(data stored in ACNUC7421 zone)

SWISSPROT: GLPT_BACSU

ID   GLPT_BACSU              Reviewed;         444 AA.
AC   P37948;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1994, sequence version 1.
DT   11-DEC-2019, entry version 129.
DE   RecName: Full=Glycerol-3-phosphate transporter;
DE            Short=G-3-P transporter;
DE   AltName: Full=G-3-P permease;
GN   Name=glpT; Synonyms=ybeE; OrderedLocusNames=BSU02140;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168 / BR95;
RX   PubMed=8012593; DOI=10.1099/00221287-140-4-723;
RA   Nilsson R.P., Beijer L., Rutberg B.;
RT   "The glpT and glpQ genes of the glycerol regulon in Bacillus subtilis.";
RL   Microbiology 140:723-730(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RA   Haga K., Liu H., Yasumoto K., Takahashi H., Yoshikawa H.;
RT   "Sequence analysis of the 70kb region between 17 and 23 degree of the
RT   Bacillus subtilis chromosome.";
RL   Submitted (JUL-1997) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
CC   -!- FUNCTION: Responsible for glycerol-3-phosphate uptake.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC       Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family. {ECO:0000305}.
DR   EMBL; Z26522; CAA81291.1; -; Genomic_DNA.
DR   EMBL; AB006424; BAA33111.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB12008.1; -; Genomic_DNA.
DR   PIR; I40417; I40417.
DR   RefSeq; NP_388096.1; NC_000964.3.
DR   RefSeq; WP_003246460.1; NZ_JNCM01000030.1.
DR   STRING; 224308.BSU02140; -.
DR   PaxDb; P37948; -.
DR   PRIDE; P37948; -.
DR   EnsemblBacteria; CAB12008; CAB12008; BSU02140.
DR   GeneID; 938447; -.
DR   KEGG; bsu:BSU02140; -.
DR   PATRIC; fig|224308.179.peg.220; -.
DR   eggNOG; ENOG4105CXY; Bacteria.
DR   eggNOG; COG2271; LUCA.
DR   HOGENOM; HOG000274729; -.
DR   InParanoid; P37948; -.
DR   KO; K02445; -.
DR   OMA; SSIAIMF; -.
DR   PhylomeDB; P37948; -.
DR   BioCyc; BSUB:BSU02140-MONOMER; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015169; F:glycerol-3-phosphate transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006071; P:glycerol metabolic process; IEA:UniProtKB-KW.
DR   InterPro; IPR005267; G3P_transporter.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR021159; Sugar-P_transporter_CS.
DR   InterPro; IPR000849; Sugar_P_transporter.
DR   PANTHER; PTHR43826:SF6; PTHR43826:SF6; 1.
DR   Pfam; PF07690; MFS_1; 1.
DR   PIRSF; PIRSF002808; Hexose_phosphate_transp; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   TIGRFAMs; TIGR00712; glpT; 1.
DR   PROSITE; PS00942; GLPT; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
DR   PRODOM; P37948.
DR   SWISS-2DPAGE; P37948.
KW   Cell membrane; Glycerol metabolism; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..444
FT                   /note="Glycerol-3-phosphate transporter"
FT                   /id="PRO_0000199877"
FT   TOPO_DOM        1..36
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        37..57
FT                   /note="Helical; Name=1"
FT                   /evidence="ECO:0000250"
FT   TOPO_DOM        58..63
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        64..84
FT                   /note="Helical; Name=2"
FT                   /evidence="ECO:0000250"
FT   TOPO_DOM        85..93
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        94..112
FT                   /note="Helical; Name=3"
FT                   /evidence="ECO:0000250"
FT   TOPO_DOM        113..120
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        121..141
FT                   /note="Helical; Name=4"
FT                   /evidence="ECO:0000250"
FT   TOPO_DOM        142..160
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        161..180
FT                   /note="Helical; Name=5"
FT                   /evidence="ECO:0000250"
FT   TOPO_DOM        181..189
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        190..207
FT                   /note="Helical; Name=6"
FT                   /evidence="ECO:0000250"
FT   TOPO_DOM        208..261
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        262..282
FT                   /note="Helical; Name=7"
FT                   /evidence="ECO:0000250"
FT   TOPO_DOM        283..287
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        288..308
FT                   /note="Helical; Name=8"
FT                   /evidence="ECO:0000250"
FT   TOPO_DOM        309..321
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        322..341
FT                   /note="Helical; Name=9"
FT                   /evidence="ECO:0000250"
FT   TOPO_DOM        342..346
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        347..368
FT                   /note="Helical; Name=10"
FT                   /evidence="ECO:0000250"
FT   TOPO_DOM        369..387
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        388..409
FT                   /note="Helical; Name=11"
FT                   /evidence="ECO:0000250"
FT   TOPO_DOM        410..414
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        415..435
FT                   /note="Helical; Name=12"
FT                   /evidence="ECO:0000250"
FT   TOPO_DOM        436..444
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   444 AA;  49802 MW;  E776BAA5C71DB2BA CRC64;
     MLNIFKPAPH IERLDDSKMD AAYKRLRLQV FIGIFIGYAG YYLLRKNFAF AIPYLQEQGF
     SKTELGLVLA AVSIAYGFSK FIMGMVSDRC NPRYFLATGL FLSAIVNILF VSMPWVTSSV
     TIMFIFMFIN GWFQGMGWPP CGRTMAHWFS ISERGTKMSI WNVAHNIGGG ILAPLVTLGI
     AMFVTWKSVF FFPAIIAIII SFLIVLLVRD TPQSCGLPPI EEYRNDYPKH AFKNQEKELT
     TKEILFQYVL NNKFLWYIAF ANVFVYFVRY GVVDWAPTYL TEAKGFSPED SRWSYFLYEY
     AGIPGTILCG WISDRFFKSR RAPAGVLFMA GVFIAVLVYW LNPAGNPLVD NIALISIGFL
     IYGPVMLIGL QAIDLAPKKA AGTAAGLTGF FGYIGGSAFA NAIMGFVVDR FNWNGGFIML
     ISSCILAIVF LALTWNTGKR AEHV
//

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