(data stored in SCRATCH zone)

SWISSPROT: C1E1A5_MICCC

ID   C1E1A5_MICCC            Unreviewed;       263 AA.
AC   C1E1A5;
DT   26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   26-MAY-2009, sequence version 1.
DT   08-MAY-2019, entry version 45.
DE   RecName: Full=Proliferating cell nuclear antigen {ECO:0000256|RuleBase:RU000641};
GN   ORFNames=MICPUN_93665 {ECO:0000313|EMBL:ACO62137.1};
OS   Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709) (Picoplanktonic
OS   green alga).
OC   Eukaryota; Viridiplantae; Chlorophyta; Mamiellophyceae; Mamiellales;
OC   Mamiellaceae; Micromonas.
OX   NCBI_TaxID=296587 {ECO:0000313|EMBL:ACO62137.1, ECO:0000313|Proteomes:UP000002009};
RN   [1] {ECO:0000313|EMBL:ACO62137.1, ECO:0000313|Proteomes:UP000002009}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RCC299 / NOUM17 {ECO:0000313|Proteomes:UP000002009};
RX   PubMed=19359590; DOI=10.1126/science.1167222;
RA   Worden A.Z., Lee J.H., Mock T., Rouze P., Simmons M.P., Aerts A.L.,
RA   Allen A.E., Cuvelier M.L., Derelle E., Everett M.V., Foulon E.,
RA   Grimwood J., Gundlach H., Henrissat B., Napoli C., McDonald S.M.,
RA   Parker M.S., Rombauts S., Salamov A., Von Dassow P., Badger J.H.,
RA   Coutinho P.M., Demir E., Dubchak I., Gentemann C., Eikrem W.,
RA   Gready J.E., John U., Lanier W., Lindquist E.A., Lucas S., Mayer K.F.,
RA   Moreau H., Not F., Otillar R., Panaud O., Pangilinan J., Paulsen I.,
RA   Piegu B., Poliakov A., Robbens S., Schmutz J., Toulza E., Wyss T.,
RA   Zelensky A., Zhou K., Armbrust E.V., Bhattacharya D., Goodenough U.W.,
RA   Van de Peer Y., Grigoriev I.V.;
RT   "Green evolution and dynamic adaptations revealed by genomes of the
RT   marine picoeukaryotes Micromonas.";
RL   Science 324:268-272(2009).
CC   -!- FUNCTION: This protein is an auxiliary protein of DNA polymerase
CC       delta and is involved in the control of eukaryotic DNA replication
CC       by increasing the polymerase's processibility during elongation of
CC       the leading strand. {ECO:0000256|RuleBase:RU000641}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU000641}.
CC   -!- SIMILARITY: Belongs to the PCNA family.
CC       {ECO:0000256|RuleBase:RU003671}.
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DR   EMBL; CP001324; ACO62137.1; -; Genomic_DNA.
DR   RefSeq; XP_002500879.1; XM_002500833.1.
DR   STRING; 296587.XP_002500879.1; -.
DR   GeneID; 8241637; -.
DR   KEGG; mis:MICPUN_93665; -.
DR   HOGENOM; HOG000211098; -.
DR   InParanoid; C1E1A5; -.
DR   KO; K04802; -.
DR   OMA; KILRCAG; -.
DR   OrthoDB; 1012066at2759; -.
DR   Proteomes; UP000002009; Chromosome 3.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030337; F:DNA polymerase processivity factor activity; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   HAMAP; MF_00317; DNApol_clamp_arch; 1.
DR   InterPro; IPR000730; Pr_cel_nuc_antig.
DR   InterPro; IPR022649; Pr_cel_nuc_antig_C.
DR   InterPro; IPR022659; Pr_cel_nuc_antig_CS.
DR   InterPro; IPR022648; Pr_cel_nuc_antig_N.
DR   Pfam; PF02747; PCNA_C; 1.
DR   Pfam; PF00705; PCNA_N; 1.
DR   PRINTS; PR00339; PCNACYCLIN.
DR   TIGRFAMs; TIGR00590; pcna; 1.
DR   PROSITE; PS01251; PCNA_1; 1.
DR   PROSITE; PS00293; PCNA_2; 1.
PE   3: Inferred from homology;
DR   PRODOM; C1E1A5.
DR   SWISS-2DPAGE; C1E1A5.
KW   Complete proteome {ECO:0000313|Proteomes:UP000002009};
KW   DNA replication {ECO:0000256|RuleBase:RU003671};
KW   DNA-binding {ECO:0000256|RuleBase:RU003671};
KW   Nucleus {ECO:0000256|RuleBase:RU000641};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002009}.
FT   DOMAIN        1    124       PCNA_N. {ECO:0000259|Pfam:PF00705}.
FT   DOMAIN      127    253       PCNA_C. {ECO:0000259|Pfam:PF02747}.
SQ   SEQUENCE   263 AA;  29240 MW;  47977B5247C31333 CRC64;
     MFEARLVQGS LLKKVLESIK DLVTDANFDC SNNGFALQAM DSSHVSLVAL LLRSDGFEHY
     RCDRNMTMGM NLSNMSKMLK CAGNEDIITM KADDTGDVVT FMFESPDQDK ISDFELKLMD
     IDSEHLGIPD TEYAATVKMP SSEFMRICRD LSSIGDTVTI SVSKDGVKFS TTGDIGQANI
     TCRQNTSVDK EEQTIIELQE PVTLTFALRY LNSFTKATPL APTVQLQMSK ELPVVVQYLI
     ADMGYVRYYL APKIEDDETA EAA
//

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