(data stored in ACNUC7421 zone)

SWISSPROT: NDHF_BACSU

ID   NDHF_BACSU              Reviewed;         505 AA.
AC   P39755;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 2.
DT   11-DEC-2019, entry version 116.
DE   RecName: Full=Probable NADH-quinone oxidoreductase subunit 5;
DE            EC=1.6.5.11;
DE   AltName: Full=NADH dehydrogenase subunit 5;
GN   Name=ndhF; Synonyms=ybxE; OrderedLocusNames=BSU01830;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=7565865; DOI=10.1016/0921-8777(95)00013-a;
RA   Morohoshi F., Munakata N.;
RT   "Diverse capacities for the adaptive response to DNA alkylation in Bacillus
RT   species and strains.";
RL   Mutat. Res. 337:97-110(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RA   Haga K., Liu H., Yasumoto K., Takahashi H., Yoshikawa H.;
RT   "Sequence analysis of the 70kb region between 17 and 23 degree of the
RT   Bacillus subtilis chromosome.";
RL   Submitted (JUL-1997) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-91.
RC   STRAIN=168;
RA   Morohoshi F., Munakata N.;
RL   Submitted (OCT-1993) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a quinone + H(+) + NADH = a quinol + NAD(+);
CC         Xref=Rhea:RHEA:46160, ChEBI:CHEBI:15378, ChEBI:CHEBI:24646,
CC         ChEBI:CHEBI:57540, ChEBI:CHEBI:57945, ChEBI:CHEBI:132124;
CC         EC=1.6.5.11;
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the complex I subunit 5 family. {ECO:0000305}.
DR   EMBL; U28323; AAA70186.1; -; Genomic_DNA.
DR   EMBL; AB006424; BAA33076.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB11959.1; -; Genomic_DNA.
DR   EMBL; D21197; BAA21007.1; -; Genomic_DNA.
DR   PIR; C69666; C69666.
DR   RefSeq; NP_388064.1; NC_000964.3.
DR   RefSeq; WP_003234919.1; NZ_JNCM01000030.1.
DR   STRING; 224308.BSU01830; -.
DR   PaxDb; P39755; -.
DR   PRIDE; P39755; -.
DR   EnsemblBacteria; CAB11959; CAB11959; BSU01830.
DR   GeneID; 938593; -.
DR   KEGG; bsu:BSU01830; -.
DR   PATRIC; fig|224308.179.peg.189; -.
DR   eggNOG; ENOG4108TWJ; Bacteria.
DR   eggNOG; COG1009; LUCA.
DR   HOGENOM; HOG000093379; -.
DR   InParanoid; P39755; -.
DR   KO; K05577; -.
DR   OMA; VHGWLIQ; -.
DR   PhylomeDB; P39755; -.
DR   BioCyc; BSUB:BSU01830-MONOMER; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0050136; F:NADH dehydrogenase (quinone) activity; IEA:UniProtKB-EC.
DR   GO; GO:0048038; F:quinone binding; IEA:UniProtKB-KW.
DR   InterPro; IPR001750; ND/Mrp_mem.
DR   InterPro; IPR001516; Proton_antipo_N.
DR   Pfam; PF00361; Proton_antipo_M; 1.
DR   Pfam; PF00662; Proton_antipo_N; 1.
PE   3: Inferred from homology;
DR   PRODOM; P39755.
DR   SWISS-2DPAGE; P39755.
KW   Cell membrane; Membrane; NAD; Oxidoreductase; Quinone; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..505
FT                   /note="Probable NADH-quinone oxidoreductase subunit 5"
FT                   /id="PRO_0000118225"
FT   TRANSMEM        9..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        37..57
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        68..88
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        123..143
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        162..182
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        204..224
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        232..252
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        259..279
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        303..323
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        355..375
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        410..430
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        446..466
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   505 AA;  55468 MW;  B62D1EE3B6004358 CRC64;
     MLVSLSLSSL LTLFFIMLMA SGISGLLFLH PRVPLSFVRI HIGILALPLL VSLLILANSG
     VSGNVGPWHL DSLACLMTFF VLAIGFIIQR FSVRYLMGDR SYRKYFTLFT FTTGAASMTW
     LSGDLRLMVL FWGATLVGLT LLIRLNSAWQ VASEAAKISG RLFLLSWFSL FFAMMWLFHA
     TGQWQLSLVV TNESLAGLGE WERTGIQLLI VLAVIIPAAQ WPFQRWLVES IVAPTPVSAI
     MHAGLVNAGG IILTRFSPLF HGGIASIILL LLASISVLIG TGISLVQVDY KRQLVGSTIG
     QMGFMLIQCA LGAYIAAIIH LILHGLFKAT LFLQAGSAVG RHEVSTRTNE RTSYLWVMAG
     RILSLVIGVA FWLTAPGDGY HLISALILGW SLSVSWDQLV AFGEGRIGRI AGLTVLGGAA
     LVYFIIHHLF YKWLHTTIFQ SVQPPMSAVM IVVCLLLFGS ALGTWVARHR SSVFFAVLYL
     WLVRLGEAKP KSVESHPDYL KQYIS
//

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