttagattg gccacgcatt ttttaccctg tgggcgactg acctttgtgc aatgttccac    208860
     gatgaactcc agaccactaa gaacgttact ggcctcgcca gacccgtctt tgcccaagac    208920
     tttgacctcc acaagattga ccctctttgc cgctccatac gttttggaac ctacgagtcc    208980
     cgccacgtgc gttccgtggc cattctggtc gccaaaccct tctttggtca agtcaatccc    209040
     ctggatgact ctgtcttcga attccggatg gtccgcgaag atacccgtat ccatgatata    209100
     ggcgttgacg tcttgacctt gatagtcgtg ttcatagtag taattgaacc agcttttgta    209160
     gcggtccttg tccccaacgt cgaatgggag ttggtagtgg cgggaaatcc gggccaagtg    209220
     acggggtgcg tctggttgat acgttatatt ttgctcttcc tcgacgtctt cgtacgagta    209280
     tttggcggta gcgttaaacg tataactcga ctcggcgcta tttacactgt cgccttcaaa    209340
     agcttcgaac ctgaagttgg gcacaatatc agccaccagt gggcttttct tcagcttgtt    209400
     cactaagttc ttggacaggt tcatggtcac gccgcggaag gatccgatgg agaatttctt    209460
     ctcaattttg ttgtcgatga actgtctcca tgacctgttg gaattcgaag tgaattgttg    209520
     gaatgctgtg ggatttttga acctcaccaa atactcctct gcgtatgcga ggttgaccag    209580
     caaagagatg agtatgcact gtggcttcat gaccagtgtt tttttgctgt ttttcttggc    209640
     ggatgttaga ggatgtctag cacttgagta tacctctata tgctgtgtaa aatagaaaat    209700
     aaaaaagcca atgagaacaa tattttgtgt cgtttttttt attttcgctt caattctcta    209760
     tacacgtacg tcatcactac gggaaaccaa aaaaaaaaaa aagaaaacag tacaaaaagg    209820
     tttactttac ccatagttag tatacgtaga ttttatacac gcactatttt tcttatatac    209880
     aggagatggg tggccacaga acccgcgcct agcctatttc tttcttctta gacctgcctc    209940
     gaggtcgccg acatccaacc ttgtacctct gatgtagtag tgtttgtttc tttgtctgct    210000
     cgagacgtgg ggggttagca agtcgattct ctcgatcagc ggcgaaaaca atggcactct    210060
     aatctcgacg gccgtcttgg ctatctggtt ccgcaacagc aacgaggcgt cttgcaccag    210120
     ttgtttgcgg tctatggaaa ggatgtagcc aacaaaggtg tcgtacgagc acttggacga    210180
     gtcgtacaca atccggacca cgtcgcctgc cttcaagcgg tccttgttct ttttactgat    210240
     gagcttcctc ttaacggccc cgggatccag agactctatt tctgagaggg ccacctgctt    210300
     cataatctgc gacgaagcta tgcgctgcac aggtgggtac acggggatgg tttttctctt    210360
     ggtggcgggg accatgtagg accttgtcca tgatccaagc aatctgacgt tcctgctcca    210420
     catcgctatg gttctctctc cctttcagca gctgctcaga gggaagactc gattcttctt    210480
     cttcttcttt actgggagtt ccaaagcacc aaaattgaaa accaagaaaa aaaggaaaat    210540
     acatcactac ataaaagtgc gcggagccat tgaccactca catacagata taagtgtata    210600
     tatacaagta tacatataca agtatacatg tagaaggaga cagagacaga gggaaatgta    210660
     taagtgtgta tttttatagt atacaaaaga atatgcgtgt gaggatgtgt gtttcttcta    210720
     gaacctgtgt cttcttttcc tcccggtgaa cttggagtcc ttcgcaactt tcctcccacg    210780
     tcttttcatg agctccttct ttcttagaat gaaactcttg gcagactcct tgtctttgcc    210840
     tcccttcaag cgctggcgca gttgtttctt caagttgacg ttctcctcgt ccatggtcac    210900
     accgtccaaa ttcacctgct cctccccctg cggtggggcc ccactgctca acacaaggta    210960
     gtacttctta ttctttttag actctgggtc gtccaccaca agcccgccac tgaaccctgc    211020
     caccttggca gactgcagta tgtcgtccac ctggtcgtcg tttttcgggt agaactgggc    211080
     cacaaatttc cctcccttct tcagtgcagc atacaatgtg ttgaaaaacc tcatcaaccg    211140
     ctgtttagga tcgttgtatg aagtgtccgc attgcacagc cattggatcg cactgatact    211200
     aatagccgcg tcaaacgagc ccgcccggaa cggtatcccg gtgcccatat cctgcaacat    211260
     caagtcgccc tccagctctc tactaagacc ggtcgcaagc atgctgggcg atatatccaa    211320
     accacaccac acatggtctc cctcctgcgt caaaatctcc ccagacagtc cggacccgca    211380
     cccgatatcc agaatgaaac tgcacggctg cagattcaaa agctccaacg ccctcagcgt    211440
     catcttcgcc tggatatgct gcactctggt cgaacccgtg tacttgtgtg cttcgctatc    211500
     attatagaaa atctccggtg gtgccaactc ctcaggacgt gacattattt cttctctgat    211560
     atatttcctg tgtttccgta ccgcaccttt ttagcactac ttttttacta tgctcttctt    211620
     cttctgcttc ttctgctttt ttcctcttta tcacactatg tatgtgctgc tcatctcttc    211680
     tttttatcga taaaattgaa aaatgtgaga tggtgtagag tgaaaaaaaa aaaaaaatct    211740
     ggcttggcca tcaaataccc ggccgtggtt ggactcgttt agcgaacaat agcacccagc    211800
     agaccctggc aacatgcgga tgatataaga aggacgagcg tggtggagga aaggggcgcc    211860
     attggcacac tcacgcaggt ggttgttcag cacggcttgc agcaagagcg ccaaaacaga    211920
     ttgcaagaat gacggagact aaggatttgt tgcaagacga agagtttctt aagatccgca    211980
     gactcaattc cgcagaagcc aacaaacggc attcggtcac gtacgataac gtgatcctgc    212040
     cacaggagtc catggaggtt tcgccacggt cgtctaccac gtcgctggtg gagccagtgg    212100
     agtcgactga aggagtggag tcgactgagg cggaacgtgt ggcagggaag caggagcagg    212160
     aggaggagta ccctgtggac gcccacatgc aaaagtacct ttcacacctg aagagcaagt    212220
     ctcggtcgag gttccaccga aaggatgcta gcaagtatgt gtcgtttttt ggggacgtga    212280
     gttttgatcc tcgccccacg ctcctggaca gcgccatcaa cgtgcccttc cagacgactt    212340
     tcaaaggtcc ggtgctggag aaacagctca aaaatttaca gttgacaaag accaagacca    212400
     aggccacggt gaagactacg gtgaagacta cggagaaaac ggacaaggca gatgcccccc    212460
     caggagaaaa actggagtcg aacttttcag ggatctacgt gttcgcatgg atgttcttgg    212520
     gctggatagc catcaggtgc tgcacagatt actatgcgtc gtacggcagt gcatggaata    212580
     agctggaaat cgtgcagtac atgacaacgg acttgttcac gatcgcaatg ttggacttgg    212640
     caatgttcct gtgcactttc ttcgtggttt tcgtgcactg gctggtgaaa aagcggatca    212700
     tcaactggaa gtggactggg ttcgttgcag tgagcatctt cgagttggct ttcatccccg    212760
     tgacgttccc catttacgtc tactactttg atttcaactg ggtcacgaga atcttcctgt    212820
     tcctgcactc cgtggtgttt gttatgaaga gccactcgtt tgccttttac aacgggtatc    212880
     tttgggacat aaagcaggaa ctcgagtact cttccaaaca gttgcaaaaa tacaaggaat    212940
     ctttgtcccc agagacccgc gagattctgc aaaaaagttg cgacttttgc cttttcgaat    213000
     tgaactacca gaccaaggat aacgacttcc ccaacaacat cagttgcagc aatttcttca    213060
     tgttctgttt gttccccgtc ctcgtgtacc agatcaacta cccaagaacg tcgcgcatca    213120
     gatggaggta tgtgttggag aaggtgtgcg ccatcattgg caccatcttc ctcatgatgg    213180
     tcacggcaca gttcttcatg cacccggtgg ccatgcgctg tatccagttc cacaacacgc    213240
     ccaccttcgg cggctggatc cccgccacgc aagagtggtt ccacctgctc ttcgacatga    213300
     ttccgggctt cactgttctg tacatgctca cgttttacat gatatgggac gctttattga    213360
     attgcgtggc ggagttgacc aggtttgcgg acagatattt ctacggcgac tggtggaatt    213420
     gcgtttcgtt tgaagagttt agcagaatct ggaacgtccc cgttcacaaa tttttactaa    213480
     gacacgtgta ccacagctcc atgggcgcat tgcatttgag caagagccaa gctacattat    213540
     ttactttttt cttgagtgcc gtgttccacg aaatggccat gttcgccatt ttcagaaggg    213600
     ttagaggata tctgttcatg ttccaactgt cgcagtttgt gtggactgct ttgagcaaca    213660
     ccaagtttct acgggcaaga ccgcagttgt ccaacgttgt cttttcgttt ggtgtctgtt    213720
     cagggcccag tatcattatg acgttgtacc tgaccttatg aactgccacc ataccacgtg    213780
     tgtccctcgc aagcccttga tagatataca atagggaatg ggcgtccgct ccaccgtggt    213840
     caaagacagg ggcaaagagc tcctaggtct atatatatat ctatatacat atttatatat    213900
     attattagaa ctttacaata tagtatatac cattcattgt ttaagtttcg ggtaatactt    213960
     tttttttcct tgtcataacc ccaaaaattt tcgatgcctt tgatataatt gagaacaaga    214020
     agagtttgca ggtgacaaaa atcgatgatt ataggtgttg tgacgacaaa atgaacgcta    214080
     atatatgggt ggctgcttca gatggtaatt tggaccgagt ggaacatatc ctccgcgaga    214140
     gtaaaggcgc catgaccccg caatccaagg acattaacgg ctacactcca atgcatgctg    214200
     ccgccgcata cggccacctg gatttgctga agaaaatgtg caatgagtac aatggagaca    214260
     ttaatgtgtt ggacaacgac ggcgataccc cgttgcacca tgtggaggat gtggccactg    214320
     ccaggttgat cgtggaagag ctgggtggag acttcactat caggaatgtg gagggccaaa    214380
     cgccatacga ctcgttcgtc gagaacggtg aagatggtga gctaatcgag tacatgagga    214440
     ttaagtccgg cgtggccgat gttcacggag tggacggcgt gcagggtgag ggtgtcatcg    214500
     acagcaaatt gctggaagag ttcaaggaca acgtgagata caccttggaa aatgaccctg    214560
     aggaaggagc cgatgaggcc actctgcaac gcaggaggca gttggaacag atcattacgg    214620
     gagacaacgc tgaggaggag ttggaaaggt acatccgtgc tatggtcaga gagcagatgc    214680
     tgggccaggg ctccatggcg ggttccgggg acgaaccaga ttccaagaga agaaaataac    214740
     gacccagcac aaaggctctt acagcttgct aaaagaaatt gaacgcgacg ctacatgaac    214800
     tacttctttc tcttacatag tcttttccct tatgtatctt ttctgtacat taatagacgt    214860
     tcttacaagg taaaatttca ccgcgttttt aaatagaatg aaaaaaacgt tgtagagtga    214920
     aagaaaagca acaaatatac agttcacaag gcagcttcgt atagtaatac agcacgaaaa    214980
     acagctcata gaaatggtaa cacagaccaa tccggtccct gttacatatc caacggatgc    215040
     ttatatcccc acgtatctgc ccgatgataa ggtctccaat ctggcagatt tgaaaaaatt    215100
     gatagaaatg gattccagac tagatttgta tctgacaaga aggaggctgg atacgtccat    215160
     caatttacct acaaacacca agaccaagga ccatcccccc aataaagaga tgctgaggat    215220
     ttacgtctac aacactacgg aaagcagccc tcgcagcgat tctggcaccc cagcggactc    215280
     aggcaagact acatggacac tgagaataga aggtaagctt ctgcacgagt ccgcaaacgg    215340
     aaagcaccca tttagtgagt ttttggaagg tgtcgcggtc gactttaaaa gactgaaacc    215400
     gctgggcatg ggcaagaaga ggaaacgcga ttcgtcattg agccttcctt tgaatctgca    215460
     acaacccgaa tacaatgatc aagatagcac catgggcgat aacgacaacg gcgaggatga    215520
     ggacagtgca gaggcagaat ccagggagga aattgtagac gcactggaat ggaactacga    215580
     tgaaaacaac gttgtggagt ttgatggtat cgacatcaag aggcaaggca aggataattt    215640
     gcgatgcagt ataaccatcc agttgagggg tgtcgacggt ggaaaagtac agtactcgcc    215700
     caacttagct accttgatag gtatgcaaac gggctccgtt aatgacgcgg tttattcgat    215760
     ctacaagtac attttgatca acaatctgtt tgttacggaa caaacagagg ctcaagatgg    215820
     ttccaacgat gccgaagaca gcagtaacga gaataacaat aaaaacggtg ctggtgacga    215880
     tgatggcgtc gagggaagta ctccaaagga taagcccgaa ttgggtgaag tgaagctaga    215940
     ttcactctta caaaaggtat tggatacaaa cgccgcgcac ctccccttga tgaatgttgt    216000
     gcaaaccgtg aacaaactgg tatcacccct accgcccatc atcctagatt atacaattga    216060
     tctttccaaa gataccacct atggtgctac caccttggat gtagatgtgt cgcacattct    216120
     ccaccagcct caaccccagc caaatttaca aaaagaggaa gaaacagatg ctgaagacac    216180
     agcaaaacta cgtgaaatca caaagcttgc cttgcagttg aactctagtg ctcaaaaata    216240
     ccagtttttc cacgaactgt ctttgcatcc aagagaaacg ctgactcact acttatggtc    216300
     ttccaagcaa aacgagcttg tgctgcaggg cgaccaatac ttcaatgaag atgctgcaag    216360
     aacgagtgac atatacagta acaacaacaa tgacaggtca ctaatgggca atatctcact    216420
     actgtactcc caaggaagac tataacatca ctgtatgatc tcattctttc tgcaattatt    216480
     gcacgcctcc tcgtgagtag tgaccgtgcg aacaaaagag tcattacaac gaggaaatag    216540
     aagaaaatga aaaattttcg acaaaatgta tagtcatttc tatcaataac gtatacacgt    216600
     ttttttaata ctatctatat tgtgtatctt atatttttcc atttggtagt atagcagcaa    216660
     atatttgttc ttagacggcc accatccctc acaccaatgc ctaacgcttc ccaagtttac    216720
     agatctacca gatccagctc tccaaagaca atctcttttg aagaggctat cattcaaggt    216780
     ctggccactg acggtggtct tttcattcca ccaactattc cacaagtgga ccaagccact    216840
     cttttcaatg attggtcaaa gctctccttc caagacttag cctttgctat catgagacta    216900
     tacattgccc aagaagagat tccagatgct gatctaaagg acttgatcaa gagatcttat    216960
     tctactttcc gttctgatga agtcaccccc ttggtgcaaa acgtcactgg tgacaaggag    217020
     aatttgcaca ttttagaatt attccacggt cctacctacg ctttcaaaga cgttgcttta    217080
     caatttgtcg gtaatctttt tgaatacttc ttacaaagaa ccaacgccaa tttacctgaa    217140
     ggcgagaaaa agcaaatcac tgtggtcggt gctacttccg gtgacactgg ttctgcagcc    217200
     atctacggtt taagaggcaa aaaggacgtt tccgttttca tcttatatcc aaccggtaga    217260
     atttccccaa ttcaagaaga acaaatgacc accgttccag atgaaaacgt ccagactttg    217320
     tctgttaccg gtactttcga caactgtcaa gatatcgtca aagctatttt cggtgacaaa    217380
     gaattcaact ctaaacacaa cgtcggtgct gttaactcca tcaactgggc aagaatcttg    217440
     gcccaaatga cctattactt ttattcattc ttccaagcca ccaacggtaa ggactccaag    217500
     aaggtcaagt tcgttgtgcc aagtgggaac ttcggtgata tattggccgg ttattttgcc    217560
     aagaaaatgg gtttgcctat tgaaaaactg gccatcgcta ccaatgaaaa cgacattttg    217620
     gacagatttt tgaaatctgg tctatacgaa agatcagaca aggttgctgc tactttatcc    217680
     ccagcaatgg atatcttaat ctcttctaac tttgaaagac tactatggta cctagctcgt    217740
     gaatacctag ctaatggtga tgatttgaaa gccggtgaaa tcgtcaacaa ttggttccag    217800
     gaattgaaga ccaacggtaa gttccaagtt gacaaatcca tcattgaagg cgcatcaaag    217860
     gactttacat cagaaagagt ttccaatgaa gaaacatctg aaacaatcaa gaagatctac    217920
     gaatcatctg taaatccaaa acattacatc ttagatcctc acacagctgt cggtgtttgc    217980
     gccacagaaa gattgattgc aaaagataat gacaagtcca tccaatacat ttctctatct    218040
     accgctcacc cagctaaatt tgccgatgct gtaaacaatg cattgtctgg attttccaat    218100
     tattcatttg aaaaggatgt tttgcctgag gaattgaaga aactatccac attaaagaag    218160
     aaattaaaat tcatcgaaag agctgacgtt gaattggtca aaaacgctat tgaagaagaa    218220
     cttgctaaaa tgaaattata agatcttcct ttttaatgaa tatattttat cttatataac    218280
     atatagaatt ctataattaa tagagagtat gaagtacgat tatccttaat gttaatcaaa    218340
     gtgaatcatg attgcgagag taaggaacca taaaattaat cttcatctat gctaataatc    218400
     tcagaattct cgttcccagg gtcttcttct ttagatacta atctaacttt cccgcccttt    218460
     tcaactgata tttcaaaccc agctttgctc aatgcatcgt cttgaacaac gtcttgagct    218520
     tccatttttt tgacatattc ctgattcttg gcattattct ttaacaaaaa cttcaagcaa    218580
     acaatagatc tttccttgat aaacggatca ttatcatcga tgacacaatt ggaaagaatt    218640
     aatgcaagac cacctaattc tcttatttga tcttggattt caggatgtgc atacactaac    218700
     gatgccaata tttcgattat tactaattta caatggggaa aattatcagc cctaataaag    218760
     gattcgttgg tattaacacg gttgaaaatt aataaccggt cctcgatttt gttaccttca    218820
     tgatctgtga ttttaatttc attcaccgta tcaccgtttc ctttcaaaaa attaatcctc    218880
     aacaaattct tttggaaagt atccaagaga gataccaata ttttcacaga gtcatacgaa    218940
     attaagaatt ttctaacatg attgaatttg cacaagtcag aaattatgtc caggcaagaa    219000
     agtaaagtgg agtgtaattg gatggcaact gaaggagcat aatcgttaca acttttattg    219060
     aaaaaggcag gaatatcctt gcatgcaaga cgttgcagaa tggggtagca ccatgacata    219120
     attgcagtca actcataggt attccaatct tctttactcg ttacaaccaa ttgcaatatc    219180
     tgcaacaaag tggtgaattt tcctggctgt ctttcttcta acccattgag gtatttacca    219240
     aaagaagcag ttgtaagact tttgctaata cattctaaga cagataggtc aatagaagtt    219300
     atttccaatt ttgaatcatc cagatagttt ctgcccttct caattaaaaa ggaattctct    219360
     tgatcctgga tgaatttggc tgtcactata tcgaaaaata ttctatccct aacacaataa    219420
     tagtctttct ggggtgtatc attatccctg aaaaattcgt tggaaaattc atcattgttg    219480
     agatacgtct tgaaaagaaa taaatatggt agccagaaat gctcttcttc ttcaccgtct    219540
     tccaatttga tcccataagg gtattgaaga aattgtaaaa gagctggaaa agtagtcata    219600
     tccactgtag agtagttctg ctgtatattg aaaaggcacg ttaaacatgc gatgtataga    219660
     tgtttgatta gcggagtgtc aacgacatac tcactagttg catgcagaaa accacgaatt    219720
     acgaggtttt gtagtaaaag cttttggggt atttcctggt tttcagcggc aaggtttctc    219780
     atcattaaga taaggcccct cactgttctt gtatacggta ttgagctatt ctcatttaac    219840
     gacgctggca acagcattgc ttccaaggtg tctcttaatc gttcccaaaa aagctgggag    219900
     ttagccattg atttcctatg ttcttcatca ttaaacgtcc tttgaaatat acggttcagg    219960
     ttttcgacga ttggctcata atcctcgacg caacatgggt cgttcttcat catggtaatg    220020
     attgaatcaa ataaattgaa ttcatctaga aaattgttca taggcattgt tatttagtta    220080
     tcttcttttt tgatgaatca ataattttat aaggcttagt gtaattgttc tcccgatgat    220140
     agtatgaaac ggtagtcgat aaatttgtgt caaatttttt cctcatccca tcaattcttc    220200
     attttttccc ttcctatttt tttttttact gaagcgatga tgccttatat ataaggaaaa    220260
     tagcctcgtc agtcaaagga cgactcccgt aatggtagcc tcagtttata ttaggcgctc    220320
     tcatcatgat gtatatcgat attggcgatg atattttttt ttgttgatat taaatacaaa    220380
     tgtaatgctt tatatagttc tatacttggg gaatacatga tgtgaatgtg cataaataga    220440
     ggacagtgaa tatttttcaa ggaagctctt tctcattttc ttcttcatca ctggaatcat    220500
     tttcattaga caagggtaat ttgttatcct tcccattgaa accaatccat ccttcctcgt    220560
     cgtcagattc catgactaca tcgttctctt cgttctcttc gttatcttca tctgcgtcat    220620
     cttttaatag aacctcgtca tcatcagccg cgccatcttc catggaccca tcagttgata    220680
     ccaaaaatct ataggtgtat ttgttatcag tagtggtatt gactacttcc ttagccactc    220740
     taacaataaa tctttgtatc gacctcatag ccgtcgagaa gagatatttg tgttcattta    220800
     tgtaaccacc gctcgcagat aatagagctt tgatccaaat taggttaaac tcaatgtgtt    220860
     gggattcaat ggcaaaatca ccgatgaact tcagaatcct cggtaaatat attgcaggaa    220920
     tattacttgc aaccaagggg atttccttaa taggtatggc ttcatagact ttattgatca    220980
     aatattcttc atttaacctg aacgccatta ctaatgcatt taaaaactgc ttttctcgta    221040
     gcgcctctac agtagaatgg ggggtgacgt ccacatccag atcaaaggga tcaaataata    221100
     tcgtgtcatt ggtggaatat atcaataaac cttccgttga agcagcggca aatgcattcg    221160
     ccgttgggga gaattgcacc gaagtaactc taacctctgg tctcattttt cttgtggaca    221220
     ggtcgccacc tctttgagac cctggtaaag aattatcaat acgatcctcc aaatctgaat    221280
     tttcgcctgc atcgtcaatc aaatctaatg aacctgcttc agtcattttc ttactgttta    221340
     aaaattcgag agtaccattc aaagccatgt ttctggacac aatgaatctt tttaacaaga    221400
     cttcatttgg aacatcatat agacaaatgg agttattatt accaccagcc acaatagcca    221460
     taccatcaaa actgtaatgt attgtagtaa aaaatttgga tcgttcagaa tttttggcag    221520
     tgaacctatc ttgattaaac ctaccagata ttatatcctt tctacagtca atgttgccca    221580
     cctgcttggc atcttctatg ttgaaaatgg atatttgacc ctttaaggta gatactgcaa    221640
     cttctttacc atctggtctc attgataagg ctaaaacatc ggaataaact tctataggtt    221700
     ctacttgttg gcttctacca aatatggacc agattctaat tgttttatcc catgatgcag    221760
     aagctaagac actgttctct tgactaaatg aaagacacga aacagggcct tcatgtccgg    221820
     acaaagcatc taataattga ccagtttgca cggaccaaac atgaatgtca aaattgtcca    221880
     gggacccggc acaaaccact tcacctgatg gatccaccgc taaacaattg aattggattc    221940
     tttcagtacc agtgaatgtt ctaaaattac gatacctgat taagtcccac gctctcaccg    222000
     taccatctaa cgatgatgag aacatgacct gacccctttt cgcaaactgt acagcagtaa    222060
     ctgaagaggt gtgttcttca aaagtggcca aacaaaaccc tgatgtaatg tcccaaactt    222120
     tgattttccc atcttcggat gctgtcacta cacgtgaacc atccggagag tatgcaagac    222180
     tatttgtgga atcgaaatgg ccctgctgct tcaagatata cgattccgat tgccattcgt    222240
     aaactagtaa ttggcccagt ttgctggaac caaacgccag ccattcgccg gtttggttga    222300
