(data stored in SCRATCH zone)

SWISSPROT: C5DCF8_LACTC

ID   C5DCF8_LACTC            Unreviewed;       697 AA.
AC   C5DCF8;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   08-MAY-2019, entry version 50.
DE   RecName: Full=AP complex subunit beta {ECO:0000256|PIRNR:PIRNR002291};
GN   OrderedLocusNames=KLTH0B02706g {ECO:0000313|EMBL:CAR21469.1};
OS   Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)
OS   (Yeast) (Kluyveromyces thermotolerans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
OC   Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Lachancea.
OX   NCBI_TaxID=559295 {ECO:0000313|EMBL:CAR21469.1, ECO:0000313|Proteomes:UP000002036};
RN   [1] {ECO:0000313|EMBL:CAR21469.1, ECO:0000313|Proteomes:UP000002036}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 56472 / CBS 6340 / NRRL Y-8284
RC   {ECO:0000313|Proteomes:UP000002036};
RX   PubMed=19525356; DOI=10.1101/gr.091546.109;
RG   The Genolevures Consortium;
RA   Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA   Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P.,
RA   Jubin C., Poulain J., Barbe V., Segurens B., Artiguenave F.,
RA   Anthouard V., Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R.,
RA   Durrens P., Jean G., Marck C., Martin T., Nikolski M., Rolland T.,
RA   Seret M.-L., Casaregola S., Despons L., Fairhead C., Fischer G.,
RA   Lafontaine I., Leh V., Lemaire M., de Montigny J., Neuveglise C.,
RA   Thierry A., Blanc-Lenfle I., Bleykasten C., Diffels J., Fritsch E.,
RA   Frangeul L., Goeffon A., Jauniaux N., Kachouri-Lafond R., Payen C.,
RA   Potier S., Pribylova L., Ozanne C., Richard G.-F., Sacerdot C.,
RA   Straub M.-L., Talla E.;
RT   "Comparative genomics of protoploid Saccharomycetaceae.";
RL   Genome Res. 19:1696-1709(2009).
CC   -!- FUNCTION: Adaptins are components of the adaptor complexes which
CC       link clathrin to receptors in coated vesicles. Clathrin-associated
CC       protein complexes are believed to interact with the cytoplasmic
CC       tails of membrane proteins, leading to their selection and
CC       concentration. {ECO:0000256|PIRNR:PIRNR002291}.
CC   -!- SIMILARITY: Belongs to the adaptor complexes large subunit family.
CC       {ECO:0000256|PIRNR:PIRNR002291}.
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DR   EMBL; CU928166; CAR21469.1; -; Genomic_DNA.
DR   RefSeq; XP_002551907.1; XM_002551861.1.
DR   STRING; 381046.XP_002551907.1; -.
DR   EnsemblFungi; CAR21469; CAR21469; KLTH0B02706g.
DR   GeneID; 8290738; -.
DR   KEGG; lth:KLTH0B02706g; -.
DR   HOGENOM; HOG000163270; -.
DR   InParanoid; C5DCF8; -.
DR   OMA; ICHEYVR; -.
DR   OrthoDB; 323029at2759; -.
DR   Proteomes; UP000002036; Chromosome B.
DR   GO; GO:0030117; C:membrane coat; IEA:InterPro.
DR   GO; GO:0030276; F:clathrin binding; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   Gene3D; 1.25.10.10; -; 1.
DR   InterPro; IPR026739; AP_beta.
DR   InterPro; IPR016342; AP_complex_bsu_1_2_4.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR002553; Clathrin/coatomer_adapt-like_N.
DR   PANTHER; PTHR11134; PTHR11134; 1.
DR   Pfam; PF01602; Adaptin_N; 1.
DR   PIRSF; PIRSF002291; AP_complex_beta; 1.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   3: Inferred from homology;
DR   PRODOM; C5DCF8.
DR   SWISS-2DPAGE; C5DCF8.
KW   Complete proteome {ECO:0000313|Proteomes:UP000002036};
KW   Membrane {ECO:0000256|PIRNR:PIRNR002291,
KW   ECO:0000256|SAAS:SAAS00468874};
KW   Protein transport {ECO:0000256|PIRNR:PIRNR002291,
KW   ECO:0000256|SAAS:SAAS00299732};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002036};
KW   Transport {ECO:0000256|PIRNR:PIRNR002291,
KW   ECO:0000256|SAAS:SAAS00468876}.
FT   DOMAIN       22    540       Adaptin_N. {ECO:0000259|Pfam:PF01602}.
SQ   SEQUENCE   697 AA;  79127 MW;  FD12B6FFCF83CE04 CRC64;
     MSELRLFSKC KAYEIRAELQ QTNIKKHRAS ATKRKDALRK IIANLSMGNF GEMALLFPDV
     LRFWQVEDDL EVKRICHHYL VAMAPTKSGH FATALSMVLE DFNSGTEAVQ ILALRTLSSV
     PLPAYLEEAS KCASAVLHQH SEPEALKKAA LYALLRLAQL DSERSQLLMG IVGKVLQSAK
     EKPSVRAHAL FVLYQEEESS SETRTMGLGR DLCLSMLELL PRLNEWDNGR VLDALTANYV
     PQTHDDAHFM IDKALPQLQH ANTSVVLNAL KLIVFLTNYV DRLSESIVKQ LSSSVISLLN
     KPPELQFLVL RNVILLLLGR EKPLLKVDVP YFFVEFNDPI YIKDTKLEIL YLLAKEDNLA
     QIFQELKEYA TDIDIQMSRK AIRAVGNLAV KLKNSVDECI NLLLDLLDFE VEYIVQEIIS
     VFKNVLRRYP EKSKLCLYKL VRFTDSVQEP ESRSSMIWII TQYSSQLPNY FELFEGFSNN
     FLEESLEVQF TILSSTVKLF TRHPTPATEK LCINILKSST EKLDNPDLRD RAFMYWRLLS
     CTQKSGGNIL TMDAVREVVD GNLPLITLNS RLDPHVIEEL ELSIGTIVSI YLKPVNQVFR
     LNKPRVLPKS PALNSDKDNL EIIADDTRSH SSSFTDDSSL ASRRQSSSPV KKMDDYDRPA
     EVVNQLKLKR KTSSATSLLS RKPSVLGRKL SMKRPFG
//

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