(data stored in SCRATCH zone)

SWISSPROT: C5BBC1_EDWI9

ID   C5BBC1_EDWI9            Unreviewed;       231 AA.
AC   C5BBC1;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   07-JUN-2017, entry version 51.
DE   RecName: Full=dTDP-fucosamine acetyltransferase {ECO:0000256|HAMAP-Rule:MF_02027};
DE            EC=2.3.1.210 {ECO:0000256|HAMAP-Rule:MF_02027};
DE   AltName: Full=TDP-fucosamine acetyltransferase {ECO:0000256|HAMAP-Rule:MF_02027};
DE   AltName: Full=dTDP-4-amino-4,6-dideoxy-D-galactose acyltransferase {ECO:0000256|HAMAP-Rule:MF_02027};
GN   Name=wecD {ECO:0000256|HAMAP-Rule:MF_02027};
GN   OrderedLocusNames=NT01EI_0096 {ECO:0000313|EMBL:ACR67356.1};
OS   Edwardsiella ictaluri (strain 93-146).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Hafniaceae; Edwardsiella.
OX   NCBI_TaxID=634503 {ECO:0000313|EMBL:ACR67356.1, ECO:0000313|Proteomes:UP000001485};
RN   [1] {ECO:0000313|Proteomes:UP000001485}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=93-146 {ECO:0000313|Proteomes:UP000001485};
RA   Williams M.L., Gillaspy A.F., Dyer D.W., Thune R.L., Waldbieser G.C.,
RA   Schuster S.C., Gipson J., Zaitshik J., Landry C., Lawrence M.L.;
RT   "Complete genome sequence of Edwardsiella ictaluri 93-146.";
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-
CC       amino-4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized
CC       in the biosynthesis of the enterobacterial common antigen (ECA).
CC       {ECO:0000256|HAMAP-Rule:MF_02027}.
CC   -!- CATALYTIC ACTIVITY: Acetyl-CoA + dTDP-4-amino-4,6-dideoxy-alpha-D-
CC       galactose = CoA + dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose.
CC       {ECO:0000256|HAMAP-Rule:MF_02027}.
CC   -!- PATHWAY: Bacterial outer membrane biogenesis; enterobacterial
CC       common antigen biosynthesis. {ECO:0000256|HAMAP-Rule:MF_02027}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000256|HAMAP-Rule:MF_02027}.
CC   -!- SIMILARITY: Belongs to the WecD family. {ECO:0000256|HAMAP-
CC       Rule:MF_02027}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|HAMAP-Rule:MF_02027}.
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DR   EMBL; CP001600; ACR67356.1; -; Genomic_DNA.
DR   RefSeq; WP_015869575.1; NC_012779.2.
DR   ProteinModelPortal; C5BBC1; -.
DR   STRING; 634503.NT01EI_0096; -.
DR   EnsemblBacteria; ACR67356; ACR67356; NT01EI_0096.
DR   GeneID; 7959815; -.
DR   KEGG; eic:NT01EI_0096; -.
DR   PATRIC; fig|634503.3.peg.90; -.
DR   eggNOG; ENOG4108WJ1; Bacteria.
DR   eggNOG; COG0454; LUCA.
DR   HOGENOM; HOG000126448; -.
DR   KO; K16704; -.
DR   OMA; TAYWFYR; -.
DR   OrthoDB; POG091H0HEA; -.
DR   UniPathway; UPA00566; -.
DR   Proteomes; UP000001485; Chromosome.
DR   GO; GO:0008080; F:N-acetyltransferase activity; IEA:InterPro.
DR   GO; GO:0009246; P:enterobacterial common antigen biosynthetic process; IEA:UniProtKB-HAMAP.
DR   HAMAP; MF_02027; WecD_RffC; 1.
DR   InterPro; IPR012752; AcTrfase_WecD.
DR   InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR   InterPro; IPR000182; GNAT_dom.
DR   Pfam; PF00583; Acetyltransf_1; 1.
DR   SUPFAM; SSF55729; SSF55729; 1.
DR   TIGRFAMs; TIGR02382; wecD_rffC; 1.
DR   PROSITE; PS51186; GNAT; 1.
PE   3: Inferred from homology;
DR   PRODOM; C5BBC1.
DR   SWISS-2DPAGE; C5BBC1.
KW   Acyltransferase {ECO:0000256|HAMAP-Rule:MF_02027};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001485};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001485};
KW   Transferase {ECO:0000256|HAMAP-Rule:MF_02027,
KW   ECO:0000313|EMBL:ACR67356.1}.
FT   DOMAIN       95    231       N-acetyltransferase.
FT                                {ECO:0000259|PROSITE:PS51186}.
FT   ACT_SITE    215    215       Proton donor. {ECO:0000256|HAMAP-Rule:
FT                                MF_02027}.
FT   BINDING     208    208       Acetyl-CoA. {ECO:0000256|HAMAP-Rule:
FT                                MF_02027}.
SQ   SEQUENCE   231 AA;  25385 MW;  DBECC3CB8FC0B544 CRC64;
     MSVHASIEPL AWESAFFALR SGRLMFDDRA PPLLASACDA YQLLQAKVDA RDLARCDALQ
     ALGFRLAEGE ADFILPISSA SASGGQRQAQ AQDCLWLRAL ARDAFALSRF RAPWYRDGES
     ARFYAEWVEK AVYGTFDHAC LLALDNEGNP QGFVTLRRQV DGSARIGLLA VDGASFRGGV
     GRRLVTQAQA WCHAQRLSRL HVATQIGNLA AQRLYLGCGA QLTATAYWLY R
//

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