(data stored in SCRATCH zone)

SWISSPROT: VEG_BACSU

ID   VEG_BACSU               Reviewed;          86 AA.
AC   P37466;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1994, sequence version 1.
DT   11-DEC-2019, entry version 98.
DE   RecName: Full=Protein Veg;
GN   Name=veg; OrderedLocusNames=BSU00440;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=7584024; DOI=10.1093/dnares/1.1.1;
RA   Ogasawara N., Nakai S., Yoshikawa H.;
RT   "Systematic sequencing of the 180 kilobase region of the Bacillus subtilis
RT   chromosome containing the replication origin.";
RL   DNA Res. 1:1-14(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-26.
RX   PubMed=6181373; DOI=10.1007/bf00729452;
RA   Moran C.P. Jr., Lang N., LeGrice S.F.J., Lee G., Stephens M.,
RA   Sonenshein A.L., Pero J., Losick R.;
RT   "Nucleotide sequences that signal the initiation of transcription and
RT   translation in Bacillus subtilis.";
RL   Mol. Gen. Genet. 186:339-346(1982).
RN   [4]
RP   INDUCTION.
RX   PubMed=6790516;
RA   Ollington J.F., Losick R.;
RT   "A cloned gene that is turned on at an intermediate stage of spore
RT   formation in Bacillus subtilis.";
RL   J. Bacteriol. 147:443-451(1981).
RN   [5]
RP   SUBCELLULAR LOCATION, INDUCTION, AND DISRUPTION PHENOTYPE.
RC   STRAIN=168;
RX   PubMed=12761295; DOI=10.1093/jb/mvg062;
RA   Fukushima T., Ishikawa S., Yamamoto H., Ogasawara N., Sekiguchi J.;
RT   "Transcriptional, functional and cytochemical analyses of the veg gene in
RT   Bacillus subtilis.";
RL   J. Biochem. 133:475-483(2003).
RN   [6]
RP   FUNCTION IN BIOFILM FORMATION, AND DISRUPTION PHENOTYPE.
RC   STRAIN=168;
RX   PubMed=23378512; DOI=10.1128/jb.02201-12;
RA   Lei Y., Oshima T., Ogasawara N., Ishikawa S.;
RT   "Functional analysis of the protein Veg, which stimulates biofilm formation
RT   in Bacillus subtilis.";
RL   J. Bacteriol. 195:1697-1705(2013).
CC   -!- FUNCTION: Stimulates biofilm formation via transcriptional activation
CC       of extracellular matrix genes. Acts by repressing SinR activity,
CC       independently of the SinI, SlrA and SlrR pathways. Could also be
CC       involved in the regulation of other genes during biofilm and spore
CC       formation. {ECO:0000269|PubMed:23378512}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:12761295}. Spore
CC       core {ECO:0000269|PubMed:12761295}. Note=During sporulation,
CC       accumulates in the forespore compartment but not in the mother cell.
CC   -!- INDUCTION: Expressed during both vegetative growth phase and
CC       sporulation. {ECO:0000269|PubMed:12761295, ECO:0000269|PubMed:6790516}.
CC   -!- DISRUPTION PHENOTYPE: Mutants show poor germination in the presence of
CC       L-alanine and reduced biofilm formation. {ECO:0000269|PubMed:12761295,
CC       ECO:0000269|PubMed:23378512}.
DR   EMBL; D26185; BAA05279.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB11820.1; -; Genomic_DNA.
DR   EMBL; J01552; AAA22880.1; -; Genomic_DNA.
DR   PIR; S66073; S66073.
DR   RefSeq; NP_387925.1; NC_000964.3.
DR   RefSeq; WP_003218330.1; NZ_JNCM01000028.1.
DR   STRING; 224308.BSU00440; -.
DR   PaxDb; P37466; -.
DR   PRIDE; P37466; -.
DR   EnsemblBacteria; CAB11820; CAB11820; BSU00440.
DR   GeneID; 936744; -.
DR   GeneID; 9780452; -.
DR   KEGG; bsu:BSU00440; -.
DR   PATRIC; fig|224308.179.peg.44; -.
DR   eggNOG; ENOG4105W42; Bacteria.
DR   eggNOG; COG4466; LUCA.
DR   HOGENOM; HOG000204879; -.
DR   OMA; TVEIILC; -.
DR   PhylomeDB; P37466; -.
DR   BioCyc; BSUB:BSU00440-MONOMER; -.
DR   PRO; PR:P37466; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR   InterPro; IPR009366; Protein_Veg.
DR   PANTHER; PTHR40026; PTHR40026; 1.
DR   Pfam; PF06257; VEG; 1.
DR   PIRSF; PIRSF037257; DUF1021; 1.
PE   1: Evidence at protein level;
DR   PRODOM; P37466.
DR   SWISS-2DPAGE; P37466.
KW   Cytoplasm; Reference proteome; Sporulation.
FT   CHAIN           1..86
FT                   /note="Protein Veg"
FT                   /id="PRO_0000065778"
SQ   SEQUENCE   86 AA;  9550 MW;  4C9C650ECE7A6015 CRC64;
     MAKTLSDIKR SLDGNLGKRL TLKANGGRRK TIERSGILAE TYPSVFVIQL DQDENSFERV
     SYSYADILTE TVELTFNDDA ASSVAF
//

If you have problems or comments...

PBIL Back to PBIL home page