(data stored in SCRATCH zone)

SWISSPROT: C4IYR0_MAIZE

ID   C4IYR0_MAIZE            Unreviewed;       447 AA.
AC   C4IYR0;
DT   07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   07-JUL-2009, sequence version 1.
DT   11-DEC-2019, entry version 87.
DE   RecName: Full=Non-specific serine/threonine protein kinase {ECO:0000256|SAAS:SAAS01217173};
DE            EC=2.7.11.1 {ECO:0000256|SAAS:SAAS01217173};
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577 {ECO:0000313|EMBL:ACR34060.1};
RN   [1] {ECO:0000313|EMBL:ACR34060.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=B73 {ECO:0000313|EMBL:ACR34060.1};
RX   PubMed=19936069; DOI=10.1371/journal.pgen.1000740;
RA   Soderlund C., Descour A., Kudrna D., Bomhoff M., Boyd L., Currie J.,
RA   Angelova A., Collura K., Wissotski M., Ashley E., Morrow D., Fernandes J.,
RA   Walbot V., Yu Y.;
RT   "Sequencing, mapping, and analysis of 27,455 maize full-length cDNAs.";
RL   PLoS Genet. 5:E1000740-E1000740(2009).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC         [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC         COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC         Evidence={ECO:0000256|SAAS:SAAS01217164};
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC         threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC         Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC         EC=2.7.11.1; Evidence={ECO:0000256|SAAS:SAAS01217170};
CC   -!- SIMILARITY: Belongs to the protein kinase superfamily.
CC       {ECO:0000256|RuleBase:RU000304}.
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DR   EMBL; BT083707; ACR34060.1; -; mRNA.
DR   RefSeq; NP_001170561.1; NM_001177090.1.
DR   RefSeq; XP_008662258.1; XM_008664036.1.
DR   PaxDb; C4IYR0; -.
DR   GeneID; 100384585; -.
DR   KEGG; zma:100384585; -.
DR   eggNOG; KOG0583; Eukaryota.
DR   eggNOG; COG0515; LUCA.
DR   HOGENOM; HOG000233016; -.
DR   OrthoDB; 1127668at2759; -.
DR   ExpressionAtlas; C4IYR0; baseline and differential.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR018451; NAF/FISL_domain.
DR   InterPro; IPR004041; NAF_dom.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR017441; Protein_kinase_ATP_BS.
DR   InterPro; IPR008271; Ser/Thr_kinase_AS.
DR   Pfam; PF03822; NAF; 1.
DR   Pfam; PF00069; Pkinase; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF56112; SSF56112; 1.
DR   PROSITE; PS50816; NAF; 1.
DR   PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE   2: Evidence at transcript level;
DR   PRODOM; C4IYR0.
DR   SWISS-2DPAGE; C4IYR0.
KW   ATP-binding {ECO:0000256|RuleBase:RU000304, ECO:0000256|SAAS:SAAS01217168};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Kinase {ECO:0000256|SAAS:SAAS01217163};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU000304,
KW   ECO:0000256|SAAS:SAAS01217174};
KW   Serine/threonine-protein kinase {ECO:0000256|RuleBase:RU000304,
KW   ECO:0000256|SAAS:SAAS01217167};
KW   Transferase {ECO:0000256|SAAS:SAAS01217169}.
FT   DOMAIN          17..272
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
FT   DOMAIN          314..338
FT                   /note="NAF"
FT                   /evidence="ECO:0000259|PROSITE:PS50816"
FT   COILED          357..377
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   447 AA;  50721 MW;  BB9AC1E26E9B1A3A CRC64;
     MEIKDMKTRG KTLTERYEMG KLLGKGAFGK VHYARDLESN QGVAIKIMDK DRVLKAGLSE
     QVKREITTMR LVEHKNIVRL HEVMATRNKI YIIMEYAKGG ELLDKVKRSG RLTEADTHRY
     FQQLIGALDH CHSRGVYHRD LKRENLLLDE NGDLKVSDFG LSAFSESRRT DGLLHTVCGT
     PVYIAPEVIK KTGYDGAKSD IWSCGVVLFV LAAGYLPFQG PNMMEIYRKI HDSDFRCPSW
     FSHKLKRLLY KILNPNPSMR PSIQEIKEST WFRKGPREIS AVKEKVLSEN ATATNAAPVL
     AARRKEIAHE DKTLVATKLN AFEIIAFSAG LDLSGLFIKE CRKETRFTSD KPALAIISKL
     EDVAKALNLR IRKKDNNTVI IQGRKHGGNG VLQFDTQIFE ITPSCHLVQM KQTSGDLLEY
     QKLLEEGIRP GLKDVVWAWH GDDLQQK
//

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