(data stored in SCRATCH zone)

SWISSPROT: C3MEZ8_SINFN

ID   C3MEZ8_SINFN            Unreviewed;       933 AA.
AC   C3MEZ8;
DT   16-JUN-2009, integrated into UniProtKB/TrEMBL.
DT   16-JUN-2009, sequence version 1.
DT   05-JUL-2017, entry version 66.
DE   RecName: Full=DNA mismatch repair protein MutS {ECO:0000256|HAMAP-Rule:MF_00096, ECO:0000256|SAAS:SAAS00825254};
GN   Name=mutS {ECO:0000256|HAMAP-Rule:MF_00096,
GN   ECO:0000313|EMBL:ACP23835.1};
GN   OrderedLocusNames=NGR_c00310 {ECO:0000313|EMBL:ACP23835.1};
OS   Sinorhizobium fredii (strain NBRC 101917 / NGR234).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=394 {ECO:0000313|EMBL:ACP23835.1, ECO:0000313|Proteomes:UP000001054};
RN   [1] {ECO:0000313|EMBL:ACP23835.1, ECO:0000313|Proteomes:UP000001054}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 101917 / NGR234 {ECO:0000313|Proteomes:UP000001054};
RX   PubMed=19376903; DOI=10.1128/AEM.00515-09;
RA   Schmeisser C., Liesegang H., Krysciak D., Bakkou N., Le Quere A.,
RA   Wollherr A., Heinemeyer I., Morgenstern B., Pommerening-Roeser A.,
RA   Flores M., Palacios R., Brenner S., Gottschalk G., Schmitz R.A.,
RA   Broughton W.J., Perret X., Strittmatter A.W., Streit W.R.;
RT   "Rhizobium sp. strain NGR234 possesses a remarkable number of
RT   secretion systems.";
RL   Appl. Environ. Microbiol. 75:4035-4045(2009).
CC   -!- FUNCTION: This protein is involved in the repair of mismatches in
CC       DNA. It is possible that it carries out the mismatch recognition
CC       step. This protein has a weak ATPase activity. {ECO:0000256|HAMAP-
CC       Rule:MF_00096, ECO:0000256|SAAS:SAAS00825242}.
CC   -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family.
CC       {ECO:0000256|HAMAP-Rule:MF_00096, ECO:0000256|RuleBase:RU003756,
CC       ECO:0000256|SAAS:SAAS00639499}.
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DR   EMBL; CP001389; ACP23835.1; -; Genomic_DNA.
DR   RefSeq; WP_012706620.1; NC_012587.1.
DR   RefSeq; YP_002824588.1; NC_012587.1.
DR   STRING; 394.NGR_c00310; -.
DR   EnsemblBacteria; ACP23835; ACP23835; NGR_c00310.
DR   GeneID; 7790610; -.
DR   KEGG; rhi:NGR_c00310; -.
DR   PATRIC; fig|394.7.peg.2821; -.
DR   eggNOG; ENOG4105D86; Bacteria.
DR   eggNOG; COG0249; LUCA.
DR   HOGENOM; HOG000221407; -.
DR   KO; K03555; -.
DR   OMA; TPMMAQY; -.
DR   OrthoDB; POG091H0293; -.
DR   Proteomes; UP000001054; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003684; F:damaged DNA binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR   GO; GO:0006298; P:mismatch repair; IEA:UniProtKB-HAMAP.
DR   Gene3D; 3.30.420.110; -; 1.
DR   Gene3D; 3.40.1170.10; -; 1.
DR   HAMAP; MF_00096; MutS; 1.
DR   InterPro; IPR005748; DNA_mismatch_repair_MutS.
DR   InterPro; IPR007695; DNA_mismatch_repair_MutS-lik_N.
DR   InterPro; IPR017261; DNA_mismatch_repair_MutS/MSH.
DR   InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR   InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR   InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR   InterPro; IPR016151; DNA_mismatch_repair_MutS_N.
