(data stored in SCRATCH zone)

SWISSPROT: C5BBC3_EDWI9

ID   C5BBC3_EDWI9            Unreviewed;       416 AA.
AC   C5BBC3;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   07-JUN-2017, entry version 45.
DE   RecName: Full=Lipid III flippase {ECO:0000256|HAMAP-Rule:MF_02024};
GN   Name=wzxE {ECO:0000256|HAMAP-Rule:MF_02024};
GN   OrderedLocusNames=NT01EI_0098 {ECO:0000313|EMBL:ACR67358.1};
OS   Edwardsiella ictaluri (strain 93-146).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Hafniaceae; Edwardsiella.
OX   NCBI_TaxID=634503 {ECO:0000313|EMBL:ACR67358.1, ECO:0000313|Proteomes:UP000001485};
RN   [1] {ECO:0000313|Proteomes:UP000001485}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=93-146 {ECO:0000313|Proteomes:UP000001485};
RA   Williams M.L., Gillaspy A.F., Dyer D.W., Thune R.L., Waldbieser G.C.,
RA   Schuster S.C., Gipson J., Zaitshik J., Landry C., Lawrence M.L.;
RT   "Complete genome sequence of Edwardsiella ictaluri 93-146.";
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Mediates the transbilayer movement of Und-PP-GlcNAc-
CC       ManNAcA-Fuc4NAc (lipid III) from the inner to the outer leaflet of
CC       the cytoplasmic membrane during the assembly of enterobacterial
CC       common antigen (ECA). {ECO:0000256|HAMAP-Rule:MF_02024}.
CC   -!- PATHWAY: Bacterial outer membrane biogenesis; enterobacterial
CC       common antigen biosynthesis. {ECO:0000256|HAMAP-Rule:MF_02024}.
CC   -!- SUBUNIT: Probably part of a complex composed of WzxE, WzyE and
CC       WzzE. {ECO:0000256|HAMAP-Rule:MF_02024}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000256|HAMAP-
CC       Rule:MF_02024}; Multi-pass membrane protein {ECO:0000256|HAMAP-
CC       Rule:MF_02024}.
CC   -!- SIMILARITY: Belongs to the polysaccharide transport (PST) (TC
CC       2.A.66.2) family. {ECO:0000256|HAMAP-Rule:MF_02024}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CP001600; ACR67358.1; -; Genomic_DNA.
DR   RefSeq; WP_015869577.1; NC_012779.2.
DR   STRING; 634503.NT01EI_0098; -.
DR   EnsemblBacteria; ACR67358; ACR67358; NT01EI_0098.
DR   GeneID; 7959817; -.
DR   KEGG; eic:NT01EI_0098; -.
DR   PATRIC; fig|634503.3.peg.92; -.
DR   eggNOG; ENOG4105EGZ; Bacteria.
DR   eggNOG; COG2244; LUCA.
DR   HOGENOM; HOG000126459; -.
DR   KO; K16693; -.
DR   OMA; KFTIMAL; -.
DR   OrthoDB; POG091H0HEN; -.
DR   UniPathway; UPA00566; -.
DR   Proteomes; UP000001485; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-HAMAP.
DR   GO; GO:0009246; P:enterobacterial common antigen biosynthetic process; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
DR   HAMAP; MF_02024; WzxE; 1.
DR   InterPro; IPR002797; Polysacc_synth.
DR   InterPro; IPR032896; WzxE.
DR   Pfam; PF01943; Polysacc_synt; 1.
PE   3: Inferred from homology;
DR   PRODOM; C5BBC3.
DR   SWISS-2DPAGE; C5BBC3.
KW   Cell inner membrane {ECO:0000256|HAMAP-Rule:MF_02024};
KW   Cell membrane {ECO:0000256|HAMAP-Rule:MF_02024};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001485};
KW   Membrane {ECO:0000256|HAMAP-Rule:MF_02024};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001485};
KW   Transmembrane {ECO:0000256|HAMAP-Rule:MF_02024};
KW   Transmembrane helix {ECO:0000256|HAMAP-Rule:MF_02024};
KW   Transport {ECO:0000256|HAMAP-Rule:MF_02024}.
FT   TRANSMEM     12     33       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_02024}.
FT   TRANSMEM     45     67       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_02024}.
FT   TRANSMEM     79    105       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_02024}.
FT   TRANSMEM    117    137       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_02024}.
FT   TRANSMEM    149    169       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_02024}.
FT   TRANSMEM    175    195       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_02024}.
FT   TRANSMEM    216    238       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_02024}.
FT   TRANSMEM    263    283       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_02024}.
FT   TRANSMEM    295    314       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_02024}.
FT   TRANSMEM    334    355       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_02024}.
FT   TRANSMEM    362    382       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_02024}.
FT   TRANSMEM    394    412       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_02024}.
SQ   SEQUENCE   416 AA;  45273 MW;  A3BF3BE98F808B56 CRC64;
     MSLARASLWT AGSTLIKIGA GLVVVKLLAV AFGPVGVGQA ANFRQVITVL GVLSGAGIFN
     GITKYVAEYR QQPLRLRALL GTASTMILGF SLLLALIFTL GAAPISVALF GHDDYQAVIR
     LVALLQMGIA CANYCLAVIK GYRDARGNAL AVALGSLLGV AAYTLSYFWG GYRGALAGLA
     LVPAVATLPA LWVLWRQRHI PWRYFRPSWD RPLAAGLGKF TLMAVMTAVT MPVAYVMMRN
     QLAALDGWEA VGIWQGVSGI SDAYLQFITA SFSVYLLPTL AGLRSRQAVG QEILRALRFV
     LPAVAAVSFM VWLLRDLVIW LLLSGKFSAM RDLFAWQLTG DVFKVGAYVF GYLVIAKASL
     RFYLLCEISQ FILLTLLSRF LIPQHGALGA AQAYMATYII YFLLCGSVFW IYRNRA
//

If you have problems or comments...

PBIL Back to PBIL home page