(data stored in SCRATCH zone)

SWISSPROT: C7PVC9_CATAD

ID   C7PVC9_CATAD            Unreviewed;       460 AA.
AC   C7PVC9;
DT   13-OCT-2009, integrated into UniProtKB/TrEMBL.
DT   13-OCT-2009, sequence version 1.
DT   08-MAY-2019, entry version 64.
DE   RecName: Full=Replicative DNA helicase {ECO:0000256|RuleBase:RU362085};
DE            EC=3.6.4.12 {ECO:0000256|RuleBase:RU362085};
GN   OrderedLocusNames=Caci_0332 {ECO:0000313|EMBL:ACU69285.1};
OS   Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC
OS   102108 / JCM 14897).
OC   Bacteria; Actinobacteria; Catenulisporales; Catenulisporaceae;
OC   Catenulispora.
OX   NCBI_TaxID=479433 {ECO:0000313|EMBL:ACU69285.1, ECO:0000313|Proteomes:UP000000851};
RN   [1] {ECO:0000313|EMBL:ACU69285.1, ECO:0000313|Proteomes:UP000000851}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897
RC   {ECO:0000313|Proteomes:UP000000851};
RX   PubMed=21304647;
RA   Copeland A., Lapidus A., Glavina Del Rio T., Nolan M., Lucas S.,
RA   Chen F., Tice H., Cheng J.F., Bruce D., Goodwin L., Pitluck S.,
RA   Mikhailova N., Pati A., Ivanova N., Mavromatis K., Chen A.,
RA   Palaniappan K., Chain P., Land M., Hauser L., Chang Y.J.,
RA   Jeffries C.D., Chertkov O., Brettin T., Detter J.C., Han C., Ali Z.,
RA   Tindall B.J., Goker M., Bristow J., Eisen J.A., Markowitz V.,
RA   Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT   "Complete genome sequence of Catenulispora acidiphila type strain (ID
RT   139908).";
RL   Stand. Genomic Sci. 1:119-125(2009).
CC   -!- FUNCTION: Participates in initiation and elongation during
CC       chromosome replication; it exhibits DNA-dependent ATPase activity.
CC       {ECO:0000256|RuleBase:RU362085}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC         Evidence={ECO:0000256|RuleBase:RU362085};
CC   -!- SIMILARITY: Belongs to the helicase family. DnaB subfamily.
CC       {ECO:0000256|RuleBase:RU362085}.
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DR   EMBL; CP001700; ACU69285.1; -; Genomic_DNA.
DR   RefSeq; WP_012784580.1; NC_013131.1.
DR   STRING; 479433.Caci_0332; -.
DR   EnsemblBacteria; ACU69285; ACU69285; Caci_0332.
DR   KEGG; cai:Caci_0332; -.
DR   eggNOG; ENOG4105CDU; Bacteria.
DR   eggNOG; COG0305; LUCA.
DR   HOGENOM; HOG000113195; -.
DR   KO; K02314; -.
DR   OMA; FQIAEAR; -.
DR   OrthoDB; 1709134at2; -.
DR   BioCyc; CACI479433:G1GFP-336-MONOMER; -.
DR   Proteomes; UP000000851; Chromosome.
DR   GO; GO:1990077; C:primosome complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006269; P:DNA replication, synthesis of RNA primer; IEA:UniProtKB-UniRule.
DR   CDD; cd00984; DnaB_C; 1.
DR   Gene3D; 1.10.860.10; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR036185; DNA_heli_DnaB-like_N_sf.
DR   InterPro; IPR007692; DNA_helicase_DnaB.
DR   InterPro; IPR007694; DNA_helicase_DnaB-like_C.
DR   InterPro; IPR007693; DNA_helicase_DnaB-like_N.
DR   InterPro; IPR016136; DNA_helicase_N/primase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00772; DnaB; 1.
DR   Pfam; PF03796; DnaB_C; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF48024; SSF48024; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00665; DnaB; 1.
DR   PROSITE; PS51199; SF4_HELICASE; 1.
PE   3: Inferred from homology;
DR   PRODOM; C7PVC9.
DR   SWISS-2DPAGE; C7PVC9.
KW   ATP-binding {ECO:0000256|RuleBase:RU362085};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000851};
KW   DNA replication {ECO:0000256|RuleBase:RU362085,
KW   ECO:0000256|SAAS:SAAS00740714};
KW   DNA-binding {ECO:0000256|RuleBase:RU362085,
KW   ECO:0000256|SAAS:SAAS00740674};
KW   Helicase {ECO:0000256|RuleBase:RU362085, ECO:0000313|EMBL:ACU69285.1};
KW   Hydrolase {ECO:0000256|RuleBase:RU362085};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU362085};
KW   Primosome {ECO:0000256|RuleBase:RU362085};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000851}.
FT   DOMAIN      192    460       SF4 helicase. {ECO:0000259|PROSITE:
FT                                PS51199}.
SQ   SEQUENCE   460 AA;  50639 MW;  F9816FBF84CE0156 CRC64;
     MSIDDLPYTA DEAYQGGFER TPPQDIPAEQ SVLGGMLLSK DAIAEVIEVI KAIDFYKPAH
     EAVFGAILEL YGRGEPADPV TVAALLTKKG DINRIGGAPY LHTLINSVPT AANAGYYAEI
     VKERAVLRRL VEAGTRIVQM GYSTDGSDVE QIVDAAQQEM YNVTEARTSE DFIPLADAME
     GALDEIESIS NRSGQMTGVP TGFHDLDALT NGLHPGQMVI IAARPAIGKS TLGLDLARSC
     SIKNGLTSVI FSLEMGRNEI IMRLLSAEAR VALHHMRSGT MTDEDWARLA RRMGPVSEAP
     LFIDDSPNMS MMEIRAKARR LKQRHDLQLV IIDYMQLMQH SSSNSKRPDS RQQEVSEISR
     SLKLLAKELE VPVIAISQLN RGPEQRTDKR PMMSDLRESG SLEQDADVII LLHREDAYER
     ESPRAGEADL IVAKHRNGPT ANITVAFQGH YSRFVDMAQS
//

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