(data stored in SCRATCH zone)

SWISSPROT: C5BBC4_EDWI9

ID   C5BBC4_EDWI9            Unreviewed;       358 AA.
AC   C5BBC4;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   07-JUN-2017, entry version 55.
DE   RecName: Full=TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase {ECO:0000256|HAMAP-Rule:MF_01002};
DE            EC=2.4.1.325 {ECO:0000256|HAMAP-Rule:MF_01002};
DE   AltName: Full=4-alpha-L-fucosyltransferase {ECO:0000256|HAMAP-Rule:MF_01002};
DE   AltName: Full=TDP-Fuc4NAc:lipid II Fuc4NAc transferase {ECO:0000256|HAMAP-Rule:MF_01002};
DE            Short=Fuc4NAc transferase {ECO:0000256|HAMAP-Rule:MF_01002};
GN   Name=wecF {ECO:0000256|HAMAP-Rule:MF_01002};
GN   Synonyms=rffT {ECO:0000256|HAMAP-Rule:MF_01002};
GN   OrderedLocusNames=NT01EI_0099 {ECO:0000313|EMBL:ACR67359.1};
OS   Edwardsiella ictaluri (strain 93-146).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Hafniaceae; Edwardsiella.
OX   NCBI_TaxID=634503 {ECO:0000313|EMBL:ACR67359.1, ECO:0000313|Proteomes:UP000001485};
RN   [1] {ECO:0000313|Proteomes:UP000001485}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=93-146 {ECO:0000313|Proteomes:UP000001485};
RA   Williams M.L., Gillaspy A.F., Dyer D.W., Thune R.L., Waldbieser G.C.,
RA   Schuster S.C., Gipson J., Zaitshik J., Landry C., Lawrence M.L.;
RT   "Complete genome sequence of Edwardsiella ictaluri 93-146.";
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc
CC       (Lipid III), the third lipid-linked intermediate involved in ECA
CC       synthesis. {ECO:0000256|HAMAP-Rule:MF_01002,
CC       ECO:0000256|SAAS:SAAS00646115}.
CC   -!- CATALYTIC ACTIVITY: dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose
CC       + N-acetyl-beta-D-mannosaminouronyl-(1->4)-N-acetyl-alpha-D-
CC       glucosaminyl-diphospho-ditrans,octacis-undecaprenol = dTDP + 4-
CC       acetamido-4,6-dideoxy-alpha-D-galactosyl-(1->4)-N-acetyl-beta-D-
CC       mannosaminouronyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-
CC       ditrans,octacis-undecaprenol. {ECO:0000256|HAMAP-Rule:MF_01002,
CC       ECO:0000256|SAAS:SAAS00646124}.
CC   -!- PATHWAY: Bacterial outer membrane biogenesis; enterobacterial
CC       common antigen biosynthesis. {ECO:0000256|HAMAP-Rule:MF_01002,
CC       ECO:0000256|SAAS:SAAS00646127}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000256|HAMAP-
CC       Rule:MF_01002, ECO:0000256|SAAS:SAAS00646120}; Peripheral membrane
CC       protein {ECO:0000256|HAMAP-Rule:MF_01002,
CC       ECO:0000256|SAAS:SAAS00646120}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 56 family.
CC       {ECO:0000256|HAMAP-Rule:MF_01002, ECO:0000256|SAAS:SAAS00646125}.
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DR   EMBL; CP001600; ACR67359.1; -; Genomic_DNA.
DR   RefSeq; WP_015869578.1; NC_012779.2.
DR   STRING; 634503.NT01EI_0099; -.
DR   CAZy; GT56; Glycosyltransferase Family 56.
DR   EnsemblBacteria; ACR67359; ACR67359; NT01EI_0099.
DR   GeneID; 7959818; -.
DR   KEGG; eic:NT01EI_0099; -.
DR   PATRIC; fig|634503.3.peg.93; -.
DR   eggNOG; ENOG4105F18; Bacteria.
DR   eggNOG; ENOG410XT9P; LUCA.
DR   HOGENOM; HOG000249654; -.
DR   KO; K12582; -.
DR   OMA; VIVPMGY; -.
DR   OrthoDB; POG091H0HXS; -.
DR   UniPathway; UPA00566; -.
DR   Proteomes; UP000001485; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0102031; F:4-acetamido-4,6-dideoxy-D-galactose transferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008417; F:fucosyltransferase activity; IEA:InterPro.
DR   GO; GO:0009246; P:enterobacterial common antigen biosynthetic process; IEA:UniProtKB-HAMAP.
DR   HAMAP; MF_01002; WecF_RffT; 1.
DR   InterPro; IPR009993; WecF.
DR   Pfam; PF07429; Glyco_transf_56; 1.
PE   3: Inferred from homology;
DR   PRODOM; C5BBC4.
DR   SWISS-2DPAGE; C5BBC4.
KW   Cell inner membrane {ECO:0000256|HAMAP-Rule:MF_01002,
KW   ECO:0000256|SAAS:SAAS00646128};
KW   Cell membrane {ECO:0000256|HAMAP-Rule:MF_01002,
KW   ECO:0000256|SAAS:SAAS00646126};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001485};
KW   Glycosyltransferase {ECO:0000256|HAMAP-Rule:MF_01002,
KW   ECO:0000256|SAAS:SAAS00646116, ECO:0000313|EMBL:ACR67359.1};
KW   Membrane {ECO:0000256|HAMAP-Rule:MF_01002,
KW   ECO:0000256|SAAS:SAAS00646113};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001485};
KW   Transferase {ECO:0000256|HAMAP-Rule:MF_01002,
KW   ECO:0000256|SAAS:SAAS00646112, ECO:0000313|EMBL:ACR67359.1}.
SQ   SEQUENCE   358 AA;  40797 MW;  ED397A1CDCE8502E CRC64;
     MTTLIHVLGA DIPHHNLTLL RFFDGVLSQR AATAPRRRFM VVARDAAPFA ALTTLDIEVW
     PDKRALARAL LARARADRTL RFFLHGQFNP WLWLALLCGR LRPQQVLWHV WGADLYEEAR
     GWKYRLYYGL RRLAQGRVGH VFATQGDLDY YRQRHPRVAT STLYFPTRMD PALTCNQRVR
     ETSGALTVLV GNSGDRSNRH LVALQRLHDT FGPQTRVIVP LGYPANNQAY IAQVRERAES
     LFGHNATLLT QQVAFTDYLA LLARCDLGYF IFERQQGIGT LCLLLQQGIP PVLSRQNPFW
     RDMAAQQLPV LFDDDAPDDV AVRAAQRQLA LRDLSQIAFF DPNYIDGWLQ ALALGERP
//

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