(data stored in SCRATCH zone)

SWISSPROT: YBEC_BACSU

ID   YBEC_BACSU              Reviewed;         539 AA.
AC   Q45577; Q7DL53;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   16-JUN-2009, sequence version 3.
DT   11-DEC-2019, entry version 112.
DE   RecName: Full=Probable amino acid-proton symporter YbeC;
GN   Name=ybeC; OrderedLocusNames=BSU02120;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RA   Haga K., Liu H., Yasumoto K., Takahashi H., Yoshikawa H.;
RT   "Sequence analysis of the 70kb region between 17 and 23 degree of the
RT   Bacillus subtilis chromosome.";
RL   Submitted (JUL-1997) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [3]
RP   SEQUENCE REVISION TO 319.
RX   PubMed=19383706; DOI=10.1099/mic.0.027839-0;
RA   Barbe V., Cruveiller S., Kunst F., Lenoble P., Meurice G., Sekowska A.,
RA   Vallenet D., Wang T., Moszer I., Medigue C., Danchin A.;
RT   "From a consortium sequence to a unified sequence: the Bacillus subtilis
RT   168 reference genome a decade later.";
RL   Microbiology 155:1758-1775(2009).
RN   [4]
RP   IDENTIFICATION.
RC   STRAIN=168;
RX   PubMed=12730183; DOI=10.1128/jb.185.10.3218-3222.2003;
RA   Lorca G., Winnen B., Saier M.H. Jr.;
RT   "Identification of the L-aspartate transporter in Bacillus subtilis.";
RL   J. Bacteriol. 185:3218-3222(2003).
CC   -!- FUNCTION: Uptake of an yet unknown amino-acid with the concomitant
CC       import of a proton. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC       superfamily. AGT (TC 2.A.3.11) family. {ECO:0000305}.
DR   EMBL; AB006424; BAA33109.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB12006.2; -; Genomic_DNA.
DR   PIR; D69748; D69748.
DR   RefSeq; NP_388094.2; NC_000964.3.
DR   RefSeq; WP_003246447.1; NZ_JNCM01000030.1.
DR   STRING; 224308.BSU02120; -.
DR   jPOST; Q45577; -.
DR   PaxDb; Q45577; -.
DR   PRIDE; Q45577; -.
DR   EnsemblBacteria; CAB12006; CAB12006; BSU02120.
DR   GeneID; 938442; -.
DR   KEGG; bsu:BSU02120; -.
DR   PATRIC; fig|224308.179.peg.218; -.
DR   eggNOG; ENOG4107QTZ; Bacteria.
DR   eggNOG; COG0531; LUCA.
DR   HOGENOM; HOG000173493; -.
DR   InParanoid; Q45577; -.
DR   OMA; HKAFGIH; -.
DR   PhylomeDB; Q45577; -.
DR   BioCyc; BSUB:BSU02120-MONOMER; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR   InterPro; IPR002293; AA/rel_permease1.
DR   Pfam; PF13520; AA_permease_2; 1.
DR   PIRSF; PIRSF006060; AA_transporter; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q45577.
DR   SWISS-2DPAGE; Q45577.
KW   Amino-acid transport; Cell membrane; Membrane; Reference proteome; Symport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..539
FT                   /note="Probable amino acid-proton symporter YbeC"
FT                   /id="PRO_0000360432"
FT   TRANSMEM        11..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        36..56
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        82..102
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        137..157
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        164..184
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        199..219
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        238..258
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        283..303
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        346..365
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        369..389
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        401..421
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        424..444
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        457..477
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        486..506
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        319
FT                   /note="I -> V (in Ref. 1; BAA33109)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   539 AA;  59212 MW;  76209D9A7996BE35 CRC64;
     MNQLHRRMGT FSLMMVGLGS MIGSGWLFGA WRAAQIAGPA AIISWVIGMV VILFIALSYS
     ELGSMFPEAG GMVKYTQYSH GSFIGFIAGW ANWIAIVSVI PVEAVASVQY MSSWPWEWAK
     WTSGLVKNGT LTGEGLAFAS VLLLIYFLLN YWTVNLFSKA NSLITIFKII IPGLTIGALL
     FVGFHGENFT GGQSIAPNGW ASVLTAVATS GIVFAFNGFQ SPINMAGEAK NPGKSIPIAV
     VGSLFVATVI YVLLQIAFIG AVNPSDIAHG WSHLNFNSPF ADLAIALNIN WLVIVLYADA
     FVSPSGTGIT YTATTSRMIY GMEKNKYMPS IFGKLHPIYG VPRQAMFFNL IVSFIFLFLF
     RGWGVLAEII SVATLISYIT GPITVMTLRR TGKDLYRPLR LKGLNVIAPL GFIFASLVLY
     WARWPLTGQV LFIILIGLPI YFYYQAKAKW KGFGRNFKAG VWMVFYLLAM MVISYLGSDK
     FGGLNVIHYG WDMVLIAMVS LVFYVWALKS GYQTEYLKDA KEINSQLLNG QSEAAAGKE
//

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