(data stored in SCRATCH zone)

SWISSPROT: C3MHJ2_SINFN

ID   C3MHJ2_SINFN            Unreviewed;       563 AA.
AC   C3MHJ2;
DT   16-JUN-2009, integrated into UniProtKB/TrEMBL.
DT   16-JUN-2009, sequence version 1.
DT   05-JUL-2017, entry version 61.
DE   RecName: Full=Cytochrome c oxidase subunit 1 {ECO:0000256|RuleBase:RU363061};
DE            EC=1.9.3.1 {ECO:0000256|RuleBase:RU363061};
GN   Name=ctaD {ECO:0000313|EMBL:ACP24320.1};
GN   OrderedLocusNames=NGR_c05240 {ECO:0000313|EMBL:ACP24320.1};
OS   Sinorhizobium fredii (strain NBRC 101917 / NGR234).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=394 {ECO:0000313|EMBL:ACP24320.1, ECO:0000313|Proteomes:UP000001054};
RN   [1] {ECO:0000313|EMBL:ACP24320.1, ECO:0000313|Proteomes:UP000001054}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 101917 / NGR234 {ECO:0000313|Proteomes:UP000001054};
RX   PubMed=19376903; DOI=10.1128/AEM.00515-09;
RA   Schmeisser C., Liesegang H., Krysciak D., Bakkou N., Le Quere A.,
RA   Wollherr A., Heinemeyer I., Morgenstern B., Pommerening-Roeser A.,
RA   Flores M., Palacios R., Brenner S., Gottschalk G., Schmitz R.A.,
RA   Broughton W.J., Perret X., Strittmatter A.W., Streit W.R.;
RT   "Rhizobium sp. strain NGR234 possesses a remarkable number of
RT   secretion systems.";
RL   Appl. Environ. Microbiol. 75:4035-4045(2009).
CC   -!- FUNCTION: Cytochrome c oxidase is the component of the respiratory
CC       chain that catalyzes the reduction of oxygen to water. Subunits 1-
CC       3 form the functional core of the enzyme complex. CO I is the
CC       catalytic subunit of the enzyme. Electrons originating in
CC       cytochrome c are transferred via the copper A center of subunit 2
CC       and heme A of subunit 1 to the bimetallic center formed by heme A3
CC       and copper B. {ECO:0000256|RuleBase:RU363061}.
CC   -!- CATALYTIC ACTIVITY: 4 ferrocytochrome c + O(2) + 4 H(+) = 4
CC       ferricytochrome c + 2 H(2)O. {ECO:0000256|RuleBase:RU363061}.
CC   -!- PATHWAY: Energy metabolism; oxidative phosphorylation.
CC       {ECO:0000256|RuleBase:RU363061}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane
CC       {ECO:0000256|RuleBase:RU363061}; Multi-pass membrane protein
CC       {ECO:0000256|RuleBase:RU363061}.
CC   -!- SIMILARITY: Belongs to the heme-copper respiratory oxidase family.
CC       {ECO:0000256|RuleBase:RU363061}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CP001389; ACP24320.1; -; Genomic_DNA.
DR   RefSeq; WP_012707105.1; NC_012587.1.
DR   RefSeq; YP_002825073.1; NC_012587.1.
DR   STRING; 394.NGR_c05240; -.
DR   EnsemblBacteria; ACP24320; ACP24320; NGR_c05240.
DR   GeneID; 7791750; -.
DR   KEGG; rhi:NGR_c05240; -.
DR   PATRIC; fig|394.7.peg.3337; -.
DR   eggNOG; ENOG4105BZ9; Bacteria.
DR   eggNOG; COG0843; LUCA.
DR   HOGENOM; HOG000085274; -.
DR   KO; K02274; -.
DR   OMA; FTVGMGP; -.
DR   OrthoDB; POG091H042R; -.
DR   UniPathway; UPA00705; -.
DR   Proteomes; UP000001054; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0045277; C:respiratory chain complex IV; IEA:InterPro.
DR   GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0009060; P:aerobic respiration; IEA:InterPro.
DR   GO; GO:0022900; P:electron transport chain; IEA:InterPro.
