(data stored in SCRATCH zone)

SWISSPROT: C4KKT8_SULIK

ID   C4KKT8_SULIK            Unreviewed;       715 AA.
AC   C4KKT8;
DT   07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   07-JUL-2009, sequence version 1.
DT   07-JUN-2017, entry version 54.
DE   RecName: Full=ATP-dependent DNA helicase Hel308 {ECO:0000256|HAMAP-Rule:MF_00442};
DE            EC=3.6.4.12 {ECO:0000256|HAMAP-Rule:MF_00442};
GN   Name=hel308 {ECO:0000256|HAMAP-Rule:MF_00442};
GN   OrderedLocusNames=M164_0269 {ECO:0000313|EMBL:ACR40903.1};
OS   Sulfolobus islandicus (strain M.16.4 / Kamchatka #3).
OC   Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Sulfolobus.
OX   NCBI_TaxID=426118 {ECO:0000313|EMBL:ACR40903.1, ECO:0000313|Proteomes:UP000001479};
RN   [1] {ECO:0000313|EMBL:ACR40903.1, ECO:0000313|Proteomes:UP000001479}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=M.16.4 / Kamchatka #3 {ECO:0000313|Proteomes:UP000001479};
RX   PubMed=19435847; DOI=10.1073/pnas.0808945106;
RA   Reno M.L., Held N.L., Fields C.J., Burke P.V., Whitaker R.J.;
RT   "Biogeography of the Sulfolobus islandicus pan-genome.";
RL   Proc. Natl. Acad. Sci. U.S.A. 106:8605-8610(2009).
CC   -!- FUNCTION: DNA-dependent ATPase and 3'-5' DNA helicase that may be
CC       involved in repair of stalled replication forks.
CC       {ECO:0000256|HAMAP-Rule:MF_00442}.
CC   -!- CATALYTIC ACTIVITY: ATP + H(2)O = ADP + phosphate.
CC       {ECO:0000256|HAMAP-Rule:MF_00442}.
CC   -!- SUBUNIT: Monomer. {ECO:0000256|HAMAP-Rule:MF_00442}.
CC   -!- SIMILARITY: Belongs to the helicase family. Hel308 subfamily.
CC       {ECO:0000256|HAMAP-Rule:MF_00442}.
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DR   EMBL; CP001402; ACR40903.1; -; Genomic_DNA.
DR   RefSeq; WP_012735437.1; NC_012726.1.
DR   EnsemblBacteria; ACR40903; ACR40903; M164_0269.
DR   KEGG; sid:M164_0269; -.
DR   HOGENOM; HOG000227028; -.
DR   KO; K03726; -.
DR   OMA; NSNERGD; -.
DR   OrthoDB; POG093Z00MB; -.
DR   BioCyc; SISL426118:GI01-271-MONOMER; -.
DR   Proteomes; UP000001479; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-HAMAP.
DR   HAMAP; MF_00442; Helicase_Hel308; 1.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR022965; Helicase_Hel308.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014014; RNA_helicase_DEAD_Q_motif.
DR   InterPro; IPR011991; WHTH_DNA-bd_dom.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF52540; SSF52540; 3.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
DR   PROSITE; PS51195; Q_MOTIF; 1.
PE   3: Inferred from homology;
DR   PRODOM; C4KKT8.
DR   SWISS-2DPAGE; C4KKT8.
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00442};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001479};
KW   DNA damage {ECO:0000256|HAMAP-Rule:MF_00442};
KW   DNA repair {ECO:0000256|HAMAP-Rule:MF_00442};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00442};
KW   Helicase {ECO:0000256|HAMAP-Rule:MF_00442,
KW   ECO:0000313|EMBL:ACR40903.1};
KW   Hydrolase {ECO:0000256|HAMAP-Rule:MF_00442};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00442}.
FT   DOMAIN        8     36       Q_MOTIF. {ECO:0000259|PROSITE:PS51195}.
FT   DOMAIN       40    203       Helicase ATP-binding.
FT                                {ECO:0000259|PROSITE:PS51192}.
FT   DOMAIN      236    442       Helicase C-terminal.
FT                                {ECO:0000259|PROSITE:PS51194}.
FT   MOTIF         8     36       Q motif. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00552}.
FT   BINDING      35     35       ATP. {ECO:0000256|HAMAP-Rule:MF_00442}.
SQ   SEQUENCE   715 AA;  81408 MW;  17F1D2EB2D8B72CB CRC64;
     MSLELEWMSI DDLKLPSNVI DIIKNRGIKK LNPPQTEAVK KGLLDGNRLL LTSPTGSGKT
     LIAEMGIISF LLKNGGKAIY VTPLRALTNE KYLTFKDWES IGFKVAMTSG DYDTDDAWLK
     NYDIIITTYE KLDSLWRHRP DWLNEANYFV LDELHYLNDP ERGPVVESVT IRTKRRNLLA
     LSATISNYKQ IAKWLGAEPV ATNWRPVPLM EGIMYPEKKK KEYTILFRDN TTRKVHGDDA
     IIAYTLDSLT KNGQVLVFRN SRKMAESTAL KIANYMNFVS LDEKAISEIL NQLDDIEEGG
     SDEKELLKSL ISKGVAYHHA GLSKALRDII EESFRKRKIK VIVATPTLAA GVNLPARTVI
     IGDIYRFNRK IVGYYDEIPV MEYKQMSGRA GRPGFDQIGE SIIVVRDKED VDRVFKKYIL
     SDVEPIESKL GSERAFYTFL LGILSAEGSL SEKQLEGFAY ESLLAKSLVD VYFDRAIRWL
     SEHSFIREEN NTFTLTNFGK RVADLYINPF TADIIRKGLE GHKASCEIAY LHLLAFTPDG
     PLVSVGRNEE EELIELLEDL ECELLVEEPY EEDEYSLYLN ALKVALIMKD WIDEVDEDTI
     LGKYNIGSGD LRNIVETMDW LTYSAYHLSK ELRLDNHSDK LRILNLRVTD GVKEELLELV
     QIGGVGRKRA RLLYNNGIKG LGDVVMNPDR VRNLLGQKLG ERVVQEAARL LNRFH
//

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