(data stored in ACNUC22857 zone)

SWISSPROT: C4R3H6_KOMPG

ID   C4R3H6_KOMPG            Unreviewed;       716 AA.
AC   C4R3H6;
DT   07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   07-JUL-2009, sequence version 1.
DT   07-JUN-2017, entry version 48.
DE   RecName: Full=AP complex subunit beta {ECO:0000256|PIRNR:PIRNR002291};
GN   OrderedLocusNames=PAS_chr3_0079 {ECO:0000313|EMBL:CAY70011.1};
OS   Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia
OS   pastoris).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
OC   Saccharomycetes; Saccharomycetales; Phaffomycetaceae; Komagataella.
OX   NCBI_TaxID=644223 {ECO:0000313|EMBL:CAY70011.1, ECO:0000313|Proteomes:UP000000314};
RN   [1] {ECO:0000313|EMBL:CAY70011.1, ECO:0000313|Proteomes:UP000000314}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GS115 / ATCC 20864 {ECO:0000313|Proteomes:UP000000314};
RX   PubMed=19465926; DOI=10.1038/nbt.1544;
RA   De Schutter K., Lin Y.-C., Tiels P., Van Hecke A., Glinka S.,
RA   Weber-Lehmann J., Rouze P., Van de Peer Y., Callewaert N.;
RT   "Genome sequence of the recombinant protein production host Pichia
RT   pastoris.";
RL   Nat. Biotechnol. 27:561-566(2009).
CC   -!- FUNCTION: Adaptins are components of the adaptor complexes which
CC       link clathrin to receptors in coated vesicles. Clathrin-associated
CC       protein complexes are believed to interact with the cytoplasmic
CC       tails of membrane proteins, leading to their selection and
CC       concentration. {ECO:0000256|PIRNR:PIRNR002291}.
CC   -!- SIMILARITY: Belongs to the adaptor complexes large subunit family.
CC       {ECO:0000256|PIRNR:PIRNR002291}.
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DR   EMBL; FN392321; CAY70011.1; -; Genomic_DNA.
DR   RefSeq; XP_002492291.1; XM_002492246.1.
DR   ProteinModelPortal; C4R3H6; -.
DR   STRING; 644223.XP_002492291.1; -.
DR   EnsemblFungi; CAY70011; CAY70011; PAS_chr3_0079.
DR   GeneID; 8199364; -.
DR   KEGG; ppa:PAS_chr3_0079; -.
DR   eggNOG; KOG1061; Eukaryota.
DR   eggNOG; COG5096; LUCA.
DR   HOGENOM; HOG000163270; -.
DR   InParanoid; C4R3H6; -.
DR   OMA; PSLQHEN; -.
DR   OrthoDB; EOG092C18N0; -.
DR   Proteomes; UP000000314; Chromosome 3.
DR   GO; GO:0030117; C:membrane coat; IEA:InterPro.
DR   GO; GO:0008565; F:protein transporter activity; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   Gene3D; 1.25.10.10; -; 1.
DR   InterPro; IPR026739; AP_beta.
DR   InterPro; IPR016342; AP_complex_bsu_1_2_4.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR002553; Clathrin/coatomer_adapt-like_N.
DR   PANTHER; PTHR11134; PTHR11134; 1.
DR   Pfam; PF01602; Adaptin_N; 1.
DR   PIRSF; PIRSF002291; AP_complex_beta; 1.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   3: Inferred from homology;
DR   PRODOM; C4R3H6.
DR   SWISS-2DPAGE; C4R3H6.
KW   Complete proteome {ECO:0000313|Proteomes:UP000000314};
KW   Membrane {ECO:0000256|PIRNR:PIRNR002291,
KW   ECO:0000256|SAAS:SAAS00101884};
KW   Protein transport {ECO:0000256|PIRNR:PIRNR002291,
KW   ECO:0000256|SAAS:SAAS00468902};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000314};
KW   Transport {ECO:0000256|PIRNR:PIRNR002291,
KW   ECO:0000256|SAAS:SAAS00299740}.
FT   DOMAIN       21    548       Adaptin_N. {ECO:0000259|Pfam:PF01602}.
SQ   SEQUENCE   716 AA;  81583 MW;  C90B2E55B3061F1D CRC64;
     MVNDSKYFVK CRGSELLAEF REATNSKKEK NTLLKKKNVL KKFLANITVE STDIIDVFTE
     VIKLYKEAQQ SSLDQELRVM IYHCLRSTNH YRSEDREQVI ELLLRDYYSK SIPAHIKGLA
     LQTLTSIPNE HFIQASIPAV KKSLHDQDPH VRKTGCFCVA RIYEFDLQIG NDAHLIDHLN
     DKLDDGNPSV VSSALVALSD ITEKVEEFEF SISEDHAFEL LDILPTINEW AQASSLSSIL
     YFAPDSQATA CEIIDKVLPY LQQSNNEVVL NALKVIIYMS NYIMHPEDLI PQLPKRIGSA
     LVSVLNSGPE IQFLLLRNTI LLLLSKFNLV SLNVTSFFCR YNDPIYIKDT KLEIIYLLAN
     EENLHIILEE LEEYARDSDV QMSRKAIRAI GNLAIKLEDI ATDAVLVLSD LIESKVPHIL
     QEVVVVFKRI VRRYPYLHSK MLNNLMENID MIEEPGSKLA IVWLIGEYNT AMEKNAVSLL
     KKIGQNFRED NSEVQLAFLT ALIKVYLNFS ADKMCEDLVV ETFRTATEDI GNIDVRERGF
     YYWRLLSNRR DFPNAIEEIV NAKLPVISSD PDNLDTRVLE ELEMNIGTLA SIYLKPVSHV
     FRLNKVKELQ HTSALKREHS SVFAAQKNHS SKTLRLRSSS SLTYRNKSAS SLTPIEAEFK
     FNRQQAGQRY SSSKADDTDS DTMVGSLDIS GSRKQKNSLG LTRRMSKLGR KLTISR
//

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