     cgctaacggt gttgactggg ttttgcccca tagaaagctg ttgaatcaaa gtgaaatcag    222360
     gcaaatcgta aagacggaat tccccactag taaatccgac agctaaaagc cttgttgctg    222420
     gatggaaggt gacacacttt actttggctt ggtttgcgta aaaaaaatgt ttctttgtga    222480
     ttctccagct gtatttcgaa atatctactt cttcttgctt gtcgtcgtct tcactttcat    222540
     tgtcgtcgtc atcggatggc ctcttggtaa attcccagac aaagacagca ccgtctttgc    222600
     ttacagtgta gattttttcc tgatcatgac tgaagaacgc acccataacg tagtctctgt    222660
     gcccattaaa tgttgtcgcc gcaaggttct tttcctctga atctacggac catatttttg    222720
     cgcttaagtc tttggaagtc gtaaggataa atctggaatc ttgtgaccac gtcaaagacg    222780
     ttatgtcttg aaagtgtccc gcatgcaccc tatggcggac gaagggagca aactgtctgt    222840
     ctttattaac atctggagtc ttccaaatct gtaaaaacct gcctgaggct aatgcaaaga    222900
     gtctcccatc agggctgaac ttcacagcgg agcatttttc tttgaagttg aaatggtgaa    222960
     gcacgttacg ggctttgaaa ttgacaagga tggcgcgacc gtcctcgtca atagaaatca    223020
     gcaatgtgcc ttgtttgttc agatcaatgg cagcaatatt tttgcgatgc tcgtattcaa    223080
     acgtgaacga tttgttgttg attaagtcaa acacgctgac cctattcccc accggtgaga    223140
     gtagttgctt gccatcatcg gaaaaggtga tgttaccttg cctgtagacc gtacctaaaa    223200
     ggttagagaa cttgaaatcg gatttcattg ggatgcggtt caatctgcgg tctgctctcc    223260
     tgtctacctg ttgaaaacga tactattatt actattattg atattatact agttattgta    223320
     catacctaga actatactcg aaactttttt ttttttcatc tttcagctca tcgcaaaatt    223380
     tttccaaaaa atttcaaaaa gaactcccgt cgcatgtgat caaggttaca ggtgcttgac    223440
     ataatcataa tgattacgag tcgaagccgg ccctgacaac agcttctctt gccgtagaat    223500
     tgatgtgttt aaaccggtcg ggacctatgt gggcaccgcc gaaccaacgg gccaccacaa    223560
     cgatgacgtt ccacacatcc atgatggtga tgaggtgcag cattctggag ccggcggccg    223620
     tttcaccgtc atcatcggaa tcttgatatg ttgccgcaga gccatcctgc ttgattcgcc    223680
     atgcactcat gacatggttt gccttacgca tcttggagtc ggtcttcagt aggtctagca    223740
     tggcaaacgc ttgttcctcg gaggtaacat gtgctgcaaa ggccatgaaa gtcgagcctc    223800
     tatcagtaat ggggtccgac gcggtccagc cctcgaaggg gtctgtggga atgtcactct    223860
     gctggaccgg ttctgtctcc tcctctggtt caacgtacaa gacaccgtcg agttctgtga    223920
     ggaagtcaaa tagacagaca gatccgcggt ggaaaacaga gtccatcact tcctggaaca    223980
     aatgctgaag gtacttggta tcgtagagat cgcgcttagc caaagaagtg cagacaccaa    224040
     cttcgatgac attaggagcc tcctcggagg ggtagtgtgt cgggaaggag atctgcagtg    224100
     tcatgtattc atgctgcggc actttcacaa cgatgatgct tccgtcttcc tgcttcttgg    224160
     agagaagatc cggatagatg gcctcgacgg cctccagttc ttcgaccaac tgttcgtgat    224220
     cgtcatccat tgagcttttc tttcctctct cttttttttt tcttgttaca tattcctata    224280
     tatatgtata tatatctata tatatatata tcccagcgta tatgactgca caagacgcaa    224340
     ttttcttgaa cggttttttc ttttcagcac tgcgaaagag agagcaacgg taaagagcat    224400
     gagccaattt gaaaagcaga aggaacaggg caattctttg ttcaaacagg gcctgtatcg    224460
     cgaggctgtg cactgttatg accaactaat tactgctcaa ccgcagaacc cggtcgggta    224520
     cagcaacaaa gccatggcgc tgatcaaact gggtgaatat acacaggcta ttcaaatgtg    224580
     ccagcaagga ctgcggtaca cctcaacggc agagcatgta gctatcagat ccaaattgca    224640
     atatcgtcta gagctggcac agggagcggt aggttcagta cagatccctg ttgtagaggt    224700
     tgatgaacta ccggagggat acgaccggtc ctgagaaaag agaaagggaa cacttctaat    224760
     ttatctttaa aattatatat atatatatat atatatgtgt gtttgtatac tctgtgggta    224820
     tttccgtgta tatggttaat aatagtagta tcttgtcagt tttttttatg tttttcttcg    224880
     cgcgtcaact ttctaccaag agaaaaacaa tataaggtct ccttactcta taggagaata    224940
     aaacaaacaa aaataaaaag cacatcgtag cgccaagaaa atactgcaaa taccaaatac    225000
     cacaataata ctacaattat ctatacacaa gtgttttgcc gcttaaaact tcgattttca    225060
     tagtacgaaa ctatacaccc ttggtttttc tcttttctaa atacatatct accttgtaaa    225120
     gaatttcccg cacatctttg cgggcataca gttcatgtat tggcaactaa cggaactaag    225180
     gcaacatatc ttgcatattg caatgttcac tatatagatg aaaacttata tctaggtttc    225240
     acgacacgag aataactaag aagcacgatc catgatatag aaaaatcagt tacgacgaag    225300
     cacggcaaat tagccgccga agaccgatat ttttgccacc ggtcacagtt ttcttttcca    225360
     cggagctctt cgcggttttt ttgttccgga ttttttttac cggctcttag cggaccgttt    225420
     tggttataag gggagtggca gcggcggtag acactgcgct ctataagaat acttgcaagg    225480
     gtcttgtcta ttgtataatt cgctagtatt tgttttgcat tgtactctta ataccccaac    225540
     caaaaacaaa atagtgagag taatggtgcg ttttgtttca attttaagtt tattcggctg    225600
     cgcggcgacg cttgtcacgg cccatgatga catggacatg gacatggata tggacatgga    225660
     tatggacatg aatatcgata cgacaacgtc tcaatccata gatgtctcat ccacggcttc    225720
     aatcgtcccc gtgccacatg aaccaaaaca tttgcatggc cttcctatac tgcaatcgcc    225780
     ctcgcttacc cctgcggaga gattgtactg ggaaaactac aacaccacaa cctactttac    225840
     tacacaggct gggaataggt ctgcccttcg ctaccacatt attacgctgc tcttggttgc    225900
     atttgtgctc taccctgtgt ccctggcgct aagcgccgcc cgttctaggt ggtacttacc    225960
     cctgctgttt gttaatctat gcatttgtat ttcgtccgta atggcattgt ccgtgttcaa    226020
     aaatactttc ccggaagaag actggtatgc gcataatatc tatggcacca cttctgtgct    226080
     acttctcgtt tttatgcttg ttcacttctt cgctgcggtg ctttctgtcc ccgtctcatt    226140
     agcatcgaaa aaggagtacc gtccggttga caccatccct ctgaatgatc ttgaatctac    226200
     gcccgtcatg gtgaatagtg cacgtggctc tccaagtcct tcttccaaca gagacacgtt    226260
     gttctcgctc tcttcagaca ccacgaccgc cacggccacc aataataata aacggagacg    226320
     cgctgaaggc gaagacgagg gtgataacac ctccaaccac gacactttgc gcgacgaaga    226380
     ctacgataat gatgacgacg aaattgcttc cattgaagcg ccacctctgc ttcctcaaga    226440
     catacccgtt ttccgaatct tgtttaccaa cacgaagtac cagatgcttg ccgcgcacct    226500
     ctcgtgcgtc gccaacgtgg tctttcacat gcttacctac ccgctattca tgtacatctt    226560
     tgtagaccta atcatcggct tcgctgtagg taacttgctc ggcaagggca tccgcatctt    226620
     taatctcttg gcccactgga ttaagggcgg cgtatttttt actctgggcg ttgtctcttt    226680
     agcaagatac tgcggtttcg cagctaagta cggctgggca tggaacaaca tcagcttcac    226740
     ctctcaactc acacaaacgc gttcctccaa tcttcttttc cggtttgctc ctgcggggac    226800
     tttcaccatg gaattcgttg aatccttcct cattttcttt tacgggtcca ccaacatctt    226860
     cttggagcac ctggcaggaa acggcggcgc atggactgcc aaggatttac agcatgtgtc    226920
     gatcgcgttt atgttcatag gaaccggatt gtgtgggcta ctcacggagt acaagctcaa    226980
     ccattggcga ttcgagcatg cccgcaaacg gccacagacc gatgtagttg ctgccacacc    227040
     ggggtactct ccaaacccgt tccccgcttt caccatattt tggactggga ttctgatgtc    227100
     ccagcacgca cagtcctcgc aattttctac taccattcac acgcaatggg gatacttgtt    227160
     gtcctatggg tccttcttcc gtctgctaac atttttgatt ctgtttttgg tgcccaacac    227220
     caacagtgcc gcatccaagc ctttcacgga gttgatcacc tcgttctgtc tcctctgtgg    227280
     tggtctggta tttatggagt ccacggatca gtccattgaa gccatggaat atagggggtt    227340
     tacccccatg ttcactttca acctcagtgt tggattcgtt tctttgttga tggcttggga    227400
     aatgatttta tttatttgga aagactggct catcaaaacc aggaaaacca gtctttaacc    227460
     gccataatgg cttttctttt ttcttttttt tttcaccccc ccctcatctt tgagtgagaa    227520
     gcttatatgc tttacttttc ctcacctact ttttaattct taattattag tttatccagc    227580
     attcagtcaa ttctgaatgc gttatcgctt cctcaaaatt tataaaaatg aataagcaag    227640
     atctcattgg aattgagttc aatgacgatt attgagggcc catacctgat aaaagtgaat    227700
     atattatgta taatgactct actggaggtt ctctctgaga atgtaaaata atccacaaaa    227760
     gacatgaaaa ttagttactc tacataatgt ataataagtt cttccttcct tttttctttt    227820
     tttagttttt ctactcacca tcctacctac gccaagctgc tctactgtct tggatctgtg    227880
     aaaaaacgcc tagaaacatg tataaaacct accgctttaa accataattt caaatcgaaa    227940
     tggcactatg gccgagtggt taaggcgaga gactcgaatg gaataaaaag ttcggctatc    228000
     tcttgggctc tgcccgcgct ggttcaaatc ctgctggtgt cgtttaattt tttttaaata    228060
     acatcgttga ttaaaacaat cctattcact gcagtcacag acttagcaca tttacaacca    228120
     gtacaagatc aatcacacgc gttgtggtag gaactttgac gatgatactg cgttggctct    228180
     tgaacgcata gtacatttgt cgttcacaac ggaaagtgaa atactgaaaa aaaaagaaaa    228240
     attttcttag ggactcatca tcaatgtaaa cacctctaca gccgtcaaga ctagcaaagc    228300
     tcacctcaca aaacgacatg ccgcgcataa agaccagaag atccaagcct gcacctgacg    228360
     ggttcgaaaa aatcaagcca accctcacag atttcgaaat ccaactcaga gatgcccaaa    228420
     aggacaagtc gtctaagctc gcagcaaagt ccaatgagca gctctgggag ataatgcaac    228480
     tccaccacca gcgctctaga tacatatata ctctgtacta caagagaaag gccatctcca    228540
     aagaccttta cgattggttg ataaaggaaa agtatgctga taaattgcta attgccaaat    228600
     ggcgcaaaac cgggtatgaa aaactgtgct gtctgcgctg cattcaaaag aacgaaacta    228660
     acaacggtag cacttgcatc tgcagggtgc ctcgtgcaca gttagaggaa gaagcacgca    228720
     aaaagggcac acaggtgtcc ttccatcagt gcgtccactg cggctgccgt ggatgtgcaa    228780
     gcacagacta acgactatat gcacgttgca gtattgttct ggccatgtaa ttatctctct    228840
     cccaacgttt tagaagaggt tttcgtctcc ttcgtcaaag acgaccactt tcccattttg    228900
     gtcattggaa cgcgaaaaaa caaaacagac gcgagaacgc gacgcgaaaa aatatatttt    228960
     tccgtttttt ttttttttcg gaacaaagat aacgcgttaa aacctgtgga tgtaataagg    229020
     atctgaaaca ctgactaaaa cgcgtcctca tttaaaatca aaaaattact tcttctcctc    229080
     ccttacggtg ccctttgatc cttctcaaac tttaaatata tgttgcatga ttaattgaaa    229140
     atcatataga gtatatctta acagaggttc caacgcttta aatcgtattc tattcttttc    229200
     ccccctttta ttatagttac atctactatt tgagcttctt ttattgaccg aaactacctc    229260
     ttatttcgaa gcaaaaaaaa aaaaaatcaa caaaaattcc aacttttcaa tgatgaatga    229320
     agacatatcc atcattgatg gccataatag ttttttaacg gaaaaaagca ccgtgctatt    229380
     aacccaagcc aagagaacac tagaagacga aaaggaaatg attactcccc cgagctcaac    229440
     tgtgagaaaa acaatgaagg aagtaaataa gaggccgtcg catcccctct caccggatca    229500
     ctcgtcccca attgctccat ctaaggccaa gcgccaaaga tcggacacat gcgctcggtc    229560
     caatggtaac ctaaccttgg aagaaattct tcaatctttg gaaagaagaa gaataaatgg    229620
     tgaactcgcc aagaaacctc catattcgta tgcaactttg atttgcttgg ccattttgca    229680
     atctcaggag ggaaagctaa cgctatccca gatatatcat tggatccacg ttcacttccc    229740
     ttattacaag cagaaagatg ctagttggca aaattcaata agacataact tgtctttaaa    229800
     tgatgcgttc atcaagactg aaaagtcctg cgatggtaag ggtcatttct gggaggtcag    229860
     accgggtgcc gaaacaaaat ttttcaaagg tgaaaatcgt ggttatgaat ttgtaaagga    229920
     ctccttacaa gacattggga agtattttga aatagattct acacttgatg aattagaaca    229980
     agttgagagt ggagaaggca atgatgatct tcctgacgag gaagaaagag aggaagcagg    230040
     gaaattccct tccattgaaa ttcaattgaa ctcctcccct atactgagag tttcccagtt    230100
     acatcacata ccgcaattga aaacagacaa cagtgtactg aaccctcacg aaaacctaga    230160
     atcgatgcgg aacatgatag aaaacgatgt caacaatata gattccttgg aacctcctta    230220
     tgtcatgaag aaatatcata cttctttagg cttaccgtcg ctggtgaatg ccaaagatca    230280
     tttccaggcg ggtgtgaaaa acaataatat cacccaggca aatagattta atacactccc    230340
     tataactagc gcaaagtctc ctcagaattt cagaaaatat ttcacctcat tcaattcaaa    230400
     ttttgaagat ttatctccac ttcgaagtaa tgtaggggct ggttctctac tcgacccact    230460
     tccgtattcc ccattgaagc tgtacgatca gaaaaatctt gcgctcatgt cgaaaccaca    230520
     atctcagcaa tcatattcca attctcaact tccacctcca ccttcctctc atggttcgga    230580
     cttacttaaa acacccaaga tgaggcattc cgatggctta gagaaaaccc catcgcggtt    230640
     gataagcaca cctaaggacg gtaactcgat tttgaggaaa tggcagactc cttcacacct    230700
     ttttgaagat ttgtactgtt ctccgctatt tagagctata gagactccaa tcaggtatat    230760
     cacgacgccg gggggcactt tggaaaccca aatttcacca agaaagtcct ctgcacccga    230820
     tgtcctcaca agcgcaacga attccaaatt tgcttcaagc gggctgtttg gcgtggatgt    230880
     ttattctgtt tggaagcgcg caactgaaaa gatttctgat ggtaacaata ctacggatag    230940
     caatcaaaaa catcatcctt atcataatca cccttccaac gatagcggta atgaaaagaa    231000
     ttgacttttt tttttttttt ttttcatttt cttttcctca ccgaaaacta attattctta    231060
     atctgatgga ttcatcgcaa acggttggat gagtcctaaa ctgggctgga gttatcatat    231120
     cacatagcat tttcttttta atcttattgt attgtcgggt caactaactt cttttcccgc    231180
     tcttctatgg tataatcaat tgcagaagag gcaggaaaaa attgtaatca taacaaaaat    231240
     gatacaaatt ttttttctaa gttttatatt ttacatatct ttatttttga tccttacgga    231300
     tttttaatac agtatttagc tgaagtttcc attcacttca cttacctttt tgatctcttt    231360
     tatttttact tgccccgttg ccttgcattt ttcaatagaa agtgaaaaac taagtaccac    231420
     ttgagcaatg ccacattaga agaaaaacca tccgcaagtg agcatcacag ctactaagaa    231480
     aaggccattt ttactactca tggaccacca aataaccact gcaagcgact tcacgactac    231540
     ttcaataccg agcctgtacc aattggatac acttttgaga tgtcacattt gtaaagattt    231600
     tctaaaagtc cccgtcttaa caccttgtgg ccatacattt tgttcccttt gtattagaac    231660
     acatttgaat aaccaaccaa attgtcctct ctgccttttc gagttcagag agtccttgct    231720
     gagaagtgag ttcctggtca gtgaaataat tcaaagttat acatccctac gatcttcctt    231780
     actagatgca ctaaggatac cgaagcctac ccctgtccct gagaatgagg aagtaccagg    231840
     tcctgaaaat tcttcatgga tagaactcat atcagagtct gaaagtgaca gtgtaaatgc    231900
     cgctgatgat gacttgcaaa ttgttgcaac aagtgaaaga aaacttgcca aaagatccat    231960
     gactgatata ttaccactga gttccaaacc atccaaaagg aattttgcaa tgttcagaag    232020
     tgaacgtatc aagaaaaaat caaagccaaa tgaacaaatg gcccagtgcc ccatatgtca    232080
     acaattttat cctcttaaag cccttgaaaa aacacatttg gatgaatgcc taactttaca    232140
     atcactaggc aaaaaaccaa aaatttctac cactttccct acagagtcaa atccacataa    232200
     caaaagttca tccagattca aggtacgaac tccagaagtc gacaaaagct catgtggtga    232260
     gacctcacat gtggataagt atttaaactc aatgatgagt gcagaacacc aaagattgcc    232320
     gaagatcaat tttacgtcta tgactcaatc ccaaataaaa caaaaactgt catcgttggg    232380
     actgtcaact aatggtacta ggcaaaacat gattaaaaga tacaatcact acgaaatgct    232440
     ttggaattct aatttttgtg attctctaga acctgttgat gaagctgaac taaaaagaca    232500
     gttgttaagc tgggatgttt cacacaataa aaccccccaa aatagtagca acaagggtgg    232560
     aatttctaaa ttaatgataa tgaagagtaa tgggaaatct tcttcatata ggaaattact    232620
     tgaaaatttc aaaaacgata aatttaatag gaaaggatgg atggttatgt ttcggaagga    232680
     ttttgctagg cttatcaggg aagcaaaaat gaaaataaaa acaggttcat cggacagttc    232740
     aggttcagtg ggacattcta atgatggaga tggtgttgaa aaagttcaaa gtgaccaggg    232800
     aaccgaggat cagcaaatgg agaaggatca ggacactgtt atcaacgaag atagagttgc    232860
     tggtgaaaga aatttgccta acgaagattc aactgatgct gacttatcaa gagaattaat    232920
     ggacttgaat gaatatagta aagacccacc cggtaacaat taaggtgtgt atatgtaatc    232980
     aggcctgttt gttagcttgt gcacatttgt taattaataa tttatttaaa aatgggcaaa    233040
     atataaatgc ataaaagatg acatagagat atgtgcacaa agctatgtaa tcatatttaa    233100
     cattaatata tattatttcg ttattcacaa ttcgtcatga aggccagcgt agtttacggt    233160
     tcctgctact gcattatcat cgttgacaat gtttgtattc gaattattat tcaaaggtgc    233220
     tgcaattgtt tgcggagggg ccactggatt aggcaaagaa gtgatctcca cgttaagtgc    233280
     tgaaataact tcactagata gagagacgtc ttcggtaaca tctaccgtac cagatgcctg    233340
     catttccgtc gtaagcattc gggaaacagg agtatttaca ttttcgctga ttttgtggcg    233400
     taccccaaac gcttcagatg aatcttttga tgactgtact tctatcatta tttctttctg    233460
     tacaaatcct gatgcatcaa ttgaactagc agatattttg tgagggctac ttacaaaaga    233520
     tggtgctgtt gtggttacac ctggcatcgg ctgagctact gtgcttgacg cgctctccac    233580
     ggataaagtt cccttgccta tatcagacag agcgccaatt gaagcaccac tactactaaa    233640
     gatcatagat gccatagaag tcccttcaat atttgtggat tctgataggg aagattgacc    233700
     aacactcgtc ttaggtgatt gtacagcatc agtgaaaaca ctagtgggtt ccgaactgtc    233760
     agccaaaaca ctagtgggtt ccgaattgtc agccaaaaca ctagtgggtt ccaaattgtc    233820
     agccaacaca ctggtgtatt ccgaattatc aatcaaggca ctggagcgtt ctgaatcctc    233880
     ggtagagaaa gcaattactc tcgaagtctt cgtttctgtt tttgagaatg agctagttgc    233940
     cgtctccaca atagctgatg aaacaggttc agagatggaa tgaaatttag aaaaagtgga    234000
     atctgagatt gaagggattg attcagaagc aagaacagaa gaagttacag tcgatacttc    234060
     tattgactgg aagccagagg ttatagatga atcagaaaat gtactcggat gcgaggaaat    234120
     agagtcctgg gatgctgatg ttgacaaaat ttcttcattt gggatcaaat tagacgcaac    234180
     tgagtcaaat tcggatgcta tagaaataga atgcgtaggt gtttcaacca tacgctctaa    234240
     ttctgatgct atgggatcaa tttcggagac gggcgaagaa accatagtgt ctgtgggcgt    234300
     caacaacatt gaagaagatg ttgtaacata ctgctcggct tctgcattgg aatctgatgc    234360
     aggtatattc ctatactcaa tttttgtaat gacttcagtg attatttttg tcttataaat    234420
     ctctctcgtg gatgccggtt ttgagttgtc tagaaaagat gtgttggctg catcattggt    234480
     ggggtttgtt tgtgtggtgg taaccgcagt cgcggtactt gtggataatg ctgtagtagg    234540
     gctagttgtt aacgatgagg aaagagataa tgaagatgaa gatgaagacg gcatgtgtga    234600
     tagcgaaggt gattcagtac ttaagagttt tgaaacgctt tctctatctg ttgttatttc    234660
     gctttctgat tgttctacta ttaacgagga caatttctcc tccaagtcag gagtcggctc    234720
     aggatattct gtgatagaat ttgaagatga ggataacaaa tctatcgact ctgaattcag    234780
     tggaagcgat ggtttttcga caatattcgg ttctgtagga gaggctagcg gcttcgtaat    234840
     ttcagaggta ggtgaagaca caattggttc attagtgaca ctctcttcat agaaagaaga    234900
     agaagaagaa gaagaagaag aagaagctga tgttgggata tctgcagaag tgaattgtga    234960
     atcagctgat gacgatatcc aaacaaattt ttgctcatct tctgtggtgg ttctcatagt    235020
     gctagtgtca aatgaggaaa attcagtctc tatatcgcta gcaacatctg tagcgctgat    235080
     gatatctgca ctttcagtaa tgcctctgta atcgtcatta atagtgaaat aagaagaaga    235140
     tccttggtct atggtagtgt tttccttgaa tttcgactta tatatatcat gagcatgttt    235200
     gtaaataaag ccgtgcacat tatgtttgta gcctagttga atagcgccag ccaaaaccac    235260
     taacaaaaca aaattcaaga aaaatttcca aatatttcgt aaaattgatg acgatgtacc    235320
     ggaaagcttc agaacgttga tcgtgttccc catagaagtg cttgccaaat atctagaatc    235380
     tggagaaaaa gtaacttttg ttatagtaga ttcatgtact cttggaacca actgaacaag    235440
     ctttagcttt tcaacgctga cgatggcaac caagttatcg ttagatgata atgcaacgaa    235500
     cttcttattt ggggagacat ccatcgatgt tattccattc aaatcgaaca tgaaggatgc    235560
     tgtttttaaa attttaacac ctttggaact cacacctagt tttaacaagg aaactccatc    235620
     agagttcgat aatgatgctg ccactaatag cgtattgtca ttgagaaacc tgatattaga    235680
     aagaacaaga tttttatcaa aatccgtttt ccttgctaca aaatttccgt ccctaacaga    235740
