(data stored in SCRATCH zone)

SWISSPROT: C4KDP8_SULIK

ID   C4KDP8_SULIK            Unreviewed;       213 AA.
AC   C4KDP8;
DT   07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   07-JUL-2009, sequence version 1.
DT   07-JUN-2017, entry version 36.
DE   RecName: Full=Probable thymidylate kinase {ECO:0000256|HAMAP-Rule:MF_00165};
DE            EC=2.7.4.9 {ECO:0000256|HAMAP-Rule:MF_00165};
DE   AltName: Full=dTMP kinase {ECO:0000256|HAMAP-Rule:MF_00165};
GN   Name=tmk {ECO:0000256|HAMAP-Rule:MF_00165};
GN   OrderedLocusNames=M164_0391 {ECO:0000313|EMBL:ACR41021.1};
OS   Sulfolobus islandicus (strain M.16.4 / Kamchatka #3).
OC   Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Sulfolobus.
OX   NCBI_TaxID=426118 {ECO:0000313|EMBL:ACR41021.1, ECO:0000313|Proteomes:UP000001479};
RN   [1] {ECO:0000313|EMBL:ACR41021.1, ECO:0000313|Proteomes:UP000001479}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=M.16.4 / Kamchatka #3 {ECO:0000313|Proteomes:UP000001479};
RX   PubMed=19435847; DOI=10.1073/pnas.0808945106;
RA   Reno M.L., Held N.L., Fields C.J., Burke P.V., Whitaker R.J.;
RT   "Biogeography of the Sulfolobus islandicus pan-genome.";
RL   Proc. Natl. Acad. Sci. U.S.A. 106:8605-8610(2009).
CC   -!- CATALYTIC ACTIVITY: ATP + dTMP = ADP + dTDP. {ECO:0000256|HAMAP-
CC       Rule:MF_00165}.
CC   -!- SIMILARITY: Belongs to the thymidylate kinase family.
CC       {ECO:0000256|HAMAP-Rule:MF_00165}.
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DR   EMBL; CP001402; ACR41021.1; -; Genomic_DNA.
DR   RefSeq; WP_012710523.1; NC_012726.1.
DR   EnsemblBacteria; ACR41021; ACR41021; M164_0391.
DR   GeneID; 8760216; -.
DR   KEGG; sid:M164_0391; -.
DR   HOGENOM; HOG000229077; -.
DR   KO; K00943; -.
DR   OMA; TAYARDS; -.
DR   OrthoDB; POG093Z0A1C; -.
DR   BioCyc; SISL426118:GI01-394-MONOMER; -.
DR   Proteomes; UP000001479; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0004798; F:thymidylate kinase activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006233; P:dTDP biosynthetic process; IEA:InterPro.
DR   GO; GO:0006235; P:dTTP biosynthetic process; IEA:UniProtKB-HAMAP.
DR   HAMAP; MF_00165; Thymidylate_kinase; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR018094; Thymidylate_kinase.
DR   PANTHER; PTHR10344:SF4; PTHR10344:SF4; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00041; DTMP_kinase; 1.
PE   3: Inferred from homology;
DR   PRODOM; C4KDP8.
DR   SWISS-2DPAGE; C4KDP8.
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00165};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001479};
KW   Kinase {ECO:0000256|HAMAP-Rule:MF_00165, ECO:0000313|EMBL:ACR41021.1};
KW   Nucleotide biosynthesis {ECO:0000256|HAMAP-Rule:MF_00165};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00165};
KW   Transferase {ECO:0000256|HAMAP-Rule:MF_00165,
KW   ECO:0000313|EMBL:ACR41021.1}.
FT   NP_BIND      10     17       ATP. {ECO:0000256|HAMAP-Rule:MF_00165}.
SQ   SEQUENCE   213 AA;  24803 MW;  638456DF7C687303 CRC64;
     MKGLLIAFEG IDGSGKSSQA VLLKDWIEMR RDVYLTEWNS SDWIHDIIKE AKKKNTLTPT
     TFSLIHATDF SDRYERFILP MLKSGFVVIC DRYIYTAYAR DVVRNVDFNW VKKLYSFAIK
     PNFTFYIRVT PEVALERIKK AKRKIKPQEA GIDILGELPL EEGFLKYQGM VVEIYDKIAK
     EESNFITIDG NRPLKDVQMD IRKILGEYID NSL
//

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