(data stored in SCRATCH zone)

SWISSPROT: C4KJG3_SULIK

ID   C4KJG3_SULIK            Unreviewed;       288 AA.
AC   C4KJG3;
DT   07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   07-JUL-2009, sequence version 1.
DT   07-JUN-2017, entry version 35.
DE   RecName: Full=1,4-dihydroxy-6-naphtoate synthase {ECO:0000256|HAMAP-Rule:MF_00996};
DE            EC=4.1.-.- {ECO:0000256|HAMAP-Rule:MF_00996};
DE   AltName: Full=Menaquinone biosynthetic enzyme MqnD {ECO:0000256|HAMAP-Rule:MF_00996};
GN   Name=mqnD {ECO:0000256|HAMAP-Rule:MF_00996};
GN   OrderedLocusNames=M164_0047 {ECO:0000313|EMBL:ACR40683.1};
OS   Sulfolobus islandicus (strain M.16.4 / Kamchatka #3).
OC   Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Sulfolobus.
OX   NCBI_TaxID=426118 {ECO:0000313|EMBL:ACR40683.1, ECO:0000313|Proteomes:UP000001479};
RN   [1] {ECO:0000313|EMBL:ACR40683.1, ECO:0000313|Proteomes:UP000001479}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=M.16.4 / Kamchatka #3 {ECO:0000313|Proteomes:UP000001479};
RX   PubMed=19435847; DOI=10.1073/pnas.0808945106;
RA   Reno M.L., Held N.L., Fields C.J., Burke P.V., Whitaker R.J.;
RT   "Biogeography of the Sulfolobus islandicus pan-genome.";
RL   Proc. Natl. Acad. Sci. U.S.A. 106:8605-8610(2009).
CC   -!- FUNCTION: Catalyzes the conversion of cyclic dehypoxanthine
CC       futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step
CC       in the biosynthesis of menaquinone (MK, vitamin K2).
CC       {ECO:0000256|HAMAP-Rule:MF_00996}.
CC   -!- PATHWAY: Quinol/quinone metabolism; menaquinone biosynthesis.
CC       {ECO:0000256|HAMAP-Rule:MF_00996}.
CC   -!- SIMILARITY: Belongs to the MqnA/MqnD family. MqnD subfamily.
CC       {ECO:0000256|HAMAP-Rule:MF_00996}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|HAMAP-Rule:MF_00996}.
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DR   EMBL; CP001402; ACR40683.1; -; Genomic_DNA.
DR   RefSeq; WP_012710226.1; NC_012726.1.
DR   ProteinModelPortal; C4KJG3; -.
DR   EnsemblBacteria; ACR40683; ACR40683; M164_0047.
DR   GeneID; 7812107; -.
DR   KEGG; sid:M164_0047; -.
DR   HOGENOM; HOG000270636; -.
DR   OMA; RGCGPLV; -.
DR   OrthoDB; POG093Z0791; -.
DR   BioCyc; SISL426118:GI01-47-MONOMER; -.
DR   UniPathway; UPA00079; -.
DR   Proteomes; UP000001479; Chromosome.
DR   GO; GO:0016830; F:carbon-carbon lyase activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0009234; P:menaquinone biosynthetic process; IEA:UniProtKB-HAMAP.
DR   HAMAP; MF_00996; MqnD; 1.
DR   InterPro; IPR003773; Menaquinone_biosynth.
DR   InterPro; IPR030869; MqnD.
DR   Pfam; PF02621; VitK2_biosynth; 1.
PE   3: Inferred from homology;
DR   PRODOM; C4KJG3.
DR   SWISS-2DPAGE; C4KJG3.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001479};
KW   Lyase {ECO:0000256|HAMAP-Rule:MF_00996};
KW   Menaquinone biosynthesis {ECO:0000256|HAMAP-Rule:MF_00996}.
FT   REGION      113    114       Substrate binding. {ECO:0000256|HAMAP-
FT                                Rule:MF_00996}.
FT   ACT_SITE    152    152       Proton acceptor. {ECO:0000256|HAMAP-Rule:
FT                                MF_00996}.
SQ   SEQUENCE   288 AA;  32773 MW;  FD8831A08386DD36 CRC64;
     MVTIRVGALA DSGDLYPFIP LMEGKVRPEG FNLEFEVIPT VQDINEAVLK KEVDVSVPSA
     AMYPYIQDDY YILSNAVATA VDGITGMPIL AIKEMSENEI KRSRLIVHGP NTTAFTLYKL
     LMGKYGRLVI IRRVLDEIKA LGKEGDVLVA VHEIKMMYAL KKLGINVVRI GSMWDMWKAI
     SNNTPMPMGM VVISKEVGKD FALKFKETYE KSKKYAEKHL DEIIPRDVQI MRESQKADLD
     EEIVRKTIWA DIQEYNVPVD EVRRGLEFFF KISEERGILP RVKSIDLL
//

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