     cgctacttcc aaagaattag aagtgatata tgacaaaaga ataccgttag gggcgaagtg    235800
     caaatcatta acttccctac ccgtttcaat ttcgtaattt tccgtcaaat tacgcgggtc    235860
     aatgattctt atcacagtgg gcacttcaga ggacgcaatt gcagctactg tggccctttg    235920
     attaatgtaa acaaacttag tgaaaacgga tgggtctgta gttctgttga aatcaatact    235980
     ggccacgaat tttagatgtt cttgttcaaa cacaaacttc ctcaagtggt ggttaacgtt    236040
     ctccatggag gaatcattaa acagttcatt gcaaccaact agaatcaggt tattattaca    236100
     atccaatgaa gtgggcgcat cgtcaatcga atctaatgtg atctcacgaa accttctaat    236160
     gtgtttcttt ttctggaagt tcacctttaa agctgtaatt ttgtttggaa acgaggaatt    236220
     gaactggcct ccaccaccag ccaccagtag agtgccttca tttataaatt tagcaccata    236280
     tatcggatat ccgacgtcat agtttgcaga gttgccactc attattatgc tagtttttct    236340
     aagtttaaaa ggagagaaaa aaaaggaaga gaggacgtat cgtagggaat tgtgatgctt    236400
     gttgacaaac agcctccgtc gatcgaagca gctataagcg taggttactt gaagcgttca    236460
     cagttctcat ttacactgta caattctcga gatataaatg aaaattacta caaccaagaa    236520
     aaaaggacag gagggctaaa aggataataa aatagggcag ttacaaatgt ggtcaaaaat    236580
     actagggctc aaaattgcta agtaagggct tgacagatgt aacataatac gaaataaact    236640
     ggatatcgtt taataattat caaggtgatt taaatcgtaa atacataggc tgggccatat    236700
     acactaacat gtgtcgtgac caatgtgcag cagatagact tgctcattaa atatattcca    236760
     ggtaggattc tctaagggtt tttttttttc tctatagctg tcactttttt ttttttctct    236820
     tatcaatcac agatataata agcataacat cggaaagaaa ataatgatag ggcaaaaggg    236880
     aaagcatttc cagttgaata cagtatctct actatattgt tgttcgctga agacagccgt    236940
     ttccggaaaa aagtgattgt gtgatcgcag ttacccgcac ctttgttcaa cagtacataa    237000
     taagaatctg tagatataga tgaactttct ctattacata agactagcct aaaagccttg    237060
     tttctatcat ttaaaggctt ttgagacact caaatcagtg tcaacctttt ggataagtca    237120
     aagaaagtac gccgctgctc agaaaattgt tatcgtgatt gagaactgat ctaggcatta    237180
     caattaaagg aaacaaggga aatattctat tgaatgttgc ataaaagccc ttcaagaaag    237240
     agatttgctt ctcctttgca tctaggatgc attctaacgc ttacagtgct ctgccttatt    237300
     gcttactact ttgctttacc ggattattta tcggtaggga agagctcatc caggggtgcc    237360
     atggatcaaa aatctgatgg aacctttaga cttaagtcta tctacaggca tggcgtcgga    237420
     gcaaaccatc ggctacacca gaggctggag gtcactccag aagttatttc tgccgctgga    237480
     atgctgtatc aagaaaccac aactcaagga caggatttcg aagaccaaga acccctatgg    237540
     actactaatg ccgaatatgc caccactaac ccattcgatt ttgagtttga gctacgaagg    237600
     atgccgctat tgatgaagcg gatgaaggaa agagatcctg aattcataga gtcgtacatt    237660
     tacggagaaa catacatgac ggaggaggaa gaacacgcca tgtggataga tgatgacatt    237720
     gtggcaccca atatcacaga tagaggtaca gtagtgtcgt tagcattaat gtcgtctaat    237780
     gcttacgtga gaataccgca aacgggagac tggcgtaacg tcacggagcc gtggaatgaa    237840
     acagagccgg aagattttgg ttgggatggt gatggtatac gtggtcacgt cttttacaat    237900
     gaagtggaga atatcgtggt actctcgata aagggaacca gcgctcaggg tttgccaggg    237960
     tctggcgaag atgagacaac tggaaacgac aagatcaacg ataatttgtt attttcgtgt    238020
     tgttgtgcaa gagtgagcta cctgtggact accgtgtgcg attgctatgt gaagtcgtat    238080
     atatgcgatg agtcttgcct ggaaaaggaa ctgagacgta aggatagatt ttactctgca    238140
     gtcgttgaca tatacaaagg cgtcctcaaa gaataccccg atgcggccat atgggtcaca    238200
     ggccactcac tgggaggcgc attggccagt ttactgggcc gcacttttgg attgcctgcg    238260
     gtcgcattcg agtcccctgg agagctacta ccttcaaaaa gacttcactt accattccca    238320
     ccgggacttc cctcatacat ggagggtatc tggcacttcg gtcacaacgc agacccaatc    238380
     ttcatgggta catgcaacgg agctagttca agttgctcac tggtgggcta cgctatggaa    238440
     accgcgtgcc acactggtag agtctgtgtc tacgatgtgg tcaacgacaa gggctggagt    238500
     gtaaacatgt tcaaccacag aatccacaaa gtcattgacg aagttctcct tggatacgag    238560
     caggctgcca agtgcgttga accagagccc tgcgtagatt gctacaactg gaagtttatt    238620
     ccaagcagag actgggaatc ctcatcgagg ctcattacca agactaaaag ccacgctgca    238680
     ccaaccacga cgactcgcac cactgctact actacctctt catctacctg tgtaggccgc    238740
     aattggcttg gcttctgcac caaatacgag ttgtaagacc catacatcta ttatgaccct    238800
     agtgttgttt tagggcctat gcgccctttt tttcttccat tgtctgataa ataatgtatc    238860
     attttgacaa cttaaaggtt cagctaaacg acacgagaag atatattaat actgctttaa    238920
     agtgaaaggc gtcagtcagg tgcaattaat aggtcacata ttctttgctt caattgctct    238980
     ctagcaaact cacacactcg tagattggaa gaccgaagaa aatagataga ctttcgaata    239040
     agttcagcaa caacatgtgg ttgaaatcct tgctgctctg cctgtactcc ttagtactct    239100
     gccaagtcca cgctgcacct tcatcaggga agcagattac ctccaaggat gttgatcttc    239160
     agaaaaaata tgagcccagt ccccccgcca cacatcgtgg aataatcact atcgaatact    239220
     ttgatcccgt ttcgaagtcg atgaaagagg cggatctgac ttttgagttg tacggtactg    239280
     tcgtgcccaa aactgtgaac aactttgcta tgctggccca tggtgttaag gcagttatcg    239340
     aagggaaaga tcccaatgat atacatactt actcgtaccg taagaccaaa atcaacaagg    239400
     tttaccctaa caagtatatc cagggtggtg tggttgcccc agatgtgggt cctttcaccg    239460
     tctatgggcc caaatttgat gacgaaaact tttacttaaa acatgacagg cctgaaagac    239520
     tcgcaatggc ctattttgga cctgattcta acacctcgga attcatcatc accactaaag    239580
     ccgatggaaa tgaggaattg gatggcaaaa gtgtcgtgtt tggtcaaata acttctggtc    239640
     tagatcaact aatggatgct attcaataca cagaaacaga cgaatatgga aagcctcagc    239700
     atgaattacg gttcctgtat ttcgttctag aaatcttaaa aattagtaac atcttagatt    239760
     tgcacgctgc gtacacagaa aaagtcgaga agtttagaaa tggcgatgtg tctgttggct    239820
     ccactttgga aaacatcttc cgtaacgata aagcctacac acctttaacc acctccactg    239880
     gaaccaccgc ctatgattta aaccacccaa tttccagagc cttgatgtgt ttaactgttc    239940
     ttggcctttg tttcattgcc tacaagggca tgcacgaaaa gcctcatacg gtttcattaa    240000
     gacacaagta agcaacttct tttcgatggc ttgatgacca catggctatg attttaatta    240060
     atatatatac atgacaatta tttttttata cattagcgat acctaaaatt tcttggttaa    240120
     tacccttttg acagcctcta ctgcattgcc cttgataata atttttttcg attgcatcac    240180
     cacagaccat gattttttgg gtatgaaagg cagttgctcc tgcaagtcat ttcttagttg    240240
     aattacatct ccttcaatct ttctgatctc cgtgataatc ttgttacctc catttttata    240300
     agcggaatac accggtagat ttccggtcct gcttctctcc acgtagtagg tctttttacc    240360
     aaaattgttg tttcctatga gctcatgcat cttcacgtct tccagctttg gaaatattgg    240420
     cgcctcagca gctttatttg aattagtgga tatacatctt atcgtttggt atatcgaggc    240480
     agtggcaggc cctggaaggc atttacccct accaaaacat ctagtaacac acgaactgat    240540
     catagttttg ctcacacgct accttggagt aagttgcttt aggtaaacgg gcacttcttt    240600
     caaaaggttt tccttcttgc tggagctata ctgcttatag taccatattt taaattcata    240660
     ccaagccatt cgtacgcgat gaccattata gatcgacctt gcgacaccat catatttaat    240720
     attcaaaaag aaaaaaatgc agttctatat cacagttata taatatttat atgtgcatgt    240780
     atgttacttg tctttgcaca taactcaatg cgtccacaat cttaccatct tgtctttccc    240840
     accactacac actcttttac cgtcgacact ccagtcgacg gtataaactt cgtctttatg    240900
     accagggagg tcaacagaaa gttttctagt tcttacatcc cacactttca acgtggtatc    240960
     tttggaacat gacaccagta gtcggcagtc cgatgaccac gcaacctggt atacgctggc    241020
     tacatgccct ctaaatgtgg agataaactt accatctcta ccgtcccaaa gtttgataga    241080
     gttatcaaaa gacgctgaga caatatacct accatcaggg ctgaacgcca catgattgac    241140
     taatttttgg tgaccggtca ttcttgctat aggcttggta gattttagtg ggttccataa    241200
     aaacatggta taatcatcgc ttgcagtaac catcatttct tctgaatttc cattcttttt    241260
     acagattttt tcataatttt ccaatgcctt tttctgggct tcttctggtg tagaaggctt    241320
     cttacctgta tgatcgaatg caccaatgcg caatgcgtaa tctgtagata aagataagtg    241380
     attaacccag tgcgcatgcg acttcaaaat gttgatacat ctgccctgcg aattgatgtc    241440
     ccatacacgt acggttctat cgtgagagcc actatacaat agaccttggc cgccccattt    241500
     gacacaagac actgaatttg tgtgaccact catcgtatac tggcaaactc tgctcacagt    241560
     gtcccaaatc ttaatagtac catccttaga agatgaagct aatcttggtt tggagcccgg    241620
     cttcacaaga tgtataggtt cccaacttaa agaagtgatc cacttggaat gacctctgag    241680
     agcatcacct agacactgac cgctttttgg gtcccataat cttatggtat tgtccatgga    241740
     tcccgtagca attacttctc catcggggga ccaggaaacg cagagaaccc aattgtagtg    241800
     accctttaga gtatgcattg gcgtttgggt gtcacagtcc caaatccttg cagtattatc    241860
     acctgcaccg gttaccatcc tagaactcgt atgtggtgcg aaggcagaac acaaaattgt    241920
     ggaaccgtga cctgcaatgg ctgatgaact tctagttacc ggcttgactt tgaaaactgc    241980
     tcttggcgta tacagtagcg tgatctgatc ttctgtactg ttatagcctg gttttattaa    242040
     tgaagaatat aggttatctg ttatatcaat cgtcttcaca gggtcactgg ccttcttacc    242100
     ttgaattgta cagctgaagg tatatggcac tggatcgtct gaagtaccgt tcaattgatt    242160
     taaaagttct tctaactgtt tctcggagat agcaccggga actctcaggg cgccacctac    242220
     attgtcacca gtatctaaag cttggaactt gattgaaaca ttgggtaaat ctttcggaat    242280
     aatagctact tctctgggaa gttgagcctc tttcttttgt ttcttagaag gtggaggaat    242340
     cagggtggac atctgtatat tgtgttagtg tgtgtttatc gaggttacaa atataaaaat    242400
     cttgtgatat atgtctttta aagatactct ttttgaagct catcgcattt tttttttttt    242460
     tttcatttta aaatttttca ccggtttctc gggtaacagc tctaaatgaa atcttgcctt    242520
     catcaccatt attgaattac attacattat atatcgtagt atatcatatt tttagacgtt    242580
     gaccactcta tgagcttagg ataggtactt gatctttctc tgagttgcca aatgctattt    242640
     cacggatttg tatcatccaa gggtctatca gtagttccac agcagtagcc ctcatagtgg    242700
     ggtcttgaac caaacacctt tccaagaagg ctcttcccgc tgcagtcatt tcgtctctat    242760
     tgggtagttg cggtattcga cctgcagcaa cgtggtacat gatggcccat tcattatcca    242820
     agttagacca aggtcgtcta cctgtggcca tttctagcac aacacatcct aatgcccata    242880
     catcgtccgc tccaagtttt cccttaactg ccgagcctga aatagtctct ggagccatat    242940
     acatcggtgt ccccatcatt tcattgaggg actttgtttc tactccaaaa tcttgaacgg    243000
     ctgcgttccg cacagttcta gtcctagatc ctacaacggt acgtgccgta ccaaaatcca    243060
     catattttat gattccattg aaatccagca agatattctc cggtttaatg tcgcgatgca    243120
     ccacgccaga ttggtgcaaa tatgccaaac cttctaatag ttcgaatgtg tacacttgtg    243180
     ttaccatttc atcttcaatt cttccatgat ccaataacga ggctaaagaa ccaccctcac    243240
     agtattccat gaagatgtta actttatcgc gatgtacttc gacaccatag tactggacaa    243300
     tattaggatg gtttaacatt tccaatacgg tcatctcttc tttaatcagg ggaaaaatct    243360
     tcttcattgt tgtggtatcg tgtatcttta tttccttaac agctaagatt tcaccgtttt    243420
     ccagattaat tgcagagtat acctgtccaa atgttccacc gccaatgaag cttctttttt    243480
     gccacctcat tgatacattc gataatgagg atgctagcga tagtaggtat ttgtttccct    243540
     gatctgtagc atccaatacc ttacccattt gcctgggatt cctcttcata gtcttttcca    243600
     acgtctttat agcttccagt ctcaacctgc tgtttatttc tagggtggcc tcttcatcaa    243660
     tattctcttc agtatcaata ttcaatcttg cctgttgcat gccattttca gcttcagtgg    243720
     ctcgtgcacc cataacgtcg aaatgtgaaa ttaataatga catacatact gataccctct    243780
     ccttcagttc ttgaaattgc tttacattca gcgccaggat attataacca ctagtcatct    243840
     gcatcgcaaa atccattgca agaacgcacc atcggaaagt tcgctgatcg gtaggatcac    243900
     actcttcaac aaggaatttc aaccagttca ttcctaattt aaccatcaga aagatgataa    243960
     cgtacttcct ctttgagcta aaggcgttat atttaaggaa acttcttcca aaatcccttc    244020
     caaacatgaa tatcgaattt aacaactcat ttcccggaca ttgcttcata aagctaccta    244080
     gaattccttt gtagttgttc aatactgtat aagtaagttt gtaatatgcc ttattgattt    244140
     tttgtaggga ggattcaatt gaattgagtg aacaacgttt ctctatgaat gaaacagaat    244200
     cacctaccgt ttgattaaac ttgtcgattt gataagtcag tgcataatta gaaccttgat    244260
     tgagtaaaat caacgtattt gggttaccaa ttttccctaa atccatttcg ttggatgcaa    244320
     aaaggttgtt acctggaagc ttatatactg gtccatccca aactactggc tctccaggat    244380
     atagtacaac tagtgcaccc aatgagctca aagcaacttc caattcaaaa acttcattgt    244440
     tcttttcatc aaggtgctga tcaaaagggt ctgttgaaaa attcttcttt ttggactgat    244500
     gagcatgcct gtccaaatca cttgacgaat ttgctactac tcggtagtaa ggaattcctt    244560
     tggaatcctc ccctttcgat actagaatgt tcaaatctgt ttcttttgtt gttatatcat    244620
     acacattcaa attatttcca atgtcaagct ttgggaccaa atcacagcca atggatttat    244680
     ttcgcaaaat tcttaagatg gtatcattgt cacaacctaa taattcagga gcagcaaaca    244740
     tatatacacc actagactca aaagtgttac cggagtatac caaaaaatag tgagcatctt    244800
     ttaacttttt aacaagttgt gcattatgat taatctgata aacagcagaa ttttggaacg    244860
     ccttgactag aatattgctg aacctgttca gctttctttt catggcaccc aaattttcga    244920
     aaatggaact tagccatttt tctgcttctg aagcgttagc aaatgttggt gggaagtttt    244980
     gttgtttcaa aagatagaat tgcaatttat gtacgagtct caaagttaac ttgagaaatt    245040
     catttggaat cacggtttct gcaccgttaa tatagtgacc ggtgtttttt aggtgatccc    245100
     agtatttcaa gagtagatcg ggtgctttga aattttgttt actggaatca atcaacttta    245160
     aattcaacag aaaaaataaa taacgaatgg cttctattac agtattttcg aacgtcgggt    245220
     caaaatccac atcgaacggc aaattggagc aatattttgt cagtgtgtac ttcaattgca    245280
     cagaaagtcg aataaaagcg ttaaaatcat cgatcatttg atcgatcatc atcattgttg    245340
     gatttttaag ctttcgtgca tatgacaatc tagtcaaaat aacttctttg attaaataga    245400
     cggggaacgc cagtagtgat cttaaccttt cataaggata ttttatgttc atctttgtca    245460
     aagtttctct gtagactata aaatgtagtt tcagtttgaa catccaaggt gatagcggat    245520
     agaaaatttt tttttggaat atagactcga tgttcttttc cttcatcaat tgttctgcaa    245580
     gaatcttcat tttgcagttc cattggggca caccatcaaa atcctcttgg caattatccg    245640
     aactacttat cggtgagaaa cggtttatcc agtcgtccaa ctcttgcctc ctcaacgtta    245700
     agttcgtttt aaagttcagc caagaattca ttacgtctat tctagcggta aattctgcag    245760
     tattggtgat tggtttatcc ttatacattt ttttcaagtt aggccaataa gagacaacgc    245820
     tgtgatatct gttcatgagg tcttgtaaga tggcctccag tgcatccagg ctcaatatct    245880
     tgccctgtgg aatttgaaac ttcattatct cttcaaaaac ggaatctgaa ctatctctta    245940
     aatatgtaag cgactgttcc atctcttgca tggtcctccc attcagccat gccttcaatt    246000
     cgagccatat ctcatctgag agctccttat ttaaccctgg tttcttgact tggttagcaa    246060
     tcctcgtctt ttcaccttta acaatatctc ccttcagcac tctggccagc attgactgcc    246120
     atttgaaccg ttcggtcgca atttcattcc aagctagttc atcactgtct gacctcattt    246180
     tcctgcaata aggtgtagtg gagaaaaact tgacacctga gtgcaggtct tcatcaattc    246240
     tgtcgccatt agacaaccga ataatttcgt catcaccgtc gtcttcctcg tagcggttag    246300
     tgagttttat gcccctcgtg tagtagtcat ctaaagcggt cttttttagc tttttcaagt    246360
     atagcgattc attgaaaacg tatcggtcct taaaagtcag ctgactgggg ccgtcgctta    246420
     ttgtttccga gccacccaat gctttcaaat cagatcttga tagtttatgg ctggaatgac    246480
     ttgataatct cttcacgagc ttacttgaga tggtatgagg agccagaact ctcccgcctt    246540
     cagccgcttt ttgttgctgt gtattcagta tatccatcat cattttcacc tacaaggaac    246600
     taccttttat agccacccta agtaaaacaa cattagctta gcatcctcaa ttcttatcgt    246660
     atgttgttgc tgctattttt atcctattgt tcctggcatc gcttttttac ataaggtacc    246720
     aaggcaagag aaaagacccg cgaaattttc aattcgagac atagggttaa tacgaaatat    246780
     gttaaggtct agtttccaaa aaatgaagaa aatgtgatta gacatcctgg ggaaattagg    246840
     tttaaatagg gcgggcgcta caggggtttt cctaacaaat ttcaatgata atagtggcat    246900
     catcatcgtc atatccagtg taggtatgga ctagaacaga aagcaatttg cagcaagaca    246960
     atatgactac gacggtaccc aagatattcg cgtttcacga gttttcagac gtggcagagg    247020
     ccgtagctga ccatgtagtc cacgcgcaag acggtgcatt ggctccaaag aacgagagga    247080
     aacactctgt tcccaacatc agcatgaatg cactggatat gacgagagag gcctcttgca    247140
     aaagcacagc atctgccgcg gaagggaaaa gtggtagcag tggtagtggc agtggtagca    247200
     gtaagcccaa aaaggagaaa cggttcaaga ttgctctctc cggtgggtca ttgatcgaag    247260
     tgctacacga aggtctgcta aaacgagacg atgtacggtg gggagactgg gacatttact    247320
     ttgcagacga gagacttgta cccttcagct cgaatgaaag caattatgga tgcgccaaaa    247380
     ggaagatttt ggacctgata gacacggcga agtatggaac tccgaaggtg taccacattg    247440
     acgagtcatt gattgacgac ccgcaagaat gcgctgataa ctatgaaaag gtgctaatcc    247500
     gcgggtttgc cggtagagat tccgtcaaac ttccgatgtt cgacttgttc ctgcttggtt    247560
     gtgcccccga tggtcatatc gcatcactct tccctaactt ccaggacaat ctacgtgaga    247620
     aacttgcatg ggtggtgccc gtggagaacg ctcctagtgg gccctcgacc agaatttcgc    247680
     tgactatacc tgtaatctgc cattctcaca gggttacttt cgttgtcgaa ggtgcaacca    247740
     aggcgcccat catcaagacc attatggaaa ggcctgaaaa gggcctacct agcagtattg    247800
     tcaacgaagg tgctgctggt cgtgtatcat ggtttgttga cgacgatgct cttacggacg    247860
     tcctcgtcac caaaaaaaag tataaattcc accaaggttt gtctatttaa accatgcatg    247920
     tgtgtacata catacataca cacatacata catacataca tatatttatg tatatttatg    247980
     tatatatata tatatatata tatgcgtaat tatgcagatt tctccttgtg tgctacagcg    248040
     ggtactctga cgccagatca tggcctcgag atcgatatac aaaccactgc atgataaaga    248100
     tgaagttgaa tattaaagtt accattgaca gtcccacttt tccaaaattt gtcacgaacg    248160
     tatccagact gaaaccttga tcgttagaca actgccaaat caattggagc agcgaggcga    248220
     taccgccagt gacatctaga aacacaccct gaatggggaa acaatccata gattttcttg    248280
     tcgagttatg cgtcacttgt gggatgtact tgattagtga catcgatatt ttgagtaaaa    248340
     acaaattgtt gcaatacgcc agagttcttg agttatgcca atcgtaccag tagttggagt    248400
     acataaattg tacggttagc agtgaaaaaa tggccagtga tgcgagtaaa atccttaggt    248460
     accatggatt catcttgcgg tgacctttac ctggaaatcg ccagattctc gctccagcta    248520
     ccacctgggt caataagaca acattcatca agcacccatg caggcaatac cagaaatcaa    248580
     attgcgtcaa cttgggcctg cccaagtcag actcatcacc cgtcattttc cagcagtaca    248640
     attgcaaaaa tatggatatg accaggtaag agtaacctgc cgtatttaac atgacaaaat    248700
     ccatcgatat cgcgctcgct gacttatggc gccaattggt gattatcggt ggatacatcg    248760
     atatcgacca tgacgtaaca tacacgatac ctagtatatc gtctaacgac accattttgc    248820
     ttcgcgtttg cttttgtttg cttttagttt ttcttccctt gtttacatat ggaaactcac    248880
     cttaaaattt caagattatc aaaaaatata aaggattccg ctattaaagg gcaataccac    248940
     aacctcaaac caaatcacct aaaccaaatc aaagatggaa gcggaaaaac aatctgatat    249000
     taagggaacc attgctttcg atactcacgg taacgttata gagtctaccg gcgtgggcag    249060
     tcaaaggatc gaagatatcg gtgatttatc gaaagttacg ctggatgcag aaggttttgc    249120
     tcaagttcaa ggagattcgc tactcgtaca cctgtacaaa cgcaatgata tcactttagc    249180
     tgtatatacc agcgctcaat aaattctttc cttccctttc gacatagcta tgtctgtata    249240