DR   GO; GO:0006119; P:oxidative phosphorylation; IEA:UniProtKB-UniPathway.
DR   CDD; cd01663; Cyt_c_Oxidase_I; 1.
DR   Gene3D; 1.20.210.10; -; 1.
DR   InterPro; IPR023616; Cyt_c_oxase-like_su1_dom.
DR   InterPro; IPR000883; Cyt_C_Oxase_1.
DR   InterPro; IPR023615; Cyt_c_Oxase_su1_BS.
DR   InterPro; IPR033944; Cyt_c_oxase_su1_dom.
DR   InterPro; IPR014241; Cyt_c_oxidase_su1_bac.
DR   PANTHER; PTHR10422; PTHR10422; 1.
DR   Pfam; PF00115; COX1; 1.
DR   PRINTS; PR01165; CYCOXIDASEI.
DR   SUPFAM; SSF81442; SSF81442; 1.
DR   TIGRFAMs; TIGR02891; CtaD_CoxA; 1.
DR   PROSITE; PS50855; COX1; 1.
DR   PROSITE; PS00077; COX1_CUB; 1.
PE   3: Inferred from homology;
DR   PRODOM; C3MHJ2.
DR   SWISS-2DPAGE; C3MHJ2.
KW   Cell membrane {ECO:0000256|RuleBase:RU363061};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001054};
KW   Copper {ECO:0000256|RuleBase:RU363061};
KW   Electron transport {ECO:0000256|RuleBase:RU363061};
KW   Heme {ECO:0000256|RuleBase:RU363061};
KW   Iron {ECO:0000256|RuleBase:RU363061};
KW   Membrane {ECO:0000256|RuleBase:RU363061};
KW   Metal-binding {ECO:0000256|RuleBase:RU363061};
KW   Oxidoreductase {ECO:0000256|RuleBase:RU363061};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001054};
KW   Respiratory chain {ECO:0000256|RuleBase:RU363061};
KW   Transmembrane {ECO:0000256|RuleBase:RU363061};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU363061};
KW   Transport {ECO:0000256|RuleBase:RU363061}.
FT   TRANSMEM     43     65       Helical. {ECO:0000256|RuleBase:RU363061}.
FT   TRANSMEM    108    134       Helical. {ECO:0000256|RuleBase:RU363061}.
FT   TRANSMEM    146    164       Helical. {ECO:0000256|RuleBase:RU363061}.
FT   TRANSMEM    195    221       Helical. {ECO:0000256|RuleBase:RU363061}.
FT   TRANSMEM    233    260       Helical. {ECO:0000256|RuleBase:RU363061}.
FT   TRANSMEM    280    304       Helical. {ECO:0000256|RuleBase:RU363061}.
FT   TRANSMEM    316    338       Helical. {ECO:0000256|RuleBase:RU363061}.
FT   TRANSMEM    353    375       Helical. {ECO:0000256|RuleBase:RU363061}.
FT   TRANSMEM    387    408       Helical. {ECO:0000256|RuleBase:RU363061}.
FT   TRANSMEM    420    443       Helical. {ECO:0000256|RuleBase:RU363061}.
FT   TRANSMEM    463    485       Helical. {ECO:0000256|RuleBase:RU363061}.
FT   TRANSMEM    505    526       Helical. {ECO:0000256|RuleBase:RU363061}.
FT   DOMAIN       34    563       COX1. {ECO:0000259|PROSITE:PS50855}.
SQ   SEQUENCE   563 AA;  62224 MW;  2DD550CD12D1ECB5 CRC64;
     MAGTAVHHDH RHDHSDHAHD ADHAHKPLTF FQRWFLSTNH KDIGTLYLIF GIIAGLIGGT
     LSVFMRAELQ EPGIQIFHGL AQMVYGFEGD AAIDGGKHMF NVFTTAHALI MIFFMVMPAL
     IGGFANWMVP IMIGAPDMAF PRMNNISFWL IVPAFLLVLL SMFVEGPAGA YGAGGGWTIY
     PPFSTSGMPG PAMDLAILGL HIAGASSILG AINFITTILN MRAPGMTLHK MPLFAWSVLI
     TAFLLLLSLP VLAGAITMLL TDRNFGTTFF APEGGGDPIL FQHLFWFFGH PEVYILILPG
     FGIVSHIIST FSRKPIFGYL GMAYAMVAIG AVGFIVWAHH MYTVGMSLET QRYFVFATMV
     IAVPTGVKIF SWIATMWGGS IRFTTPMVWA IGFIFLFTVG GVTGVQLANA GLDRALHDTY
     YVVAHFHYVL SLGAVFAIFA AWYYWFPKMS GYMYSEFLGK LHFWVMFVGV NLIFFPQHFL
     GLAGMPRRYI DYPDAFAGWN MVSSYGSYIA AVGVLIFLFG VAEAFAKKRV AGDNPWGEGA
     NTLEWQLSSP PPFHQWEQLP RIK
//

If you have problems or comments...

PBIL Back to PBIL home page