(data stored in SCRATCH zone)

SWISSPROT: C5DCL7_LACTC

ID   C5DCL7_LACTC            Unreviewed;       278 AA.
AC   C5DCL7;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   11-DEC-2019, entry version 54.
DE   RecName: Full=Chromosome segregation in meiosis protein {ECO:0000256|RuleBase:RU366049};
GN   OrderedLocusNames=KLTH0B04092g {ECO:0000313|EMBL:CAR21528.1};
OS   Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)
OS   (Yeast) (Kluyveromyces thermotolerans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Lachancea.
OX   NCBI_TaxID=559295 {ECO:0000313|EMBL:CAR21528.1, ECO:0000313|Proteomes:UP000002036};
RN   [1] {ECO:0000313|EMBL:CAR21528.1, ECO:0000313|Proteomes:UP000002036}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 56472 / CBS 6340 / NRRL Y-8284
RC   {ECO:0000313|Proteomes:UP000002036};
RX   PubMed=19525356; DOI=10.1101/gr.091546.109;
RG   The Genolevures Consortium;
RA   Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA   Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA   Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA   Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA   Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA   Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA   Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA   Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA   Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA   Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT   "Comparative genomics of protoploid Saccharomycetaceae.";
RL   Genome Res. 19:1696-1709(2009).
CC   -!- FUNCTION: Plays an important role in the control of DNA replication and
CC       the maintenance of replication fork stability.
CC       {ECO:0000256|RuleBase:RU366049}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU366049}.
CC   -!- SIMILARITY: Belongs to the CSM3 family.
CC       {ECO:0000256|RuleBase:RU366049}.
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DR   EMBL; CU928166; CAR21528.1; -; Genomic_DNA.
DR   RefSeq; XP_002551966.1; XM_002551920.1.
DR   STRING; 381046.XP_002551966.1; -.
DR   EnsemblFungi; CAR21528; CAR21528; KLTH0B04092g.
DR   GeneID; 8290801; -.
DR   KEGG; lth:KLTH0B04092g; -.
DR   InParanoid; C5DCL7; -.
DR   KO; K10998; -.
DR   OMA; YNITRRA; -.
DR   OrthoDB; 1478452at2759; -.
DR   Proteomes; UP000002036; Chromosome B.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0000076; P:DNA replication checkpoint; IEA:UniProtKB-UniRule.
DR   GO; GO:0048478; P:replication fork protection; IEA:UniProtKB-UniRule.
DR   InterPro; IPR012923; Csm3.
DR   InterPro; IPR040038; TIPIN/Csm3/Swi3.
DR   PANTHER; PTHR13220; PTHR13220; 1.
DR   Pfam; PF07962; Swi3; 1.
PE   3: Inferred from homology;
DR   PRODOM; C5DCL7.
DR   SWISS-2DPAGE; C5DCL7.
KW   Cell cycle {ECO:0000256|RuleBase:RU366049};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   DNA damage {ECO:0000256|RuleBase:RU366049};
KW   Nucleus {ECO:0000256|RuleBase:RU366049};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002036}.
FT   DOMAIN          59..142
FT                   /note="Swi3"
FT                   /evidence="ECO:0000259|Pfam:PF07962"
FT   REGION          1..50
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          154..195
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          208..278
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          131..151
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        1..28
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        241..255
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   278 AA;  30540 MW;  FBCDE23F952DD868 CRC64;
     MSQQLQERFS DGTALSQDPD SSLLVDPTAI NPSGLGPDGD APLQDPTAVT TRVRRPQVKL
     TAEKLCSAKG LPAVMKHAPR RLRISKRRSS YDNLCHLLQF YQLWAHDLYP KAKFHDFVEL
     CRNLGKTDPQ LREYRIELLR QELEMGSALE EGAPAFPQER SPAPEPTPDA PGIADLRSEP
     PSPAPAPAGA DSDDDLIYNI TRRAPARVLH DSDIDEDSLM ETQPPASSTA GDAPRSAESG
     PGPILNNNNN NNNNNKNNDD DDDDEDEDEL AVMREMGL
//

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