(data stored in SCRATCH zone)

SWISSPROT: C5BBC6_EDWI9

ID   C5BBC6_EDWI9            Unreviewed;       246 AA.
AC   C5BBC6;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   07-JUN-2017, entry version 57.
DE   RecName: Full=UDP-N-acetyl-D-mannosaminuronic acid transferase {ECO:0000256|HAMAP-Rule:MF_01001, ECO:0000256|SAAS:SAAS00727171};
DE            Short=UDP-ManNAcA transferase {ECO:0000256|HAMAP-Rule:MF_01001};
DE            EC=2.4.1.180 {ECO:0000256|HAMAP-Rule:MF_01001, ECO:0000256|SAAS:SAAS00727172};
GN   Name=wecG {ECO:0000256|HAMAP-Rule:MF_01001};
GN   Synonyms=rffM {ECO:0000256|HAMAP-Rule:MF_01001};
GN   OrderedLocusNames=NT01EI_0101 {ECO:0000313|EMBL:ACR67361.1};
OS   Edwardsiella ictaluri (strain 93-146).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Hafniaceae; Edwardsiella.
OX   NCBI_TaxID=634503 {ECO:0000313|EMBL:ACR67361.1, ECO:0000313|Proteomes:UP000001485};
RN   [1] {ECO:0000313|Proteomes:UP000001485}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=93-146 {ECO:0000313|Proteomes:UP000001485};
RA   Williams M.L., Gillaspy A.F., Dyer D.W., Thune R.L., Waldbieser G.C.,
RA   Schuster S.C., Gipson J., Zaitshik J., Landry C., Lawrence M.L.;
RT   "Complete genome sequence of Edwardsiella ictaluri 93-146.";
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid
CC       II), the second lipid-linked intermediate involved in
CC       enterobacterial common antigen (ECA) synthesis.
CC       {ECO:0000256|HAMAP-Rule:MF_01001, ECO:0000256|SAAS:SAAS00727166}.
CC   -!- CATALYTIC ACTIVITY: UDP-N-acetyl-alpha-D-mannosaminouronate + N-
CC       acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
CC       = UDP + N-acetyl-beta-D-mannosaminouronyl-(1->4)-N-acetyl-alpha-D-
CC       glucosaminyl-diphospho-ditrans,octacis-undecaprenol.
CC       {ECO:0000256|HAMAP-Rule:MF_01001, ECO:0000256|SAAS:SAAS00727176}.
CC   -!- PATHWAY: Bacterial outer membrane biogenesis; enterobacterial
CC       common antigen biosynthesis. {ECO:0000256|HAMAP-Rule:MF_01001,
CC       ECO:0000256|SAAS:SAAS00727167}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 26 family.
CC       {ECO:0000256|HAMAP-Rule:MF_01001, ECO:0000256|SAAS:SAAS00768719}.
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DR   EMBL; CP001600; ACR67361.1; -; Genomic_DNA.
DR   RefSeq; WP_015869580.1; NC_012779.2.
DR   STRING; 634503.NT01EI_0101; -.
DR   CAZy; GT26; Glycosyltransferase Family 26.
DR   EnsemblBacteria; ACR67361; ACR67361; NT01EI_0101.
DR   GeneID; 7959820; -.
DR   KEGG; eic:NT01EI_0101; -.
DR   PATRIC; fig|634503.3.peg.95; -.
DR   eggNOG; ENOG4108UHC; Bacteria.
DR   eggNOG; COG1922; LUCA.
DR   HOGENOM; HOG000075380; -.
DR   KO; K02852; -.
DR   OMA; PWRWRRM; -.
DR   OrthoDB; POG091H00MT; -.
DR   UniPathway; UPA00566; -.
DR   Proteomes; UP000001485; Chromosome.
DR   GO; GO:0047241; F:lipopolysaccharide N-acetylmannosaminouronosyltransferase activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0009246; P:enterobacterial common antigen biosynthetic process; IEA:UniProtKB-HAMAP.
DR   CDD; cd06533; Glyco_transf_WecG_TagA; 1.
DR   Gene3D; 3.20.20.70; -; 1.
DR   HAMAP; MF_01001; WecG_RffM; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR023085; UDP-ManNAcA_Trfase_WecG.
DR   InterPro; IPR004629; WecB_TagA_CpsF.
DR   PANTHER; PTHR34136; PTHR34136; 1.
DR   Pfam; PF03808; Glyco_tran_WecB; 1.
DR   TIGRFAMs; TIGR00696; wecG_tagA_cpsF; 1.
PE   3: Inferred from homology;
DR   PRODOM; C5BBC6.
DR   SWISS-2DPAGE; C5BBC6.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001485};
KW   Glycosyltransferase {ECO:0000256|HAMAP-Rule:MF_01001,
KW   ECO:0000256|SAAS:SAAS00768725, ECO:0000313|EMBL:ACR67361.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001485};
KW   Transferase {ECO:0000256|HAMAP-Rule:MF_01001,
KW   ECO:0000256|SAAS:SAAS00768714, ECO:0000313|EMBL:ACR67361.1}.
SQ   SEQUENCE   246 AA;  27788 MW;  185638FA5FA651CD CRC64;
     MESNGSIPHY AIRGIDIWGF RDSEQFLRHL LMESAVRPGT LVAMNAEKVM TAEDDAALRT
     LIAAAEYKYA DGISIVRAIR RKYPGAQVSR IAGADLWEAL MQRAGELGIP VFLVGGQSDV
     LAQTEAVLRC RWGVNVVGAQ DGYFPSDQRD ALFERIRASG AQIVTVAMGS PRQEILMRDC
     QAYYPQALYM GVGGTYDVFT GRVRRAPLLW RRFGLEWLYR LLSQPTRWRR QVKLLRFVAY
     YYAGKL
//

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