     ctatctaaaa actaaatatc acaataaaca aagtactaaa ataaacaccc atttaaataa    249300
     agccagatcc tgaccctcca aatccgccgg atcctgaacc tccaaatccg ccagatccag    249360
     gaccaaatgg ttcgtcgtac ttggatccag gcatccatcc tggcggcata tcttcccgtc    249420
     ttggggcagg tcttctattt ggatcgaaaa tcataccgcc ttggctactt ggattcccca    249480
     gaggattggg aagccctcca gaccaatccg gatggcttgt gccaacagga tacagatcac    249540
     catccgcata ccctcctgct gggttagcga agctcggttc agttaccgta agtccgggat    249600
     atgggttcaa cggtgctgtt ccctggtttt gtcttgcttg tgcctggtac tcatcgtcaa    249660
     attttggcat gtccgcacta cctgcagttt gtcttttaag ttgtgtcatt ataggtttca    249720
     ggtctggctc cacaggtaag ctttctcttt ctagtggcca tttcaattct gtgggcaatt    249780
     taaaatcgct gtaacccacc acacatgcca tggtgatcga cgtaccatga cgaataacaa    249840
     cagtatactt gtcattgtca tccagagtct gaatcaccac tagctcagag agaaacgatg    249900
     ttgaaccctt ctcactggga gaatctttaa tgcgaaaact cacttggcat gatttggttc    249960
     cctctgtatg gcgtgacacc acctcagttt taccgatgga ctccaacact agttctgcta    250020
     ccagttcaac cttattctca atcattgttt aactcttgcg ttactatggt ggtattattg    250080
     atgctaatac gggtttttta tgaaaaaaaa aggataacaa acttatataa acttatataa    250140
     aaacatatac aataaatgat ctacaaaggg taggaaataa aaaataaggg agaaaaaaaa    250200
     atacatgcgt aagtacatta aaattacagg aaaaatctta ctttagttct gatatttcac    250260
     catcgcgata caccaacccc ataacgttta ggaacaaatt caaatcttgg tatagtttct    250320
     ctttattata aataatagat tttaactctg tgtctaattc ttgagacctc tgaggtaata    250380
     cactcaattc tttctctttc ttttgtaagg tctccgcctc gttaatagtg gcaaagattt    250440
     catcacgtac ttcatcaata atgattctct ggtggtttag ctttccactt agtgctaaac    250500
     tagctaggaa ctgccaaatg tatgcttcat ccataaactt gtcattttgt aaacgcatga    250560
     tgtggtcgtt atattccctt ggagggaaaa tcagctgaat cttactttcc aatgaagtga    250620
     ataatttatc ataaatctca ttccatgtgg agatttcagg agaggaaaga atattagatc    250680
     ttgatgaatc ttgcttgatt aatgcggcac gagaaatcaa aatggtgatc aaatttagac    250740
     caattttgga ggtggtcaag aacgaaacgt tgttgtttct gattaactgt agcaacagac    250800
     ccataatttc gataaaattg gagttattag acaaaaacga gacaatgatc tttaatatga    250860
     tcatttggaa cagatcgact ttcttcaatt gtgtcaaagt tggttttggt gtagtcttgt    250920
     aggaactcaa tatgatgatt tgcaagtgtg ataattcatt gaagattttt tgcaggattt    250980
     tcaatttttg ctgcttatcc aagaaattaa aaattctagg cataatcttg atacctttat    251040
     caaatgatag catcgaaatg aaagggttta cgtcatatga actgtcgtcg atgtgaaggg    251100
     cctcccacat tgcagtgctg tcagtttgct ggccattcct caagttagct tccaagtcta    251160
     aaatctcttc ataaactgtt tcaattaact caagaatgaa ttttttgccc ccagatttgt    251220
     tcaaatttgt ggcaccatta ccgttgttga acgcgtatga agatcttctt ctttgcttag    251280
     aagcaacagc agcggcagaa gagcccgtag aggaggaccc tgaagaggcc aagtccacgt    251340
     tggtcagaga gtcagtgacg tcttttagcg catcggggtc agaaggctgt tgtctgggga    251400
     tctgcagttg tcttcttgga ttcttgctgt tcaaagtgga agagattttg cccagaaccg    251460
     tgtttgcttg cttattatcc tggctagagt taccagcagc cgcttgttga tccttcaact    251520
     tagaaggtct ttccttagcc acagtgacag ccttttctac ttgactttgc attctctgta    251580
     gggcaatatc ggttctctta tagcgaccac cgagtctgtg tccagaatgt tccaaatacg    251640
     ccctagcaat caaacctttg ttggattcgg acgtgatacc gcctctttgg ataatcttgt    251700
     agacctggaa gtagaaatcc tcattgtaag ggtcctcagt gacaatttga gacaactgat    251760
     atctggtgat gaagtcctta tcacgaggag tcattaaacc tgagtatttc aagattttct    251820
     ccactttggc atgacgaatc tgcaaacgtc tttgctcttc aggcgacaaa tctctcttcg    251880
     atctgcgtcc actttgcaga ggcattttag ttgcgccaac cacagggcct ggagaaggag    251940
     tgttggacat accgatgggt gaaggcgaag cttgaactgg aacttgtaca ggacccattg    252000
     gcatttgatt catattcaca ttaacgccag gaggtggagg tggaggcgca aattgtgagg    252060
     gacctggttg acccgacgca ggctgcattg gaaattgctg ctgaggcgga ccctgtggga    252120
     gaccctgtgg atgacccatg gcgtggaaat tcataaactg ttgctgcatt tgacgttgtt    252180
     gtctttccaa gtcttgcatc gacaagattg gctgtagggg ggccatttgc tgcggagcag    252240
     gagccggagc cattgtactt tggggtgaag gcgccattgc tggaggtggt gcagtagacc    252300
     acaaagattc cattggcttc aggtctagag gtcctgctgc tgccgttcca tcggtcctag    252360
     ggccgctaat tccttctgca gtagctgcaa catatgatct agccgtggca ccgacgccat    252420
     taccaccaat tgcgttgccg ctgctgccgc tgctgtgagg atttccaaaa tcaaagtcgg    252480
     taccaacctg aacattatca ccaaatgttt cgtcgttcaa atagtcgttc tcctcaagtt    252540
     cgtgctcgcc atagcccttg taactctctt caaagtccag aggaccatcc cgcgcattac    252600
     cgctattttc taacccaaag aaggacattg ctagtgcttc ttgctgctct tacttccggt    252660
     taaaaccttt gcttccttca aggtgtacat gtttcttttc attcaccttg tttctttctt    252720
     taaaaagagg aagaggaaaa aaaaaatttc gtgtaatgcg agaagaacaa atagggaagt    252780
     gataacaata gtatcaataa caggctgcaa tcggggcaat taagcatcag aagaggggaa    252840
     tttgatgcgg ctggggaatg cttatgcgta ttgcaagccg tcgcaaaatg ttgggctgaa    252900
     gctggacttg ttacggggtc ttccagggta cgtgggtcac gccacgagta ggatcaaccg    252960
     gttagagaac caggacaatt actccattaa aatgatgcgg tcgtggccta atgcgtatgg    253020
     aagtgccctg aactgctctg tattcgatgg ccatggggag aaaggtgcgc aactgtcaca    253080
     gttgttagcc gataaattgt gcagtagcct ggatttccct gaaccctcct gggacaagca    253140
     ggacttgaag aagttggtac aggaatatgc aagaaggttt cccgagggaa attactggaa    253200
     acataagctg tccacgtttg aaaaattcta caacaagttt ataaagaact gcaactcgaa    253260
     acaagaactg ctgctgatga aggagggcga tagtgcgatc cttggacaaa atggtggcag    253320
     gatgattttt gataaaatgg ggaatattat tgacaaaatt gcactgctca ctgagctaga    253380
     ccgtctgcga ttgttctacg ggtttgccag gttcgatctc gaccaatgct gcggcctggg    253440
     caccgcagcg gggtccacag cgtcgtccat atttctatat ccgtatgatg atccgaatgc    253500
     acccattgat gaggggaaag acgatgactc gtggatcata tcgcactctg gattgctcaa    253560
     actcattgtc acgcaggtgg gcgactctaa gatcatcctc tgcgatcaag acgggattgc    253620
     acacgcatta acaacaactc accacatcaa ttccagtagg gaacgacacc gtttgagcat    253680
     agacccttct cgattggacc cagacgcctt tggagagaca aggtttttga ataatttcgc    253740
     caacactaga tcgtttggtg atgtcgctgg gaaaccgtat ggtatatcta gtgagccgga    253800
     tattttctcg tttcttgtcg gaaatacctt gcatttgccg cgatctgaaa ggtcgaagct    253860
     gcccttcaat ggtgatgaat gcttcctggc gcttgtcacc gacggcatca ccaataaact    253920
     tgcagaccaa gaggttgttg acctcatcac ctctacggtg aactcctggg gactgaaaaa    253980
     ggcgactcct caatttgttg cagaggagac aatcaaattt attcaggcaa tagccactaa    254040
     acactcagac aacgccactt gcgtggtggt taggctttcc aattggggca actggcccaa    254100
     tgttgacaga actggccccc aaagagaaac caaactaatg aatgcacaat ctaacgaaac    254160
     aaaattaaac taaacacccc cctgggtgga aacaagtcct agataatcat cttttgtatt    254220
     ttttttcttc cttttattag tatgtataca tatatattac tttttatatt ctttatagcg    254280
     cattttaaac acctttctga aaaaatgctg agatttttga tgctaatcga aagattaaaa    254340
     aaaggtctat agaggtaagc caataacgcg atgaataacg gttctggtcg atacttgctg    254400
     actcccccag atgatcttca cccctatgtg ccaagctcga aacctcagga acaagtatac    254460
     cctgatttca agccttggga gcacactgca gcagaagatc aaatcctagc aaactttgtg    254520
     gctaagggct tttaccatac accaatggta aatttcgagt ccatatctgc gagatcatct    254580
     gttcatgaat cattagtcac tcaatccaac attctttccc agcaattcga caaaattatc    254640
     aagattagag aagaccacat taataagatc ccctcaaatt ccacgacgac attacacggg    254700
     cctggttttc agttgcctaa tagaataacc cttactgatc atagaaagga aacgtggttg    254760
     catgaattga gttcgtctca cacttcgctg gtcaaaattg gcaagtttat acctcacggc    254820
     ttgaaaagaa ggcaagtcat cgagcagtgc tatttaaaat ttataccatt gaaaagggcg    254880
     atttggttga taaagtgctg ctattttatc gaatggaaat cgaaccacaa aaagaagagg    254940
     tcaaatgctg ctggggcaga tgatgccatt tccatgcacc tgctaaagga ctggacggat    255000
     acctttgtat acatcctgga aaagctcatc tttgatatga caaatcacta taacgattct    255060
     caacaactgc gtacgtggaa gaggcagatt tcttattttt taaaactttt ggggaattgc    255120
     tactcactaa gattgatcaa taaggaaatc tttcatcatt ggcttgtaga gtttataaat    255180
     aagatggaaa acttcgaatt tttgccatta tctttacata ttttgatgat tttttggaac    255240
     gacatctgcc aaattgatac aaatgctcct gttgcggcta caataacatc aagtcaaaaa    255300
     gagcccttct ttctggtaac aaaaatcact gatatgctat tgcacaaata ttatattgtt    255360
     tccagcagca aatcaatgat aaatgacgag aactacatca tcaatgatat aaagaaaaac    255420
     aacaagataa agttgaatat tctcaaaata ttatccagtt taattttgaa aatttttcaa    255480
     gaacaatctt tagaggtgtt tatatttccc acatctaact gggaaattta caagccctta    255540
     ctttttgaaa tagtctcaaa cgccgacact aatcaaaatt ctgatatgaa gaaaaaatta    255600
     gagttaatta gttacagaaa cgagtcattg aagaataatt cttctatacg aaacgtaata    255660
     atgtctgcca gcaacgcaaa tgactttcaa ttaactatcg tcacctgtaa acaatttcca    255720
     aaactatcat gcattcaatt aaattgtata gatactcagt tcaccaagct actggacgat    255780
     aaccctacag aattcgattg gcccacttac gttgaccaaa atccccttac aatgcataaa    255840
     attattcaat taattctctg gtccatacat ccatcaaggc aatttgatca ctatgaatct    255900
     aatcaactgg tagcgaaatt attactattg cgaataaatt caacagatga ggatttgcac    255960
     gaattccaga tagaagatgc catttggtca ttggttttcc aattagccaa aaatttttcg    256020
     gcccaaaaga gggtggtatc atatatgatg ccttctttgt atcgcctgct taatatacta    256080
     attacttatg gcatcattaa ggtccctacg tatatcagaa agctaatcag ttccggccta    256140
     ctttatctcc aagattccaa tgataagttt gtgcatgtcc agctgttaat taacttgaaa    256200
     atttcaccgt tgatgaaaag tcaatacaat atggtattga ggaacgttat ggaatatgac    256260
     gttaaatttt atgaaatttt taatttcgac caactcgtgg aaatcacaga acaaatcaaa    256320
     atgcgaatac tctccaatga tataactaat ttgcaactgt cgaaaactcc tctgagcatt    256380
     aaaatcatgg ttgcagaatg gtacttatca catttatgtt ccggtatttt atctagtgtt    256440
     aaccgcacag tgttgctaaa aatattcaag attttttgta tcgatctgga ggttttccac    256500
     cactttttta agtggatcga gtttattgtc taccatcaat tgctaagtga tatagaatct    256560
     ctggaggcat tgatggacat cttgctatgc taccaaaaat tgttctcaca attcattaat    256620
     gaccatattc tttttacgaa gacgttcata ttcatttaca agaaagtttt gaaagaaaaa    256680
     gacgtgcctg cttataatgt gacttcattt atgccattct ggaaattttt tatgaaaaac    256740
     ttcccttttg ttttaaaggt ggataacgat ttaaggattg agttacaatc tgtttacaat    256800
     gatgagaaat tgaaaactga gaagctgaag aatgataaat cagaagtctt gaaggtgtat    256860
     tccatgatca ataattcaaa ccaagctgtt ggacagactt ggaattttcc cgaggtgttt    256920
     caagtaaaca tcaggtttct actacacaac tccgagatca ttgatacaaa tacaagcaaa    256980
     cagttccaga aagcacgaaa caatgtcatg cttttgattg ccactaactt gaaggagtac    257040
     aataaattta tgtccatttt cttgaaaagg aaagacttta ctaacaaaaa tttaattcaa    257100
     ttgatctctc taaaacttct aacttttgaa gtgacgcaga atgtgttggg gctcgagtat    257160
     attattcgat tattaccaat aaacttggaa aataatgacg gctcatatgg tctgtttttg    257220
     aagtatcata aagaacaatt cataaagtca aattttgaga aaattttact tacatgttat    257280
     gaattagaaa aaaaatatca tggcaacgaa tgtgaaataa attattatga gatcctattg    257340
     aaaattttaa taacttatgg gtcatctccc aaattacttg caacatctac aaaaatcatt    257400
     atgttgttat tgaatgatag cgtggaaaac tcatctaata ttttggagga tattttgtac    257460
     tactcaactt gtccgtcgga aaccgatctt aacgatattc cattgggtag tggacaacca    257520
     gacaatgaca ctgttgtaac caacgatgat aaaagtgacg atgatgatca cacagtcgac    257580
     gaaattgatc atgtagaata ttacgttatg atggactttg ccaatctttg ggttttccaa    257640
     gcgtttacct gtttctgcat caaaaaaatc atggagaata atgagccagc aatggcaatg    257700
     gaagacttga agaacttcat attccaaatt atcgaaataa ctaattctaa tgatttatgt    257760
     tcacaaatat ttgaccaact gaaggatatg cagaccattg agatgataac ccaaatagtg    257820
     gagaaagatt tctgcacttc ttgtttgcaa aacaacaacc aaaagataga tgataattac    257880
     atcgttgtgg tgatcgagat tataacgtca ttatcgatga ggtttcaaag agaaacttct    257940
     ggtatgatag ttatttccat ggagaactat catttactaa taaagatcat aagacaatta    258000
     agtgaactga acgaaggaaa tttatctaag agagaaatcc aaatagatgc cgtcttgaaa    258060
     atttttagct ttcatcagga ttccattttc caacgcatca tcgctgattt atcagctgat    258120
     aaacccacaa gtccattcat tgatagcata tgcaagctgt ttgataaaat atcatttaat    258180
     ttaagattga agctgttctt gtacgaaatt ttgtcttcat tgaaatcatt cgccatctat    258240
     tcatccacaa ttgatgcccc agcattccac acaagcggta aggtcgaact accgaagaaa    258300
     ttgctgaact taccaccatt ccaagtgtcc tctttcgtta aggaaacaaa acttcatagt    258360
     ggcgactacg gggaagaaga agatgcagac caagaagaat cgtttagttt aaatttagga    258420
     atcggcatag ttgaaatagc gcacgaaaac gaacagaaat ggctcattta tgacaagaaa    258480
     gatcataaat atgtctgcac attttccatg gagccgtacc acttcatctc caactataat    258540
     accaagtaca cagatgacat ggctacaggc agtaatgata cgactgcgtt taacgattcc    258600
     tgtgtaaacc tgagtctttt tgatgctcgg tttgagagga aaaatccaca ttgatctcag    258660
     aatatatcca aatggataaa ttataaattt accaataaca gtaattatgt gtcagtttta    258720
     atacccaacc aattgattcc tctaaatgat accgtaccaa atgacatgtt tgccaccgat    258780
     tataaaactg gggtttatga gcgatggtta aggaggatta agacaaagtg ctcatccgct    258840
     tacaagatca gtactagcgt gtaccagtct atttaaactg gaatgatcac cccaaaggga    258900
     acgcacgatg ctgtggccaa gtttcaaaaa actgacctgc atcaagatct cgattacatc    258960
     gtactgcaac aacgaagaac acagctagag acgcttatta acgaaagaga atcttttgtc    259020
     aagaatctgt gttctctttt ccacaaaatt caaaatacca agaattacca ggaatttgtt    259080
     gatgtattgg cggagaatag ggatttactg cgagaaattt tcactgtaga gaacggattt    259140
     caaaagcaaa aatggattag caacgacgac attccccaga tagactggga caagtttgcc    259200
     ctagatatca acgcttatat agcagagaac gatcaattgt tggctttgta tgaagatggc    259260
     ttattatgat caaatagcgg ctatggacat ttttaaacat atatttatat atatatacat    259320
     atatgcgtat attgcataaa tcacaaagaa gaacaacgcc ctagatatag tgacccaaaa    259380
     tattatgttt aagttactgg ttggggttca tgtacatttt tcactatctt ttaattccaa    259440
     atgtggattg tgcttctgca gattttgttg cctagtattc tgtgatggaa aaaattgccc    259500
     cgatgagata taaaatgagc tagcccccta accaaagaaa gcaggattgg ttagtacata    259560
     gagaaaccaa agctgttatg ttgttctata agcctgtgat gaggatggcg gtgagaccgc    259620
     taaaaagcat aagattccag tcctcataca ccagtattac taaattgacg aacctaacag    259680
     aatttaggaa tttgatcaag caaaatgata aactagtcat cgatttttat gctacttggt    259740
     gtggcccctg taagatgatg caaccacact taacgaaatt aattcaggct tatccagatg    259800
     taagatttgt caagtgcgac gtggacgaat caccagatat tgccaaagag tgtgaagtga    259860
     cggctatgcc cacctttgtt cttggcaagg atggccaact catcggcaag atcattggag    259920
     ctaaccctac tgctttagag aagggaatca aagatctata aattttatat tcatgagcac    259980
     atgtagtttt ttttttttta gttttaaata taagaaaaaa gatagtatat atatatatat    260040
     atatacatat acatataaaa ggaaagtaag cttatacaat acacaaataa attcatatca    260100
     aagaataatg aaccgcaata ttcagaaaca caggaaaagg aggggaaggg atgaatggtg    260160
     aggaaagtaa ctgtttgttt taaagcgtac ctggatcata acataacaaa taagtagata    260220
     aaaaagaata gagagaaaga tataatgaca atgaattgaa gaatagttta gttagttaca    260280
     tttgtaaagt gttccttttg tgttctgttc ttaatttggc gctatttttt tatacttcca    260340
     aatccttgct ttacaatcac cgctaccagt agcaaaaacg ttatattctg gacccagcgg    260400
     agacccgttt gccacagcca cagatataac tgaattccta tgaccttgca acatcaataa    260460
     cggattgccg gatttcttat cccaaaacag gacaccacga tctttggaac cggacaagat    260520
     gtactcatca ttttgtgtgg tggccacgga caatacaaag tctttatgcc cgatatacgt    260580
     aacttcacaa gtgccggaat ttggagtttt cgaatcgctc ttgttgtttg cattctgcaa    260640
     attccagagc ttaacagatc tatctaatga gccggataca acgctttgtc catctctagt    260700
     gaagacaacg ctataaacag agtccttgtg gcctgtaccg gattcgtttt ccgaatctag    260760
     tctttccacc aagaatccgg tctcggaatc ccaaactctc acagcacgat ctagagaacc    260820
     agcagcgatg tatttaccat cacctggtga tacagcgacg gtggtaacac catcttcaat    260880
     ggataaagtc aatgaacact ggcctgtacg taagtcccaa atacgaacgg tacggtcacc    260940
     agaaccggag actaatttgt cacctgaggg aaagtagtcc aatgaataaa tatcttgttc    261000
     gtggccttga agaatcataa caatctttct attttcaata tcccaaattc taatcagtct    261060
     gtcttcagca cctgttgcca aaaatttccc atctggagaa aaacacactg aacggatata    261120
     caagtcggat gatggggaag acgaagtgtt caggttttcc acatcttttg ccaattctgc    261180
     tgccgaagtc atcgctgtgg tagtaattgt ggtggtagta gtggttgtca ttgtattgtt    261240
     atccgtggac gtggtggtgt tattttcagt gatcgaattt cgatggttat tggcagcaga    261300
     atcgtcagat agacgggcca ccagagaacc atctgaaacg cgatacactt gagtagtttt    261360
     gttgcagcct gtggctaagt attcaccatc gttactgaac ttcacgcaac aaacaactga    261420
     agtatgatcc aaagatttgt gtaactcaac gtcaatttct cttggtagtg ccgggttgta    261480
     taaaatataa taatcatttg tttgcttctt cagagcatcg ggaacagact gggaatctag    261540
     atccaaaagg aaaggtggga taggtttaga gtggtttgct ctttgattat aagggactaa    261600
     gtagtgatcc tggtgcaaac tagccggggt ggcgtcttcc tccttaggtt tgatttcagt    261660
     ttcagttgcg gtggtagtgg tggccgtggt ggcggatccg gtgtcattta tcttcgaggt    261720
     attattattt tccggttcag tttctttcaa cgtagattca ggtgccttga cagagggtaa    261780
     agtagtggtc tctttagaag taggagatcc gttgatggct gtgttactca atggtgccac    261840
     ggaaacctgg ggaggtggtt gctgttgttg aagttgctgc tgttgcagtt gctgttgtgg    261900
     tagttgttgt tgggcgtttg aggacaccac aggcaaagtg gtggtaggca actgtgagcc    261960
     aaccagatta ggacggctag cttgtactgg gaaggccgat ggcgaaccag tagttgtgtt    262020
     tgctgctgga gtggcggtgg ccgaagtagt agccggtggt tgttgcgcaa ctggaacaga    262080
     tgcagatgca gcggctagct gctgctgttg ctgttgtaaa tgctgctgga cctgttgctg    262140
     ctgttgctgt tgccgctgtt gctggacggt caaagatgca atttgatggt ctctttgctc    262200
     cagccctagt ttcaagtgct tgatctcttc ttcgtacgcg tccttcattt tcctgtgagt    262260
     tagttccagt tcgtagacgg tgtttcttat ctgctgcatc tcagccagct gctggttcat    262320
     tttgaaatcg taatcctttt ggttttgaag acggtaggta tttgcctctt gtgagacttg    262380
     gagaaactcc tgtctgatgg catcgagaag ctcattcagc ttattctgcg tattcgaaac    262440
     gctggcagtc atattggttt ggatggaaag ctgatttctt tcttcccctg cttatcaaaa    262500
     aagacaaaaa aacaatagaa aaagagtagt ggtgtgcgaa aggtaacttg gcgtgaaaga    262560
     aaattaaaca attgcagaag gacagataga ggggcacgtg ttcagccagt tgttcttgct    262620
     tcgctgatgt ttatcaattg ggggtagatg ggggaatttc tctctatttg tttacttatg    262680
     tacttgttat tttgttttgt tgtttgttgc tttgacggga gagcttttta attttttcgc    262740
