(data stored in SCRATCH zone)

SWISSPROT: C1AS81_RHOOB

ID   C1AS81_RHOOB            Unreviewed;       581 AA.
AC   C1AS81;
DT   26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   26-MAY-2009, sequence version 1.
DT   05-JUL-2017, entry version 59.
DE   RecName: Full=Cytochrome c oxidase subunit 1 {ECO:0000256|RuleBase:RU363061};
DE            EC=1.9.3.1 {ECO:0000256|RuleBase:RU363061};
GN   Name=ctaD {ECO:0000313|EMBL:BAH48330.1};
GN   OrderedLocusNames=ROP_00830 {ECO:0000313|EMBL:BAH48330.1};
OS   Rhodococcus opacus (strain B4).
OC   Bacteria; Actinobacteria; Corynebacteriales; Nocardiaceae;
OC   Rhodococcus.
OX   NCBI_TaxID=632772 {ECO:0000313|EMBL:BAH48330.1, ECO:0000313|Proteomes:UP000002212};
RN   [1] {ECO:0000313|EMBL:BAH48330.1, ECO:0000313|Proteomes:UP000002212}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=B4 {ECO:0000313|EMBL:BAH48330.1,
RC   ECO:0000313|Proteomes:UP000002212};
RA   Takarada H., Sekine M., Hosoyama A., Yamada R., Fujisawa T., Omata S.,
RA   Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S.;
RT   "Comparison of the complete genome sequences of Rhodococcus
RT   erythropolis PR4 and Rhodococcus opacus B4.";
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Cytochrome c oxidase is the component of the respiratory
CC       chain that catalyzes the reduction of oxygen to water. Subunits 1-
CC       3 form the functional core of the enzyme complex. CO I is the
CC       catalytic subunit of the enzyme. Electrons originating in
CC       cytochrome c are transferred via the copper A center of subunit 2
CC       and heme A of subunit 1 to the bimetallic center formed by heme A3
CC       and copper B. {ECO:0000256|RuleBase:RU363061}.
CC   -!- CATALYTIC ACTIVITY: 4 ferrocytochrome c + O(2) + 4 H(+) = 4
CC       ferricytochrome c + 2 H(2)O. {ECO:0000256|RuleBase:RU363061}.
CC   -!- PATHWAY: Energy metabolism; oxidative phosphorylation.
CC       {ECO:0000256|RuleBase:RU363061}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane
CC       {ECO:0000256|RuleBase:RU363061}; Multi-pass membrane protein
CC       {ECO:0000256|RuleBase:RU363061}.
CC   -!- SIMILARITY: Belongs to the heme-copper respiratory oxidase family.
CC       {ECO:0000256|RuleBase:RU363061}.
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DR   EMBL; AP011115; BAH48330.1; -; Genomic_DNA.
DR   RefSeq; WP_012687340.1; NC_012522.1.
DR   STRING; 632772.ROP_00830; -.
DR   EnsemblBacteria; BAH48330; BAH48330; ROP_00830.
DR   KEGG; rop:ROP_00830; -.
DR   PATRIC; fig|632772.20.peg.104; -.
DR   eggNOG; ENOG4105BZ9; Bacteria.
DR   eggNOG; COG0843; LUCA.
DR   HOGENOM; HOG000085274; -.
DR   KO; K02274; -.
DR   OMA; GIVMVWF; -.
DR   OrthoDB; POG091H042R; -.
DR   UniPathway; UPA00705; -.
DR   Proteomes; UP000002212; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0070469; C:respiratory chain; IEA:UniProtKB-KW.
DR   GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0009060; P:aerobic respiration; IEA:InterPro.
DR   GO; GO:0022900; P:electron transport chain; IEA:InterPro.
DR   GO; GO:0006119; P:oxidative phosphorylation; IEA:UniProtKB-UniPathway.
