(data stored in ACNUC1104 zone)

SWISSPROT: C0ZSU7_RHOE4

ID   C0ZSU7_RHOE4            Unreviewed;       472 AA.
AC   C0ZSU7;
DT   26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   26-MAY-2009, sequence version 1.
DT   10-APR-2019, entry version 57.
DE   SubName: Full=Putative drug resistance efflux protein {ECO:0000313|EMBL:BAH31920.1};
GN   OrderedLocusNames=RER_12120 {ECO:0000313|EMBL:BAH31920.1};
OS   Rhodococcus erythropolis (strain PR4 / NBRC 100887).
OC   Bacteria; Actinobacteria; Corynebacteriales; Nocardiaceae;
OC   Rhodococcus.
OX   NCBI_TaxID=234621 {ECO:0000313|EMBL:BAH31920.1, ECO:0000313|Proteomes:UP000002204};
RN   [1] {ECO:0000313|Proteomes:UP000002204}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PR4 / NBRC 100887 {ECO:0000313|Proteomes:UP000002204};
RA   Takarada H., Sekine M., Hosoyama A., Yamada R., Fujisawa T., Omata S.,
RA   Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S.;
RT   "Comparison of the complete genome sequences of Rhodococcus
RT   erythropolis PR4 and Rhodococcus opacus B4.";
RL   Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:BAH31920.1, ECO:0000313|Proteomes:UP000002204}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PR4 / NBRC 100887 {ECO:0000313|Proteomes:UP000002204};
RX   PubMed=16423019; DOI=10.1111/j.1462-2920.2005.00899.x;
RA   Sekine M., Tanikawa S., Omata S., Saito M., Fujisawa T., Tsukatani N.,
RA   Tajima T., Sekigawa T., Kosugi H., Matsuo Y., Nishiko R., Imamura K.,
RA   Ito M., Narita H., Tago S., Fujita N., Harayama S.;
RT   "Sequence analysis of three plasmids harboured in Rhodococcus
RT   erythropolis strain PR4.";
RL   Environ. Microbiol. 8:334-346(2006).
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC       {ECO:0000256|SAAS:SAAS00769108}.
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DR   EMBL; AP008957; BAH31920.1; -; Genomic_DNA.
DR   STRING; 234621.RER_12120; -.
DR   EnsemblBacteria; BAH31920; BAH31920; RER_12120.
DR   KEGG; rer:RER_12120; -.
DR   eggNOG; ENOG4105C57; Bacteria.
DR   eggNOG; COG0477; LUCA.
DR   HOGENOM; HOG000239124; -.
DR   OMA; LWICASA; -.
DR   BioCyc; RERY234621:GHDE-1230-MONOMER; -.
DR   Proteomes; UP000002204; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd06174; MFS; 1.
DR   InterPro; IPR004638; EmrB-like.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR005829; Sugar_transporter_CS.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   TIGRFAMs; TIGR00711; efflux_EmrB; 1.
DR   PROSITE; PS50850; MFS; 1.
DR   PROSITE; PS00216; SUGAR_TRANSPORT_1; 1.
PE   3: Inferred from homology;
DR   PRODOM; C0ZSU7.
DR   SWISS-2DPAGE; C0ZSU7.
KW   Cell membrane {ECO:0000256|SAAS:SAAS00769078};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002204};
KW   Membrane {ECO:0000256|SAAS:SAAS00769060, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00769091,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00769070,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00769034}.
FT   TRANSMEM     25     45       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     65     84       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     96    120       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    126    143       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    155    178       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    184    203       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    215    233       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    239    260       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    281    305       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    317    339       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    346    365       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    377    397       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    418    435       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    447    466       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       27    471       MFS. {ECO:0000259|PROSITE:PS50850}.
SQ   SEQUENCE   472 AA;  48190 MW;  857F67293640F6FC CRC64;
     MESEMKPSSG IDEPQVIGLD ARRRWGILAI CCTSLFVVGL DTTIVNVALP AIGEGFGVGT
     VGLEWIVNAY TLVLASLLIS SGALADRFGR RRIFQIGLVV FGVASIVCAL APSVGVLIAA
     RIAQGVGGSM LSPVALAIVV NVMTDPKERA KAIGVWAAVF GLSMAAGPIV GGVLIESFGW
     RSVFWINVPV IAVVLMLTAV FVPQSRAEQP RRLDLPGQVL LMVVVGGSVA LLIEGPRIGW
     LASGAIAGYV AVAAALAAFV RVESRKSEPL MDPSLFRHRP FTAAVLGAIV VFVALNATLL
     LGTFYLQQAR EMTPAAAGAM TLPMAVAATI CAPLSGILVG RFGARLPLLI AGSFTALGGL
     CLVSLDNSTG TSTLLVAYLF LGIGFGFSNA PITNTAVNGL PRSQAGLAGG ITSSARQFGA
     ALGVALAGGM IAGSAQSDID EASRAGWILV VACGLVVLVI ALASGGSEKT KG
//

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