     agtttttcag tgttttttga aaagtacgaa aaattaaggt ccgtcggtag cgataatgta    262800
     agagggttct gtctctaaaa atgttagggt gaaagttcca aaaaattatt aactcctaga    262860
     ttgctcagcc aaaaagaagg gtaaattagg gctttcctgg tttatttatt tgtttatgtt    262920
     gttcttatat acatatgttt atgtcttttt atgtacaaat aatgatgttt acaatgaaac    262980
     atctgttatg ctatcaaaaa cgtcagcgca ttgttttata gctgaagaag ttacaacgga    263040
     taacggtctg atttgcggcc tggcaatgct tggtaaaact aaatatcaat tttacgaatt    263100
     atttactgta tatagtattc agtccctcac tcaactggcg tcaagagtga agaagggcgg    263160
     cctcattatg gctcgcctta ttctgttcac cctctgcgct cttcccgtat tatttcattt    263220
     tattttgttt atgcttcaat atcttgtatt tgtttacatt gaaaaatgat tggaaaaagg    263280
     tcacattgaa atcaaaacag tgaagaagca gacagacaag aaggtcatta gatagataaa    263340
     caggaacaat aaaaaaaaga aagcgaaaca agacaatcca acgtgcgcaa aatggatcca    263400
     ttgactgtat acaaaaactc agtgaaacaa cagatcgatt ccgcagactt actagtggca    263460
     aatttggtaa atgagaattt cgtactgtcg gagaagctgg atacaaaagc aaccgagatc    263520
     aaacagctgc agaagcagat agactcgcta aacgcacaag tcaaggagct gaagactcag    263580
     acttcccaac aggcagaaaa ttcagaagtc ataaaggacc tttacgagta cctctgtaac    263640
     gtacgtgtac ataaaagcta cgaggatgat tctgggttgt ggttcgacat ctcgcagggc    263700
     acccactcag ggggatcttc cgatgattat tcgataatgg actataaact cggatttgtc    263760
     aagggccagg cccaagtcac agaagtcata tatgcgcccg ttcttaaaca gcgatccacc    263820
     gaggaactat actcgctaca gtcgaaacta ccggaatacc tcttcgaaac gttgagtttc    263880
     cccctctcgt cgctaaacca attctataac aaaatcgcta aaagcctgaa taagaaaaga    263940
     gagaaaaaag atgaaaccga gtaagctgct acataatgtc tatatatcta cacataaaat    264000
     tccgattatt cctttgcata cctgatttgc ccctcagaat ccacaaccag acttttcaag    264060
     aaggtctttt ttgccccttt atccttcatg gttttcaaaa ttttgtacaa cgacttgccc    264120
     ttgtgaagct cgataccgtt cgaggtcttt tccactttct ctgccttctt gatcacaggc    264180
     ttctccactt tctttgcagg agttgccact ggctggtgct ggtgctgctt ctgctgctgc    264240
     ttctgctgct gcttctgctt ctgcttcttg ttgcccttgt acaacgcttt ctggtacttc    264300
     tcgtcctcgc tgatgcaaga cgtgtgattc ttgtaactca cgccatcttc aaacgtcttg    264360
     gagcaatcta tgcatgtata gtacgcgtta ggacatctat aataatgctt ttcggtattc    264420
     ttcttgggca cagtatcatt acacacctca cagttgaacg taaccatcct gtaataacaa    264480
     atatttcttg actgagaccg tttgctgttg tatacagaat actcttagag ctcatcgcaa    264540
     gttaaaaatt ttcaattttt tttcactttt tcccgtcaag gcaaaaagca accaaaagag    264600
     aatgaacctt tatttttgat ttatttatta tgagatgctg ctagtccact catctgcatc    264660
     aatgtagtag tcacaaagct aatatttaga cgttactttg atatctctgt ccatgagagc    264720
     acttatttta ggaagttaaa tgagacagtc aatagttcac aatatcccgt cagcaatgga    264780
     gggaaaaggc attccttttc cataggattt taatcgtttt caagcatcat acgccctcga    264840
     ggaactcttg ttttcgcttt actatgcaac cattgatgta tttctgtata aatgtgcgtc    264900
     acgtggcctt gtgtctctta tttccacttg ttttttcaca atgcggaaaa cctcgattaa    264960
     agtagaaaaa aaggatataa taggagtata ccatattgga tagttcaatc tataaacaaa    265020
     caatcgcata accgcacgta tatacacgca cacacctatc aatcacaatg gctttggaac    265080
     ctattgatta tactactcac tcgagagaga tcgacgcaga gtacctgaag attgtcagag    265140
     gctccgatcc tgacaccacc tggttgatta tttcacccaa tgcgaaaaaa gaatacgaac    265200
     ctgagtctac cggttcctcc tttcacgatt tcttgcaatt gtttgatgaa accaaggtcc    265260
     agtacggact ggcacgtgtg tccccaccag ggtcagacgt tgagaagatt attatcattg    265320
     gttggtgtcc tgattctgcg ccattgaaga caagggcctc tttcgccgcc aattttgctg    265380
     cagttgctaa taatctgttc aagggttacc acgttcaagt taccgccaga gacgaggacg    265440
     atcttgacga aaatgaactg ttgatgaaaa tcagtaacgc ggccggtgcc cgttattcta    265500
     ttcagacttc ctccaagcaa caggggaagg cttccactcc tcccgtgaag aaatccttca    265560
     caccttccaa gagccctgct ccagtttcta agaaggaacc agtcaagact ccttccccag    265620
     cacctgctgc taagatttct tcccgtgtta acgacaacaa tgacgacgac gattggaatg    265680
     agcctgaatt aaaggaacgc gacttcgatc aggctcccct gaaaccaaat caatcatctt    265740
     acaaaccaat tggcaaaatc gacttgcaaa aagtgattgc tgaagaaaag gctaaggagg    265800
     acccacgtct tgttcaaaag ccaaccgctg ctggttccaa gattgatcct agttctgata    265860
     tcgctaattt aaagaacgaa tcaaaattaa agagggactc cgagtttaac tcctttttgg    265920
     gcaccactaa acccccctcc atgacggaat cttcattaaa gaatgatgat gataaagtca    265980
     ttaagggttt tagaaacgag aaatcacctg ctcaattatg ggccgaaaga aaggcaaagc    266040
     aaaacagcgg caacgccgaa actaaggctg aggcaccaaa acctgaagtt ccagaagatg    266100
     agcctgaagg tgaacctgac gtcaaagatt tgaaatcaaa atttgaagga ttggccgctt    266160
     cagaaaaaga ggaggaagaa atggaaaaca aatttgctcc tcctccaaag aaatcagaac    266220
     caactattat ctcaccaaaa cccttctcca agccacaaga acctgtgaaa gctgaagaag    266280
     ccgagcagcc taagactgat tacaagaaga tcggcaaccc attacccggt atgcacattg    266340
     aagcggataa tgaggaagaa ccagaagaga atgatgatga ctgggatgat gatgaagacg    266400
     aggctgctca acctcctttg ccttcgagga atgttgcgtc aggagcacca gtgcaaaaag    266460
     aagagcctga acaagaagag atcgccccaa gcttaccttc tagaaactcg atcccagctc    266520
     caaaacaaga agaagcacct gaacaagcac ctgaagaaga aattgaagaa gaagctgagg    266580
     aagccgctcc acagctgcca tcaagaagct ctgcagctcc tcctccgcct ccaagacgag    266640
     caactccaga gaaaaagcca aaggaaaatc cttgggccac agcagaatat gattacgatg    266700
     ctgcagaaga taacgaactg acctttgtgg aaaatgacaa gattatcaat attgaatttg    266760
     tcgacgatga ctggtggcta ggggaactag agaaagacgg ctcaaaaggt ctcttcccca    266820
     gcaattatgt gtctttgggc aactagaatc acacgtcagc gtcatgctat tatattattc    266880
     ttacgtaaaa aaatacttac agagacgtta aagcttttgt atagatactt tcacgagcct    266940
     tccctttcag taaaatgaac aaattatttt gccttgtcct tctttgtttc aagcgtttat    267000
     atgactcctc tacagtatta tttttcaaca gacggtgtgc ccgtacggcg ttgtcaaaac    267060
     ctcgaacata aaacaacact gaaacaaact tattgcactc ctgcatcgca tacagatctg    267120
     atacttacta caaccataat gctgttttag aatcgcatca ggtgtttacc agaagtgtat    267180
     ggtacatggt gctttcctta tgctcactat ttcggattta cttctagtct atgtatagat    267240
     ttgttagaga ccagttttaa gctacaatgg aacgttaaga ttaagaaatg catgaagagt    267300
     ctcccagtag atatataaag ctgaattaaa ttcagtacaa tggaagtttc cacgtctttc    267360
     tgtattttca tacctttaat tataggaaaa gcacactaca aaaatacgct atcatctacc    267420
     gaatataact gcaatgaact catttgcgtc attaggtctg atatattcag tagtaaacct    267480
     tttaactaga gtagaggctc aaattgtgtt ctaccagaat agtagtactt cactgcctgt    267540
     ccctacttta gtatccacct caatagcaga ttttcacgag tcctcatcaa ctggcgaagt    267600
     gcagtattca tcctcttatt cgtatgtgca gccctcaata gactccttca cttcatctag    267660
     cttcttaaca agttttgaag ctcctaccga aacttcttcc agctatgcag tttcttcctc    267720
     attgataact tctgatactt tttcttcata ctctgatatc ttcgatgaag aaacaagttc    267780
     attaatatca acctcagctg cctcatcgga gaaagcctcg tccacccttt cttcaactgc    267840
     acaacctcat aggacatctc actcttcctc ttcattcgag ctaccagtca ctgctccatc    267900
     atcctctagt ttaccgtcct caacttcatt gacatttacg tcagttaatc catctcaaag    267960
     ttggacttca tttaactcag aaaaatctag cgctctttcc tcaaccatag attttacttc    268020
     ttctgagatt tcaggttcaa catctccaaa gagcctggaa agtttcgata ccaccggtac    268080
     tataacttca tcttattctc cttctccttc ttcaaaaaat tctaaccaga cctcactact    268140
     cagcccattg gagcctctgt ccagttcttc aggagattta atattgagtt caactattca    268200
     agctactacc aatgaccaaa cttcaaaaac tattccaact cttgttgacg ccacatcgtc    268260
     attaccacca acattgaggt catccagtat ggcaccaaca agtggttctg attcaatctc    268320
     acacaacttt acgagccccc cctctaaaac aagtggtaac tacgatgttt tgacttcaaa    268380
     ctcaatagat ccttctctat ttacaactac gagtgaatat tcatctacac aattgtcgag    268440
     tttaaatcgg gcctcaaaaa gtgaaacagt taatttcact gcttctattg cttccacacc    268500
     atttggtaca gattcggcta cttctctaat agaccccatt agttcagtgg gttctacagc    268560
     atctagcttt gtgggaattt caaccgccaa ttttagtaca caagggaact cgaactatgt    268620
     tcctgaatca actgcaagtg gaagttcaca ataccaggac tggtcaagct cttctcttcc    268680
     gctgtcacaa accacttggg ttgtcatcaa cacaactaat acacaagggt ctgtaacgtc    268740
     aaccacatcc ccggcttatg tttctacggc caccaaaacg gttgacgggg tgatcaccga    268800
     atatgttaca tggtgtcctc taacacaaac caaatcacaa gcaattgggg tcagttcgtc    268860
     catttctagc gttccacaag cctcctcatt tagcggtagt tctattttga gctccaattc    268920
     cagcactctt gctgcctcga acaacgttcc tgaatcaact gcaagcggaa gttcacaata    268980
     ccaggactgg tcaagctctt ctcttccgct gtcacaaacc acttgggttg tcatcaacac    269040
     aactaataca caagggtctg taacgtcaac cacatccccg gcttatgttt ctacggccac    269100
     caaaacggtt gacggggtga tcaccgaata tgttacatgg tgtcctctaa cacaaaccaa    269160
     atcacaagca attgggatca gttcatccac gattagcgcc acacaaacct ctaaaccatc    269220
     ttcaatatta acattgggga tatcgacctt acaattgtct gatgccacat ttaaggggac    269280
     tgaaactata aacacccatc tcatgaccga aagtacttca atcacagagc ccacctattt    269340
     tagtggcaca tcggatagtt tttatttgtg caccagtgaa gttaatcttg cgtcttcctt    269400
     atcttcttat ccaaattttt catcttcaga aggctctacg gcgaccatta ctaactctac    269460
     cgttacattt ggatcgacca gcaagtatcc atctactagt gtatctaacc caacagaagc    269520
     cagccaacat gtgagctcta gtgtgaactc actcactgat tttacttcaa attcaaccga    269580
     aaccatcgca gttatatcta atattcacaa aacttcgtca aataaagact attcattgac    269640
     gactacgcaa ttaaagacca gcggaatgca aacgcttgtg ctttctactg tcacaacaac    269700
     ggtgaacggt gctgctacgg aatacacaac gtggtgcccg gcatcaagta ttgcttatac    269760
     gacatccata tcatataaaa cattagtttt gaccactgaa gtctgctctc attctgagtg    269820
     tactccaacg gttattacca gtgttactgc aacaagctct acaatccccc ttttatcaac    269880
     ctctagctct acggtattat cttctacagt atccgaaggt gcaaaaaatc ccgctgcttc    269940
     tgaagtaact attaataccc aagtttctgc tacttccgaa gctactagta ctagcactca    270000
     agtgtctgct acttctgcga cggccactgc tagcgagagt tcaaccacat cccaggtttc    270060
     tactgcttcc gaaactatta gcactctcgg tactcaaaac tttaccacta ctggaagctt    270120
     acttttcccg gctttgtcta ctgaaatgat aaatactact gtggtttccc gaaaaaccct    270180
     aattattagt acagaggtat gttcccattc caaatgtgtc ccaacagtca ttaccgaggt    270240
     tgttacttcg aaaggcacgc cttctaatgg acattcttct caaactctac aaacggaggc    270300
     agtagaggtg acattgtcat cccatcaaac cgtaactatg agtaccgaag tatgttctaa    270360
     ttcgatttgc acaccgactg ttattacatc tgtgcaaatg agaagtactc cttttccata    270420
     cttaacttct tcaacgtcaa gttcctcttt agcctccacc aaaaaaagtt ccttagaagc    270480
     ctcctcagaa atgtccacct tttctgtcag tacgcaaagt ttgcctttgg cattcacaag    270540
     ttcagaaaaa cgctccacca catctgtctc tcaatggtca aataccgttt taactaatac    270600
     aataatgtcc tcttcttcta atgtcatatc aacaaatgaa aagcccagta gtactacctc    270660
     tccatacaac ttctcttcgg ggtactcttt accttcttct tctacacctt cccaatattc    270720
     actatctaca gctactacaa caatcaacgg aatcaaaact gtgtacacaa cttggtgtcc    270780
     attggcagaa aaatctactg tagctgcttc ttctcaatct tcccgcagtg ttgacaggtt    270840
     tgtttcgtcg tcaaaaccat cctcatcttt atctcagacc tctattcaat atacattatc    270900
     tactgctacc accaccataa gtggtttgaa gactgtatac acgacttggt gtccattaac    270960
     aagtaaatcg actttaggtg ctactactca aacttcctcg acagccaaag ttagaattac    271020
     ttccgcttca tctgcaacat ctacttctat ttctttgagc acttcaacag aatcagaatc    271080
     ttcatctgga tatttgtcga aaggagtatg ctcaggtact gaatgtacgc aagatgtgcc    271140
     aacacaatca tcctcacctg cttcaacgtt agcatattcc ccctctgttt ctacatcatc    271200
     atcatcatca ttctcaacaa caactgcatc aacactaacg tcaacacaca cctctgtccc    271260
     gttattacca tcatctagct ctatatcagc atcttcgcca tcatcaactt cgttgttatc    271320
     cacttcttta ccatctcccg cttttacgtc atcaacactt ccaacagcaa cagcagtatc    271380
     ttcctccact ttcatagcgt cttctctacc attgtcctct aaatcatcat tgtcgttatc    271440
     gccagtctcg tcgtctattt tgatgtctca gttttcatca tcatcatcat catcatcatc    271500
     attggcatcg ttgccatctc tttctatatc accaactgtt gacactgttt ctgttctaca    271560
     accaactact tccatcgcaa cactaacttg cacagactca caatgccaac aggaggtatc    271620
     cactatctgt aatggatcca actgtgacga tgtgacttca actgccacta ctcctccatc    271680
     tacggttact gatactatga catgtactgg atctgagtgc cagaaaacca catctagcag    271740
     ctgtgatggt tactcgtgta aagtatccga aacgtataaa tcaagcgcta caatatctgc    271800
     atgtagtgga gaaggatgcc aagcttccgc tacaagtgag ctaaattctc aatacgtcac    271860
     gatgacgtct gtcattaccc caagtgccat aacaacaaca tcagtggaag tgcattcaac    271920
     tgaatccact atatcaatta ctacagtgaa gccagttaca tatacatcca gtgatactaa    271980
     tggagaactg ataaccataa caagttccag ccaaactgta attccatcag taacgacgat    272040
     aataacgaga acaaaagtgg ccataacttc agcaccaaag ccaacaacta cgacctatgt    272100
     cgagcaacga ctttcctcca gtgggattgc tacttctttt gttgctgctg catcctcaac    272160
     ttggattact acacccattg tcagtacgta tgctggttcg gcgtcaaaat ttctctgtag    272220
     taagttcttt atgataatgg taatggtgat caacttcatt taatttcccg tatatattat    272280
     atgtacgtat atatgctata aacagacact ctttttactt acctttaata atgcttgatg    272340
     agaaatcagt cattgttact tcttccccaa ggttgtcatc ataatcatac cattcattat    272400
     cctctagttg gcatgacatt actttccccg aacttagaga aacttcaaac gttatggtgt    272460
     cgggataaaa tttgattaat tcacaacctc tgcaatcaag gcttaaagga atgaaagaat    272520
     cttctttgac cttcgataaa ccatgcttct tccgcacatc ttttatcttg gcccatttgt    272580
     cgtcactctg atcagttaaa tattcatcct caaaagcgca caggttaact gacaattctt    272640
     ttgaacaaaa tttacacttc atcaagaaag atgcggtacc ttttgatgcc ggcatagcat    272700
     attcttcaaa tgtattgatg atgactttag aatcgtgtaa ttctctacaa ctggtacatt    272760
     gtagatcgaa ggcaaattct gcccttgatt cgtttgtatt ctcaattgaa accttggtca    272820
     cgttttctga taatgttgct ttcagaacca aaaataacgg cattatcgta cacaacctgg    272880
     ttttctttat tggttaagtt gtctttattc aaaatttttc attacttctt ataaacagct    272940
     tcttgacgct tgtaatttca taagtttttg atacaagcaa tggaaacaaa attaagaaaa    273000
     tgtaggcaac gaagaactaa atttgaaaaa aaaaaaaaaa aaaatttact gccaagatca    273060
     tctaaattat cttatagtag caaagcttga gcataaaagg atcaatcttt tagtttttta    273120
     tggcaaagta catttgcagt aagtaattag tgatgagata aacaaagaat aataatccaa    273180
     ttcgaaatca aaaattcaaa caacaaaaaa cataatttca catatatatc taattcattc    273240
     acgaaaaaca cgtcagttcc ttctgtctgt tgtaaatagg atgcatccgc agtgaatcat    273300
     ggaaatattt caaaactttc agcccaatca ttttatttgg tcaatgaagc cataaacgct    273360
     ccgtaattct aagattaaaa aaaattcata aaaataagga ccaatataaa tatatatatt    273420
     taatgtgcta gtgacaatcc tagtgataaa attgcaaatt atactacaat tggtcatggt    273480
     gaagcctaaa cacaccatta cgtcttcaca gtgttattca ttttattttc aaaggtatgc    273540
     tactactaat gcaccagtgt ataccatgat acggtgaaaa gggcatgtaa tattgcgtta    273600
     atttgtcgat aacctttctt tacgtttaaa tttttttttt ataactggcg acactaaact    273660
     tctcgataaa atacaacata aaaagcagta cctagctaag cgaacaacag ataataaata    273720
     gctaaacatc taggttaata gccaattagc aatacattta aggattgata gtgtggtatt    273780
     tacaaggtaa tagcccgcta ggctataagg aaactactct aaattcacct tccatatatg    273840
     tgactgccaa gaaaatatta ctagttatca agcttttttt gtgtgcattc aacttcaacg    273900
     aatccttcgt catcaatgaa acaaaagaac aagccagaac tgaaaaaaaa aaatcaaaac    273960
     cactaagaat gtcacatcct tccaaaactc ctgctggctc ttcaactctt caaagaatat    274020
     caagataaat atcattatct ccagtgtggc cgacccatgc atgagtgcga ggagcattaa    274080
     gttggatcct gggaaaacat gtcaaggaca ttcaataaag tacttttcat actacaacag    274140
     acgctagaag aactagaatg taaccgtgaa ctgcctctca aacacataat tatgatagcg    274200
     ccgtcttcgg catccttttt cggaaatata ctttcctttt tccctctttc agctatattg    274260
     ttcaaggagt aacataagac ataataaccc cagttttttt agagaaagtt cttcttcttt    274320
     aattatagta tgtttgaaac gtacaagaat tcattgagtg ccctaaggat tactgcaaac    274380
     aaggttcaac agtgttggta cacatgactc agcaagaata ccgttccccc tcacaacgct    274440
     tatccaaggg gaggagcatg tcgctaccca aaatatttgc tcgtaatttg agatctctgc    274500
     aaaacaatgc acctcctggc aaaaacatca atgtcaattg tttgaacgtc aattcttgtt    274560
     cgttgtccgc aagcccaagc tcacaaatta atatggcttg taatggaaac aagcaagatc    274620
     ttcccatacc gtttcccctg catgtagaat gcaacgatag ctggtcaagc tccaaactta    274680
     acaagttcaa atcaatgttt aatcataaca gatcaaagag cagtggtact acagatgcgt    274740
     caacttcaga aaaaggtacg cataagcgtg aaccccggtc gacgatacat acagagctgt    274800
     tacaaagttc cattatcggt gagccaaatg tccatagtac tacaagtagc acacttatac    274860
     ccaatgaggc gatatgctcc acacctaatg agatctcagg tagctcttct ccggacgcgg    274920
     agttatttac ctttgacatg cccacagacc cgtcatcctt ccacactcct agctccccaa    274980
     gttatatagc aaaggacagt agaaacctga gtaatggatc tttgaatgat attaacgaaa    275040
     atgaagagct ccaaaatttc catagaaaaa tcagcgaaaa tggcagtgcc tcccccctgg    275100
     ctaacttgtc attatccaat tcaccaattg attccccaag gaaaaatagc gaaaccagaa    275160
     aggatcaaat acctatgaac ataacaccac gtttaaggag ggccgcttcc gaaccgttca    275220
     atacggcaaa ggatgggtta atgcgggaag attacattgc cttgaaacaa cctccaagct    275280
     tgggagatat tgtagaaccg aggagatctc gtcgtttaag aaccaagtca ttcggtaaca    275340
     agttccaaga cattactgtc gaacctcaat ccttcgaaaa aattagacta cttggccaag    275400
     gtgacgtagg taaagtgtat ttagtgaggg aacgcgatac caaccagata ttcgccctga    275460
     aagttttgaa taaacatgag atgatcaaga ggaagaaaat taaacgagta ctcactgaac    275520
     aggaaattct cgcgacaagt gatcatccat ttattgtgac actgtatcat tcctttcaaa    275580
     ccaaagacta tttgtatctc tgtatggaat actgcatggg aggggaattc tttagagcct    275640
     tacaaacaag aaaaagtaaa tgcattgcag aagaagatgc gaagttttac gccagtgaag    275700
     tagtagcagc tttggaatat ttacacctac tgggcttcat atacagagat ttgaaacccg    275760
     aaaacatatt actgcatcaa tctggtcatg tcatgctttc tgactttgat ttatccatcc    275820
     aagcaacggg atcaaaaaaa cccaccatga aagactctac gtatttagat acaaaaattt    275880
     gttcagatgg attcagaact aattcctttg ttggtactga agagtattta gctccagaag    275940
     taatcagagg gaatggccac actgcagcag tagactggtg gactttagga atattgattt    276000
     acgagatgct atttggctgt actccattta aaggagataa ttcaaatgaa acattctcta    276060
     acattttaac caaggacgtc aaatttccac atgataagga agtttcgaag aattgtaaag    276120
     acctgataaa gaaactacta aacaaaaacg aggcaaaaag gcttggttcc aaatcaggag    276180
     ctgcagacat aaagagacat cccttcttca aaaaagttca gtggtcgttc ttaagaaacc    276240
