(data stored in SCRATCH zone)

SWISSPROT: C0ZM57_RHOE4

ID   C0ZM57_RHOE4            Unreviewed;       392 AA.
AC   C0ZM57;
DT   26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   26-MAY-2009, sequence version 1.
DT   08-MAY-2019, entry version 69.
DE   RecName: Full=Cytosine-specific methyltransferase {ECO:0000256|RuleBase:RU000417};
DE            EC=2.1.1.37 {ECO:0000256|RuleBase:RU000417};
GN   OrderedLocusNames=RER_03260 {ECO:0000313|EMBL:BAH31034.1};
OS   Rhodococcus erythropolis (strain PR4 / NBRC 100887).
OC   Bacteria; Actinobacteria; Corynebacteriales; Nocardiaceae;
OC   Rhodococcus.
OX   NCBI_TaxID=234621 {ECO:0000313|EMBL:BAH31034.1, ECO:0000313|Proteomes:UP000002204};
RN   [1] {ECO:0000313|Proteomes:UP000002204}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PR4 / NBRC 100887 {ECO:0000313|Proteomes:UP000002204};
RA   Takarada H., Sekine M., Hosoyama A., Yamada R., Fujisawa T., Omata S.,
RA   Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S.;
RT   "Comparison of the complete genome sequences of Rhodococcus
RT   erythropolis PR4 and Rhodococcus opacus B4.";
RL   Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:BAH31034.1, ECO:0000313|Proteomes:UP000002204}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PR4 / NBRC 100887 {ECO:0000313|Proteomes:UP000002204};
RX   PubMed=16423019; DOI=10.1111/j.1462-2920.2005.00899.x;
RA   Sekine M., Tanikawa S., Omata S., Saito M., Fujisawa T., Tsukatani N.,
RA   Tajima T., Sekigawa T., Kosugi H., Matsuo Y., Nishiko R., Imamura K.,
RA   Ito M., Narita H., Tago S., Fujita N., Harayama S.;
RT   "Sequence analysis of three plasmids harboured in Rhodococcus
RT   erythropolis strain PR4.";
RL   Environ. Microbiol. 8:334-346(2006).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a
CC         5-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-
CC         homocysteine; Xref=Rhea:RHEA:13681, Rhea:RHEA-COMP:11369,
CC         Rhea:RHEA-COMP:11370, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856,
CC         ChEBI:CHEBI:59789, ChEBI:CHEBI:85452, ChEBI:CHEBI:85454;
CC         EC=2.1.1.37; Evidence={ECO:0000256|RuleBase:RU000417};
CC   -!- SIMILARITY: Belongs to the class I-like SAM-binding
CC       methyltransferase superfamily. C5-methyltransferase family.
CC       {ECO:0000256|PROSITE-ProRule:PRU01016,
CC       ECO:0000256|RuleBase:RU000416}.
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DR   EMBL; AP008957; BAH31034.1; -; Genomic_DNA.
DR   STRING; 234621.RER_03260; -.
DR   REBASE; 20612; M.RerPR4ORF3260P.
DR   EnsemblBacteria; BAH31034; BAH31034; RER_03260.
DR   KEGG; rer:RER_03260; -.
DR   eggNOG; ENOG4107R98; Bacteria.
DR   eggNOG; COG0270; LUCA.
DR   HOGENOM; HOG000226162; -.
DR   KO; K00558; -.
DR   OMA; GWAVNAV; -.
DR   BioCyc; RERY234621:GHDE-332-MONOMER; -.
DR   Proteomes; UP000002204; Chromosome.
DR   GO; GO:0003886; F:DNA (cytosine-5-)-methyltransferase activity; IEA:UniProtKB-EC.
DR   InterPro; IPR018117; C5_DNA_meth_AS.
DR   InterPro; IPR001525; C5_MeTfrase.
DR   InterPro; IPR029063; SAM-dependent_MTases.
DR   Pfam; PF00145; DNA_methylase; 1.
DR   PRINTS; PR00105; C5METTRFRASE.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR00675; dcm; 1.
DR   PROSITE; PS00094; C5_MTASE_1; 1.
DR   PROSITE; PS51679; SAM_MT_C5; 1.
PE   3: Inferred from homology;
DR   PRODOM; C0ZM57.
DR   SWISS-2DPAGE; C0ZM57.
KW   Complete proteome {ECO:0000313|Proteomes:UP000002204};
KW   Methyltransferase {ECO:0000256|PROSITE-ProRule:PRU01016,
KW   ECO:0000256|RuleBase:RU000417, ECO:0000313|EMBL:BAH31034.1};
KW   S-adenosyl-L-methionine {ECO:0000256|PROSITE-ProRule:PRU01016};
KW   Transferase {ECO:0000256|PROSITE-ProRule:PRU01016,
KW   ECO:0000256|RuleBase:RU000417, ECO:0000313|EMBL:BAH31034.1}.
FT   ACT_SITE     79     79       {ECO:0000256|PROSITE-ProRule:PRU01016}.
SQ   SEQUENCE   392 AA;  42672 MW;  B2A5C9581A349D93 CRC64;
     MRKGAVTSSR SMVGLFAGIG GLELGLSEHG WNTELLCEID PGAQAVLRSR FADVPLHGDV
     TKLRALPSDI ELVAAGFPCQ DLSQAGKTAG ITGARSGLVD EVFRLVKRKK GPRWLLIENV
     PFMLQLGKGA AMRHITDALE DLGYTWAYRV VDARAFGLPQ RRQRVIMLAS RTDDPREILF
     GQDAGERLGG DPADYPCGFY WTEGTRGLGW AVNAVPTLKG GSSVGIPSQP AVRLPSGEIV
     TPGLVDAERL QGFDPDWTLP SVEVPGLRHS HRWKLVGNAV SVRMASWVGG RLNDPIAYDA
     AGETPLEPGD AWPSAAWGRN RQAFRVHTST WPVQYDYEDL SGFLEDTRLL SARATAGFLK
     RARMGNLRFI PGFIEDVESH LERMGGYPEA AA
//

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