(data stored in SCRATCH zone)

SWISSPROT: C6AY94_RHILS

ID   C6AY94_RHILS            Unreviewed;       239 AA.
AC   C6AY94;
DT   01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT   01-SEP-2009, sequence version 1.
DT   07-JUN-2017, entry version 53.
DE   RecName: Full=Ribonuclease PH {ECO:0000256|HAMAP-Rule:MF_00564, ECO:0000256|SAAS:SAAS00654476};
DE            Short=RNase PH {ECO:0000256|HAMAP-Rule:MF_00564};
DE            EC=2.7.7.56 {ECO:0000256|HAMAP-Rule:MF_00564, ECO:0000256|SAAS:SAAS00654472};
DE   AltName: Full=tRNA nucleotidyltransferase {ECO:0000256|HAMAP-Rule:MF_00564};
GN   Name=rph {ECO:0000256|HAMAP-Rule:MF_00564};
GN   OrderedLocusNames=Rleg_0006 {ECO:0000313|EMBL:ACS54318.1};
OS   Rhizobium leguminosarum bv. trifolii (strain WSM1325).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX   NCBI_TaxID=395491 {ECO:0000313|EMBL:ACS54318.1, ECO:0000313|Proteomes:UP000002256};
RN   [1] {ECO:0000313|EMBL:ACS54318.1, ECO:0000313|Proteomes:UP000002256}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WSM1325 {ECO:0000313|EMBL:ACS54318.1,
RC   ECO:0000313|Proteomes:UP000002256};
RX   PubMed=21304718;
RA   Reeve W., O'Hara G., Chain P., Ardley J., Brau L., Nandesena K.,
RA   Tiwari R., Copeland A., Nolan M., Han C., Brettin T., Land M.,
RA   Ovchinikova G., Ivanova N., Mavromatis K., Markowitz V., Kyrpides N.,
RA   Melino V., Denton M., Yates R., Howieson J.;
RT   "Complete genome sequence of Rhizobium leguminosarum bv. trifolii
RT   strain WSM1325, an effective microsymbiont of annual Mediterranean
RT   clovers.";
RL   Stand. Genomic Sci. 2:347-356(2010).
CC   -!- FUNCTION: Phosphorolytic exoribonuclease that removes nucleotide
CC       residues following the -CCA terminus of tRNA and adds nucleotides
CC       to the ends of RNA molecules by using nucleoside diphosphates as
CC       substrates. {ECO:0000256|HAMAP-Rule:MF_00564,
CC       ECO:0000256|SAAS:SAAS00654485}.
CC   -!- CATALYTIC ACTIVITY: tRNA(n+1) + phosphate = tRNA(n) + a nucleoside
CC       diphosphate. {ECO:0000256|HAMAP-Rule:MF_00564,
CC       ECO:0000256|SAAS:SAAS00654471}.
CC   -!- SIMILARITY: Belongs to the RNase PH family. {ECO:0000256|HAMAP-
CC       Rule:MF_00564, ECO:0000256|SAAS:SAAS00654479}.
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DR   EMBL; CP001622; ACS54318.1; -; Genomic_DNA.
DR   RefSeq; WP_012755758.1; NC_012850.1.
DR   ProteinModelPortal; C6AY94; -.
DR   EnsemblBacteria; ACS54318; ACS54318; Rleg_0006.
DR   KEGG; rlg:Rleg_0006; -.
DR   HOGENOM; HOG000229516; -.
DR   KO; K00989; -.
DR   OMA; KGKGQGW; -.
DR   OrthoDB; POG091H03ML; -.
DR   Proteomes; UP000002256; Chromosome.
DR   GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0009022; F:tRNA nucleotidyltransferase activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-HAMAP.
DR   CDD; cd11362; RNase_PH_bact; 1.
DR   Gene3D; 3.30.230.70; -; 1.
DR   HAMAP; MF_00564; RNase_PH; 1.
DR   InterPro; IPR001247; ExoRNase_PH_dom1.
DR   InterPro; IPR015847; ExoRNase_PH_dom2.
DR   InterPro; IPR027408; PNPase/RNase_PH_dom.
DR   InterPro; IPR020568; Ribosomal_S5_D2-typ_fold.
DR   InterPro; IPR002381; RNase_PH_bac-type.
DR   InterPro; IPR018336; RNase_PH_CS.
DR   Pfam; PF01138; RNase_PH; 1.
DR   Pfam; PF03725; RNase_PH_C; 1.
DR   SUPFAM; SSF54211; SSF54211; 1.
DR   SUPFAM; SSF55666; SSF55666; 1.
DR   TIGRFAMs; TIGR01966; RNasePH; 1.
DR   PROSITE; PS01277; RIBONUCLEASE_PH; 1.
PE   3: Inferred from homology;
DR   PRODOM; C6AY94.
DR   SWISS-2DPAGE; C6AY94.
KW   Complete proteome {ECO:0000313|Proteomes:UP000002256};
KW   Nucleotidyltransferase {ECO:0000256|HAMAP-Rule:MF_00564,
KW   ECO:0000256|SAAS:SAAS00654484, ECO:0000313|EMBL:ACS54318.1};
KW   Transferase {ECO:0000256|HAMAP-Rule:MF_00564,
KW   ECO:0000256|SAAS:SAAS00654470, ECO:0000313|EMBL:ACS54318.1};
KW   tRNA processing {ECO:0000256|HAMAP-Rule:MF_00564,
KW   ECO:0000256|SAAS:SAAS00654473}.
FT   DOMAIN       10    140       RNase_PH. {ECO:0000259|Pfam:PF01138}.
FT   DOMAIN      160    224       RNase_PH_C. {ECO:0000259|Pfam:PF03725}.
SQ   SEQUENCE   239 AA;  26113 MW;  0111FF7B7511D1A6 CRC64;
     MRPSGRKIDQ MRKVSFERNF SKHAEGSCLV KFGDTHVLCT ASLEEKTPPW LRNTGKGWVT
     AEYGMLPRAT GERMKREAAA GKQGGRTQEI QRLIGRSLRA VVDLQALGER QITLDCDVIQ
     ADGGTRTASI TGGWIALYDC LKWMESRNMI KVERVLKDHV AAISCGIFAS QPVIDLDYIE
     DSSAETDANF VMTGTGGIVE IQGTAEGTPF SEGEFTSLMQ LARNGIGELV ALQKQAVEG
//

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