     aagacccccc tctaatacct gcattaaatg ataacggctg cgaacttcct tttatattgt    276300
     cttgcaataa acacccgaaa aggaactcag tgagtgaaca ggaaaccaaa atgttctgtg    276360
     agaaagttgc aaacgatgat gaaattgatg aggctgatcc attccatgat tttaattcta    276420
     tgagtttaac gaagaaagat cacaatatct taacctactc tgaaaattat acctacggaa    276480
     aaattctata caaagcaact tgtacaaggc caaggcataa cagctcacat agaagtttct    276540
     ttaaagacat catacctgaa ctataacatg tttacagaaa gataaaccca tggccaaatt    276600
     tctgtattgt ttctctcaat ttatcttatg ataaaaatgt aaaaaattat ttaaaagtaa    276660
     acaaataaac aaaggaacaa ttcaaaaacg agaaagtgaa tgaaaaatat aatatcattt    276720
     attgtctgat aatgctgcat ttagaacata cgtaccatcc gcatcagtgg atatccaatg    276780
     atagtaattt cgcgagttta tccgttgctg ttatattatc actttttaat attcttttca    276840
     aagagctgaa taatttcaac gcgtcttcgt taatggattc cttccgcaat tcttctgaaa    276900
     tactgaatgc ccgatttata atatctttgt ccaggcgtgc caatttcgcc acattcatcc    276960
     cataactatt ataagtcaat ccctttttta acttatatag aaaaattaca ctcatccagt    277020
     cctcgccagt tttttgttct tccacgtaat ccatatgata attccttatt aacggagatt    277080
     tgatttctcc cagcatggga aaatgggtag taaataatat caaggggcag tcacttaact    277140
     cagaaaaata ctttattaaa gcataagaaa ttgctatacc atcgtgcgtg ccagtacctc    277200
     ttcccacttc gtctaataat agtaaagacc gtttattgca atttttcaag atgtgtagga    277260
     tatcaagcat ttccacttta aaagtagaat caccgtttat aatatcatcg tgcgcaccga    277320
     ttcgagtgag tacgttttca aatatgctta atctgatctc ttctgcgggg acaaatgagc    277380
     cgatctgtgc cattatagta agcagtgcca cttgtctaat ataagatgat ttcccaccca    277440
     tattcggccc cgttataata ttgattttac cgttttctgg ggacatcatg atatcatttg    277500
     gtacataatg aacatccagc gactcgataa ttggatttct tgcatttttt gcgattatgg    277560
     cttgttgacc attcacaaaa gttggtctaa cataatttac gttgcatgat gtggctgcta    277620
     acgacaaaat acagtcatac tgcgccaaat tgagtgtaat tttacggagc tctgtatatt    277680
     ctgccgtaat tttgttcaag aattctttat actgtagttc agattcccga attaataagt    277740
     ccttgtaata ttctagcttt tgagtcagtt tctgggttct gggagtggta aatctactga    277800
     ccatcttcgt attgttaact tttatccaat catctggcaa gtccttaatt tgcgagtttt    277860
     tcacttcgat taagtaatca acttcatctc taaaatttag atatggacgt ttgagatatt    277920
     ttcgtatttc tgccaattct tcctttaact gtgaccgtac tgattcgctt tccctttgaa    277980
     tttttattat accctctgaa caatcatagt tatttaaatt aaaaaaatcc attacttgct    278040
     tatctgaatt tttttccatt accgcagaaa cgttgatcat ggtcaaaaaa tgaggcaact    278100
     gagtggtaga aagtagttca ttcaattcac taaatagtct aaaaagtaaa ggagattgtt    278160
     tgcctatcct tccatctgat gacttgaaat gttctgacag gtaagattga tgcatcttga    278220
     agtgatcaac gaaagaagtt atttgcttta aatagaaata gacttctttt ctagaagttg    278280
     taccatacat tatgcgattt aaagttctta ataagtcagg ggtatgattc aacatttgat    278340
     tcaacgattc aaaaaatata ctgttgttga tttcggatgt aatgcactca atggcatcaa    278400
     gccgctcttc aatttggtgt acatcaacca aaggtttgag aatccattct ctcaacattc    278460
     ttaatccaaa cgatgtcctt gtatggtcca ataaccaaaa caaagaacct ttaccaccat    278520
     catgggtaaa aatgtccaaa ctttgcaggg agttaggatc aagtaacata tgtatttttg    278580
     atgcgaaggg cgaatagata gaaggaatca acatcacctg ctcattattg tactcaacca    278640
     tatgcgaata taacttagaa actaagcgta tgagagacgg cgagagttga attttctcat    278700
     tcattacttt tattgcctga actacatgat cttccaaatc atactcctgc ttgtgtatta    278760
     aaggacatga aatatctttg aaaaatttcg ctacatgtaa tggaagatca tctgtattta    278820
     ccagtacttc tatgggctgt aaatatttga ttcgtatctg tagtttctca tcagcaagat    278880
     taggctcttc aaattcatca tacacgactt ccccgttatt taaattgaca gaaattaagg    278940
     aatatttagc cacctttccc tgatgtacgt cacgggacaa agcccatata ctgtttgtat    279000
     caccgagaat acgtttcccc ctaaggacaa aggtggaatt aacaccaaat gtagctttgg    279060
     taaagacatt tgaaatcttt ctttcaaaaa cgcttgattt gctggcacct ggatcatgct    279120
     tcttaatagc gcttgtttct gcttgctcta ccacggcaac ctttaaatta tgatgcacaa    279180
     gtctctctag gtgaacgttt aatctgacat ccgggaaaga acagtacgca aactgcctat    279240
     gattgcaatc ttgaggatta gactcatcga tagtcaattt tccaggcaca agtttgatgt    279300
     gaagtattct gctaaccgtt actgcatcct ctgcaaaaca tttgtacttg tagcctactc    279360
     taataacaag cactttatct ctatgatgca ttttcaggtc cttcacctgt ttgtccaagg    279420
     gagtaagttt cgctgtaggg gactttctgg cttttttttt tacgaaatct tcctcaccct    279480
     cttcctcatc atcttcagcc tcaacatttt catcacttcg tcttttcata atcctatcca    279540
     atttcttagc aaagtcaata tcattaaatg ttgtcgaagt accactagtc ttttctgaat    279600
     ttttcgaatt cttggaagaa acactgcctt tgagtggaaa gctatcatta gttactgttg    279660
     tgcttgcaac agaagataaa ttgtcctctt catcagtgtc aaggcagatg gattcgctac    279720
     cagcgccatt tccaaccgca acttcttgtt cttgcttatg cgtcagctct gattttaccg    279780
     ccttcttgaa aaacctgctt attgtgggtt gtcccgccat tattgttaat agattcaaca    279840
     aaataaatct atttgcactg cttttggctc tcaaaagtac cagtttaggt tcattaccta    279900
     tcaccattgt tccagcttat ttatcattga aaattcacgt gatcgcaata ttccgtcagg    279960
     agtgataaat acacgaaaat ttttcttttt tttcggtggc aaccaaagtc aaaccatcga    280020
     attcgaataa gataaacagg ggcaaaggtg agtcggggaa acactattgg taaaagataa    280080
     gcaattgaga aacgtcactc agggacaatt gattacatgc tatcggccac ataccgtgat    280140
     ttgaacacag catctaattt agaaacatca aaggaaaaac aggccgctca aatcgtcatt    280200
     gcacaaatta gtttattatt cacgactctt aacaacgaca attttgaatc cgtggaaaga    280260
     gaaattagac atattttaga caggtcgtcc gtagatattt acataaaagt ttgggaacga    280320
     ttattaacct taagttctcg ggatatttta caagcgggaa aatttttact tcaagaaaat    280380
     ctactacaca gactactatt agaatttgcg aaggatttac cgaagaaaag cacagacctt    280440
     attgagcttt tgaaagaacg aaccttcaat aaccaggagt ttcaaaaaca aacaggaatt    280500
     acattatcac ttttcattga tctatttgat aaatctgcaa acaaggacat tatagagtca    280560
     cttgaccgct cctctcagat taacgatttc aagacaatta agatgaatca tacaaattat    280620
     ttaaggaatt tttttcttca aaccacacca gaaacactag agtccaatct acgcgactta    280680
     ttgcattcct tggaaggtga aagtctaaat gacttattag ctcttttact gtccgaaata    280740
     ctttcacctg ggtctcagaa tttacaaaat gatcccacac ggagttggtt gacacctccg    280800
     atggttttag acgcaacgaa ccgtgggaac gttatagcaa gatctataag ttctctgcaa    280860
     gccaaccaga taaattggaa tcgtgtgttt aatttaatgt caacaaagta tttcttgagc    280920
     gcaccattga tgcctactac agcatctttg agttgcttat ttgcagcatt gcacgatggt    280980
     ccagttattg atgaattttt cagttgcgac tggaaagtta ttttcaaact agatttggcc    281040
     attcaacttc ataagtggtc ggtacagaat ggttgctttg acttattaaa tgcagaaggt    281100
     accaggaaag tttctgaaac catcccaaac acaaagcaat ctttactcta cttattatcc    281160
     attgcatcat tgaatttaga attgttccta caaagggagg aattgtctga tggtcctatg    281220
     ctagcttatt ttcaagagtg cttctttgaa gatttcaact acgcccctga atatcttatt    281280
     ttagcattag tcaaagaaat gaagcggttc gttttattga tagaaaacag gacagtcata    281340
     gacgaaatac ttattacctt attgattcaa gtgcataata aatcaccgtc atcgttcaag    281400
     gacgttattt ctacaataac cgatgattct aaaatcgtag atgcagcaaa aatcataatc    281460
     aactcggatg acgcacctat tgccaacttt ttaaaatcgt tgttagatac gggaagatta    281520
     gatacggtca ttaataaact tcctttcaat gaagctttta aaattttgcc atgcgcaaga    281580
     caaattggtt gggaggggtt cgatactttc ttaaaaacaa aagtttctcc atctaatgtc    281640
     gatgtagtgc tggaatcact agaggttcaa acgaaaatga ctgatacaaa cactccattt    281700
     aggtcattaa agacatttga cttattcgct tttcattcat taattgaagt actgaacaaa    281760
     tgcccactag atgttctcca attacaaagg tttgaatcct tggaattttc cttattaatt    281820
     gcatttccta gattgatcaa ttttggtttt ggacacgatg aagctatttt agccaatggt    281880
     gacatcgcag ggattaataa tgatattgaa aaggagatgc agaactattt acagaaaatg    281940
     tatagtggtg agttagccat taaagatgta atcgaacttc tgagaaggtt aagagatagc    282000
     gacttgccaa gggaccagga agtcttcaca tgtattaccc atgccgttat agcagaatcg    282060
     acattcttcc aagattatcc attggatgca ttggctacta catctgttct ttttggatcc    282120
     atgattctct ttcaactgtt acgtggattc gtattagacg tcgcatttag gataatcatg    282180
     aggtttgcca aggagcctcc agagtccaag atgtttaagt ttgctgtaca agctatttat    282240
     gcatttagga tacgtttggc cgaatatcca cagtattgta aggacctctt gagagatgtt    282300
     ccggctttga agtctcaggc tcaagtttac caatctatcg tcgaagctgc taccctagca    282360
     aatgctccaa aggaaaggtc aagacccgtc caggaaatga tcccattaaa attttttgct    282420
     gtagatgaag tttcatgtca gatcaatcaa gaaggtgctc ctaaagatgt cgtagaaaaa    282480
     gttctttttg ttctcaacaa cgttactctg gctaacttga ataataaggt tgatgaattg    282540
     aaaaaaagtt tgacaccaaa ttatttttct tggttttcca catatttagt tacgcaaagg    282600
     gctaaaacag aacctaacta tcatgatctt tatagcaagg ttatagttgc tatggggtca    282660
     gggttgctac atcagttcat ggtcaacgtt actttgagac aattatttgt cctactatct    282720
     acaaaagacg agcaagccat cgataaaaag cacctaaaga atttggcttc atggttagga    282780
     tgtatcacat tagctttgaa taaaccaatt aaacacaaga atatcgcatt cagggaaatg    282840
     ttaatcgaag cttataagga aaatagactt gaaatagttg tgccttttgt aacaaagatt    282900
     ttacaaaggg cttctgaatc aaaaattttc aagcctccaa atccctggac tgttggcata    282960
     ttaaagctgt tgattgagtt gaacgaaaaa gcaaactgga aattaagttt gactttcgaa    283020
     gttgaggttt tattaaaatc ttttaatttg accaccaaat ctctcaagcc ctcgaatttc    283080
     atcaatactc cggaagttat agaaacttta tccggtgctt tgggatcaat cactctggag    283140
     caacaacaaa cagagcaaca aaggcaaatt atactaatgc aacaacacca gcaacagatg    283200
     ctaatatatc aacagagaca acaacaacaa caacaaaggc aacaacaaca acaacatcat    283260
     attagtgcaa atacaatcgc agaccaacaa gcggcatttg gcggcgaggg ttcaatttca    283320
     cacgacaatc cttttaacaa cttacttggt tctactattt ttgtaaccca ccctgacttg    283380
     aagagggtat ttcaaatggc tttagccaag tcagttcgcg aaattttgtt ggaagtagtc    283440
     gaaaagtcat caggaattgc tgttgttacg acgacaaaaa taatacttaa agactttgcc    283500
     actgaagttg atgagtctaa gttgaagacg gctgcaatca ttatggtaag gcatttggca    283560
     caaagtttag ctcgagctac ttcaattgaa ccattgaaag aaggcatacg ttctactatg    283620
     caatcactag caccgaattt aatgtctctt tcttcttcac ctgcagagga gcttgacacg    283680
     gcaataaatg aaaatattgg cattgctcta gttttgattg agaaagcatc tatggacaag    283740
     tctactcaag atttagcaga ccaattgatg caagcgattg ctattcgtcg ttatcacaag    283800
     gaaagaaggg cagaccaacc atttattacg caaaatacca atccatattc actgtcttta    283860
     ccagaacctc ttggtttgaa aaacactggt gttactcctc aacaattcag ggtatacgaa    283920
     gaatttggta agaatattcc aaacttggat gttattccgt ttgcaggatt gcccgctcac    283980
     gctccaccga tgactcaaaa tgtgggttta actcagcctc agcaacaaca agcgcaaatg    284040
     cctacccaaa tcctaacctc cgaacaaata agagctcaac aacaacagca gcaattacag    284100
     aaaagccgtt tgaatcagcc atcccagtcg gctcaacctc caggagtgaa tgtcccaaat    284160
     cctcaaggtg ggattgctgc agttcaatca gatttggaac agaatcaacg tgttctcgtt    284220
     cacctcatgg acattttagt ttctcaaatt aaagaaaatg ctacgaagaa taacttagct    284280
     gaattaggcg atcaaaacca aattaaaacc atcatttttc aaattttgac attcattgca    284340
     aaaagcgcac aaaaggatca attagcttta aaggtatccc aagctgtcgt taatagcctt    284400
     tttgccacta gtgagagtcc tctctgcaga gaagttttgt ccctactttt ggaaaagtta    284460
     tgttctttat ccctcgttgc tagaaaagac gttgtctggt ggttagttta tgccttggac    284520
     agtaggaaat tcaatgttcc cgttatcaga tcccttctag aagttaattt aattgatgct    284580
     acagaattag ataacgtttt agttactgca atgaaaaata aaatggagaa ctcaactgaa    284640
     tttgctatga aattaattca gaatactgtc ttgtctgatg atccaatttt gatgagaatg    284700
     gacttcatta aaaccttaga acacttggcc tcttcggaag atgaaaatgt aaagaaattc    284760
     atcaaagagt tcgaagatac taagataatg ccagtgagga aaggtaccaa aaccacaaga    284820
     acagaaaagc tttacttagt atttacggaa tgggtaaaat tacttcaaag agttgagaat    284880
     aacgacgtaa tcacaactgt ttttatcaag caattagtcg aaaagggtgt tatcagcgat    284940
     actgataatt tacttacatt tgtcaaaagt tctcttgagc tatcagtttc ttcattcaaa    285000
     gaaagtgacc cgactgatga ggttttcatc gctattgatg ctctaggatc gctaattata    285060
     aaattgttga ttttacaggg tttcaaagat gatacaagaa gagattacat aaatgcaata    285120
     ttttctgtga tcgttttagt gtttgctaag gatcatagcc aagagggtac cacattcaat    285180
     gaacgaccat atttcagact attttctaac atcttatacg aatgggctac catcaggacg    285240
     cacaattttg ttagaatatc tgattccagc actaggcagg agctgatcga atttgattct    285300
     gtattttaca acactttctc aggatatttg cacgctctgc aaccatttgc cttccctgga    285360
     ttctcatttg catgggtgac actattatca cacagaatgt tattaccaat tatgctaaga    285420
     ttacccaata aaataggttg ggaaaagtta atgcttttga ttatcgattt gtttaaattt    285480
     ttggaccaat acacaagtaa acatgcagtc tctgacgctg tttcggttgt ttataaggga    285540
     acactgcgtg ttattttagg catttcgaat gatatgccat cctttttgat tgaaaatcac    285600
     tatgaattaa tgaacaatct acctccaaca tatttccaac taaagaatgt tattttatct    285660
     gctattccta agaatatgac cgttcccaac ccatatgacg tggatcttaa tatggaggat    285720
     attccagcat gtaaagaact acctgaagtc ttctttgatc ctgtaattga tttacactca    285780
     ttgaaaaagc cagttgacaa ctacctacgt attccctcaa attcattatt aagaacaata    285840
     ctaagcgcta tttacaagga tacctatgac ataaaaaagg gcgtaggcta cgacttttta    285900
     tctgttgata gtaaattaat tcgcgctatt gtattacatg tgggcattga agctggaata    285960
     gagtataaga gaacttcttc aaatgcggta tttaatacga agtcttctta ttatacttta    286020
     ttgttcaatc tgattcaaaa tggtagcatc gaaatgaaat atcaaattat tctgtctatt    286080
     gtggaacaat tgcggtatcc aaacatccac acctattggt tcagctttgt gttaatgaat    286140
     atgttcaaaa gtgacgaatg gaatgatcaa aaacttgaag tccaagaaat tattttaaga    286200
     aactttttaa aaagaattat tgttaacaaa ccacatacct ggggtgtttc agttttcttt    286260
     actcagttga taaacaataa cgatattaat cttttagacc tgccctttgt acaaagtgtt    286320
     cccgaaatta aactaatttt acaacaatta gtaaaatatt ccaaaaaata cacaaccagt    286380
     gaacaagatg accaatccgc caccatcaat agaaggcaaa cccctctaca atccaacgca    286440
     taaaaaaact gcatttattt atatacgaaa atcatgattt cagaaaaaaa aatataactt    286500
     gtataatact atatttcaga gaatactatt ttgaataaga atagaagcaa tttcgattaa    286560
     cttttcttac tgtatatggg tcgctttcac ttttgaacta ctgaaaatta gtgttacccg    286620
     tattattgtt ttggagaata ataataataa tgagcatcaa tttatatcaa acaagagctg    286680
     caattacctt atgtccatga cgcactgcga acaaagaata attgagtaat cgaacttgaa    286740
     gttctataga acagcttgta tatggtttca ttgttcaaaa gaggtaaggc tccaccgctc    286800
     acgaaagaag gccccacttc taaaaagcct cctaacacag cgtttagaca acaaaggctt    286860
     aaggcatggc aaccaatact gtctcctcaa agtgtgcttc cgttgttaat attcgttgca    286920
     tgtatattta ctcctattgg tattggactc attgtaagcg ctactaaggt acaagatcta    286980
     acaattgatt atagtcattg tgatacaaaa gcatctacaa ctgcttttga agatatacca    287040
     aagaagtaca ttaaatatca ctttaaaagt aaagttgaaa ataaaccaca atggaggcta    287100
     accgaaaatg aaaatggcga acaatcatgc gaactgcagt tcgaaatccc aaacgatatc    287160
     aagaaatcca tttttatata ttataaaata accaattttt atcaaaatca tcgcagatat    287220
     gtccaatcgt ttgacacaaa gcaaatatta ggggagccta tcaaaaaaga tgatctggat    287280
     acaagctgta gtccaataag aagtagggaa gacaaaataa tatatccctg tgggttgatc    287340
     gctaattcca tgtttaatga tacattttct caggtgttga gtggtataga tgacacagaa    287400
     gactataatt taactaacaa gcatatatca tggagtattg atcgtcacag atttaaaacc    287460
     accaagtata atgctagcga tattgttcca ccgccaaact ggatgaagaa gtatcccgat    287520
     gggtatacag atgaaaatct tcctgatatc catacttggg aagagttcca ggtatggatg    287580
     aggactgcag cctttcccaa gttttacaag ttgacgttga aaaatgaatc tgcttcttta    287640
     ccgaagggta aatatcaaat gaacattgag ttgaattatc cgatttcact ctttggtggc    287700
     acaaaatcat ttgtactgac tacaaatgga gctattggtg gtagaaatat gtcactaggc    287760
     gtactgtacc tcatcgttgc agggctttgc gccttatttg gcatcatttt tttggttaaa    287820
     ttaatcttcc aaccaagagc gatgggtgat cacacttatt tgaattttga tgatgaagaa    287880
     aacgaggatt atgaggatgt acacgcagag aatacaacat tgagggaaat tttatagagg    287940
     ccaaaaaaca aactttagtg cctgtaggta tttgtgttta taagtaaaca agttttgttg    288000
     acttcctgaa acgtaaacaa aagaaaaatt gaagtatgcc tttttacgct tggaaaatag    288060
     tgcgacaaag aactcccagg gtttgctatt cccatttaga tgatgaaatg atagaaaagt    288120
     ggaaaacgtt tatcatgaaa tcatctatac atatacgtaa aaatgtaaac tatgtaaaaa    288180
     tatgttccct ataaaagtga tgctcttccg gaacgttttc tttttcccac aaatctcgtt    288240
     gaaacctgaa ccaatctggt aattcagaat cacagggtat ccttattttg acgttatctt    288300
     ttccccttgc tttataatag ccataatctc cattttcttt tttattaaat gctaatctat    288360
     acctatggcc aaaaattcct aggtcagaag aggttttctt caaatcgtct cctagaactc    288420
     cacttacttg taatacttta ttatttttca ctttggtttc gatttgattt attaatgtca    288480
     aaagccgctg aggcacttct ggctctctgc aaaggtcatc ttcatttact ctaataagtt    288540
     tgccagaatt ggccttatac tctatcgaat gcgtcctatt attctcaagg ggcaattttt    288600
     ttgctttgtt gtccacaatt gtcttattat ccttctcctg ttctatctca atgttaatta    288660
     tttctagaaa tgtttccgca aaataatttc tattcttacc agaaaataat ctgtactcat    288720
     ttatgattga tgcaatattc catttctgaa tttttcgaag tataccaatg accaacgcgg    288780
     tcttatctac caataaaaca ttataattat ccacattcaa taatgttttg aaagttcttt    288840
     ttaaacacgt gctcttaatc agcattaagt catcattgtc agtcaagtgg taagccaatt    288900
     cctcctgaat tacaggatcc cctgtagtag aattttgtga cccatttgca gtggattttt    288960
     tcttttcttc ctgtaatgat agagtactgt tattattcga atataaattt gcgttagata    289020
     cagaagagct ttttaccgga actgccgcag ccgagaaatc agacatcctt aaaacaatcc    289080
     attttatgga tgatcttgtg aaaaaatctt tgaaaaactt ggatggttct tgacctccaa    289140
     taaatatagc tgtctttaaa ttgagagttt ccagaaagga taaatttaat gtctccactt    289200
     tagaacatct atatattcct tcttcagcaa tcccaaagtt agcaggtgga accagcatta    289260
     tgaattcagg ttatggatcg caccagtgct gtaagtgtct ctctttttat tctacgatct    289320
     ccatataaca accacatctc atttctttac cttactgtcc atttaatgct agaaaacttc    289380
     cgaatattgt attattatta cccggatatg tcaaggcggt atattaagat gttcctttca    289440
     aaagtttcat tataccgcat acggtaagga cagccataag tagttttact gataaaatat    289500
     ggggctaaag aactgtatat ttatggatag cactaaaagt aaagattttc cccgtgtcct    289560
     gacttggaga aacaaaattt cattgtcata aaaaactttt aaaatatgat attcaaagct    289620
     tgagcattgg gcttctggat gacagttcta atcaagttgg gtctaaggat attgcatgta    289680
