(data stored in ACNUC1104 zone)

SWISSPROT: C7NFY0_KYTSD

ID   C7NFY0_KYTSD            Unreviewed;       494 AA.
AC   C7NFY0;
DT   13-OCT-2009, integrated into UniProtKB/TrEMBL.
DT   13-OCT-2009, sequence version 1.
DT   10-APR-2019, entry version 51.
DE   SubName: Full=Drug resistance transporter, EmrB/QacA subfamily {ECO:0000313|EMBL:ACV05980.1};
GN   OrderedLocusNames=Ksed_09340 {ECO:0000313|EMBL:ACV05980.1};
OS   Kytococcus sedentarius (strain ATCC 14392 / DSM 20547 / CCM 314 / 541)
OS   (Micrococcus sedentarius).
OC   Bacteria; Actinobacteria; Micrococcales; Dermacoccaceae; Kytococcus.
OX   NCBI_TaxID=478801 {ECO:0000313|EMBL:ACV05980.1, ECO:0000313|Proteomes:UP000006666};
RN   [1] {ECO:0000313|EMBL:ACV05980.1, ECO:0000313|Proteomes:UP000006666}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 14392 / DSM 20547 / CCM 314 / 541
RC   {ECO:0000313|Proteomes:UP000006666};
RX   PubMed=21304632; DOI=10.4056/sigs.761;
RA   Sims D., Brettin T., Detter J.C., Han C., Lapidus A., Copeland A.,
RA   Glavina Del Rio T., Nolan M., Chen F., Lucas S., Tice H., Cheng J.F.,
RA   Bruce D., Goodwin L., Pitluck S., Ovchinnikova G., Pati A.,
RA   Ivanova N., Mavrommatis K., Chen A., Palaniappan K., D'haeseleer P.,
RA   Chain P., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA   Schneider S., Goker M., Pukall R., Kyrpides N.C., Klenk H.P.;
RT   "Complete genome sequence of Kytococcus sedentarius type strain
RT   (541).";
RL   Stand. Genomic Sci. 1:12-20(2009).
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC       {ECO:0000256|SAAS:SAAS00769108}.
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DR   EMBL; CP001686; ACV05980.1; -; Genomic_DNA.
DR   RefSeq; WP_012802394.1; NC_013169.1.
DR   STRING; 478801.Ksed_09340; -.
DR   EnsemblBacteria; ACV05980; ACV05980; Ksed_09340.
DR   KEGG; kse:Ksed_09340; -.
DR   eggNOG; ENOG4105C0R; Bacteria.
DR   eggNOG; ENOG410XNN3; LUCA.
DR   HOGENOM; HOG000239124; -.
DR   OMA; SWLCGIS; -.
DR   OrthoDB; 1108236at2; -.
DR   BioCyc; KSED478801:G1GFM-911-MONOMER; -.
DR   Proteomes; UP000006666; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd06174; MFS; 1.
DR   InterPro; IPR004638; EmrB-like.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   TIGRFAMs; TIGR00711; efflux_EmrB; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
DR   PRODOM; C7NFY0.
DR   SWISS-2DPAGE; C7NFY0.
KW   Cell membrane {ECO:0000256|SAAS:SAAS00769078};
KW   Complete proteome {ECO:0000313|Proteomes:UP000006666};
KW   Membrane {ECO:0000256|SAAS:SAAS00769060, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006666};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00769091,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00769070,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00769034}.
FT   TRANSMEM     12     32       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     44     65       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     77     96       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    135    153       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    165    185       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    197    215       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    227    248       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    269    292       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    304    322       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    334    353       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    359    377       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    464    485       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       11    486       MFS. {ECO:0000259|PROSITE:PS50850}.
SQ   SEQUENCE   494 AA;  51629 MW;  63ACE3FE6E224474 CRC64;
     MTPPPVRPWP ALWALCLGFF MVLVDSTIVS IATPALMREF DASVSHVVWV TSAYLLAYAV
     PLLVTGRLGD RLGPKRLYLA GLGVFTAASA WCGLADSIEA LIAARVLQGL GAAMLSPQTM
     AVITRLFPGN QRGRAMAAWG ATAGAATLVG PLMGGVLLDS AGWEWIFFVN VPVGILAMVL
     AARLVPALGT RAHSMDWWGV ALSAVGMFLL VFGIQEGQTY RWGTITGWVS VPLLIAVGLV
     VLTVFVVWQA CNTREPLVPL RLFTHRNFSL ANVAITTVGF ATIATAFPFI LYLQSVRGMT
     PTEAALVMAP SSVMTLLLAR WAGGLVDRVH PRTLASIGMV GLALTYLFVA LTVRPGTPLP
     VLLVPWFMLG ITSSFVWSPL SVSATRTLPP HAIGAGSGVY NTTRQVGSVL GAAAIAALIE
     ARMVAHLGGA PGAGAPAGEA MAHTAVRVSP AVAEQMSAAL RESLYVPAAV LVVGAVAALL
     LVGHADDPDT FEAG
//

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