DR   Gene3D; 1.20.210.10; -; 1.
DR   InterPro; IPR023616; Cyt_c_oxase-like_su1_dom.
DR   InterPro; IPR000883; Cyt_C_Oxase_1.
DR   InterPro; IPR023615; Cyt_c_Oxase_su1_BS.
DR   InterPro; IPR014241; Cyt_c_oxidase_su1_bac.
DR   PANTHER; PTHR10422; PTHR10422; 1.
DR   Pfam; PF00115; COX1; 1.
DR   PRINTS; PR01165; CYCOXIDASEI.
DR   SUPFAM; SSF81442; SSF81442; 1.
DR   TIGRFAMs; TIGR02891; CtaD_CoxA; 1.
DR   PROSITE; PS50855; COX1; 1.
DR   PROSITE; PS00077; COX1_CUB; 1.
PE   3: Inferred from homology;
DR   PRODOM; C1AS81.
DR   SWISS-2DPAGE; C1AS81.
KW   Cell membrane {ECO:0000256|RuleBase:RU363061};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002212};
KW   Copper {ECO:0000256|RuleBase:RU363061};
KW   Electron transport {ECO:0000256|RuleBase:RU363061};
KW   Heme {ECO:0000256|RuleBase:RU363061};
KW   Iron {ECO:0000256|RuleBase:RU363061};
KW   Membrane {ECO:0000256|RuleBase:RU363061};
KW   Metal-binding {ECO:0000256|RuleBase:RU363061};
KW   Oxidoreductase {ECO:0000256|RuleBase:RU363061,
KW   ECO:0000313|EMBL:BAH48330.1};
KW   Respiratory chain {ECO:0000256|RuleBase:RU363061};
KW   Transmembrane {ECO:0000256|RuleBase:RU363061};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU363061};
KW   Transport {ECO:0000256|RuleBase:RU363061}.
FT   TRANSMEM     39     59       Helical. {ECO:0000256|RuleBase:RU363061}.
FT   TRANSMEM     79    104       Helical. {ECO:0000256|RuleBase:RU363061}.
FT   TRANSMEM    124    148       Helical. {ECO:0000256|RuleBase:RU363061}.
FT   TRANSMEM    168    193       Helical. {ECO:0000256|RuleBase:RU363061}.
FT   TRANSMEM    205    231       Helical. {ECO:0000256|RuleBase:RU363061}.
FT   TRANSMEM    251    275       Helical. {ECO:0000256|RuleBase:RU363061}.
FT   TRANSMEM    287    308       Helical. {ECO:0000256|RuleBase:RU363061}.
FT   TRANSMEM    314    336       Helical. {ECO:0000256|RuleBase:RU363061}.
FT   TRANSMEM    357    377       Helical. {ECO:0000256|RuleBase:RU363061}.
FT   TRANSMEM    389    415       Helical. {ECO:0000256|RuleBase:RU363061}.
FT   TRANSMEM    427    449       Helical. {ECO:0000256|RuleBase:RU363061}.
FT   TRANSMEM    469    490       Helical. {ECO:0000256|RuleBase:RU363061}.
FT   DOMAIN       20    534       COX1. {ECO:0000259|PROSITE:PS50855}.
SQ   SEQUENCE   581 AA;  64582 MW;  EBB697F727F741EE CRC64;
     MTPLTVEVVP VRPFPARRGI KGSFLYKAAT TTDPKMLGLM YMVTSFVFFM VGGLMALLIR
     TELAVPGLQF LSNEQYNQLF TMHGTIMLLL YATPIVFGFA NYILPLQIGA PDVAFPRLNA
     LSYWLYLFGA IITVSGFLTP GGAADFGWTG YSPLTSAVHS PGVGADVWIT GLALAGVGTI
     LGGVNMITTV ICLRAPGMTM FRMPIFTWNI FITMILVLIA FPILAAALLG LLVDRHLGAH
     LFDPATGGAL LWQHLFWFFG HPEVYIVAIP FFGIVSEIFP VFSRKPLFGY TGLVYATIAI
     AALSTAVWAH HMFATGAVLL PFFSLMSFFI AVPTGVKFFN WIGTMWKGQL TFETPMLFSI
     GFLVTFLFGG LSGVLLASPP LDFHVTDSYF LVAHFHYVLF GTIVFATYAG IYFWFPKMTG
     RLMDERLGRW HFWTTFIGFH TTFLVQHWLG AEGMPRRYAD YLPSDGFTTL NTVSTIGSFV
     LGGSVLPFVW NVFKSYRYGQ VVTVDDPWGY GNSLEWATSC PPPRHNFTEL PRIRSERPAF
     ELHYPHMVKR MRAETYVGRR PKSVAVTAGT VSGPEREAGR R
//

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