     tacaaaggat tctttcggaa agtaatcctg aaatattttt ttttttcgtc tgaacatacg    289740
     aaagtaaata aaaaaagttc aatgcatgcc ttcctatgca agatttataa aaggtgaaca    289800
     ggtcaggagc agccacatct caataaaggc agttaaagac ggtgatgtag gtgcagaaag    289860
     agaaagtgaa caaaggatga tttgagatgt gtaatgattc gtttgagcag caacaactgc    289920
     taagatattc atactaatag gccacttcac acattatgcc ttggagaata tcctgcattg    289980
     ctccttttat agtatagtct attcagcact aacaagcaaa gcgaacataa tggtaaaact    290040
     aacttcaact gttgctggtg tcgcctgcat cgctggccct cccctccact acggccattt    290100
     tagcacaact tgaatgagtc aacttggttg agttgcatgt taacgtctct gatatcagag    290160
     ctcacttgct caataataca tgttacaaac tgcccactaa attgaacact ctaacattat    290220
     attgacctga attatttgaa acgaagtcaa cagaatgatc actgattttc caatgtactc    290280
     cgctatgttg aagctagcca tcttaagcga tcaatgacgg tgctcaatca ttcttcgaaa    290340
     tgggctaaaa atgacagttg aaatatattc tttacgttca ttttttttca tactgcaaac    290400
     ccattctaga accaatggta aaagtgacgg gagttgcttt cttttactat ttcaatgata    290460
     gctatagcct gcatacacac aaaagaatgt aagtgattgc gtgaaagctt aaagtcttaa    290520
     aactgtattt ttttcaactc ctcccatata ttaaactggt cctcacagtt cgcaggataa    290580
     ctaacaatta aaaaaattgt tcatatggtt gtatttcttt ccgtctcaca ttattaaaat    290640
     tcaacgaaga agtttctaca ataacagaca agggcctacg attactatgt actggaaggt    290700
     gagtcttgaa ttcatcctca gagattgttc taaagaccaa cagaaatcca tatagattac    290760
     cgtagttact ctgatggaat ttcagagtaa gacccttgtc aacttcatca ctttaagttg    290820
     agatgtagaa agacactttt gtaaggtctc caacaagtat atttgataaa tagactgttg    290880
     agctacaaaa actcaatgtg aagtaaaaga cctcataaat gatcgattat ctgtttggca    290940
     ggtactaata aaactgcatt ggtgtctttt ttcacttacg ttaaaaaaaa ctttttgcaa    291000
     tgatttaagc gtgcgtgaag ataacactac aatccatttt aaagcaacat ccacattgag    291060
     tgtatacacc acaaaggttt tttcagggcg tttttctcgc cactttatgt tgaccaaaat    291120
     tattaatgga acttacaacg tttccaaaag ttagttaaat acatacgtct atttactaag    291180
     caagaaatat atcatgacaa gcccaaatat tatattgtta tgtttacaaa aaaaaaatgg    291240
     ctatatacat caagtctgga ggctttttat aacaagcaag tggggtaact tagacataag    291300
     attgacttct ttgaattcaa caaaaataca tacttttgat gatttcaatg gtagaagcag    291360
     tagtaactat gccgatgaaa taaaatcctg atatcatcta tatagtagta ctcacgttac    291420
     tagtatatca tctataagat gtaggaaaat gtcataagaa atgagaaaca gtcattaaat    291480
     ttaatggaaa cgaaatgcaa ggattggtga tgagataaga taatgaaaca tagaaaacga    291540
     aaggagaaat aacagtagta ttattattat tattattatg tagaaatatt gactctctct    291600
     tgtagattca tatatcttca aggggaactt cttgtacatt ttgtatacct atattatagc    291660
     gtttaacaac aatggaatcc caacaattac caaaattttc acacattcct catataaaat    291720
     ctaagcaatg actagagaac tatcgctaaa ttatatagag caaggaaacc gaataattac    291780
     atgtgtcaga taagaaaaaa ataaagaaaa caacgcgtca tgaaaaagag ttactgaacc    291840
     ttcagatcct acttattgta atgcttcgcg acatccaatc catttaataa tcaatttaaa    291900
     actagagttg gtagagttcc ttgttgaacg tgataaccca aaagcataat acgagtaatg    291960
     tttcagtatt gctattatat gtttacacaa ggaaaacata taataacaaa cctctaatcc    292020
     ggtagtactt aagaaactat agtttctatg tacaaaaagg taactatgta attcttacat    292080
     ttacataaca tatagaaggg tccaataaac ttactaaact tactaccttg ttgtatatag    292140
     gctagatcgt aatccactac gtcaacataa aaaaaactta aggagtttga attttatgta    292200
     caaacagatt gttaaaatat aatataagat tatggaaacg aacttgctct aaaaaaaatt    292260
     taaagtttta taaaatcctc gcactatcgc tgttatacat gatgtcccca aagcgtgtac    292320
     aaataatttt gtagtattgt atcggtaata tcatacaaga agaaaatagt tgcaaatctc    292380
     taacccacta gtacttaaaa aaactgtagt ttcagtgcaa aaaagtttta acattacgta    292440
     tcttgtaccc tttttattgc atatagaaag gtcaaataat ccttcacatc atgaaatata    292500
     agctaaatcg catttctttt cgtccacatt tgcaaacaaa acttttcaat aataatttta    292560
     taaatagtat caatatatat atatatatat atatttattt gtttactttt tctatcagtg    292620
     ttttcaattt tttattaaac aatgtttgat tttttaaatc gcaatttaat acctaaatat    292680
     aaaaaatgtt attatattgc aaaaacccat caaccttgaa aaaaagtaga aacgttttat    292740
     ttaattctat caatacatca taaaatacga acgatccccg tccaagttat gagcttaatc    292800
     ttccataaaa atatttgaaa gcaatagatc atgtactaaa ctaaaatcag ggaaattaag    292860
     actccttttg aagtaatacc tattacttac taatacgttt gagaataagc gcaggtactc    292920
     ctggtttttg ttaaaactac aaatttatac ttagcattac gaagattctc gattccgaaa    292980
     aacaaaaatt ttatcgtcat atacaaatct agaaattacc agagctatcc atcttgttca    293040
     agaaggtagg cgaggacatt atctatcagt acaaacatct tagtagtgtc tgaggagagg    293100
     gttgattgtt tatgtatttt tgcgaaatat atatatatat atattctaca cagatatata    293160
     catatttgtt tttcgggctc attctttctt ctttgccaga ggctcaccgc tcaagaggtc    293220
     cgctaattct ggagcgattg ttattgtttt ttcttttctt cttctattcg aaacccagtt    293280
     tttgatttga atgcgagata aactggtatt cttcattaga ttctctaggc ccttggtatc    293340
     tagatatggg ttctcgatgt tctttgcaaa ccaactttct agtattcgga cattttcttt    293400
     tgtaaaccgg tgtcctctgt aaggtttagt acttttgttt atcatatctt gagttaccac    293460
     attaaatacc aacccatccg ccgatttatt tttctgtgta agttgataat tacttctatc    293520
     gttttctatg ctgcgcattt ctttgagtaa tacagtaatg gtagtagtga gttgagatgt    293580
     tgtttgcaac aacttcttct cctcatcact aatcttacgg tttttgttgg ccctagataa    293640
     gaatcctaat atatccctta attcaacttc ttcttctgtt gttacactct ctggtaactt    293700
     aggtaaatta cagcaaatag aaaagagctt tttattcttg atttttgttc tttcggggaa    293760
     actgtataaa acttccaaaa aggaaaagta aaacaataca tctccttata tcaaagaaaa    293820
     tcaagaagga caacatggat gatatttgta gtatggcgga aaacataaac agaactctgt    293880
     ttaacattct aggtactgag attgatgaaa tcaatctcaa tactaataat ctttataatg    293940
     tatgttttca tttcaaggat agcctttgaa tcaatttact aacaatactt cagtttataa    294000
     tggaaagtaa tttgactaaa gtagagcaac atacattaca caaaaatatt tctaacaata    294060
     ggttagaaat ataccaccac attaaaaaag agaagagccc aaagggaaaa tcatcaatat    294120
     caccccaagc acgggcattt ttagaacagg tttttagaag aaagcaaagc cttaattcca    294180
     aggaaaaaga agaagttgca aagaaatgtg gcattactcc acttcaagta agagtttggg    294240
     tatgtaatat gagaatcaaa cttaaatata tcctatacta acaatttgta gttcataaat    294300
     aaacgtatga gatctaaata aattcgtttt caatgattaa aatagcatag tcgggttttt    294360
     cttttagttt cagctttccg caacagtaaa attttataaa ccctggtttt ggttttgtag    294420
     agtggttgac gaataattat gctgaagtac gtggtgacgg atattgggaa gatgtgtttg    294480
     tacatttggc cttatagagt gtggtcgtgg cggaggttgt ttatctttcg agtactgaat    294540
     gttgtcagta tagctatcct atttgaaact ccccatcgtc ttgctcttgt tctcaatgtt    294600
     tgtttatata ctcatatttc tatgtgttta tacaattgct attgtttata taatgtagtg    294660
     acattttctc ttaatcttat actaatttct atgacattta tataagaaga gacttatgat    294720
     caacataatt ttgcaaactt tgagagaaat atgtctttct actgcgataa agttattatt    294780
     tagattacat gtcaccaaca ttttcgtata tggcgatata atttatcatg ttttggtatg    294840
     ataatttaat ttttaaaaaa acaaatttaa ttgacctcat taattaatat ttattaatac    294900
     ctttaaatgt tgaggtaaat agctattttc tctcttcttt tcctttagtt ggaatttgca    294960
     caagaaaatg tttttccaca cactttagcg ttttttccta aatgttggaa taaaaaacaa    295020
     ctatcatcta tcaactagta gtcacactac caatgtgtta tcattatact gtgttaaaca    295080
     atgacataag gtatgaaaat ttgtcaacga agttagagaa agctggatgc aaggattgat    295140
     aatgtggtag gaaaatgaaa catataacgg aatgaggaat aatcgtaata tcagtatata    295200
     gaaatataga ttcccttttg aggattccta tatcctcgag gagaacttct agtatattct    295260
     atatacctaa tattattact tttatctaca atgcaacccc acaataatat aaaaattcac    295320
     caattccgca tctgcagatt actttcctaa atttgcatat agaattgtca agcgcaaatc    295380
     cgacgtcgat tccgcggcgg atgggtcatt ctaggtcatt ctaccaattt tatttgagac    295440
     caggtttatt caaccggtaa catagaaata ttcatacaat taagcttcta tggccaagtt    295500
     ggtaaggcgc cacactagta atgtggagat catcggttca aatccgattg gaagcatttt    295560
     ttatcacgtt attcggtgac acccaggttg ccgccgcgtt cgcgtccatc gtcatctgaa    295620
     aaataatgaa tattaatgga ccttgtgccc cataaaggtt ccatgttcca taagtcttca    295680
     ataatacttt tgtatattaa atttaccgtt attcggagat ctcttacggc ttatgatttt    295740
     ctttacattc caggccgcct tttgatgaca ttcagtgcgt cacgacgcga atagggcttt    295800
     gaaagcctta atgtggagta aataaatata tgaatgcaat aagtaaacat aagacgagtt    295860
     cttctatatc cggtgtacct aataatatag attttgccaa caatggaatc tcattaccca    295920
     tcccaagata aaatattgat caaggcatgg gccaccaaca taggaatacg caaaatagga    295980
     ttgatatttt tacatattat attatctttc ttcttctgtc tcaaatatag ctcttctcct    296040
     atttaaaaaa ttatcaattc ttgaatctca acttccatta aatttgatga ttgtttccca    296100
     atatcgatgt catcttttta cactgtaaat tataatttac taggaacatg aatactgatc    296160
     aatggatgat agttgattct tattgcaata aaaagtactt tctaagacgc taggacttct    296220
     aaacacagat attatgaaaa tgccaaaaaa tacagaatat tttccttctt ttcactataa    296280
     caagtagtaa gaaattaagc aatatggtaa tttgagctta tcagataaaa gatcctggta    296340
     gtcttgcaaa ggtgtgagta cttttgatga aactaagttt cagcgcagct atttcaattt    296400
     tggaaccttt aaagaaagtt taatcgaaac attgaacgat ccaaagcaca actttgtagc    296460
     gggaagtcac aaacaaatat aaaaagtgtt aataaactgc catcctatgt tagaattgtg    296520
     aaactttttg gactaataaa aggttttcaa catggtgttc caaagcactt atttctaggt    296580
     tagctatggt aacgagtttt aacgtaatca aaacaatata caattcaaga tctgtatcat    296640
     ttacactaac acaccccatt ttaatagagc tgagtacttc ctacatttct tttgcatatg    296700
     atatcgccac tgcatcattt ctgtagtcgt aaaatttcct tctcattaag acaccgaaaa    296760
     tagctaagga ttataacaaa acaaacaaat gctcaaacaa aacttttagt aaatcttttg    296820
     aaatgtaaaa gttacttaga ataactaaaa aaaaaatatt acgctatacc atatatttcc    296880
     attcccaatt ttatcgtttt ataataatat tcagtttcaa gaacaatgaa tatatttcaa    296940
     acattacatg cactcttggg agtaagctgc atcataataa attaaaatta acgctttaga    297000
     aaaagaaatt ttgaggttaa aggatggagg aagaaatcga taccaatttc aactttgatc    297060
     gacctgtctg actgaaatta tttctgcgtt tttcttacta caattagtac cattctcttc    297120
     aacttcaata gttctaacca ttgattcttc atctgtctca tcaaatccca tcttaccagt    297180
     ccagccattg gataccaaat agttgtgaaa ttcaacgtct tgcttcatta aatcgctttc    297240
     aagagaatgt ggaacaaaga aatatgtaat aatgatacca ataagaccac aaattgcagc    297300
     aataataaaa gtccatcttg cacccaaatt atccctaatg ggttggaaac attcgacgcc    297360
     tactacagaa ccgattttac cagtcacagc agataaacca tagaaaacac ctctaacagc    297420
     ggttgctgac gcttcactac taataacacc aagcatatca cctggtccag cattacctaa    297480
     catattcatg aatgcgtaga agataataaa caagggggtg atttttttca attggtcgta    297540
     cgcacatcca atgattagac caaagatgat gtacccagag aaaccaaaca tcaacgtata    297600
     tttacgacca atacgatcgg acagataagc accaattggt acacccagta cagctaaaac    297660
     tcccaacagt aagttccact ctgccacttt tactaaatca ttttggtcct tgataacgga    297720
     actgataatt gttgaactga aaataccatt tgggaaggta acaaaatcat acataaacca    297780
     tgtaccacat gtaccaagta accttttcca ataaaatttc aatgctagga aatatggtat    297840
     atttctcttg attctacctt tttcatagac ttctgtagta gcagtcttcc atctaaaata    297900
     gaacacactc aatggccaga agcaccctat tgcaaaaaca gtcctccaga tcgcctctaa    297960
     atgttttgtt cctgaacaga ttttgtagac gattaaaaag atgatcgtag caaatggacc    298020
     accgaaggct agtggcaaat ttgtcaccat aaccaggata ccacctcttt tggtagtggt    298080
     atattcatta gcagactcat tagcacttaa tgtactggta ggatattctg caccaacacc    298140
     aatacctacc aaacctctca taactgttaa catccaaaac atgccaggta cagtagtacc    298200
     gtgagaggca gcacacagag cactaccaat aaccaagata gcagtggcca caaggataca    298260
     agattttcta ctataataat cagcagcgat acccataaag aattggccaa aaataatacc    298320
     aactagggct gcgttggaaa ctctagtcga cacttttgag ctatagtttt tcttaccgta    298380
     ctccataaca aaaaccttgt ttagcatact cattgaacca tttacgtaac catcacttat    298440
     cagagcaaaa ccggacgcaa tgattgtaac tatgtttttc catttatctt tctttgaggt    298500
     ttcagtacgg gttgcacgcc tctcggcatc atattttatt attctaggat tagtgttctc    298560
     gttcacttcc ttctcattta ccgatgtgat atctttgtct tccatttttt atcctattct    298620
     atttttttga ttataagcaa aaagatcaac tcacgtctgc ggctggttga ctagtcacaa    298680
     gaaacagata ataaatactg taacgaacat ctgctacaac tacattcatc ggggtttata    298740
     tattcacgag tttcctactt catccagaca cattctggat gtcttccagc agatgtccct    298800
     catcaaagaa ttaagatagc cagattgaaa aactaggtta accagagaac taagttaact    298860
     aatgttggaa aataatccta cgatacagtg gacggaatgc ccatatgcct atataatcaa    298920
     tccatgctaa ggtgggggtc cagtaaggaa attcatgaat atgaagataa atgtggcacc    298980
     aaacggcaac gcggaagacc gtaggatcca atcatataac ccctattatt ctaacatcat    299040
     tgctgttggg tacaacattc tacgccgcta ttactacgtg ctgcttcttt tgattctctg    299100
     ctttctttac cgtcatgcac gtgcgccgcg aaaagtatta atcatgcgga cactctggca    299160
     tttaggggat actgtcaaaa agactatgct caatactgtc atattcatat gcacgttctt    299220
     tttttaattt atcttggcaa aacgtggggc tggaactttt gaaacgcact gcaacatctg    299280
     tggctgtaca gtcaagaaaa gtaagtactc atcgtcatgc tctaatgtgt atatggtatt    299340
     tgtggtgcag acaccattag aagtatagtt cacgaaatga tgacacgata gcatgtgctt    299400
     ttcgacggct gataaccttg tattctctta tttttgtatt cttttcgtaa gcggcatttg    299460
     tttgcagaac cttatcgcag atatcgataa acatttgttg acaattcttt ttcgctcccc    299520
     ttctttttgt ttatcttcgt tatattcaat agtctacata cactaaccgt tgaattgttg    299580
     caaacaaata ctaataaaaa tctatatata gtaaattgaa gatgtactga tcagtctatc    299640
     attgtttagt gcacccagac tcgaatctta aataccactt tacacaccta ctaaattttg    299700
     tcctcacaaa atgaagacag gattcaaaac cgattaatag tagcagaaac taaaaaagta    299760
     cgaatattag taaaattcat gttcttgaat cgagctacta tctttgtcgg gagggtaaac    299820
     gattataact caaaatgact ggaactggtg attattaatt tttacgtttc ctgtgccaat    299880
     aagcggaaga taagaggata gaagaaaaga aaggcggcac ttggcgaact acaatggcga    299940
     ttatattcat ggcgattata ttcatacaaa ggtaatggag gcctcggata atggacaata    300000
     ttgagaaaat ccttatgctt acttctctta ataaaaaata gacacagcca tttattatgc    300060
     gtaaaaaaga ttacccactt gtcttcgatg cgtgctgctg ccaatcaacc ttttgagcgg    300120
     aacttcgagc tcgcaatgcg tctggaatgt tgctagagac agtcttggtt atctgtgaca    300180
     tgtgtttcgt tcaggcgtgt gagcatcttc ttgttcgatt tcaaaattac cgccttgact    300240
     cgtgaaactg gataattcgt tggcgttttc atataagtcg tctgatggcg aaaacttttc    300300
     ctttacttag catacagcaa atatccccat ttgacggatt tttgaaaaat gagcccgcta    300360
     acccagaatg aactgcatta ccaagcattt atgtaaacgt tccgccacca tctttggtaa    300420
     ggtatactat tatgttctgg atttaaggtt gattcacaat ttttcatcac caaaatctgg    300480
     tggcatgcct agttgtctgg tttcaggcaa tttagccatc atagaaaagc atcctctgtc    300540
     ttgagttgag aaaatgttac tcatagagcc aaacaaataa accctggaat taaaatatag    300600
     tttaaacaca acttcatatt acactgtaaa tacatatcac aataataaat taacgaaata    300660
     gtaagacctt atgtttctat atgacatcag tcccgaatag tgtcaatttt ttgtcgtcag    300720
     tgtcgaacat ttttactgtt tattcatcat atcgtgaggt atgtaggcat cttctattga    300780
     cttaagcatg ataaaagatt cacccaaaac tgtatcgaaa tattgataaa attaaatttc    300840
     aaagtcaaac ttgttttcaa tggttgctat tttcttacca ttcgagctct ccctcaggat    300900
     tttttcacat ggaatgttca tggcctcaat ttccatgggc tttttgcatt tatctccttt    300960
     aattaattgt aatggctcta atgatacagt ttcgccatta gctttgtcac atatatcgga    301020
     aagggcaatc tgatcataat ctggtataca gtcacccttt gcatctctaa caaattcaga    301080
     agagcattcg tagtcggatt cagtacaact gtcacaaggt atttcatgca aaatcatatc    301140
     tttgaatgtc ctttttacca aacaacgggc gtcctgtttc ctccttttat acatgtattt    301200
     ggcgccatta aggcatttcc catctgccaa attccagtct tcgaaatctt cctcttcaca    301260
     cgttttatag tcaaaatgca gcagaaaaat cgatcgcata caggacactt cttgcaatat    301320
     atgagatgtt ggtgttgttt ccttcttgac tagccgtagt aatgagatgt ccgcttaaaa    301380
     taaattttga gcctgatcca tctggcgttg tattaatcaa ctctaatgga tggatataaa    301440
     ataaagcgtc aacaagctca tattgattcc atgttctacc ttggtccaag gaaaaataaa    301500
     gtttggattg tacatcacca tctttatatg aaggagacgg gatatataca ataatatttc    301560
     ccagatcacc agtagcatat aatccagaag aattatgggc caccctccat gttagaccac    301620
     cgtctctaga aatgaaagtt tttcggtcct tccgatcgaa ttcattgtca tcgccaacag    301680
     aacctgtcat taatatgatc ccagcagaag gatttgaaag ttttagattg taaaaataac    301740
     cctgaagtga acatctctca ggcctagtga tatcacagcc gaacgaatcg gcattttctt    301800
     catcaacaac tttcaaattt gaccatgtga ggccgttatc aacggatatt ttggtttctc    301860
     ctccggctat attttcagta tagtttactt ggtgattaga atagtcaatg gaaggatgaa    301920
     acgatccaaa tattgtccct ttcaagaaat caggaaaagt gagcctaaaa tttccaaact    301980
     gatggtttgg tgtccattca acaggtgaga atttcaaccc ttgcgaatct gatatgaaaa    302040
     tctctgagag atctggatca gcattttcct catttgtgat ttctgtcgat ataagaagga    302100
     tgatccttcc gatagaatct tcacgaattt taatcacttt gacgtgccgt aattgagtag    302160
     gcagctgtgc cttttgaaaa gtagatgcat cattggatat ccagatgtcc gtagatgaca    302220
     tctcgttatg cccgtcatct tgcgttaaaa cgaccacata tgacttcaat atcttgtatt    302280
     gagtaacaat cttatcttta aattcatcaa aatctttaaa cgttttgcct ccatcactac    302340
     tgaaagccaa ctgtgtgtag gtagcagtta agcgatattc ttcatcgtat tcacggttag    302400
     agaacaaaca gagtatcgaa gtatcattac cagtaaagtc agaatccttg ctagacttaa    302460
     tgaaatgaca gctttaagtt gttatatcgt cgtctttttt cttttccaag gaaggtttaa    302520
     ttttaaaaaa ggattcccat cattgctcaa gtaaatttca cttgggtcat ataaaacgtc    302580
     tgcgtctatc atatagctat agcaattcgc aataagaagt tctttgtttc taggatgagt    302640
     agttataaaa cagtcgccat ctaaatattc ttctgatgag ggtatagtta aagccctcca    302700
     tgactcccca cggtcgtcgg taatgtagaa tttgggtgat tcacatataa aagcgaaacc    302760
     tctttcctgt ccatggaaag gatcaacagt aaatctgaaa atgcgctctt caatttcttt    302820
     gaccgtttcc caattttctc cagcgtcgaa acttatccat acaacccccc aaccatctaa    302880
     tctgatagaa gtgttggaat catcaaaact cactagatta aatgatgttt ctataggagc    302940
     ctccgttact tttgggacaa atttctctgc attgagtagc ggaagtagta taattaccca    303000
     aagagtatat atggcatgaa gtaatatcat aattgaggat ctcttacctt ttcttagttc    303060
     aaagtttttt ttcaaagctc ggaactttat gctacaattc aatgactaaa aaaaaggtag    303120
     cggataatct tttggttgca aattggcggc atttaaatat attttgggtt gcaagtattc    303180
