(data stored in SCRATCH zone)

SWISSPROT: C4KDP7_SULIK

ID   C4KDP7_SULIK            Unreviewed;       205 AA.
AC   C4KDP7;
DT   07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   07-JUL-2009, sequence version 1.
DT   07-JUN-2017, entry version 35.
DE   RecName: Full=Probable thymidylate kinase {ECO:0000256|HAMAP-Rule:MF_00165};
DE            EC=2.7.4.9 {ECO:0000256|HAMAP-Rule:MF_00165};
DE   AltName: Full=dTMP kinase {ECO:0000256|HAMAP-Rule:MF_00165};
GN   Name=tmk {ECO:0000256|HAMAP-Rule:MF_00165};
GN   OrderedLocusNames=M164_0390 {ECO:0000313|EMBL:ACR41020.1};
OS   Sulfolobus islandicus (strain M.16.4 / Kamchatka #3).
OC   Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Sulfolobus.
OX   NCBI_TaxID=426118 {ECO:0000313|EMBL:ACR41020.1, ECO:0000313|Proteomes:UP000001479};
RN   [1] {ECO:0000313|EMBL:ACR41020.1, ECO:0000313|Proteomes:UP000001479}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=M.16.4 / Kamchatka #3 {ECO:0000313|Proteomes:UP000001479};
RX   PubMed=19435847; DOI=10.1073/pnas.0808945106;
RA   Reno M.L., Held N.L., Fields C.J., Burke P.V., Whitaker R.J.;
RT   "Biogeography of the Sulfolobus islandicus pan-genome.";
RL   Proc. Natl. Acad. Sci. U.S.A. 106:8605-8610(2009).
CC   -!- CATALYTIC ACTIVITY: ATP + dTMP = ADP + dTDP. {ECO:0000256|HAMAP-
CC       Rule:MF_00165}.
CC   -!- SIMILARITY: Belongs to the thymidylate kinase family.
CC       {ECO:0000256|HAMAP-Rule:MF_00165}.
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DR   EMBL; CP001402; ACR41020.1; -; Genomic_DNA.
DR   RefSeq; WP_012710522.1; NC_012726.1.
DR   EnsemblBacteria; ACR41020; ACR41020; M164_0390.
DR   GeneID; 7812279; -.
DR   KEGG; sid:M164_0390; -.
DR   HOGENOM; HOG000270713; -.
DR   KO; K00943; -.
DR   OMA; LADRYIF; -.
DR   OrthoDB; POG093Z0CMW; -.
DR   BioCyc; SISL426118:GI01-393-MONOMER; -.
DR   Proteomes; UP000001479; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0004798; F:thymidylate kinase activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006233; P:dTDP biosynthetic process; IEA:InterPro.
DR   GO; GO:0006235; P:dTTP biosynthetic process; IEA:UniProtKB-HAMAP.
DR   HAMAP; MF_00165; Thymidylate_kinase; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR018094; Thymidylate_kinase.
DR   PANTHER; PTHR10344:SF4; PTHR10344:SF4; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
DR   PRODOM; C4KDP7.
DR   SWISS-2DPAGE; C4KDP7.
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00165};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001479};
KW   Kinase {ECO:0000256|HAMAP-Rule:MF_00165, ECO:0000313|EMBL:ACR41020.1};
KW   Nucleotide biosynthesis {ECO:0000256|HAMAP-Rule:MF_00165};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00165};
KW   Transferase {ECO:0000256|HAMAP-Rule:MF_00165}.
FT   NP_BIND       7     14       ATP. {ECO:0000256|HAMAP-Rule:MF_00165}.
SQ   SEQUENCE   205 AA;  23379 MW;  9FE96D709ABD4584 CRC64;
     MIIAFEGIEG SGKTSHLEAT KKYLEKQGYG VITFGLQKSK LLGERITQVK RNIVFERRTL
     FLAYVTDLAD QIENYVNPSI DSGFIALADG YTLTLTSWGL TRGLEKEWID DVLSILPKPS
     VSLPLISTPD EIVRRIIKKR GYLDPLETGI DICIKEDTFE AYIDYINRFQ EVLMSISSKE
     NIIYTDKEFD EVQKEIVRRI VSITS
//

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