DR   InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF01624; MutS_I; 1.
DR   Pfam; PF05188; MutS_II; 1.
DR   Pfam; PF05192; MutS_III; 1.
DR   Pfam; PF05190; MutS_IV; 1.
DR   Pfam; PF00488; MutS_V; 1.
DR   PIRSF; PIRSF037677; DNA_mis_repair_Msh6; 1.
DR   SMART; SM00534; MUTSac; 1.
DR   SMART; SM00533; MUTSd; 1.
DR   SUPFAM; SSF48334; SSF48334; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   SUPFAM; SSF53150; SSF53150; 1.
DR   SUPFAM; SSF55271; SSF55271; 1.
DR   TIGRFAMs; TIGR01070; mutS1; 1.
DR   PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE   3: Inferred from homology;
DR   PRODOM; C3MEZ8.
DR   SWISS-2DPAGE; C3MEZ8.
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00096,
KW   ECO:0000256|SAAS:SAAS00639492}; Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001054};
KW   DNA damage {ECO:0000256|HAMAP-Rule:MF_00096,
KW   ECO:0000256|RuleBase:RU003756, ECO:0000256|SAAS:SAAS00639525};
KW   DNA repair {ECO:0000256|HAMAP-Rule:MF_00096,
KW   ECO:0000256|RuleBase:RU003756, ECO:0000256|SAAS:SAAS00680424};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00096,
KW   ECO:0000256|RuleBase:RU003756, ECO:0000256|SAAS:SAAS00639511};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00096,
KW   ECO:0000256|RuleBase:RU003756, ECO:0000256|SAAS:SAAS00639465};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001054}.
FT   DOMAIN      757    773       DNA_MISMATCH_REPAIR_2.
FT                                {ECO:0000259|PROSITE:PS00486}.
FT   NP_BIND     683    690       ATP. {ECO:0000256|HAMAP-Rule:MF_00096}.
FT   COILED      559    586       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   933 AA;  100873 MW;  F7D49116F857D705 CRC64;
     MSSINACGYC DISFFGTIMN FVSDASSRTG DVLSVSDLAS EESRSTATPM MEQFIEIKAN
     NPDSLLFYRM GDFYELFFQD AVEASRALGI TLTKRGQHLG QDIPMCGVPV HAADDYLQKL
     IALGFRVAVC EQVEDPAEAK KRGSKSVVRR DVVRLVTPGT ITEDKLLSPS ESNYLMALAR
     IRSGSEPAYA LAWIDISTGI FRLAETAESR LLADILRVEP RELILPDTVF HDPELRPVFD
     VLGRVAVPQP AVLFDSATAE GRIARYYGVK TLDGFGTFSR AELAAASAAI SYVEKTQIQE
     RPALGIPERE SAASTLFIDP ATRANLELVK TLSGAREGTL LRALDRTVTS GGARLLAERL
     MSPLTDPDRI NQRLDSIEVL LDQPSFAIDV RDTLRRAPDM PRALSRLALG RGGPRDLGAI
     QAGLRAAAAT ATLLSGARLS EELTEAHAAI AALPAALLAR LDSMLAEDLP LLKRDGGFLR
     EAASGELDEM RALRDQSRRV IAGLQLQYCE ETGIKSLKIK HNNVLGYFIE VTAGNAGAMT
     DTDAGRARFI HRQTMASAMR FTTTELAELE TKIANAADRA LAIELEAFEA MAREVVADAE
     AIKAASLALA MLDVSAGLAV LAEEQNYARP AVDRSRMFLI DGGRHPVVEQ ALRRQAGNPF
     VANGCDLSPP DGPEAGAIWL LTGPNMGGKS TFLRQNALIA IMAQMGSFVP ANAAHIGIVD
     RLFSRVGASD DLARGRSTFM VEMVETAAIL NQATDHSLVI LDEIGRGTAT FDGLSIAWAA
     VEHLHEVNRC RGLFATHFHE LTVLSEKLGR LSNATMRVKE WDGDVIFLHE VGPGAADRSY
     GIQVARLAGL PASVVARARD VLANLEDADR KNPASQLIDD LPLFQVAVRR EEVARASGPS
     RAEEALRAIN PDDMTPREAL EALYALKKDL AGR
//

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