(data stored in SCRATCH zone)

SWISSPROT: C0ZNB1_RHOE4

ID   C0ZNB1_RHOE4            Unreviewed;       547 AA.
AC   C0ZNB1;
DT   26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   26-MAY-2009, sequence version 1.
DT   10-APR-2019, entry version 54.
DE   SubName: Full=Putative drug resistance efflux protein {ECO:0000313|EMBL:BAH31163.1};
GN   OrderedLocusNames=RER_04550 {ECO:0000313|EMBL:BAH31163.1};
OS   Rhodococcus erythropolis (strain PR4 / NBRC 100887).
OC   Bacteria; Actinobacteria; Corynebacteriales; Nocardiaceae;
OC   Rhodococcus.
OX   NCBI_TaxID=234621 {ECO:0000313|EMBL:BAH31163.1, ECO:0000313|Proteomes:UP000002204};
RN   [1] {ECO:0000313|Proteomes:UP000002204}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PR4 / NBRC 100887 {ECO:0000313|Proteomes:UP000002204};
RA   Takarada H., Sekine M., Hosoyama A., Yamada R., Fujisawa T., Omata S.,
RA   Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S.;
RT   "Comparison of the complete genome sequences of Rhodococcus
RT   erythropolis PR4 and Rhodococcus opacus B4.";
RL   Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:BAH31163.1, ECO:0000313|Proteomes:UP000002204}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PR4 / NBRC 100887 {ECO:0000313|Proteomes:UP000002204};
RX   PubMed=16423019; DOI=10.1111/j.1462-2920.2005.00899.x;
RA   Sekine M., Tanikawa S., Omata S., Saito M., Fujisawa T., Tsukatani N.,
RA   Tajima T., Sekigawa T., Kosugi H., Matsuo Y., Nishiko R., Imamura K.,
RA   Ito M., Narita H., Tago S., Fujita N., Harayama S.;
RT   "Sequence analysis of three plasmids harboured in Rhodococcus
RT   erythropolis strain PR4.";
RL   Environ. Microbiol. 8:334-346(2006).
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC       {ECO:0000256|SAAS:SAAS00769108}.
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DR   EMBL; AP008957; BAH31163.1; -; Genomic_DNA.
DR   STRING; 234621.RER_04550; -.
DR   EnsemblBacteria; BAH31163; BAH31163; RER_04550.
DR   KEGG; rer:RER_04550; -.
DR   eggNOG; ENOG4105C0R; Bacteria.
DR   eggNOG; ENOG410XNN3; LUCA.
DR   HOGENOM; HOG000239124; -.
DR   OMA; RWAFGIN; -.
DR   BioCyc; RERY234621:GHDE-464-MONOMER; -.
DR   Proteomes; UP000002204; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd06174; MFS; 1.
DR   InterPro; IPR004638; EmrB-like.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   TIGRFAMs; TIGR00711; efflux_EmrB; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
DR   PRODOM; C0ZNB1.
DR   SWISS-2DPAGE; C0ZNB1.
KW   Cell membrane {ECO:0000256|SAAS:SAAS00769078};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002204};
KW   Membrane {ECO:0000256|SAAS:SAAS00769060, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00769091,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00769070,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00769034}.
FT   TRANSMEM     20     44       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     64     81       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     88    107       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    113    134       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    146    168       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    174    196       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    208    226       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    246    270       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    301    321       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    327    349       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    361    381       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    387    413       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    510    529       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       22    534       MFS. {ECO:0000259|PROSITE:PS50850}.
SQ   SEQUENCE   547 AA;  56029 MW;  FA12C4DBBC4A2C6F CRC64;
     MKLLHNGGLF VNISPTTRKW LGLIAIALGV ALIVVDTTIV NVIVPSIIED LGINSVQAQW
     IQESYAIVFA ALLLLVGRVA DLVGARRIFI AGVVVFGATS LLAGLAPNGG LLILARFLQG
     AGAAMILPTS LSLLNAMFTG KARGQAFAVW GSTIGAASAL GPLLGGWLAE HASWRWAFGI
     NIPLAALILI GAVLFIAPSP RTAGRIDATG AALSIAGLGL LAFGLVEGRT YGWLTTKEPF
     DLFGLSWSSG PSPVLVALVL AVLSLGAFAY RQTMLTRSDD PSRALMDVRL FSISSFRNGN
     IATLIIGLGE FGIVAVLPLW LQFTLGYSAL QAGLALVPIA IGSFVASGAS FGMASKVSPL
     GLVRIGLALE ALGLAGLGFI AATDSPWWTI AAVLFFYGIG VGFATAQVTN VVLEEIPEQS
     AGQGSGIQSA FRQLGSALGI AVLTTVFFST LNSTLNNDLT ESGVDQAQAD QLTRAVTDSA
     GAAIDSLAGS PSTAFVADAA QSAMTHGITL GGYLAAGFVV VGLIATALIP NKPAPSTEEE
     TKAAADA
//

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