     taaaaatatt ctcataatat tctaaaaata tccagtctag gtaattgcaa ttattttgag    303240
     tccggtgact ttgagttgac catgttcact tcctgtacag ccatcaaggt aacgtgttta    303300
     ccatctaatg gagaaaacca agagataaga ctagaaacct agttaggata cttggatttg    303360
     ctaatgtcgc cagtagtacg ataataccat aaagatacgc tgttgaacct gatttgtata    303420
     tttaaagaat gggaatcttt aagggatcat agtctagaat ggtattctgc agaatagatt    303480
     ttaaatggtg aaaactttcc ctcactatgt ccaattgatg ctttttagga tgacgttaga    303540
     attttattct ggtgaaggca cttttaatat gaagattcgt tgaagtatca ataacctttt    303600
     attggcatac ccttacctaa ctggtctctc tcacctcgtg atgttacgaa cgccacgatt    303660
     attctcaaac taggtaaaga ttttttcttc aaaattagtg ggaaagactc gacagacccg    303720
     cttaccaggt attctttcta aacaataggg tttaccagta cccctgaaaa tgataatgcc    303780
     catgtgcggc tgatcgcgtt aactacgtat gcagttgaat caaagccata ccacagaaaa    303840
     tggtacaaga gcccactgga tagaatagtg ctggctatca aaccaatatt ttctttccag    303900
     ctcttggggg acctctactg cgttatatcg tagtttccat tcagcctgct tatcgcctta    303960
     ggaaaaggga atgtaagagg cagaaaagtg cggcgcaatc gttcggacag cgagccgcta    304020
     ttataggtaa gaattcttaa agagcttcgc cggatattat tacagtgtat taaatttcgc    304080
     caagtctttg ccaatggaaa taggtgcata attttatgtg cttggtacat atgagttcaa    304140
     tagatatgta gtagttggat agtagatagt aaggatatat aatcatggaa gggtgacgca    304200
     caacaaatca cataatgagt tatgattttc actgttctca tctgtttccc ctacaaggcg    304260
     tgatcaataa caaacaattt cattaaaaaa aaaaaaacca agtcactcta acatacgtaa    304320
     taactgtgta tacaaaagaa aaataatatc tgttcgtcat ctagtttaat acggcaacta    304380
     gtttttcacc agagttctta ccgattttaa tgtcttccag gatacgagga acatcgtaaa    304440
     gcccgttctt atagaccctt gctggaatat ggtgaatttg cccatcacta atctttggat    304500
     tgatgaactt gacgaattcg gtggcagctc tcctggcttc tgggtcagca gggaaagtaa    304560
     tgccaccaaa tggtacttca tggccgccta ttgaatacag tcttgttctg tcaatagtga    304620
     cattttgcct cctattctcc tttttgacgt tttcttctgt caaattagtt aattcgacaa    304680
     cggtagcatc ctgtttatcg gccgcacatt tgtacacttg ttgaagcgta ttttgattcg    304740
     cgacacagtc gactaaatac gagatattgt tgtacttgtg tttaatttgt tctaccacgt    304800
     caatatcatg gtaatcaaat agttgatcag caccatattc tttcaacagt ttttcgtgtt    304860
     tccgagaagc cacaacaatg atcttggtga agccattcaa tttattggct aattggatga    304920
     gcgactgacc tactgcagtt gcaccgcccc ataataagat ggggccgttt ctttgtgggg    304980
     ttgatggctc ccacttcagg ttcaagccca agttataggt caacaccaag ccagctgtgg    305040
     tcagtgacac tgggatagtg gctgcccctt ccaaagacct gacagggccg gcaggtagaa    305100
     catcttcacc caaaaatttg agttcattgg gtgatttgta ggcaaccaca gttgaaatag    305160
     cagaatattc agcaaaagca ccattggaag gaaaccttac ggaagatccg tgaatgaacc    305220
     cataaatata atcaccaata gaaaagtctt taggatcgac ggctgggccc aatttgacaa    305280
     tttggccggc agcgtcacat cccagaatag atccttgagg cccgaccttg tagtcaatgt    305340
     gtgcccaatc agtcgggtta ccagcaacag cgagtgtctt aatcaatacg aatccttctt    305400
     ccaattcagg aatgggaacg ccctctttga caaccgcttt accgtcttca atgacgacag    305460
     ccttcatggt ttctggaatt gcaacttgcc tgtttgtagg ttatatgtaa ttgtcgttga    305520
     taatctgtat tcagcttgcc attttataga atatggttag aaggatctta agctagataa    305580
     agaaaaagaa aaaaatagaa aaaagcctgc ccgctttata agaacttttc tcaatatctg    305640
     ttgaggaaca cttagtaata ttgtctatca tggttgcttt attcttggtg atattactct    305700
     ctgggattcg atgtgttctc atcatctgaa gggtttccta tgtgttgaaa gcctatccca    305760
     ctagacggag ccgcgcgcca gccgggcgga tccgagacat cttagtcagc tgagacaaga    305820
     aaggcacagc tctcggacag gaactgctgt catatgaaaa cctaaaaatg tttcctggaa    305880
     attccatgac tgcgcaaagt ttgatacgtt tattgttctt ctctactacc gcactttcta    305940
     tctcggaaac ctttcaactg aatgaactat tgttaattgt atggcgtgtg gccttgctat    306000
     ttcagcaaat ttagagtaaa gtaaactccg tcggaccagt atagtaacga aacaagccat    306060
     tgattctgca gcatattgcg accaaaacct ggaaattggt ggctatgagt tttaatttat    306120
     aattatatga agacaaagct tggaatgctg agtacttttt cttcaatgct gctcactgcc    306180
     cagaagcgtt cagaacaact ctactggagc cattctgctt gaaggaggat aaaaatgcca    306240
     agatcaagtc ttttaaagac tctatccctt ttcatcggaa aagcactaca agtttattct    306300
     acagaagtgg acaaactgtg gaacttgatc catactgagt aagtatggaa gactgttaac    306360
     ttggaggatt tttctctgct ttctaaagaa ggttcactgc tttacactca cctaggttct    306420
     catgagtatt gctagctagt gcgagtttga tctatacttc acagactttt aacaccccgt    306480
     tctttaagtt ttccctgatt atcaagcgga tttccaattc ttattcccca ctatcgcacc    306540
     tttcttatct gaattgtatt tttgagtggc ctaactgtaa tcttttattt tgttttctaa    306600
     ttattgaagg cggtttctcg aaacatttca cgatttccaa aattcaagaa ttgaaattat    306660
     gaacatagaa gacaaaatgc cttttttatc aactattatg aattctctag aaagtggttg    306720
     caaaggaaat aaatatgtat ttgctgagag gaaaagtttg gaagaacaaa aagtatttct    306780
     ttgatggagc tgattatcaa gcattcttta cggggagctt tcgaaatttt ttatattcaa    306840
     ggacatttat gttgtgtggg ttattaaacg tgggactttg gaaatacatc caagaagcac    306900
     aattgagctc taacgatgaa ccgttaccat aaagatagag acatttcttt tgacttagaa    306960
     gctacatgga gtaccaacta ttaatacacc tctcctagag aacattttta aaatagaata    307020
     aaataaagta gcgctctcaa ctacccttac acttttttcc ttcatatctg gctagaaaag    307080
     agggattaca tctcggaatc aaagttttaa tactgctact acgaactggt tacaattcta    307140
     tttttatcat acacgatact ttgaacatca acttctctca ataccatccg ccttcagcgg    307200
     ctacaattac gtaattgcac caaggcattc gccgagagtt tacatatttg cagaccctaa    307260
     cagtatacga ctcccaacac acgtttaatg ttgtacgaat tcaagagatg gaaatatttc    307320
     ttccgcggaa gccgtttaaa gcagactgaa tttaggctta gacaataagc ttctgaacga    307380
     gggtccaaat ctaaaattcg gatattcttt ttgaccgaaa gcggaaactt cacaggcgcg    307440
     cgtaaaaggg tttttcaagg caccccggca cccctataat tggcattccc acattctgcg    307500
     catacgaata cacatgagtg ccataaaaca atactccaca tacgaaacct atgaaagatg    307560
     tatgattcgt tcagaaacaa gagcatctcc atagagataa tgagattgtg tgaaagatga    307620
     gatatggagg atatgtgagg tgctaaatga gcgtctgtta acgaatcgtt taagtagtga    307680
     tgacagatgg aggaacgggt ataaatagag ctgcttcaac tatatgcctt tgaggtatgc    307740
     gctttcattt cactatttct tgttaagatt acatcagcac taacaaacaa aacaaataca    307800
     atggtcaaat taacttcaat cgctgctggt gttgccgcca tcgctgccgg tattgccgct    307860
     gccccagcca ctaccactct atctccatct gacgaaaggg tcaacttggt cgaattgggt    307920
     gtttacgtct ccgatatcag agctcatttg gctcaatact acttgtttca agcagctcat    307980
     ccaactgaga cctacccagt tgagattgct gaagctgttt tcaactatgg tgacttcacc    308040
     actatgttga ctggtattcc agctgaacaa gtcaccagag tcatcactgg tgtcccatgg    308100
     tactccacta gattgagacc agccatctcc agtgctctat ctaaggacgg tatctacact    308160
     gctattccaa aatagagaca tgcctttact aatgaacttc catagacatt gaaaaataac    308220
     gaaagaataa aaaaaaaatc tttttttttt tttgatataa atacagttga ctatataaac    308280
     atatatcaat actataagcc tatatttgat caagacgaca ttatttaggt gcatcaacaa    308340
     cggaaaagaa actttcttct aggctatcct tctggggaag cagttgaaag tgctatccag    308400
     tattattgca tatattctta atgagtagtg ctgaagtttg atacgtttgg ctctgttgct    308460
     tttatttctc ccacgaaaat aaattgattt ctttattttt cagtgtgttg gcccggagtt    308520
     gtttacacac atgtctcttt ttggattaat gctgtagatc agggactatg cgagcgacaa    308580
     gtcagagtaa ccatattgaa ttttcgtctc ctgttatacg aatatttgca tttctgtgcc    308640
     tacttatgtg tgtatatgtt tttattagtc agaaaatgga gtaagtgtta aagtaaggat    308700
     agtgttaagg aggtaataac taaagatttg taggataagg cggtgttatt tgttgcaatt    308760
     ttctcagggg tggagtggaa atggtttgat tcaattatca gttaagcaag gaagagttga    308820
     agggcgaaca tttgcaataa tcccaatgtc atttaatgcg ggtcggctga gacgctcaat    308880
     attcggccga aaagtatcat tcggccgcat aataaaatgg aatagaagat aaagcagatg    308940
     tcactaattg agcaccaaaa ctctgagtag aaattatata aagaagcacg aacatgacct    309000
     gctttagatg ttgcttgata ttattgaaat aaaaaaaaac atagaaccac tgaaaaatac    309060
     aaaaaaaaaa tgctttaccc agaaaaattt cagggcatcg gtatttccaa cgcaaaggat    309120
     tggaagcatc ctaaattagt gagttttgac ccaaaaccct ttggcgatca tgacgttgat    309180
     gttgaaattg aagcctgtgg tatctgcgga tctgattttc atatagccgt tggtaattgg    309240
     ggtccagtcc cagaaaatca aatccttgga catgaaataa ttggccgcgt ggtgaaggtt    309300
     ggatccaagt gccacactgg ggtaaaaatc ggtgaccgtg ttggtgttgg tgcccaagcc    309360
     ttggcgtgtt ttgagtgtga acgttgcaaa agtgacaacg agcaatactg taccaatgac    309420
     cacgttttga ctatgtggac tccttacaag gacggctaca tttcacaagg aggctttgcc    309480
     tcccacgtga ggcttcatga acactttgct attcaaatac cagaaaatat tccaagtccg    309540
     ctagccgctc cattattgtg tggtggtatt acagttttct ctccactact aagaaatggc    309600
     tgtggtccag gtaagagggt aggtattgtt ggcatcggtg gtattgggca tatggggatt    309660
     ctgttggcta aagctatggg agccgaggtt tatgcgtttt cgcgaggcca ctccaagcgg    309720
     gaggattcta tgaaactcgg tgctgatcac tatattgcta tgttggagga taaaggctgg    309780
     acagaacaat actctaacgc tttggacctt cttgtcgttt gctcatcatc tttgtcgaaa    309840
     gttaattttg acagtatcgt taagattatg aagattggag gctccatcgt ttcaattgct    309900
     gctcctgaag ttaatgaaaa gcttgtttta aaaccgttgg gcctaatggg agtatcaatc    309960
     tcaagcagtg ctatcggatc taggaaggaa atcgaacaac tattgaaatt agtttccgaa    310020
     aagaatgtca aaatatgggt ggaaaaactt ccgatcagcg aagaaggcgt cagccatgcc    310080
     tttacaagga tggaaagcgg agacgtcaaa tacagattta ctttggtcga ttatgataag    310140
     aaattccata aatagtctat atacgtaata tttttcagaa tctcttaaaa tgcatgtcaa    310200
     atctcggaat ttatcatgac ccattacata acaagagaaa agtggtttgc attgtatgta    310260
     taccttaaac caattcttcg gtagtcacat gacctatata tagggacatt catttcttga    310320
     ataggatatt tcttaaactt aagggaaatt ttgatgaaaa tttagaatct ctcgacaaca    310380
     gtgcagagca gtaagtttta ttcaatacga aatgtgtgca gggttttacc cattcatgtc    310440
     gagtacgtct acatttgttc tgcgatttaa cttaatactt agcctactca tatgtatcga    310500
     agccaaacta ttaaatctga aaactgaata cccattaagt aggtacatta atgcaatttt    310560
     cgtccgaaag gtagagtgtt aatcatgctt ttacttcgaa atctagagtc cgagcatgtc    310620
     tgatgaggtc ctcttaaagc acttcaattt taaaagagaa gagcgcaaat ttttacaaag    310680
     aatgcctata ttaatatact gtgctatcta agaggatggt tcaatggttt gaaatgagtt    310740
     gaaaaataaa gatttacata gtagcgtgta ttcttcacat ttttgcattc ggtagatttt    310800
     ctactcaaga cccgtgcaga tcactattac actcattatt acaagtcatt gagaacgaaa    310860
     ttttgacatc attactaata atgttactca ttaatacttt attaatgtaa gcggtagata    310920
     aacaaatgaa catgaaattg gctgctgaaa tgctctgatg gattcgatta cagtaaaaaa    310980
     acctcggtta agattggttt gcctgcaatg caaaaagatc aaacggaaat gtgataaact    311040
     gcggcctgct tgctcgcgat gccaacaaaa ttcattacag tgtgaatatg aagagagaac    311100
     agatttatct gccaatgttg cagcaaacga ctctgatgga ttcaattcct ctcataagct    311160
     caatttcgaa cagcaacctg tacttgaaag gactgggctt agatattcct tacaagtgcc    311220
     tgaaggtgtc gttaatgcta cgctgtcgat atggaacgcc gaagatatgc tagttatagt    311280
     aggattagtt acatttctgg attatccttt tgctgcgcat agtctggcgc aacatgacca    311340
     gtatatcagg gcactttgtg cttcgttgta cggcatggcg cttgttgact ttagcaatta    311400
     tgctaatggt attccttgtg aagacacatc aagaagtata ctaggaccat tgtcattcat    311460
     agaaaaggcc atttttagac ggatagaaca tagtaagcaa tttcgagttc agtctgccgc    311520
     cttagggtta ttatacaatg cattttcaat ggaagaagaa aacttctcga ctcttctacc    311580
     gtcactcatc gctgaagtgg aagacgtgtt gatgcaaaaa aaagactgtg aaatactttt    311640
     gaggtgtttc tatcaaaata tttatccctt ctatcctttt atggacattt cactctttga    311700
     gagcgatctc actagtttgc ttttacaaga cgacaataat cgttggaaaa ttagtactga    311760
     agttaaaaat gtgcgcaaaa aaatagaaac tttgtcatta cttacaatag taatggccat    311820
     ggccttgatg cattcaaaat tggatgcaaa tcttctttca atggtaaaag aaaatgcctc    311880
     cgaaagtgcc aggaaacttt ctcttttatg tcataaacta ttatgcctcc tggatgtatt    311940
     tcgctatcca aatgagaaca cttttacttg ccttttatat ttctacgttt cagagcattt    312000
     agatcccgag agtcccgatt gtgtactgag ccccactaac ttgcttactc tgcaccatct    312060
     tttaaatttg tccatgacct taggtcttca atatgagcct tcgaagtaca aacgtttcaa    312120
     agatccagaa gtgataaggc agagacggat attatggtta ggagttcagt cattactttt    312180
     tcaaatttct cttgctgaag gtgatgctgg taaatcaaat agtgaatata tggaggcata    312240
     tttaacagac ttcgaagaat atattgaagc ttcctcagag tatgaaaaaa gttctgcgag    312300
     tgaatcgaac gtgcaaatga atgatattgt ttggaataag tacaaatttc acgtcatttt    312360
     gagtaaacta atgtctgatt gcacttcagt tatacaacat ccgcagcttt tccacatttt    312420
     aggaaatatt aaaagatctg aagattttat ggctgagaac tttcctacaa gttcgattta    312480
     ccaacccctt catgaaaagg aaccaaatgc gatcaaagtt ggcaaaagta cggttctcga    312540
     tgtcatggat attcaaaaaa ctgaaatatt tcttacaaat attgtgggaa gtatgtgttt    312600
     tttaaacatt tttgatgtcc tatcgttaca ttttgaaaaa aaatgtgtta tgcactggga    312660
     agaatatgaa aagaactatc atttccttac tttgaaaagt ttcaatgcat acttaaagct    312720
     agcagggttg atatctgatt atctcgagaa taagtttcaa gggaacattt tagagagtcg    312780
     cggttatatc atagataaac aaatatgttt tatgcttgta aggatctgga tgttccaatg    312840
     tcgtattttg ttaaggtttt catacaagca agaaagtcag aaaaaattgg cctcttccag    312900
     tatatccact aacgataatg aaaaagaaga tgaaatgatt gtcattttag aaagacttat    312960
     taaacacatt cgtaaccaaa tggcacattt agtggatcta gcaaagggaa aacttcaaga    313020
     tagttacttt ggtgcttacc aaactgttcc catgtttaga tacgttgtgt atttgatcga    313080
     tgttggcggc ttagtatctg tgacaaatgg gttttgggat aagatttcca gtgatggtga    313140
     aataccgcca aaagtacaac aagccgtgag attgaaatgg ggattggact gcaataattc    313200
     gagaagaatc aaacaaaagt taataagcag ccagagtttg cagagtttca atcaagttct    313260
     gttgtgccag atggaggatg cagttctctc cagttccttc gcaataaaag ccaataccgc    313320
     tatgtcccaa aacacggctg aagaattttt caatatcagc gaagaagagg ctttaaatca    313380
     actattggaa aacaacaatt ttgatgcctt ctgggattta ttaggtgaaa atctgagcga    313440
     tatgccttct ttgtgagaat acggatattt ggaaaggcta aaaaaaaaaa aacaagccaa    313500
     aaacaagaaa cactgttatc ctccacgttt tttccactgt tttaagactc gacaagacgg    313560
     aaagattcct cacatttcgc agtgtttctt ttaacctgct cgtcaatttg aaaaaatgag    313620
     catggttagg caggcggaat gtaataggtg cggtgcgtat aaataagtat ctcggccgtt    313680
     cctctattgc gctcggccga gatgtcctac atgcataaaa tagattaaaa aaagggatca    313740
     cgatactcaa atatgcatat aataacaaca acacactttg cggtaaatag aaggataata    313800
     tcgtaatctt ttgctggttt cgatgatgac ttgaaaaaat tcaattactc tttcgatcat    313860
     ctagaagaag catatccatc gtgcttaaaa tgattgggtc cgcgtccgac tcatctagca    313920
     agttaggacg cctccgattt ctttctgaaa ctgccgctat taaagtatcc ccgttaatcc    313980
     taggagaagt ctcatacgat ggagcacgtt cggattttct caaatcaatg aacaagaatc    314040
     gagcttttga attgcttgat actttttacg aggcaggtgg aaatttcatt gatgccgcaa    314100
     acaactgcca aaacgagcaa tcagaagaat ggattggtga atggatacag tccagaaggt    314160
     tacgtgatca aattgtcatt gcaaccaagt ttataaaaag cgataaaaag tataaagcag    314220
     gtgaaagtaa cactgccaac tactgtggta atcacaagcg tagtttacat gtgagtgtga    314280
     gggattctct ccgcaaattg caaactgatt ggattgatat actttacgtt cactggtggg    314340
     attatatgag ttcaatcgaa gaatttatgg atagtttgca tattctggtc cagcagggca    314400
     aggtcctcta tttgggtgta tctgatacac ctgcttgggt tgtttctgcg gcaaactact    314460
     acgctacatc ttatggtaaa actcccttta gtatctacca aggtaaatgg aacgtgttga    314520
     acagagattt tgagcgtgat attattccaa tggctaggca tttcggtatg gccctcgccc    314580
     catgggatgt catgggaggt ggaagatttc agagtaaaaa agcaatggag gaacggagga    314640
     agaatggaga gggtattcgt tctttcgttg gcgcctccga acaaacagat gcagaaatca    314700
     agattagtga agcattggcc aagattgctg aggaacatgg cactgagtct gttactgcta    314760
     ttgctattgc ctatgttcgc tctaaggcga aaaatttttt tccgtcggtt gaaggaggaa    314820
     aaattgagga tctcaaagag aacattaagg ctctcagtat cgatctaacg ccagacaata    314880
     taaaatactt agaaagtata gttccttttg acatcggatt tcctaataat tttatcgtgt    314940
     taaattcctt gactcaaaaa tatggtacga ataatgttta gataattttt cagtaatcaa    315000
     ctacgcaagt aaagcagtaa atacgttact gctggtatta atgtcatgta ttgaggcaat    315060
     gatgctatgc tcttaacgac atgtagctta caaaacgttc ctatggtttt actgcatggt    315120
     atttacaaat tagatagcag ttccatccgc ccttgacata ttattattca gacaaggtgt    315180
     atatgagcat aaatatgtat atatgcacat gaggtttgta ttaaccttgc aactgtacca    315240
     aaatacaatc ttctttgctg ctatttaacg gcgtatgtgc agttcataaa tgcgtgttct    315300
     gtatagtaca tccgcgcaca ttcttcctag cggaagacat attaacgtag cccgtacgcc    315360
     ctggttaaga cttggtatag ttccaataat tggaatatta ctgcatagtg gtccaatagc    315420
     aggatttagc ataaacatga taatatttag agatgctttc atccctctga cgaaggtggt    315480
     agagaacaag aaaatgaata acattatatc atattcctat atatatatat atatatatat    315540
     atatatcata taacggtgga aaatcccggc gatattacag ataaacatta cacccgcatg    315600
     aatgtgagcc actactatat tataacttag tgaataaaga gtgttacaat agtgaggtgc    315660
     atattattct aatgtaaggt ctgtataagt acgaaatatt ctgaagtggc atccagtcaa    315720
     gcaaatggta atattaagga acttttaagt taatgacgtc atggtagtgc tcgtacttca    315780
     agtcaaagtg tttatgtatt atggttgaag aatagaatat ttttatgttt aggtgatttt    315840
     agtggtgatt tttctgtaat attgacataa gtgtatataa attaagtggt tagtatacgg    315900
     tgaaaaagag gtataacgta tgtattaagg gaatttatac gatatttggg cccgccgaat    315960
     gagatataga tattaaaatg tggataatcg tgggctttat gggtaaatgg cacagggtat    316020
     agaccgctga ggcaagtgcc gtgcataatg atgtgggtgc atttggtact gatttagtga    316080
     gaatgggcca tggattggag tgtgagagta gggtaacttg agagtggtat atactgtagc    316140
     atccgtgtgc gtatgcccca tcaatataag tgaaggtgag tatggcatgt ggtggtggta    316200
     tagagtggta gggtaagtat gtatgtatta tttacgatca tttgttaacg tttcaatatg    316260
     gtgggtgaac aacagtacag tgagtaggac atggtggatg gtagggtaat agtagggtaa    316320
     gtggtggtgg agttggatat gggtaattgg agggtaacgg ttatgatggg cggtggatgg    316380
     tggtagtaag tagagagatg gatggtggtt gggagtggta tggttgagtg gggcagggta    316440
     acgagtgggg aggtagggta atgtgagggt aggtttggag acaggtaaaa tcagggttag    316500
     aatagggtag tgttagggta gtgtgtgggt gtgggtgtgt gggtgtggtg tgtgggtgtg    316560
     gtgtgtgtgg gtgtggtgtg tgggtgtggg tgtgtgggtg tggtgggtgt ggtgtgtgtg    316620
//

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