(data stored in ACNUC1104 zone)

SWISSPROT: C7QBT0_CATAD

ID   C7QBT0_CATAD            Unreviewed;       486 AA.
AC   C7QBT0;
DT   13-OCT-2009, integrated into UniProtKB/TrEMBL.
DT   13-OCT-2009, sequence version 1.
DT   08-MAY-2019, entry version 53.
DE   SubName: Full=Drug resistance transporter, EmrB/QacA subfamily {ECO:0000313|EMBL:ACU72549.1};
GN   OrderedLocusNames=Caci_3647 {ECO:0000313|EMBL:ACU72549.1};
OS   Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC
OS   102108 / JCM 14897).
OC   Bacteria; Actinobacteria; Catenulisporales; Catenulisporaceae;
OC   Catenulispora.
OX   NCBI_TaxID=479433 {ECO:0000313|EMBL:ACU72549.1, ECO:0000313|Proteomes:UP000000851};
RN   [1] {ECO:0000313|EMBL:ACU72549.1, ECO:0000313|Proteomes:UP000000851}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897
RC   {ECO:0000313|Proteomes:UP000000851};
RX   PubMed=21304647;
RA   Copeland A., Lapidus A., Glavina Del Rio T., Nolan M., Lucas S.,
RA   Chen F., Tice H., Cheng J.F., Bruce D., Goodwin L., Pitluck S.,
RA   Mikhailova N., Pati A., Ivanova N., Mavromatis K., Chen A.,
RA   Palaniappan K., Chain P., Land M., Hauser L., Chang Y.J.,
RA   Jeffries C.D., Chertkov O., Brettin T., Detter J.C., Han C., Ali Z.,
RA   Tindall B.J., Goker M., Bristow J., Eisen J.A., Markowitz V.,
RA   Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT   "Complete genome sequence of Catenulispora acidiphila type strain (ID
RT   139908).";
RL   Stand. Genomic Sci. 1:119-125(2009).
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC       {ECO:0000256|SAAS:SAAS00769108}.
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DR   EMBL; CP001700; ACU72549.1; -; Genomic_DNA.
DR   RefSeq; WP_015792278.1; NC_013131.1.
DR   STRING; 479433.Caci_3647; -.
DR   EnsemblBacteria; ACU72549; ACU72549; Caci_3647.
DR   KEGG; cai:Caci_3647; -.
DR   eggNOG; ENOG4105C0R; Bacteria.
DR   eggNOG; ENOG410XNN3; LUCA.
DR   HOGENOM; HOG000239124; -.
DR   OrthoDB; 1108236at2; -.
DR   BioCyc; CACI479433:G1GFP-3665-MONOMER; -.
DR   Proteomes; UP000000851; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd06174; MFS; 1.
DR   InterPro; IPR004638; EmrB-like.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 2.
DR   TIGRFAMs; TIGR00711; efflux_EmrB; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
DR   PRODOM; C7QBT0.
DR   SWISS-2DPAGE; C7QBT0.
KW   Cell membrane {ECO:0000256|SAAS:SAAS00769078};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000851};
KW   Membrane {ECO:0000256|SAAS:SAAS00769060, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000851};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00769091,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00769070,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00769034}.
FT   TRANSMEM     14     40       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     60     77       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     84    103       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    109    131       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    143    164       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    170    192       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    204    222       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    234    251       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    272    298       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    310    328       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    335    352       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    364    387       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    408    427       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    439    458       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       18    463       MFS. {ECO:0000259|PROSITE:PS50850}.
SQ   SEQUENCE   486 AA;  50228 MW;  2BBC6F302AFEC5DE CRC64;
     MSGTAITLPQ RKGVVGWTLA LAALGTFLPT LDIVVVSTAL PTLRTHLHAS LSDLEWTINS
     YNLVFAVFML TGAALGDRFG RKRLYVTGVT IFTAASLANA LATTSGELIT FRAIQGIGAA
     IILPLTVTLV ADVMPVEKRA MAIGLLGGVT GLGVAAGPVV GGAIVEGISW QWIFWLNVPV
     GIVIAIGSAV FLRESKGSRT YLDIPGLVLA GAAMFGLVWA AVRGPSIGWR TGEVAVSLIG
     GLVLIAAFIL WEQRTSTPML PVSYFRNRGF NGANWASYFM QISIIGSLFM ITQLFQIGMG
     YSPMTTGVRI LVWMAMPMLV APPGGILAGK LGNRPVLLVG LTLQAAGLAW LAEAVHVGVG
     YGSMVGPLIV AGIGISLCFP VVSNAIVDSV PFEEIGVANG ANKTFVELGS VSGVAILSAV
     FASQGGYGSS AAFIDGFKPA MYTSAALAAV GLIGALMLPR GSAAQALQQQ AQLKQVAQAE
     PAAEGV
//

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